Ticks and Tick-borne Diseases最新文献

英文中文

Incidental infestations of humans by hard ticks (Acari: Ixodidae) in Colombia: Case reports and record of Amblyomma cajennense sensu stricto 哥伦比亚硬蜱（蜱螨：伊蚊科）对人类的偶发侵害：严格卡詹氏弱视虫病例报告和记录。

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-11-01 DOI: 10.1016/j.ttbdis.2025.102565

Omar Esteban Vargas-Martínez , Luisa Fernanda Naranjo-Vargas , Laura Aramendiz-Macías , Francisco J. Díaz , Juan Carlos Quintero-Vélez , Thiago Fernandes Martins , Juan David Rodas-González

In Colombia, there are few studies that describe tick parasitism in humans, as well as its demographic and ecological characteristics. Additionally, multiple cases of human rickettsiosis caused by highly pathogenic Rickettsia species have been reported, whose vector remains unknown. This study reports new cases of human infestation by hard ticks in rural areas of different municipalities of Colombia between 2021 and 2023. The collected ticks were identified using taxonomic keys and molecular and phylogenetic analyses. Likewise, geographical data and other variables associated with parasitism were recorded. A total of 17 hard ticks were collected, associated with 15 infestation cases from nine individuals in eight municipalities across four departments of Colombia. Our findings included infestations by Amblyomma cajennense sensu stricto [s.s.] in the department of Meta, a species never reported in Colombia, and Amblyomma oblongoguttatum in Antioquia, not reported in humans since 1949. We also report cases of human parasitism by Amblyomma mixtum, Dermacentor nitens, and Rhipicephalus microplus. No Rickettsia bacteria were detected in the ticks. This study highlights the importance of recording the interaction of these ectoparasites with humans in Colombia, expanding knowledge about the diversity of tick species and their parasitic activity in our country.

在哥伦比亚，很少有研究描述蜱寄生在人类身上，以及它的人口和生态特征。此外，已报告了由高致病性立克次体物种引起的多例人类立克次体病，其媒介仍然未知。本研究报告了2021年至2023年期间哥伦比亚不同城市农村地区硬蜱感染人类的新病例。收集到的蜱虫通过分类键、分子和系统发育分析进行鉴定。同样，还记录了地理数据和其他与寄生有关的变量。共收集到17只硬蜱，与来自哥伦比亚4个省8个城市9个人的15例感染病例有关。我们的发现包括卡延氏狭义弱视瘤（Amblyomma cajenense sensu stricto）的侵染。]，这是一种在哥伦比亚从未报道过的物种，以及安蒂奥基亚的长形双足虫，自1949年以来没有在人类身上报道过。我们也报告了混合弱视虫、黑皮肤螨和微型鼻头虫的病例。蜱中未检出立克次体细菌。这项研究强调了在哥伦比亚记录这些体外寄生虫与人类相互作用的重要性，扩大了对我国蜱类物种多样性及其寄生活动的认识。

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引用次数: 0

UB-221, an antibody that neutralizes IgE and downregulates the CD23 receptor: a potential treatment for the alpha-gal syndrome UB-221，一种中和IgE并下调CD23受体的抗体：一种治疗α -半乳糖综合征的潜在方法。

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-11-01 DOI: 10.1016/j.ttbdis.2025.102562

Sandra E. Reznik , Amit K. Tiwari , Charles R. Ashby Jr.

引用次数: 0

Tick responses to diverse chemical attractants to enhance tick surveillance methods’ efficacy 蜱对不同化学引诱剂的反应，提高蜱监测方法的有效性

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-11-01 DOI: 10.1016/j.ttbdis.2025.102577

Pamela Kelman , Tyler Chavers , Emily Owens Pickle , Daniel Sonenshine , Melissa S Nolan , Holly Gaff

Amblyomma maculatum Koch (Acari: Ixodidae), Ixodes scapularis Say, and Dermacentor variabilis Say are three hard-bodied ticks responsible for vectoring pathogens that cause most human tick-borne diseases in the United States of America (USA). Tick surveillance is critical to elucidate high-risk areas for targeted vector control and public health interventions. Despite tick-borne diseases having a higher annual incidence compared to mosquito-borne diseases in the USA, tick traps used for surveillance are grossly under-developed compared to the suite of sophisticated mosquito traps available on the commercial market. This study sought to identify potential prospective tick trap improvements by evaluating the relative attraction of three medically important tick species to odor attractants in a laboratory setting: carbon dioxide, ammonia, deer musk, and rodent musk. This study found that carbon dioxide gas and rodent musk had limited attraction to all three tick species and across life stages. Conversely, this study did find that deer musk and ammonia demonstrated favorable attraction for I. scapularis and D. variabilis across multiple life stages, suggesting standard tick trap techniques might be improved using low-cost and practical alternate attractants. Future field-based studies of these odor attractants, both singularly and in combination with the standard dry ice, are warranted to evaluate potential increased efficacy for broad tick species vector surveillance methods.

斑点无眼蜱（蜱螨目：硬蜱科）、肩胛骨硬蜱和变皮蜱是三种硬体蜱，负责传播导致美国大多数人类蜱媒疾病的病原体。蜱虫监测对于阐明有针对性的媒介控制和公共卫生干预的高风险地区至关重要。尽管在美国，蜱传疾病的年发病率高于蚊传疾病，但与商业市场上可获得的一套复杂的蚊子陷阱相比，用于监测的蜱虫陷阱严重欠发达。本研究试图通过在实验室环境中评估三种医学上重要的蜱类对气味引诱剂的相对吸引力，即二氧化碳、氨、鹿麝香和啮齿动物麝香，来确定潜在的潜在蜱虫诱捕器的改进。这项研究发现，二氧化碳气体和啮齿动物麝香对所有三种蜱虫的吸引力有限，而且在生命的各个阶段都是如此。相反，本研究确实发现，鹿麝香和氨水在多个生命阶段对肩胛骨夜蛾和变异夜蛾具有良好的吸引力，这表明使用低成本和实用的替代引诱剂可以改进标准的蜱虫诱捕技术。未来对这些气味引诱剂的实地研究，无论是单独使用还是与标准干冰结合使用，都有必要评估广泛蜱虫媒介监测方法可能增加的效果。

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引用次数: 0

Corrigendum to “First molecular detection of Anaplasma marginale, Babesia bovis, and hemotropic Mycoplasma spp. in bovine colostrum” [Ticks and Tick-borne Diseases 16 (2025) 102553] “牛初乳中边缘无原体、牛巴贝斯虫和嗜血支原体的首次分子检测”[蜱和蜱传疾病16(2025)102553]的勘误表。

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-11-01 DOI: 10.1016/j.ttbdis.2025.102564

Mayara Campos Lombardi , Nicolas Colacio , Camila de Valgas e Bastos , Sandra Gesteira Coelho , Tiago Facury Moreira , Rodrigo Melo Meneses , Antônio Último de Carvalho , Elias Jorge Facury-Filho , Júlia Angelica Gonçalves Silveira

引用次数: 0

Corrigendum to “Various small mammal hosts are involved in the transmission cycle of zoonotic Anaplasma phagocytophilum in Southeastern Canada” [Ticks and Tick-borne Diseases (2025) Volume 16, Issue 6] “各种小型哺乳动物宿主参与加拿大东南部人畜共患病嗜吞噬细胞无原体的传播周期”[蜱和蜱传疾病（2025）第16卷，第6期]的更正。

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-11-01 DOI: 10.1016/j.ttbdis.2025.102563

Raphaëlle Audet-Legault , Cécile Aenishaenslin , Geneviève Baron , Heather Coatsworth , Marion Desmarchelier , Vanessa Gabriele-Rivet , Patrick A․ Leighton , Jérôme Pelletier , Jean-Philippe Rocheleau , Catherine Bouchard

引用次数: 0

Quantitative proteomic analysis of salivary glands in female Ornithodoros lahorensis (syn. Alveonasus lahorensis) after blood feeding via DIA-coupled LC-MS/MS 利用双级联LC-MS/MS对雌性拉霍伦鸟（Ornithodoros lahorensis，同音：Alveonasus lahorensis）供血后唾液腺的定量蛋白质组学分析

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-11-01 DOI: 10.1016/j.ttbdis.2025.102575

Xiangfen Yuan , Xiaolin Xu , Huiyu Wang , Hongli Jing , Songyin Qiu , Yufang Kong , Yue Zhang , Jizhou Lv , Xun Suo , Shaoqiang Wu

Ornithodoros lahorensis (syn. Alveonasus lahorensis) is a species of soft tick within the Argasidae family, known for causing debilitating symptoms, as well as transmitting pathogens that pose significant health risks and economic losses to affected livestock and potentially humans. The salivary gland is the key component in the pathogenic mechanisms of ticks, as it not only facilitates feeding but also serves as a medium for pathogen transmission. Here, data-independent acquisition (DIA) coupled to liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used to quantitatively identify differentially expressed proteins (DEPs) in female O. lahorensis salivary glands after blood feeding. A total of 3866 proteins were annotated, and 1185 DEPs were identified at 24 h post-feeding (1105 upregulated, 80 downregulated). The data are available via ProteomeXchange with identifier PXD059319. Bioinformatics analyses revealed that these DEPs are primarily involved in metabolic processes, immune regulation, ribosomal assembly, and signal transduction. This study provides the first comprehensive analysis of the O. lahorensis salivary glands proteomes during the early post-feeding period, offering valuable insights for future research on and control ticks and tick-borne diseases.

lahorensis（同：Alveonasus lahorensis）是一种软蜱，属于松毛虫科，以引起衰弱症状和传播病原体而闻名，对受影响的牲畜和潜在的人类造成重大健康风险和经济损失。唾液腺是蜱的致病机制的关键组成部分，因为它不仅促进了摄食，而且是病原体传播的媒介。本研究采用数据独立采集（DIA）与液相色谱-串联质谱（LC-MS/MS）相结合的方法，定量鉴定了吸血后雌拉荷莲唾液腺中的差异表达蛋白（DEPs）。共注释了3866个蛋白，在喂食后24 h鉴定出1185个dep（1105个上调，80个下调）。数据可通过ProteomeXchange获得，标识符为PXD059319。生物信息学分析显示，这些dep主要参与代谢过程、免疫调节、核糖体组装和信号转导。本研究首次全面分析了吸血后早期lahorensis的唾液腺蛋白质组，为今后研究和控制蜱和蜱传疾病提供了有价值的见解。

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引用次数: 0

Gagosa Mountain virus, a novel arbovirus identified in Ornithodoros lahorensis ticks from the Shigatse region of the Tibetan Plateau

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-11-01 DOI: 10.1016/j.ttbdis.2025.102571

Yingxin Tu , Can Wang , Wenbing Zhu , Tajie Danba , Shuo Feng , Meixi Ren , Guoyu Niu , Yujing Zhu

Ticks are the second most important vectors of human diseases after mosquitoes. Hard ticks are more abundant and widespread than soft ticks, resulting in their greater involvement in diverse diseases. Consequently, most research on tick-borne pathogens has focused on hard ticks. In contrast, soft ticks, which comprise fewer species, have received less research attention. In this study, we identified a novel single-stranded RNA virus (tentatively named Gagosa Mountain virus) in Ornithodoros lahorensis ticks from the Shigatse region of Tibet. We collected 80 engorged soft ticks from Tibetan sheep, placing each in a separate tube for pathogen analysis. Quantitative real-time PCR (qRT-PCR) and nested PCR techniques were employed to confirm the presence of Gagosa Mountain virus, and subsequent analyses focused on elucidating its genomic features and phylogenetic relationships. Our results demonstrated that Gagosa Mountain virus was present in 15 out of 80 ticks, corresponding to a positivity rate of 19%. The 13,133-nucleotide single-stranded negative-sense RNA genome contained six open reading frames (ORFs) encoding the N protein, RdRp, and four hypothetical proteins. Pairwise distance analysis showed high nucleotide sequence identity among the viral sequences. Phylogenetic analysis indicated that Gagosa Mountain virus is most closely related to Lhasa Rhabd tick virus 1, which is an unclassified member of the family Rhabdoviridae. Further analyses demonstrated that Gagosa Mountain virus represents a novel member of the genus Betanemrhavirus within the family Rhabdoviridae.

蜱虫是仅次于蚊子的第二大人类疾病传播媒介。硬蜱比软蜱更丰富和广泛，导致它们更多地参与各种疾病。因此，大多数关于蜱传病原体的研究都集中在硬蜱上。相比之下，种类较少的软蜱受到的研究关注较少。采用实时荧光定量PCR （qRT-PCR）和巢式PCR技术证实了Gagosa Mountain病毒的存在，随后的分析重点是阐明其基因组特征和系统发育关系。结果表明，80只蜱中有15只存在加戈萨山病毒，阳性率为19%。13133个核苷酸的单链负义RNA基因组包含6个开放阅读框（orf），编码N蛋白、RdRp和4个假设蛋白。两两距离分析显示病毒序列具有较高的核苷酸序列一致性。系统发育分析表明，该病毒与拉萨蜱病毒1型亲缘关系最密切，为弹状病毒科未分类成员。进一步分析表明，Gagosa Mountain病毒是横纹病病毒科Betanemrhavirus属的一个新成员。

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引用次数: 0

From import to establishment? Experimental evidence for seasonal outdoor survival of two Rhipicephalus species in Germany 从进口到建立？德国两种鼻头蝇季节性室外生存的实验证据

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-10-24 DOI: 10.1016/j.ttbdis.2025.102560

K. Fachet-Lehmann, A. Lindau, U. Mackenstedt

The brown dog tick (Rhipicephalus sanguineus s.l.), though not endemic in Germany, is regularly introduced via travelers with dogs and imported rescue dogs. Due to its relevance in veterinary and human medicine, its potential to establish in Germany’s climate is of interest. Although previous studies confirm indoor survival and reproduction of R. sanguineus s.s. in Germany, climate change and milder winters may also allow outdoor survival. This study assessed the survival of R. sanguineus s.s. and R. innaei from February 2023 to May 2024 using laboratory-bred ticks placed at indoor and outdoor sites. Tick survival (adults, nymphs, larvae) was monitored weekly, along with temperature and humidity. Reproductive success was evaluated via oviposition and larval hatching.

R. sanguineus s.s. adults survived up to 44 weeks, nymphs up to 20 weeks, and larvae up to 5 weeks. R. innaei showed shorter survival (37, 10, and 4 weeks, respectively). Successful oviposition and larval hatching occurred outdoors between May´23 and September´23 for both species. However, winter survival was not observed; all ticks died following sub-zero temperatures in December´23.

Despite the inability to overwinter outdoors, both species can survive for extended periods in spring and summer and may enter homes via dogs, where conditions favor year-round survival. Their ability to transition indoors via dogs, where conditions favor year-round survival, suggests a potential for establishment in Germany through combined indoor and seasonal outdoor persistence.

棕色狗蜱（嗜血根头蜱s.l）虽然在德国不是地方病，但经常通过带狗和进口救援犬的旅行者传播。由于其与兽医和人类医学的相关性，其在德国气候下建立的潜力令人感兴趣。虽然先前的研究证实了德国血鼠的室内生存和繁殖，但气候变化和温和的冬季也可能允许室外生存。本研究于2023年2月至2024年5月在室内和室外场所分别放置实验室培养的蜱，评估了血蜱和银蜱的存活情况。每周监测蜱存活情况（成虫、若虫、幼虫），同时监测温度和湿度。通过产卵和幼虫孵化来评价繁殖成功率。成虫可存活44周，若虫可存活20周，幼虫可存活5周。成活率较短，分别为37周、10周和4周。在5月23日至9月23日期间，这两个物种都在室外成功产卵和幼虫孵化。然而，没有观察到冬季存活率；所有蜱虫都在2013年12月气温降至零度以下后死亡。尽管不能在户外过冬，但这两个物种都可以在春夏两季存活很长一段时间，并可能通过狗进入家庭，那里的环境有利于全年生存。他们通过狗过渡到室内的能力，那里的条件有利于全年生存，这表明通过室内和季节性室外持久性结合在德国建立的潜力。

{"title":"From import to establishment? Experimental evidence for seasonal outdoor survival of two Rhipicephalus species in Germany","authors":"K. Fachet-Lehmann, A. Lindau, U. Mackenstedt","doi":"10.1016/j.ttbdis.2025.102560","DOIUrl":"10.1016/j.ttbdis.2025.102560","url":null,"abstract":"<div><div>The brown dog tick (<em>Rhipicephalus sanguineus</em> s.l.), though not endemic in Germany, is regularly introduced via travelers with dogs and imported rescue dogs. Due to its relevance in veterinary and human medicine, its potential to establish in Germany’s climate is of interest. Although previous studies confirm indoor survival and reproduction of <em>R. sanguineus</em> s.s. in Germany, climate change and milder winters may also allow outdoor survival. This study assessed the survival of <em>R. sanguineus</em> s.s. and <em>R. innaei</em> from February 2023 to May 2024 using laboratory-bred ticks placed at indoor and outdoor sites. Tick survival (adults, nymphs, larvae) was monitored weekly, along with temperature and humidity. Reproductive success was evaluated via oviposition and larval hatching.</div><div><em>R. sanguineus</em> s.s. adults survived up to 44 weeks, nymphs up to 20 weeks, and larvae up to 5 weeks. <em>R. innaei</em> showed shorter survival (37, 10, and 4 weeks, respectively)<em>.</em> Successful oviposition and larval hatching occurred outdoors between May´23 and September´23 for both species. However, winter survival was not observed; all ticks died following sub-zero temperatures in December´23.</div><div>Despite the inability to overwinter outdoors, both species can survive for extended periods in spring and summer and may enter homes via dogs, where conditions favor year-round survival. Their ability to transition indoors via dogs, where conditions favor year-round survival, suggests a potential for establishment in Germany through combined indoor and seasonal outdoor persistence.</div></div>","PeriodicalId":49320,"journal":{"name":"Ticks and Tick-borne Diseases","volume":"16 6","pages":"Article 102560"},"PeriodicalIF":3.4,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145363960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Borrelia miyamotoi and Neoehrlichia mikurensis in a cohort of tick-exposed individuals and population controls in Denmark 2002–2021 2002-2021年丹麦接触蜱虫人群中宫本氏疏螺旋体和米库新立克体的流行情况和人口控制

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-10-14 DOI: 10.1016/j.ttbdis.2025.102557

Helene Mens , Rosa Gynthersen , Nanna Skaarup Andersen , Mathilde Ørbæk , Fredrikke C. Knudtzen , Sanne Løkkegaard Larsen , Sigurdur Skarphedinsson , Olga A. Stukolova , Dieuwertje Hoornstra , Joppe W. Hovius , Anne-Mette Lebech

Borrelia miyamotoi and Neoehrlichia mikurensis are recently discovered tick-borne pathogens. The aim of this study was to ascertain the extent of transmission among high-risk groups and healthy controls.

The study design is retrospective cohort study. Blood from a total of 1180 individuals, collected between 2002–2021: (i) 180 tick-exposed individuals, (ii) 400 immunocompromised individuals and (iii) 600 blood donors was included. Infection was examined by a protein array (B. miyamotoi) and PCR.

Neoehrlichia mikurensis DNA was detected in only one individual with Lyme neuroborreliosis (LNB) with symptoms compatible with both infections. Borrelia miyamotoi seroprevalence (being either IgM or IgG positive) among tick-exposed individuals (8.3 %, 95%CI 5.1–13.3) was significantly higher compared to healthy blood donors (1.5 %, 95 % CI 0.8–2.8) and immunocompromised individuals (3.3 %, 95 %CI 1.9–5.5), p < 0.0001. Altogether, 37 of 1180 individuals (3.1 %, 95 %CI 2.2–4.3) were found to be B. miyamotoi seropositive.

Neoehrlichiosis and Borrelia miyamotoi disease should be considered in patients with febrile illness and relevant exposure and in non-characteristic presentations of Lyme borreliosis in Denmark.

宫本疏螺旋体和mikurenneehrichia是最近发现的蜱传病原体。本研究的目的是确定高危人群和健康对照组之间的传播程度。研究设计为回顾性队列研究。从2002-2021年期间收集的总共1180人的血液包括：(i) 180名蜱虫暴露者，（ii） 400名免疫功能低下者和（iii） 600名献血者。用宫氏杆菌（B. miyamotoi）和PCR检测感染情况。仅在一例莱姆病神经疏螺旋体（LNB）患者中检测到mikurensis DNA，其症状与两种感染相一致。与健康献血者（1.5%,95%CI 0.8-2.8）和免疫功能不全者（3.3%,95%CI 1.9-5.5）相比，接触蜱虫的个体（8.3%，IgM或IgG阳性）的宫氏疏螺旋体血清阳性率（p < 0.0001）显著高于健康献血者（8.3%,95%CI 5.1-13.3）。1180例患者中37例（3.1%,95% CI 2.2 ~ 4.3）血清阳性。在丹麦，在有发热性疾病和相关暴露的患者以及莱姆病的非特征性表现的患者中，应考虑新立毛体病和宫本氏疏螺旋体病。

{"title":"Prevalence of Borrelia miyamotoi and Neoehrlichia mikurensis in a cohort of tick-exposed individuals and population controls in Denmark 2002–2021","authors":"Helene Mens , Rosa Gynthersen , Nanna Skaarup Andersen , Mathilde Ørbæk , Fredrikke C. Knudtzen , Sanne Løkkegaard Larsen , Sigurdur Skarphedinsson , Olga A. Stukolova , Dieuwertje Hoornstra , Joppe W. Hovius , Anne-Mette Lebech","doi":"10.1016/j.ttbdis.2025.102557","DOIUrl":"10.1016/j.ttbdis.2025.102557","url":null,"abstract":"<div><div><em>Borrelia miyamotoi</em> and <em>Neoehrlichia mikurensis</em> are recently discovered tick-borne pathogens. The aim of this study was to ascertain the extent of transmission among high-risk groups and healthy controls.</div><div>The study design is retrospective cohort study. Blood from a total of 1180 individuals, collected between 2002–2021: (i) 180 tick-exposed individuals, (ii) 400 immunocompromised individuals and (iii) 600 blood donors was included. Infection was examined by a protein array (<em>B. miyamotoi</em>) and PCR.</div><div><em>Neoehrlichia mikurensis</em> DNA was detected in only one individual with Lyme neuroborreliosis (LNB) with symptoms compatible with both infections. <em>Borrelia miyamotoi</em> seroprevalence (being either IgM or IgG positive) among tick-exposed individuals (8.3 %, 95%CI 5.1–13.3) was significantly higher compared to healthy blood donors (1.5 %, 95 % CI 0.8–2.8) and immunocompromised individuals (3.3 %, 95 %CI 1.9–5.5), <em>p</em> < 0.0001. Altogether, 37 of 1180 individuals (3.1 %, 95 %CI 2.2–4.3) were found to be <em>B. miyamotoi</em> seropositive.</div><div>Neoehrlichiosis and <em>Borrelia miyamotoi</em> disease should be considered in patients with febrile illness and relevant exposure and in non-characteristic presentations of Lyme borreliosis in Denmark.</div></div>","PeriodicalId":49320,"journal":{"name":"Ticks and Tick-borne Diseases","volume":"16 6","pages":"Article 102557"},"PeriodicalIF":3.4,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tickborne microorganisms in Dermacentor andersoni (Acari: Ixodidae) in the Bitterroot Mountains of Western Montana 蒙大拿州西部苦根山安德氏革螨蜱传微生物（蜱螨目：伊蚊科）。

IF 3.4 2区医学 Q2 INFECTIOUS DISEASES

Ticks and Tick-borne Diseases

Pub Date : 2025-10-14 DOI: 10.1016/j.ttbdis.2025.102555

K.L. Clark , J. Villegas Nunez , C. Gentry , A. Gibson , H. Husein , R. Burstein , K. Hamm

The Rocky Mountain wood tick, Dermacentor andersoni Stiles, is the most common human biting tick in the Rocky Mountain region of the USA. Although Rickettsia spp. and Colorado tick fever virus have been studied in D. andersoni in certain areas of their distribution, investigations of most other tickborne pathogens are lacking. Despite the history of Rocky Mountain spotted fever in the Bitterroot Mountains of western Montana, no comprehensive surveys of large numbers of ticks for Rickettsia spp. have been conducted there for >40 years. For the present study, host-seeking adult D. andersoni were collected at multiple sites in canyons on the west side of the Bitterroot Valley in western Montana in spring 2021. Following DNA extraction, ticks were screened by polymerase chain reaction assays for several tick-borne microorganisms. DNA sequence data analysis was conducted to confirm identity and conduct phylogenetic comparisons with reference strain sequences of different organisms. No ticks were found to contain Anaplasma spp., Borrelia spp., or Ehrlichia spp. DNA, and a Babesia sp. was detected in only one tick. However, Bartonella spp. DNA was detected in 2 % of tested ticks. Additionally, five species of Rickettsia, including R. peacockii, R. bellii, R. rhipicephali, R. montanensis, and R. rickettsii, were identified in ticks from different sites. The most prevalent Rickettsia species was R. peacockii and the least common was R. rickettsii (found in only two ticks). The relevance of these findings is discussed in relation to historical and contemporary data on Bartonella spp. and Rickettsia spp.

落基山木蜱（Dermacentor andersoni Stiles）是美国落基山地区最常见的咬人蜱。虽然立克次体和科罗拉多蜱热病毒已经在安德氏蜱分布的某些地区进行了研究，但对大多数其他蜱传病原体的调查缺乏。尽管在蒙大拿州西部的比特根山脉有落基山斑疹热的历史，但在那里没有进行过近40年的立克次体蜱虫的大量全面调查。在本研究中，研究人员于2021年春季在蒙大拿州西部比特鲁特山谷西侧峡谷的多个地点收集了寻找寄主的成年安德森线虫。DNA提取后，采用聚合酶链反应法筛选蜱传微生物。通过DNA序列数据分析，确认不同生物的同源性，并与参考菌株序列进行系统发育比较。未发现蜱含有无原体、伯氏疏螺旋体或埃利希氏体DNA，仅在一只蜱中检测到巴贝斯虫。然而，在2%的蜱中检测到巴尔通体的DNA。此外，在不同地点的蜱中还检出了5种立克次体，包括peacockir、bellii r、rhipicephali r、montanensis r和立克次体。最常见的立克次体种是孔雀立克次体，最不常见的是立克次体（仅在2种蜱中发现）。这些发现的相关性与巴尔通体和立克次体的历史和当代数据进行了讨论。

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