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Knowledge and Practice of Menstrual Hygiene among Female Students of Government Day Senior Secondary School (GDSSS) Tal, Billiri Local Government Area, Gombe State, Nigeria 尼日利亚贡贝州比利里地方政府区塔尔政府日高中女生的经期卫生知识与实践
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-18 DOI: 10.9734/ajmah/2023/v21i10890
Rose Mela Danjin, H. Moda, M. Danjin, P. Doka, Vivian Kelechi-Ebisike, J. Kelechi
This objective of this study was to assess the knowledge and common Menstrual Hygiene (MH) practices among female students at Government Day Secondary School (GDSS) Tal, Billiri Local Govt Area of Gombe State, Nigeria. A cross sectional descriptive study design was adopted for the study and a simple probability proportional to size (PPS) sampling technique was used to select a sample of 133 respondents out of a total of 194 female students aged 14 to 22 years, spread across all the three grades of senior secondary school students. A self-constructed 46-item instrument was used for data collection. The mean age at menarche (first menstrual period) for the girls was 14±1.24 years, and their average duration of menstrual flow was 3±1.04 days. A good majority (80.9%) of them exhibited either medium or higher level of knowledge of menstrual hygiene. This perhaps explains why majority (75.9%) of them used sanitary pad and 43.2% used new piece of cloth. Furthermore, majority (87.1%) of the girls were in the habit of changing pad/absorbent more than once in a day. Commendably, an overwhelming majority (90.8%) of them take bath two to three times a day, and 79.5% use soap and water for cleaning of their external genitalia, just as 66.4% of them impressively practice washing of their genitalia from front to back. Some of the factors that undermines menstrual hygiene as opined by the respondents include “No money to buy sanitary pad” (63.9%), “There is no privacy in school to change regularly” (60.0%), “Family only allows or affords use of tissue and cloth materials (34.6%) and “Religion forbids public places when menstruating (30.5%)”. Considering the above it is recommended that sustainable women and girlchild economic empowerment programmes and free school-based sanitary pad distribution interventions be deployed to the area of study.
本研究的目的是评估尼日利亚贡贝州比利里地方政府区塔尔政府走读中学(GDSS)女生的月经卫生知识和常见做法。本研究采用横断面描述性研究设计,采用简单概率比例抽样(PPS)方法,从194名14至22岁的女学生中抽取133名受访者,分布在高中三个年级。采用自建46项仪器进行数据采集。初潮年龄平均为14±1.24岁,月经持续时间平均为3±1.04 d。绝大多数(80.9%)的妇女对月经卫生有中等或较高的认识。这也许可以解释为什么大多数(75.9%)的人使用卫生巾,43.2%的人使用新布。此外,大多数(87.1%)的女孩有每天更换一次以上的护垫/吸收剂的习惯。值得称赞的是,绝大多数(90.8%)的人每天洗澡2 - 3次,79.5%的人使用肥皂和水清洗外生殖器,66.4%的人令人印象深刻地练习从前到后清洗生殖器。受访者认为影响经期卫生的因素包括“没有钱买卫生巾”(63.9%)、“学校没有定期更换的隐私”(60.0%)、“家庭只允许或负担卫生纸和布类材料(34.6%)”和“宗教禁止在经期去公共场所(30.5%)”。考虑到上述情况,建议将可持续的赋予妇女和女童经济权力方案和免费的学校卫生巾分发干预措施部署到研究领域。
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引用次数: 0
The Administration of Spinal or Local Anesthesia in Anal Fissure and Hemorrhoidectomy: A Comparative Literature Review 肛裂和痔疮切除术中脊髓或局部麻醉的应用:比较文献综述
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-18 DOI: 10.9734/ajmah/2023/v21i10892
Ahmed M. Ashry
The purpose of this review is to consider the risks, benefits, and prospective benefits of spinal and local anesthetic. Comparing the safest and most suitable anesthetic to utilize with each surgical technique also helps. An extremely sensitive area of the human body is the anorectal region. Although it is normally shorter than the remainder of the gastrointestinal system, measuring between 2.5 and 4 cm, it is extremely complex physically and functionally. The anal canal's only purpose is to serve as a link between the rectum and the digestive system. It is crucial for maintaining fecal continence and safeguards the body against foreign bacteria that may utilize the rectum as a possible entrance point into the anal canal. Anorectal anal fissures are a typical, benign disorder. It is an extremely painful disease that, in certain extreme situations, may also cause per rectal hemorrhage. Usually an ulcer, it develops longitudinally in the anus's epithelial lining immediately distal to the dentate line. A fissure-in-ano is characterized by indurated margins, visible internal anal sphincter fibers, and a polyp or skin tag close to the fissure's distal end. Hemorrhoids are little clusters of arteriovenous, fibrovascular, and submucosal sinusoids that are located in the anorectal area. Hemorrhoids are shown to be related with new per rectal bleeding in the patients shortly after they defecate, which is a highly distinctive pattern. In circumstances where medical therapy is ineffective, surgery has been suggested for both of these disorders. Any time surgery is scheduled, the question of selecting anesthetic arises. Although both local and spinal anesthesia are advised, studies and expert views have shown that local anesthetic has a clear advantage over spinal anesthesia. It is a popular option for many surgeons since it is successful in terms of the patient's health and is also economical.
本综述的目的是考虑脊髓和局部麻醉的风险、益处和预期益处。比较每种手术技术使用的最安全和最合适的麻醉剂也有帮助。人体的一个极其敏感的区域是肛门直肠区域。虽然它通常比胃肠道系统的其余部分短,尺寸在2.5到4厘米之间,但它在物理和功能上极其复杂。肛管的唯一作用是连接直肠和消化系统。它对于维持大便的控制和保护身体免受外来细菌的侵害是至关重要的,这些细菌可能利用直肠作为进入肛管的入口。肛肠肛裂是一种典型的良性疾病。这是一种非常痛苦的疾病,在某些极端情况下,也可能导致直肠出血。通常是一种溃疡,它纵向发展于肛门上皮衬里,紧靠齿状线远端。裂隙的特征是边缘硬化,可见肛门内括约肌纤维,靠近裂隙远端有息肉或皮赘。痔疮是位于肛门直肠区域的小簇动静脉、纤维血管和粘膜下窦。痔疮与患者排便后不久的新直肠出血有关,这是一种非常独特的模式。在药物治疗无效的情况下,建议对这两种疾病进行手术治疗。任何手术计划,选择麻醉剂的问题出现。虽然建议局部麻醉和脊髓麻醉,但研究和专家意见表明,局部麻醉明显优于脊髓麻醉。对于许多外科医生来说,这是一个受欢迎的选择,因为它在病人的健康方面是成功的,而且也是经济的。
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引用次数: 0
Parecoxib, Dezocine and Epidural Morphine for Perioperative Multimodal Analgesia in Cesarean Section: A Randomized Study 帕瑞昔布、地佐辛和硬膜外吗啡用于剖宫产术围手术期多模式镇痛的随机研究
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-14 DOI: 10.9734/ajmah/2023/v21i10888
Wen-li Zhang, Xiaoci Huang, Xiaohong Liang, J. Zhuang, Jingying Lin, Xingqing Liu, Wei-jian Chen, Xue-jie Xu, Xueping Hu, Sheng-hui Huang
Objective: To observe the effect of multimodal analgesia with single venous injection of parecoxib sodium and single epidural injection of morphine combine with dezocine intravenous infusion on the maternal pain, the adverse effects, the maternal activity and lactation and the stress response after cesarean section. Methods: The 90 cases of pregnant were randomly divided into three groups: Morphine and Dezocine (MD) group, Parecoxib sodium and Dezocine (PD) group, Parecoxib sodium, Morphine, and Dezocine (PMD) group. There were 30 cases in each group. The following three analgesic methods and their combinations were used: single epidural injection of morphine 1.5 mg, single intravenous injection of parecoxib 40 mg and intravenous analgesia with dezocine 0.5 mg/kg.  Postoperative pain, adverse effects, maternal activity and breastfeeding, and serum substance P levels were observed. Results: These were statistically significant in the differences of VAS of incision pain at 8 h and 12 h after surgery (P < 0.05), in which the VAS in PMD group were lower than that in PD group and MD group, and in which the VAS in PD group was higher than that in MD group. These were statistically significant in the differences of VAS of uterine contractile pain at 8h and 12 h after surgery (P < 0.05), in which the VAS in PMD group were lower than that in PD group and MD group, and in which the VAS in PD group was lower than that in MD group. The time of starting to get out of bed after surgery was earlier in the PMD group than in the PD and MD groups (P < 0.05). The number of steps taken by mothers within 2 days after surgery was higher in the PMD group than in the PD and MD groups (P < 0.05). The step count within two days post-surgery was higher in the PMD group than in the PD and MD groups (P < 0.05). The serum substance P levels at the end of surgery and 1 day after surgery were lower in the PMD and PD groups than in the MD group (P < 0.05). The differences in the number of breastfeeding times within two days after surgery were statistically significant among the three groups (P < 0.05), with that in the PMD group(16.27±2.71) having been higher than in the PD group(12.63±1.67)and MD group(11.03±1.81), and that in the MD group being higher than in the PD group. Conclusion: The single intravenous sodium parecoxib combined with single epidural morphine and dezocine intravenous analgesia can better reduce the incision pain and uterine contractile pain after cesarean section, promote maternal postoperative off-bed activity and breast-feeding  times to newborn.
目的:观察单次静脉注射帕瑞昔布钠和单次硬膜外注射吗啡联合地佐辛静脉输注多模式镇痛对剖宫产术后产妇疼痛、不良反应、产妇活动、泌乳及应激反应的影响。方法:将90例孕妇随机分为吗啡和地佐辛(MD)组、帕累昔布钠和地佐辛(PD)组、帕累昔布钠、吗啡和地佐辛(PMD)组。每组30例。采用吗啡单次硬膜外注射1.5 mg、帕瑞昔布单次静脉注射40 mg、地佐辛静脉镇痛0.5 mg/kg 3种镇痛方法及联合用药。观察术后疼痛、不良反应、产妇活动及母乳喂养、血清P物质水平。结果:术后8 h、12 h切口疼痛VAS评分差异均有统计学意义(P < 0.05),其中PMD组VAS低于PD组和MD组,PD组VAS高于MD组。术后8h、12h子宫收缩性疼痛VAS评分差异均有统计学意义(P < 0.05),其中PMD组VAS低于PD组和MD组,PD组VAS低于MD组。PMD组术后开始下床时间明显早于PD、MD组(P < 0.05)。PMD组术后2 d内产妇行走步数高于PD和MD组(P < 0.05)。PMD组术后2 d内步数高于PD和MD组(P < 0.05)。PMD组和PD组术后1 d血清P物质水平均低于MD组(P < 0.05)。三组术后2 d内母乳喂养次数比较,差异均有统计学意义(P < 0.05), PMD组(16.27±2.71)高于PD组(12.63±1.67)和MD组(11.03±1.81),MD组高于PD组。结论:单次静脉帕瑞昔布钠联合单次硬膜外吗啡、地唑辛静脉镇痛能较好地减轻剖宫产术后切口疼痛和子宫收缩性疼痛,促进产妇术后下床活动和新生儿母乳喂养次数。
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引用次数: 0
To Study the Carriage and Antimicrobial Sensitivity Profile of MRSA among Nursing Staff of Rural Tertiary Health Care Centre of North India 目的研究北印度农村三级卫生保健中心护理人员MRSA携带情况及抗菌药物敏感性
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-14 DOI: 10.9734/ajmah/2023/v21i10889
Ashiya Loomba, P. Grover, Amanjot Singh Nokwal, Bharti Arora
The present study is carried to determine nasal carriage of MRSA among nursing staff posted in Medicine and allied wards of a rural tertiary healthcare center in North India and antibiotic sensitivity profile of the isolated MRSA strains. Many of the carriers of MRSA harbour pathogen in areas like nares, hand surfaces, axilla and are generally asymptomatic. Colonisation in healthcare workers has increased the incidence of serious nosocomial infection wherein healthcare workers act as vectors for transmission of infection in already immuno-compromised patients. The study undertaken was a cross sectional type where in   nursing staff was analysed for nasal carriage of MRSA and antibiotic sensitivity profile of MRSA. A total of A total of 60 nursing staff members posted in medicine and allied wards were recruited in this study. A total of 34 (56.6%) were females and 26 (43.3%) were males. our study showed considerable MRSA carriage among the nurses and also reported a decreased sensitivity to commonly used drugs. Also, no resistance was detected against higher antibiotics like Vancomycin, Teicoplanin and Linezolid which points to their use in eradication of infection caused by MRSA. There is a need to strictly implement and follow the hospital infection control guidelines so as to reduce the spread of MRSA to susceptible persons.
本研究旨在确定北印度农村三级医疗中心内科和联合病房的护理人员中MRSA的鼻腔携带情况以及分离的MRSA菌株的抗生素敏感性谱。许多MRSA携带者在鼻腔、手表面、腋窝等部位携带病原体,通常无症状。卫生保健工作者的定植增加了严重医院感染的发生率,其中卫生保健工作者在已经免疫受损的患者中充当传播感染的媒介。进行的研究是横断面型,分析护理人员的MRSA鼻腔携带和MRSA的抗生素敏感性谱。本研究共招募了60名在内科及附属病房工作的护理人员。其中女性34例(56.6%),男性26例(43.3%)。我们的研究显示护士中有相当多的MRSA携带,也报告了对常用药物的敏感性下降。此外,没有检测到对万古霉素、替柯普兰和利奈唑胺等高级抗生素的耐药性,这表明它们用于根除MRSA引起的感染。有必要严格执行和遵守医院感染控制指引,以减少MRSA对易感人群的传播。
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引用次数: 0
Frequency Distribution of ABO and Rhesus Blood Group System and their Association with the Prevalence of Various Clinical Disorders among the Kashmiri Donors: “A Possible Correlation or Just Random Distribution” 克什米尔献血者ABO和恒河猴血型系统的频率分布及其与各种临床疾病患病率的关系:“可能的相关性或只是随机分布”
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-12 DOI: 10.9734/ajmah/2023/v21i10887
M. Bashir, M. Lone, Ishtiyaq Ahmad Sofi, Shabir-Ud-Din Lone
Aim: The knowledge of blood group distribution is essential for inventory management and disease trends related to different blood groups. Besides being important in blood transfusion, ABO and Rh blood group system play an important role in forensic pathology, disease susceptibility and population genetics. The aim of the present study was to determine the frequency and distribution of ABO and Rh blood groups among (Bachelor of Medicine, Bachelor of Surgery/Bachelor of Dental Surgery) students belonging to different geographical locations in the Kashmir valley, Jammu and Kashmir, India as well as the prevalence of various disorders among the students and their parents in relation to ABO and Rh blood groups. Study Design: A Comparative Study. Place and Duration of Study: Department of Physiology, Government Medical College Srinagar, Jammu and Kashmir, India. Methodology: The ABO and Rh status was determined according to the classical slide test method. The prevalence of various disorders in the students and their parents was studied by self-administered questionnaire and all the required information was collected Results: The overall prevalence of the different blood groups followed the order:  O+ > A+ ≥ B+> O->AB+>B‑.The most common prevalent disorders associated with different blood groups were diabetes, hypertension, hyperthyroidism, hypothyroidism and rheumatoid arthritis. The other less prevalent disorders associated with several blood groups were polycystic ovarian disease, gout, myopia, fatty liver, atrial septal defect, HBV infection and vitiligo. Conclusions: The results of the present and other studies indicates that if not the exact cause of disease, the individuals with different blood group antigens are susceptible to several disorders and other health problems. Further research investigations should be conducted at large scale in order to understand such possible connections between the blood groups and diseases if any such exist.
目的:了解血型分布对库存管理和不同血型相关疾病趋势至关重要。ABO和Rh血型系统除了在输血中发挥重要作用外,还在法医病理学、疾病易感性和群体遗传学中发挥重要作用。本研究的目的是确定属于印度查谟和克什米尔克什米尔山谷不同地理位置的(医学学士、外科学士/牙科外科学士)学生中ABO和Rh血型的频率和分布,以及学生及其父母中与ABO和Rh血型有关的各种疾病的患病率。研究设计:比较研究。学习地点和时间:印度查谟和克什米尔斯利那加政府医学院生理学系。方法:采用经典玻片法测定ABO、Rh血型。采用自填问卷对学生及家长进行各项疾病的患病率调查,并收集所需资料。结果:各血型的总体患病率顺序为:O+ >A +≥B+> O->AB+>B -。与不同血型相关的最常见疾病是糖尿病、高血压、甲状腺功能亢进、甲状腺功能减退和类风湿性关节炎。其他与几种血型相关的不太常见的疾病是多囊卵巢疾病、痛风、近视、脂肪肝、房间隔缺损、HBV感染和白癜风。结论:本研究和其他研究的结果表明,如果不是疾病的确切原因,具有不同血型抗原的个体易患几种疾病和其他健康问题。进一步的研究调查应该进行大规模,以便了解血型和疾病之间可能存在的联系。
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引用次数: 0
The Role of Servant Leadership is Supporting the Health Workforce during COVID 19 服务型领导的作用是在2019冠状病毒病期间支持卫生人力
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-12 DOI: 10.9734/ajmah/2023/v21i10886
Abdul-Malik Abdulai
The COVID-19 pandemic has had a profound impact on healthcare workers worldwide. These individuals have been on the front lines, risking their health and safety to care for patients. However, the emotional toll of the pandemic cannot be overlooked. Healthcare workers are not only dealing with the physical demands of their jobs but also the psychological stress and anxiety that comes with caring for patients during a global crisis. Effective leadership is crucial in every organization, however, some organizations such as healthcare need leaders who are capable of inspiration and psychological safety. This is because health workers endure so much stress and anxiety resulting from the concerns and empathic connection with their clients. Servant leadership, an emerging leadership style, is particularly suitable during crises, such as the recent COVID-19 pandemic. Servant leadership is a style that focuses on serving the needs of others and prioritizing their well-being. This leadership approach is particularly suited to the healthcare industry, where the well-being of patients and staff is of utmost importance. Servant leaders create a culture of psychological safety, where healthcare workers feel supported and valued. This includes ensuring that healthcare workers have access to personal protective equipment, providing emotional support and counselling services, and recognizing and appreciating their efforts. To put the effect of servant leadership into perspective, this article highlights some effects of COVID-19 on health workers and follows up to present a view on how servant leaders would mitigate the effects on the workers. Current and future managers of the healthcare system should undertake training on servant leadership to serve the workers well for the ultimate benefit of the organization.
COVID-19大流行对全世界的卫生保健工作者产生了深远影响。这些人一直站在第一线,冒着健康和安全的风险照顾病人。然而,这种流行病给人们造成的情感损失不容忽视。医护人员不仅要应对工作的体力要求,还要应对在全球危机期间照顾病人所带来的心理压力和焦虑。有效的领导在每个组织中都是至关重要的,然而,一些组织,如医疗保健,需要能够激励和心理安全的领导者。这是因为卫生工作者承受了如此多的压力和焦虑,这是由于与客户的关切和共情联系造成的。仆人式领导是一种新兴的领导风格,尤其适用于危机期间,例如最近的COVID-19大流行。仆人式领导是一种专注于服务他人需求并优先考虑他人福祉的领导风格。这种领导方法特别适用于医疗保健行业,在该行业中,患者和员工的福祉至关重要。仆人式领导创造了一种心理安全的文化,在这种文化中,卫生保健工作者感到得到支持和重视。这包括确保卫生保健工作者获得个人防护装备,提供情感支持和咨询服务,并承认和赞赏他们的努力。为了正确看待服务型领导的影响,本文重点介绍了COVID-19对卫生工作者的一些影响,并就服务型领导如何减轻对卫生工作者的影响提出了看法。当前和未来的医疗保健系统管理人员应该接受仆人式领导的培训,以更好地为员工服务,为组织的最终利益服务。
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引用次数: 0
Sigmoid Volvulus: A Narrative Review and Current Management 乙状结肠扭转:叙述回顾与当前管理
4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-11 DOI: 10.9734/ajmah/2023/v21i10885
H. R. Kumar, M. Soma
Sigmoid volvulus is a common cause of acute intestinal obstruction in older patients and the diagnosis is made by clinical examination and imaging. Sigmoid volvulus can be divided into complicated or uncomplicated clinical presentation. Once the diagnosis of sigmoid volvulus is made, the treatment is initially endoscopic decompression followed by flatus tube insertion. This is followed by surgical intervention which is sigmoid colectomy followed by anastomosis. For complicated sigmoid volvulus, the Hartmann’s procedure is the most common operation. We have conducted this review article to review the current management of sigmoid volvulus.
乙状结肠扭转是老年患者急性肠梗阻的常见病因,主要通过临床检查和影像学诊断。乙状结肠扭转的临床表现可分为复杂型和非复杂型。一旦诊断为乙状结肠扭转,治疗首先是内窥镜减压,然后插入胀气管。接下来是手术干预,乙状结肠切除术,然后吻合。对于复杂的乙状结肠扭转,Hartmann手术是最常用的手术。我们进行了这篇综述文章来回顾乙状结肠扭转的治疗现状。
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引用次数: 0
Comparison of Ketamine, Clonidine, and Fentanyl as Anesthetics in the Pediatric Population: A Review of Literature 氯胺酮、可乐定和芬太尼作为儿科麻醉药的比较:文献综述
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-10 DOI: 10.9734/ajmah/2023/v21i10884
Wael Waheed Mohamed
This literature review examines the evidence on the safety profile and effectiveness of various adjuncts, such as clonidine, fentanyl, and ketamine, in pediatric anesthesia. Several studies were reviewed to evaluate the duration and quality of analgesia provided by these adjuncts, as well as their adverse effects. The results showed that adding clonidine to bupivacaine significantly prolonged the mean duration of analgesia compared to the fentanyl and clonidine groups. Children in the clonidine group also experienced lower pain scores and required fewer rescue medications. Furthermore, clonidine exhibited a higher safety margin with a lower incidence of adverse effects, such as urinary retention and pruritus, compared to other adjuncts. Regarding comparisons between fentanyl and clonidine, intrathecal fentanyl resulted in a better hemodynamic profile but required more propofol for sedation. On the other hand, intrathecal clonidine provided a more favorable sedation level. Adverse events like respiratory obstruction and apnea were more likely associated with deep sedation caused by propofol rather than the specific properties of clonidine or fentanyl. In terms of ketamine versus clonidine, caudal blocks using ketamine were found to prolong postoperative anesthesia, particularly for lower limb and abdominal surgeries. When comparing the duration of caudal analgesia achieved by bupivacaine combined with different adjuncts, ketamine exhibited a longer duration compared to clonidine and adrenaline. However, ketamine use was found to be linked with a greater incidence of adverse effects, including urinary retention and pruritus. In conclusion, clonidine demonstrated a relatively higher safety margin with prolonged analgesic effects in pediatric anesthesia compared to fentanyl and ketamine. Its addition to local anesthetics resulted in extended analgesia duration and reduced rescue medication requirements without significant side effects. However, careful monitoring is necessary to manage potential adverse effects.
本文献综述探讨了小儿麻醉中各种辅助药物的安全性和有效性的证据,如可乐定、芬太尼和氯胺酮。我们回顾了几项研究,以评估这些辅助药物提供的镇痛持续时间和质量,以及它们的不良反应。结果表明,与芬太尼组和可乐定组相比,在布比卡因中加入可乐定可显著延长平均镇痛时间。可乐定组的孩子也经历了更低的疼痛评分,需要更少的抢救药物。此外,与其他辅助药物相比,可乐定具有更高的安全边际和更低的不良反应发生率,如尿潴留和瘙痒。关于芬太尼和克拉定的比较,鞘内芬太尼导致更好的血流动力学特征,但需要更多的异丙酚镇静。另一方面,鞘内可乐定提供了更有利的镇静水平。呼吸阻塞和呼吸暂停等不良事件更可能与丙泊酚引起的深度镇静有关,而不是与氯定或芬太尼的特殊性质有关。在氯胺酮与可乐定的对比中,氯胺酮的尾侧阻滞被发现可以延长术后麻醉时间,尤其是下肢和腹部手术。当比较布比卡因联合不同佐剂对尾侧镇痛的持续时间时,氯胺酮比可乐定和肾上腺素的持续时间更长。然而,氯胺酮的使用被发现与更大的不良反应发生率有关,包括尿潴留和瘙痒。综上所述,与芬太尼和氯胺酮相比,可乐定在小儿麻醉中具有较高的安全裕度和较长的镇痛效果。局部麻醉剂的加入延长了镇痛时间,减少了救援药物的需求,没有明显的副作用。然而,仔细监测是必要的,以管理潜在的不利影响。
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引用次数: 0
D-Dimer: A Primer Biomarker in COVID-19 d -二聚体:新冠病毒的引物生物标志物
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-09 DOI: 10.9734/ajmah/2023/v21i10883
N. Chawda, Suresh Jain, Bhagirath B. Solanki, Chetan Sonkar, Simran K. Arora, Sukruti Shah, V. Tejani, Jyot Kaur Chawla, Mukesh C. Chaudhari, Ravi Chaudhari, A. Bhattacharya
Aim and Objective: To explore risk factors associated with mortality in COVID-19 patients and assess the use of D-dimer as a first line biomarker for disease severity and clinical outcome. Materials and Methods: We retrospectively analysed the pathological and radiological characteristics of 2087 consecutive cases of COVID-19 in PSH, Vadodara, Gujarat, from March 2021 to July 2022. Graphically, MS-Excel with median values were used. Correlations of D-dimer upon admission with disease severity and in-hospital mortality were analysed accordingly. Data were collected in MS-Excel with median values. Results: 2087 patients having positive RT-PCR and confirm diagnosis of Covid-19 were included upon hospital admission. Whereas, 65.78% (n= 1373) were male and 34.21% (n= 714) were female. Mean age was 52± 4 year. D-dimer level > 250 ng/mL at the time of hospital admission was the only fluctuating value accompanying with increased mortality [(95% CI), P = 0.025]. D-dimer elevation (≥250 ng/mL) was seen in 81.31% patients. Pericardial effusion and Deep vein thrombosis were ruled out in probability of thrombosis based on 2-D echo, X-ray chest and USG. This recommend that hyper-coagulopathy of the fibrin plays a significant role in the occurrence of thromboembolic complications with COVID-19 patients. D-dimer levels was crucially escalated with increasing severity of COVID-19 as determined by clinical improvement (within 5 days of hospital stay) and chest CT staging (CO-RADS score out of 25, P = 0.000). 319 patient were died during above said period and overall in-hospital mortality rate was 15.28%. Additionally, 6.08 % (n=127) patient were on BIPEP and all are died with 100% death ratio. Median D-dimer level in non-survivors (15.29%) was significantly higher than in survivors (84.71%, n = 1768, RR 24.69%). Median elevated D-dimer level was 600.5 ng/ml. Furthermore, the disease activity were higher in the overhead D-dimer level group demonstrated to have anticipating value in differentiating disease severity along with high ESR level and hs-CRP and the fibrinogen level was also upraised indicated seriousness of disease. Conclusion: We concluded that D-dimer level was routinely uplifted in patients with COVID-19 disease. D-dimer levels match up with severity of the disease and are a significant definitive prognostic first line marker for in-hospital mortality for COVID-19 disease. Furthermore, a significant association between the high D-dimer level and severity of COVID-19 disease was noted among comorbid patients. Additionally, raced D-dimer level demonstrated with high ESR level and hs-CRP and the fibrinogen level indicated seriousness of disease in comorbid patients.
目的和目的:探讨与COVID-19患者死亡率相关的危险因素,并评估d -二聚体作为疾病严重程度和临床结局的一线生物标志物的使用。材料和方法:回顾性分析2021年3月至2022年7月在古吉拉特邦瓦多达拉PSH连续发生的2087例COVID-19病例的病理和放射学特征。图形上使用MS-Excel中位数。据此分析入院时d -二聚体与疾病严重程度和住院死亡率的相关性。数据采用MS-Excel统计,采用中位数。结果:2087例患者入院时RT-PCR阳性并确诊为新冠肺炎。男性占65.78% (n= 1373),女性占34.21% (n= 714)。平均年龄52±4岁。入院时d -二聚体水平> 250 ng/mL是唯一伴随死亡率增加的波动值[95% CI), P = 0.025]。81.31%的患者出现d -二聚体升高(≥250 ng/mL)。经二维超声、胸部x线及USG检查,排除心包积液及深静脉血栓形成的可能性。这表明纤维蛋白的高凝功能在COVID-19患者血栓栓塞并发症的发生中起重要作用。d -二聚体水平随着COVID-19严重程度的增加而显著升高,这是由临床改善(住院5天内)和胸部CT分期(CO-RADS评分,P = 0.000)确定的。死亡319例,住院总死亡率15.28%。有6.08% (n=127)患者接受BIPEP治疗,全部死亡,死亡率为100%。非幸存者中位d -二聚体水平(15.29%)显著高于幸存者(84.71%,n = 1768, RR 24.69%)。d -二聚体中位升高为6000.5 ng/ml。此外,头顶d -二聚体水平组的疾病活动度较高,ESR和hs-CRP水平较高,对疾病严重程度有预测价值,纤维蛋白原水平也升高,表明疾病严重程度较高。结论:我们认为d -二聚体水平在COVID-19患者中呈常规升高。d -二聚体水平与疾病的严重程度相匹配,是COVID-19疾病住院死亡率的重要明确预后一线标志物。此外,在合并症患者中,高d -二聚体水平与COVID-19疾病严重程度之间存在显著关联。此外,高d -二聚体水平表明高ESR水平和hs-CRP,纤维蛋白原水平表明合并症患者疾病的严重程度。
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引用次数: 0
Daily Food Hygiene Relationship with Acute Diarrhea among Medical Students of UKI 大学医学院学生日常食品卫生与急性腹泻的关系
IF 0.2 4区 医学 Q4 INFECTIOUS DISEASES Pub Date : 2023-08-04 DOI: 10.9734/ajmah/2023/v21i10882
Wiradi Suryanegara, Christine Handayani Tampubolon, Randolph Serep Marantuan
Diarrhea is defecation with excrete, liquid, or semi-liquid (semi-solid); the water content of stools is more than normal, more than 200 g or 200 ml / 24 hours. Another definition using frequency criteria, the definition is watery stools more than three times per day. Acute diarrhea is diarrhea that is less than 14 days. The cause of diarrhea may include infection, food poisoning, and allergies. This study aims to analyze the relationship between daily food hygiene and acute diarrhea in Medical Students of UKI who live at boarding house. This type of research is analytic - cross-sectional. The population in this study is the student of the medical students of UKI. Determination of the sample in this study was done by probability sampling by using simple random sampling; a total of 100 boarding students living around the UKI were sampled. This study showed that of the 100 students living in boarding houses, 70 had suffered from diarrhea, and the other 30 had never experienced diarrhea. Of 100 students who assessed where they obtained food in a clean state, 26 people assessed the state where they obtained food less clean than 70 people, and the remaining four rated not clean. It is concluded that there is no relationship between everyday food hygiene with acute diarrhea in Medical Students of UKI who live at boarding house.
腹泻是带排泄物、液体或半液体(半固体)的排便;大便含水量超过正常,超过200克或200毫升/ 24小时。另一种使用频率标准的定义是每天大便超过三次。急性腹泻是指持续时间少于14天的腹泻。腹泻的原因可能包括感染、食物中毒和过敏。本研究旨在分析寄宿学校医学生日常饮食卫生与急性腹泻的关系。这种类型的研究是分析性的——横断面的。本研究的人群是UKI医学院学生的学生。本研究样本的确定采用概率抽样,采用简单随机抽样;总共有100名住在大学附近的寄宿学生被抽样调查。这项研究表明,住在寄宿公寓的100名学生中,70人患有腹泻,另外30人从未患过腹泻。在100名评估他们在清洁状态下获得食物的学生中,26人评估他们获得的食物不太干净的状态,其余4人评估不干净的状态。结论:寄宿学校医学生日常饮食卫生与急性腹泻无关系。
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引用次数: 0
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Southeast Asian Journal of Tropical Medicine and Public Health
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