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Enhancing in-hospital cardiac arrest outcomes through the Tele-ICU Model: A novel approach to CPR quality improvement in India 通过远程icu模式提高院内心脏骤停结果:印度CPR质量改善的新方法
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-07-03 DOI: 10.1016/j.hlpt.2025.101062
Sidney Hilker , Vishwanath Koppad , Lokesh MB , Carl Britto , Ryan CL Brewster

Introduction

In-hospital cardiac arrest is a substantial cause of morbidity and mortality in low- and middle-income countries. Telemedicine intensive care units (Tele-ICUs) may expand critical care capacity, however their impact on cardiac arrest management and outcomes has not been well-defined.

Methods

A tele-ICU network established in India provides 24/7 multidisciplinary monitoring and management via real-time audiovisual technology. Between September 2022-November 2023, six partner hospitals underwent tele-ICU implementation and participated in a spaced advanced cardiac life support (ACLS) curriculum, tailored to tele-ICU workflows. The study period spanned from three months prior to the bedside ACLS training (“pre-intervention”) to six months following completion (“post-intervention”). The impact of the intervention on return of spontaneous circulation (ROSC) rates and overall hospital mortality was assessed with multivariable logistic regression and interrupted time series analysis.

Results

Among a total of 163 cardiac arrest events (n = 52 pre-intervention, n = 111 pre-intervention), most took place within 5 days of ICU admission (83.4 %) and asystole (61.3 %) was the most common precipitating rhythm. Tele-ICU sites achieved significantly greater ROSC rates during the post-intervention (38.7 %) versus the pre-intervention (19.2 %) periods (adjusted odds ratio [aOR] 3.65 [95 % confidence interval [CI] 1.40–9.53]). This corresponded with an immediate 16.1 % (95 % CI 0.7 %-31.5 %) level increase without a significant trend change (-0.10 % [-0.97 %-0.77 %]). Overall hospital survival remained similar (4.5 % vs. 3.8 %; aOR 0.69 [95 % CI 0.08–5.72]) between study periods.

Conclusions

Tele-ICU implementation coupled with targeted ACLS training was associated with improvements in immediate in-hospital cardiac arrest outcomes, highlighting the potential of low-cost, technology-enabled care delivery models to optimize resuscitation performance in LMICs.
医院内心脏骤停是低收入和中等收入国家发病率和死亡率的一个重要原因。远程医疗重症监护病房(tele - icu)可以扩大重症监护能力,但其对心脏骤停管理和结果的影响尚未明确。方法在印度建立远程icu网络,通过实时视听技术提供全天候多学科监测和管理。在2022年9月至2023年11月期间,6家合作医院实施了远程icu,并参加了针对远程icu工作流程量身定制的间隔高级心脏生命支持(ACLS)课程。研究期间从床边ACLS培训前的三个月(“干预前”)到完成后的六个月(“干预后”)。采用多变量logistic回归和中断时间序列分析评估干预对自发循环恢复(ROSC)率和总体医院死亡率的影响。结果163例心脏骤停事件(干预前52例,干预前111例)中,发生在ICU入院5 d内的发生率最高(83.4%),最常见的诱发心律为骤停(61.3%)。与干预前(19.2%)相比,远程icu站点在干预后的ROSC率(38.7%)显著更高(调整优势比[aOR] 3.65[95%可信区间[CI] 1.40-9.53])。这相当于立即增加16.1% (95% CI 0.7% - 31.5%)的水平,而没有显著的趋势变化(- 0.10%[- 0.97% - 0.77%])。总体住院生存率相似(4.5% vs. 3.8%;(aOR 0.69 [95% CI 0.08-5.72])。结论:采用steli - icu配合有针对性的ACLS培训与院内即时心脏骤停结果的改善相关,突出了低成本、技术支持的护理交付模式在优化中低收入国家复苏表现方面的潜力。
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引用次数: 0
The digital equity paradox: When good intentions pave the road to technological stratification 数字公平悖论:当善意为技术分层铺平道路时
IF 3.7 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-07-28 DOI: 10.1016/j.hlpt.2025.101079
Y. Tony Yang
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引用次数: 0
Adverse events involving medical devices in Dutch hospitals: A patient record review study 荷兰医院中涉及医疗器械的不良事件:一项患者记录回顾研究
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-06-30 DOI: 10.1016/j.hlpt.2025.101063
Mees.C. Baartmans , Steffie.M. van Schoten , Bo Schouten , Linda van Eikenhorst , Renske M. Hoeben , Henk Asscheman , Cordula Wagner

Objectives

To report the incidence of potentially preventable Adverse Events involving a Medical Device (AEMD) and provide an overview of specific topics on how devices were involved in causing patient harm.

Methods

A retrospective nationwide patient record review study using randomly selected records of 2998 patients deceased during their admission in 20 Dutch hospitals in 2019.

Results

63 potentially preventable AEMDs were identified, corresponding to a weighted incidence of 1.9 % (95CI 1.5 %-2.5 %). Medical devices were involved in about half of all potentially preventable adverse events. Consequences for patients were often severe. Themes in how medical devices were involved in causing patient harm were: Endoscopes causing perforations and hemorrhages, bleedings and infections after placement of heart- and vascular implants, and respiratory harm related to naso- and orogastric tube application. In most cases, the role of the device in causing adverse events was that of prompting a known complication. Preventability in these cases often lied in the subsequent management of the bleeding, perforation or infection.

Conclusions

AEMDs occur in a small percentage of patients admitted and deceased in Dutch hospitals, but do represent a substantial part of all potentially preventable adverse events identified amongst the old and severely comorbid patient group in this study. An additional analysis of the data, provided a more thorough understanding of how the use of medical devices contributes to patient harm. Other study designs are necessary to learn more about technical and organizational issues that might trigger AEMDs.

Public interest summary

Most medical device applications are safe and effective. Though in a small number of cases an Adverse Event involving a Medical Device (AEMD) occurs. This study found that in 1.9 % (95CI 1.5 %-2.5 %) of patients deceased during their admission in 20 Dutch hospitals in 2019 a potentially preventable AEMD occurred. Identified topics in these AEMDs were perforations, bleedings, and infections after application of endoscopes, heart- and vascular implants, and tubes for enteral feeding or drainage. The role of the devices in these AEMDs was often that of prompting a known complication and considered non-preventable. Preventability in most cases lied in the subsequent management of the perforation, bleeding or infection.
目的报告涉及医疗器械(AEMD)的潜在可预防不良事件的发生率,并提供有关器械如何导致患者伤害的特定主题的概述。方法对荷兰20家医院2019年住院期间死亡的2998例患者进行回顾性全国病历回顾研究。结果共发现63例潜在可预防的aemd,加权发生率为1.9% (95CI为1.5% - 2.5%)。在所有可能可预防的不良事件中,约有一半涉及医疗器械。对病人造成的后果往往很严重。医疗器械如何对患者造成伤害的主题是:内窥镜引起穿孔和出血,心脏和血管植入物放置后出血和感染,以及与鼻和胃管应用有关的呼吸伤害。在大多数情况下,器械在引起不良事件中的作用是引起已知的并发症。这些病例的可预防性往往在于出血、穿孔或感染的后续处理。结论:saemd发生在荷兰医院住院和死亡患者中的比例很小,但在本研究中发现的老年和严重合并症患者组中,saemd确实代表了所有潜在可预防的不良事件的很大一部分。对数据的进一步分析使人们对医疗设备的使用如何对患者造成伤害有了更全面的了解。其他研究设计是必要的,以了解更多可能引发aemd的技术和组织问题。大多数医疗器械的应用是安全有效的。虽然在少数情况下会发生涉及医疗器械的不良事件(AEMD)。该研究发现,2019年,在20家荷兰医院住院期间死亡的患者中,有1.9% (95CI 1.5% - 2.5%)发生了潜在的可预防的AEMD。这些aemd确定的主题是应用内窥镜、心脏和血管植入物以及肠内喂养或引流管后的穿孔、出血和感染。这些设备在aemd中的作用通常是引发已知的并发症,并且被认为是不可预防的。在大多数情况下,可预防性在于对穿孔、出血或感染的后续处理。
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引用次数: 0
Rural digitalization and health outcomes of older adults in China 中国农村数字化与老年人健康状况
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-05-22 DOI: 10.1016/j.hlpt.2025.101038
Kunkun Duan , Jing Li
This study investigates the relationship between rural digitalization and older adults' health conditions. Drawing on the China Longitudinal Aging Social Survey 2020 data, using ordinary least squares (OLS) regression analysis, instrumental variable (IV) methods, and propensity score matching (PSM), the present study finds that rural digitalization significantly improves both physical health (β = 0.295, p < 0.001) and reduces depression propensity score (β = -1.540, p < 0.001). Moreover, the impact of rural digitalization development on older adults' health exhibits differences: older adults (80+) and those using the internet gain more benefits; there is more remarkable support for the physical health of less educated older adults, while mental health support is more pronounced for those with higher education levels. The findings underscore the potential of rural digitalization to mitigate health disparities and advocate for inclusive digital policies tailored to vulnerable older populations.
本研究探讨农村数字化与老年人健康状况的关系。利用《2020年中国老龄化纵向社会调查》数据,采用普通最小二乘(OLS)回归分析、工具变量(IV)方法和倾向得分匹配(PSM)方法,本研究发现农村数字化显著改善了农村居民的身体健康状况(β = 0.295, p <;0.001)并降低抑郁倾向评分(β = -1.540, p <;0.001)。此外,农村数字化发展对老年人健康的影响也存在差异:80岁以上老年人和使用互联网的老年人受益更多;受教育程度较低的老年人得到的身体健康支持更为显著,而受教育程度较高的老年人得到的心理健康支持更为明显。研究结果强调了农村数字化在缓解健康差距和倡导针对弱势老年人口的包容性数字政策方面的潜力。
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引用次数: 0
Spillover effects of pain medication tapering in chronic pain patients: a systematic review and consequences for health economic evaluation studies 慢性疼痛患者止痛药减量的溢出效应:健康经济评价研究的系统回顾和后果
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-06-02 DOI: 10.1016/j.hlpt.2025.101037
Frenn Bultinck , Nick Verhaeghe , Max Lelie , Bo Vandenbulcke , Elke Wuyts , Cleo L. Crunelle , Lisa Goudman , Maarten Moens , Koen Putman

Background

Spillover effects of pain medication tapering (PMT) programs in patients with chronic pain (CP) are underexplored. This systematic review presents current research on the study of spillover effects of PMT in patients with CP and provides suggestions for examination of spillover effects in health economic research of PMT. Understanding spillover effects enable wide-ranging assessment of interventions, including its broader impacts.

Methods

Literature was searched up to September 2023 in Web of Science, PubMed, Scopus, Embase, PsychINFO, APA PsychNet, Cochrane library, Econlit, and grey literature sources including Google Scholar, CADTH, Mednar and the WHO website. QualSyst was used for Risk of bias assessment. The study protocol was registered prospectively in PROSPERO (CRD42023461763). Results were classified into five domains and incorporated into the expanded impact inventory framework. No funding was obtained.

Results

Of 2099 records initially identified, six qualitative studies of varying quality were included. In the healthcare domain, additional demands on healthcare delivery, patients switching between healthcare providers and psychosocial impacts for healthcare providers were key findings. Scientific spillovers entailed evidence-based recommendations, enhanced PMT awareness and knowledge dissemination. Sociological effects encompassed bias affecting underrepresented groups and community-level benefits. No spillovers were found in other categories. Future research should extend beyond patient-centered outcomes to comprehensively assess PMT’s societal impact and reveal indirect benefits currently underrepresented in the literature.

Conclusions

Spillover effects of PMT in patients with CP were identified. Considering spillovers can allow policymakers to optimize healthcare policies and resource allocation in healthcare. Inclusion of only six studies is a limitation of this study.
背景:慢性疼痛(CP)患者的疼痛药物减量(PMT)计划的溢出效应尚未得到充分研究。本文系统综述了PMT对CP患者溢出效应的研究现状,并对PMT在健康经济学研究中的溢出效应研究提出了建议。了解溢出效应有助于对干预措施进行广泛评估,包括其更广泛的影响。方法在Web of Science、PubMed、Scopus、Embase、PsychINFO、APA PsychNet、Cochrane library、Econlit以及谷歌Scholar、CADTH、Mednar和WHO网站等灰色文献源中检索截至2023年9月的文献。使用QualSyst进行偏倚风险评估。该研究方案在PROSPERO中前瞻性注册(CRD42023461763)。结果被分为五个领域,并纳入扩大的影响清单框架。没有获得资金。结果在最初确定的2099份记录中,纳入了6份不同质量的定性研究。在医疗保健领域,对医疗保健服务的额外需求、患者在医疗保健提供者之间的转换以及对医疗保健提供者的心理社会影响是主要发现。科学溢出效应包括基于证据的建议、加强对PMT的认识和知识传播。社会学效应包括影响代表性不足群体和社区层面利益的偏见。其他类别没有发现溢出效应。未来的研究应超越以患者为中心的结果,全面评估PMT的社会影响,并揭示目前文献中未充分代表的间接益处。结论PMT在CP患者中的外溢效应是明确的。考虑溢出效应可以使决策者优化医疗保健政策和医疗保健资源配置。仅纳入6项研究是本研究的局限性。
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引用次数: 0
The effectiveness of mobile health applications on the quality of life of hypertension patients: A systematic review and meta-analysis 移动健康应用程序对高血压患者生活质量的影响:系统回顾和荟萃分析
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-07-03 DOI: 10.1016/j.hlpt.2025.101064
Nouran Hamza , Wael Hafez , Sara Adel Abdelkader Saed , Marina Raouf , Nesma Magdi , Sahar Allam , Rahma Sweedy , Dina Alaraby , Marwa Muhammed Abdeljawad , Nouran A. Taha

Background

The complexity and burden of hypertension management necessitate innovative strategies to improve care quality and patient outcomes. Our meta-analysis aimed to evaluate the impact of e-health interventions on hypertension patients' quality of life and medication adherence.

Methods

A systematic review and meta-analysis were conducted using medical electronic databases for literature published before June 30, 2023. Studies investigating the efficacy of mobile health applications on the quality of life of hypertension patients were included. We extracted the studies’ characteristics, patient descriptions, and efficacy outcomes of mobile health applications. Quality assessment was done using ROB 2 and ROBINS-I V2. A meta-analysis was conducted using RevMan software.

Results

The intervention significantly decreased the standardized mean difference of the systolic blood pressure (SBP) measures compared to the control (SMD=-0.43; 95 % CI= -0.52, -0.17; p < 0.01). Additionally, it significantly increased the odds of blood pressure control (OR=3.05; 95 %CI=1.42, 6.54; p < 0.01). The heterogeneity was high; therefore, sensitivity and subgroup analyses were conducted: The intervention significantly increased the quality of life score of hypertension patients compared to the control (SMD=0.19; 95 % CI=0.04, 0.33; p = 0.01). It also significantly decreased the SMD of the SBP change from baseline and the diastolic blood pressure change from baseline compared to the control [(SMD=-4.29; 95 % CI= -5.05, -3.52; p < 0.01), (SMD=-2.75; 95 % CI= -4.06, -1.45; p < 0.01), respectively].

Conclusion

Our study demonstrates the efficacy of e-health interventions in promoting hypertension self-management, highlighting their potential as a scalable and accessible tool among the mobile phone-using population.

Public Interest Summary

Hypertension is a serious disease with severe complications if left uncontrolled. Our goal was to collect all available data on using mobile health applications in hypertension patients to facilitate their medication adherence and thus improve their quality of life. Our results show a noticeable enhancement in blood pressure control and increased patients’ quality of life after using these mobile health applications. This synthesized evidence can help patients and their healthcare providers recognize the strong efficacy and promising outcomes of these applications across multiple studies, which can ultimately lead to widespread utilization and more benefits to patients.
背景:高血压管理的复杂性和负担需要创新策略来提高护理质量和患者预后。我们的荟萃分析旨在评估电子健康干预对高血压患者生活质量和药物依从性的影响。方法利用医学电子数据库对2023年6月30日前发表的文献进行系统评价和meta分析。包括调查移动健康应用程序对高血压患者生活质量的疗效的研究。我们提取了这些研究的特征、患者描述和移动医疗应用程序的疗效结果。采用rob2和ROBINS-I V2进行质量评价。采用RevMan软件进行meta分析。结果与对照组相比,干预显著降低了收缩压(SBP)测量的标准化平均差(SMD=-0.43;95% ci = -0.52, -0.17;p & lt;0.01)。此外,它显著增加血压控制的几率(OR=3.05;95% ci =1.42, 6.54;p & lt;0.01)。异质性高;因此,进行敏感性和亚组分析:干预组高血压患者的生活质量评分较对照组显著提高(SMD=0.19;95% ci =0.04, 0.33;P = 0.01)。与对照组相比,它还显著降低了收缩压变化的SMD值和舒张压变化的SMD值[(SMD=-4.29;95% ci = -5.05, -3.52;p & lt;0.01), (SMD = -2.75;95% ci = -4.06, -1.45;p & lt;0.01),分别)。结论:我们的研究证明了电子健康干预在促进高血压自我管理方面的有效性,强调了它们在使用手机的人群中作为一种可扩展和可获得的工具的潜力。高血压是一种严重的疾病,如果不加以控制,会有严重的并发症。我们的目标是收集关于高血压患者使用移动健康应用程序的所有可用数据,以促进他们的药物依从性,从而提高他们的生活质量。我们的研究结果显示,在使用这些移动健康应用程序后,血压控制明显增强,患者的生活质量也有所提高。这些综合证据可以帮助患者及其医疗保健提供者在多个研究中认识到这些应用程序的强大功效和有希望的结果,从而最终导致广泛使用并为患者带来更多益处。
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引用次数: 0
Lowering inequality in access to emergency contraception: The effect of a Chilean public policy 降低获得紧急避孕方面的不平等:智利一项公共政策的影响
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-06-28 DOI: 10.1016/j.hlpt.2025.101066
Sebastián Lavanderos , Andrea Morales , Camilo Riquelme , Juan Haase

Objectives

To evaluate the impact of legal changes, specifically Law 20.418, on reducing inequality in emergency contraception (EC) access in Chile between 2008 and 2013.

Methods

A longitudinal, retrospective analysis was conducted using data from the Monthly Statistical Record (REM) of the Chilean Ministry of Health. EC consultation rates were calculated for ambulatory and total consultations, including rape-related cases, across communes. Inequality was assessed using Lorenz curves and four inequality indicators: Gini index, Theil index, coefficient of variation, and 75/25 ratio.

Results

The study found a significant reduction in communal inequality in EC consultations after the implementation of Law 20.418 in 2010. Between 2008 and 2013, the Gini index for ambulatory consultations decreased by 41 %, while for total consultations, it dropped by 20 %. Other inequality indicators also showed substantial decreases, with the 75/25 ratio decreasing by 73 % for ambulatory consultations. Regional analysis revealed a consistent downward trend in inequality, with the most significant improvements occurring in areas with higher consultation rates.

Conclusions

The findings indicate that the legal reforms introduced by Law 20.418 contributed to reducing disparities in EC access across communes. Despite improvements, some residual inequalities persist, highlighting the need for further research to identify and address remaining barriers to equitable EC access in certain regions.

Lay Summary

This study evaluates the impact of Chile's Law 20.418, which mandated the provision of emergency contraception (EC) in the public health system, on reducing access inequality. Data from 2008 to 2013 show a significant decrease in inequality in EC consultations across communes. The Gini index and other inequality indicators revealed improvements, with a 41 % reduction in inequality for ambulatory consultations and a 20 % reduction for total consultations. These changes are linked to the law's implementation, which expanded EC access, particularly in rural and underserved areas. Despite the progress, some disparities remain, suggesting that while policy interventions have made access more equitable, further efforts are needed to address residual barriers. This study highlights the importance of legal frameworks in promoting health equity, particularly in reproductive healthcare.
目的评估2008年至2013年期间智利法律变化,特别是第20.418号法律对减少紧急避孕(EC)获取不平等的影响。方法采用智利卫生部每月统计记录(REM)资料进行纵向、回顾性分析。计算了各社区的门诊和总会诊率,包括与强奸有关的案件。采用Lorenz曲线和四个不平等指标:基尼指数、Theil指数、变异系数和75/25比率来评估不平等。研究发现,2010年第20.418号法律实施后,欧共体咨询中的社区不平等现象显著减少。2008年至2013年间,门诊咨询的基尼系数下降了41%,而总咨询的基尼系数下降了20%。其他不平等指标也大幅下降,门诊咨询的75/25比率下降了73%。区域分析显示,不平等现象呈持续下降趋势,在咨询率较高的地区改善最为显著。研究结果表明,第20.418号法律引入的法律改革有助于减少各社区在获取欧共体方面的差距。尽管有所改善,但仍然存在一些不平等现象,突出表明需要进一步研究,以确定和解决某些区域公平获得欧共体的仍然存在的障碍。本研究评估了智利第20.418号法律的影响,该法律规定在公共卫生系统中提供紧急避孕(EC),以减少获取不平等。2008年至2013年的数据显示,各社区的欧共体咨询不平等现象显著减少。基尼指数和其他不平等指标显示出改善,门诊不平等减少了41%,总咨询减少了20%。这些变化与该法的实施有关,该法扩大了电子商务的使用范围,特别是在农村和服务不足的地区。尽管取得了进展,但仍然存在一些差距,这表明虽然政策干预使获得机会更加公平,但需要进一步努力解决剩余的障碍。这项研究强调了法律框架在促进健康公平方面的重要性,特别是在生殖保健方面。
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引用次数: 0
Benefits and challenges of high-density microarray patches for vaccination among older adults: A qualitative study 老年人接种高密度微阵列贴片的益处和挑战:一项定性研究
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-07-01 DOI: 10.1016/j.hlpt.2025.101065
Matthew N. Berger , Sara L. Knox , Ben Baker , Benjamin G. Stewart , Charles Ross , Erin Mathieu , Angus H. Forster , S.Rachel Skinner , Cristyn Davies

Objectives

Microarray Patches (MAPs) deliver vaccines to the upper dermis and epidermis, rich in immune cells. This study explored the perceived safety, usability, and acceptability of High-Density Microarray Patches (HD-MAPs) among older adults aged 50+.

Methods

This was a single-centre, single-arm, open-label study using excipient-coated HD-MAPs. A trained user administered two HD-MAPs to each participant’s dominant arm, and participants self-administered to their non-dominant arm. Semi-structured interviews were conducted on days 0 and 28. Thematic analysis was used to explore participant experiences.

Results

Forty-four older adults were recruited. Themes explored the benefits and challenges of HD-MAPs. Benefits included (1) mass distribution and administration, (2) reduced healthcare burden, and (3) convenience, particularly in low-resource settings due to thermostability and potential for self-administration. Participants felt that use of trained users and self-administration could reduce burden on healthcare resources. Challenges highlighted were (1) safety of unsupervised use, (2) proof of vaccination, and (3) user confidence and cost. Concerns about adverse events and correct dosage were raised, though participants felt reassured by the sensation, applicator sound, and mark after application.

Conclusion

HD-MAPs may ease healthcare burdens and improve convenience and acceptability among older adults, offering an alternative to needles and syringes, especially for vulnerable populations.

Lay summary

This study explored how older adults (aged 50+) perceived the safety, usability, and acceptability of High-Density Microarray Patches (HD-MAPs), a new, needle-free vaccine delivery method. Participants received the HD-MAP from a trained user and also tried self-administering it. Most found HD-MAPs convenient and easy to use, appreciating their potential for home use and application in remote areas without refrigeration. Participants liked the idea of reducing the burden on healthcare systems and found the HD-MAPs less intimidating than needles. However, some concerns were raised, including safety when used unsupervised, confirming successful vaccine delivery, and cost. Participants suggested using telehealth or supervised settings to enhance confidence. Overall, HD-MAPs were considered a promising vaccination alternative, especially during pandemics and in low-resource settings. The technology may help increase vaccination rates in older adults by offering more accessible, less painful options.
目的微阵列贴片(microarray Patches, MAPs)将疫苗递送到富含免疫细胞的上真皮层和表皮。本研究探讨了高密度微阵列贴片(HD-MAPs)在50岁以上老年人中的感知安全性、可用性和可接受性。方法这是一项单中心、单臂、开放标签的研究,使用辅料包被的HD-MAPs。一名训练有素的使用者给每个参与者的优势手臂注射两张hd - map,参与者自己给他们的非优势手臂注射hd - map。半结构化访谈在第0天和第28天进行。主题分析用于探讨参与者体验。结果共招募了44名老年人。主题探讨了高清地图的好处和挑战。好处包括:(1)大规模分发和管理,(2)减轻医疗负担,以及(3)便利,特别是在资源匮乏的环境中,由于热稳定性和自我管理的潜力。与会者认为,使用经过培训的用户和自我管理可以减轻保健资源的负担。突出的挑战是(1)无监督使用的安全性,(2)疫苗接种证明,(3)用户信心和成本。对不良事件和正确剂量的担忧增加了,尽管参与者对感觉、涂抹器声音和涂抹后的标记感到放心。结论hd - maps可减轻老年人的医疗负担,提高老年人的便利性和可接受性,为老年人特别是弱势群体提供针头和注射器的替代选择。本研究探讨了老年人(50岁以上)对高密度微阵列贴片(HD-MAPs)的安全性、可用性和可接受性的看法,高密度微阵列贴片是一种新的、无针疫苗递送方法。参与者从训练有素的用户那里获得HD-MAP,并尝试自我管理。大多数人认为HD-MAPs方便易用,赞赏其在家庭使用和在没有制冷的偏远地区的应用潜力。与会者喜欢减轻卫生保健系统负担的想法,并发现高清地图不像针头那么令人生畏。然而,提出了一些关切,包括在无监督情况下使用的安全性、确认疫苗交付成功以及成本。与会者建议使用远程保健或有监督的环境来增强信心。总体而言,HD-MAPs被认为是一种有希望的疫苗接种替代方案,特别是在大流行期间和资源匮乏的环境中。这项技术可以提供更方便、更少痛苦的选择,从而有助于提高老年人的疫苗接种率。
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引用次数: 0
Dynamic decision system for ENT surgery waiting list prioritization using M-Score and TOPSIS methodology 基于M-Score和TOPSIS方法的耳鼻喉外科候诊名单优先排序动态决策系统
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-06-03 DOI: 10.1016/j.hlpt.2025.101036
Fabián Silva-Aravena, Jenny Morales
Objective: This study aims to develop and evaluate a dynamic prioritization system to improve surgical waiting list management for otorhinolaryngology (ENT) patients in a high-complexity public hospital in Chile. The proposed model aims to reduce waiting times and improve equity and clinical outcomes by dynamically incorporating changes in patient condition. Methods: We implemented a dynamic scoring system (M-Score), updated weekly using multidimensional biopsychosocial criteria, and integrated it with the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) to prioritize patients. The evaluation was carried out using Monte Carlo simulations over a 52-week horizon, simulating patient inflows and outflows via a balanced flow model. The stability and performance of the proposed model were compared with a static model and a traditional first-come, first-served (FCFS) protocol. Results: The proposed approach reduced the average waiting time from 130 to 91 days compared to the static model (a 30 % relative and absolute decrease of 39 days) and from 157 to 91 days compared to FCFS (a 42 % relative and absolute reduction of 66 days). The greatest improvements were observed among high-risk patients, whose prioritization was adapted in real time to worsening clinical conditions. Conclusions: Our adaptive prioritization model demonstrates significant improvements in waiting time management, particularly for clinically vulnerable patients. Although the findings support its feasibility, further prospective validation is necessary before clinical implementation. Future research should focus on real-time integration with electronic medical records, scalability between specialties, and evaluation of impacts on patient satisfaction and health outcomes. Lay Summary: ENT patients in public hospitals often face long waiting times that increase health risks. This study introduces a weekly update to the prioritization model using social and health factors of the patient. The system reduced average waiting times by up to 66 days in simulation. High-risk patients were prioritized as their conditions worsened. This approach offers a promising data-driven strategy for improving waitlist management and resource allocation in public healthcare.
目的:本研究旨在开发和评估动态优先排序系统,以改善智利一家高复杂性公立医院耳鼻喉科(ENT)患者的手术等待名单管理。提出的模型旨在通过动态结合患者病情的变化来减少等待时间,提高公平性和临床结果。方法:我们实施了一个动态评分系统(M-Score),每周更新一次,使用多维生物心理社会标准,并将其与理想解决方案相似性排序偏好技术(TOPSIS)相结合,对患者进行优先排序。评估使用蒙特卡罗模拟进行,为期52周,通过平衡流动模型模拟患者流入和流出。将该模型的稳定性和性能与静态模型和传统的先到先服务(FCFS)协议进行了比较。结果:与静态模型相比,该方法将平均等待时间从130天减少到91天(相对和绝对减少39天,减少30%),与FCFS相比,该方法将平均等待时间从157天减少到91天(相对和绝对减少66天,减少42%)。在高危患者中观察到最大的改善,他们的优先级实时适应恶化的临床状况。结论:我们的适应性优先排序模型显示了等待时间管理的显著改善,特别是对临床弱势患者。尽管研究结果支持其可行性,但在临床应用之前需要进一步的前瞻性验证。未来的研究应集中在与电子病历的实时集成、专科之间的可扩展性以及对患者满意度和健康结果影响的评估上。概要:公立医院的耳鼻喉科病人经常面临长时间的等待,这增加了健康风险。这项研究引入了每周更新的优先级模型,使用患者的社会和健康因素。在模拟中,该系统将平均等待时间缩短了66天。随着病情恶化,高危患者被优先考虑。这种方法为改善公共医疗保健的候补名单管理和资源分配提供了一种有前途的数据驱动策略。
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引用次数: 0
How has Aggregated Mobility Data-informed public health research? 综合流动数据如何为公共卫生研究提供信息?
IF 3.4 3区 医学 Q1 HEALTH POLICY & SERVICES Pub Date : 2025-09-01 Epub Date: 2025-06-08 DOI: 10.1016/j.hlpt.2025.101055
Jennifer Turnnidge , Oluwatoyosi Kuforiji , Sina Sayyad , Sarah Greco , Sawmmiya Kirupaharan , Angélique Roy , Nancy Dalgarno , Angel Zhou , Mir Sanim Al Mamun , Hiroshi Mamiya , Khai Hoan Tram , Sahar Saeed

Objective

The widespread adoption of smartphones has enabled the collection and analysis of population-level mobility patterns through Aggregated Mobility Data. This type of data, which is derived from both operator and crowdsourced sources, presents opportunities and challenges for public health research. This data derived from both operator and crowdsourced sources, presents opportunities and challenges for public health research. We explore how this novel data source has been used in public health studies, its benefits, limitations, and ethical considerations.

Methods

We conducted a narrative review of Aggregated Mobility Data applications in public health research, critically examining its potential and challenges. A systematic search of Embase and Google Scholar identified 645 peer-reviewed primary research articles. We included English peer-reviewed and primary research published between 2010–2024 where aggregated mobility data was being used to evaluate a public health outcome. After applying inclusion criteria, 95 studies were included for narrative synthesis and descriptive quantitative analysis.

Results

We found the majority of studies to date using Aggregated Mobility Data were related to COVID-19. Reporting of ethical and privacy considerations varied widely, with some studies undergoing formal ethics review and others citing exemptions based on the use of anonymized or aggregate data. Key limitations of Aggregated Mobility Data included restricted access to data sources and challenges associated with small population sizes.

Conclusion

This review underscores the potential of Aggregated Mobility Data in public health research and highlights key considerations for researchers and policymakers. Future studies should address ethical standardization, data accessibility, and broader applications beyond infectious disease surveillance to fully leverage the utility of Aggregated Mobility Data in public health decision-making.

Public Interest Summary

With the rise of smartphones, researchers can now track population movement using Aggregated Mobility Data from mobile devices. This data has been widely used in public health, especially during COVID-19, to understand how people move and how that impacts disease spread. However, access to this data is often restricted, and ethical considerations like privacy protections vary across studies. Our review examined 95 studies to assess the applications in public health research. While this data offers valuable insights, future research should focus on standardizing ethical guidelines, improving data access, and expanding its use beyond infectious disease tracking to other public health challenges.
智能手机的广泛采用使得通过汇总移动数据收集和分析人口水平的移动模式成为可能。这类数据来自运营商和众包来源,为公共卫生研究带来了机遇和挑战。这些数据来自运营商和众包来源,为公共卫生研究带来了机遇和挑战。我们将探讨这种新的数据来源是如何在公共卫生研究中使用的,它的益处、局限性和伦理考虑。方法:我们对汇总移动数据在公共卫生研究中的应用进行了叙述性回顾,批判性地考察了其潜力和挑战。对Embase和b谷歌Scholar的系统搜索确定了645篇同行评议的初级研究文章。我们纳入了2010-2024年间发表的英语同行评议和初级研究,这些研究使用了汇总的流动性数据来评估公共卫生结果。应用纳入标准,纳入95项研究进行叙事综合和描述性定量分析。结果我们发现,迄今为止使用汇总流动性数据的大多数研究都与COVID-19有关。关于伦理和隐私考虑的报告差异很大,一些研究经过了正式的伦理审查,而另一些研究则基于使用匿名或汇总数据而获得豁免。汇总流动数据的主要限制包括对数据源的访问受限以及与人口规模小相关的挑战。结论:本综述强调了汇总流动数据在公共卫生研究中的潜力,并强调了研究人员和政策制定者需要考虑的关键因素。未来的研究应解决伦理标准化、数据可及性以及传染病监测以外的更广泛应用,以充分利用聚合流动性数据在公共卫生决策中的效用。随着智能手机的兴起,研究人员现在可以使用来自移动设备的汇总移动数据来跟踪人口流动。这些数据已被广泛用于公共卫生领域,特别是在COVID-19期间,以了解人们如何移动以及如何影响疾病传播。然而,对这些数据的访问往往受到限制,隐私保护等伦理考虑在不同的研究中有所不同。我们回顾了95项研究,以评估其在公共卫生研究中的应用。虽然这些数据提供了有价值的见解,但未来的研究应侧重于规范伦理准则,改善数据获取,并将其应用范围从传染病追踪扩展到其他公共卫生挑战。
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引用次数: 0
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Health Policy and Technology
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