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Atherogenicity, Oxidative Stress, Heavy Metals and Bioelements Status in Hypertensive Nigerians in an Urban Population 尼日利亚城市高血压人群的动脉粥样硬化性、氧化应激、重金属和生物元素状况
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-28 DOI: 10.9734/ajmah/2023/v21i11934
Oyedeji Samuel Oyewole, Adesina Adeyemi Adeleke, Oke Olusegun Taiwo, Adeosun Oyebola Ganiyu, Awe Kunle
Objectives: This study investigated levels of measured parameters; bio-elements (zinc, copper, selenium, chromium, and manganese), heavy metals (cadmium and lead), oxidative stress biomarkers (vitamin C, Vitamin E, reduced Glutathione-GSH and malondialdehyde-MDA) and lipid profile (cholesterol-CHOL, triglyceride- TG, high-density lipoprotein- HDL, low-density lipoprotein- LDL and VLDL) in primary hypertensive individuals. Materials and Methods: A total of 74 confirmed hypertensive individuals (30 males, 44 females) of 30-55 years (test subjects) and 46 (22males, 24 females) age-matched apparently healthy normotensive individuals (control) were involved in this study. Atomic absorption spectrophotometer was used to determine the concentrations of bio-elements and toxic metals while spectrophotometric methods were used for the concentrations of oxidative stress biomarkers and lipid fractions. Results: Comparative analysis between test and control subjects showed significantly reduced concentrations of vitamins C and E, GSH, the bio-elements, HDL and Zinc/Copper ratio. Significantly elevated concentrations of the toxic metals, MDA, CHOL, TG, LDL, and VLDL, the atherogenic indices- LDL/HDL, TC/HDL, and TG/HDL as well as Cadmium/ Zinc ratio. There was indirect association between the bio-elements and atherogenic lipid fractions but a direct correlation with HDL. Also, negative correlations were observed between the heavy metals and the antioxidants biomolecules. Conclusion: The concentrations of the measured bio-elements, vitamins C and E, GSH and HDL were significantly lower in hypertensive individuals while the levels of heavy metals, cholesterol, TG, LDL and MDA were significantly higher.
目的:本研究调查了测量参数的水平;原发性高血压患者的生物元素(锌、铜、硒、铬和锰)、重金属(镉和铅)、氧化应激生物标志物(维生素C、维生素E、还原性谷胱甘肽-谷胱甘肽-谷胱甘肽和丙二醛- mda)和脂质谱(胆固醇- chol、甘油三酯- TG、高密度脂蛋白- HDL、低密度脂蛋白- LDL和VLDL)。 材料与方法:研究对象为30 ~ 55岁确诊高血压患者74例(男30例,女44例),对照组为46例(男22例,女24例)。原子吸收分光光度法测定生物元素和有毒金属的浓度,分光光度法测定氧化应激生物标志物和脂质组分的浓度。 结果:实验组与对照组的比较分析显示,维生素C和E、谷胱甘肽、生物元素、高密度脂蛋白和锌/铜比显著降低。毒性金属、MDA、CHOL、TG、LDL、VLDL浓度显著升高,动脉粥样硬化指数LDL/HDL、TC/HDL、TG/HDL及镉/锌比值显著升高。生物元素与动脉粥样硬化脂质组分之间存在间接关联,但与HDL之间存在直接关联。此外,重金属与抗氧化剂生物分子呈负相关。 结论:高血压患者体内生物元素、维生素C、维生素E、GSH、HDL浓度显著降低,而重金属、胆固醇、TG、LDL、MDA水平显著升高。
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 Materials and Methods: A total of 74 confirmed hypertensive individuals (30 males, 44 females) of 30-55 years (test subjects) and 46 (22males, 24 females) age-matched apparently healthy normotensive individuals (control) were involved in this study. Atomic absorption spectrophotometer was used to determine the concentrations of bio-elements and toxic metals while spectrophotometric methods were used for the concentrations of oxidative stress biomarkers and lipid fractions.
 Results: Comparative analysis between test and control subjects showed significantly reduced concentrations of vitamins C and E, GSH, the bio-elements, HDL and Zinc/Copper ratio. Significantly elevated concentrations of the toxic metals, MDA, CHOL, TG, LDL, and VLDL, the atherogenic indices- LDL/HDL, TC/HDL, and TG/HDL as well as Cadmium/ Zinc ratio. There was indirect association between the bio-elements and atherogenic lipid fractions but a direct correlation with HDL. Also, negative correlations were observed between the heavy metals and the antioxidants biomolecules.
 Conclusion: The concentrations of the measured bio-elements, vitamins C and E, GSH and HDL were significantly lower in hypertensive individuals while the levels of heavy metals, cholesterol, TG, LDL and MDA were significantly higher.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"51 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136158775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review of Airbag Injuries: A Sri Lankan Case Series 安全气囊损伤综述:斯里兰卡病例系列
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-26 DOI: 10.9734/ajmah/2023/v21i11933
None Hulathduwa S. R., None Priyanath W. A. K. M.
The deployment of airbags in vehicles has significantly contributed to occupant safety during accidents. This review article discusses their history, evolution, types, chemical composition, mechanisms, defects, safety issues and hazardous practices by vehicle occupants. The evolution of airbags, from early designs to advanced designs is presented highlighting their life-saving impact and defects. The article addresses common hazardous practices by vehicle occupants that could lead to airbag-related injuries such as resting hands or feet on the dashboard. A series of typical and atypical airbag-related injuries from Sri Lanka is given in the latter part of the article. These cases include incidents of metal objects detaching from airbags causing fatal injuries, fractures resulting from improper hand placement during airbag deployment, burns, cranio-facial and dental injuries and so on.
安全气囊在车辆中的部署对事故中乘员的安全做出了重大贡献。本文就其历史、演变、类型、化学成分、作用机理、缺陷、安全问题及车辆乘员的危害行为进行了综述。安全气囊的演变,从早期的设计到先进的设计,突出了他们的生命影响和缺陷。这篇文章讨论了车辆乘员可能导致安全气囊相关伤害的常见危险行为,例如将手或脚放在仪表板上。一系列典型和非典型的安全气囊相关的伤害从斯里兰卡给出了文章的后一部分。这些案例包括金属物体从安全气囊中脱落造成致命伤害的事件,在安全气囊打开过程中不正确的手放置导致的骨折,烧伤,颅面和牙齿损伤等等。
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引用次数: 0
Assessment of Obstetric Characteristics Associate with Anemia Disease among Pregnant Women Attending Antenatal Clinics at Garowe General Hospital, Somalia 索马里加洛韦总医院产前门诊孕妇与贫血疾病相关的产科特征评估
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-25 DOI: 10.9734/ajmah/2023/v21i11932
Mawlid Abdirisak Muse, Joseph Juma, Teresia Ngonjo
Introduction: Existence of anaemia pregnancy women is when it comes to this hematologic abnormality. Hemoglobin deficiency during pregnancy has serious effect on maternal and fetus development, which could prompt high maternal mortality rates. Purpose of the Study: The purpose of the study was to assess obstetric characteristics associate with anemia disease among pregnant women attending antenatal clinics at Garowe general hospital. Methods: A hospital based cross-sectional study design was conducted. Systematic random sampling method was used to select 266 pregnant women. Mothers who attended Antenatal Clinic during the study period and who met the inclusion criteria were interviewed and a capillary blood sample was taken. Hemoglobin level was determined by using HemoCue photometer. A structured questionnaire as well as focus group discussions were held in collecting data. Qualitative data was analyzed using a content technique and quantitative data was analyzed using descriptive and inferential statistics. Results: The inferential statistics entailed a bivariate chi-square analysis and odds ratio (OR) with corresponding 95% confidence intervals (CI) computed to find association between independent and dependent variables. The study found that 46% of the pregnant women in the study were anemic. Obstetric characteristics such as the interval or space between births and the abortion history of the mother was significantly associated with anemia disease. Recommendation: The study recommends that stakeholders including governments, Non-Governmental Oganization and the private sector in Somalia should seek to increase access to iron and folic acid supplements, should increase education on nutrition. In addition, the study recommends that sanitation and access to clean water should also be enhanced. Finally, the study recommends that the underlying socio-economic factors such as poverty, lack of education, unemployment and poor housing that lead to anemia should be addressed.
孕妇贫血的存在是当它涉及到这种血液学异常。妊娠期血红蛋白缺乏严重影响母体和胎儿的发育,可导致高孕产妇死亡率。 研究目的:本研究的目的是评估在Garowe综合医院产前诊所就诊的孕妇中与贫血疾病相关的产科特征。& # x0D;方法:采用基于医院的横断面研究设计。采用系统随机抽样方法对266名孕妇进行调查。在研究期间到产前诊所就诊并符合纳入标准的母亲接受了访谈,并采集了毛细血管血样。用HemoCue光度计测定血红蛋白水平。在收集数据方面,进行了结构化问卷调查和焦点小组讨论。定性数据采用内容分析方法,定量数据采用描述统计和推理统计方法。 结果:推断统计包括双变量卡方分析和比值比(OR),并计算相应的95%置信区间(CI),以发现自变量和因变量之间的关联。研究发现,46%的孕妇患有贫血症。产科特征,如分娩间隔或间隔以及母亲的流产史与贫血疾病显著相关。 建议:该研究建议,包括索马里政府、非政府组织和私营部门在内的利益攸关方应寻求增加获得铁和叶酸补充剂的机会,并应加强营养教育。此外,该研究还建议,卫生设施和获得清洁水的机会也应得到加强。最后,该研究建议,应解决导致贫血的潜在社会经济因素,如贫困、缺乏教育、失业和住房条件差。
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 Purpose of the Study: The purpose of the study was to assess obstetric characteristics associate with anemia disease among pregnant women attending antenatal clinics at Garowe general hospital. 
 Methods: A hospital based cross-sectional study design was conducted. Systematic random sampling method was used to select 266 pregnant women. Mothers who attended Antenatal Clinic during the study period and who met the inclusion criteria were interviewed and a capillary blood sample was taken. Hemoglobin level was determined by using HemoCue photometer. A structured questionnaire as well as focus group discussions were held in collecting data. Qualitative data was analyzed using a content technique and quantitative data was analyzed using descriptive and inferential statistics.
 Results: The inferential statistics entailed a bivariate chi-square analysis and odds ratio (OR) with corresponding 95% confidence intervals (CI) computed to find association between independent and dependent variables. The study found that 46% of the pregnant women in the study were anemic. Obstetric characteristics such as the interval or space between births and the abortion history of the mother was significantly associated with anemia disease.
 Recommendation: The study recommends that stakeholders including governments, Non-Governmental Oganization and the private sector in Somalia should seek to increase access to iron and folic acid supplements, should increase education on nutrition. In addition, the study recommends that sanitation and access to clean water should also be enhanced. Finally, the study recommends that the underlying socio-economic factors such as poverty, lack of education, unemployment and poor housing that lead to anemia should be addressed.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135113548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endometriosis of the Appendix: A Narrative Review 阑尾子宫内膜异位症:述评
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-16 DOI: 10.9734/ajmah/2023/v21i11931
None Kumar H. R., None Soma M., None Saw M. O.
Endometriosis of the appendix is condition that is seen in young women, and it clinically presents with chronic lower abdominal pain. It is one of the sites of extra pelvic endometriosis and it is confirmed on histopathological evaluation of the appendix. The dilemma for the surgeon is if an appendectomy is to be performed or not. The introduction of laparoscopic surgery has made visualization of the pelvis and appendix easier, and we have conducted this narrative review article to see if an appendectomy should be performed in all cases of endometriosis.
阑尾子宫内膜异位症常见于年轻女性,临床表现为慢性下腹痛。它是盆腔外子宫内膜异位症的一个部位,在阑尾的组织病理学评估中得到证实。外科医生进退两难的是是否要做阑尾切除术。腹腔镜手术的引入使骨盆和阑尾的可视化更容易,我们进行了这篇叙述性回顾文章,看看是否应该在所有子宫内膜异位症的病例中进行阑尾切除术。
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引用次数: 0
Quadruple Arterial Blood Supply to the Liver: A Rare Variation 肝脏四动脉供血:罕见变异
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-12 DOI: 10.9734/ajmah/2023/v21i11930
None Bello S. S., Aliu Abdulhameed
Introduction: Vascular variations in the liver are significant to surgeons in liver transplantations, radiological procedures, laparoscopy and penetrating abdominal injuries. These variations are important in liver transplantation procedure, in addition to being an ideal opportunity for surgical anatomy study, their detailed identification is crucial to the success of the procedure. Case Report: During a routine cadaveric dissection of the abdomen for medical students at the department of Anatomy Usmanu Danfodiyo University, Sokoto Nigeria. A male adult cadaver with unknown identity and cause of death, was found to have four arterial branches to the liver, one each from the left gastric artery and common hepatic artery, a branch from the gastro-duodenal artery and the hepatic artery. Conclusion: Detailed knowledge of the variations of hepatic arterial anatomy is of utmost importance to surgeons who perform surgeries in this area, particularly in liver transplantation, since their identification and proper management are critical to the success of the procedure.
简介:肝脏血管变异对肝移植、放射治疗、腹腔镜检查和穿透性腹部损伤的外科医生具有重要意义。这些变异在肝移植手术中很重要,除了是外科解剖研究的理想机会外,它们的详细识别对手术的成功至关重要。 病例报告:在尼日利亚索科托Usmanu Danfodiyo大学解剖系医学生的腹部常规尸体解剖过程中。一具男性成年尸体,身份和死因不明,发现有四条动脉分支通往肝脏,分别来自左胃动脉和肝总动脉,胃十二指肠动脉和肝动脉分支。结论:对肝动脉解剖变化的详细了解对于在该领域进行手术的外科医生来说是至关重要的,特别是在肝移植手术中,因为它们的识别和适当的处理对手术的成功至关重要。
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 Case Report: During a routine cadaveric dissection of the abdomen for medical students at the department of Anatomy Usmanu Danfodiyo University, Sokoto Nigeria. A male adult cadaver with unknown identity and cause of death, was found to have four arterial branches to the liver, one each from the left gastric artery and common hepatic artery, a branch from the gastro-duodenal artery and the hepatic artery.
 Conclusion: Detailed knowledge of the variations of hepatic arterial anatomy is of utmost importance to surgeons who perform surgeries in this area, particularly in liver transplantation, since their identification and proper management are critical to the success of the procedure.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135968300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Influencing Utilisation of Hernia Care among Women Seeking Surgical Healthcare: A Study of a Peri-urban Health Facility in Eastern Ghana 影响寻求外科医疗保健的妇女使用疝气护理的因素:对加纳东部城郊卫生设施的研究
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-06 DOI: 10.9734/ajmah/2023/v21i11928
Augustine Adomah-Afari, Akua Kyekye Addo-Kwafo
Aims: To assess factors associated with the utilization of quality hernia care among female adults seeking healthcare. Study Design: A descriptive cross-sectional design was used. Place and Duration of Study: Nsawam Government Hospital in the Nsawam-Adoagyiri Municipality of the Eastern Region of Ghana between May 15th and June 15th, 2022. Methodology: We applied a quantitative research method where both self-administered and interviewer-administered strategies were applied to administer a structured questionnaire. A consecutive sampling approach was used to recruit a total of 180 women who sought surgical care. Data was analyzed using STATA version 15 Software. Descriptive statistics, chi-square test, and multiple logistic regression analysis were applied to determine the relationship between the dependent and independent variables. The level of significance was accepted at P=.05 at a 95% confidence interval. Results: Overall, 180 women took part in the study out of the estimated sample size of 189, giving a response rate of 95.2%. The proportion of hernia among the women was 56% out of which the common types were umbilical hernia (32%) and incisional hernia (12%). The rate of utilization of hernia care was 75%. Logistic regression showed that marital status (being single) (aOR = 0.03; 95% CI = 0.002-0.20; P =.001), occupation (traders) (aOR = 0.03; 95% CI = 0.003-0.35; P = .004), and reliance on traditional healers (aOR = 0.11; 95% CI = 0.02-0.74; P = .024) were significant predictors of utilization of hernia care. Conclusion: The study showed a high proportion of hernia cases among women seeking surgical care. The majority of these hernias were inguinal hernia followed by umbilical and incisional hernia. The study suggests that managers at the hospital level, policymakers, and stakeholders in the health sector should ensure the provision of affordable hernia care for women such that early detection would be one of the key strategies to prevent imminent complications or limitations to daily activity.
目的:评估寻求医疗保健的成年女性疝气护理质量的相关因素。 研究设计:采用描述性横断面设计。 学习地点和时间:2022年5月15日至6月15日,加纳东部地区恩萨瓦姆-阿多agyiri市的恩萨瓦姆政府医院。方法:我们采用定量研究方法,采用自我管理和访谈者管理两种策略来管理结构化问卷。采用连续抽样方法,共招募180名寻求手术治疗的妇女。数据分析采用STATA version 15软件。采用描述性统计、卡方检验和多元逻辑回归分析确定因变量和自变量之间的关系。在P=时接受显著性水平。0.05, 95%置信区间。 结果:总体而言,在估计的189个样本量中,有180名妇女参加了研究,回复率为95.2%。妇女疝的比例为56%,其中常见的类型为脐疝(32%)和切口疝(12%)。疝护理使用率为75%。Logistic回归显示婚姻状况(单身)(aOR = 0.03;95% ci = 0.002-0.20;P =.001)、职业(贸易商)(aOR = 0.03;95% ci = 0.003-0.35;P = 0.004),对传统治疗师的依赖(aOR = 0.11;95% ci = 0.02-0.74;P = 0.024)是疝护理使用率的显著预测因子。& # x0D;结论:该研究显示,在寻求手术治疗的女性中,疝气病例的比例很高。以腹股沟疝居多,其次为脐疝和切口疝。该研究表明,医院一级的管理人员、政策制定者和卫生部门的利益相关者应确保为妇女提供负担得起的疝气护理,以便早期发现将成为防止即将发生的并发症或限制日常活动的关键策略之一。
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 Study Design: A descriptive cross-sectional design was used.
 Place and Duration of Study: Nsawam Government Hospital in the Nsawam-Adoagyiri Municipality of the Eastern Region of Ghana between May 15th and June 15th, 2022.
 Methodology: We applied a quantitative research method where both self-administered and interviewer-administered strategies were applied to administer a structured questionnaire. A consecutive sampling approach was used to recruit a total of 180 women who sought surgical care. Data was analyzed using STATA version 15 Software. Descriptive statistics, chi-square test, and multiple logistic regression analysis were applied to determine the relationship between the dependent and independent variables. The level of significance was accepted at P=.05 at a 95% confidence interval.
 Results: Overall, 180 women took part in the study out of the estimated sample size of 189, giving a response rate of 95.2%. The proportion of hernia among the women was 56% out of which the common types were umbilical hernia (32%) and incisional hernia (12%). The rate of utilization of hernia care was 75%. Logistic regression showed that marital status (being single) (aOR = 0.03; 95% CI = 0.002-0.20; P =.001), occupation (traders) (aOR = 0.03; 95% CI = 0.003-0.35; P = .004), and reliance on traditional healers (aOR = 0.11; 95% CI = 0.02-0.74; P = .024) were significant predictors of utilization of hernia care. 
 Conclusion: The study showed a high proportion of hernia cases among women seeking surgical care. The majority of these hernias were inguinal hernia followed by umbilical and incisional hernia. The study suggests that managers at the hospital level, policymakers, and stakeholders in the health sector should ensure the provision of affordable hernia care for women such that early detection would be one of the key strategies to prevent imminent complications or limitations to daily activity.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135351674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perforated Peptic Ulcer-Current Management: A Narrative Review 穿孔性消化性溃疡-当前治疗:叙述性回顾
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-06 DOI: 10.9734/ajmah/2023/v21i11927
None Kumar H. R., None Soma M., None Saw M. O.
Perforated peptic ulcer is a complication of peptic ulcer disease with its incidence being stable despite the introduction of proton pump inhibitors. This condition is seen in older patients with comorbidities and early diagnosis improves the mortality of this condition. The treatment of perforated peptic ulcer is performed by closure of the perforated peptic ulcer, and this procedure can be performed by open or laparoscopic surgery. The current trend over the last few years has been the use of laparoscopic surgery in the management of perforated peptic ulcer and we have conducted this narrative review article to investigate the current trend in management of this condition.
穿孔性消化性溃疡是消化性溃疡的一种并发症,尽管引入了质子泵抑制剂,但其发病率仍保持稳定。这种情况见于有合并症的老年患者,早期诊断可提高这种情况的死亡率。穿孔性消化性溃疡的治疗是通过闭合穿孔性消化性溃疡来完成的,这个过程可以通过开放或腹腔镜手术来完成。在过去的几年里,目前的趋势是使用腹腔镜手术来治疗穿孔性消化性溃疡,我们进行了这篇叙述性综述文章来调查目前治疗这种情况的趋势。
{"title":"Perforated Peptic Ulcer-Current Management: A Narrative Review","authors":"None Kumar H. R., None Soma M., None Saw M. O.","doi":"10.9734/ajmah/2023/v21i11927","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i11927","url":null,"abstract":"Perforated peptic ulcer is a complication of peptic ulcer disease with its incidence being stable despite the introduction of proton pump inhibitors. This condition is seen in older patients with comorbidities and early diagnosis improves the mortality of this condition. The treatment of perforated peptic ulcer is performed by closure of the perforated peptic ulcer, and this procedure can be performed by open or laparoscopic surgery. The current trend over the last few years has been the use of laparoscopic surgery in the management of perforated peptic ulcer and we have conducted this narrative review article to investigate the current trend in management of this condition.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135351460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Menopause-Related Domestic Violence in Bangladesh and Its Associated Factors 孟加拉国与更年期有关的家庭暴力及其相关因素
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-10-02 DOI: 10.9734/ajmah/2023/v21i11926
Md. Azim Rana, Sazin Islam, Sharmin Akter, Mst. Shamsun Naher, Md. Shariful Islam, Sonia Afroz Mukta, Sadia Afroz Rikta
Background: Menopause, a natural physiological transition, has been associated with various health and psychosocial challenges. This study aimed to explore the association between menopausal symptoms and the occurrence of domestic violence in Bangladesh, considering a range of socio-economic and demographic determinants. Methods: A cross-sectional study was conducted among 500 Bangladeshi women aged 40-60. Data were collected using structured questionnaires, and the severity of menopausal symptoms was categorized as low, moderate, and severe. Chi-Square tests were utilized to establish associations. Results: Women with severe menopausal symptoms reported the highest occurrence of domestic violence at 58%. Emotional and psychological violence was most prevalent at 55%, followed by physical violence at 42%, economic deprivation at 28%, and sexual violence at 14%. Conclusion: The study underscores the pressing need for comprehensive interventions to address domestic violence against menopausal women in Bangladesh. A holistic approach, encompassing medical, psychological, socio-economic, and educational strategies, is crucial for effective mitigation.
背景:更年期是一种自然的生理转变,与各种健康和心理社会挑战有关。考虑到一系列社会经济和人口因素,本研究旨在探讨孟加拉国绝经期症状与家庭暴力发生之间的关系。方法:对500名40-60岁的孟加拉妇女进行横断面研究。使用结构化问卷收集数据,并将更年期症状的严重程度分为轻度、中度和重度。使用卡方检验来建立关联。 结果:有严重更年期症状的妇女报告的家庭暴力发生率最高,为58%。情感和心理暴力最为普遍,占55%;其次是身体暴力,占42%;经济剥夺,占28%;性暴力,占14%。结论:该研究强调了孟加拉国迫切需要采取综合干预措施来解决针对更年期妇女的家庭暴力问题。综合医疗、心理、社会经济和教育战略的整体办法对于有效缓解至关重要。
{"title":"Menopause-Related Domestic Violence in Bangladesh and Its Associated Factors","authors":"Md. Azim Rana, Sazin Islam, Sharmin Akter, Mst. Shamsun Naher, Md. Shariful Islam, Sonia Afroz Mukta, Sadia Afroz Rikta","doi":"10.9734/ajmah/2023/v21i11926","DOIUrl":"https://doi.org/10.9734/ajmah/2023/v21i11926","url":null,"abstract":"Background: Menopause, a natural physiological transition, has been associated with various health and psychosocial challenges. This study aimed to explore the association between menopausal symptoms and the occurrence of domestic violence in Bangladesh, considering a range of socio-economic and demographic determinants.
 Methods: A cross-sectional study was conducted among 500 Bangladeshi women aged 40-60. Data were collected using structured questionnaires, and the severity of menopausal symptoms was categorized as low, moderate, and severe. Chi-Square tests were utilized to establish associations.
 Results: Women with severe menopausal symptoms reported the highest occurrence of domestic violence at 58%. Emotional and psychological violence was most prevalent at 55%, followed by physical violence at 42%, economic deprivation at 28%, and sexual violence at 14%.
 Conclusion: The study underscores the pressing need for comprehensive interventions to address domestic violence against menopausal women in Bangladesh. A holistic approach, encompassing medical, psychological, socio-economic, and educational strategies, is crucial for effective mitigation.","PeriodicalId":49491,"journal":{"name":"Southeast Asian Journal of Tropical Medicine and Public Health","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135830346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inverted Sinonasal Papilloma: Update and Literature Review 鼻窦内翻性乳头状瘤:最新进展及文献综述
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-09-30 DOI: 10.9734/ajmah/2023/v21i11925
Babatope Lanre Awosusi, Adam Tolulope Rahman
Inverted sinonasal papilloma is a benign neoplasm that usually affects the intra-nasal cavity and adjacent paranasal sinuses. Inverted papillomas have three unique features that distinguishes them from other sinonasal tumors including; a propensity for local destructive growth, a high rate of recurrence and risk of malignant transformation. The reported yearly incidence is about 0.6 to 1.5 cases per 100,000 people per year and they usually account for 0.5% to 4% of all nasal tumors. They occur at the following locations; both lateral nasal walls, ethmoidal cells, maxillary sinus, the frontal sinus, sphenoid sinuses and the nasal septum in decreasing order. It occurs most commonly in the fifth and sixth decades of life with a male-to-female ratio of 2-3:1. Inverted papilloma can arise from the entire Schneiderian membrane and molecular genetics have confirmed that it is an actual neoplasm that arises from a single progenitor cell. Most cases are diagnosed from clinical history and thorough physical examination. However, complete removal of all affected tissue with thorough histopathological evaluation is recommended to ensure a correct diagnosis. While there is yet no established pathognomonic histopathological feature to predict recurrence with all certainty, there is ongoing investigation for predictive markers of recurrence. Smoking seems to be a recognized risk factor for developing multiple recurrences and there is evidence that the presence of HPV serotypes 16 and 18 could be predictive of malignant transformation. The main aim of treatment is to achieve compete surgical resection and to prevent recurrence and malignant transformation. A period of clinical follow up is recommended after treatment. The aim of this review is to provide a comprehensive and updated overview of the clinical presentation, diagnosis, management and prognosis of this unique lesion.
鼻窦内翻性乳头状瘤是一种良性肿瘤,通常影响鼻腔内和邻近的鼻窦。内翻性乳头状瘤与其他鼻窦肿瘤有三个独特的特征,包括:有局部破坏性生长的倾向,复发率高,有恶性转化的危险。据报道,每年的发病率约为每10万人中0.6至1.5例,通常占所有鼻肿瘤的0.5%至4%。它们发生在以下地点:双侧鼻壁、筛细胞、上颌窦、额窦、蝶窦、鼻中隔依次递减。它最常见于生命的第五和第六十年,男女比例为2:3:1。倒置乳头状瘤可以发生在整个施耐德膜上,分子遗传学已经证实它是一种真正的肿瘤,起源于单个祖细胞。大多数病例是通过临床病史和彻底的体格检查来诊断的。然而,建议完全切除所有受影响的组织并进行彻底的组织病理学评估,以确保正确的诊断。虽然目前还没有确定的病理组织学特征可以完全确定地预测复发,但正在进行有关复发预测标志物的研究。吸烟似乎是一个公认的多发复发的危险因素,有证据表明,HPV血清型16和18的存在可以预测恶性转化。治疗的主要目的是达到手术完全切除,防止复发和恶性转化。建议治疗后进行一段时间的临床随访。本文综述的目的是对这种独特病变的临床表现、诊断、治疗和预后提供全面和最新的概述。
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引用次数: 1
A Rare Case of Kikuchi-Fujimoto Disease in an Indian Female 一例罕见的印度女性菊池-藤本病
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-09-29 DOI: 10.9734/ajmah/2023/v21i11923
Shubham Darda, Aarjuv Majmundar, Puneet Upadhyay, Harshita H. Nouni, Sucheta Lakhani, Jitendra D. Lakhani
Kikuchi-Fujimoto disease is a self-limiting illness characterised by non-specific symptoms, most commonly reported symptoms being fever and lymphadenopathy. Unknown in its cause, Kikuchi-Fujimoto disease (KFD) is a benign, uncommon disorder usually presenting under the age of 30 years in women. This disease is mainly seen in Asian population mainly in Japan but it is rare in Indian population. The etiological cause of this disease remains unknown. This condition needs to differentiated from other closely resembling conditions such as tuberculosis, lymphoma, Systemic Lupus Erythematosus (SLE) and adenocarcinoma. The physician needs to be aware about this condition to avoid misdiagnosis and improper treatment. This case report is about a female of age 26 years who was diagnosed as having Kikuchi Fujimoto Disease on the basis of clinical and biopsy findings.
菊池-藤本病是一种以非特异性症状为特征的自限性疾病,最常见的报告症状是发烧和淋巴结病。菊chi- fujimoto病(KFD)是一种不常见的良性疾病,病因不明,通常发生在30岁以下的女性中。此病主要见于亚洲人群,主要见于日本,但在印度人群中罕见。这种疾病的病因尚不清楚。这种情况需要与其他类似的疾病如肺结核、淋巴瘤、系统性红斑狼疮(SLE)和腺癌进行鉴别。医生需要了解这种情况,以避免误诊和治疗不当。本病例报告是关于一名26岁的女性,根据临床和活检结果被诊断为患有菊池藤本病。
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引用次数: 0
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Southeast Asian Journal of Tropical Medicine and Public Health
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