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The emerging complexity of Open Science: assessing Intelligent Data Openness in Genomic Anthropology and Human Genomics. 开放科学的新兴复杂性:评估基因组人类学和人类基因组学中的智能数据开放性。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-12-22 DOI: 10.4436/JASS.99016
Paolo Anagnostou, Marco Capocasa, Francesca Brisighelli, Cinzia Battaggia, Giovanni Destro Bisol

In recent decades, the scientific community has become aware of the importance of science being effectively open in order to speed up scientific and technological progress. In this context, the achievement of a robust, effective and responsible form of data sharing is now widely acknowledged as a fundamental part of the research process. The production and resolution of human genomic data has steadily increased in recent years, mainly due to technological advances and decreasing costs of DNA genotyping and sequencing. There is, however, a downside to this process due to the huge increase in the complexity of the data and related metadata. This means it is advisable to go beyond traditional forms of sharing analysis, which have focused on data availability only. Here we present a pilot study that aims to complement a survey on the availability of data related to peer-reviewed publications with an analysis of their findability, accessibility, useability and assessability (according to the "intelligent data openness" scheme). Sharing rates in genomic anthropology (73.0%) were found to be higher than human genomics (32.4%), but lower than closely related research fields (from 96.8% to 79.2% for paleogenetics and evolutionary genetics, respectively). We discuss the privacy and methodological issues that could be linked to this finding. Comparisons of sharing rates across a wide range of disciplines has suggested that the idea of human genomics as a forerunner for the open data movement should be questioned. Finally, both in genomic anthropology and human genomics, findability and useability were found to be compliant with the expectations of an intelligent data openness, whereas only a minor part of studies met the need to make the data completely assessable.

近几十年来,科学界已经意识到科学有效开放对于加快科技进步的重要性。在此背景下,实现稳健、有效和负责任的数据共享形式已被广泛视为研究过程的基本组成部分。近年来,人类基因组数据的生产和分辨率稳步提高,这主要是由于技术进步以及 DNA 基因分型和测序成本的降低。然而,由于数据和相关元数据的复杂性大幅增加,这一过程也存在弊端。这意味着我们应该超越只关注数据可用性的传统共享分析形式。在此,我们介绍一项试点研究,该研究旨在通过对可查找性、可访问性、可使用性和可评估性(根据 "智能数据开放性 "计划)的分析,对同行评议出版物相关数据的可用性调查进行补充。结果发现,基因组人类学的共享率(73.0%)高于人类基因组学(32.4%),但低于密切相关的研究领域(古遗传学和进化遗传学的共享率分别为 96.8% 和 79.2%)。我们讨论了可能与这一发现有关的隐私和方法问题。对众多学科共享率的比较表明,人类基因组学作为开放数据运动先驱的观点应该受到质疑。最后,在基因组人类学和人类基因组学中,可查找性和可使用性都符合对智能数据开放的期望,而只有一小部分研究满足了使数据完全可评估的需求。
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引用次数: 0
Geometric Morphometrics of the human cervical vertebrae: sexual and population variations. 人类颈椎的几何形态计量学:性别和人群差异。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-12-17 DOI: 10.4436/JASS.99015
Carlos A Palancar, Daniel García-Martínez, David Cáceres-Monllor, Bernardo Perea-Pérez, Maria Teresa Ferreira, Markus Bastir

This study aims to carry out the first geometric morphometric analysis of the 3D size and shape of the full series of cervical vertebrae delving into variability related to sex and population background. For this reason, we analyzed the cervical vertebrae of both males and females belonging to Europeans, Africans, and Greenland Inuit. We 3D-scanned a total of 219 cervical vertebrae of males and females of three different modern human populations (European, African, and Inuit). A minimum of 72 landmarks and curve semilandmarks were positioned in each of the 3D vertebral models. Landmark configurations were analyzed following the standards of 3D Geometric Morphometrics to test for size and shape differences related to sex or population variation. Results show that male cervical vertebrae are consistently larger than in females while no regular shape differences are observed between males and females in any of the populations. Sex differences in cervical lordosis are thus not supported at the skeletal level of the 3D shape. On the other hand, there is no evidence for population-specific differences in size while shape does vary considerably, possibly also in relation to eco-geographic factors of overall trunk shape. Cervical vertebrae in cold-adapted Inuit were consistently shorter than in Europeans and Africans. The cervical spine may show a different pattern than the thoracic and lumbar spine, which might be related to stronger integration with the cranium, head mobility, and soft-tissue dependence. Our findings suggest that morpho-functional interpretations of the cervical spine based on vertebral skeletal morphology requires caution.

本研究旨在首次对全系列颈椎骨的三维尺寸和形状进行几何形态计量分析,深入研究与性别和人口背景相关的变异性。为此,我们分析了欧洲人、非洲人和格陵兰因纽特人的男性和女性颈椎骨。我们对三个不同现代人种群(欧洲人、非洲人和因纽特人)的男性和女性共 219 节颈椎骨进行了三维扫描。在每个三维脊椎模型中至少定位了 72 个地标和曲线半地标。按照三维几何形态计量学的标准对地标配置进行了分析,以检验与性别或种群变异有关的大小和形状差异。结果显示,男性颈椎一直比女性大,而在任何人群中都没有观察到男性和女性在形状上的规律性差异。因此,从三维形状的骨骼层面来看,颈椎前凸的性别差异并不成立。另一方面,没有证据表明特定种群在体型上存在差异,而在形状上确实存在很大差异,这可能也与躯干整体形状的生态地理因素有关。与欧洲人和非洲人相比,适应寒冷的因纽特人的颈椎一直较短。颈椎的形态可能与胸椎和腰椎不同,这可能与颈椎与颅骨的结合更紧密、头部的活动性和软组织的依赖性有关。我们的研究结果表明,根据脊椎骨骼形态来解释颈椎的形态功能需要谨慎。
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引用次数: 0
Multi-proxy analysis suggests Late Pleistocene affinities of human skeletal remains attributed to Balzi Rossi. 多代理分析表明,巴尔齐-罗西的人类骨骼遗骸与晚更新世有亲缘关系。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-12-10 DOI: 10.4436/JASS.99014
Margherita Micheletti Cremasco, Giuseppe D'Amore, Vitale Stefano Sparacello, Margherita Mussi, Manon Galland, Antonio Profico, Melchiorre Masali, Sylvia Di Marco, Roberto Micciché, Martin Friess, Luca Sineo

In two publications from 1967 and 1971, M. Masali described human skeletal remains presumed to have been found in the Balzi Rossi caves (Ventimiglia, Italy), based on a signed note dated to 1908. Since then, the remains - dubbed "Conio's Finds" and preserved at the University of Torino - had not been further studied. We performed a multidisciplinary investigation aimed at clarifying the geographical and chronological attribution of these specimens. Collagen extraction for AMS dating was unsuccessful, but we obtained two direct dates on the best- preserved crania via 231Pa/235U direct gamma-ray spectrometry (10,500±2,000 years BP and 12,500±2,500 years BP). We analyzed the metrics and morphology of the crania and femora by comparing them with samples belonging to the Upper Paleolithic, Mesolithic, and Neolithic periods, and evidenced that the "Conio's Finds" are morphologically more compatible with a Late Pleistocene rather than Holocene attribution. We analyzed the literature regarding the history of excavations at Balzi Rossi, and we propose that - if any credence should be given to the note accompanying the material - the remains may have been found in front of Grotta dei Fanciulli or Grotta del Caviglione, in the redeposited soil dug up during the installation of lime kilns carried out between the late 18th and the early 19th centuries. These hypotheses may be tested in the future by comparing the speleothem deposited on one of the crania and the remaining deposit at the site.

在 1967 年和 1971 年的两份出版物中,M. Masali 根据 1908 年的一份签名说明,描述了推测在巴尔齐罗西洞穴(意大利文蒂米利亚)发现的人类骨骼遗骸。此后,这些被称为 "科尼奥的发现 "并保存在都灵大学的遗骸一直没有得到进一步研究。我们开展了一项多学科调查,旨在明确这些标本的地理和年代归属。提取胶原蛋白进行 AMS 测定并不成功,但我们通过 231Pa/235U 直接伽马射线光谱测定法获得了保存最完好的头盖骨的两个直接年代(公元前 10,500±2,000 年和公元前 12,500±2,500 年)。我们将颅骨和股骨的度量和形态与旧石器时代上、中、新石器时代的样本进行了比较分析,证明 "科尼奥发现 "在形态上更符合晚更新世而非全新世的归属。我们分析了有关巴尔齐-罗西发掘历史的文献,并建议--如果材料所附的说明可信的话--这些遗骸可能是在 Grotta dei Fanciulli 或 Grotta del Caviglione 前面,18 世纪末至 19 世纪初安装石灰窑时挖出的重新堆积的土壤中发现的。这些假设可在将来通过比较沉积在其中一个颅骨上的岩浆和遗址中剩余的沉积物进行验证。
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引用次数: 0
Next questions in Molecular Anthropology. 分子人类学的下一个问题。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-10-21 DOI: 10.4436/JASS.99013
Luca Pagani, Giovanni Destro Bisol
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引用次数: 0
Biobank-scale datasets and their relevance to anthropology/popgen. 生物群规模的数据集及其与人类学/流行基因的相关性。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-10-04 DOI: 10.4436/JASS.99012
Francesco Montinaro
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引用次数: 0
Methodological challenges and opportunities for inferring human demography. 推断人类人口的方法挑战与机遇。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-10-02 DOI: 10.4436/JASS.99010
Garrett Hellenthal
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引用次数: 0
From domestication genomics towards molecular ecology of human environments. 从驯化基因组学到人类环境分子生态学。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-10-02 DOI: 10.4436/JASS.99007
Anders Bergström
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引用次数: 0
Complexity in human ancestral demography. 人类祖先人口结构的复杂性。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-10-02 DOI: 10.4436/JASS.99009
Aylwyn Scally
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引用次数: 0
Molecular Anthropology is dead, long live Molecular Anthropology. 分子人类学已死,分子人类学万岁。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-10-02 DOI: 10.4436/JASS.99008
Austin W Reynolds, Brenna M Henn
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引用次数: 0
Ancient Health Landscape: foundations and perspectives. 古代健康景观:基础与视角。
IF 1.8 2区 社会学 Q1 ANTHROPOLOGY Pub Date : 2021-10-02 DOI: 10.4436/JASS.99011
Christiana L Scheib
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引用次数: 0
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