The main objective of this case report is to discuss the differentiation between hyperemesis gravidarum and a brain tumor in the presence of hyperemesis symptoms in the first trimester of pregnancy.
Case report
A patient was initially diagnosed with hyperemesis gravidarum in early pregnancy and was hospitalized. After hospitalization, cerebral hemorrhage and cerebral hernia due to convulsions occurred. Magnetic resonance imaging showed a brain tumor. She underwent a craniotomy and then an artificial abortion. Despite treatment with radiation and chemotherapy, she died 9 months later.
Conclusion
Differentiating between hyperemesis gravidarum and a brain tumor based on a physical examination alone is difficult. Imaging should be performed when exacerbation of consciousness with suspected intracranial organic disease occurs.
{"title":"Malignant brain tumor in early pregnancy mistaken for hyperemesis gravidarum","authors":"Naoki Abe, Maki Goto, Sachino Kira, Mariko Matsuno, Sotaro Hayashi, Miho Oda, Lifa Lee, Yoko To, Satoshi Nishiyama, Hiroshi Tsujioka","doi":"10.1016/j.tjog.2024.07.021","DOIUrl":"10.1016/j.tjog.2024.07.021","url":null,"abstract":"<div><h3>Objectives</h3><div>The main objective of this case report is to discuss the differentiation between hyperemesis gravidarum and a brain tumor in the presence of hyperemesis symptoms in the first trimester of pregnancy.</div></div><div><h3>Case report</h3><div>A patient was initially diagnosed with hyperemesis gravidarum in early pregnancy and was hospitalized. After hospitalization, cerebral hemorrhage and cerebral hernia due to convulsions occurred. Magnetic resonance imaging showed a brain tumor. She underwent a craniotomy and then an artificial abortion. Despite treatment with radiation and chemotherapy, she died 9 months later.</div></div><div><h3>Conclusion</h3><div>Differentiating between hyperemesis gravidarum and a brain tumor based on a physical examination alone is difficult. Imaging should be performed when exacerbation of consciousness with suspected intracranial organic disease occurs.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 128-130"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.11.003
Peng-Hui Wang, Szu-Ting Yang, Jae-Weon Kim
{"title":"Primary cytoreductive surgery for advanced epithelial ovarian cancer patients is still popular in gynecologic oncologists in Korea and Taiwan, particularly apparent in Taiwan","authors":"Peng-Hui Wang, Szu-Ting Yang, Jae-Weon Kim","doi":"10.1016/j.tjog.2024.11.003","DOIUrl":"10.1016/j.tjog.2024.11.003","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 1-3"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This case report aims to present a rare occurrence of fallopian tube prolapse into the vaginal vault following hysterectomy, underscoring the importance of recognizing this uncommon complication.
Case Report
A 45-year-old woman, with a history of hysterectomy for adenomyosis, presented with symptoms mimicking a vaginal tumor, including persistent discharge, abdominal pain, postcoital bleeding, and weight loss. Imaging raised concerns of malignancy, but surgery revealed a prolapsed fallopian tube with chronic inflammation. This case highlights the diagnostic challenges, with less than 100 reported instances. Differential diagnoses encompassed diverse pelvic pathologies, necessitating histological confirmation. Factors contributing to prolapse include poor vault closure and early sexual activity. Awareness of this complication is pivotal when evaluating post-hysterectomy symptoms, ensuring precise diagnosis and appropriate management.
Conclusion
Fallopian tube prolapse into the vaginal vault is a rare post-hysterectomy complication. Early recognition and accurate diagnosis are essential for effective management of patients presenting with post-hysterectomy symptoms, such as vaginal bleeding and discharge.
{"title":"Prolapsed fallopian tube to the vagina after hysterectomy a year ago: A case report","authors":"Yu-Hsuan Lin , Huang-Ping Shen , Chih-Jen Tseng , Liang-Ying Wu , Li-Hsin Hsia","doi":"10.1016/j.tjog.2024.04.021","DOIUrl":"10.1016/j.tjog.2024.04.021","url":null,"abstract":"<div><h3>Objective</h3><div>This case report aims to present a rare occurrence of fallopian tube prolapse into the vaginal vault following hysterectomy, underscoring the importance of recognizing this uncommon complication.</div></div><div><h3>Case Report</h3><div>A 45-year-old woman, with a history of hysterectomy for adenomyosis, presented with symptoms mimicking a vaginal tumor, including persistent discharge, abdominal pain, postcoital bleeding, and weight loss. Imaging raised concerns of malignancy, but surgery revealed a prolapsed fallopian tube with chronic inflammation. This case highlights the diagnostic challenges, with less than 100 reported instances. Differential diagnoses encompassed diverse pelvic pathologies, necessitating histological confirmation. Factors contributing to prolapse include poor vault closure and early sexual activity. Awareness of this complication is pivotal when evaluating post-hysterectomy symptoms, ensuring precise diagnosis and appropriate management.</div></div><div><h3>Conclusion</h3><div>Fallopian tube prolapse into the vaginal vault is a rare post-hysterectomy complication. Early recognition and accurate diagnosis are essential for effective management of patients presenting with post-hysterectomy symptoms, such as vaginal bleeding and discharge.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 155-158"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.09.023
Ivana Joksic , Mina Toljic , Nela Maksimovic , Dijana Perovic , Tatjana Damnjanovic , Aleksandar Jurisic
Objective
Prenatal detection of complex chromosomal rearrangements (CCR) is extremely rare, but is of great clinical importance, since CCR can be causative of different congenital disorders. We present an exceptionally rare case of prenatally diagnosed Saethre-Chotzen syndrome (SCS) rising as a consequence of chromothripsis involving chromosomes 5, 7 and 11 and deletion of TWIST1 gene.
Case report
Brachycephaly, hypertelorism, flat face, micrognathia, relative macroglossia and small posterior fossa were noted on ultrasound examination at 28th gestational week. Fetal karyotyping revealed de novo translocation 46,XY,t(7;11)(p15.5;q21)dn. Chromosomal microarray showed presence of three microdeletions on chromosome 7 (7p21.1p15.3 including TWIST1, 7p12.1p11.2 and 7q21.11), and one on chromosome 5p12p11.
Conclusion
Use of advanced molecular diagnostic techniques in combination with cytogenetic methods allows for precise characterization of CCRs and detection of molecular mechanisms of their origin. Phenomenon of chromothripsis can be causative of rare genetic syndromes such as SCS.
{"title":"Prenatal diagnosis of chromothripsis causing complex chromosomal rearrangement involving chromosomes 5, 7 and 11 leading to TWIST1 deletion and Saethre-Chotzen syndrome","authors":"Ivana Joksic , Mina Toljic , Nela Maksimovic , Dijana Perovic , Tatjana Damnjanovic , Aleksandar Jurisic","doi":"10.1016/j.tjog.2024.09.023","DOIUrl":"10.1016/j.tjog.2024.09.023","url":null,"abstract":"<div><h3>Objective</h3><div>Prenatal detection of complex chromosomal rearrangements (CCR) is extremely rare, but is of great clinical importance, since CCR can be causative of different congenital disorders. We present an exceptionally rare case of prenatally diagnosed Saethre-Chotzen syndrome (SCS) rising as a consequence of chromothripsis involving chromosomes 5, 7 and 11 and deletion of <em>TWIST1</em> gene.</div></div><div><h3>Case report</h3><div>Brachycephaly, hypertelorism, flat face, micrognathia, relative macroglossia and small posterior fossa were noted on ultrasound examination at 28th gestational week. Fetal karyotyping revealed <em>de novo</em> translocation 46,XY,t(7;11)(p15.5;q21)dn. Chromosomal microarray showed presence of three microdeletions on chromosome 7 (7p21.1p15.3 including <em>TWIST1</em>, 7p12.1p11.2 and 7q21.11), and one on chromosome 5p12p11.</div></div><div><h3>Conclusion</h3><div>Use of advanced molecular diagnostic techniques in combination with cytogenetic methods allows for precise characterization of CCRs and detection of molecular mechanisms of their origin. Phenomenon of chromothripsis can be causative of rare genetic syndromes such as SCS.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 134-137"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.10.007
Chih-Ping Chen
{"title":"High-level mosaicism for 45,X in 45,X/46,XX at amniocentesis in a pregnancy with positive non-invasive prenatal testing for Turner syndrome, postnatal decrease of the 45,X cell line and a favorable fetal outcome","authors":"Chih-Ping Chen","doi":"10.1016/j.tjog.2024.10.007","DOIUrl":"10.1016/j.tjog.2024.10.007","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 178-179"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.10.012
Dubravko Habek, Neven Tučkar
{"title":"Inflamed hemostatic sponge (oxidized cellulose) with actinomycosis as a cause of postoperative pelvic abscess","authors":"Dubravko Habek, Neven Tučkar","doi":"10.1016/j.tjog.2024.10.012","DOIUrl":"10.1016/j.tjog.2024.10.012","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 199-200"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.09.022
Lin-Yu Chen , Hsing-Yu Chen , Hung-Cheng Lai , Shiou-Fu Lin , Kuo-Chang Wen , Darmawi , Phui-Ly Liew
Objective
Endometrial cancer (EC) shows substantial heterogeneity in their immune microenvironment. BHLHE22 is consistently hypermethylated in EC and high expression of BHLHE22 is likely to be immunosuppressive in the tumor microenvironment. Herein, we evaluated expression of BHLHE22, programmed cell death ligand-1 (PD-L1), CD8, CD68 and mismatch repair proteins in EC.
Materials and methods
Immunohistochemistry on tissue microarray sections in primary EC to quantify BHLHE22, PD-L1, CD8 and CD68 was performed. The associations between the clinicopathological characteristics, mismatch repair status, and Kaplan–Meier analyses (including The Cancer Genome Atlas (TCGA) dataset) were analyzed.
Results
Twenty-nine of 109 cases (26.6 %) had high BHLHE22 expression, which was associated with higher tumoral CD8, higher stromal CD68 and lower progesterone receptor (PR). Survival analysis of the TCGA dataset showed better overall survival in subgroups with high BHLHE22/high CD8, high BHLHE22/low M2 macrophage, and high BHLHE22/low myeloid-derived suppressor cell. The transcription start site region of BHLHE22 contained many predicted PR-binding elements. In EC cells, BHLHE22 expression increased with time after exposure to progesterone. Of the 115 ECs, 29 (25.2 %) had microsatellite instability. Mismatch repair-deficient ECs exhibited significantly more CD8-positive tumoral/stromal T lymphocytes and macrophages, and a higher percentage of PD-L1-positive immune cells occupying the tumor. Low expression of stromal CD8 and tumoral CD68 was associated with better overall survival. Overall survival did not differ significantly between patients with low or high PD-L1 expression.
Conclusion
Increased numbers of CD8-positive cytotoxic T lymphocytes, CD68-positive macrophages, and PD-L1-positive tumor/immune cells were observed in MMR-deficient EC. BHLHE22 expression was associated with the PR regulatory and immune-related pathways.
{"title":"The expression of BHLHE22 in endometrial carcinoma: Associations with mismatch repair protein expression status, tumor-infiltrating immune cells, programmed death-ligand 1 and clinical outcomes","authors":"Lin-Yu Chen , Hsing-Yu Chen , Hung-Cheng Lai , Shiou-Fu Lin , Kuo-Chang Wen , Darmawi , Phui-Ly Liew","doi":"10.1016/j.tjog.2024.09.022","DOIUrl":"10.1016/j.tjog.2024.09.022","url":null,"abstract":"<div><h3>Objective</h3><div>Endometrial cancer (EC) shows substantial heterogeneity in their immune microenvironment. <em>BHLHE22</em> is consistently hypermethylated in EC and high expression of BHLHE22 is likely to be immunosuppressive in the tumor microenvironment. Herein, we evaluated expression of BHLHE22, programmed cell death ligand-1 (PD-L1), CD8, CD68 and mismatch repair proteins in EC.</div></div><div><h3>Materials and methods</h3><div>Immunohistochemistry on tissue microarray sections in primary EC to quantify BHLHE22, PD-L1, CD8 and CD68 was performed. The associations between the clinicopathological characteristics, mismatch repair status, and Kaplan–Meier analyses (including The Cancer Genome Atlas (TCGA) dataset) were analyzed.</div></div><div><h3>Results</h3><div>Twenty-nine of 109 cases (26.6 %) had high BHLHE22 expression, which was associated with higher tumoral CD8, higher stromal CD68 and lower progesterone receptor (PR). Survival analysis of the TCGA dataset showed better overall survival in subgroups with high BHLHE22/high CD8, high BHLHE22/low M2 macrophage, and high BHLHE22/low myeloid-derived suppressor cell. The transcription start site region of <em>BHLHE22</em> contained many predicted PR-binding elements. In EC cells, BHLHE22 expression increased with time after exposure to progesterone. Of the 115 ECs, 29 (25.2 %) had microsatellite instability. Mismatch repair-deficient ECs exhibited significantly more CD8-positive tumoral/stromal T lymphocytes and macrophages, and a higher percentage of PD-L1-positive immune cells occupying the tumor. Low expression of stromal CD8 and tumoral CD68 was associated with better overall survival. Overall survival did not differ significantly between patients with low or high PD-L1 expression.</div></div><div><h3>Conclusion</h3><div>Increased numbers of CD8-positive cytotoxic T lymphocytes, CD68-positive macrophages, and PD-L1-positive tumor/immune cells were observed in MMR-deficient EC. BHLHE22 expression was associated with the PR regulatory and immune-related pathways.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 110-119"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143055756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.10.003
Ching-Hsiang Yu , En-Chih Liao , Yu-Jang Su
Objective
Bongkrekic acid (BKA) is a life-threatening toxin linked to foodborne illnesses. Herein, we report two fatalities among 33 patients who ingested BKA in March 2024, East Taipei, Taiwan.
Case Report
Our first case involved a 40-year-old female who presented with nausea, vomiting, and diarrhea after consuming wet rice noodles. On examination, refractory hypotension, jaundice, diffuse abdominal pain, high levels of liver enzymes, metabolic acidosis, coagulopathy, and acute hepatic failure were present. Dialysis, continuous venovenous hemofiltration, and plasma exchange were performed; however, the patient experienced liver failure and died of multi-organ failure, severe sepsis, and coagulopathy on day 39. The second case, a 39-year-old man, was found unconscious and experiencing cardiac arrest. He eventually died after 30 min of cardiopulmonary resuscitation following admission to the intensive care unit.
Conclusion
Strengthening food safety regulations by enhancing inspection of food production, storage, and preparation facilities should be implemented to prevent BKA poisoning-related fatalities.
{"title":"Unexpectedly life-threatening meal: Contamination by Bongkrekic acid in Taiwan","authors":"Ching-Hsiang Yu , En-Chih Liao , Yu-Jang Su","doi":"10.1016/j.tjog.2024.10.003","DOIUrl":"10.1016/j.tjog.2024.10.003","url":null,"abstract":"<div><h3>Objective</h3><div>Bongkrekic acid (BKA) is a life-threatening toxin linked to foodborne illnesses. Herein, we report two fatalities among 33 patients who ingested BKA in March 2024, East Taipei, Taiwan.</div></div><div><h3>Case Report</h3><div>Our first case involved a 40-year-old female who presented with nausea, vomiting, and diarrhea after consuming wet rice noodles. On examination, refractory hypotension, jaundice, diffuse abdominal pain, high levels of liver enzymes, metabolic acidosis, coagulopathy, and acute hepatic failure were present. Dialysis, continuous venovenous hemofiltration, and plasma exchange were performed; however, the patient experienced liver failure and died of multi-organ failure, severe sepsis, and coagulopathy on day 39. The second case, a 39-year-old man, was found unconscious and experiencing cardiac arrest. He eventually died after 30 min of cardiopulmonary resuscitation following admission to the intensive care unit.</div></div><div><h3>Conclusion</h3><div>Strengthening food safety regulations by enhancing inspection of food production, storage, and preparation facilities should be implemented to prevent BKA poisoning-related fatalities.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 142-145"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.09.021
Ying Feng , Huiqiao Gao , Fang Liu , Shuzhen Wang , Meizhu Xiao
Objective
To study immediate therapeutic outcomes, subsequent fertility effects and menstrual changes in cesarean scar pregnancy patients who received uterine artery embolization with or without methotrexate followed by ultrasound guided curettage.
Materials and methods
Totally, 82 patients who met the inclusion criteria were enrolled in our study and divided into two groups. Group I included 50 patients who received uterine artery embolization and ultrasound guided curettage, and Group II had 32 patients who received uterine artery embolization plus methotrexate and ultrasound guided curettage.
Results
No significant difference was found in demographic features between the two groups, but the level of serum β-human chorionic gonadotropin before uterine artery embolization, 1 day and 7 days after ultrasound guided curettage is significantly higher in Group II than that in Group I. Patients were followed up for a mean time of 38.9 months. 10 patients had reproductive desire and half of them failed while half succeeded including one recurrent cesarean scar pregnancy. Most patients (74.4 %) had no menstrual changes, while 19 patients complaint a decrease in menstruation and 2 patients had a prolonged menstruation.
Conclusion
Uterine artery embolization combined with or without methotrexate plus ultrasound guided curettage is an effective, safe and recommended therapy to eliminate the gestational sac and meanwhile to preserve fertility for cesarean scar pregnancy patients, and methotrexate could help reduce the blood level of β-human chorionic gonadotropin and shorten the days to recover to normal, thus reducing hospitalized days.
{"title":"Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital","authors":"Ying Feng , Huiqiao Gao , Fang Liu , Shuzhen Wang , Meizhu Xiao","doi":"10.1016/j.tjog.2024.09.021","DOIUrl":"10.1016/j.tjog.2024.09.021","url":null,"abstract":"<div><h3>Objective</h3><div>To study immediate therapeutic outcomes, subsequent fertility effects and menstrual changes in cesarean scar pregnancy patients who received uterine artery embolization with or without methotrexate followed by ultrasound guided curettage.</div></div><div><h3>Materials and methods</h3><div>Totally, 82 patients who met the inclusion criteria were enrolled in our study and divided into two groups. Group I included 50 patients who received uterine artery embolization and ultrasound guided curettage, and Group II had 32 patients who received uterine artery embolization plus methotrexate and ultrasound guided curettage.</div></div><div><h3>Results</h3><div>No significant difference was found in demographic features between the two groups, but the level of serum β-human chorionic gonadotropin before uterine artery embolization, 1 day and 7 days after ultrasound guided curettage is significantly higher in Group II than that in Group I. Patients were followed up for a mean time of 38.9 months. 10 patients had reproductive desire and half of them failed while half succeeded including one recurrent cesarean scar pregnancy. Most patients (74.4 %) had no menstrual changes, while 19 patients complaint a decrease in menstruation and 2 patients had a prolonged menstruation.</div></div><div><h3>Conclusion</h3><div>Uterine artery embolization combined with or without methotrexate plus ultrasound guided curettage is an effective, safe and recommended therapy to eliminate the gestational sac and meanwhile to preserve fertility for cesarean scar pregnancy patients, and methotrexate could help reduce the blood level of β-human chorionic gonadotropin and shorten the days to recover to normal, thus reducing hospitalized days.</div></div>","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 86-91"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.tjog.2024.11.005
Yiu-Tai Li, Szu-Ting Yang, Peng-Hui Wang
{"title":"Expression of female hormone receptor and prognosis of cervical cancer: Does any relationship exist?","authors":"Yiu-Tai Li, Szu-Ting Yang, Peng-Hui Wang","doi":"10.1016/j.tjog.2024.11.005","DOIUrl":"10.1016/j.tjog.2024.11.005","url":null,"abstract":"","PeriodicalId":49449,"journal":{"name":"Taiwanese Journal of Obstetrics & Gynecology","volume":"64 1","pages":"Pages 6-7"},"PeriodicalIF":2.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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