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Laparoscopic Ultrasound-Guided Transcystic Approach for the Treatment of Common Bile Duct Stones. 腹腔镜超声引导下经胆囊入路治疗胆总管结石。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-05-10 DOI: 10.1089/lap.2024.0048
Fangze Weng, Rixin Zhang, Ling Zhu, Xinhua Wu

Background: The treatment of choledocholithiasis with nondilated common bile duct (CBD) is a challenge for surgeons who often choose endoscopic retrograde cholangiopancreatography with laparoscopic cholecystectomy (LC) staging surgery instead of simultaneous laparoscopic CBD exploration with LC because of the small CBD diameter. This study aims to introduce and assess the clinical applicability of a technique we developed to identify and extract CBD stones using laparoscopic ultrasound (LUS). Methods: We retrospectively reviewed surgical procedures and clinical data of 13 patients who underwent LC and CBD exploration using LUS between May 2022 and August 2023. The cystic duct was used for CBD stone removal. Results: Ten patients were successfully treated; 2 patients with residual stones were treated with ursodeoxycholic acid, whereas 1 patient required a microincision near the CBD and choledochoscopy because of stone incarceration in the duodenal papilla. The CBD diameter was 6 mm (5-9 mm). There were less than three CBD stones, with diameters of 2-6 mm; the median operative time was 105 minutes (range, 52-155 minutes). One patient developed postoperative cholangitis. The median postoperative hospital stay was 6 days (3-8 days). The stone clearance rate was 76.9%, and the CBD stone detection rate was 100%. No intraoperative complications, postoperative bile leakage, and mortality occurred. Conclusions: CBD exploration and transcystic stone extraction under LUS guidance are safe and effective approaches for patients with choledocholithiasis; strict control over surgical indications is necessary. This study could provide new strategies for effectively treating choledocholithiasis.

背景:由于总胆管(CBD)直径较小,外科医生通常会选择内镜逆行胰胆管造影和腹腔镜胆囊切除术(LC)分期手术,而不是同时进行腹腔镜CBD探查和LC手术。本研究旨在介绍和评估我们开发的一种利用腹腔镜超声(LUS)识别和提取 CBD 结石的技术的临床适用性。方法:我们回顾性分析了2022年5月至2023年8月期间接受LC和CBD探查的13例患者的手术过程和临床数据。CBD结石的清除使用了膀胱导管。结果:10名患者成功接受了治疗;2名残余结石患者接受了熊去氧胆酸治疗,1名患者因结石嵌顿在十二指肠乳头,需要在CBD附近做微切术并进行胆道镜检查。CBD直径为6毫米(5-9毫米)。CBD结石少于3颗,直径为2-6毫米;中位手术时间为105分钟(52-155分钟不等)。一名患者术后出现胆管炎。术后中位住院时间为6天(3-8天)。结石清除率为76.9%,CBD结石检出率为100%。无术中并发症、术后胆汁渗漏和死亡率发生。结论在LUS引导下进行CBD探查和经膀胱取石术是治疗胆总管结石患者安全有效的方法,但必须严格控制手术适应症。这项研究可为有效治疗胆总管结石提供新的策略。
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引用次数: 0
Thoracoscopic Excision of Mediastinal Bronchogenic Cysts in Children: A Case Series. 胸腔镜下儿童纵隔支气管源性囊肿切除术:病例系列。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-02-14 DOI: 10.1089/lap.2023.0385
Nicholas Schmoke, Chloe Porigow, Yeu Sanz Wu, Matthew Alexander, Alexander V Chalphin, Steven Rothenberg, Vincent Duron

Background: Bronchogenic cysts result from a congenital anomalous budding of the tracheobronchial tree. Resection is usually recommended to avoid complications. Mediastinal bronchogenic cysts present a unique challenge due to their proximity to vital structures. The purpose of this study is to review our experience with mediastinal bronchogenic cysts. Methods: A single-institution retrospective review evaluated all mediastinal bronchogenic cyst excisions between January 2012 and November 2022. Patient demographics were assessed, including age at diagnosis, presenting symptoms, imaging workup, and cyst characteristics. Operative approach, complications, and surgical pathology were reported. Results: Five patients were identified. Age at diagnosis ranged from 18 to 27 months. No patient was diagnosed prenatally. All patients had symptoms at the time of diagnosis, including cough, wheezing, and respiratory distress. Three cysts were paratracheal, and two were paraesophageal. Age at surgery ranged from 26 to 30 months. All bronchogenic cysts were successfully resected thoracoscopically. Individual technical challenges included narrowing of the mainstem bronchus preventing lung isolation, significant mediastinal inflammation, the necessity for cyst evacuation to delineate the extent of the cyst, adherence of cyst wall to bronchus or trachea requiring cold dissection, and a stalk of tissue with an intimate connection to the carina that was amputated. No intraoperative or postoperative complication occurred. Surgical pathology was consistent with a bronchogenic cyst in all cases. Median length of hospital stay was two days. Conclusion: Thoracoscopy is a safe and effective procedure for mediastinal bronchogenic cyst excision in children. Certain technical maneuvers are highlighted, which may facilitate resection.

背景:支气管源性囊肿源于气管支气管树的先天性异常发芽。为避免并发症,通常建议切除囊肿。纵隔支气管源性囊肿由于靠近重要结构,因此具有独特的挑战性。本研究旨在回顾我们在纵隔支气管源性囊肿方面的经验。方法:对 2012 年 1 月至 2022 年 11 月期间的所有纵隔支气管源性囊肿切除术进行单一机构回顾性评估。对患者的人口统计学特征进行了评估,包括确诊时的年龄、主要症状、影像学检查和囊肿特征。报告了手术方法、并发症和手术病理。结果:共发现五名患者。确诊年龄为18至27个月。没有患者在产前确诊。所有患者在确诊时都出现了咳嗽、喘息和呼吸困难等症状。三个囊肿位于气管旁,两个位于食管旁。手术时的年龄在26到30个月之间。所有支气管源性囊肿均在胸腔镜下成功切除。个别技术难题包括主干支气管狭窄导致无法分离肺部、纵隔炎症严重、必须排空囊肿以划定囊肿范围、囊壁与支气管或气管粘连需要冷剥离,以及与心尖紧密连接的组织柄被截除。术中和术后均未出现并发症。所有病例的手术病理结果都与支气管源性囊肿一致。中位住院时间为两天。结论:胸腔镜手术是一种安全有效的儿童纵隔支气管源性囊肿切除术。本文重点介绍了一些可促进切除的技术操作。
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引用次数: 0
Robotic-Assisted Management of Ureteral Complications in Post-Renal Transplant Patients: A Case Series and Literature Review. 肾移植术后患者输尿管并发症的机器人辅助治疗:病例系列和文献综述
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-05-09 DOI: 10.1089/lap.2024.0080
Michael McCabe, Ashwani Sharma, Randeep Kashyap, Karen Pineda-Solis, Amit Nair, Jean Joseph, Guan Wu

Introduction: Urologic complications are thought to be the most common surgical complication of renal transplantation. Ureteral pathology, including stenosis, urine leak, and vesicoureteral reflux, predominates. Although endourologic and interventional radiological management may be utilized, failure rates remain relatively high and surgical reconstruction remains the definitive management. Robotic ureteral reconstruction has been demonstrated to provide patient benefit in nontransplant populations, but the literature on transplant reconstruction is very limited. This study reports an additional series of patients with a focus on surgical technique, as well as reviews the available evidence for robotic reconstruction for post-transplant ureteral complications. Methods: All institutional patients undergoing robotic-assisted reconstruction for post-transplant ureteral complications for the years 2019-2022 were included. Intra- and postoperative variables, patient demographics, and follow-up data were obtained retrospectively from parsing of patient records. Statistics were tabulated descriptively. Results: Eleven patients underwent ureteral reconstruction. Of the 11, 9 (81%) were male with a mean age of 51.9 years (16-70) and BMI of 33.8 (24.3-49.1). The most common (10/11) indication for reconstruction was stricture; the most common (10/11) technique used was Lich-Gregoir reimplantation. Mean operative time was 288 minutes (143-500). There were no intra- or immediate postoperative complications. Median length of stay was 2 days (1-22). There were two incidences of mortality at 2 and 5 months postoperatively unrelated to surgery. There were four readmissions within 30 days, three for urinary tract infection (UTI) and one for a pelvic abscess which required washout. The remainder of the cohort has been followed for a mean of 14.6 months (6-41) without any incidences of graft loss or recurrence of ureteral pathology. Conclusions: Robotic-assisted ureteral reconstruction is a technically challenging but highly feasible technique that may provide the benefits of minimally invasive surgery while still allowing definitive reconstruction. Centers with extensive robotic capabilities should consider the technique.

导言:泌尿系统并发症被认为是肾移植手术最常见的并发症。输尿管病变(包括狭窄、漏尿和膀胱输尿管反流)占主导地位。虽然可以采用输尿管内科和介入放射学治疗,但失败率仍然相对较高,手术重建仍是最终的治疗方法。在非移植人群中,机器人输尿管重建术已被证明能为患者带来益处,但有关移植重建的文献却非常有限。本研究报告了一组额外的患者,重点介绍了手术技术,并回顾了机器人重建术治疗移植后输尿管并发症的现有证据。方法:纳入2019-2022年间所有接受机器人辅助重建术治疗输尿管移植术后并发症的住院患者。术中和术后变量、患者人口统计学和随访数据均通过解析患者病历回顾性获得。统计数据以表格形式描述。结果11名患者接受了输尿管重建术。在这 11 位患者中,9 位(81%)为男性,平均年龄为 51.9 岁(16-70 岁),体重指数为 33.8(24.3-49.1)。最常见(10/11)的重建适应症是狭窄;最常用(10/11)的技术是 Lich-Gregoir 再植术。平均手术时间为 288 分钟(143-500 分钟)。无术中或术后即刻并发症。中位住院时间为 2 天(1-22 天)。术后 2 个月和 5 个月分别有两例与手术无关的死亡病例。有四例患者在术后30天内再次入院,其中三例是因为尿路感染(UTI),一例是因为盆腔脓肿,需要进行冲洗。其余患者的平均随访时间为 14.6 个月(6-41 个月),没有发生移植物脱落或输尿管病变复发的情况。结论机器人辅助输尿管重建是一项具有技术挑战性但非常可行的技术,它既能提供微创手术的优势,又能进行明确的重建。具有广泛机器人能力的中心应考虑采用该技术。
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引用次数: 0
Ventral ETEP Versus REPA, Comparison of Two Novel Minimally Invasive Techniques for Midline Defects. 腹侧 ETEP 与 REPA,两种治疗中线缺损的新型微创技术的比较。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-06-20 DOI: 10.1089/lap.2024.0108
Franco Signorini, Belen Soria, Digby Montechiari, Micaela Rossi, Lucio Obeide, Alejandro Rossini

Introduction: This report aimed to compare ventral extended vision extraperitoneal (ETEP) and preaponeurotic repair (REPA) techniques in terms of surgical procedure, outcomes, and patient evolution. Methods: This was a retrospective study performed at a tertiary care academic center between 2017 and 2022. All consecutive patients operated on for midline hernias and rectus diastasis using REPA and ETEP were included. Follow-up visits were at 15 days, 30 days, and 6 months postoperative. Age, sex, BMI, American Surgical Anesthesiologic Classification (ASA), surgical time, need for conversion to open surgery, time of stay, seroma, hematoma, surgical site infection (SSI), recurrence, and re-interventions were assessed. Results: For the present study, 148 patients were included. From them, 62 patients received the REPA procedure and 86 were operated on using the ETEP technique. REPA average time was 105 minutes (interquartile range [IR] 80-130), and ETEP average time was 120 minutes (RIC 95-285) (p = 0.03). Ambulatory procedures were 32.3% (n = 20) REPA and 20.9% (n = 18) ETEP (p = 0.23). In REPA, the mean time for drain extraction was 11.92 days and 8 days in ETEP (p < 0.001). Seroma incidence was identified in 40.3% (n = 25) of the REPA cases and 5.8% (n = 5) of the ETEP procedures (p = 0.001). In a multivariate analysis for seroma incidence REPA technique was associated with a significant risk of its incidence [odds ratio (OR) 16, 67 95% confidence interval ((CI95) 4.67-59.52), p < 0.001]. Conclusion: REPA and ETEP are safe and reproducible. Both approaches reported short hospitalization times and almost no major complications. We found a longer surgical time in ETEP and a higher incidence of seroma in REPA.

导言:本报告旨在比较腹腔镜腹膜外延伸视野(ETEP)和腹膜前修复(REPA)技术在手术过程、结果和患者演变方面的优势。研究方法这是一项回顾性研究,于2017年至2022年间在一家三级医疗学术中心进行。纳入了所有使用 REPA 和 ETEP 对中线疝和直肌舒张症进行手术的连续患者。随访时间为术后 15 天、30 天和 6 个月。对年龄、性别、体重指数(BMI)、美国外科麻醉学分类(ASA)、手术时间、是否需要转为开放手术、住院时间、血清肿、血肿、手术部位感染(SSI)、复发和再次干预进行了评估。结果本研究共纳入 148 名患者。其中 62 名患者接受了 REPA 手术,86 名患者使用 ETEP 技术进行了手术。REPA 平均时间为 105 分钟(四分位数间距 [IR] 80-130),ETEP 平均时间为 120 分钟(RIC 95-285)(P = 0.03)。门诊手术中,REPA 占 32.3%(n = 20),ETEP 占 20.9%(n = 18)(p = 0.23)。在 REPA 中,拔出引流管的平均时间为 11.92 天,而在 ETEP 中为 8 天(p < 0.001)。40.3% 的 REPA 病例(n = 25)和 5.8% 的 ETEP 病例(n = 5)发现了血清肿发生率(p = 0.001)。在血清肿发生率的多变量分析中,REPA 技术与血清肿发生率的显著风险相关[几率比(OR)16.67,95% 置信区间(CI95)4.67-59.52,P <0.001]。结论REPA 和 ETEP 安全且可重复。两种方法的住院时间都很短,几乎没有重大并发症。我们发现 ETEP 的手术时间更长,而 REPA 的血清肿发生率更高。
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引用次数: 0
The Effect of Reusable Flexible Ureteroscope Aging on the Efficacy and Safety of Retrograde Intrarenal Surgery. 可重复使用的柔性输尿管镜老化对逆行肾内手术有效性和安全性的影响
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-05-08 DOI: 10.1089/lap.2024.0097
Cenk Murat Yazici, Hakan Cakir, Oktay Ozman, Cem Basatac, Haci Murat Akgul, Onder Cinar, Duygu Siddikoglu, Eyup Burak Sancak, Barbaros Baseskioglu, Anil Keles, Bulent Onal, Haluk Akpinar

Purpose: Reusable flexible ureteroscopes may lose their mechanical functionality through overuse, which is known as "aging of the flexible ureteroscope." Although mechanical deterioration has been shown in several studies, the data about the effect of this situation on the efficacy and safety of retrograde intrarenal surgery (RIRS) are missing. The aim of our study was to evaluate the effect of the aging of flexible ureteroscopes on the efficacy and safety of RIRS. Methods: Patients who had undergone RIRS between 2017 and 2021 at a single center were retrospectively included in the study. Serial surgeries were performed using the same reusable flexible ureteroscope (Storz X2) until it was broken or malfunctioned because of the aging process. Group 1 was formed by the first 10 cases on whom the flexible ureteroscopes were used, representing the youngest period of the instruments, whereas group 2 was composed of the last 10 cases on whom the flexible ureteroscopes were used, representing the oldest phase of the instruments. The operative and postoperative data-including the operation time, hospitalization time, intraoperative complications, postoperative complications, and stone-free rates-were compared between the two groups. Results: A total of five flexible ureteroscopes were included in the study. The number of cases for each flexible ureteroscope ranged between 87 and 133, with a median number of 107 cases. The demographic and clinical properties of patients in both groups were similar. The operation time, lasering time, and total laser pulse were similar between the groups. The stone-free rates in group 1 and group 2 were 82.0% and 78.0%, respectively (p = 0.304). The complication rates were also similar between the groups (p = 0.591). Conclusion: The aging of reusable flexible ureteroscopes did not negatively affect the efficacy and safety of RIRS. Therefore, surgeons may use the reusable types of flexible ureteroscopes until they are totally broken.

目的:可重复使用的柔性输尿管镜可能会因过度使用而丧失其机械功能,这就是所谓的 "柔性输尿管镜老化"。虽然已有多项研究表明输尿管软镜的机械性能会下降,但关于这种情况对逆行肾内手术(RIRS)的有效性和安全性的影响却缺乏相关数据。我们的研究旨在评估柔性输尿管镜老化对逆行肾内手术疗效和安全性的影响。研究方法研究回顾性纳入了 2017 年至 2021 年期间在一个中心接受 RIRS 的患者。使用同一可重复使用的柔性输尿管镜(Storz X2)进行连续手术,直至其因老化而破损或出现故障。第一组由使用柔性输尿管镜的前 10 个病例组成,代表该器械最年轻的阶段;第二组由使用柔性输尿管镜的最后 10 个病例组成,代表该器械最老的阶段。比较了两组的手术和术后数据,包括手术时间、住院时间、术中并发症、术后并发症和无结石率。结果本研究共纳入了五台输尿管软镜。每种输尿管软镜的病例数在 87 到 133 例之间,中位数为 107 例。两组患者的人口统计学和临床特征相似。两组的手术时间、激光时间和总激光脉冲相似。第一组和第二组的无结石率分别为 82.0% 和 78.0%(P = 0.304)。两组的并发症发生率也相似(P = 0.591)。结论可重复使用柔性输尿管镜的老化不会对 RIRS 的有效性和安全性产生负面影响。因此,外科医生可以使用可重复使用型柔性输尿管镜,直至其完全损坏。
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引用次数: 0
Experience with Laparoscopic and Robotic Colon Surgery Together with Other Major Minimally Invasive Procedures for Unrelated Pathologies. 腹腔镜和机器人结肠手术以及其他主要微创手术治疗不相关病症的经验。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-03-26 DOI: 10.1089/lap.2024.0072
Hugo J R Bonatti

Background: Indications for combined colon surgery together with other procedures include oncologic multivisceral resections and abdominal trauma. It is unclear if combining minimally invasive (MI) colon surgery with unrelated other procedures increases the risk for complications. Patients and Methods: The surgical database from two institutions during a 10-year period was queried for combined colon surgeries together with other interventions. All open cases, combined cases performed for one pathology and MI colectomies together with a minor procedure, were excluded. Results: Median age of the 6 men and 7 women was 64.4 (range 42.7-75.4) years. Colon surgeries included right (5), sigmoid (4) transverse (1) colectomies, rectum resection (1), rectopexy (1), and colostomy reversal (1) with indications of colorectal cancer (5), diverticulitis (3), benign ileocecal mass (1), colonic volvulus (3) and rectal prolapse (1). Second procedures included two splenectomies (sarcoidosis, ITP), paraesophageal hernia repairs (4), right diaphragmatic repairs [eventration (2) and Morgagni type hernia]; cholecystectomies (2), appendectomy (acute appendicitis), duodenal wedge resection (carcinoid), reversal of a gastric bypass (Roux limb stricture) one each. Cases were done laparoscopically (7) and robotic assisted (6). In most cases only 4 trocars were used. Median OR time was 4.3 (range 2.5 to 6.6) hours. No anastomotic breakdown was observed. Conclusions: Combining MI colectomy and other major abdominal surgeries can be safely done and in this series did not increase morbidity or mortality but avoids a second operation. Patient selection seems important and port placement may need to be altered to achieve good exposure for both procedures.

背景:结肠手术与其他手术合并的适应症包括肿瘤性多脏器切除和腹部创伤。目前还不清楚结肠微创手术与其他无关手术合并是否会增加并发症风险。患者和方法:对两家医疗机构 10 年间的手术数据库进行了查询,以了解结肠手术与其他干预措施的合并情况。排除了所有开放性病例、针对一种病理进行的合并病例以及MI结肠切除术合并小手术的病例。结果:6 名男性和 7 名女性的中位年龄为 64.4 岁(42.7-75.4 岁)。结肠手术包括右侧(5 例)、乙状结肠(4 例)和横结肠(1 例)切除术、直肠切除术(1 例)、直肠切除术(1 例)和结肠造口翻转术(1 例),手术适应症为结直肠癌(5 例)、憩室炎(3 例)、良性回盲部肿块(1 例)、结肠空卷(3 例)和直肠脱垂(1 例)。第二次手术包括两例脾切除术(肉样瘤病、ITP)、食道旁疝修补术(4)、右膈修补术[偶发疝(2)和莫加尼型疝];胆囊切除术(2)、阑尾切除术(急性阑尾炎)、十二指肠楔形切除术(类癌)、胃旁路逆转术(Roux肢端狭窄)各一例。病例有腹腔镜手术(7 例)和机器人辅助手术(6 例)。大多数病例只使用了 4 个套管。手术时间中位数为 4.3 小时(2.5 至 6.6 小时不等)。未观察到吻合口破裂。结论:合并 MI 结肠切除术和其他大型腹部手术是安全的,在该系列手术中,合并手术不会增加发病率或死亡率,反而避免了二次手术。患者的选择似乎很重要,可能需要改变移植口的位置,以实现两种手术的良好暴露。
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引用次数: 0
Laparoscopic-Assisted Scrotal Approach for the Treatment of Inguinal Cryptorchidism with Patent Processus Vaginalis: Clinical Efficacy Analysis. 腹腔镜辅助阴囊入路治疗腹股沟隐睾伴阴道突未闭的临床疗效分析。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2023-11-20 DOI: 10.1089/lap.2023.0361
Chengpin Tao, Yongsheng Cao, Xiang Liu, Changkun Mao

Objective: This study aimed to compare the clinical outcomes of two surgical approaches, laparoscopic-assisted scrotal incision and conventional inguinal-scrotal incision, for treating cryptorchidism with unobliterated processus vaginalis. Methods: Clinical data from 60 pediatric patients with inguinal cryptorchidism who were admitted to our institution between January 2018 and January 2022 were retrospectively analyzed. Depending on the surgical technique used, the patients were split into two groups: the laparoscopic group (n = 30) underwent a laparoscopic-assisted scrotal incision, whereas the conventional group (n = 30) underwent a conventional inguinal-scrotal incision for testicular descent and fixation. The length of the procedure, intraoperative blood loss, and the typical hospital stay following the procedure were compared between the two groups. Also assessed was the frequency of postoperative complications including wound infection and hematoma development. Results: The laparoscopic group demonstrated a notably shortened average surgical duration compared with the traditional group, and this discrepancy held statistical significance (P = .017). Moreover, the laparoscopic approach resulted in a reduced volume of intraoperative blood loss, with a statistically significant distinction (P = .002), along with a decreased average length of hospital stay after surgery, also statistically significant (P = .009). Testicular retraction, atrophy, inguinal hernias, or hydrocele were not present in any group. Although the difference between the laparoscopic and open groups was not statistically significant (P > .05), the laparoscopic group saw a reduced frequency of scrotal hematoma. The frequency of wound infection was also decreased in the laparoscopic group compared with the open group, although there was no statistically significant difference (P > .05). Conclusion: The laparoscopic-assisted scrotal incision approach for testicular descent and fixation offers precise localization of cryptorchidism, reduced surgical trauma, shorter postoperative recovery time, and results in smaller scars with minimal tissue damage. The procedure showcases enhanced overall clinical effectiveness, fewer postoperative complications, heightened safety, and superior cosmetic outcomes.

目的:比较腹腔镜下阴囊切开与常规腹股沟-阴囊切开两种手术方式治疗隐睾伴阴道突未消隐的临床效果。方法:回顾性分析我院2018年1月至2022年1月收治的60例小儿腹股沟隐睾患者的临床资料。根据所使用的手术技术,将患者分为两组:腹腔镜组(n = 30)采用腹腔镜辅助阴囊切口,而常规组(n = 30)采用常规腹股沟-阴囊切口进行睾丸下降和固定。比较两组的手术时间、术中出血量和手术后的典型住院时间。还评估了术后并发症的频率,包括伤口感染和血肿的发展。结果:腹腔镜组比传统组平均手术时间明显缩短,差异有统计学意义(P = 0.017)。此外,腹腔镜入路术中出血量减少,差异有统计学意义(P = 0.002),术后平均住院时间缩短,差异也有统计学意义(P = 0.009)。任何组均未出现睾丸缩回、萎缩、腹股沟疝或鞘膜积液。虽然腹腔镜组与开放组比较差异无统计学意义(P > 0.05),但腹腔镜组阴囊血肿发生率明显降低。与开放组相比,腹腔镜组伤口感染发生率也有所降低,但差异无统计学意义(P > 0.05)。结论:腹腔镜辅助下阴囊切口入路睾丸下降固定能精确定位隐睾,手术创伤小,术后恢复时间短,瘢痕小,组织损伤小。该手术显示了增强的整体临床效果,更少的术后并发症,更高的安全性和更好的美容效果。
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引用次数: 0
Application of Endoscopic Submucosal Dissection (ESD) in Treatment of Gastrointestinal Lesions-Single Center Experience. 内镜黏膜下剥离术(ESD)在胃肠道病变治疗中的应用--单中心经验。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-05-21 DOI: 10.1089/lap.2024.0083
Wojciech Ciesielski, Tomasz Klimczak, Adam Durczyński, Piotr Hogendorf, Janusz Strzelczyk

Background and Objectives: Endoscopic resection of gastrointestinal (GI) tract lesions, originating from Japan, is becoming more frequently used in European countries. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) ensure minimally invasive removal of benign, premalignant, and early neoplastic tumors of esophagus, stomach, and intestine in selected group of patients. Aim of this study was to determine the outcomes, radical resection rate (R0), and complication rate of ESD procedures performed in our department. Methods: The data from 100 ESD procedures of esophageal, gastric, duodenal, and colorectal lesions performed in out unit between 02.01.2020 and 30.06.2023 were collected and analyzed retrospectively. Results: A total of 42 male and 58 female patients in the median age of 64 years (range, 31-89 years) underwent ESD. Mean duration of the procedure was 66 minutes (ranging 25-185 minutes). Tumors were located in the esophagus in 8 cases (8%), stomach in 25 cases (25%), duodenum in 1 case (1%), and colon in 66 cases (66%). Radical resection was achieved in 98 cases (98%); 2 patients were qualified for surgical treatment. Average size of dissection lesions was 26 × 19 mm. The biggest one was 60 × 60 mm (sigmoid adenoma), and the smallest one was 5 × 5 mm (gastrointestinal neuroectodermal tumors). Complication occurred in 10 patients (10%)-9 perforations of the wall of intestine (9%) and 1 hemorrhage, which required endoscopic intervention (1%). Conclusions: Implementation of ESD to clinical practice gives the opportunity for minimally invasive, radical treatment of benign, premalignant, and early neoplastic lesions of gastrointestinal tract in selected group of patients. Experienced endoscopists, following current guidelines and standardized process of qualification, are crucial to minimize the risk of severe complications.

背景和目的:内窥镜胃肠道(GI)病变切除术源自日本,在欧洲国家的应用越来越广泛。内镜下粘膜切除术(EMR)和内镜下粘膜下剥离术(ESD)可确保对食管、胃和肠道的良性肿瘤、恶性肿瘤前期和早期肿瘤进行微创切除。本研究旨在确定在我科进行的ESD手术的结果、根治性切除率(R0)和并发症发生率。研究方法收集并回顾性分析 2020 年 1 月 2 日至 2023 年 6 月 30 日期间在我科进行的 100 例食管、胃、十二指肠和结直肠病变的 ESD 手术数据。结果:共有 42 名男性和 58 名女性患者接受了 ESD 治疗,中位年龄为 64 岁(31-89 岁)。手术平均持续时间为 66 分钟(25-185 分钟不等)。肿瘤位于食道的有 8 例(8%),胃的有 25 例(25%),十二指肠的有 1 例(1%),结肠的有 66 例(66%)。98例(98%)实现了根治性切除;2例患者符合手术治疗条件。解剖病灶的平均大小为 26 × 19 毫米。最大的为 60 × 60 毫米(乙状腺瘤),最小的为 5 × 5 毫米(胃肠神经外胚层瘤)。10名患者(10%)出现并发症--9例肠壁穿孔(9%),1例大出血,需要内镜介入治疗(1%)。结论:ESD在临床实践中的应用为微创根治胃肠道良性病变、癌前病变和早期肿瘤提供了机会。经验丰富的内镜医师必须遵循现行指南和标准化资格流程,这对最大限度地降低严重并发症的风险至关重要。
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引用次数: 0
Statistical Fragility in Minimally Invasive Colorectal Surgery Studies: A Review of Randomized Trials. 微创结直肠手术研究中的统计脆弱性:随机试验回顾。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-06-20 DOI: 10.1089/lap.2024.0121
Olajumoke M Megafu

Purpose: The P value has been used as a statistical tool in randomized controlled trials (RCTs) to establish significance but does not provide information on the robustness of a study when used alone. The fragility index (FI) provides a supplemental approach for demonstrating robustness in RCTs that report dichotomous outcomes. This study aims to determine the statistical fragility of RCTs that compare minimally invasive techniques with open techniques in managing benign and malignant colorectal diseases. Methods: Dichotomous outcomes of minimally invasive surgery versus open surgery in RCTs from 2000 to 2023 were assessed. The overall FI and fragility quotient (FQ) of each study were calculated. Results: Of the 1377 screened studies, 50 met the inclusion criteria. In total, 820 outcomes were recorded with 747 outcomes reported as not significant (P ≥ .05) and 73 as significant (P < .05). The overall FI for all studies including all outcomes was 5 (interquartile range [IQR] 4-7) with a FQ of 0.031 (IQR 0.014-0.062). Of the 50 RCTs, 6 (12%) reported a loss to follow-up that was greater than the overall FI of 5. Conclusions: As RCTs are judged increasingly beyond just the P value, practicing colorectal surgeons will benefit from using and interpreting the FI, FQ, and the P value of studies both in analyzing future RCTs and in determining whether or not to make a change in their clinical practice if there is an efficiently true discovery.

目的:P 值一直是随机对照试验 (RCT) 中用来确定显著性的统计工具,但单独使用时并不能提供有关研究稳健性的信息。脆性指数(FI)提供了一种补充方法,用于证明报告二分法结果的随机对照试验的稳健性。本研究旨在确定在治疗良性和恶性结直肠疾病时比较微创技术和开放技术的 RCT 的统计脆性。方法:对 2000 年至 2023 年期间 RCT 中微创手术与开放手术的二分法结果进行评估。计算每项研究的总FI和脆性商数(FQ)。结果:在筛选出的 1377 项研究中,有 50 项符合纳入标准。共记录了 820 项结果,其中 747 项结果无显著性意义(P ≥ .05),73 项结果有显著性意义(P < .05)。所有研究(包括所有结果)的总体 FI 为 5(四分位数间距 [IQR] 4-7),FQ 为 0.031(IQR 0.014-0.062)。在 50 项研究中,有 6 项(12%)报告的随访损失大于总体 FI 值 5。结论:随着对 RCT 的判断越来越不局限于 P 值,执业结直肠外科医生在分析未来的 RCT 和决定是否在临床实践中做出改变(如果有有效的真实发现)时,使用和解释研究的 FI、FQ 和 P 值将使他们受益匪浅。
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引用次数: 0
Gastrointestinal Stromal Tumors of the Stomach: Is There Any Advantage of Robotic Resections? A Systematic Review and Meta-Analysis. 胃肠道间质瘤:机器人切除术是否有优势?系统回顾与元分析》。
IF 1.1 4区 医学 Q3 SURGERY Pub Date : 2024-07-01 Epub Date: 2024-07-04 DOI: 10.1089/lap.2024.0075
Carlo Alberto Schena, Andrea-Pierre Luzzi, Vito Laterza, Belinda De Simone, Filippo Aisoni, Paschalis Gavriilidis, Fausto Catena, Federico Coccolini, Francesca Morciano, Fausto Rosa, Francesco Marchegiani, Nicola de'Angelis

Background: The role of robotic surgery for gastrointestinal stromal tumor (GIST) resection remains unclear. This systematic review and meta-analysis aimed to investigate the outcomes of robotic versus laparoscopic surgery in patients requiring surgery for gastric GISTs. Methods: MEDLINE, EMBASE, and the Cochrane databases were searched from inception to September 4, 2023. Two independent reviewers conducted a systematic review of the literature to select all types of analytic studies comparing robotic versus laparoscopic surgery for GISTs and reporting intraoperative, postoperative, and/or pathological outcomes. Results: Overall, 4 retrospective studies were selected, including a total of 264 patients, specifically 111 (42%) in the robotic and 153 (58%) in the laparoscopic group. Robotic surgery was associated with longer operating time (+42.46 min; 95% confidence interval [CI]: 9.34, 75.58; P=0.01; I2: 85%) and reduced use of mechanical staplers (odds ratio [OR]: 0.05; 95%CI: 0.02, 0.11; P<0.00001; I2: 92%;) compared with laparoscopy. Although nonsignificant, conversion to open surgery was less frequently reported for robotic surgery (2.7%) than laparoscopy (5.2%) (OR: 0.59; 95%CI: 0.17, 2.03; P=0.4; I2: 0%). No difference was found for postoperative and oncological outcomes. Conclusions: Robotic surgery for gastric GISTs provides similar intraoperative, postoperative, and pathological outcomes to laparoscopy, despite longer operative time.

背景:机器人手术在胃肠道间质瘤(GIST)切除术中的作用仍不明确。本系统综述和荟萃分析旨在研究机器人手术与腹腔镜手术对胃部 GIST 患者的治疗效果。研究方法检索了从开始到 2023 年 9 月 4 日的 MEDLINE、EMBASE 和 Cochrane 数据库。两位独立审稿人对文献进行了系统性回顾,筛选出所有类型的分析研究,比较机器人手术与腹腔镜手术治疗 GIST,并报告术中、术后和/或病理结果。结果:共选择了4项回顾性研究,包括264名患者,其中机器人手术组111人(42%),腹腔镜手术组153人(58%)。与腹腔镜手术相比,机器人手术的手术时间更长(+42.46 分钟;95% 置信区间 [CI]:9.34,75.58;P=0.01;I2:85%),机械订书机的使用也更少(几率比 [OR]:0.05;95%CI:0.02,0.11;P2:92%)。机器人手术(2.7%)与腹腔镜手术(5.2%)相比,转为开腹手术的比例较低(OR:0.59;95%CI:0.17,2.03;P=0.4;I2:0%),但无显著性差异。在术后和肿瘤结果方面没有发现差异。结论尽管手术时间较长,但机器人手术治疗胃GIST的术中、术后和病理结果与腹腔镜手术相似。
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引用次数: 0
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Journal of Laparoendoscopic & Advanced Surgical Techniques
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