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Assessing the Prevalence of Post-Traumatic Stress Disorder and Its Risk Factors among Adult Internally Displaced Persons in Sudan 评估苏丹成年境内流离失所者中创伤后应激障碍的患病率及其风险因素
Pub Date : 2024-07-09 DOI: 10.9734/jammr/2024/v36i75508
Sayed Halaly, A. Auf, Mohammad Almontaser Ahmed Mohammed, Adam Alnour Mouhammed, Rawia Alsayed Albasheer, Wafaa Alsadig Abd Alrahman, A. Osman
Background: Since the middle of April 2023, Sudan has experienced a large armed conflict, which resulted in millions of its people leaving their homes, being internally displaced persons (IDPs) inside the country and externally displaced to neighboring countries. A lot of them were exposed to different kinds of trauma, violence, and injuries, making them more vulnerable to psychological disorders, particularly post-traumatic stress disorder (PTSD). This study aimed to estimate the prevalence of PTSD and determine the associated risk factors among IDPs in Abo Hamad Town, Nahr Neel State, Sudan in December 2023. To our knowledge, few studies explored PTSD among IDPs in Sudan. Materials and Methods: This is a cross-sectional community-based household study in Abo Hamad Town, Nahr Neel State, Sudan. A total of 118 adult IDPs were interviewed. A pre-tested and structured questionnaire assessed the participants' socio-demographic, clinical, and psychosocial characteristics and substance and displacement–related factors. The Short Post-traumatic Stress Disorder Rating Interview (SPRINT) scale was used to examine PTSD among them. Data were collected during two weeks by a well-trained team supervised by a consultant psychiatrist. Data were analysed using the SPSS version 22. Descriptive results were displayed using frequency tables. Bivariate and multivariate logistic regression was used to identify the association between the outcome and independent variables. A p-value equal or less than 0.05 was considered statistically significant at 95% CI. Results: The study comprised 118 participants, 72.9% female and 27.1% male. The mean age was 29.94 years (SD+11.84). Most were educated; 57.6% were university graduates, and 22% had secondary education. Married individuals accounted for 46.6% of the sample, while 45.0% were single. More than half (53.4%) of the participants were unemployed. Over two-thirds (67.8%) had been displaced for over four months. A lack of social support was reported by half (50.9%) of the participants. While 16.9% had a chronic medical condition, 5.1% were identified as having a mental illness. The prevalence of PTSD among Internally displaced persons was found to be 70.3%, and a quarter (27.1%) had severe symptoms. The most frequent event was the participant located in an area prone to shooting, which was reported by 90.7% of respondents, followed by property destruction, difficulty lodging, forced detachment from family, and abnormal death of a family member or friend, reported by 53.4%, 50.8%, 37.3%, and 34.7% respectively. Experiencing multiple events was common, and more than half (52.5%) of the participants experienced four or more traumatic events. Related factors with significant association with PTSD were female gender, torture, witnessing the murder of a stranger, and multiple traumatic events experienced by the respondent. Conclusion: This study showed an alarming high prevalence of PTSD among IDPs in an urban setting. Facto
背景:自 2023 年 4 月中旬以来,苏丹经历了一场大规模武装冲突,导致数百万人背井离乡,成为国内流离失所者 (IDP),并流落到邻国。他们中的许多人遭受了各种创伤、暴力和伤害,因此更容易患上心理疾病,尤其是创伤后应激障碍(PTSD)。本研究旨在估算 2023 年 12 月苏丹奈尔州阿博哈马德镇境内流离失所者中创伤后应激障碍的患病率,并确定相关风险因素。据我们所知,很少有研究探讨苏丹境内流离失所者中的创伤后应激障碍。材料和方法:这是在苏丹奈尔河州阿博哈马德镇进行的一项以社区为基础的家庭横断面研究。共采访了 118 名成年国内流离失所者。事先经过测试的结构化问卷评估了参与者的社会人口、临床和社会心理特征以及与物质和流离失所有关的因素。创伤后应激障碍简易评定访谈(SPRINT)量表用于检查他们是否患有创伤后应激障碍。数据收集工作由一个训练有素的小组在一名精神科顾问的监督下进行,为期两周。数据使用 SPSS 22 版本进行分析。使用频率表显示描述性结果。双变量和多变量逻辑回归用于确定结果与独立变量之间的关联。在 95% CI 下,P 值等于或小于 0.05 即为具有统计学意义。研究结果本研究共有 118 名参与者,其中女性占 72.9%,男性占 27.1%。平均年龄为 29.94 岁(SD+11.84)。大多数人受过教育;57.6%为大学毕业生,22%受过中等教育。已婚者占样本的 46.6%,单身者占 45.0%。一半以上(53.4%)的参与者失业。超过三分之二(67.8%)的人流离失所已超过四个月。半数参与者(50.9%)表示缺乏社会支持。16.9%的人患有慢性疾病,5.1%的人被确认患有精神疾病。研究发现,创伤后应激障碍在境内流离失所者中的发病率为 70.3%,四分之一(27.1%)的人症状严重。90.7%的受访者报告说,最常见的事件是受访者所在地区容易发生枪击事件,其次是财产被毁、住宿困难、被迫与家人分离、家人或朋友非正常死亡,分别占 53.4%、50.8%、37.3% 和 34.7%。经历多个事件是常见现象,一半以上(52.5%)的参与者经历过四个或更多的创伤事件。与创伤后应激障碍密切相关的因素包括女性性别、酷刑、目睹陌生人被谋杀以及受访者经历过多次创伤事件。结论这项研究表明,在城市环境中的国内流离失所者中,创伤后应激障碍的发病率之高令人震惊。研究发现,与创伤后应激障碍密切相关的因素包括女性、遭受酷刑、目睹陌生人被杀以及经历过多种创伤事件。需要进一步研究国内流离失所者的创伤后应激障碍,心理支持服务对于控制创伤后应激障碍和减少国内流离失所者的痛苦至关重要。
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引用次数: 0
A Comprehensive Analysis of Outcome of Colectomy in Colorectal Cancer Patients: An Insight from Private Center from the North of Brazil 结直肠癌患者结肠切除术结果的综合分析:来自巴西北部私立中心的启示
Pub Date : 2024-07-09 DOI: 10.9734/jammr/2024/v36i75507
Charles Cruz e Silva, Weany Jeniffer Costa da Conceição, Paulo Victor Ataliba Morais, Suellen Emilliany Feitosa Machado, Raissa Norat Vanetta
Aims: to analyze results of partial or total colectomies conducted in colorectal cancer (CRC) patients at a private hospital in Belém, Pará, Brazil. Study Design: The study was cross-sectional, retrospective and descriptive. Place and duration of the study: the study analyzed medical records of CRC patients subjected to either partial or total colectomy at a hospital in Belém between 2018 and 2022. Methods: The research abided by ethical norms including the Norms for Research Involving Humans of the Health National Center. The target population was composed of CRC patients of both sexes. The definitive International Classification Diseases (ICD) C18 and C19 and the following keywords “colorectal cancer”, “colon cancer”, “partial colectomy” and “total colectomy” were used to search the medical records. The analyzed variables were: epidemiologic factors, pre-operative variables, peri-operative and post-operative variables, bleeding, oncological factors, presence of compromised lymph nodes, and early and late complications. Results: After searching the hospital records, it was found that 414 patients were hospitalized with CRC between 2018 and 2022. Of these, 288 were not considered for the study due to the exclusion criteria and, therefore, 122 patients were included in the research. Fistulas were the most common early complication and recurrence the most common late complication with significant association to the presence of positive lymph nodes to pathological staging (p=0.025). Early deaths were most recurrent in stage IV (p=0.003). No statistical relevance was found between the type of colectomy and the presence of early (p=0.906) and late (p=0.237) complications. As for surgeries, conventional surgeries were related to higher rates of complications and prolonged admission. Conclusion: Negative outcomes for CRC patients are related to pathological staging and patients with positive lymph nodes presented the worst results. In addition, robotic surgery and laparoscopy were related to faster recovery and lessened early complications.
目的:分析巴西帕拉州贝伦一家私立医院对结直肠癌(CRC)患者进行部分或全部结肠切除术的结果。研究设计:研究为横断面、回顾性和描述性。研究地点和持续时间:研究分析了2018年至2022年期间在贝伦一家医院接受部分或全部结肠切除术的CRC患者的医疗记录。研究方法:研究遵守伦理规范,包括《国家卫生中心人类研究规范》。目标人群由男性和女性 CRC 患者组成。研究人员使用明确的国际疾病分类(ICD)C18 和 C19 以及以下关键词 "结肠直肠癌"、"结肠癌"、"部分结肠切除术 "和 "全结肠切除术 "搜索病历。分析的变量包括:流行病学因素、术前变量、围手术期和术后变量、出血、肿瘤学因素、是否存在受损淋巴结以及早期和晚期并发症。研究结果经过检索医院病历,发现在2018年至2022年期间,有414名患者因CRC住院治疗。其中,288 名患者因排除标准未被考虑纳入研究,因此,122 名患者被纳入研究。瘘管是最常见的早期并发症,复发是最常见的晚期并发症,淋巴结阳性的出现与病理分期有显著关联(P=0.025)。早期死亡以 IV 期复发率最高(P=0.003)。结肠切除术的类型与早期并发症(p=0.906)和晚期并发症(p=0.237)之间没有统计学相关性。至于手术,传统手术的并发症发生率更高,住院时间更长。结论CRC患者的不良预后与病理分期有关,淋巴结阳性的患者预后最差。此外,机器人手术和腹腔镜手术恢复更快,早期并发症更少。
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引用次数: 0
Evaluating the Role of C-reactive Protein in Reducing the Rate of Negative Appendicectomies 评估 C 反应蛋白在降低阑尾切除术失败率中的作用
Pub Date : 2024-07-05 DOI: 10.9734/jammr/2024/v36i75503
Clement Odion, J. Kpolugbo, Andrew E. Dongo, F. Ogbetere
Background: Acute appendicitis is a common surgical condition of the abdomen. However, diagnostic difficulties may arise, resulting in high rate of negative appendicectomies. This study aimed to assess the role of C-reactive protein (CRP) in improving the                                  accuracy of diagnosis of acute appendicitis and thus reducing the rate of negative appendicectomies. Materials and Method: The study was a cross-sectional, hospital-based study carried out on 66 patients who had appendicectomy following a clinical diagnosis of acute appendicitis. Samples for CRP were collected from all recruited patients preoperatively.  Following appendicectomy, the appendix was sent for histology. A proforma was used to collect data. All the statistical analyses were performed using IBM statistics package for social sciences (SPSS) version 21. At 95% confidence level, p-values less than 0.05 were considered significant. Results: Thirteen (13) of the appendices removed had normal histopathologic examination, giving a negative appendicectomy rate of 19.7%. The diagnostic accuracy, sensitivity, specificity and positive predictive value for preoperative CRP were 80%, 79%, 85% and 95% respectively. Conclusion: An elevated level of  CRP is a useful aid for the diagnosis of acute appendicitis. Deferring surgery in patients with normal CRP would likely decrease the incidence of negative appendicectomies.
背景:急性阑尾炎是腹部常见的外科疾病:急性阑尾炎是腹部常见的外科疾病。然而,由于诊断困难,阑尾切除术的阴性率很高。本研究旨在评估 C 反应蛋白(CRP)在提高急性阑尾炎诊断准确性方面的作用,从而降低阑尾切除术的阴性率。材料和方法:该研究是一项以医院为基础的横断面研究,针对 66 名临床诊断为急性阑尾炎后进行阑尾切除术的患者。所有入选患者在术前都采集了 CRP 样本。 阑尾切除术后,阑尾被送去做组织学检查。数据收集采用表格形式。所有统计分析均使用 IBM 社会科学统计软件包(SPSS)第 21 版进行。在 95% 的置信水平下,P 值小于 0.05 即为显著。结果切除的阑尾中有 13 个组织病理学检查结果正常,阑尾切除阴性率为 19.7%。术前 CRP 的诊断准确性、敏感性、特异性和阳性预测值分别为 80%、79%、85% 和 95%。结论CRP 升高是诊断急性阑尾炎的有效辅助指标。对 CRP 正常的患者推迟手术可能会降低阑尾切除术阴性的发生率。
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引用次数: 0
Musculoskeletal Structures in Injuries, Recovery and Applicable Treatments: A Literature Review 受伤、恢复和适用治疗中的肌肉骨骼结构:文献综述
Pub Date : 2024-07-05 DOI: 10.9734/jammr/2024/v36i75504
Gabriela dos Santos Lopes, Ana Maria Cardoso de Freitas, Adaelson Machado Fonseca, Edwan Farias e Silva, Maria das Graças de Jesus Souza Queiroz, Paulo André Miranda Rodrigues, Rayane Lobato dos Santos, Reinaldo Miranda Barros, Vitor Hugo Auzier Lima
This article sought to provide a comprehensive and integrated view of the process of musculoskeletal injury and its rehabilitation, highlighting the importance of understanding the different tissues involved, biomechanical aspects and the appropriate choice of therapeutic resources to promote effective and functional recovery of patients. An extensive bibliographic survey was carried out, in which studies whose objectives and content were aligned with the aims of this research were carefully selected. The methodology employed consisted of a wide-ranging review of the specialised literature on the subject in question using the databases of the Latin American and Caribbean Literature in Health Sciences, PublicMedline, Medical Literature Analysis and Retrieval System on Line, Scientific Electronic Library Online, Google Scholar and books. The review provided up-to-date information on the musculoskeletal structures involved in injuries, recovery strategies and available treatments. It highlighted the importance of a multidisciplinary and personalised approach to effective patient recovery, taking into account the particularities of each injury and the need for an individualised rehabilitation plan. It is hoped that this review will contribute to expanding knowledge in this area and help to improve the care provided.
本文试图对肌肉骨骼损伤及其康复过程提供一个全面综合的视角,强调了解所涉及的不同组织、生物力学方面以及适当选择治疗资源的重要性,以促进患者有效的功能康复。我们进行了广泛的文献调查,精心挑选了目标和内容与本研究目的一致的研究。采用的方法包括利用拉丁美洲和加勒比健康科学文献数据库、PublicMedline、在线医学文献分析和检索系统、科学电子图书馆在线、谷歌学术和书籍,对有关主题的专业文献进行了广泛的查阅。该综述提供了有关损伤所涉及的肌肉骨骼结构、恢复策略和现有治疗方法的最新信息。它强调了多学科和个性化方法对病人有效康复的重要性,同时考虑到了每种损伤的特殊性和制定个性化康复计划的必要性。希望本综述将有助于扩展该领域的知识,并帮助改善所提供的护理。
{"title":"Musculoskeletal Structures in Injuries, Recovery and Applicable Treatments: A Literature Review","authors":"Gabriela dos Santos Lopes, Ana Maria Cardoso de Freitas, Adaelson Machado Fonseca, Edwan Farias e Silva, Maria das Graças de Jesus Souza Queiroz, Paulo André Miranda Rodrigues, Rayane Lobato dos Santos, Reinaldo Miranda Barros, Vitor Hugo Auzier Lima","doi":"10.9734/jammr/2024/v36i75504","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i75504","url":null,"abstract":"This article sought to provide a comprehensive and integrated view of the process of musculoskeletal injury and its rehabilitation, highlighting the importance of understanding the different tissues involved, biomechanical aspects and the appropriate choice of therapeutic resources to promote effective and functional recovery of patients. An extensive bibliographic survey was carried out, in which studies whose objectives and content were aligned with the aims of this research were carefully selected. The methodology employed consisted of a wide-ranging review of the specialised literature on the subject in question using the databases of the Latin American and Caribbean Literature in Health Sciences, PublicMedline, Medical Literature Analysis and Retrieval System on Line, Scientific Electronic Library Online, Google Scholar and books. The review provided up-to-date information on the musculoskeletal structures involved in injuries, recovery strategies and available treatments. It highlighted the importance of a multidisciplinary and personalised approach to effective patient recovery, taking into account the particularities of each injury and the need for an individualised rehabilitation plan. It is hoped that this review will contribute to expanding knowledge in this area and help to improve the care provided.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":" 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141674984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitigating the Negative Impact of Social and Environmental Factors on Mental Well-being through Community-based Interventions 通过社区干预措施减轻社会和环境因素对心理健康的负面影响
Pub Date : 2024-07-03 DOI: 10.9734/jammr/2024/v36i75501
I. Folorunsho, N. M. Harry, Gibson Anugwom
Community-based interventions (CBI) effectively address the negative impact of social and environmental factors on mental well-being by leveraging community resources, strengths, and resilience. Successful examples, such as the Friendship Bench in Zimbabwe and the Community Reinforcement and Family Training (CRAFT) program, demonstrate the importance of community engagement and multi-sector partnerships in creating culturally responsive and sustainable mental health programs.
社区干预(CBI)通过利用社区资源、优势和复原力,有效地解决了社会和环境因素对心理健康的负面影响。津巴布韦的 "友谊长椅"(Friendship Bench)和 "社区强化与家庭培训"(Community Reinforcement and Family Training,CRAFT)项目等成功案例表明,社区参与和多部门合作对于创建具有文化响应性和可持续性的心理健康项目非常重要。
{"title":"Mitigating the Negative Impact of Social and Environmental Factors on Mental Well-being through Community-based Interventions","authors":"I. Folorunsho, N. M. Harry, Gibson Anugwom","doi":"10.9734/jammr/2024/v36i75501","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i75501","url":null,"abstract":"Community-based interventions (CBI) effectively address the negative impact of social and environmental factors on mental well-being by leveraging community resources, strengths, and resilience. Successful examples, such as the Friendship Bench in Zimbabwe and the Community Reinforcement and Family Training (CRAFT) program, demonstrate the importance of community engagement and multi-sector partnerships in creating culturally responsive and sustainable mental health programs.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in Spinal Alignment and Physiotherapy Treatment Applied to Scoliosis: A Systematic Literature Review 脊柱排列的变化和脊柱侧凸的物理治疗:系统性文献综述
Pub Date : 2024-07-03 DOI: 10.9734/jammr/2024/v36i75502
Talyta de Alcântara Lima, Maelly de Castro Cavalheiro, Jilvanda Diniz de Souza, Letícia Lobato Barbosa, Nayara Tainah Lobato da Silva, Nariane Rodrigues Pinheiro, Vitor Hugo Auzier Lima
Nowadays, the number of people complaining of back pain is increasing, but this pain is associated with scoliosis. However, scoliosis can be defined as the spine curving sideways, forming an "S" or "C" shape. However, there are several types of scoliosis: congenital, idiopathic, neuromuscular and degenerative. The most common is idiopathic scoliosis, which mostly affects children and adolescents, while congenital scoliosis is present at birth due to malformation of the spine. Neuromuscular scoliosis, on the other hand, affects the individual's neurological or muscular condition, followed by degenerative scoliosis, which develops in adulthood or the elderly and is caused by wear and tear on the spine. The aim of this study is to understand the forms of physiotherapy treatments applied to scoliosis. Subsequently, the physiotherapeutic treatments for this pathology include techniques such as RPG (Global Postural Reeducation), Pilates and waistcoats. RPG is a method that seeks to re-educate posture through stretching and muscle strengthening, while Pilates focuses on strengthening and improving flexibility. In addition, the back brace is used to align the spine during treatment. These treatments are aimed at a wide range of people, from children to teenagers, adults and the elderly, depending on the type and severity of the scoliosis. The benefits include improved posture, pain reduction and muscle strengthening. In conclusion, the results of physiotherapy treatment for scoliosis can vary from person to person, but many patients report a significant improvement in their quality of life, a reduction in the progression of the curvature and pain relief. Finally, treatment should be personalised and monitored by qualified professionals.
如今,抱怨背部疼痛的人越来越多,但这种疼痛与脊柱侧弯有关。脊柱侧弯的定义是脊柱向一侧弯曲,形成 "S "形或 "C "形。然而,脊柱侧弯有几种类型:先天性、特发性、神经肌肉性和退行性。最常见的是特发性脊柱侧弯,主要影响儿童和青少年,而先天性脊柱侧弯是由于脊柱畸形而在出生时就存在的。神经肌肉性脊柱侧弯则影响个人的神经或肌肉状况,其次是退行性脊柱侧弯,在成年期或老年人中出现,由脊柱磨损引起。本研究旨在了解脊柱侧弯症的物理治疗形式。随后,针对这种病症的物理治疗方法包括 RPG(全球姿势矫正)、普拉提和马甲等技术。RPG 是一种通过拉伸和增强肌肉来重新教育姿势的方法,而普拉提则侧重于增强和改善柔韧性。此外,在治疗过程中还会使用背架来调整脊柱。根据脊柱侧弯的类型和严重程度,这些治疗方法适用于从儿童到青少年、成人和老年人等各种人群。治疗的好处包括改善姿势、减轻疼痛和增强肌肉力量。总之,脊柱侧弯物理治疗的效果因人而异,但许多患者都表示生活质量明显改善,弯曲程度减轻,疼痛缓解。最后,治疗应个性化,并由合格的专业人员进行监测。
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引用次数: 0
The Most Cited Articles in Resinous Infiltrates: A Bibliometric Analysis 树脂浸润中被引用最多的文章:文献计量分析
Pub Date : 2024-07-01 DOI: 10.9734/jammr/2024/v36i75499
Ana Flávia César Guimarães, Júlia de Oliveira Rocha, Adriana da Silva Torres, Olga Beatriz Lopes Martins, Moisés de Matos Torres, Cíntia Tereza Pimenta de Araújo
Aims: To identify trends and growth in knowledge related to Resin Infiltrants, through a bibliometric review. Study Design:  Bibliometric review. Methodology: A search was carried out in the Clarivate Analytics Web of Science database, using the terms (infiltrative resin OR resin infiltration) AND (white spot lesions OR white spots OR WSL OR Enamel demineralization OR orthodon* OR defect* OR hypoplas* OR discolor * OR dental fluorosis OR tooth demineralization OR calcification, tooth OR tooth discoloration OR dental enamel). Paired selection of manuscripts was carried out. The initial search identified 599 articles. After comparing titles and abstracts, the 50 most cited manuscripts involving Resinous Infiltrants were listed in order of classification. Results: The most cited article in the top 50 was Frencken et al. in [1]. The earliest manuscript of this bibliometric analysis was published in 2001 by Robinson et al. in Caries Research and was cited 72 times, while two articles were the most recent, published in 2019 by Urquhart et al. in the Journal of Dental Research, it was cited 112 times and by Coelho Ased et al. in the Journal of Esthetic and Restorative Dentistry, cited 35 times. The citation distribution line shows high peaks in 2010 and 2012. The institutions that stood out the most were Charité Universitat Medizin Berlin, followed by Universitat zu Kiel. The main country was Germany. Among the main journals are the Journal of Dentistry and the publisher Elsevier. In total, 274 keywords were used. The period of 2010 was the period with the greatest concentration of publications and the most productive. Conclusion: The bibliometric review carried out in this study revealed the growing interest and research around the use of Resinous Infiltrants as an effective and minimally invasive alternative to address white spot lesions and tooth decay.
目的: 通过文献计量学综述,确定树脂浸润剂相关知识的发展趋势和增长情况。研究设计: 文献计量学综述。研究方法:在 Clarivate Analytics Web of Science 数据库中使用术语(浸润性树脂或树脂浸润)和(白斑病变或白斑或 WSL 或牙釉质脱矿或正畸*或缺陷*或畸形*或变色*或氟斑牙或牙齿脱矿或钙化,牙齿或牙齿变色或牙釉质)进行搜索。对稿件进行了配对筛选。初步检索发现了 599 篇文章。在对标题和摘要进行比较后,按照分类顺序列出了涉及树脂渗透剂的 50 篇引用率最高的手稿。结果:前 50 篇文章中被引用最多的是 Frencken 等人的文章[1]。本次文献计量分析中最早的一篇手稿是罗宾逊等人于2001年发表在《龋病研究》上的文章,被引用72次,而最近的两篇文章分别是乌尔克哈特等人于2019年发表在《牙科研究杂志》上的文章,被引用112次,以及科埃略-阿塞德等人发表在《牙科美容与修复杂志》上的文章,被引用35次。引文分布线显示,2010 年和 2012 年达到高峰。最突出的机构是柏林夏里特医学大学,其次是基尔大学。主要国家是德国。主要期刊包括《牙科学杂志》和出版商爱思唯尔。总共使用了 274 个关键词。2010 年是出版物最集中的时期,也是成果最丰硕的时期。结论本研究进行的文献计量学审查显示,人们对使用树脂渗透剂作为一种有效的微创替代方法来治疗白斑病变和蛀牙的兴趣和研究日益增长。
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引用次数: 0
A Case of Leiomyosarcoma of the Femoral Artery; Rare Location and Management at an Advanced Stage 一例股动脉横纹肌肉瘤;罕见的位置和晚期处理方法
Pub Date : 2024-07-01 DOI: 10.9734/jammr/2024/v36i75500
Hamadoun Traoré, Andy J. Kouanga, Mohammed Anouar Mokhlis, Mendes Papys, C. Elm’hadi, R. Tanz, Hassan Errihani
Vascular leiomyosarcomas are extremely rare tumours, accounting for less than 1% of all malignant tumours. Venous leiomyosarcomas occur five times more frequently than arterial leiomyosarcomas. These are most often found in the large vessels and less than 50% occur in the peripheral circulation. Median survival has not been quantified. It can be good if radical surgery is performed. Treatment, whatever the stage, requires multidisciplinary management. Surgery with en bloc resection remains the treatment of choice for localised disease; in patients with unresectable locally advanced or metastatic disease, systemic treatment with essentially palliative aims may be proposed. Anthracycline-based treatment is the standard first-line therapy. We report a case report of a 50-year-old female patient with local, pulmonary and bone relapse of an operated left femoral artery leiomyosarcoma in whom we undertook palliative mono-chemotherapy. Conclusion: Vascular leiomyosarcomas are extremely rare tumours, accounting for less than 1% of all malignant tumours. Median survival is dramatic for metastatic patients, with a median survival of 8 months, ranging from 5 to 20 months. Surgery remains the standard curative treatment for the localised stage; for stage 4, single chemotherapy is the treatment of choice.
血管网状肌肉瘤是一种极为罕见的肿瘤,在所有恶性肿瘤中所占比例不到 1%。静脉细肌瘤的发病率是动脉细肌瘤的五倍。这些肿瘤最常见于大血管,只有不到 50%的肿瘤发生在外周循环中。中位生存期尚未量化。如果进行根治性手术,生存率会很高。无论处于哪个阶段,治疗都需要多学科管理。对于无法切除的局部晚期或转移性疾病患者,可建议进行以姑息治疗为主的系统治疗。蒽环类药物治疗是标准的一线疗法。我们报告了一例 50 岁女性患者的病例,该患者曾接受过左股动脉白肌瘤姑息性单一化疗,术后出现局部、肺部和骨复发。结论血管细肌瘤是一种极为罕见的肿瘤,在所有恶性肿瘤中所占比例不到 1%。转移性患者的中位生存期很短,只有8个月,从5个月到20个月不等。手术仍然是局部阶段的标准根治性治疗方法;对于第四阶段,单一化疗是首选治疗方法。
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引用次数: 0
The Effect of Employment-Based Contingency on Treatment Enrollment, Retention, and Long-Term Abstinence among Individuals with Substance use Disorder: A Systematic Review 基于就业的应急措施对药物滥用障碍患者接受治疗、保持治疗和长期戒断的影响:系统回顾
Pub Date : 2024-05-22 DOI: 10.9734/jammr/2024/v36i65455
N. M. Harry, Ibrahim Folorunsho, Nnenna Okafor, Oluwatosin Arubuolawe, Gibson Anugwom
Background and Objective: Substance use disorders (SUD) remain a major public health concern and represent a significant cause of morbidity and mortality. Our goal in this study is to explore and determine the effect(s) of employment-based contingency (EBC) on enrolling SUD individuals into treatment, the rate of treatment adherence, and the rate of post-treatment abstinence. Methods: PubMed and Google Scholar search was conducted using the search terms ((substance use disorder) AND (unemployment)) OR (therapeutic workplace)), for randomized controlled trials (RCT) published between 2012 and 2022, reporting on participants between ages 18 and 65 years who use opioids, cocaine or alcohol. Results: Seven RCT which met the criteria and addressed the study objectives had a total of 389 participants. Three RCT of the seven with 203 participants found EBC to positively impact the rate of enrollment to treatment with 100%, 92%, and 100% enrollment rates in the respective studies. Three articles with 172 participants found a higher rate of treatment adherence and retention to treatment among EBC participants compared to the control group. There was more naltrexone-positive urine in the EBC group compared to control (72% vs. 21%, with a p-value of .01), and 74% (EBC) vs 26% (control) participants completed treatment. Four articles with 238 participants found that EBC improved the rate of abstinence by over 50%, which is double the rate among the control group without EBC. Conclusion: EBC is effective in improving SUD treatment enrollment, treatment adherence, and post-treatment abstinence, however, the efficacy may be dependent on how much is earned as an incentive.
背景和目的:药物使用障碍(SUD)仍然是一个重大的公共卫生问题,也是发病率和死亡率的一个重要原因。本研究的目的是探讨并确定就业应急方案(EBC)对 SUD 患者接受治疗、坚持治疗率以及治疗后戒断率的影响。研究方法使用检索词((药物使用障碍)和(失业))或(治疗性工作场所)对 PubMed 和 Google Scholar 进行检索。或(治疗工作场所))),搜索 2012 年至 2022 年间发表的随机对照试验(RCT),报告对象为 18 至 65 岁使用阿片类药物、可卡因或酒精的参与者。结果:有七项随机对照试验符合标准并实现了研究目标,共有 389 名参与者。在这七项研究中,有三项有 203 名参与者的研究发现,EBC 对治疗注册率有积极影响,注册率分别为 100%、92% 和 100%。三篇有 172 人参与的文章发现,与对照组相比,EBC 参与者的治疗依从率和治疗保持率更高。与对照组相比,EBC 组中纳曲酮阳性尿液的比例更高(72% 对 21%,P 值为 0.01),74%(EBC)对 26%(对照组)的参与者完成了治疗。四篇有 238 名参与者的文章发现,EBC 使戒断率提高了 50%以上,是未接受 EBC 治疗的对照组的两倍。结论:EBC 能够有效提高 SUD 治疗的注册率、治疗的依从性和治疗后的戒断率,但是,其效果可能取决于获得奖励的多少。
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引用次数: 0
Osteonecrosis Related to the use of Osteoporosis Medications: An Integrative Literature Review 与使用骨质疏松症药物有关的骨坏死:综合文献综述
Pub Date : 2024-05-21 DOI: 10.9734/jammr/2024/v36i65453
Rafaela Melo Santos, Edson Vinicius Santos Almeida, Naiara Lima Fagundes, Laila Eduarda Silva Pires, Luiz Eduardo de Góes Ladeia
Aims: Understand the relationship between bisphosphonates used in the treatment of osteoporosis and mandibular osteonecrosis, its outcomes, and implications for patient management, seeking to understand the best strategies for preventing and managing this condition. Study Design:  Integrative literature review. Methodology: The research methodology was outlined as exploratory and qualitative, aiming to provide a deeper understanding of the problem under study and generate hypotheses. Works published in the last 10 years (2014 to 2024) were used, including books, articles, periodicals, and online resources. For the selection of the sample, priority was given to works indexed in national and international journals, available in full. The electronic search was conducted in databases such as Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE), and Scientific Electronic Library Online (SciELO). The descriptors used were "Antiresorptive", "Bisphosphonate", "Mandible" and "Bone necrosis", registered in the Health Sciences Descriptors (DeCS), combined with the Boolean operators "AND" and "OR". The inclusion criteria for the selection of articles were to be original, addressing the theme of the study, to be indexed in the selected databases, written in Portuguese or English, and to be free of charge. Studies that were not related to the theme, duplicates and that did not fit into the proposed analysis period were excluded. Results: Through the studies surveyed, an association between the incidence of osteonecrosis and the use of osteoporosis drugs, such as bisphosphonates, especially osteonecrosis of the jaws (ONJ), was observed. Bisphosphonates, widely used in the treatment of osteoporosis, inhibit bone resorption, but their long-term use is associated with complications, including ONJ. Risk factors such as advanced age, long-term use of medications, comorbidities such as diabetes, and genetic predisposition have been identified. Conclusion: Management of ONJ involves conservative therapies and surgical procedures, which are especially effective when the condition is diagnosed early. On the other hand, therapeutic alternatives, such as photodynamic therapy, are being investigated, highlighting the need for controlled clinical trials to determine their efficacy.
目的:了解用于治疗骨质疏松症的双膦酸盐与下颌骨骨坏死之间的关系、其结果以及对患者管理的影响,寻求预防和管理这种疾病的最佳策略。研究设计: 综合文献综述。研究方法:研究方法概述为探索性和定性研究,旨在深入了解所研究的问题并提出假设。采用了过去 10 年(2014 年至 2024 年)发表的作品,包括书籍、文章、期刊和网络资源。在选择样本时,优先考虑在国内和国际期刊上有索引的作品,并提供全文。电子检索是在《拉丁美洲和加勒比健康科学文献》(LILACS)、《医学文献分析和检索系统在线》(MEDLINE)和《科学电子图书馆在线》(SciELO)等数据库中进行的。所使用的描述符为健康科学描述符(DeCS)中登记的 "抗还原剂"、"双膦酸盐"、"下颌骨 "和 "骨坏死",并结合布尔运算符 "AND "和 "OR"。选择文章的纳入标准是:原创、针对研究主题、被所选数据库收录、用葡萄牙语或英语撰写、免费。与主题无关的研究、重复的研究以及不符合拟议分析时间段的研究均被排除在外。结果通过所调查的研究发现,骨坏死的发病率与使用骨质疏松症药物(如双膦酸盐),尤其是颌骨坏死(ONJ)之间存在关联。双膦酸盐被广泛用于治疗骨质疏松症,可抑制骨吸收,但长期使用会引起并发症,包括颌骨坏死。已发现的风险因素包括高龄、长期使用药物、糖尿病等合并症以及遗传易感性。结论:ONJ 的治疗包括保守疗法和外科手术,在早期诊断时效果尤为显著。另一方面,目前正在研究光动力疗法等替代治疗方法,强调需要进行对照临床试验以确定其疗效。
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引用次数: 0
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Journal of Advances in Medicine and Medical Research
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