Burns最新文献

{"title":"Identifying risk and protective factors for burn wound infection: A retrospective study","authors":"Noah Borges ,&nbsp;Soetkin Rapol ,&nbsp;Ignace De Decker ,&nbsp;Liesbet De Bus ,&nbsp;Pieter Depuydt ,&nbsp;Stan Monstrey ,&nbsp;Karel E.Y. Claes ,&nbsp;Jan Fierens","doi":"10.1016/j.burns.2025.107826","DOIUrl":"10.1016/j.burns.2025.107826","url":null,"abstract":"<div><h3>Background</h3><div>Severe burn injuries remain associated with high morbidity and mortality due to secondary complications such as burn wound infections (BWIs). However, understanding of risk and protective factors for BWIs remains limited.</div></div><div><h3>Methods</h3><div>This retrospective cohort study included burn patients admitted to Ghent University Hospital between 2013 and 2023. Comorbidities, demographics, severity-of-illness scores, burn characteristics, and patient flow parameters were analysed. Penalised logistic regression and Cox survival analysis were performed. Patients without BWI served as controls.</div></div><div><h3>Results</h3><div>Among 492 burn patients, 68 (13.8 %) developed BWI, with a median onset of 4.7 days (IQR: 3.0–7.7). Penalised logistic regression identified vascular disease (aOR: 4.82, 95 % CI: [1.68–13.88], p = 0.005), age (p = 0.001), full-thickness burns (aOR: 3.26, 95 % CI: [1.55–6.89], p = 0.002) and TBSA (p &lt; 0.001) as independent risk factors. In Cox models, debridement performed early after admission (days 2–4) was associated with a lower hazard of BWI, with no significant difference from day 5 onwards.</div></div><div><h3>Conclusion</h3><div>This study underscores the association between vascular disease, age, TBSA, and full-thickness burns with BWI. Early debridement (within days 2–4 of admission) was significantly associated with reduced BWI hazard. These findings may provide valuable insights for refining early burn care and treatment protocols.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107826"},"PeriodicalIF":2.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Looking beyond the scalpel: Assessing patient risk factors for complications following surgical excision of hidradenitis suppurativa","authors":"Lily Zhu ,&nbsp;Iman F. Khan ,&nbsp;Rafael Felix P. Tiongco ,&nbsp;Jeffrey Khong ,&nbsp;Lisa C. Smith ,&nbsp;Rena Atayeva ,&nbsp;Tomer Lagziel ,&nbsp;Carisa M. Cooney ,&nbsp;Julie A. Caffrey","doi":"10.1016/j.burns.2025.107822","DOIUrl":"10.1016/j.burns.2025.107822","url":null,"abstract":"<div><h3>Introduction</h3><div>Hidradenitis suppurativa (HS) is a chronic inflammatory disease affecting intertriginous skin. Severe HS presents a reconstructive challenge due to high complication rates; however, risk factors for complications are understudied. This study examines patient-level risk factors for increased complications and operative techniques used at our institution.</div></div><div><h3>Methods</h3><div>We conducted an IRB-approved retrospective review of patients (≥18 years) who underwent primary or secondary wide local excision of HS between 12/1/2015–06/02/2022. Sociodemographic, intraoperative, and complication data were analyzed using descriptive statistics and Fisher’s exact tests. Multiple logistic regression was used to determine the association between patient demographic factors and occurrence of any complications. Significance was set at p &lt; 0.05.</div></div><div><h3>Results</h3><div>Of the 347 patients identified, 239 met inclusion criteria (median age 35 years, follow-up time 13 months). Most patients were Black (76 %) and non-Hispanic/non-Latino (95 %). Common HS risk factors included current smoking (20 %), former smoking (18 %), and diabetes (15 %). Patients were classified as Hurley Stage I (6 %), II (23 %), and III (45 %). Overall, 284 complications were reported, with more severe complications (e.g., flap/graft failure, hypertrophic granulation, keloid formation, hypertrophic scarring) predominantly occurring in Stage III. Complication rates of “other” complications differed significantly across Hurley stages I, II, and III (7 %, 2 %, 21 %, respectively; <em>p</em> &lt; 0.01), with Stage III having the highest rates. Unplanned reoperations also demonstrated significant differences across stages (27 %, 4 %, 18 %, respectively; <em>p</em> = 0.01). Regression analysis showed White race was significantly associated with lower complication risk (<em>p</em> = 0.039), while prior immunomodulator use increased risk (<em>p</em> = 0.02).</div></div><div><h3>Conclusions</h3><div>Disease severity and demographic factors significantly impact HS surgical outcomes. Patients in Hurley Stage III experienced higher complication rates. White race was associated with decreased complication risk while prior immunomodulator use was associated with increased complication risk, suggesting sociodemographic disparities and disease complexity contribute to poorer post-operative outcomes.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107822"},"PeriodicalIF":2.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of COVID-19 on patterns of burns evaluated in pediatric emergency departments","authors":"Stephanie Ruest ,&nbsp;Laurie H. Johnson ,&nbsp;Katherine T. Flynn-O’Brien ,&nbsp;Christina Georgeades ,&nbsp;Holly R. Hanson ,&nbsp;Andrew W. Kiragu ,&nbsp;Michelle T. Ruda ,&nbsp;Mark R. Zonfrillo ,&nbsp;Wendy J. Pomerantz","doi":"10.1016/j.burns.2025.107823","DOIUrl":"10.1016/j.burns.2025.107823","url":null,"abstract":"<div><h3>Background</h3><div>Fire- and burn-related injuries are among the top 10 causes of death for children &lt; 18 years in the United States and are associated with significant morbidity. Data regarding the impact of the COVID-19 pandemic on pediatric burns in emergency department (ED) settings are limited.</div></div><div><h3>Objective</h3><div>To examine differences in pediatric burn-related injury patterns before and during the COVID-19 pandemic.</div></div><div><h3>Methods</h3><div>This is a subanalysis of a multi-center cross-sectional study of 741,418 injury-related visits to 40 pediatric EDs for children &lt; 18 years. Burn visits were identified by International Classification of Diseases, 10th Revision (ICD-10) codes. Patient demographics and burn-related injury patterns for 3/17/2019–12/31/2019 (control period) vs. 3/15/2020–12/31/2020 (pandemic study period) were compared.</div></div><div><h3>Results</h3><div>Burn-related visits comprised 2.2 % (N = 12,908) of all injury visits. In 2020 there were 3.7 % fewer burn visits, but the proportion of burn visits relative to other injuries was higher (2.5 % vs. 2.0 %, p &lt; 0.001). There were significant differences in burn visits in 2020 by race (p &lt; 0.05) and ethnicity (p = 0.01), with higher proportions of White and non-Hispanic patients. There were significant differences in the geographic distribution of burn visits in 2020 (p &lt; 0.001) and significantly higher proportions of more urgent triage levels (p &lt;0.05) and trauma activations (p &lt; 0.05). Body region affected (p &lt; 0.01), intent (p &lt; 0.001) and mechanism (p &lt; 0.001) also differed significantly. A higher proportion were due to flames/fires and fewer due to hot objects.</div></div><div><h3>Conclusions</h3><div>Burns comprised a higher proportion of injury-related ED visits during the pandemic, with significant differences in patient demographics and injury patterns. These results can inform burn prevention education.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 2","pages":"Article 107823"},"PeriodicalIF":2.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chrysin promotes the survival of flaps through the TLR4/NF-κB/NLRP3 signaling pathway","authors":"Jiapeng Deng ,&nbsp;Kai Chen ,&nbsp;Xiaoying Jin ,&nbsp;Danna Chu ,&nbsp;Chaoyang Qi","doi":"10.1016/j.burns.2025.107828","DOIUrl":"10.1016/j.burns.2025.107828","url":null,"abstract":"<div><h3>Purpose</h3><div>Flap necrosis is a common postoperative complication primarily caused by ischemia-reperfusion injury and impaired angiogenesis. This study investigated the therapeutic effects and mechanisms of chrysin, a natural flavonoid compound extracted from medicinal plants including Oroxylum indicum, Scutellaria baicalensis, and Passiflora spp, on the survival of random skin flaps.</div></div><div><h3>Methods</h3><div>We employed network pharmacology to analyze chrysin's mechanism of action, predicting its therapeutic targets in ischemic diseases through cross-analysis of its potential targets with the pathophysiological mechanisms of ischemia-reperfusion injury. Molecular docking technology was used to simulate the optimal binding conformation and affinity between chrysin and its target receptors. Additionally, a modified McFarlane flap model was established in 36 Sprague-Dawley rats randomly divided into control, low-dose (10 mg/kg/day), and high-dose (40 mg/kg/day) groups (n = 12 each). Flap survival was evaluated 7 days postoperatively, along with assessments of TLR4/NF-κB/NLRP3 signaling pathway expression, tissue inflammation, oxidative stress levels, and blood perfusion.</div></div><div><h3>Results</h3><div>Chrysin treatment significantly improved flap survival rate in a dose-dependent manner. The mechanisms involved were 1) inhibiting activation of the TLR4/NF-κB/NLRP3 inflammatory signaling pathway; 2) reducing oxidative stress damage; and 3) promoting angiogenesis through upregulation of VEGF-A expression.</div></div><div><h3>Conclusions</h3><div>This study demonstrates that the plant-derived flavonoid chrysin improves flap survival through multiple mechanisms, including anti-inflammatory, antioxidant, and pro-angiogenic effects, providing a potential phytotherapeutic strategy for preventing and treating flap necrosis. These findings not only elucidate the pharmacological mechanisms of chrysin but also provide theoretical foundations for developing natural product-based adjuvant therapies in surgery.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107828"},"PeriodicalIF":2.9,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human platelet lysate–loaded collagen–poloxamer foam dressing for the management of deep partial-thickness burns","authors":"Marc A. Thompson ,&nbsp;David Larson ,&nbsp;Kim Brown ,&nbsp;Donald Brown ,&nbsp;Kristo Nuutila","doi":"10.1016/j.burns.2025.107825","DOIUrl":"10.1016/j.burns.2025.107825","url":null,"abstract":"<div><h3>Background</h3><div>Burn injuries remain a significant public health concern worldwide, leading to substantial morbidity, mortality, and healthcare costs. They are also common in military conflicts and have been a major concern in the ongoing war in Ukraine, often necessitating rapid evacuation and specialized medical care. There is a pressing need for effective burn management strategies that promote healing, reduce the risk of infection, and improve patient outcomes. In this study, we introduce a human platelet lysate (HPL)-containing poloxamer–collagen matrix, named AlloPLEX™️, for use in burn care.</div></div><div><h3>Methods</h3><div>AlloPLEX™ degradation, growth factor release, and bioactivity were characterized <em>in vitro</em>. <em>In vivo</em>, deep partial-thickness burns were induced on anesthetized pigs, with four treatment groups 1) high HPL (7.3 g) AlloPLEX™ (HHA), 2) low HPL (3.65 g) AlloPLEX™ (LHA), (3) no HPL AlloPLEX™ (Vehicle control, VC), and 4) Silverlon (SoC). Analgesia was provided prior to all surgical procedures. Punch biopsies were harvested on days 0 and 3; after euthanasia on day 28, the burns were excised for histologic analyses. Non-invasive imaging was utilized to assess burns macroscopically.</div></div><div><h3>Results</h3><div><em>In vitro</em>, it was shown that the foam is biodegradable, epidermal growth factor (EGF) and platelet derived growth factor (PDGF) release efficiently from the matrix, and it improves human mesenchymal stem cell (hMSC) proliferation. In vivo, the LHA group mitigated burn wound progression when compared to the SoC group. In terms of wound healing and quality of healing no differences were seen.</div></div><div><h3>Conclusions</h3><div>AlloPLEX™ is a novel bioactive and biodegradable foam dressing. It is lightweight and easy-to-use. The results demonstrated its potential as a burn care dressing.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107825"},"PeriodicalIF":2.9,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The lethal triad in patients with severe burns","authors":"Elisha Purcell ,&nbsp;Samara Rosenblum ,&nbsp;Biswadev Mitra ,&nbsp;Marc Schnekenburger","doi":"10.1016/j.burns.2025.107827","DOIUrl":"10.1016/j.burns.2025.107827","url":null,"abstract":"<div><h3>Background</h3><div>The lethal triad of trauma (acidemia, coagulopathy, and hypothermia) is associated with substantial morbidity and mortality. Patients with severe burn injuries, defined as &gt; 20 % total body surface area (TBSA), are one group of trauma patients at risk of developing this triad. However, there is currently limited evidence on how the lethal triad affects this cohort of patients.</div></div><div><h3>Objectives</h3><div>To describe the prevalence of the lethal triad in patients with severe burns on arrival to an adult burns service hospital. The secondary aim was to investigate potential factors associated with presence of the lethal triad.</div></div><div><h3>Methods</h3><div>Adult patients (&gt; 18 years of age) with severe burns (&gt; 20 %TBSA) admitted to a Victorian Adult Burns Service (VABS) tertiary hospital between January 1, 2019 and 31 December, 2023, were included in the study.</div></div><div><h3>Results</h3><div>From 158 patients identified through the VABS registry, 142 patients met inclusion criteria. Among 106 patients with available data, the lethal triad was present on arrival to hospital in 6 patients (5.7 %; 95 %CI: 2.1–11.9 %). Acidemia was present in 58 of 116 (50.0 %; 95 %CI: 40.6–59.4), coagulopathy in 18 of 125 (14.4 %; 95 %CI: 8.8–21.8) and hypothermia in 53 of 140 (37.9 %; 95 %CI: 29.8–46.4). Among patients with the lethal triad, all 6 patients (100 %) died, compared to 27 patients (27.0 %) without the lethal triad (odds ratio 21.0; 95 %CI: 2.91-&gt;99.9).</div></div><div><h3>Conclusions</h3><div>A small proportion of patients with severe burns presented to hospital with all three components of the lethal triad of trauma. Acidemia and hypothermia were more commonly observed when compared to coagulopathy. Recognition, prevention, and early management may result in improved outcomes.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107827"},"PeriodicalIF":2.9,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on \"Analyzing burns incidence trends in BRICS from 1990 to 2021: Findings from the Global Burden of Disease\"","authors":"Ruihan Zhang,&nbsp;Keqiang Ma,&nbsp;Shuyang Chen,&nbsp;Chenyu Zhao","doi":"10.1016/j.burns.2025.107824","DOIUrl":"10.1016/j.burns.2025.107824","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 2","pages":"Article 107824"},"PeriodicalIF":2.9,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145842458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects on health-related quality of life of therapeutic exercise in burn survivors: A systematic review and meta-analyses","authors":"Laëtitia Vigneron ,&nbsp;Javier Martín Núñez ,&nbsp;Jesús Zamora Tortosa ,&nbsp;Julia Raya Benítez ,&nbsp;Alejandro Heredia Ciuró ,&nbsp;Araceli Ortiz Rubio ,&nbsp;Marie Carmen Valenza","doi":"10.1016/j.burns.2025.107829","DOIUrl":"10.1016/j.burns.2025.107829","url":null,"abstract":"<div><h3>Background</h3><div>Burn injuries often result in long-term physical and psychological impairments that negatively impact health-related quality of life. Although therapeutic exercise is a key component of burn rehabilitation, its specific effects on health-related quality of life among adult burn survivors are unclear. The aim of this study was to systematically evaluate and meta-analyze the evidence on the effectiveness of therapeutic exercise in improving health-related quality of life among adult burn survivors.</div></div><div><h3>Methods</h3><div>We performed a systematic search of the PubMed, Scopus, Web of Science, PEDro, and Cochrane Library databases from their inception until January 2025. The research question was formulated using the PICOS model, and only clinical trials or randomized controlled trials involving adults were included. Therapeutic exercise interventions followed American College of Sports Medicine (ACSM) guidelines for either aerobic or resistance training, with usual care serving as the comparator. The Cochrane Risk of Bias Tool was used to assess risk of bias. The protocol was registered in PROSPERO (CRD42024527745).</div></div><div><h3>Results</h3><div>Seven studies involving 340 burn patients were included, and three studies were pooled for a meta-analysis using RevMan 5. Therapeutic exercise significantly improved burn-specific health-related quality of life (Short Form-36, the Burn Specific Health Scale–Brief, WHOQOL-BREF and EuroQol-5D) particularly in simple abilities (mean difference [MD] = 0.69; 95 % confidence interval [CI] = 0.26–1.12; p = 0.002) and affective aspects (MD = 1.63; 95 % CI = 1.00–2.26; p &lt; 0.001) of the Burn Specific Health Scale–Brief. However, no significant effect was observed in interpersonal relationships (p = 0.09). Substantial heterogeneity (I² = 83 %) was observed, requiring cautious interpretation of the results.</div></div><div><h3>Conclusions</h3><div>This systematic review and meta-analysis provide evidence that therapeutic exercise interventions significantly improve health-related quality of life in adult burn survivors. The findings are consistent across most health-related quality of life domains, in particular, the results of our meta-analysis show significant improvements in affect and simple skills.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 2","pages":"Article 107829"},"PeriodicalIF":2.9,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“A window of looking at the good, bad, and the stress:” A mixed-methods art therapy study with hospitalized adult burn patients","authors":"Bani Malhotra ,&nbsp;Linwood R. Haith Jr. ,&nbsp;Patricia A. Shewokis ,&nbsp;Johanna Czamanski-Cohen ,&nbsp;Minjung Shim ,&nbsp;Megan Stair-Buchmann ,&nbsp;Girija Kaimal","doi":"10.1016/j.burns.2025.107821","DOIUrl":"10.1016/j.burns.2025.107821","url":null,"abstract":"<div><h3>Background</h3><div>Improving psychosocial functioning in hospitalized burn survivors involves minimizing distress and pain and fostering emotion regulation. Art therapy could uniquely address the non-verbal aspects of distressing experiences, facilitating healthy emotional expression.</div></div><div><h3>Method</h3><div>This small N mixed-methods study examined the effect of 4-session art therapy intervention among 12 adult hospitalized burn patients on psychosocial outcomes of distress (Distress thermometer), affect (Positive and Negative Affect Schedule), change-perception (Patient Global Impression of Change), pain (Graphic Numeric Rating Scale), and self-expression and regulation (Self-Expression and Emotion Regulation in Art Therapy Scale, SERATS).</div></div><div><h3>Results</h3><div>Quantitative results using repeated ANOVA showed significant improvements in distress (F[1,9]=6.84, p = .028), positive affect (F[1,8]=5.5, p = 0.047), negative affect (F[1,8]=8.12, p = .022), and pain (F[1,9]=13.22, p = .005) across the four sessions. The global percentage change indicated positive trends in the outcomes. Changes did not reach statistical significance within-sessions. One-sample t-test showed a significant improvement in patients’ impression of change (t[10]=−4.183, two-sided p = .002) with mean responses approaching ‘much improved.’ Patients perceived art therapy as fostering emotional expression and regulation ‘often’ indicated by mean response scores approaching “4” for each item on SERATS. Thematic analysis elaborated on symptom management, expanded expression and perspective with art serving as tangible reminders, and creative engagement across sessions and with varied art media. Mixed-methods integration demonstrated congruent findings across art therapy sessions.</div></div><div><h3>Conclusion</h3><div>Art therapy can be a viable intervention to boost psychosocial health in hospitalized burn patients.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 2","pages":"Article 107821"},"PeriodicalIF":2.9,"publicationDate":"2025-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145842457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"optiTHERMM: A trainee-led international collaborative survey on perioperative patient body temperature monitoring and management for major burn injuries","authors":"Guy H.M. Stanley ,&nbsp;Majid Al-Khalil ,&nbsp;Cody C. Frear ,&nbsp;Glenn Boardman ,&nbsp;Lorna A. Burrows ,&nbsp;Skylar Paulich ,&nbsp;Jennifer C. Field ,&nbsp;Jonathon M. Pleat ,&nbsp;The optiTHERMM collaborators","doi":"10.1016/j.burns.2025.107817","DOIUrl":"10.1016/j.burns.2025.107817","url":null,"abstract":"<div><h3>Introduction</h3><div>Major burn injuries are often accompanied by disturbances in thermoregulation, with perioperative hypo- and hyperthermia presenting significant challenges for clinicians. Despite its implications for patient outcomes, research into perioperative thermoregulation and its influence on surgical decision-making remains limited.</div></div><div><h3>Methods</h3><div>Between February 2022 and June 2023, a 26-question survey was distributed to clinicians in the UK, Australia, and New Zealand to assess body temperature management practices for major burn patients. Respondents included burn surgeons, anaesthetists, and intensive care specialists, categorised by burn service complexity and patient demographics.</div></div><div><h3>Results</h3><div>A total of 148 responses were collected, with 96 from the UK (22 sites) and 52 from Australia and New Zealand (22 sites), achieving a response rate of 70 % among designated burn services (39/56). Most clinicians reported an absence (38 %) or lack of awareness (22 %) regarding local thermoregulation protocols. Hypothermia was more likely than hyperthermia to cause surgery delays, with 35° C cited as the most common threshold. No significant differences were found in temperature thresholds based on service complexity (p = 0.324), patient demographics (p = 0.67), or clinician roles (p = 0.238). Respondents from high-complexity hospitals reported significantly lower minimum and higher maximum preferred body temperature thresholds <em>during</em> surgery (p = 0.008 and p = 0.02, respectively). However, these thresholds did not differ significantly based on patient population (p = 0.259; p = 0.897) or clinician role (p = 0.409; p = 0.283). Methods used to monitor and manage body temperature were broadly consistent with those cited in other studies.</div></div><div><h3>Conclusions</h3><div>This international study represents the largest investigation of thermoregulation practices in major burns to date. While a consensus on optimal monitoring and modulation methods exists, there is considerable variability in practices and temperature preferences, highlighting the need for evidence-based guidelines to ensure consistent and optimal care.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 2","pages":"Article 107817"},"PeriodicalIF":2.9,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145842456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}