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Overlap Syndrome: Systemic Lupus Erythematosus and ANCA Vasculitis in a Case Report 重叠综合征:系统性红斑狼疮和 ANCA 血管炎的病例报告
Pub Date : 2024-05-10 DOI: 10.9734/jammr/2024/v36i55442
H. Benjelloun, A. Rattal, Afaf Amir, H. Harraz, N. Zaghba, K. Chaanoun, N. Yassine
Introduction: Microscopic polyangiitis is a systemic necrotising vasculitis that predominantly affects small-calibre vessels. It may be associated with systemic lupus erythematosus (SLE) as part of an overlap syndrome, but there are very few reports of this in the literature.     Case Report: We report the case of a 19-year-old patient admitted with moderate haemoptysis, epistaxis and petechial purpura revealing intra-alveolar haemorrhage with a strongly positive P-ANCA. In addition, blood tests for antinuclear antibodies and rheumatoid factor were positive, with renal involvement suggesting associated lupus as part of an overlap syndrome. Progression was good with corticoide and immunosuppressant treatment. Conclusion: The clinical presentation of overlap syndrome is rare and severe, with a dual immunological profile of antinuclear antibodies and neutrophil cytoplasm.
简介显微镜下多血管炎是一种全身性坏死性血管炎,主要影响小口径血管。作为重叠综合征的一部分,它可能与系统性红斑狼疮(SLE)伴发,但相关文献报道极少。 病例报告:我们报告了一例 19 岁患者的病例,该患者因中度咯血、鼻衄和瘀斑性紫癜入院,显示肺泡内出血,P-ANCA 呈强阳性。此外,血液中的抗核抗体和类风湿因子检测呈阳性,肾脏受累提示狼疮是重叠综合征的一部分。经皮质激素和免疫抑制剂治疗后,病情进展良好。结论重叠综合征的临床表现罕见而严重,具有抗核抗体和中性粒细胞胞浆的双重免疫学特征。
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引用次数: 0
The Changing Body: Importance of Adequate Adolescent Development 变化中的身体:青春期充分发育的重要性
Pub Date : 2024-05-08 DOI: 10.9734/jammr/2024/v36i55441
L. Ciampo, I. Ciampo
Adolescence is a phase of great physical, emotional and social transformations that human beings go through in the transition from childhood to adulthood. During this period, bodily changes and the maturation of emotions occur, which can cause difficulties in understanding on the part of adolescents. Body image, which is constructed at this stage of life, is one of the most worrying elements among adolescents, who try to follow the standards spread among their peers. This article presents some aspects of the evolution of adolescents, the influences on the formation of their body image and practices of modifying their appearance (tattoos and piercings), as well as suggestions so that those responsible for adolescents' health care can understand these conditions and act effectively in welcoming and guiding these individuals.
青春期是人类从童年向成年过渡的一个阶段,在生理、情感和社会方面都经历了巨大的转变。在这一时期,身体会发生变化,情感也会逐渐成熟,这可能会给青少年造成理解上的困难。在这一人生阶段形成的身体形象是青少年最担心的问题之一,因为他们试图追随同龄人之间传播的标准。本文介绍了青少年演变的一些方面、对其身体形象形成的影响以及修饰其外表(纹身和穿孔)的做法,并提出了一些建议,以便负责青少年保健的人员了解这些情况,并采取有效行动欢迎和引导这些人。
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引用次数: 0
Comparative Evaluation of Hydrogen Peroxide Levels in Patients with Periodontal Disease and Healthy Individuals–Pilot Study 牙周病患者和健康人体内过氧化氢水平的比较评估--试点研究
Pub Date : 2024-03-05 DOI: 10.9734/jammr/2024/v36i35392
Marcelo Fernandes de Castro, Yasmin Maria Tatico Chami, Jasiel de Oliveira, C. Perozini, W. Sendyk, Cristiane Yumi Koga-Ito, Debora Pallos, Marcia Hiromi Tanaka
Purpose: To assess the levels of hydrogen peroxide (H2O2) in crevicular fluid samples collected from patients with periodontal disease (PD) and periodontally healthy individuals. Methods: Crevicular fluid samples were collected from three diseased sites in 20 PD patients and from three healthy sites in 11 periodontally healthy patients (control). Plaque indices, probing depths, clinical attachment levels, and bleeding on probing were measured. Subsequently, the collected samples were categorized into three groups: a gingivitis group (n=8), a periodontitis group (n=12), and a control group (n=11). The quantification of H2O2 content within these samples was analyzed using an H2O2/peroxidase test kit. Results: Higher levels of H2O2 were found in the periodontitis group compared to group control and gingivitis (p<0.0001). Furthermore, the gingivitis group also shown elevated H2O2 levels compared to the control group (p<0.0001). Conclusions: The findings suggest that the severity of periodontal disease could be associated with elevated levels of H2O2 in gingival crevicular fluid. Hydrogen peroxide may potentially serve as a biomarker for disease progression or for products aimed at enhancing H2O2 release in periodontal treatment. However, further investigations with larger sample sizes and longitudinal designs are necessary to corroborate and expand upon these preliminary observations.
目的:评估从牙周病(PD)患者和牙周健康者采集的牙缝液样本中过氧化氢(H2O2)的水平。方法:采集牙周病患者和牙周健康者的牙缝液样本:从 20 名牙周病患者的三个病变部位和 11 名牙周健康患者(对照组)的三个健康部位采集牙缝液样本。测量牙菌斑指数、探诊深度、临床附着水平和探诊出血量。随后,收集的样本被分为三组:牙龈炎组(8 人)、牙周炎组(12 人)和对照组(11 人)。使用 H2O2/过氧化物酶检测试剂盒对这些样本中的 H2O2 含量进行定量分析。结果显示与对照组和牙龈炎组相比,牙周炎组的 H2O2 含量更高(P<0.0001)。此外,牙龈炎组的 H2O2 水平也高于对照组(P<0.0001)。结论研究结果表明,牙周病的严重程度可能与龈沟液中 H2O2 水平的升高有关。过氧化氢有可能成为疾病进展的生物标志物,或在牙周治疗中用于增强 H2O2 释放的产品。不过,要证实和扩展这些初步观察结果,还需要更多样本量和纵向设计的进一步研究。
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引用次数: 0
Colon Cancer with Mediastinal Metastasis 结肠癌纵隔转移
Pub Date : 2024-03-04 DOI: 10.9734/jammr/2024/v36i35388
Imad Taleb, Saad Mohammed Amine, Choukri Elmhadi, R. Tanz, Hassan Errihani
Background: The patient had a CAF (complete atrial fibrillation) as a comorbidity. Objective: The most common sites of colon cancer metastasis are the regional lymph nodes, liver, lung, bone and brain. The patient was 65 years old and had CAF as a comorbidity. She was consulted for a recent dyspnea evolving in a context of altered general state without any digestive sign. A thoracic scan showed a medial mass measuring 53*56*60mm. The lung biopsy revealed a muscular adenocarcinoma of colorectal origin with immunohistochemical expression of cytokeratin 7 (CK7), 20 and cytokeratin (CK) AE1/AE3, CDX2.The Pet Scan confirmed the existence of a hypermetabolic left anterosuperior medial mass in addition to a focal digestive hypermetabolism of the right colonic wall. A colonoscopy was performed and showed a tumor process in the right colon with a histological and immunohistochemical profile compatible with that of the mediastinal metastasis. The tumor was MSS (microsatellite stable), RAS (rat sarcoma) and BRAF(v-raf murine sarcoma viral oncogene homolog B1)wild type. The patient received a 3-month folfox-panitimumab combination with good tolerance and a partial response of about 50% on the metastasis. Conclusions: This case report provide a highly unusual instance of colon adenocarcinoma with extensive mediastinal lymph nodes metastasis.
背景:患者合并有完全性心房颤动(CAF)。目的:结肠癌最常见的转移部位是区域淋巴结、肝、肺、骨和脑:结肠癌最常见的转移部位是区域淋巴结、肝、肺、骨和脑。患者 65 岁,合并有完全性心房颤动。她因最近出现呼吸困难而就诊,当时全身状态改变,无任何消化道症状。胸部扫描显示有一个内侧肿块,大小为 53*56*60mm。肺部活检显示为结肠源性肌肉腺癌,免疫组化显示细胞角蛋白 7 (CK7)、20 和细胞角蛋白 (CK) AE1/AE3、CDX2。宠物扫描证实,除了右侧结肠壁存在局灶性消化代谢亢进外,左侧前上方内侧肿块也存在代谢亢进。结肠镜检查显示,右侧结肠内有一个肿瘤过程,其组织学和免疫组化特征与纵隔转移瘤相符。肿瘤为 MSS(微卫星稳定型)、RAS(大鼠肉瘤)和 BRAF(v-raf 小鼠肉瘤病毒癌基因同源物 B1)野生型。患者接受了为期3个月的folfox-帕尼单抗联合治疗,耐受性良好,转移灶部分反应约为50%。结论:本病例报告提供了一个非常罕见的结肠腺癌伴广泛纵隔淋巴结转移的病例。
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引用次数: 0
A Concept Analysis in Cultural Competency among Nurses Based on Walker and Avant Method 基于 Walker 和 Avant 方法的护士文化胜任能力概念分析
Pub Date : 2024-03-01 DOI: 10.9734/jammr/2024/v36i35386
Ma. Theresa Salinda, Glenda T. Moraño, Reggie Mae D. Jasmin, Wilfredo D. Quijencio, Jr., Myracle Isip-de Torres, Jacqueline Joy S. Paez, Gian Carlo P. De Jesus, Orlane Marybhell D. Dimaunahan, Daryl Jake S. Fornolles, Jennifer C. Padual, E. C. Mirafuentes
Background: Nursing serve as frontline in the delivery of care. Health care services focus on the complexity of cultural diversity to meet the multicultural clients therefore it necessary to have cultural competency in providing quality care from diverse background. Nurses must have that confidence in performing their duties, this includes plan of care that appropriate base on their patient beliefs or practices. Nurses with transcultural competency can overcome any challenges in serving the patient. Cultural skills showcase competency. In contrast, Nurses with low cultural competency tend to be avoidant to the patient in clinical assessment due to barriers like communication, lack of awareness and sensitivity in patient beliefs and practices.Purpose: The objective of this study is to investigate nurses in providing culturally congruent care for the patient with diverse background. Tailored with cultural competency in understanding patient situation in rendering services.Methods: The study utilize method by Walker and Avant in studying literature of different concepts of nurses pertaining to their nursing competency.  The process of concept analysis as follows [1] selection of concept [2] establishing the purpose [3] concept confirmation [4] identification of concept attributes [5] presentation of model case [6] provide constructing borderline, and other cases [7] identification of antecedent and consequences [8] Identification of empirical references. [1].Results: The research shows that nurses adhere responsibilities in providing care. It highlights knowledge and skills in the improvement of cross cultural health care. The use of concept such as cultural health, cultural education and cultural care serve as foundation in the concept of culturally competency. Nurses’ attributes such as cultural awareness, cultural knowledge and cultural communication skills in providing quality of care to the patient sharing  common goals and  creating meaningful partnership in health the  care plan.Conclusion: Cultural competence is an ability that is being developed gradually and that those who have already gained more experiences have been proven to be more aware and culturally competent than those with only some to little experiences.
背景:护理工作是提供护理服务的第一线。医疗保健服务注重文化多样性的复杂性,以满足多元文化客户的需求,因此有必要具备文化能力,为来自不同背景的客户提供优质护理服务。护士在履行职责时必须有信心,这包括根据病人的信仰或习俗制定适当的护理计划。具备跨文化能力的护士可以克服在为病人服务过程中遇到的任何挑战。文化技能彰显能力。相反,文化胜任能力低的护士在临床评估中往往会因沟通障碍、缺乏对病人信仰和习俗的认识和敏感性而回避病人。方法:本研究采用沃克-阿瓦德(Walker and Avra)的研究方法:本研究采用 Walker 和 Avant 的方法,研究与护士护理能力相关的不同概念的文献。 概念分析过程如下[1] 选择概念[2] 确定目的[3] 概念确认[4] 识别概念属性[5] 呈现示范案例[6] 提供构建边界和其他案例[7] 识别前因后果[8] 识别经验参考。[1].结果:研究表明,护士在提供护理服务时坚持责任。它强调了改善跨文化保健的知识和技能。文化健康、文化教育和文化护理等概念的使用是文化胜任能力概念的基础。护士的文化意识、文化知识和文化沟通技能等特质在为病人提供优质护理的过程中与病人分享共同的目标,并在护理计划中建立有意义的伙伴关系:文化胜任能力是一种逐步培养的能力,事实证明,那些已经积累了较多经验的人比那些只有一些或很少经验的人更有文化意识和文化胜任能力。
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引用次数: 0
Use of Post-Auricular Approach to Removal Anchors after Discopexy – Clinical Case Report 使用耳后入路在椎间盘突出术后取出锚 - 临床病例报告
Pub Date : 2024-03-01 DOI: 10.9734/jammr/2024/v36i35387
Andréa Juliana Luz Perdigão, Fabio Ricardo Loureiro Sato, Marília Coelho Oliveira Dutra Leal, R. G. Teixeira, C. Jodas
The mandibular temporomandibular joint (TMJ) is two diarthrodial ginglymus joints joined by a single bone, the mandible. Multiple approaches to TMJ are described in the literature due to the complexity of their exposure without damaging the noble structures in the region (facial nerve, temporal artery, and parotid gland) and causing aesthetic damage. This article will present a case report of a 21-year-old female patient. The post-auricular approach removed loose anchors in the right TMJ due to a fistula in the pre-auricular approach region. The post-auricular approach efficiently exposed TMJ and the healing, presenting superior aesthetic results compared to other TMJ approaches.
下颌颞下颌关节(TMJ)是由一块骨头(下颌骨)连接起来的两个二关节。由于暴露颞下颌关节的复杂性,在不损伤该区域高贵结构(面神经、颞动脉和腮腺)和造成美观损害的前提下,文献中描述了多种颞下颌关节的方法。本文将介绍一名 21 岁女性患者的病例报告。耳后入路切除了耳前入路区域瘘管导致的右侧颞下颌关节松动锚。耳后入路有效地暴露了颞下颌关节并使其愈合,与其他颞下颌关节入路相比,具有更佳的美学效果。
{"title":"Use of Post-Auricular Approach to Removal Anchors after Discopexy – Clinical Case Report","authors":"Andréa Juliana Luz Perdigão, Fabio Ricardo Loureiro Sato, Marília Coelho Oliveira Dutra Leal, R. G. Teixeira, C. Jodas","doi":"10.9734/jammr/2024/v36i35387","DOIUrl":"https://doi.org/10.9734/jammr/2024/v36i35387","url":null,"abstract":"The mandibular temporomandibular joint (TMJ) is two diarthrodial ginglymus joints joined by a single bone, the mandible. Multiple approaches to TMJ are described in the literature due to the complexity of their exposure without damaging the noble structures in the region (facial nerve, temporal artery, and parotid gland) and causing aesthetic damage. This article will present a case report of a 21-year-old female patient. The post-auricular approach removed loose anchors in the right TMJ due to a fistula in the pre-auricular approach region. The post-auricular approach efficiently exposed TMJ and the healing, presenting superior aesthetic results compared to other TMJ approaches.","PeriodicalId":506708,"journal":{"name":"Journal of Advances in Medicine and Medical Research","volume":"103 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140088870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Preferred Learning Styles of Clinical Medical Students at the Imo State University, Orlu, South East Nigeria 尼日利亚东南部奥尔卢伊莫州立大学临床医学专业学生的首选学习方式
Pub Date : 2024-03-01 DOI: 10.9734/jammr/2024/v36i35385
J. Azike, O. O. Enwere
Students have preferences in the way they internalize information. The VARK – an acronym for Visual, Aural, Read/Write and Kinesthetic questionnaire, tests students choices for preferred mode of internalizing information. The VARK questionnaire were administered to 400 level and 600 level medical students, a total of 123 of them participated in the study. Majority of them 89.4% preferred the multimodal mode of information reception while 10.56% were unimodal. A further analysis of the multimodals showed that females generally were quadmodal in their preferred sensory reception while the males were mainly trimodal. Overall, as regards individual VARK component, Kinesthetic was more common (29.8%) among males (31.6%) while Read/write was more common among the females (29.6%).
学生对信息的内化方式有偏好。VARK是视觉、听觉、读写和动觉问卷的首字母缩写,用于测试学生对信息内化方式的偏好选择。本研究对 400 级和 600 级医科学生进行了 VARK 问卷调查,共有 123 名学生参与。其中 89.4% 的学生偏好多模态信息接收模式,10.56% 的学生偏好单模态信息接收模式。对多模态的进一步分析表明,女性一般偏好四模态的感官接收方式,而男性则主要偏好三模态。总体而言,在 VARK 的各个组成部分中,男性(31.6%)更多采用 "动觉"(29.8%),而女性(29.6%)更多采用 "读写"。
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引用次数: 0
Epidemiological Profile of Adult Patients with Surgically Treated Intracranial Neoplasms 接受过手术治疗的颅内肿瘤成年患者的流行病学概况
Pub Date : 2024-03-01 DOI: 10.9734/jammr/2024/v36i35384
Rayane Toledo Simas, Laura Ferreira Moreira dos Santos, Bráulio Roberto Gonçalves Marinho Couto, François Dantas, Victor Kelles Tupy da Fonseca, Jarbas Carvalhaes, J. Raso, Fernando Luiz Rolemberg Dantas
Aims: The American Cancer Society,s estimates for brain and spinal cord tumors in the United States for 2023, include both adults and children,25,400 malignant tumors will be diagnosed. The objective of this study was to analyze the epidemiological profile, risk factors for complications and death in the in-hospital postoperative period, in addition to describing the histological type of intracranial tumors most frequently operated on in a private Brazilian institution. Study Design: Retrospective cohort study. Place and Duration of Study: Biocor Instituto/Rede D’Or, from 2018 to 2021 Methodology: Data were collected from the medical records of patients who underwent surgery for intracranial tumors. The variables analyzed in this study were demographic characteristics (age, sex, and comorbidities), histological types of primary and secondary neoplasms, anatomical location of the lesions, neurological deficits at admission and post-surgical treatment (at discharge), whether the surgery was urgent or elective, whether it was a reoperation, and whether there were deaths or complications during hospitalization. Results: Of 242 patients, 11 patients were excluded, and 231 patients were included in the analysis. The most common histological type was meningioma, accounting for 28% of cases. The histological type most associated with the risk of death was hemangioblastoma; however, it was also the histological type that presented the lowest incidence of cases. 39 patients (17%) had some complication in the in-hospital postoperative period, and 14 patients (6%) died. Conclusions: Meningiomas constituted the majority of cases, accounting for 28% of the sample. The rate of complications and mortality was higher when compared to data from the international literature because this series analyzed brain metastases together with the excision of primary tumors. Concerning in-hospital deaths, hemangioblastoma emerged as the histological type most associated with the risk of death. It is noteworthy, however, that hemangioblastoma also exhibited the lowest incidence among the various histological types.
目的:美国癌症协会估计,2023 年美国脑和脊髓肿瘤患者包括成人和儿童,将诊断出 2.54 万例恶性肿瘤。本研究的目的是分析流行病学概况、并发症的风险因素以及术后住院期间的死亡情况,同时描述巴西一家私立医疗机构中最常进行手术的颅内肿瘤的组织学类型。研究设计:回顾性队列研究。研究地点和时间:Biocor Instituto/Rede D'Or,2018年至2021年:从接受颅内肿瘤手术的患者病历中收集数据。本研究分析的变量包括人口统计学特征(年龄、性别和合并症)、原发性和继发性肿瘤的组织学类型、病变的解剖位置、入院时和手术治疗后(出院时)的神经功能缺损、手术是紧急手术还是择期手术、是否再次手术以及住院期间是否有死亡或并发症。结果:在 242 名患者中,11 名患者被排除在外,231 名患者被纳入分析。最常见的组织学类型是脑膜瘤,占病例总数的 28%。与死亡风险最相关的组织学类型是血管母细胞瘤,但这也是发病率最低的组织学类型。39名患者(17%)在术后住院期间出现并发症,14名患者(6%)死亡。结论是大多数病例为脑膜瘤,占样本的 28%。与国际文献数据相比,并发症发生率和死亡率较高,因为该系列分析的是脑转移瘤和原发肿瘤切除术。关于院内死亡,血管母细胞瘤是与死亡风险最相关的组织学类型。但值得注意的是,在各种组织学类型中,血管母细胞瘤的发病率也是最低的。
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引用次数: 0
Haematological Insight: An Epidemiological Study on Prevalence of Anaemia in Diverse Blood Groups within the Population of Hyderabad Sindh 血液透视:关于海得拉巴信德省不同血型人群贫血患病率的流行病学研究
Pub Date : 2024-02-15 DOI: 10.9734/jammr/2024/v36i25370
Syed Farhanuddin, Ahmed Hussain Suhag, Habib-ur-Rahman Chohan, Kiran Waheed, J. Warsi, Bilal Atique Arain, Syed Zain Ul Abdeen
dietary deficiencies, which is defined by the WHO as low Haemoglobin levels and low red cell death due to a deficiency of iron in the body. This is especially true for lower socioeconomic groups because of cultural influences and a lack of resources. All genders and age groups are affected by iron deficiency anemia (IDA), which can cause microcytic and hypochromic disease with a range of clinical consequences. According to many recent studies, there may be a connection between blood types and IDA, with those who belong to blood groups O and B perhaps at higher risk of developing the anemia. Confirmation of these links and comprehension of the underlying mechanisms need more study. Materials and Methods: This was a cross-sectional study, conducted at the emergency department of Liaquat University Hospital from June to August 2022 that involved 400 patients who were divided into two groups: a control group comprising 285 patients who were not suffering from iron deficiency anaemia and a study group comprising 415 patients suffering from iron deficiency anemia excluding those with other diseases. A formal consent preceded comprehensive clinical examinations, including blood pressure, pulse rate, and oxygen saturation measurements. Blood group determination employed the glass slide agglutination method, distinguishing A, B, AB, and O groups. Haemoglobin levels were assessed using Sahli's hemoglobinometer, while the complete blood picture was obtained by the blood CP report of the hospital laboratory. Statistical analyses, including Fischer's exact test, were performed using GraphPad 9 prism. Specificity/sensitivity, likelihood ratios, and odds ratios were calculated for further analysis. Conclusion: This study shows a significant relationship between various blood groups and the prevalence of anaemia in the population.
饮食缺乏症,世界卫生组织将其定义为因体内缺铁导致的血红蛋白水平低和红细胞死亡。由于文化影响和资源匮乏,社会经济地位较低的群体尤其如此。所有性别和年龄组都会受到缺铁性贫血(IDA)的影响,缺铁性贫血可导致小红细胞和低色素性疾病,并造成一系列临床后果。根据最近的许多研究,血型与 IDA 之间可能存在联系,血型为 O 型和 B 型的人患贫血的风险可能更高。对这些联系的确认和对潜在机制的理解还需要更多的研究。材料和方法:这是一项横断面研究,于 2022 年 6 月至 8 月在利亚卡特大学医院急诊科进行,共有 400 名患者参与,分为两组:对照组(包括 285 名非缺铁性贫血患者)和研究组(包括 415 名缺铁性贫血患者,不包括患有其他疾病的患者)。在获得正式同意后进行全面的临床检查,包括测量血压、脉搏和血氧饱和度。血型测定采用玻璃片凝集法,可区分 A、B、AB 和 O 血型。血红蛋白水平使用 Sahli 血红蛋白仪进行评估,全血象则通过医院实验室的血液 CP 报告获得。使用 GraphPad 9 prism 进行统计分析,包括费舍尔精确检验。计算了特异性/敏感性、似然比和几率,以便进一步分析。结论这项研究表明,各种血型与人群中的贫血症患病率之间存在明显关系。
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引用次数: 0
Haematological Insight: An Epidemiological Study on Prevalence of Anaemia in Diverse Blood Groups within the Population of Hyderabad Sindh 血液透视:关于海得拉巴信德省不同血型人群贫血患病率的流行病学研究
Pub Date : 2024-02-15 DOI: 10.9734/jammr/2024/v36i25370
Syed Farhanuddin, Ahmed Hussain Suhag, Habib-ur-Rahman Chohan, Kiran Waheed, J. Warsi, Bilal Atique Arain, Syed Zain Ul Abdeen
dietary deficiencies, which is defined by the WHO as low Haemoglobin levels and low red cell death due to a deficiency of iron in the body. This is especially true for lower socioeconomic groups because of cultural influences and a lack of resources. All genders and age groups are affected by iron deficiency anemia (IDA), which can cause microcytic and hypochromic disease with a range of clinical consequences. According to many recent studies, there may be a connection between blood types and IDA, with those who belong to blood groups O and B perhaps at higher risk of developing the anemia. Confirmation of these links and comprehension of the underlying mechanisms need more study. Materials and Methods: This was a cross-sectional study, conducted at the emergency department of Liaquat University Hospital from June to August 2022 that involved 400 patients who were divided into two groups: a control group comprising 285 patients who were not suffering from iron deficiency anaemia and a study group comprising 415 patients suffering from iron deficiency anemia excluding those with other diseases. A formal consent preceded comprehensive clinical examinations, including blood pressure, pulse rate, and oxygen saturation measurements. Blood group determination employed the glass slide agglutination method, distinguishing A, B, AB, and O groups. Haemoglobin levels were assessed using Sahli's hemoglobinometer, while the complete blood picture was obtained by the blood CP report of the hospital laboratory. Statistical analyses, including Fischer's exact test, were performed using GraphPad 9 prism. Specificity/sensitivity, likelihood ratios, and odds ratios were calculated for further analysis. Conclusion: This study shows a significant relationship between various blood groups and the prevalence of anaemia in the population.
饮食缺乏症,世界卫生组织将其定义为因体内缺铁导致的血红蛋白水平低和红细胞死亡。由于文化影响和资源匮乏,社会经济地位较低的群体尤其如此。所有性别和年龄组都会受到缺铁性贫血(IDA)的影响,缺铁性贫血可导致小红细胞和低色素性疾病,并造成一系列临床后果。根据最近的许多研究,血型与 IDA 之间可能存在联系,血型为 O 型和 B 型的人患贫血的风险可能更高。对这些联系的确认和对潜在机制的理解还需要更多的研究。材料和方法:这是一项横断面研究,于 2022 年 6 月至 8 月在利亚卡特大学医院急诊科进行,共有 400 名患者参与,分为两组:对照组(包括 285 名非缺铁性贫血患者)和研究组(包括 415 名缺铁性贫血患者,不包括患有其他疾病的患者)。在获得正式同意后进行全面的临床检查,包括测量血压、脉搏和血氧饱和度。血型测定采用玻璃片凝集法,可区分 A、B、AB 和 O 血型。血红蛋白水平使用 Sahli 血红蛋白仪进行评估,全血象则通过医院实验室的血液 CP 报告获得。使用 GraphPad 9 prism 进行统计分析,包括费舍尔精确检验。计算了特异性/敏感性、似然比和几率,以便进一步分析。结论这项研究表明,各种血型与人群中的贫血症患病率之间存在明显关系。
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引用次数: 0
期刊
Journal of Advances in Medicine and Medical Research
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