Fingerprint based human identification is one of the authentic biometric recognition systems due to the permanence and uniqueness of the finger impressions. There is the extensive usage of fingerprint recognition in personalized electronic devices, security systems, banking, forensic labs, and especially in law enforcement agencies. Although the existing systems can recognize fingerprints, they lack in case of poor quality and latent fingerprints. The latent fingerprints are captured by law enforcement agencies during the crime scene to find the criminal. Consequently, it is essential to develop a novel system that can efficiently recognize both complete and latent fingerprints. The current work proposes an efficient Gravitational Search Decision Forest (GSDF) method, which is a combination of the gravitational search algorithm (GSA) and the random forest (RF) method. In the proposed GSDF approach, the mass agent of GSA determines the solution by constructing decision trees in accordance with the random forest hypothesis. The recognition of the fingerprints is accomplished by mass agents in the form of a final generated decision forest from the set of hypothesis space as the mass agents can create multiple hypotheses using random proportional rules. The experiments for fingerprint recognition are conducted for both the latent fingerprints (NIST SD27 dataset) and the complete fingerprints (FVC2004 dataset). The effectiveness of the proposed GSDF approach is analyzed by evaluating the results with machine learning classifiers (random forest, decision tree, back propagation neural networks, and k-nearest neighbor) as well. The comparative analysis of the proposed approach and incorporated machine learning classifiers indicates the outperformed performance of the proposed approach.
{"title":"An Efficient Gravitational Search Decision Forest Approach for Fingerprint Recognition","authors":"Mahesh Kumar, Devender Kumar","doi":"10.48129/kjs.20635","DOIUrl":"https://doi.org/10.48129/kjs.20635","url":null,"abstract":"Fingerprint based human identification is one of the authentic biometric recognition systems due to the permanence and uniqueness of the finger impressions. There is the extensive usage of fingerprint recognition in personalized electronic devices, security systems, banking, forensic labs, and especially in law enforcement agencies. Although the existing systems can recognize fingerprints, they lack in case of poor quality and latent fingerprints. The latent fingerprints are captured by law enforcement agencies during the crime scene to find the criminal. Consequently, it is essential to develop a novel system that can efficiently recognize both complete and latent fingerprints. The current work proposes an efficient Gravitational Search Decision Forest (GSDF) method, which is a combination of the gravitational search algorithm (GSA) and the random forest (RF) method. In the proposed GSDF approach, the mass agent of GSA determines the solution by constructing decision trees in accordance with the random forest hypothesis. The recognition of the fingerprints is accomplished by mass agents in the form of a final generated decision forest from the set of hypothesis space as the mass agents can create multiple hypotheses using random proportional rules. The experiments for fingerprint recognition are conducted for both the latent fingerprints (NIST SD27 dataset) and the complete fingerprints (FVC2004 dataset). The effectiveness of the proposed GSDF approach is analyzed by evaluating the results with machine learning classifiers (random forest, decision tree, back propagation neural networks, and k-nearest neighbor) as well. The comparative analysis of the proposed approach and incorporated machine learning classifiers indicates the outperformed performance of the proposed approach.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"383 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80727308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-28DOI: 10.48129/kjs.splcov.19499
Maha Abujazar, S. Al-Awadhi, Mustapha Rachdi, H. Bensmail
Background: COVID-19 has emerged as a serious pandemic that emerged during since the end of 2019. The dissemination and survival of coronaviruses have been demonstrated to be affected by ambient temperature in epidemiological and laboratory research. The goal of this investigation was to see if temperature plays a role in Methods: Between March 29, 2020, and September 29, 2020, daily confirmed cases and meteoro-logical parameters in many Gulf countries were collected. Using a generalized additive model, we investigated the nonlinear relationship between mean temperature and COVID-19 confirmed cases.. To further investigate the association, we employed a piecewise linear regression. Results: According to the exposure-response curves, the association between mean temperature and COVID-19 cases was nearly linear in the window of 21-30degreeC while it is almost flat beyond that window. When the number was below 21degreeC (lag 0-14), each 1degreeC increase was associated with a 4:861 percent (95 percent CI: 3:209 6:513) increase in mean temperature (lag 0-14). Our sensitiv-ity analysis confirmed these conclusions. Conclusions: Our findings show a positive linear association between mean temperature and the number of COVID-19 cases with a threshold of 21degreeC. There is little evidence that COVID-19 case numbers would rise as the weather becomes colder, which has important consequences for making health strategy and decision.
{"title":"Effect of temperature on the spread of Covid-19 in Qatar, Kuwait and other Gulf countries","authors":"Maha Abujazar, S. Al-Awadhi, Mustapha Rachdi, H. Bensmail","doi":"10.48129/kjs.splcov.19499","DOIUrl":"https://doi.org/10.48129/kjs.splcov.19499","url":null,"abstract":"Background: COVID-19 has emerged as a serious pandemic that emerged during since the end of 2019. The dissemination and survival of coronaviruses have been demonstrated to be affected by ambient temperature in epidemiological and laboratory research. The goal of this investigation was to see if temperature plays a role in Methods: Between March 29, 2020, and September 29, 2020, daily confirmed cases and meteoro-logical parameters in many Gulf countries were collected. Using a generalized additive model, we investigated the nonlinear relationship between mean temperature and COVID-19 confirmed cases.. To further investigate the association, we employed a piecewise linear regression. Results: According to the exposure-response curves, the association between mean temperature and COVID-19 cases was nearly linear in the window of 21-30degreeC while it is almost flat beyond that window. When the number was below 21degreeC (lag 0-14), each 1degreeC increase was associated with a 4:861 percent (95 percent CI: 3:209 6:513) increase in mean temperature (lag 0-14). Our sensitiv-ity analysis confirmed these conclusions. Conclusions: Our findings show a positive linear association between mean temperature and the number of COVID-19 cases with a threshold of 21degreeC. There is little evidence that COVID-19 case numbers would rise as the weather becomes colder, which has important consequences for making health strategy and decision.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89901491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nano Electro Mechanical System (NEMS) based cantilever is the alternate form of Micro Electro Mechanical system (MEMS) with dimensional changes in perspectives like thickness, length, and width. The advantage of the dimensional change leads to great improvement in sensitivity and performance with portable structure. In this paper, a stepped nanocantilever sensor is designed for the detection of volatile organic compounds. The same is compared with the conventional micro cantilevers in order to assess the sensitivity. The advantage of incorporating longitudinal cut at fixed end of the cantilever is investigated for different materials with load analysis and stress distributed results. COMSOL Simulation software is used to perform the analysis of nanocantilever and the result shows sensitivity increased with longitudinal cut and type of material which exhibits good sensitivity. In this research, we suggest a stepped cantilever structure that uses FEM (Finite Element Method) of analysis to calculate the change in deflection owing to various loads in both static and dynamic analyses. Similarly, changes in resonance frequency for changes in beam thickness are examined using parametric study. The experimental results from COMSOL simulation are found that the displacement occurred in proposed cantilever that the deflection sensitivity 2.85 x10-9m under maximum stress of 3.32 x10-9 N/m2. From the dynamic analysis, resonant frequency occurs at 20nm thickness is 2.8x107 Hz, and at 30nm is 3.5 x 107 Hz respectively.
{"title":"Sensitivity Analysis of NEMS Cantilever to Detect Volatile Organic Compounds Using Finite Element Method","authors":"C. Jayaprakash, Dr N Siddaiah","doi":"10.48129/kjs.20501","DOIUrl":"https://doi.org/10.48129/kjs.20501","url":null,"abstract":"Nano Electro Mechanical System (NEMS) based cantilever is the alternate form of Micro Electro Mechanical system (MEMS) with dimensional changes in perspectives like thickness, length, and width. The advantage of the dimensional change leads to great improvement in sensitivity and performance with portable structure. In this paper, a stepped nanocantilever sensor is designed for the detection of volatile organic compounds. The same is compared with the conventional micro cantilevers in order to assess the sensitivity. The advantage of incorporating longitudinal cut at fixed end of the cantilever is investigated for different materials with load analysis and stress distributed results. COMSOL Simulation software is used to perform the analysis of nanocantilever and the result shows sensitivity increased with longitudinal cut and type of material which exhibits good sensitivity. In this research, we suggest a stepped cantilever structure that uses FEM (Finite Element Method) of analysis to calculate the change in deflection owing to various loads in both static and dynamic analyses. Similarly, changes in resonance frequency for changes in beam thickness are examined using parametric study. The experimental results from COMSOL simulation are found that the displacement occurred in proposed cantilever that the deflection sensitivity 2.85 x10-9m under maximum stress of 3.32 x10-9 N/m2. From the dynamic analysis, resonant frequency occurs at 20nm thickness is 2.8x107 Hz, and at 30nm is 3.5 x 107 Hz respectively.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88272047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Iqbal, Shazia Abrar, A. Mukhtar, Irfan Ahmad, Muhammad Zawar Khan
N'',N'''-Bis[(E)-phenylmethylidene]carbonic dihydrazide, azotic ligands with lone electron pairs, have wide range of applications in catalysis, medicine, corrosion, and analytical chemistry. Keeping this broad range of applications in view, we have developed a new green method for the rapid synthesis of N'',N'''-Bis[(E)-phenylmethylidene]carbonic dihydrazide and its derivatives. By using a new protocol, a range of carbonic dihydrazides 1-22 has been synthesized in excellent yields. All synthesized compounds have been characterized by elemental analyses, 1H-NMR, EI-MS and HR-MS. These carbonic dihydrazides have also been synthesized via conventional method. On comparisons of new and conventional methods, it is evident that newly developed solvent-free method is more proficient, high yielding, and simple. As protease inhibitors are known to inhibit not only proliferation of cancer cell lines but also to cure hepatitis C virus and HIV aids infections, therefore, all purified and characterized compounds have also been evaluated for their potential to act as in vitro α-chymotrypsin (an enzyme belongs to protease family) inhibitors. Among tested compounds, ten compounds have shown varying degree of α-chymotrypsin inhibition potential.
{"title":"An Efficient Synthesis of N'',N'''-Bis[(E)-phenylmethylidene]carbonic Dihydrazide Derivatives and Their Evaluation as α-Chymotrypsin Inhibitors","authors":"S. Iqbal, Shazia Abrar, A. Mukhtar, Irfan Ahmad, Muhammad Zawar Khan","doi":"10.48129/kjs.19975","DOIUrl":"https://doi.org/10.48129/kjs.19975","url":null,"abstract":"N'',N'''-Bis[(E)-phenylmethylidene]carbonic dihydrazide, azotic ligands with lone electron pairs, have wide range of applications in catalysis, medicine, corrosion, and analytical chemistry. Keeping this broad range of applications in view, we have developed a new green method for the rapid synthesis of N'',N'''-Bis[(E)-phenylmethylidene]carbonic dihydrazide and its derivatives. By using a new protocol, a range of carbonic dihydrazides 1-22 has been synthesized in excellent yields. All synthesized compounds have been characterized by elemental analyses, 1H-NMR, EI-MS and HR-MS. These carbonic dihydrazides have also been synthesized via conventional method. On comparisons of new and conventional methods, it is evident that newly developed solvent-free method is more proficient, high yielding, and simple. As protease inhibitors are known to inhibit not only proliferation of cancer cell lines but also to cure hepatitis C virus and HIV aids infections, therefore, all purified and characterized compounds have also been evaluated for their potential to act as in vitro α-chymotrypsin (an enzyme belongs to protease family) inhibitors. Among tested compounds, ten compounds have shown varying degree of α-chymotrypsin inhibition potential.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73916551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pseudomonas aeruginosa is the most frequent nosocomial pathogen, causing many infections in people and posing significant health risks worldwide. The current work attempts to understand the connection between antibiotic resistance genes (ARG), virulence factors (VF), and insertion sequences (IS) in P. aeruginosa. Fifty-six P. aeruginosa complete plasmids were retrieved from the NCBI database for this investigation. The CARD and Resfinder tools are used to discover ARG in P. aeruginosa. The VF analyzer and ISsaga tools are used to identify virulence genes and insertion sequences in the sorted plasmids. Using the tool PHASTER, the participation of prophage and integrase genes was discovered. Resistance to sulfonamide and beta-lactam was the most common ARG among the plasmids. Fil, pil, and XCP secretion systems are prevalent virulence genes. The prophage, integrase, and transposons were also identified. The correlation analysis of ARG, VF, and IS revealed that ISs, rather than virulence factors, had the most significant effect on the P. aeruginosa genome studied. As a result, an understanding of infectious bacterial profiles regarding pathogenicity islands and mobile elements is required to gain knowledge of their distribution and limit their spread throughout the world.
{"title":"Insilico analysis on the complex relationship among antibiotic resistance, virulence genes and insertion sequences in Pseudomonas aeruginosa","authors":"Santhiya Kalimuthu","doi":"10.48129/kjs.14591","DOIUrl":"https://doi.org/10.48129/kjs.14591","url":null,"abstract":"Pseudomonas aeruginosa is the most frequent nosocomial pathogen, causing many infections in people and posing significant health risks worldwide. The current work attempts to understand the connection between antibiotic resistance genes (ARG), virulence factors (VF), and insertion sequences (IS) in P. aeruginosa. Fifty-six P. aeruginosa complete plasmids were retrieved from the NCBI database for this investigation. The CARD and Resfinder tools are used to discover ARG in P. aeruginosa. The VF analyzer and ISsaga tools are used to identify virulence genes and insertion sequences in the sorted plasmids. Using the tool PHASTER, the participation of prophage and integrase genes was discovered. Resistance to sulfonamide and beta-lactam was the most common ARG among the plasmids. Fil, pil, and XCP secretion systems are prevalent virulence genes. The prophage, integrase, and transposons were also identified. The correlation analysis of ARG, VF, and IS revealed that ISs, rather than virulence factors, had the most significant effect on the P. aeruginosa genome studied. As a result, an understanding of infectious bacterial profiles regarding pathogenicity islands and mobile elements is required to gain knowledge of their distribution and limit their spread throughout the world.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81000073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Kareem, A. Saeed, Mahasin F. Hadi Al- Kadhemy, F. Kadhum
Energy transfer in a hybrid mixture of Rhodamine 6G (Rh6G) dye laser as a donor and nanoparticles (NPs) as an acceptor were studied. The absorption spectra of 1×10-5M of Rh6G in Distilled Water show increase in the intensity when adding NPs. noticeable, improve the spectra when adding Aluminum Oxide Al2O3 NPs. Adding NPs quench the fluorescence spectra of Rh6G due to Förster resonance energy transfer (FRET). The efficiency of energy transfer increase with increasing concentration of NPs. Best value of efficiency of energy transfer found in Rh6G/ Magnesium Oxide MgO NPs. Strong relationship was in Rh6G/ Al2O3 NPs.
{"title":"The Effect of Mixing Nanoparticles on the Suspension Physical Stability","authors":"F. Kareem, A. Saeed, Mahasin F. Hadi Al- Kadhemy, F. Kadhum","doi":"10.48129/kjs.17831","DOIUrl":"https://doi.org/10.48129/kjs.17831","url":null,"abstract":"Energy transfer in a hybrid mixture of Rhodamine 6G (Rh6G) dye laser as a donor and nanoparticles (NPs) as an acceptor were studied. The absorption spectra of 1×10-5M of Rh6G in Distilled Water show increase in the intensity when adding NPs. noticeable, improve the spectra when adding Aluminum Oxide Al2O3 NPs. Adding NPs quench the fluorescence spectra of Rh6G due to Förster resonance energy transfer (FRET). The efficiency of energy transfer increase with increasing concentration of NPs. Best value of efficiency of energy transfer found in Rh6G/ Magnesium Oxide MgO NPs. Strong relationship was in Rh6G/ Al2O3 NPs.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84339472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Four novel proton transfer compounds (1-4) obtained between 2-aminopyridine (1), 2-amino-4-methylpyridine (2), 2-amino-5-methylpyridine (3), 2-amino-6-methylpyridine (4) and 2,4-dichloro-5-sulfamoylbenzoic acid (Hsba) and their Cu(II) complexes (6-10) have been synthesized. The structures of powdery salts (1-4) and complexes (6-10) have been suggested by spectral (1H-NMR, FT-IR and UV–Vis), elemental analysis, AAS, molar conductivity and magnetic susceptibility techniques of 6-10 have also been reported. The structures of metal complexes (6-10) were observed octahedral according to spectroscopic analysis results. Additionally, anti-microbial and anti-fungal activities of all compounds have been tested against Escherichia coli (ATCC 25922) (Gram negative), Enterococcus faecalis (ATCC 29212) (Gram positive), Staphylococcus aureus (ATCC 29213) (Gram positive), and Candida Albicans (ATCC 14053) (yeast), Candida parapisilosis (ATCC 22019) (yeast), and Candida krusei (ATCC 6258) (yeast). The results were comparisoned with the antibiotics, Fluconazole as anti-fungal agent and Cefepime, Levofloxacin, Vancomycin as anti-microbial agents. Activity against all compounds bacteria and yeasts was observed. Therefore, all compounds may be utilized for the synthesis of new anti-microbial and anti-fungal. Compounds with the best activity are 2 (15.60) for S. aureus, 2, 8 and 11 (31.25) for E. Faecalis, 2a5mp, 1, 2 and 9 (31.25) for E. Coli, Cu(OAc)2.2H2O, 1, 2 and 9 (31.25) for C. Parapsilosis, Hsba (15.60) for C. Albicans and Hsba and 8 (31.25) for C. Krusei.
{"title":"Synthesis, characterization, anti-microbial and anti-fungal activity studies of four novel 2-aminopyridine and 2,4-dichloro-5-sulfamoylbenzoic acid salts and their Cu(II) complexes","authors":"H. İlkimen, Aysel Gülbandilar","doi":"10.48129/kjs.19163","DOIUrl":"https://doi.org/10.48129/kjs.19163","url":null,"abstract":"Four novel proton transfer compounds (1-4) obtained between 2-aminopyridine (1), 2-amino-4-methylpyridine (2), 2-amino-5-methylpyridine (3), 2-amino-6-methylpyridine (4) and 2,4-dichloro-5-sulfamoylbenzoic acid (Hsba) and their Cu(II) complexes (6-10) have been synthesized. The structures of powdery salts (1-4) and complexes (6-10) have been suggested by spectral (1H-NMR, FT-IR and UV–Vis), elemental analysis, AAS, molar conductivity and magnetic susceptibility techniques of 6-10 have also been reported. The structures of metal complexes (6-10) were observed octahedral according to spectroscopic analysis results. Additionally, anti-microbial and anti-fungal activities of all compounds have been tested against Escherichia coli (ATCC 25922) (Gram negative), Enterococcus faecalis (ATCC 29212) (Gram positive), Staphylococcus aureus (ATCC 29213) (Gram positive), and Candida Albicans (ATCC 14053) (yeast), Candida parapisilosis (ATCC 22019) (yeast), and Candida krusei (ATCC 6258) (yeast). The results were comparisoned with the antibiotics, Fluconazole as anti-fungal agent and Cefepime, Levofloxacin, Vancomycin as anti-microbial agents. Activity against all compounds bacteria and yeasts was observed. Therefore, all compounds may be utilized for the synthesis of new anti-microbial and anti-fungal. Compounds with the best activity are 2 (15.60) for S. aureus, 2, 8 and 11 (31.25) for E. Faecalis, 2a5mp, 1, 2 and 9 (31.25) for E. Coli, Cu(OAc)2.2H2O, 1, 2 and 9 (31.25) for C. Parapsilosis, Hsba (15.60) for C. Albicans and Hsba and 8 (31.25) for C. Krusei.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90218098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes mellitus (DM), a heterogeneous metabolic disorder, affect people at any point of their lives. Globally, a wide variation in the prevalence of diabetes was observed but, showed zero percent within people that regularly consume camel milk because of their highly nutritional and therapeutic potentials to treat many metabolic and autoimmune diseases. The present study validated the efficacy of camel milk by investigating the differential hypoglycemic effects in concurrence with related biochemical tests in rats fed with raw and pasteurized milk of the one-humped Arabian camel (Camelus dromedarius). Male Sprague-Dawley rats (60mg.Kg-1 body weight) fed separately with raw and pasteurized camel milk for three weeks and injected with streptozotocin induced DM besides the investigation on the levels of blood glucose, cholesterol, triacylglycerol (TAG), and insulin. Results showed a significant hypoglycemic effect with both raw and pasteurized camel milk but, more prominent with the raw milk. Three weeks consumption of raw camel milk significantly increased blood cholesterol levels while consumption of pasteurized camel milk caused the reverse. Both types of camel milk revealed significant decrease in the blood TAG levels and were statistically validated. Thus, the present study recommends the choice of camel milk consumption especially in diabetic patients as well, as an immunity booster in the wake of the present environmental health issues.
{"title":"Congruent Assessment of human hypoglycemic effect through STZ-Induced Diabetic rats fed Dromedary Camel (Camelus dromedarius) milk","authors":"Sirar A. Baker, Amal M. Al‐Saffar, M. Al-Sughayer","doi":"10.48129/kjs.16777","DOIUrl":"https://doi.org/10.48129/kjs.16777","url":null,"abstract":"Diabetes mellitus (DM), a heterogeneous metabolic disorder, affect people at any point of their lives. Globally, a wide variation in the prevalence of diabetes was observed but, showed zero percent within people that regularly consume camel milk because of their highly nutritional and therapeutic potentials to treat many metabolic and autoimmune diseases. The present study validated the efficacy of camel milk by investigating the differential hypoglycemic effects in concurrence with related biochemical tests in rats fed with raw and pasteurized milk of the one-humped Arabian camel (Camelus dromedarius). Male Sprague-Dawley rats (60mg.Kg-1 body weight) fed separately with raw and pasteurized camel milk for three weeks and injected with streptozotocin induced DM besides the investigation on the levels of blood glucose, cholesterol, triacylglycerol (TAG), and insulin. Results showed a significant hypoglycemic effect with both raw and pasteurized camel milk but, more prominent with the raw milk. Three weeks consumption of raw camel milk significantly increased blood cholesterol levels while consumption of pasteurized camel milk caused the reverse. Both types of camel milk revealed significant decrease in the blood TAG levels and were statistically validated. Thus, the present study recommends the choice of camel milk consumption especially in diabetic patients as well, as an immunity booster in the wake of the present environmental health issues.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80624695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
High blood pressure during pregnancy can signal a high-risk pregnancy and result in difficulties. The expression of Fas is critical for maintaining hypertensive immunity. Fas is prevalent in the trophoblast and enhances maternal-derived apoptosis. Because it contains acylphloroglucinol, flavonoids, tannins, and triterpenes, Rhodomyrtus tomentosa (haramonting) is commonly used in traditional Indonesian medicine to treat high blood pressure. This study aimed to investigate and determine the role of haramonting in lowering Fas expression in hypertensive rats’ placental histopathology. The rats were confirmed to be pregnant and divided into five groups: normal pregnant rats (control); hypertensive rats without treatment; and hypertensive rats given nanoherbal Rhodomyrtus tomentosa (NRT) at different doses: 100 mg/kg body weight (BW), 200 mg/kg BW, and 400 mg/kg BW. On gestation day 20, pregnant rats were euthanized under ketamine anaesthesia. Enzyme-linked immunosorbent assay (ELISA) analysis was used to examine the expression of the HSP family. Immunohistochemistry was used to assess Fas expression. In hypertensive rats, NRT lowered the systolic and diastolic blood pressure (P < 0.01), and NRT improved placental efficiency and restored birth weight. In hypertensive rats, higher doses of NRT were associated with higher levels of HSP27, HSP70, and HSP90. In placental histology, NRT suppresses Fas expression, acting as an anti-apoptotic agent in trophoblast cells. Because NRT is high in antioxidants and protects cells from hypoxia and dehydration, it suppresses Fas activity in the labyrinthine zone, basal zone, and yolk sac.
{"title":"Suppression of Fas expression in the hypertensive placental histology of rast given Nano herbal of Rhodomyrtus tomentosa leaves","authors":"P. Situmorang, R. A. Syahputra, R. H. Simanullang","doi":"10.48129/kjs.16833","DOIUrl":"https://doi.org/10.48129/kjs.16833","url":null,"abstract":"High blood pressure during pregnancy can signal a high-risk pregnancy and result in difficulties. The expression of Fas is critical for maintaining hypertensive immunity. Fas is prevalent in the trophoblast and enhances maternal-derived apoptosis. Because it contains acylphloroglucinol, flavonoids, tannins, and triterpenes, Rhodomyrtus tomentosa (haramonting) is commonly used in traditional Indonesian medicine to treat high blood pressure. This study aimed to investigate and determine the role of haramonting in lowering Fas expression in hypertensive rats’ placental histopathology. The rats were confirmed to be pregnant and divided into five groups: normal pregnant rats (control); hypertensive rats without treatment; and hypertensive rats given nanoherbal Rhodomyrtus tomentosa (NRT) at different doses: 100 mg/kg body weight (BW), 200 mg/kg BW, and 400 mg/kg BW. On gestation day 20, pregnant rats were euthanized under ketamine anaesthesia. Enzyme-linked immunosorbent assay (ELISA) analysis was used to examine the expression of the HSP family. Immunohistochemistry was used to assess Fas expression. In hypertensive rats, NRT lowered the systolic and diastolic blood pressure (P < 0.01), and NRT improved placental efficiency and restored birth weight. In hypertensive rats, higher doses of NRT were associated with higher levels of HSP27, HSP70, and HSP90. In placental histology, NRT suppresses Fas expression, acting as an anti-apoptotic agent in trophoblast cells. Because NRT is high in antioxidants and protects cells from hypoxia and dehydration, it suppresses Fas activity in the labyrinthine zone, basal zone, and yolk sac.","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87333042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Green synthesis of metal nanoparticles (NP) has emerged as a recent trend in green chemistry. However, their potential in the field of agriculture is yet underexplored. In this study, silver nanoparticles (Ag NPs) were synthesized by using the fruit juice and peel extract of Citrus maxima (Burm.) Merr. as a reducing and capping agent. The nano-primed seeds of Zea mays, Glycine max, and Cicer arietinum showed enhanced germination rate up to 90% as compared to the respective control (30-60%) and also enhanced plant growth. The HRTEM images of fruit-mediated Ag NPs showed well-dispersed particles. The XRD diffraction pattern confirmed the crystalline nature of Ag NPs with fcc lattice points of 101, 111, 200, 220, and 311 with an average crystal size of 19.1275±1.73 nm. On the other hand, the peel-mediated Ag NPs exhibited a size range of 10-20 nm with average crystal size of 19.09±1.71 nm. The FTIR spectra confirmed the presence of ʋC=C-H, ʋCH2, ʋC=O (stretch), ʋC=C (stretch), ʋC-H (bend), ʋC-O (bend) in the Ag NPs synthesized by the fruit and peel extract. The Ag NPs also showed potential antimicrobial effects against both Gram-positive (Staphylococcus aureus) and negative bacteria (Klebsiella pneumonia).
{"title":"Citrus maxima (Burm.) Merr. fruit juice and peel extract mediated synthesis of silver nanoparticles (Ag NPs) and their applications as antimicrobial agents and plant growth enhancers","authors":"Indukalpa Das, Abhijit Sonowal, B. Gogoi, Bidisha Sharma, Kaustuvmani Patowary, Debajit Borah","doi":"10.48129/kjs.19889","DOIUrl":"https://doi.org/10.48129/kjs.19889","url":null,"abstract":"Green synthesis of metal nanoparticles (NP) has emerged as a recent trend in green chemistry. However, their potential in the field of agriculture is yet underexplored. In this study, silver nanoparticles (Ag NPs) were synthesized by using the fruit juice and peel extract of Citrus maxima (Burm.) Merr. as a reducing and capping agent. The nano-primed seeds of Zea mays, Glycine max, and Cicer arietinum showed enhanced germination rate up to 90% as compared to the respective control (30-60%) and also enhanced plant growth. The HRTEM images of fruit-mediated Ag NPs showed well-dispersed particles. The XRD diffraction pattern confirmed the crystalline nature of Ag NPs with fcc lattice points of 101, 111, 200, 220, and 311 with an average crystal size of 19.1275±1.73 nm. On the other hand, the peel-mediated Ag NPs exhibited a size range of 10-20 nm with average crystal size of 19.09±1.71 nm. The FTIR spectra confirmed the presence of ʋC=C-H, ʋCH2, ʋC=O (stretch), ʋC=C (stretch), ʋC-H (bend), ʋC-O (bend) in the Ag NPs synthesized by the fruit and peel extract. The Ag NPs also showed potential antimicrobial effects against both Gram-positive (Staphylococcus aureus) and negative bacteria (Klebsiella pneumonia).","PeriodicalId":49933,"journal":{"name":"Kuwait Journal of Science & Engineering","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73039573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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