Pub Date : 2024-02-03DOI: 10.9734/jammr/2024/v36i15358
Timothy Hui, Hunter Greene, Paul Sasaura, Subu Subramanian, Bereket Ayalneh Sharew, Yordanos Woldebirhan, Jamin Gorman
Range of Motion (ROM) exercises are common after knee surgeries, but little has been researched about the actual amount of movement performed in active exercises at home. This was previously difficult to measure, as the patient was not in the office. But now, with wearables used during home exercises, Plethy Recupe, a digital health platform, was able to shed some light on whether full ROM is required for post-operative ROM exercises after Total Knee Arthroplasty (TKA). This study involved 170 TKA patients performed by the same orthopedic group. Demographics, such as age, gender, and BMI, office visits, and physical therapy care were all similar. For patients using Recupe, exercises were performed and average of 4.84 days per week. Recupe used a mobile app to direct exercises, and a wearable to measure the ROM. The ROM performed by these patients during home exercises ranged from 46.9 (sd 19.3) degrees in the first two weeks post-op, to 50.6 (sd 23.0) degrees at 1 month post-op. Meanwhile, the maximum ROM, as measured by the orthopedist, rose from 114 (sd 10.76) degrees before surgery, to 120 (sd 9.08) degrees at 1 month post-op. These are vastly different numbers, greater than 2 SD, and the home exercises show a great deal more variation. What is clear though is the fact that the patient did not bend their knees anywhere near the maximum range. Still, these patients experienced significantly better knee flexion recovery compared to patients at the same center who did not use Recupe, averaging 120 degrees versus 114 degrees. Also, patients using Recupe experienced significantly fewer Manipulation Under Anesthesia (MUA) complications, 2% versus 5%. As the other variables were similar for patients using Recupe and those who did not, the likely cause for these differences was frequency of home exercise performance. However, there is not a measurement of the home exercise frequency for those patients not using digital health. So, from this data, it appears that bending post-surgical knees to full range is not required for recovery. Instead, it appears that the key is exercise plan adherence, where the Recupe group performed exercises around 5 times per week.
{"title":"Post-Operative Range of Motion Exercises Performed Most Days at 50% Maximum ROM with Recupe Digital Health Improved ROM Recovery and Reduced Complications","authors":"Timothy Hui, Hunter Greene, Paul Sasaura, Subu Subramanian, Bereket Ayalneh Sharew, Yordanos Woldebirhan, Jamin Gorman","doi":"10.9734/jammr/2024/v36i15358","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15358","url":null,"abstract":"Range of Motion (ROM) exercises are common after knee surgeries, but little has been researched about the actual amount of movement performed in active exercises at home. This was previously difficult to measure, as the patient was not in the office. But now, with wearables used during home exercises, Plethy Recupe, a digital health platform, was able to shed some light on whether full ROM is required for post-operative ROM exercises after Total Knee Arthroplasty (TKA). \u0000This study involved 170 TKA patients performed by the same orthopedic group. Demographics, such as age, gender, and BMI, office visits, and physical therapy care were all similar. For patients using Recupe, exercises were performed and average of 4.84 days per week. Recupe used a mobile app to direct exercises, and a wearable to measure the ROM. The ROM performed by these patients during home exercises ranged from 46.9 (sd 19.3) degrees in the first two weeks post-op, to 50.6 (sd 23.0) degrees at 1 month post-op. Meanwhile, the maximum ROM, as measured by the orthopedist, rose from 114 (sd 10.76) degrees before surgery, to 120 (sd 9.08) degrees at 1 month post-op. \u0000These are vastly different numbers, greater than 2 SD, and the home exercises show a great deal more variation. What is clear though is the fact that the patient did not bend their knees anywhere near the maximum range. Still, these patients experienced significantly better knee flexion recovery compared to patients at the same center who did not use Recupe, averaging 120 degrees versus 114 degrees. Also, patients using Recupe experienced significantly fewer Manipulation Under Anesthesia (MUA) complications, 2% versus 5%. As the other variables were similar for patients using Recupe and those who did not, the likely cause for these differences was frequency of home exercise performance. However, there is not a measurement of the home exercise frequency for those patients not using digital health. \u0000So, from this data, it appears that bending post-surgical knees to full range is not required for recovery. Instead, it appears that the key is exercise plan adherence, where the Recupe group performed exercises around 5 times per week.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"46 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139808632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-03DOI: 10.9734/jammr/2024/v36i15358
Timothy Hui, Hunter Greene, Paul Sasaura, Subu Subramanian, Bereket Ayalneh Sharew, Yordanos Woldebirhan, Jamin Gorman
Range of Motion (ROM) exercises are common after knee surgeries, but little has been researched about the actual amount of movement performed in active exercises at home. This was previously difficult to measure, as the patient was not in the office. But now, with wearables used during home exercises, Plethy Recupe, a digital health platform, was able to shed some light on whether full ROM is required for post-operative ROM exercises after Total Knee Arthroplasty (TKA). This study involved 170 TKA patients performed by the same orthopedic group. Demographics, such as age, gender, and BMI, office visits, and physical therapy care were all similar. For patients using Recupe, exercises were performed and average of 4.84 days per week. Recupe used a mobile app to direct exercises, and a wearable to measure the ROM. The ROM performed by these patients during home exercises ranged from 46.9 (sd 19.3) degrees in the first two weeks post-op, to 50.6 (sd 23.0) degrees at 1 month post-op. Meanwhile, the maximum ROM, as measured by the orthopedist, rose from 114 (sd 10.76) degrees before surgery, to 120 (sd 9.08) degrees at 1 month post-op. These are vastly different numbers, greater than 2 SD, and the home exercises show a great deal more variation. What is clear though is the fact that the patient did not bend their knees anywhere near the maximum range. Still, these patients experienced significantly better knee flexion recovery compared to patients at the same center who did not use Recupe, averaging 120 degrees versus 114 degrees. Also, patients using Recupe experienced significantly fewer Manipulation Under Anesthesia (MUA) complications, 2% versus 5%. As the other variables were similar for patients using Recupe and those who did not, the likely cause for these differences was frequency of home exercise performance. However, there is not a measurement of the home exercise frequency for those patients not using digital health. So, from this data, it appears that bending post-surgical knees to full range is not required for recovery. Instead, it appears that the key is exercise plan adherence, where the Recupe group performed exercises around 5 times per week.
{"title":"Post-Operative Range of Motion Exercises Performed Most Days at 50% Maximum ROM with Recupe Digital Health Improved ROM Recovery and Reduced Complications","authors":"Timothy Hui, Hunter Greene, Paul Sasaura, Subu Subramanian, Bereket Ayalneh Sharew, Yordanos Woldebirhan, Jamin Gorman","doi":"10.9734/jammr/2024/v36i15358","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15358","url":null,"abstract":"Range of Motion (ROM) exercises are common after knee surgeries, but little has been researched about the actual amount of movement performed in active exercises at home. This was previously difficult to measure, as the patient was not in the office. But now, with wearables used during home exercises, Plethy Recupe, a digital health platform, was able to shed some light on whether full ROM is required for post-operative ROM exercises after Total Knee Arthroplasty (TKA). \u0000This study involved 170 TKA patients performed by the same orthopedic group. Demographics, such as age, gender, and BMI, office visits, and physical therapy care were all similar. For patients using Recupe, exercises were performed and average of 4.84 days per week. Recupe used a mobile app to direct exercises, and a wearable to measure the ROM. The ROM performed by these patients during home exercises ranged from 46.9 (sd 19.3) degrees in the first two weeks post-op, to 50.6 (sd 23.0) degrees at 1 month post-op. Meanwhile, the maximum ROM, as measured by the orthopedist, rose from 114 (sd 10.76) degrees before surgery, to 120 (sd 9.08) degrees at 1 month post-op. \u0000These are vastly different numbers, greater than 2 SD, and the home exercises show a great deal more variation. What is clear though is the fact that the patient did not bend their knees anywhere near the maximum range. Still, these patients experienced significantly better knee flexion recovery compared to patients at the same center who did not use Recupe, averaging 120 degrees versus 114 degrees. Also, patients using Recupe experienced significantly fewer Manipulation Under Anesthesia (MUA) complications, 2% versus 5%. As the other variables were similar for patients using Recupe and those who did not, the likely cause for these differences was frequency of home exercise performance. However, there is not a measurement of the home exercise frequency for those patients not using digital health. \u0000So, from this data, it appears that bending post-surgical knees to full range is not required for recovery. Instead, it appears that the key is exercise plan adherence, where the Recupe group performed exercises around 5 times per week.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"72 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139868372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.9734/jammr/2024/v36i15356
Sabrina Aparecida Wendler, Jéssica Roberta Nunes, Lais Fernanda Dranski, M. Cordeiro, R. Mainardes, Christiane Schineider Machado, A. Bini, João Alfredo Schiewe, Livia Hoyer Garcia Miranda, I. I. Kerppers
Alzheimer's disease (AD) is a neurodegenerative disorder that causes impairment in daily living activities. Although there is no consensus on the pathophysiology of this disease, neuroinflammation is known to be associated with this disease. Objective: To evaluate the anti-inflammatory effects of nanoparticles containing alpha-humulene (HUM) in an experimental model of AD. Methodology: Thirty-three animals were included in the sample, 3 of which were in the negative control group. The other 30 patients received the amyloid-beta peptide in the CA1 region of the hippocampus for neuroinflammation. The cells were allowed to rest for 30 days for the inflammatory process to occur. The HUM group was treated with α-humulene particles, the NHUM group was treated with α-humulene nanoparticles for 15 days, and the CP group was not treated. Results: There were significant differences in IFN concentrations between the CP and CN (p=0.0001), HUM and CN (p=0.0003), CP and NHUM (p=0.0006), and HUM and NHUM (p=0.0495) groups. There was no difference in TNF-α levels between the groups. IL-6 levels were significantly different between the CP and NHUM groups (p=0.0078) and between the CP and CN groups (p=0.0009). IL-12 levels were significantly different between the CP and CN (p=0.0001) and between the NHUM and CN (p=0.0160). Overall, the highest concentration was in the CP group. Concerning IL-10, there was a difference between the CP and NHUM (p=0.0003) and between the NHUM and CN (p=0.0005), with the NHUM having the highest concentration. Immunohistochemistry analysis of the anti-Tau and anti-GAPF antibodies revealed strong positivity in the CP group, positivity in the HUM group, and weak positivity in the NHUM group. Conclusion: Treatments for Alzheimer's disease and HUM and NHUM were effective.
{"title":"Anti-Inflammatory Effects of Nanoparticles Containing Alpha-Humulene in a Model of Alzheimer's Disease","authors":"Sabrina Aparecida Wendler, Jéssica Roberta Nunes, Lais Fernanda Dranski, M. Cordeiro, R. Mainardes, Christiane Schineider Machado, A. Bini, João Alfredo Schiewe, Livia Hoyer Garcia Miranda, I. I. Kerppers","doi":"10.9734/jammr/2024/v36i15356","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15356","url":null,"abstract":"Alzheimer's disease (AD) is a neurodegenerative disorder that causes impairment in daily living activities. Although there is no consensus on the pathophysiology of this disease, neuroinflammation is known to be associated with this disease. Objective: To evaluate the anti-inflammatory effects of nanoparticles containing alpha-humulene (HUM) in an experimental model of AD. Methodology: Thirty-three animals were included in the sample, 3 of which were in the negative control group. The other 30 patients received the amyloid-beta peptide in the CA1 region of the hippocampus for neuroinflammation. The cells were allowed to rest for 30 days for the inflammatory process to occur. The HUM group was treated with α-humulene particles, the NHUM group was treated with α-humulene nanoparticles for 15 days, and the CP group was not treated. Results: There were significant differences in IFN concentrations between the CP and CN (p=0.0001), HUM and CN (p=0.0003), CP and NHUM (p=0.0006), and HUM and NHUM (p=0.0495) groups. There was no difference in TNF-α levels between the groups. IL-6 levels were significantly different between the CP and NHUM groups (p=0.0078) and between the CP and CN groups (p=0.0009). IL-12 levels were significantly different between the CP and CN (p=0.0001) and between the NHUM and CN (p=0.0160). Overall, the highest concentration was in the CP group. Concerning IL-10, there was a difference between the CP and NHUM (p=0.0003) and between the NHUM and CN (p=0.0005), with the NHUM having the highest concentration. Immunohistochemistry analysis of the anti-Tau and anti-GAPF antibodies revealed strong positivity in the CP group, positivity in the HUM group, and weak positivity in the NHUM group. Conclusion: Treatments for Alzheimer's disease and HUM and NHUM were effective.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"30 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139829709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.9734/jammr/2024/v36i15354
Uangbaoje A. Cyril, Okhuoya U. Elizabeth, Okoduwa Darlington, Ajakaiye David, Abebe E. Stephen, Salami B. Goodluck, Osejele I. Meshach, Oiku A. Jeremy, A. J. Precious
Background: Malaria is one of the most important public health and life-threatening parasitic infections caused by the protozoan parasite- Plasmodium. The WHO Global technical strategy for malaria 2016–2030, updated in 2021, provides a technical framework for all malaria-endemic countries. It is intended to guide and support regional and country program as they work towards malaria control and elimination. Objectives: This study assessed the prevalence of malaria in toddlers in a tertiary health facility in developing countries between January and December 2021. Methodology: The study involved the use of patient’s case notes, A total of 104 case notes were selected using simple random technique. A checklist was generated from the collection of data. Data was analyzed using the statistical package for scientific solution (SPSS) software version 21.0. for descriptive statistics. The Chi square test was used to test for associations. The level of significance was set as P < 0.05. Results: It was discovered that Half (50%) of the toddlers were 2years old, a little above half (52.9%) were male and the mean age was 2.31 with a standard deviation of 3.02. studies. On the financial implication of malaria treatment study revealed that 76.9% spent between ₦1500 - ₦1900 and artesunate was the most common antimalarial used and most children spent up to 3 days on admission Conclusion: Findings from this study reveals that the prevalence is common among toddlers especially in 2years old. The average amount spent on antimalarial purchase is relatively fair based on the drugs the patients can afford. The highest prevalence was seen in July (62%) and the least prevalence was seen in January (30%).
{"title":"Malaria Prevalence in Toddlers: A Retrospective Study","authors":"Uangbaoje A. Cyril, Okhuoya U. Elizabeth, Okoduwa Darlington, Ajakaiye David, Abebe E. Stephen, Salami B. Goodluck, Osejele I. Meshach, Oiku A. Jeremy, A. J. Precious","doi":"10.9734/jammr/2024/v36i15354","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15354","url":null,"abstract":"Background: Malaria is one of the most important public health and life-threatening parasitic infections caused by the protozoan parasite- Plasmodium. The WHO Global technical strategy for malaria 2016–2030, updated in 2021, provides a technical framework for all malaria-endemic countries. It is intended to guide and support regional and country program as they work towards malaria control and elimination. \u0000Objectives: This study assessed the prevalence of malaria in toddlers in a tertiary health facility in developing countries between January and December 2021. \u0000Methodology: The study involved the use of patient’s case notes, A total of 104 case notes were selected using simple random technique. A checklist was generated from the collection of data. Data was analyzed using the statistical package for scientific solution (SPSS) software version 21.0. for descriptive statistics. The Chi square test was used to test for associations. The level of significance was set as P < 0.05. \u0000Results: It was discovered that Half (50%) of the toddlers were 2years old, a little above half (52.9%) were male and the mean age was 2.31 with a standard deviation of 3.02. studies. On the financial implication of malaria treatment study revealed that 76.9% spent between ₦1500 - ₦1900 and artesunate was the most common antimalarial used and most children spent up to 3 days on admission \u0000Conclusion: Findings from this study reveals that the prevalence is common among toddlers especially in 2years old. The average amount spent on antimalarial purchase is relatively fair based on the drugs the patients can afford. The highest prevalence was seen in July (62%) and the least prevalence was seen in January (30%).","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"1628 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139830797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.9734/jammr/2024/v36i15356
Sabrina Aparecida Wendler, Jéssica Roberta Nunes, Lais Fernanda Dranski, M. Cordeiro, R. Mainardes, Christiane Schineider Machado, A. Bini, João Alfredo Schiewe, Livia Hoyer Garcia Miranda, I. I. Kerppers
Alzheimer's disease (AD) is a neurodegenerative disorder that causes impairment in daily living activities. Although there is no consensus on the pathophysiology of this disease, neuroinflammation is known to be associated with this disease. Objective: To evaluate the anti-inflammatory effects of nanoparticles containing alpha-humulene (HUM) in an experimental model of AD. Methodology: Thirty-three animals were included in the sample, 3 of which were in the negative control group. The other 30 patients received the amyloid-beta peptide in the CA1 region of the hippocampus for neuroinflammation. The cells were allowed to rest for 30 days for the inflammatory process to occur. The HUM group was treated with α-humulene particles, the NHUM group was treated with α-humulene nanoparticles for 15 days, and the CP group was not treated. Results: There were significant differences in IFN concentrations between the CP and CN (p=0.0001), HUM and CN (p=0.0003), CP and NHUM (p=0.0006), and HUM and NHUM (p=0.0495) groups. There was no difference in TNF-α levels between the groups. IL-6 levels were significantly different between the CP and NHUM groups (p=0.0078) and between the CP and CN groups (p=0.0009). IL-12 levels were significantly different between the CP and CN (p=0.0001) and between the NHUM and CN (p=0.0160). Overall, the highest concentration was in the CP group. Concerning IL-10, there was a difference between the CP and NHUM (p=0.0003) and between the NHUM and CN (p=0.0005), with the NHUM having the highest concentration. Immunohistochemistry analysis of the anti-Tau and anti-GAPF antibodies revealed strong positivity in the CP group, positivity in the HUM group, and weak positivity in the NHUM group. Conclusion: Treatments for Alzheimer's disease and HUM and NHUM were effective.
{"title":"Anti-Inflammatory Effects of Nanoparticles Containing Alpha-Humulene in a Model of Alzheimer's Disease","authors":"Sabrina Aparecida Wendler, Jéssica Roberta Nunes, Lais Fernanda Dranski, M. Cordeiro, R. Mainardes, Christiane Schineider Machado, A. Bini, João Alfredo Schiewe, Livia Hoyer Garcia Miranda, I. I. Kerppers","doi":"10.9734/jammr/2024/v36i15356","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15356","url":null,"abstract":"Alzheimer's disease (AD) is a neurodegenerative disorder that causes impairment in daily living activities. Although there is no consensus on the pathophysiology of this disease, neuroinflammation is known to be associated with this disease. Objective: To evaluate the anti-inflammatory effects of nanoparticles containing alpha-humulene (HUM) in an experimental model of AD. Methodology: Thirty-three animals were included in the sample, 3 of which were in the negative control group. The other 30 patients received the amyloid-beta peptide in the CA1 region of the hippocampus for neuroinflammation. The cells were allowed to rest for 30 days for the inflammatory process to occur. The HUM group was treated with α-humulene particles, the NHUM group was treated with α-humulene nanoparticles for 15 days, and the CP group was not treated. Results: There were significant differences in IFN concentrations between the CP and CN (p=0.0001), HUM and CN (p=0.0003), CP and NHUM (p=0.0006), and HUM and NHUM (p=0.0495) groups. There was no difference in TNF-α levels between the groups. IL-6 levels were significantly different between the CP and NHUM groups (p=0.0078) and between the CP and CN groups (p=0.0009). IL-12 levels were significantly different between the CP and CN (p=0.0001) and between the NHUM and CN (p=0.0160). Overall, the highest concentration was in the CP group. Concerning IL-10, there was a difference between the CP and NHUM (p=0.0003) and between the NHUM and CN (p=0.0005), with the NHUM having the highest concentration. Immunohistochemistry analysis of the anti-Tau and anti-GAPF antibodies revealed strong positivity in the CP group, positivity in the HUM group, and weak positivity in the NHUM group. Conclusion: Treatments for Alzheimer's disease and HUM and NHUM were effective.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"44 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139889781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.9734/jammr/2024/v36i15355
M. Sivarajan, V. Rakshagan, L. Govindaraju
Dental caries has long been a frequent and costly disease in the world, with paediatric caries being the most common infectious disease. Caries risk is higher in children who live in rural areas, are impoverished, or have inadequate access to dental care. Restorative treatment should be based on the findings of an appropriate clinical examination and should ideally be part of a comprehensive treatment plan that takes into account the dentition's developmental status, caries risk assessment, the patient's oral hygiene, parental compliance and likelihood of timely recall, and the patient's willingness to cooperate for treatment. Glass–ionomers, resin ionomers, resin ionomer products, and enhanced resin-based composite systems have all been developed, and they are all having a significant impact on restoration of primary teeth.The study's goal was to evaluate pedodontists' restoration choices in youngsters in Chennai. The current study was conducted in a university dental hospital in Chennai and was a retrospective observational study. The data of Pediatrics patients from June 1, 2019 to March 31, 2021 was examined. There were 1448 patients aged 3-6 years with class 1 caries in their second mandibular teeth. The next step was to tabulate the data in Excel. The data was analysed with SPSS software, and the Chi square test was used to compare groups.
{"title":"Choice of Restorative Material by Dentists for Class I Caries in Second Mandibular Primary Molar in 3-6 Year Children Visiting a University Dental Hospital “A Retrospective Study","authors":"M. Sivarajan, V. Rakshagan, L. Govindaraju","doi":"10.9734/jammr/2024/v36i15355","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15355","url":null,"abstract":"Dental caries has long been a frequent and costly disease in the world, with paediatric caries being the most common infectious disease. Caries risk is higher in children who live in rural areas, are impoverished, or have inadequate access to dental care. Restorative treatment should be based on the findings of an appropriate clinical examination and should ideally be part of a comprehensive treatment plan that takes into account the dentition's developmental status, caries risk assessment, the patient's oral hygiene, parental compliance and likelihood of timely recall, and the patient's willingness to cooperate for treatment. Glass–ionomers, resin ionomers, resin ionomer products, and enhanced resin-based composite systems have all been developed, and they are all having a significant impact on restoration of primary teeth.The study's goal was to evaluate pedodontists' restoration choices in youngsters in Chennai. The current study was conducted in a university dental hospital in Chennai and was a retrospective observational study. The data of Pediatrics patients from June 1, 2019 to March 31, 2021 was examined. There were 1448 patients aged 3-6 years with class 1 caries in their second mandibular teeth. The next step was to tabulate the data in Excel. The data was analysed with SPSS software, and the Chi square test was used to compare groups.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"16 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139831661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.9734/jammr/2024/v36i15354
Uangbaoje A. Cyril, Okhuoya U. Elizabeth, Okoduwa Darlington, Ajakaiye David, Abebe E. Stephen, Salami B. Goodluck, Osejele I. Meshach, Oiku A. Jeremy, A. J. Precious
Background: Malaria is one of the most important public health and life-threatening parasitic infections caused by the protozoan parasite- Plasmodium. The WHO Global technical strategy for malaria 2016–2030, updated in 2021, provides a technical framework for all malaria-endemic countries. It is intended to guide and support regional and country program as they work towards malaria control and elimination. Objectives: This study assessed the prevalence of malaria in toddlers in a tertiary health facility in developing countries between January and December 2021. Methodology: The study involved the use of patient’s case notes, A total of 104 case notes were selected using simple random technique. A checklist was generated from the collection of data. Data was analyzed using the statistical package for scientific solution (SPSS) software version 21.0. for descriptive statistics. The Chi square test was used to test for associations. The level of significance was set as P < 0.05. Results: It was discovered that Half (50%) of the toddlers were 2years old, a little above half (52.9%) were male and the mean age was 2.31 with a standard deviation of 3.02. studies. On the financial implication of malaria treatment study revealed that 76.9% spent between ₦1500 - ₦1900 and artesunate was the most common antimalarial used and most children spent up to 3 days on admission Conclusion: Findings from this study reveals that the prevalence is common among toddlers especially in 2years old. The average amount spent on antimalarial purchase is relatively fair based on the drugs the patients can afford. The highest prevalence was seen in July (62%) and the least prevalence was seen in January (30%).
{"title":"Malaria Prevalence in Toddlers: A Retrospective Study","authors":"Uangbaoje A. Cyril, Okhuoya U. Elizabeth, Okoduwa Darlington, Ajakaiye David, Abebe E. Stephen, Salami B. Goodluck, Osejele I. Meshach, Oiku A. Jeremy, A. J. Precious","doi":"10.9734/jammr/2024/v36i15354","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15354","url":null,"abstract":"Background: Malaria is one of the most important public health and life-threatening parasitic infections caused by the protozoan parasite- Plasmodium. The WHO Global technical strategy for malaria 2016–2030, updated in 2021, provides a technical framework for all malaria-endemic countries. It is intended to guide and support regional and country program as they work towards malaria control and elimination. \u0000Objectives: This study assessed the prevalence of malaria in toddlers in a tertiary health facility in developing countries between January and December 2021. \u0000Methodology: The study involved the use of patient’s case notes, A total of 104 case notes were selected using simple random technique. A checklist was generated from the collection of data. Data was analyzed using the statistical package for scientific solution (SPSS) software version 21.0. for descriptive statistics. The Chi square test was used to test for associations. The level of significance was set as P < 0.05. \u0000Results: It was discovered that Half (50%) of the toddlers were 2years old, a little above half (52.9%) were male and the mean age was 2.31 with a standard deviation of 3.02. studies. On the financial implication of malaria treatment study revealed that 76.9% spent between ₦1500 - ₦1900 and artesunate was the most common antimalarial used and most children spent up to 3 days on admission \u0000Conclusion: Findings from this study reveals that the prevalence is common among toddlers especially in 2years old. The average amount spent on antimalarial purchase is relatively fair based on the drugs the patients can afford. The highest prevalence was seen in July (62%) and the least prevalence was seen in January (30%).","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139890912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.9734/jammr/2024/v36i15355
M. Sivarajan, V. Rakshagan, L. Govindaraju
Dental caries has long been a frequent and costly disease in the world, with paediatric caries being the most common infectious disease. Caries risk is higher in children who live in rural areas, are impoverished, or have inadequate access to dental care. Restorative treatment should be based on the findings of an appropriate clinical examination and should ideally be part of a comprehensive treatment plan that takes into account the dentition's developmental status, caries risk assessment, the patient's oral hygiene, parental compliance and likelihood of timely recall, and the patient's willingness to cooperate for treatment. Glass–ionomers, resin ionomers, resin ionomer products, and enhanced resin-based composite systems have all been developed, and they are all having a significant impact on restoration of primary teeth.The study's goal was to evaluate pedodontists' restoration choices in youngsters in Chennai. The current study was conducted in a university dental hospital in Chennai and was a retrospective observational study. The data of Pediatrics patients from June 1, 2019 to March 31, 2021 was examined. There were 1448 patients aged 3-6 years with class 1 caries in their second mandibular teeth. The next step was to tabulate the data in Excel. The data was analysed with SPSS software, and the Chi square test was used to compare groups.
{"title":"Choice of Restorative Material by Dentists for Class I Caries in Second Mandibular Primary Molar in 3-6 Year Children Visiting a University Dental Hospital “A Retrospective Study","authors":"M. Sivarajan, V. Rakshagan, L. Govindaraju","doi":"10.9734/jammr/2024/v36i15355","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15355","url":null,"abstract":"Dental caries has long been a frequent and costly disease in the world, with paediatric caries being the most common infectious disease. Caries risk is higher in children who live in rural areas, are impoverished, or have inadequate access to dental care. Restorative treatment should be based on the findings of an appropriate clinical examination and should ideally be part of a comprehensive treatment plan that takes into account the dentition's developmental status, caries risk assessment, the patient's oral hygiene, parental compliance and likelihood of timely recall, and the patient's willingness to cooperate for treatment. Glass–ionomers, resin ionomers, resin ionomer products, and enhanced resin-based composite systems have all been developed, and they are all having a significant impact on restoration of primary teeth.The study's goal was to evaluate pedodontists' restoration choices in youngsters in Chennai. The current study was conducted in a university dental hospital in Chennai and was a retrospective observational study. The data of Pediatrics patients from June 1, 2019 to March 31, 2021 was examined. There were 1448 patients aged 3-6 years with class 1 caries in their second mandibular teeth. The next step was to tabulate the data in Excel. The data was analysed with SPSS software, and the Chi square test was used to compare groups.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"56 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139891466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-25DOI: 10.9734/jammr/2024/v36i15349
Zainab Imtiaz, Filagot D Eshete, Laaraib Arshad, Shwetha Gopal, Muhammad Najmal Qamar Siddiqui, Tope Mwuese Anyiman, Oluwatoyin Ayo-Farai, Terwase Anyiman, Obianyo Chekwube Martin, Ome Valentina Akpughe, Henry Onyemarim, Abdeltawwab Ahmed, Kareeba Leefoon Gabriel, V. C. Ezeamii, Nicole Leonie Ho-Sang
Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have recently drawn attention as a viable therapy for acute heart failure (AHF). Despite this, a comprehensive synthesis of current research has not been undertaken. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, this systematic review evaluated eight studies involving 3,352 participants. The scope encompassed research from the last twenty years, focusing on the effectiveness of SGLT2 inhibitors in AHF management. Detailed considerations regarding the temporal context and heterogeneity were incorporated into the methodology. Results: The utilization of SGLT2 inhibitors yielded compelling results in improving cardiovascular outcomes, showcasing a substantial 58.2% reduction in major adverse cardiovascular events (MACE) and a noteworthy 15% decrease in NT-proBNP levels. Empagliflozin therapy, specifically, exhibited enhanced clinical efficacy, as indicated by a 48% improvement in the Kansas City Cardiomyopathy Questionnaire Total Symptom Score. Furthermore, a detailed analysis revealed that markers of acute kidney injury witnessed a significant reduction after the administration of empagliflozin. This reduction reached statistical significance after 3 days of treatment (P=0.02) and persisted through the 7-day assessment (P=0.003). This comprehensive exploration of the results provides a more nuanced understanding of the multifaceted benefits associated with SGLT2 inhibitors, particularly empagliflozin, in the management of acute heart failure. Conclusion: The current body of research strongly supports the application of SGLT2 inhibitors in managing AHF, emphasizing considerable improvements in clinical outcomes. Despite these positive findings, the abstract acknowledges the need for further research to determine the optimal timing, dosage, long-term safety of these inhibitors, and their effectiveness across diverse patient populations.
{"title":"Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors for Acute Heart Failure: A Systematic Review","authors":"Zainab Imtiaz, Filagot D Eshete, Laaraib Arshad, Shwetha Gopal, Muhammad Najmal Qamar Siddiqui, Tope Mwuese Anyiman, Oluwatoyin Ayo-Farai, Terwase Anyiman, Obianyo Chekwube Martin, Ome Valentina Akpughe, Henry Onyemarim, Abdeltawwab Ahmed, Kareeba Leefoon Gabriel, V. C. Ezeamii, Nicole Leonie Ho-Sang","doi":"10.9734/jammr/2024/v36i15349","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15349","url":null,"abstract":"Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have recently drawn attention as a viable therapy for acute heart failure (AHF). Despite this, a comprehensive synthesis of current research has not been undertaken. \u0000Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, this systematic review evaluated eight studies involving 3,352 participants. The scope encompassed research from the last twenty years, focusing on the effectiveness of SGLT2 inhibitors in AHF management. Detailed considerations regarding the temporal context and heterogeneity were incorporated into the methodology. \u0000Results: The utilization of SGLT2 inhibitors yielded compelling results in improving cardiovascular outcomes, showcasing a substantial 58.2% reduction in major adverse cardiovascular events (MACE) and a noteworthy 15% decrease in NT-proBNP levels. Empagliflozin therapy, specifically, exhibited enhanced clinical efficacy, as indicated by a 48% improvement in the Kansas City Cardiomyopathy Questionnaire Total Symptom Score. Furthermore, a detailed analysis revealed that markers of acute kidney injury witnessed a significant reduction after the administration of empagliflozin. This reduction reached statistical significance after 3 days of treatment (P=0.02) and persisted through the 7-day assessment (P=0.003). This comprehensive exploration of the results provides a more nuanced understanding of the multifaceted benefits associated with SGLT2 inhibitors, particularly empagliflozin, in the management of acute heart failure. \u0000Conclusion: The current body of research strongly supports the application of SGLT2 inhibitors in managing AHF, emphasizing considerable improvements in clinical outcomes. Despite these positive findings, the abstract acknowledges the need for further research to determine the optimal timing, dosage, long-term safety of these inhibitors, and their effectiveness across diverse patient populations.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"22 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139595691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-13DOI: 10.9734/jammr/2024/v36i15348
Jae Hyung Ryu, Yu Jin Kim, Sang Sik Choi
A 73-year-old woman with secondary adrenal insufficiency, who discontinued denosumab injection 9 months ago, presented with severe back pain. She was already diagnosed with an acute L1 compression fracture refractory to a month-long conservative treatment. Consequently, L1 percutaneous vertebroplasty (PVP) was performed, but the patient continued to complain of persistent lower back pain. Subsequent magnetic resonance imaging (MRI) revealed acute compression fractures at L2 and L5 vertebral body. After additional PVPs at L2 and L5, the patient experienced a dramatic reduction in pain. However, three weeks later, a new compression fracture occurred at L3, and she is currently undergoing conservative treatment. Percutaneous vertebral augmentation (PVA) is a safe and immediately effective treatment for glucocorticoid-induced osteoporosis (GIOP)-related osteoporotic vertebral compression fracture (OVCF) when pain is not controlled by conservative treatment. Abrupt discontinuation of prolonged Denosumab treatment can lead to rebound fractures; therefore, transitioning appropriately according to guidelines is recommended.
{"title":"The Effect of Percutaneous Vertebroplasty in Glucocorticoid Induced Osteoporotic Vertebral Compression Fractures: A Case Report","authors":"Jae Hyung Ryu, Yu Jin Kim, Sang Sik Choi","doi":"10.9734/jammr/2024/v36i15348","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i15348","url":null,"abstract":"A 73-year-old woman with secondary adrenal insufficiency, who discontinued denosumab injection 9 months ago, presented with severe back pain. She was already diagnosed with an acute L1 compression fracture refractory to a month-long conservative treatment. Consequently, L1 percutaneous vertebroplasty (PVP) was performed, but the patient continued to complain of persistent lower back pain. Subsequent magnetic resonance imaging (MRI) revealed acute compression fractures at L2 and L5 vertebral body. After additional PVPs at L2 and L5, the patient experienced a dramatic reduction in pain. However, three weeks later, a new compression fracture occurred at L3, and she is currently undergoing conservative treatment. Percutaneous vertebral augmentation (PVA) is a safe and immediately effective treatment for glucocorticoid-induced osteoporosis (GIOP)-related osteoporotic vertebral compression fracture (OVCF) when pain is not controlled by conservative treatment. Abrupt discontinuation of prolonged Denosumab treatment can lead to rebound fractures; therefore, transitioning appropriately according to guidelines is recommended.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139623458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：