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Implementation and outcomes of a pharmacist-led social determinants of health screening and intervention program in an integrated health system specialty pharmacy model 在综合卫生系统专业药房模式中,药剂师主导的健康筛查和干预项目的社会决定因素的实施和结果。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-12-18 DOI: 10.1016/j.japh.2025.103008
Irfana Lakada, Martha Stutsky, Carolkim Huynh, Shreevidya Periyasamy, Andrea Idusuyi

Background

Social determinants of health (SDOH) are nonmedical factors that impact health outcomes. Pharmacists within integrated health system specialty pharmacies (HSSPs) are positioned to identify and address SDOH barriers.

Objective

The objective was to implement and evaluate a pharmacist-led SDOH program for HSSP patients.

Practice description

The practice innovation was implemented within 4 health systems in Michigan and Massachusetts with associated HSSPs and a standard specialty pharmacy clinical management model incorporating initial patient counseling and periodic reassessments.

Practice innovation

A SDOH screening and intervention program was developed and piloted at 4 health systems with associated HSSPs. Patients with HIV, rheumatoid arthritis (RA), and hyperlipidemia meeting pre-defined inclusion criteria were enrolled in the program from September 2023 through September 2024. After screening patients for SDOH barriers, pharmacists offered targeted interventions and structured follow-ups to ensure resolution of challenges.

Evaluation methods

Patients enrolled in the program were analyzed using data extracted from the electronic medical record and patient management platform. The primary outcome was intervention acceptance rate; secondary outcomes included intervention categories, patient-perceived value of interventions, ongoing support needs, pharmacist time spent, and clinical outcomes.

Results

Of the 50 patients (HIV: n = 6; RA: n = 27; hyperlipidemia: n = 17) enrolled, 56% completed screening and 79% of those accepted interventions. Of the 19 patients who received follow-up, 63% found the interventions beneficial, and 4 required ongoing support. The most frequent interventions included food security/nutrition (46%) and physical activity (25%). The average time per intervention was 60 min (range: 15-180 min). Patients with interventions demonstrated clinical outcomes improvements, including a mean Routine Assessment of Patient Index Data 3 score reduction of 3 points (range: 1.3-27.3) and mean low-density lipoprotein reduction of 29.8 mg/dL (range: 44-137) for RA and hyperlipidemia, respectively.

Conclusions

These pilot results suggest that a pharmacist-led SDOH program may be effective in addressing patient barriers, demonstrated by high acceptance rate and perceived benefit of interventions and improved clinical outcomes.
背景:健康的社会决定因素(SDOH)是影响健康结果的非医学因素。综合卫生系统专业药房(hsps)内的药剂师定位于识别和解决SDOH障碍。目的:目的是实施和评估药师主导的HSSP患者SDOH计划。实践描述:实践创新在密歇根州和马萨诸塞州的四个卫生系统中实施,其中包括相关的HSSPs和标准的专业药房临床管理模式,包括初始患者咨询和定期重新评估。实践创新:在具有相关HSSPs的四个卫生系统中制定并试点了SDOH筛查和干预计划。2023年9月至2024年9月,符合预定纳入标准的HIV、类风湿关节炎(RA)和高脂血症患者被纳入该项目。在筛查患者SDOH障碍后,药剂师提供有针对性的干预措施和结构化的随访,以确保挑战的解决。评估方法:采用从电子病历和患者管理平台提取的数据对入组患者进行分析。主要观察指标为干预措施接受率;次要结果包括干预类别、患者对干预的感知价值、持续支持需求、药剂师花费的时间和临床结果。结果:纳入的50例患者(HIV: n=6; RA: n=27;高脂血症:n=17)中,56%完成筛查,79%接受干预。在接受随访的19名患者中,63%认为干预措施有益,4名需要持续支持。最常见的干预措施包括粮食安全/营养(46%)和身体活动(25%)。每次干预的平均时间为60分钟(范围:15-180分钟)。干预的患者表现出临床结果的改善,包括RA和高脂血症的平均RAPID3评分分别降低3分(范围:1.3-27.3)和平均LDL降低29.75 mg/dL(范围:44-137)。结论:这些试点结果表明,药剂师主导的SDOH项目可能有效地解决了患者的障碍,表明了高接受率和干预措施的感知效益,并改善了临床结果。
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引用次数: 0
Methemoglobinemia induced by dapsone, hydroxychloroquine, and rifampin combination for post-treatment Lyme disease syndrome: A case report 氨苯砜、羟氯喹和利福平联合治疗后莱姆病综合征致高铁血红蛋白血症1例
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-12-18 DOI: 10.1016/j.japh.2025.103009
Jarett Worden, Tyler Baumeister, Sarah Stogner, Nancy Henin, Rebecca A. Stern

Background

A patient presented to the emergency department with drug-induced methemoglobinemia due to a combination of medications prescribed for post-treatment Lyme disease syndrome (PTLDS). This case highlights the potential risks of dapsone, hydroxychloroquine (HCQ), and rifampin for the management of PTLDS.

Case summary

A 62-year-old female presented to the hospital with shortness of breath and low oxygen saturation. Past medical history included a diagnosis of PTLDS, for which she was prescribed a combination of dapsone, HCQ, doxycycline, rifampin, and ivermectin at home. The patient had an oxygen saturation of 88% on room air but was otherwise clinically stable. Arterial blood gas was obtained and demonstrated an elevated methemoglobin level (11.2%). Analysis of peripheral blood smear revealed oxidative hemolysis, indicating medication-induced methemoglobinemia. Glucose-6-phosphate-dehydrogenase (G6PD) testing was ordered to assess for G6PD deficiency, as this is a known risk factor for methemoglobinemia and had not previously been evaluated for this patient. Testing did not demonstrate a G6PD deficiency for this patient. A negative Lyme total antibody test confirmed no active infection. Both dapsone and HCQ are known to induce methemoglobinemia and the addition of rifampin may enhance this effect. Patient improved on supplemental oxygen, ascorbic acid, and discontinuation of dapsone, HCQ, ivermectin, doxycycline, and rifampin therapy.

Practice implications

There is no strong evidence for any anti-infectives used for the treatment of PTLDS, with either short- or long-term use. Dapsone and HCQ can each cause methemoglobinemia. That effect may be increased when used together, especially in combination with rifampin. Appropriate risk assessment and monitoring should be considered when utilizing this combination.
目的:一位因治疗后莱姆病综合征(PTLDS)联合用药而出现药物性高铁血红蛋白血症的患者。本病例强调了氨苯砜、羟氯喹(HCQ)和利福平治疗PTLDS的潜在风险。病例总结:一名62岁女性因呼吸短促和低血氧饱和度入院。既往病史包括PTLDS的诊断,为此在家中给她开了氨苯砜、HCQ、强力霉素、利福平和伊维菌素的联合治疗。患者在室内空气中氧饱和度为88%,但其他方面临床稳定。动脉血气显示高铁血红蛋白水平升高(11.2%)。外周血涂片分析显示氧化性溶血,提示药物性高铁血红蛋白血症。葡萄糖-6-磷酸脱氢酶(G6PD)检测被要求评估G6PD缺乏症,因为G6PD是高铁血红蛋白血症的已知危险因素,以前没有对该患者进行过评估。检测未显示该患者G6PD缺乏。莱姆病总抗体试验阴性,证实无活动性感染。已知氨苯砜和HCQ都能诱导高铁血红蛋白血症,利福平的加入可能会增强这种作用。患者在补充氧气、抗坏血酸和停止氨苯砜、HCQ、伊维菌素、强力霉素和利福平治疗后病情好转。实践意义:没有强有力的证据表明任何抗感染药物用于治疗PTLDS,无论是短期还是长期使用。氨苯砜和羟氯喹均可引起高铁血红蛋白血症。当一起使用时,这种效果可能会增加,特别是与利福平合用。在使用这种组合时,应考虑适当的风险评估和监测。
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引用次数: 0
Factors that can impact community pharmacists' role in reducing health disparities 可能影响社区药剂师在减少健康差距方面的作用的因素。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-12-13 DOI: 10.1016/j.japh.2025.103007
Jenna Goins, Elizabeth Unni

Background

Social determinants of health (SDoH) significantly impact health outcomes but are often overlooked in community health care settings. Community pharmacists, as highly accessible providers, are well positioned to address these social factors and reduce health disparities. However, limited research has examined their preparedness, resource access, or current engagement in SDoH interventions.

Objective

This study assessed New York State community pharmacists' knowledge, access to, and use of SDoH-related resources using the theoretical framework proposed by Kiles et al., which examines pharmacist roles at the patient, practice, and community levels.

Methods

A cross-sectional survey of 37 items was distributed electronically to licensed community pharmacists across New York State. The survey captured data on demographics, SDoH knowledge and resource awareness, and practice-based engagement. Descriptive and inferential statistics identified key trends and associations. Two composite scores—SDoH resource awareness and availability—were generated to evaluate pharmacist familiarity with and access to social support services.

Results

A total of 355 pharmacists met eligibility criteria and completed the survey. Those with training in health disparities demonstrated significantly higher awareness of cultural practices, health screening availability, and mental health resources. While many reported availability of naloxone, immunizations, and smoking cessation services, fewer than a quarter offered disease state education, and just a fifth had training in depression screening. Fewer than one-third routinely recommended Medicare Part D enrollment. A moderately strong positive correlation was found between awareness and availability of SDoH resources. Pharmacists who spoke another language or had long-term tenure at their practice site reported greater familiarity with local needs and resources.

Conclusion

While community pharmacists in New York are positioned to address SDoH, gaps in training, mental health screening, and community engagement persist. Structured training in health disparities and mental health, along with policies to support sustainable implementation of SDoH interventions, are needed to expand pharmacists' capacity to serve vulnerable populations and advance health equity.
背景:健康的社会决定因素(SDoH)显著影响健康结果,但在社区卫生保健环境中往往被忽视。社区药剂师作为易于获得的提供者,在解决这些社会因素和减少健康差距方面处于有利地位。然而,有限的研究调查了他们的准备情况、资源获取情况或目前参与SDoH干预措施的情况。目的:本研究使用Kiles等人提出的理论框架评估了纽约州社区药剂师对sdoh相关资源的知识、获取和使用情况,该框架研究了药剂师在患者、实践和社区层面的角色。方法:以电子方式向纽约州有执照的社区药剂师分发一份包含37项内容的横断面调查。该调查收集了人口统计数据、SDoH知识和资源意识以及基于实践的参与度。描述性和推断性统计确定了主要趋势和关联。生成了两个复合分数- sdoh资源意识和可用性-来评估药剂师对社会支持服务的熟悉程度和获取情况。结果:共有355名药师符合条件并完成调查。那些接受过健康差异培训的人对文化习俗、健康筛查的可获得性和精神卫生资源的认识明显更高。虽然许多人报告了纳洛酮、免疫接种和戒烟服务的可用性,但提供疾病状态教育的不到四分之一,只有五分之一接受过抑郁症筛查方面的培训。少于三分之一的人通常建议参加医疗保险D部分。在意识和SDoH资源的可用性之间发现了中等强的正相关。会说另一种语言或在实习地点长期任职的药剂师报告说,他们更熟悉当地的需求和资源。结论:虽然纽约的社区药剂师有能力解决SDoH问题,但在培训、心理健康筛查和社区参与方面的差距仍然存在。要扩大药剂师服务弱势群体和促进卫生公平的能力,就需要对健康差距和心理健康进行有组织的培训,并制定政策支持可持续地实施卫生保健干预措施。
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引用次数: 0
Standing for science: How pharmacists can lead in an era of doubt 代表科学:药剂师如何在一个充满怀疑的时代发挥领导作用。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-12-08 DOI: 10.1016/j.japh.2025.103004
Pamela C. Heaton BSPharm, PhD, FAPhA
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引用次数: 0
Description and impact of a community pharmacy-based Collaborative Practice Agreement 基于社区药房的合作实践协议的描述和影响。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-12-08 DOI: 10.1016/j.japh.2025.102998
Levi Hill, Jacquelyn Kissel, Phil Pauvlinch, Jennifer Seifert, Rebecca Lahrman

Background

As of 2021, Ohio community pharmacists can enter into collaborative practice agreements to solve drug-related problems related to medication access, drug safety, and improve workflow for both community pharmacists and health care providers.

Objectives

The primary objective is to describe and quantify the usage of the Community Collaborative Practice Agreement (CPA) at 5 community pharmacies within an integrated clinic. The secondary objective is to evaluate the impact of the Community CPA on pharmacists and other providers at the practice.

Practice description

This study was conducted at 5 community pharmacies within a clinic throughout Ohio that provides primary care, pharmacy, dental, mental health, and social services.

Practice innovation

A community CPA covering 8 conditions under which pharmacists may prescribe medications and durable medical equipment to solve drug-related problems was implemented at 5 community pharmacies in Ohio.

Evaluation methods

A retrospective review of prescriptions written by pharmacists was conducted to assess the primary objective. A survey was created and completed by pharmacists and health care providers at the practice sites to assess the secondary objective.

Results

A total of 954 prescriptions were written by the pharmacists. The conditions most frequently written for include gender affirming care (629, 65.9%), diabetes (219, 23%), and asthma/chronic obstructive pulmonary disease (87, 9.1%). The average number of prescriptions written per month was 80 in the first year. Overall, a majority of pharmacists and providers agreed or strongly agreed that the Community CPA improved access to medications and patient safety. Workflow impact varied depending on the pharmacist or provider.

Conclusions

The Community CPA allows pharmacists to take a more active role in providing access to medications and improving patient safety while minimally impacting workflow. This type of innovative practice may help other pharmacists improve medication access and patient safety while maintaining workflow efficiency.
背景:截至2021年,俄亥俄州社区药剂师可以进入合作实践协议,以解决与药物获取、药物安全相关的药物相关问题,并改善社区药剂师和医疗保健提供者的工作流程。目标:主要目标是描述和量化社区合作实践协议(CPA)在综合诊所内5个社区药房的使用情况。第二个目标是评估社区注册会计师对药剂师和其他提供者的影响。实践描述:本研究在俄亥俄州一家诊所内的5家社区药房进行,这些诊所提供初级保健、药房、牙科、心理健康和社会服务。实践创新:在俄亥俄州的5家社区药房实施了一项社区注册会计师,该注册会计师涵盖了药剂师可以开出药物和耐用医疗设备的8种条件,以解决与药物有关的问题。方法:对药师处方进行回顾性分析,以评估主要目的。药剂师和医疗保健提供者在实践场所创建并完成了一项调查,以评估次要目标。结果:药师共开处方954张。最常写的疾病包括性别确认护理(629人,65.9%)、糖尿病(219人,23%)和哮喘/慢性阻塞性肺病(87人,9.1%)。第一年平均每月开80张处方。总体而言,大多数药剂师和提供者同意或强烈同意社区CPA改善了获得药物和患者安全的途径。工作流程的影响因药剂师或供应商而异。结论:社区注册会计师允许药剂师在提供药物获取和改善患者安全方面发挥更积极的作用,同时尽量减少对工作流程的影响。这种类型的创新实践可以帮助其他药剂师改善药物获取和患者安全,同时保持工作流程效率。
{"title":"Description and impact of a community pharmacy-based Collaborative Practice Agreement","authors":"Levi Hill,&nbsp;Jacquelyn Kissel,&nbsp;Phil Pauvlinch,&nbsp;Jennifer Seifert,&nbsp;Rebecca Lahrman","doi":"10.1016/j.japh.2025.102998","DOIUrl":"10.1016/j.japh.2025.102998","url":null,"abstract":"<div><h3>Background</h3><div>As of 2021, Ohio community pharmacists can enter into collaborative practice agreements to solve drug-related problems related to medication access, drug safety, and improve workflow for both community pharmacists and health care providers.</div></div><div><h3>Objectives</h3><div>The primary objective is to describe and quantify the usage of the Community Collaborative Practice Agreement (CPA) at 5 community pharmacies within an integrated clinic. The secondary objective is to evaluate the impact of the Community CPA on pharmacists and other providers at the practice.</div></div><div><h3>Practice description</h3><div>This study was conducted at 5 community pharmacies within a clinic throughout Ohio that provides primary care, pharmacy, dental, mental health, and social services.</div></div><div><h3>Practice innovation</h3><div>A community CPA covering 8 conditions under which pharmacists may prescribe medications and durable medical equipment to solve drug-related problems was implemented at 5 community pharmacies in Ohio.</div></div><div><h3>Evaluation methods</h3><div>A retrospective review of prescriptions written by pharmacists was conducted to assess the primary objective. A survey was created and completed by pharmacists and health care providers at the practice sites to assess the secondary objective.</div></div><div><h3>Results</h3><div>A total of 954 prescriptions were written by the pharmacists. The conditions most frequently written for include gender affirming care (629, 65.9%), diabetes (219, 23%), and asthma/chronic obstructive pulmonary disease (87, 9.1%). The average number of prescriptions written per month was 80 in the first year. Overall, a majority of pharmacists and providers agreed or strongly agreed that the Community CPA improved access to medications and patient safety. Workflow impact varied depending on the pharmacist or provider.</div></div><div><h3>Conclusions</h3><div>The Community CPA allows pharmacists to take a more active role in providing access to medications and improving patient safety while minimally impacting workflow. This type of innovative practice may help other pharmacists improve medication access and patient safety while maintaining workflow efficiency.</div></div>","PeriodicalId":50015,"journal":{"name":"Journal of the American Pharmacists Association","volume":"66 1","pages":"Article 102998"},"PeriodicalIF":2.5,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145728187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the implementation of an analgesia sedation protocol for adult mechanically ventilated patients 评估成人机械通气患者镇痛/镇静方案的实施。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-12-02 DOI: 10.1016/j.japh.2025.103003
Kristin Kaupp, Kaley McKinnon, Jenna Vardy, Sarah Koppernaes, Volker Eichhorn, Shanna Trenaman, Meghan MacKenzie

Background

Protocol-based pain and sedation protocols reduce sedative requirements, duration of mechanical ventilation, intensive care unit (ICU) length of stay (LOS), and pain intensity in critically ill adults. An analgesia sedation protocol for mechanically ventilated adults was created and implemented in 2022.

Objectives

This study aimed to assess the implementation and impact of an analgesia sedation protocol for mechanically ventilated adults on opioid and sedative medication administration, level of sedation, and duration of mechanical ventilation.

Practice description

The creation and implementation of the analgesia sedation protocol was a pharmacist-led, multidisciplinary effort. The protocol is an assessment-driven, stepwise, nurse-protocolized approach to pain and sedation management.

Practice innovation

The protocol emphasizes standardized, routine pain assessment and treatment using an analgosedation approach.

Evaluation methods

This was a single-center, retrospective, cohort study with a pre-post design.

Results

Preprotocol implementation patients received 13% more propofol (odds ratio [OR] 1.1354 [95% CI 1.1310–1.1399]) and 14% less opioid analgesic medications (OR 0.8597 [95% CI 0.8564–0.8630]) relative to the postimplementation cohort. The median Richmond Agitation Sedation Scale score was −2 in both cohorts, and the median Critical Care Pain Observation Tool was 0 in both cohorts. The median duration of mechanical ventilation decreased by 11 hours or 22% (P < 0.001), and the median ICU LOS decreased by 17 hours or 3.9% (P < 0.001) after protocol implementation.

Conclusions

This study confirms successful implementation of an analgosedation protocol through evaluation of opioid and sedative medication exposure. After the implementation, patients received 13% less propofol and 14% more opioid analgesic medications. After protocol implementation, there was a decrease in the duration of mechanical ventilation and ICU LOS.
背景:基于方案的疼痛和镇静方案减少了危重成人患者的镇静需求、机械通气时间、ICU住院时间(LOS)和疼痛强度。机械通气成人镇痛/镇静方案于2022年创建并实施。目的:评估机械通气成人镇痛/镇静方案的实施及其对阿片类药物和镇静药物给药、镇静水平和机械通气持续时间的影响。实践描述:镇痛/镇静方案的创建和实施是由药剂师领导的多学科努力。该方案是一种评估驱动的,逐步的,护士协议化的疼痛和镇静管理方法。实践创新:该方案强调标准化,常规的疼痛评估和治疗采用镇痛方法。评价方法:单中心回顾性、前后设计的队列研究。结果:与实施后队列相比,方案实施前患者使用的异丙酚增加13% (OR = 1.1354, 95% CI(1.1310, 1.1399)),阿片类镇痛药物减少14% (OR = 0.8597, 95% CI(0.8564 - 0.8630))。两个队列的中位RASS均为-2,中位CPOT均为0。方案实施后,机械通气的中位持续时间减少了11小时或22% (p值< 0.001),ICU的中位住院时间(LOS)减少了17小时或3.9% (p值< 0.001)。结论:本研究通过评估阿片类药物和镇静药物暴露证实了一种成功的镇痛镇静方案的实施。实施后患者服用的异丙酚减少13%,阿片类镇痛药物增加14%。方案实施后,机械通气持续时间和ICU LOS减少。
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引用次数: 0
Evaluating the success of a pharmacy technician training program at a large health system 评估大型卫生系统中药学技术人员培训计划的成功。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-11-19 DOI: 10.1016/j.japh.2025.103002
Sang Kit (Stephen) Wat RPH, PharmD, MPH, MS, BCPS, Patricia Roberts RPh, PharmD, MS, BCPS, BCSCP, Jacalyn Rogers RPH, PharmD, MS, BCPS, CPEL, FASHP

Background

Current literature on retention rates is limited. This study aimed to assess the University Hospitals’ (UH) Pharmacy Technician Training Program (UHPTTP) at program completion and retention rates at graduation and at 1 year after graduation.

Objective

This study aimed to measure the success of UHPTTP using retention rates.

Methods

All pharmacy technician trainees enrolled in UHPTTP at UH from November 2020 to September 2023 were included in the study. Data collection began in September 2022 and was completed by December 2023. The primary end points evaluated program completion rates, retention rates at graduation, and retention rates at 1 year. For the secondary end point, the rate of retention at 1 year of externally hired pharmacy technician was compared with the total rate of retention at 1 year of program graduates. All retention data were summarized using descriptive statistics. Categorical variables are analyzed using Fisher’s exact test.

Results

The total program completion rate of 77.8% (n = 95). The total retention rate at graduation was 93.2%. The 1-year retention rates of pharmacy technicians who were hired as graduates and external hires are 68.3% and 61.3%, respectively. The total retention rate of UHPTTP graduates was approximately 7.0% higher than external hires (P = 0.688159).

Conclusion

This study attempted to measure the success of an American Society of Health-System Pharmacists and Accreditation Council for Pharmacy Education–accredited pharmacy technician training program at a large health system. There was no statistically significant difference noted in 1-year retention rates between UHPTTP graduates and external hires. This suggests that UHPTTP was successful in producing qualified pharmacy technician candidates for internal vacant positions.
背景:目前关于保留率的文献有限。本研究旨在评估UHPTTP在项目完成时,以及毕业和毕业后1年的保留率。目的:本研究的目的是用留用率来衡量大学医院药学技术人员培训计划(UHPTTP)的成功程度。方法:纳入2020年11月至2023年9月在UH参加UHPTTP的所有药学技术实习生。数据收集始于2022年9月,并于2023年12月完成。主要终点评估项目完成率;毕业留校率;1年的保留率。对于次要终点,将外部雇用的药学技术人员1年的保留率与1年计划毕业生的总保留率进行比较。所有留存数据采用描述性统计进行汇总。分类变量采用Fisher精确检验进行分析。结果:总方案完成率77.8% (n=95)。毕业时的总保留率为93.2%。毕业聘用和外聘聘用的药学技术人员1年留任率分别为68.3%和61.3%。与外部招聘相比,UHPTTP毕业生的总保留率大约高出7.0% (p = 0.688159)。结论:本研究试图衡量ASHP/ acpe认证的大型卫生系统药房技术人员培训计划的成功。在UHPTTP毕业生和外部雇员之间的1年保留率没有统计学上的显著差异。这表明UHPTTP成功地为内部空缺职位培养了合格的药学技术人员候选人。
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引用次数: 0
Addressing pharmacy access in a landscape of pharmacy closures 解决药房关闭景观药房访问。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-11-19 DOI: 10.1016/j.japh.2025.102934
Christine Gong, Bella Blankenship, Lucas A. Berenbrok, Jennifer L. Rodis, E. Michael Murphy
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引用次数: 0
Systematic review of interest-holder perceptions of pharmacist-prescribed ulipristal acetate emergency contraception 对利益相关者对药剂师处方醋酸乌普利司妥紧急避孕的看法的系统回顾。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-11-19 DOI: 10.1016/j.japh.2025.103001
Alexis C. Delanoy, Timothy C. Hutcherson, Nicole E. Cieri-Hutcherson

Background

Emergency contraception (EC) is important for the prevention of unintended pregnancy.

Objectives

This systematic review aimed to evaluate literature assessing interest-holder perceptions of pharmacist-prescribed ulipristal acetate (UPA) EC.

Methods

A search of Embase, MEDLINE, and PubMed was conducted from inception to March 3, 2025, using the following search terms and permutations: ulipristal, ella, emergency contraception, pharmacist, and pharmacy. Eligibility criteria included the following: primary literature pertaining to pharmacist-prescribed UPA EC, studies reporting on data collected in the United States, studies related to interest-holder (pharmacist, patient, and other interest-holder) perceptions, and full reports in English. Abstract-only records were excluded. Reviewers extracted and synthesized data including study characteristics and interest-holder perceptions of pharmacist-prescribed UPA. Qualitative data were coded for themes. Risk of bias (ROB) was assessed using the Appraisal tool for Cross-Sectional Studies and the Joanna Briggs Institute Narrative Critical Appraisal tool.

Results

The search yielded 1906 records; 1298 were screened after deduplication and limited to English and humans. Seven records met the inclusion criteria: 6 California-based cross-sectional studies and 1 Indiana-based pilot study. Eleven outcomes regarding pharmacist, patient, and other interest-holder perceptions were identified; 5 reports included outcomes regarding pharmacists’ perceptions, 3 included patient perceptions, and 2 included a small amount of other interest-holder perceptions. Pharmacists in 3 of 5 reports cited barriers to pharmacist-prescribed UPA; the most common included time, reimbursement for services, and support via staffing, workflow, and management. Pharmacists in 2 of 5 reports expressed desire for additional training. Patients reported benefits of pharmacist-prescribed UPA including reduced cost, time, and improved accessibility in 1 of 2 reports. Other interest holders supported pharmacist-prescribed UPA. All 7 reports had high ROB owing to the response rate.

Conclusion

Pharmacist-prescribed UPA can enhance access to EC. Education, reimbursement, and support barriers must be addressed, in addition to legislation expansion, to enhance implementation.
背景:紧急避孕(EC)对预防意外怀孕很重要。目的:本系统综述的目的是评估评估利益持有人对药剂师处方醋酸乌普利司司(UPA) EC的看法的文献。方法:对Embase、Medline和PubMed进行检索,时间跨度从起源到2025年3月3日,使用以下检索词和排列:ulipristal;埃拉;紧急避孕;药剂师;和药店。入选标准包括:与药剂师处方UPA EC相关的主要文献;报告了在美国收集的数据;与利益持有人(药剂师、患者和其他利益持有人)的看法有关;英文报告全文。仅包含摘要的记录被排除在外。审稿人提取和综合数据,包括研究特征和利益持有人对药剂师处方UPA的看法。对主题进行定性数据编码。通过横截面研究评估工具和乔安娜布里格斯研究所叙事批判性评估工具评估偏倚风险(ROB)。结果:检索得到1,906条记录;1298项在重复数据删除后进行筛选,仅限于英国人和人类。7项记录符合纳入标准:6项基于加州的横断面研究和1项基于印第安纳州的试点研究。确定了药剂师、患者和其他利益相关者感知的11个结果。五份报告包括关于药剂师的看法的结果;三个包括病人的看法,两个包括少量其他利益持有人的看法。药剂师在五分之三的报告中提到了药剂师处方UPA的障碍;最常见的包括时间、服务报销,以及通过人员配置、工作流程和管理提供的支持。五个报告中的两个药剂师表示希望接受额外的培训。在两份报告中的一份中,患者报告了药剂师处方UPA的益处,包括降低了成本、时间和改善了可及性。其他利益持有者支持药剂师处方的UPA。由于应答率,7份报告均有较高的ROB。结论:药师处方UPA可促进EC的可及性。除了扩大立法之外,还必须解决教育、报销和支持方面的障碍,以加强实施。
{"title":"Systematic review of interest-holder perceptions of pharmacist-prescribed ulipristal acetate emergency contraception","authors":"Alexis C. Delanoy,&nbsp;Timothy C. Hutcherson,&nbsp;Nicole E. Cieri-Hutcherson","doi":"10.1016/j.japh.2025.103001","DOIUrl":"10.1016/j.japh.2025.103001","url":null,"abstract":"<div><h3>Background</h3><div>Emergency contraception (EC) is important for the prevention of unintended pregnancy.</div></div><div><h3>Objectives</h3><div>This systematic review aimed to evaluate literature assessing interest-holder perceptions of pharmacist-prescribed ulipristal acetate (UPA) EC.</div></div><div><h3>Methods</h3><div>A search of Embase, MEDLINE, and PubMed was conducted from inception to March 3, 2025, using the following search terms and permutations: ulipristal, ella, emergency contraception, pharmacist, and pharmacy. Eligibility criteria included the following: primary literature pertaining to pharmacist-prescribed UPA EC, studies reporting on data collected in the United States, studies related to interest-holder (pharmacist, patient, and other interest-holder) perceptions, and full reports in English. Abstract-only records were excluded. Reviewers extracted and synthesized data including study characteristics and interest-holder perceptions of pharmacist-prescribed UPA. Qualitative data were coded for themes. Risk of bias (ROB) was assessed using the Appraisal tool for Cross-Sectional Studies and the Joanna Briggs Institute Narrative Critical Appraisal tool.</div></div><div><h3>Results</h3><div>The search yielded 1906 records; 1298 were screened after deduplication and limited to English and humans. Seven records met the inclusion criteria: 6 California-based cross-sectional studies and 1 Indiana-based pilot study. Eleven outcomes regarding pharmacist, patient, and other interest-holder perceptions were identified; 5 reports included outcomes regarding pharmacists’ perceptions, 3 included patient perceptions, and 2 included a small amount of other interest-holder perceptions. Pharmacists in 3 of 5 reports cited barriers to pharmacist-prescribed UPA; the most common included time, reimbursement for services, and support via staffing, workflow, and management. Pharmacists in 2 of 5 reports expressed desire for additional training. Patients reported benefits of pharmacist-prescribed UPA including reduced cost, time, and improved accessibility in 1 of 2 reports. Other interest holders supported pharmacist-prescribed UPA. All 7 reports had high ROB owing to the response rate.</div></div><div><h3>Conclusion</h3><div>Pharmacist-prescribed UPA can enhance access to EC. Education, reimbursement, and support barriers must be addressed, in addition to legislation expansion, to enhance implementation.</div></div>","PeriodicalId":50015,"journal":{"name":"Journal of the American Pharmacists Association","volume":"66 1","pages":"Article 103001"},"PeriodicalIF":2.5,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145575209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation and evolution of a citizen council to support patient-oriented pharmacy practice research in Ontario, Canada 实施和演变的公民委员会,以支持病人为导向的药学实践研究在安大略省,加拿大。
IF 2.5 4区 医学 Q3 PHARMACOLOGY & PHARMACY Pub Date : 2025-11-17 DOI: 10.1016/j.japh.2025.102997
Mathew DeMarco, Elizabeth Vernon-Wilson, Mansur Mehdi, Lisa Dolovich, Nancy M. Waite, Jon Jones, Zahava R.S. Rosenberg Yunger

Background

The Ontario Pharmacy Evidence Network (OPEN) introduced the OPEN Citizens’ Council (OCC) in 2019 as a forum for citizen engagement. The OCC provides OPEN researchers with a mechanism for collecting citizens’ perspectives on research priorities, strategies, data interpretation, and methods.

Objective

This paper examines the development and learning from OCC meeting data to provide insight into how a citizen advisory forum can enhance health practice research.

Methods

OCC evaluation used mixed methods. The Public and Patient Engagement Evaluation Tool (PPEET) and participant feedback interviews were offered to both OCC members and researcher presenters following OCC meetings. Descriptive statistical analysis of quantitative data (PPEET survey) was conducted. Inductive thematic analysis was used to conceptualize themes from qualitative semi-structured interviews from both OCC members and researcher presenters.

Results

Ongoing collection and analysis of survey data guided changes to OCC delivery. These included adjusting training, modifying meeting duration and scheduling, expanding preparation and discussion by posting materials online prior to meetings. Qualitative analysis of interview data led to development of four major themes: 1) rationale for participation in OCC, 2) OCC meeting experience, 3) lessons learned about citizen engagement, and 4) research impact and ramifications of citizen engagement (CE).

Conclusion

Regular evaluation enabled council development that provided pharmacy researchers with a way to explore societal views on strategic and implementation research stages. By tapping into broad, civic knowledge, citizen engagement panels can complement other research engagement activities that include patients who have specific, lived experiences. Greater recognition of engagement types, activities, and associated value, along with resources to support collaborative initiatives, will lead to a more responsive research landscape.
背景:安大略省药房证据网络(OPEN)于2019年推出了开放公民委员会(OCC),作为公民参与的论坛。OCC为OPEN研究人员提供了一种机制,用于收集公民对研究重点、策略、数据解释和方法的观点。目的:本文考察了OCC会议数据的发展和学习,以提供关于公民咨询论坛如何加强卫生实践研究的见解。方法:采用混合方法评价OCC。公众和患者参与评估工具(pepet)和参与者反馈访谈提供给OCC成员和OCC会议后的研究人员。对定量数据进行描述性统计分析(pepet调查)。从OCC成员和研究者演讲的定性半结构化访谈中,采用归纳主题分析来概念化主题。结果:持续收集和分析调查数据指导OCC交付的变化。这些措施包括调整培训、修改会议时间和日程安排、通过在会议前在线发布材料来扩大准备和讨论。访谈数据的定性分析导致了四个主要主题的发展:1)参与OCC的理性,2)OCC会议经验,3)公民参与的经验教训,4)研究影响和行政教育的后果。结论:定期评估使委员会的发展提供了一种方法,药学研究人员探索社会对战略和实施研究阶段的看法。通过利用广泛的公民知识,公民参与小组可以补充其他研究参与活动,包括有具体生活经验的患者。对参与类型、活动和相关价值的更多认识,以及支持合作倡议的资源,将导致更积极的研究前景。
{"title":"Implementation and evolution of a citizen council to support patient-oriented pharmacy practice research in Ontario, Canada","authors":"Mathew DeMarco,&nbsp;Elizabeth Vernon-Wilson,&nbsp;Mansur Mehdi,&nbsp;Lisa Dolovich,&nbsp;Nancy M. Waite,&nbsp;Jon Jones,&nbsp;Zahava R.S. Rosenberg Yunger","doi":"10.1016/j.japh.2025.102997","DOIUrl":"10.1016/j.japh.2025.102997","url":null,"abstract":"<div><h3>Background</h3><div>The Ontario Pharmacy Evidence Network (OPEN) introduced the OPEN Citizens’ Council (OCC) in 2019 as a forum for citizen engagement. The OCC provides OPEN researchers with a mechanism for collecting citizens’ perspectives on research priorities, strategies, data interpretation, and methods.</div></div><div><h3>Objective</h3><div>This paper examines the development and learning from OCC meeting data to provide insight into how a citizen advisory forum can enhance health practice research.</div></div><div><h3>Methods</h3><div>OCC evaluation used mixed methods. The Public and Patient Engagement Evaluation Tool (PPEET) and participant feedback interviews were offered to both OCC members and researcher presenters following OCC meetings. Descriptive statistical analysis of quantitative data (PPEET survey) was conducted. Inductive thematic analysis was used to conceptualize themes from qualitative semi-structured interviews from both OCC members and researcher presenters.</div></div><div><h3>Results</h3><div>Ongoing collection and analysis of survey data guided changes to OCC delivery. These included adjusting training, modifying meeting duration and scheduling, expanding preparation and discussion by posting materials online prior to meetings. Qualitative analysis of interview data led to development of four major themes: 1) rationale for participation in OCC, 2) OCC meeting experience, 3) lessons learned about citizen engagement, and 4) research impact and ramifications of citizen engagement (CE).</div></div><div><h3>Conclusion</h3><div>Regular evaluation enabled council development that provided pharmacy researchers with a way to explore societal views on strategic and implementation research stages. By tapping into broad, civic knowledge, citizen engagement panels can complement other research engagement activities that include patients who have specific, lived experiences. Greater recognition of engagement types, activities, and associated value, along with resources to support collaborative initiatives, will lead to a more responsive research landscape.</div></div>","PeriodicalId":50015,"journal":{"name":"Journal of the American Pharmacists Association","volume":"66 1","pages":"Article 102997"},"PeriodicalIF":2.5,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145558760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of the American Pharmacists Association
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