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Fabrication and Characterization of Fast Dissolving Herbal Buccal Film Containing Mimosa Pudica Leaf Extract 含含羞草叶提取物的速溶草药颊黏膜的制备与表征
Pub Date : 2024-02-09 DOI: 10.47191/ijcsrr/v7-i2-23
Arpitha G, Dr. Anu Kaushik
Buccal films has distinct advantages over conventional dosage forms. Drugs can be delivered through buccal route, by avoiding first pass metabolism to produce local and systemic action. Rapid absorption of the drug is achieved because buccal mucosa is highly permeable with rich blood supply. Only few dosage forms are designed to deliver the drug through this route. Leaf extract of Mimosa pudica has number of pharmacological actions. Buccal film of leaf extract of mimosa pudica is prepared by solvent casting method and evaluated for its characteristics. Six formulations were prepared, out of which F3 formulation was found promising formulation, releases 96.13% of drug in 10 minutes.
与传统剂型相比,颊膜具有明显的优势。药物可通过颊黏膜途径给药,避免了首次代谢,从而产生局部和全身作用。由于颊粘膜具有高渗透性和丰富的血液供应,因此药物吸收迅速。能通过这种途径给药的剂型很少。含羞草叶提取物具有多种药理作用。含羞草叶提取物的颊膜是通过溶剂浇铸法制备的,并对其特性进行了评估。共制备了六种配方,其中 F3 配方在 10 分钟内释放了 96.13% 的药物,是一种很有前景的配方。
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引用次数: 0
The Peculiarities of Studies on the Stability of Ambronat 安布罗纳特稳定性研究的特殊性
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-18
Kholida Mannanovna Yunusova
In this article, the quality indicators for determining the persistence of a cough–stimulating and secretomotor type of drug commonly used in the treatment of inflammatory diseases of the upper respiratory tract were investigated. “Ambronate” qiyami did not change its color, taste and smell during the years of its stability in terms of its appearance. The indicator of рN environment is normally in the range of 5.0–7.5 and during the study it was in the range of 6.3–7.8. The results for the 3 years of the study were presented. In the 2.5–3rd year of storage, the amount of fungi and bacteria in the kiyama increased, and the results of the study in 2.5 years of storage were presented. In the quantitative analysis, the amount of ambroxol hydrochloride was determined by the spectrophotometric method, the obtained results were reflected in the regulatory documents.
本文研究了一种常用于治疗上呼吸道炎症性疾病的止咳促分泌类药物的持久性质量指标。从外观上看,"氨溴索 "qiyami 在多年的稳定性期间没有改变其颜色、味道和气味。рN环境指标通常在5.0-7.5之间,而在研究期间则在6.3-7.8之间。本报告介绍了三年的研究结果。在贮藏的第 2.5-3 年中,猕猴桃中的真菌和细菌数量有所增加,并展示了贮藏 2.5 年的研究结果。在定量分析中,采用分光光度法测定了盐酸氨溴索的含量,所得结果反映在规范性文件中。
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引用次数: 0
Human Resource Needs Planning in the Technical Implementation Unit Health Laboratory Kendari City 肯达里市卫生实验室技术实施部门的人力资源需求规划
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-21
Ida Kusumajaya, Jafriati Jafriati, Mubarak Mubarak
Introduction: Human Resource Planning Is A Structured Process Used To Predict Future Workforce Needs And Availability. Analysis Of Workforce Needs Is A Logical And Planned Step In Evaluating The Number And Competency Of Employees Required In An Organizational Unit. To Overcome The Problem Of Health Human Resource Needs, Laboratory Management Capabilities Are Needed To Accurately Plan Health Human Resource Needs In Accordance With Existing Service Requirements In Each Laboratory Unit. . Method: This Research Aims To Carry Out An Analysis Of Health Human Resource Needs Planning At The Kendari City Health Laboratory Service Technical Implementation Unit. This Type Of Research Is Qualitative Descriptive Research With A Case Study Approach. The Informants In This Study Were 6 People, 2 Informants At The Service Technical Implementation Unit Health Laboratory And 4 Informants At The Kendari City Health Service. Data Collection Was Obtained From Primary Data And Secondary Data Through In-Depth Interviews, Document Review And Literature Review. Data Analysis Techniques Include Data Reduction, Data Presentation And Drawing Conclusions. Results And Conclusions: The Research Results Show That In Planning Health Human Resources Needs There Is No Standard Operating Procedure, There Is No Policy In The Form Of A Planning Team Decree, There Is No Budget In Human Resources Planning, The Availability Of Data And Information Systems In The Form Of The Human Resources Application And The Renbut Application, And Using The Workload Analysis Method In Calculating Human Resources Needs.
导言:人力资源规划是用于预测未来劳动力需求和可用性的结构化流程。劳动力需求分析是评估一个组织单位所需的员工数量和能力的逻辑性和计划性步骤。为解决卫生人力资源需求问题,需要实验室管理能力,以便根据各实验室单位现有的服务要求,准确规划卫生人力资源需求。.研究方法本研究旨在对肯达利市卫生实验室服务技术实施单位的卫生人力资源需求规划进行分析。本研究属于定性描述研究,采用个案研究方法。本研究的知情者有 6 人,其中 2 人是卫生实验室服务技术实施部门的知情者,4 人是肯达里市卫生服务部门的知情者。通过深入访谈、文件审查和文献审查,从原始数据和二手数据中收集数据。数据分析技术包括数据还原、数据展示和得出结论。结果和结论:研究结果表明,在规划卫生人力资源需求时,没有标准的操作程序,没有以规划小组法令为形式的政策,没有人力资源规划预算,没有以人力资源应用程序和 Renbut 应用程序为形式的数据和信息系统,以及在计算人力资源需求时使用工作量分析方法。
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引用次数: 0
The Importance of Studying Spontaneous Speech in Computational Linguistics 在计算语言学中研究自然语音的重要性
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-20
Makhliyo Ulugbek kizi Saydalieva
This scientific work provides information on the importance of studying spontaneous speech in computational linguistics. Studying spontaneous speech has numerous practical implications. The ramifications of spontaneous speech analysis are extensive, ranging from improving voice assistants and speech-to-text systems to enhancing human-computer interaction. An examination of spontaneous speech in computational linguistics offers a more authentic depiction of language usage, poses difficulties for current models, and opens up fresh opportunities for enhancing the precision and adaptability of language processing systems. The integration of spontaneous speech analysis will be crucial in developing the discipline of computational linguistics as technology progresses.
本科学著作介绍了在计算语言学中研究自发语音的重要性。研究自发语音有许多实际意义。自发语音分析的影响非常广泛,从改进语音助手和语音转文字系统到增强人机交互,不一而足。在计算语言学中研究自发语音可以更真实地描述语言的使用情况,为现有模型带来困难,并为提高语言处理系统的精确性和适应性带来新的机遇。随着技术的进步,整合自发语音分析对计算语言学学科的发展至关重要。
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引用次数: 0
The Peculiarities of the Development of the Composition and Technology of the “Sedtab” Tablet Sedtab "平板电脑的构成和技术发展的特殊性
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-19
Kholida Mannanovna Yunusova
Today, neurological diseases occupy one of the leading places in terms of prevalence among all diseases. According to the World Health Organization, over the past 65 years, the number of neurological diseases in the world has increased more than 20 times and amounts to approximately 40%. Despite the relatively wide availability of means for the prevention and treatment of neurological diseases, the development and implementation of new, more effective and safe means remains relevant. In this regard, preparations from medicinal plants deserve special attention, since they are closer to the human body than synthetic drugs, easily enter into metabolic processes, practically do not cause side effects and often reduce negative consequences. The main goal of this work is to develop a new composition and technology for “Sedtab” tablets based on local plant materials, i.e. stinging nettle, lemon balm and motherwort, as well as the study of technological properties based on scientific criteria for the creation of medicinal products.
如今,神经系统疾病在所有疾病中的发病率位居前列。据世界卫生组织统计,在过去的 65 年中,全世界神经系统疾病的发病率增长了 20 多倍,约占 40%。尽管预防和治疗神经系统疾病的手段相对较多,但开发和实施更有效、更安全的新手段仍然具有现实意义。在这方面,来自药用植物的制剂值得特别关注,因为它们比合成药物更接近人体,容易进入新陈代谢过程,实际上不会产生副作用,而且往往能减少负面影响。这项工作的主要目标是以当地植物材料(即荨麻、柠檬香膏和益母草)为基础,开发 "Sedtab "片剂的新成分和技术,并根据创造药用产品的科学标准研究其技术特性。
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引用次数: 0
Analysis of Business Restructuring Strategies Based on a Strategic Due Diligence Approach at PT. Industri Telekomunikasi Indonesia (PERSERO) 基于战略尽职调查方法的 PT.印度尼西亚电信工业公司 (PERSERO)
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-17
Aulia Rachmadany Dwiningtyas, Ir. Dodie Tricahyono
In the ever-evolving market conditions and increasingly fierce competition, PT. INTI is faced with the challenge of carrying out an effective business restructuring in order to improve the company’s performance. The strategic due diligence approach is used in this study as a framework for analyzing business restructuring strategies. The research method used includes literature studies, secondary data analysis, and interviews with related parties at PT. INTI. The collected data were analyzed using qualitative approaches to obtain a comprehensive understanding of the company’s business situation. The results of this study reveal that PT. INTI requires a business restructuring which includes changes in business strategy, company organization, and operations. This study identified several suggested restructuring strategies, such as product and service diversification, developing new markets, increasing operational efficiency, and increasing collaboration with strategic partners.
在不断变化的市场环境和日益激烈的竞争中,PT.INTI 面临的挑战是进行有效的业务重组,以提高公司业绩。本研究采用战略尽职调查法作为分析业务重组战略的框架。采用的研究方法包括文献研究、二手数据分析以及与 PT.INTI 的相关人员进行访谈。收集到的数据采用定性方法进行分析,以获得对公司业务状况的全面了解。研究结果表明,PT.INTI 需要进行业务重组,包括改变业务战略、公司组织和运营。本研究确定了几项建议的重组战略,如产品和服务多样化、开发新市场、提高运营效率以及加强与战略伙伴的合作。
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引用次数: 0
The Peculiarities of Studies on the Stability of Ambronat 安布罗纳特稳定性研究的特殊性
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-18
Kholida Mannanovna Yunusova
In this article, the quality indicators for determining the persistence of a cough–stimulating and secretomotor type of drug commonly used in the treatment of inflammatory diseases of the upper respiratory tract were investigated. “Ambronate” qiyami did not change its color, taste and smell during the years of its stability in terms of its appearance. The indicator of рN environment is normally in the range of 5.0–7.5 and during the study it was in the range of 6.3–7.8. The results for the 3 years of the study were presented. In the 2.5–3rd year of storage, the amount of fungi and bacteria in the kiyama increased, and the results of the study in 2.5 years of storage were presented. In the quantitative analysis, the amount of ambroxol hydrochloride was determined by the spectrophotometric method, the obtained results were reflected in the regulatory documents.
本文研究了一种常用于治疗上呼吸道炎症性疾病的止咳促分泌类药物的持久性质量指标。从外观上看,"氨溴索 "qiyami 在多年的稳定性期间没有改变其颜色、味道和气味。рN环境指标通常在5.0-7.5之间,而在研究期间则在6.3-7.8之间。本报告介绍了三年的研究结果。在贮藏的第 2.5-3 年中,猕猴桃中的真菌和细菌数量有所增加,并展示了贮藏 2.5 年的研究结果。在定量分析中,采用分光光度法测定了盐酸氨溴索的含量,所得结果反映在规范性文件中。
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引用次数: 0
The Peculiarities of the Development of the Composition and Technology of the “Sedtab” Tablet Sedtab "平板电脑的构成和技术发展的特殊性
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-19
Kholida Mannanovna Yunusova
Today, neurological diseases occupy one of the leading places in terms of prevalence among all diseases. According to the World Health Organization, over the past 65 years, the number of neurological diseases in the world has increased more than 20 times and amounts to approximately 40%. Despite the relatively wide availability of means for the prevention and treatment of neurological diseases, the development and implementation of new, more effective and safe means remains relevant. In this regard, preparations from medicinal plants deserve special attention, since they are closer to the human body than synthetic drugs, easily enter into metabolic processes, practically do not cause side effects and often reduce negative consequences. The main goal of this work is to develop a new composition and technology for “Sedtab” tablets based on local plant materials, i.e. stinging nettle, lemon balm and motherwort, as well as the study of technological properties based on scientific criteria for the creation of medicinal products.
如今,神经系统疾病在所有疾病中的发病率位居前列。据世界卫生组织统计,在过去的 65 年中,全世界神经系统疾病的发病率增长了 20 多倍,约占 40%。尽管预防和治疗神经系统疾病的手段相对较多,但开发和实施更有效、更安全的新手段仍然具有现实意义。在这方面,来自药用植物的制剂值得特别关注,因为它们比合成药物更接近人体,容易进入新陈代谢过程,实际上不会产生副作用,而且往往能减少负面影响。这项工作的主要目标是以当地植物材料(即荨麻、柠檬香膏和益母草)为基础,开发 "Sedtab "片剂的新成分和技术,并根据创造药用产品的科学标准研究其技术特性。
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引用次数: 0
Analysis of Business Restructuring Strategies Based on a Strategic Due Diligence Approach at PT. Industri Telekomunikasi Indonesia (PERSERO) 基于战略尽职调查方法的 PT.印度尼西亚电信工业公司 (PERSERO)
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-17
Aulia Rachmadany Dwiningtyas, Ir. Dodie Tricahyono
In the ever-evolving market conditions and increasingly fierce competition, PT. INTI is faced with the challenge of carrying out an effective business restructuring in order to improve the company’s performance. The strategic due diligence approach is used in this study as a framework for analyzing business restructuring strategies. The research method used includes literature studies, secondary data analysis, and interviews with related parties at PT. INTI. The collected data were analyzed using qualitative approaches to obtain a comprehensive understanding of the company’s business situation. The results of this study reveal that PT. INTI requires a business restructuring which includes changes in business strategy, company organization, and operations. This study identified several suggested restructuring strategies, such as product and service diversification, developing new markets, increasing operational efficiency, and increasing collaboration with strategic partners.
在不断变化的市场环境和日益激烈的竞争中,PT.INTI 面临的挑战是进行有效的业务重组,以提高公司业绩。本研究采用战略尽职调查法作为分析业务重组战略的框架。采用的研究方法包括文献研究、二手数据分析以及与 PT.INTI 的相关人员进行访谈。收集到的数据采用定性方法进行分析,以获得对公司业务状况的全面了解。研究结果表明,PT.INTI 需要进行业务重组,包括改变业务战略、公司组织和运营。本研究确定了几项建议的重组战略,如产品和服务多样化、开发新市场、提高运营效率以及加强与战略伙伴的合作。
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引用次数: 0
Human Resource Needs Planning in the Technical Implementation Unit Health Laboratory Kendari City 肯达里市卫生实验室技术实施部门的人力资源需求规划
Pub Date : 2024-02-08 DOI: 10.47191/ijcsrr/v7-i2-21
Ida Kusumajaya, Jafriati Jafriati, Mubarak Mubarak
Introduction: Human Resource Planning Is A Structured Process Used To Predict Future Workforce Needs And Availability. Analysis Of Workforce Needs Is A Logical And Planned Step In Evaluating The Number And Competency Of Employees Required In An Organizational Unit. To Overcome The Problem Of Health Human Resource Needs, Laboratory Management Capabilities Are Needed To Accurately Plan Health Human Resource Needs In Accordance With Existing Service Requirements In Each Laboratory Unit. . Method: This Research Aims To Carry Out An Analysis Of Health Human Resource Needs Planning At The Kendari City Health Laboratory Service Technical Implementation Unit. This Type Of Research Is Qualitative Descriptive Research With A Case Study Approach. The Informants In This Study Were 6 People, 2 Informants At The Service Technical Implementation Unit Health Laboratory And 4 Informants At The Kendari City Health Service. Data Collection Was Obtained From Primary Data And Secondary Data Through In-Depth Interviews, Document Review And Literature Review. Data Analysis Techniques Include Data Reduction, Data Presentation And Drawing Conclusions. Results And Conclusions: The Research Results Show That In Planning Health Human Resources Needs There Is No Standard Operating Procedure, There Is No Policy In The Form Of A Planning Team Decree, There Is No Budget In Human Resources Planning, The Availability Of Data And Information Systems In The Form Of The Human Resources Application And The Renbut Application, And Using The Workload Analysis Method In Calculating Human Resources Needs.
导言:人力资源规划是用于预测未来劳动力需求和可用性的结构化流程。劳动力需求分析是评估一个组织单位所需的员工数量和能力的逻辑性和计划性步骤。为解决卫生人力资源需求问题,需要实验室管理能力,以便根据各实验室单位现有的服务要求,准确规划卫生人力资源需求。.研究方法本研究旨在对肯达利市卫生实验室服务技术实施单位的卫生人力资源需求规划进行分析。本研究属于定性描述研究,采用个案研究方法。本研究的知情者有 6 人,其中 2 人是卫生实验室服务技术实施部门的知情者,4 人是肯达里市卫生服务部门的知情者。通过深入访谈、文件审查和文献审查,从原始数据和二手数据中收集数据。数据分析技术包括数据还原、数据展示和得出结论。结果和结论:研究结果表明,在规划卫生人力资源需求时,没有标准的操作程序,没有以规划小组法令为形式的政策,没有人力资源规划预算,没有以人力资源应用程序和 Renbut 应用程序为形式的数据和信息系统,以及在计算人力资源需求时使用工作量分析方法。
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引用次数: 0
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International Journal of Current Science Research and Review
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