Burns最新文献

{"title":"Comments on: \"Establishing new education standards in burns – A scoping review\"","authors":"M. Vijayasimha , Rajesh Prasad Jayaswal","doi":"10.1016/j.burns.2025.107810","DOIUrl":"10.1016/j.burns.2025.107810","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107810"},"PeriodicalIF":2.9,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Use of selective decontamination of the digestive tract in burn patients – A European survey\"","authors":"Wenqi Lv, Xiaoyan Yan","doi":"10.1016/j.burns.2025.107809","DOIUrl":"10.1016/j.burns.2025.107809","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107809"},"PeriodicalIF":2.9,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effect of post-burn pruritus on patients' quality of life and experiences","authors":"Handan Aktas ,&nbsp;Zahide Tuncbilek ,&nbsp;Seyhan Hidiroğlu","doi":"10.1016/j.burns.2025.107808","DOIUrl":"10.1016/j.burns.2025.107808","url":null,"abstract":"<div><h3>Objective</h3><div>The study aims to determine the experiences of patients who suffer from post-burn pruritus and to evaluate the effect of pruritus on their quality of life.</div></div><div><h3>Method</h3><div>The research employed a mixed-methods approach, combining both quantitative and qualitative methods. The study was carried out at the burn center of a city hospital in Istanbul. Individuals aged 18 and over who suffered burns after April 15, 2019, and continued to experience pruritus complaints were included in the study. A total of 120 patients were included in the quantitative phase of the study. Data for the quantitative phase were collected using the Patient Information Form, the Pruritus Information Collection Form, the 12-Item Pruritus Severity Scale, and the Burn-Specific Health Scale between July 2019 and March 2020. The qualitative phase was conducted between August 2019 and February 2020, concurrently with the collection of quantitative data. In the qualitative phase, in-depth face-to-face interviews were carried out with 11 individuals using a Semi-Structured Interview Form.</div></div><div><h3>Results</h3><div>It was determined that the patients experienced pruritus ranging from mild to severe (3.00–19.00), with the average pruritus score indicating moderate severity (8.91 ± 3.90). Significant differences were found between groups in terms of pruritus severity based on length of hospital stay, depth of burn, total body surface area burned, burned body region, and the presence of grafts (p &lt; 0.05). In the in-depth interviews, it was found that burn patients struggled to cope with pruritus, that pruritus had an impact on their daily and family lives, and that it had physical, social, and psychological effects. Additionally, patients reported experiences related to the treatment of pruritus.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that as the severity, distribution, and persistence of pruritus increased, it was perceived by patients as an unbearable symptom; and that pruritus is a significant factor reducing the quality of life in burn patients. It is suggested that the proper evaluation of pruritus using objective measurement tools, the development of appropriate protocols for the treatment and follow-up of post-burn pruritus, and providing education and counseling services to help burn patients cope with pruritus could improve the quality of life for burn patients experiencing pruritus.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107808"},"PeriodicalIF":2.9,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BACH1 is stabilized by vitamin E and attenuates the formation of hypertrophic scar through the Wnt/β-catenin pathway","authors":"Wenkang Luan ,&nbsp;Shujun Fan ,&nbsp;Hanyi Jiang ,&nbsp;Dongwen Jiang ,&nbsp;Jinxiu Yang ,&nbsp;Leren He","doi":"10.1016/j.burns.2025.107807","DOIUrl":"10.1016/j.burns.2025.107807","url":null,"abstract":"<div><div>The molecular drivers behind the pathogenesis of hypertrophic scar (HS) formation have not been determined in a comprehensive manner. Aside from that, no consensus has been reached on the role of vitamin E in HS. For this reason, we have probed the causal effect of 2940 plasma proteins and 187 diets on HS through Mendelian randomization (MR). Colocalization analysis, summary-data-based MR (SMR), heterogeneity in dependent instruments (HEIDI), and MR phenome-wide association study (MR-PheWAS) were employed to identify the potential drug targets of HS. Human Protein Atlas, differential expression analysis, weighted co-expression network analysis (WGCNA) and single-cell analysis were utilized to confirm the key biomolecules in HS. To investigate the roles of critical molecules, we harvested primary fibroblasts and conducted validations using both in vitro and in vivo animal models. We put forth a viewpoint that the transcription factor BACH1 is causally related to the onset of HS, is a protective factor for HS, and may serve as its therapeutic target. We further determined that BACH1 reveals substantial expression in human skin tissue. BACH1 is under-expressed in HS tissues and fibroblasts. We confirmed that BACH1 and vitamin E act in an anti-scar role in primary fibroblasts and animal models through the Wnt/β-catenin pathway. Overall, our results demonstrate that BACH1 has an inhibitory effect on HS, and vitamin E attenuates the formation of HS by stabilizing BACH1.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107807"},"PeriodicalIF":2.9,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: \"Admission lymphopenia predicts risk of pneumonia and AKI in hospitalized burn injuries\"","authors":"Min Zhang ,&nbsp;Xingyi Yang","doi":"10.1016/j.burns.2025.107806","DOIUrl":"10.1016/j.burns.2025.107806","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107806"},"PeriodicalIF":2.9,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: \"Burn injury in obesity: Examination of the Burn Care Quality Platform’s (BCQP) available data on obese patients to determine burn-related outcomes\"","authors":"Mahta Moghaddam Ahmadi,&nbsp;Moein Moghaddam Ahmadi","doi":"10.1016/j.burns.2025.107801","DOIUrl":"10.1016/j.burns.2025.107801","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107801"},"PeriodicalIF":2.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term skin quality and scar formation after enzymatic debridement of deep-dermal burn wounds: A follow-up comparative study of Suprathel® and Jelonet®","authors":"Wolfram Heitzmann ,&nbsp;Mitja Mossing ,&nbsp;Maria von Kohout ,&nbsp;Yasser Alhujaili ,&nbsp;Jan Akkan ,&nbsp;Paul Christian Fuchs ,&nbsp;Rolf Lefering ,&nbsp;Jennifer Lynn Schiefer","doi":"10.1016/j.burns.2025.107803","DOIUrl":"10.1016/j.burns.2025.107803","url":null,"abstract":"<div><div>Recent advances in burn care have highlighted the benefits of enzymatic debridement in reducing long-term scarring by preserving viable dermal structures. Nexobrid®, a bromelain-based enzymatic debridement agent, has become an established treatment modality for deep-dermal burns, particularly of the hand, due to its selective action and tissue-sparing properties. After debridement, the choice of dressing critically influences inflammation, re-epithelialization, and ultimately scar quality and skin function. In clinical practice, Suprathel®, a synthetic copolymer membrane, and Jelonet®, a paraffin-impregnated gauze, are widely used. While Suprathel® offers improved pain control and patient comfort, Jelonet® remains a cost-effective standard.</div><div>Building on our previous intra-individual trial, which showed similar healing times but greater patient comfort with Suprathel®, this planned single-center, prospective long-term follow-up aims to address the lack of data on long-term scar quality and skin barrier function after enzymatic debridement. It includes the same 23 patients with deep-dermal hand burns who had received wound coverage with both Suprathel® and Jelonet® on comparable wound areas, assessed at 3, 6, and 12 months using objective instruments (Cutometer®, Mexameter®, Tewameter®, O2C®) and subjective scales (Vancouver Scar Scale, Patient and Observer Scar Assessment Scale).</div><div>Both dressings resulted in favorable and largely comparable scar outcomes over 12 months, with no significant differences in elasticity, perfusion, or overall clinical scar appearance. Subtle yet statistically significant differences in transepidermal water loss (p &lt; 0.01) and pigmentation (p &lt; 0.01) indicated a trend toward enhanced epidermal barrier restoration and reduced hypopigmentation in Suprathel®-treated areas, although these effects did not translate into perceptible clinical advantages.</div><div>These results confirm that both Suprathel® and Jelonet® are effective options for post-enzymatic debridement wound coverage, showing comparable long-term scar outcomes. The choice may reasonably depend on clinical workflow and dressing-management preferences, with Suprathel® remaining the standard in our burn center due to its reduced frequency of dressing changes.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107803"},"PeriodicalIF":2.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of emergency department visits for burn injuries in the United States, 2014–2023","authors":"Nicholas D. Soulakis ,&nbsp;Caroline Hensing ,&nbsp;Annabelle Shaffer ,&nbsp;David Gonzalez-Velez ,&nbsp;Ashley A. Peters ,&nbsp;Nathan Pecoraro ,&nbsp;Paul M. Arnold","doi":"10.1016/j.burns.2025.107802","DOIUrl":"10.1016/j.burns.2025.107802","url":null,"abstract":"<div><h3>Introduction</h3><div>Burn injuries cause significant morbidity and mortality. By better understanding the epidemiology and seasonality of such injuries, burn education and prevention efforts can be improved. The purpose of this investigation is to provide an update to the epidemiology of burn injuries in the United States (US).</div></div><div><h3>Methods</h3><div>This retrospective study analyzes data from the National Electronic Injury Surveillance System (NEISS) from 2014 to 2023. The NEISS collects data on emergency department visits from approximately 100 hospitals throughout the US. Data were analyzed using R version 4.4.3. to calculate annual burn estimates, injury rates, frequencies and acute periods of increased incidence.</div></div><div><h3>Results</h3><div>Between 2014 and 2023, emergency departments in the US treated an average of 206,856 burn injuries annually. These injuries occurred mainly in the home (66.8 %) and in males (53.1 %), with a peak incidence in children under 5 (20.6 %). This study found no significant increasing or decreasing trends in incidence over time; however, burn injury incidence and associated products fluctuated based on season, with an increased incidence occurring around July 4th.</div></div><div><h3>Conclusion</h3><div>Burn injuries significantly affect the US population. Public health and primary care workers may utilize information provided by this study to better target patient education on burn injury prevention.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107802"},"PeriodicalIF":2.9,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: \"Background pain, procedural pain, and optimism are associated with post-discharge pain in burn survivors\"","authors":"Shujun Qiu,&nbsp;Mingxian Chen","doi":"10.1016/j.burns.2025.107799","DOIUrl":"10.1016/j.burns.2025.107799","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107799"},"PeriodicalIF":2.9,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Historical note: The research strategy that halved postburn mortality","authors":"Leopoldo C. Cancio,&nbsp;Kaitlin A. Pruskowski","doi":"10.1016/j.burns.2025.107781","DOIUrl":"10.1016/j.burns.2025.107781","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"52 1","pages":"Article 107781"},"PeriodicalIF":2.9,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}