Japanese Dental Science Review最新文献_第3页

Salivary biomarkers for early detection of oral squamous cell carcinoma (OSCC) and head/neck squamous cell carcinoma (HNSCC) 口腔鳞状细胞癌（OSCC）和头颈部鳞状细胞癌（HNSCC）早期检测的唾液生物标志物。

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-01-08 DOI: 10.1016/j.jdsr.2024.12.002

Chen-xi Li , Shi-yang Deng

引用次数: 0

Micro- and nano-scale adhesion of oral bacteria to biomaterials using atomic force microscopy: A systematic review 用原子力显微镜观察口腔细菌与生物材料的微观和纳米级粘附：系统综述

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-03-17 DOI: 10.1016/j.jdsr.2025.03.002

Antonia Olivares , Valentina Barraza , Sebastian Aguayo

To evaluate the available evidence regarding in-vitro studies carried out with atomic force microscopy (AFM) to study the adhesion of oral bacteria under the research question: “Which adhesion parameters have been reported for oral bacteria attachment to surfaces following AFM experiments?”

This review was carried out following PRISMA guidelines. The Pubmed, Web of Science and Scopus databases were accessed and original articles reporting in-vitro findings on AFM-based oral bacteria adhesion experiments were included. Study selection and data extraction was performed by two independent researchers. Of the initial 249 screened articles, 24 were included in the final analysis.

Overall, the adhesion of oral bacteria to 12 different biomaterial surface types has been explored with AFM including soft materials, dental materials, and other materials. S. mutans was the most frequently studied bacterial species in its early attachment to biomaterials. Regarding AFM-based adhesion parameters, the maximum adhesion force, adhesion energy, rupture and contour lengths, and number of rupture events between oral bacteria and substrates have been quantified and reported.

Initial oral bacterial attachment to biomaterials is modulated by a range of cell, environmental, and surface-derived properties. Further research is needed to transfer this knowledge into the clinical setting.

为了评估利用原子力显微镜（AFM）研究口腔细菌粘附的体外研究的现有证据，研究问题是：“在原子力显微镜实验后，哪些粘附参数被报道为口腔细菌附着于表面？”这项审查是按照PRISMA的指导方针进行的。我们访问了Pubmed、Web of Science和Scopus数据库，并纳入了基于afm的口腔细菌粘附实验的体外实验结果的原创文章。研究选择和数据提取由两名独立研究人员进行。在最初筛选的249篇文章中，有24篇被纳入最终分析。总的来说，用AFM研究了口腔细菌对12种不同生物材料表面类型的粘附，包括软性材料、牙科材料和其他材料。变形链球菌是最常研究的细菌种类，在其早期附着于生物材料。关于基于afm的粘附参数，口腔细菌与底物之间的最大粘附力、粘附能、破裂和轮廓长度以及破裂事件数已被量化并报道。口腔细菌对生物材料的初始附着受到一系列细胞、环境和表面衍生特性的调节。需要进一步的研究将这些知识应用到临床环境中。

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引用次数: 0

Bioactivity and potential applications of surface pre-reacted glass-ionomer (S-PRG) filler-containing dental materials for geriatric oral health: A scoping review 含表面预反应玻璃离聚体（S-PRG）填充材料在老年口腔健康中的生物活性和潜在应用综述

IF 6.6 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-11-08 DOI: 10.1016/j.jdsr.2025.11.002

Thein Soe , Akiho Sunami , Okkar Kyaw , Keita Hatano , Manabu Kanazawa , Masanao Inokoshi

This scoping review explores the potential applications of surface pre-reacted glass-ionomer (S-PRG) filler-containing dental materials in geriatric dentistry. A literature search across four databases (CINAHL, MEDLINE, PubMed, and Web of Science) identified 324 articles, of which 51, including 39 in vitro, 1 in situ, 1 preclinical, and 10 clinical studies, met the inclusion criteria. These reports demonstrate that, across the domains of preventive, restorative, endodontic, and prosthodontic dentistry, S-PRG filler-containing materials consistently exhibit bioactive properties, such as fluoride-release and recharge, multi-ion release, acid-buffering, anti-demineralization, remineralization, and antimicrobial activity. In preventive dentistry, S-PRG filler-based dentin coating agents, varnishes, and toothpastes show promising effects for caries prevention and periodontal pathogen control. In restorative dentistry, S-PRG filler-based composites and adhesives demonstrate bioactivity and favorable long-term clinical results. In prosthodontics, S-PRG filler-based denture base resins, tissue conditioners, and denture adhesives offer protective and antimicrobial effects. These multifunctional properties support the roles of S-PRG filler-containing dental materials as both preventive and therapeutic agents for managing common oral health issues in older adults, including root caries, periodontal disease, and denture stomatitis. Further clinical and longitudinal studies are needed to confirm their effectiveness and guide their use in geriatric care.

本文综述了含表面预反应玻璃离子聚合物（S-PRG）填充材料在老年牙科中的潜在应用。在四个数据库（CINAHL、MEDLINE、PubMed和Web of Science）中检索了324篇文献，其中51篇符合纳入标准，包括39项体外研究、1项原位研究、1项临床前研究和10项临床研究。这些报告表明，在预防、修复、牙髓和修复等牙科领域，含S-PRG填料的材料始终表现出生物活性，如氟化物释放和充电、多离子释放、酸缓冲、抗脱矿、再矿化和抗菌活性。在预防性牙科中，S-PRG填料基牙本质涂层剂、清漆和牙膏在预防龋齿和控制牙周病原体方面显示出良好的效果。在牙科修复中，S-PRG填料基复合材料和粘接剂显示出生物活性和良好的长期临床效果。在口腔修复学中，S-PRG填料基义齿基托树脂、组织调节剂和义齿粘接剂具有保护和抗菌作用。这些多功能特性支持含S-PRG填料的牙科材料作为预防和治疗老年人常见口腔健康问题的药物，包括牙根龋齿、牙周病和假牙口炎。需要进一步的临床和纵向研究来证实其有效性并指导其在老年护理中的应用。

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引用次数: 0

Multifaceted characterization of antibacterial resin composites: A scoping review on efficacy, properties, and in vivo performance 抗菌树脂复合材料的多方面表征：对其功效、性能和体内性能的综述

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-06-04 DOI: 10.1016/j.jdsr.2025.05.003

Reinaldo Adelino de Sales-Junior , Mariana Silva de Bessa , Francisca Jennifer Duarte de Oliveira , Bárbara Faria de Sá Barbosa , Kaiza de Sousa Santos , Michael Owen , Victor Pinheiro Feitosa , Boniek Castillo Dutra Borges

This scoping review aimed to collect, analyze, synthesize, and interpret the current data concerning antibacterial resin-based composites. The study followed the recommendations of the Joanna Briggs Institute and PRISMA Extension for Scoping Reviews. The searches were conducted in the PubMed, Embase, Web of Science, and Scopus databases. Studies evaluating efficacy, physical and chemical properties, cytotoxicity, and preventive effect against recurrent caries lesions provided by antibacterial resin-based composites published in the last 5 years and without language restriction were included. Fifty-three papers were analyzed. Only in vitro, in situ, and animal studies were published. The DMAHDM (dimethylaminohexadecyl methacrylate) was the most prevalent antibacterial agent in the resin composites and showed efficacy, did not increase cytotoxicity, nor jeopardize chemical and physical properties. The most used biofilm model and the test to evaluate the antibacterial effect was Streptococcus Mutans and the Colony Forming Unit Count. Antibacterial resin-based composites have performed exceedingly well in the large number of in vitro studies evaluated. However, clinical trials assessing the prevention of recurrent caries are absent and need to be further conducted to assure that using an antibacterial resin composite is a valid way to avoid restoration replacement due to recurrent caries.

本综述旨在收集、分析、合成和解释目前有关抗菌树脂基复合材料的数据。这项研究遵循了乔安娜布里格斯研究所和PRISMA扩展范围审查的建议。检索在PubMed、Embase、Web of Science和Scopus数据库中进行。本文纳入了近5年来发表的无语言限制的抗菌树脂基复合材料的疗效、理化性质、细胞毒性和预防龋齿复发作用的研究。分析了53篇论文。仅在体外、原位和动物研究中发表。DMAHDM（二甲氨基十六烷基甲基丙烯酸酯）是树脂复合材料中最常用的抗菌剂，具有良好的抗菌效果，不会增加细胞毒性，也不会损害化学和物理性能。最常用的生物膜模型和评价抗菌效果的试验是变形链球菌和菌落形成单位计数。抗菌树脂基复合材料在大量体外研究中表现非常好。然而，临床试验评估预防复发性龋齿缺乏，需要进一步进行，以确保使用抗菌树脂复合材料是一种有效的方法，以避免因复发性龋齿而更换修复体。

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引用次数: 0

Optimizing titanium dioxide-functionalized polymethyl methacrylate (PMMA-TiO₂) for dental applications: A systematic review on physicochemical parameters and antimicrobial outcomes 优化牙科应用的二氧化钛功能化聚甲基丙烯酸甲酯（PMMA-TiO 2）：理化参数和抗菌效果的系统综述

IF 6.6 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-09-30 DOI: 10.1016/j.jdsr.2025.09.002

Victor Melo-Soares, Andréa Cândido dos Reis, Mariana Lima da Costa Valente

Introduction

Polymethyl methacrylate (PMMA) resins are widely used in dental prostheses due to their excellent physical, mechanical, and aesthetic properties. However, their susceptibility to microbial colonization can compromise oral and systemic health. Titanium dioxide (TiO₂), with its photocatalytic activity, has gained attention for its antimicrobial potential. This systematic review investigates how the physicochemical properties of TiO₂ affect its antimicrobial efficacy in PMMA-TiO₂ composites, aiming to optimize their performance and clinical effectiveness.

Methods

PubMed, Embase, Scopus, ScienceDirect, Web of Science, Google Scholar, and ProQuest were searched in October 2024. Articles were selected in two stages by two blinded researchers based on predefined eligibility criteria. Risk of bias was assessed using the RobDEMAT tool.

Results

A comprehensive search identified 1464 articles, which were screened by title and abstract according to inclusion criteria. Of the 28 studies selected for full-text review, 24 were included in this systematic review, all of which were in vitro studies. Due to the high heterogeneity of the selected studies, which prevented statistical analysis of the data, a descriptive analysis was performed.

Conclusions

The balance between concentration, size, crystallinity, and surface morphology can enhance TiO₂ photocatalytic activity and reduce microbial adhesion. Synthesis and functionalization strategies can overcome limitations, expanding the clinical applicability, efficiency, and durability of PMMA-TiO₂ composites.

聚甲基丙烯酸甲酯（PMMA）树脂因其优异的物理、机械和美学性能而广泛应用于口腔修复中。然而，他们对微生物定植的易感性会损害口腔和全身健康。二氧化钛（TiO 2）具有光催化活性，其抗菌潜力备受关注。本文研究了二氧化钛在pmma -二氧化钛复合材料中的理化性质对其抗菌效果的影响，旨在优化其性能和临床效果。方法于2024年10月检索spubmed、Embase、Scopus、ScienceDirect、Web of Science、谷歌Scholar和ProQuest。两名盲法研究人员根据预先确定的资格标准，分两个阶段选择文章。使用RobDEMAT工具评估偏倚风险。结果综合检索到文献1464篇，根据纳入标准按标题和摘要筛选。在入选全文综述的28项研究中，有24项纳入了本系统综述，均为体外研究。由于所选研究的高度异质性，这阻碍了数据的统计分析，因此进行了描述性分析。结论浓度、粒径、结晶度和表面形貌之间的平衡可以提高tio2光催化活性，减少微生物粘附。合成和功能化策略可以克服局限性，扩大PMMA-TiO 2复合材料的临床适用性，效率和耐久性。

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引用次数: 0

Temporomandibular disorders: A new list of key points to summarize the standard of care 颞下颌疾病：总结护理标准的新要点。

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2024-12-19 DOI: 10.1016/j.jdsr.2024.12.001

Daniele Manfredini, Steven S. Bender, Birgitta Häggman-Henrikson, Justin Durham, Charles S. Greene

This letter is being sent to editors of major dental journals around the world. Attached to it is an Announcement that summarizes a recently published position paper which deals with the topic of standards of care for Temporomandibular Disorders (TMDs). That paper, entitled “Temporomandibular disorders: INfORM/IADR key points for good clinical practice based on standard of care”, was developed by a group of expert researchers and clinicians over a one-year period. The full paper describing the outcome of this project was published in CRANIO – The Journal of Craniomandibular and Sleep Practice (1), and is available as an open access paper at the following link. https://www.tandfonline.com/doi/full/10.1080/08869634.2024.2405298?src=exp-la

这封信正寄给世界各地主要牙科杂志的编辑。附件是一份公告，总结了最近发表的一份关于颞下颌疾病（TMDs）护理标准的立场文件。这篇题为“颞下颌疾病：基于标准护理的良好临床实践的INfORM/IADR关键点”的论文是由一组专家研究人员和临床医生在一年的时间内编写的。描述该项目的完整论文发表在CRANIO - The Journal of Craniomandibular and Sleep Practice(1)上，并可通过以下链接作为开放获取论文。https://www.tandfonline.com/doi/full/10.1080/08869634.2024.2405298?src=exp-la。

引用次数: 0

A systematic review of metastatic lesions to the oral and maxillofacial regions among Japanese people 日本人口腔颌面部转移性病变的系统回顾

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-06-25 DOI: 10.1016/j.jdsr.2025.06.001

Seiji Asoda , Takazumi Yasui , Kenta Tanaka , Katsuhiro Onizawa , Hiromasa Kawana , Taneaki Nakagawa

This review aimed to integrate the available data published in the literature on metastatic lesions in the oral and maxillofacial region (MOMR) and to produce an updated comprehensive analysis of its clinical characteristics, treatment, and prognosis. An electronic database search was conducted for articles concerning MOMR in Japan. The incidence and characteristics of MOMR were investigated, and the survival time was analyzed. This systematic review identified 211 studies, including 356 cases. There was a male predominance (n = 250/70.2 %) and the mean age at the diagnosis was 62.1 (range, 4–91) years old. The most common primary site was the lungs (n = 104/29.2 %). Oral metastasis sites were equally frequent in the jawbone (n = 182/51.1 %) and soft tissue (n = 174/48.9 %). Among these, the mandible and gingiva were the most common. The most common clinical presentation was a nodule (n = 317/90.3 %). The presence of metastases to other organs (P = 0.009) and uncontrolled primary lesions (P < 0.001) was associated with a shortened survival. This systematic review provides important insights into the clinical features, diagnosis, and treatment of MOMR in Japan and will assist clinicians in their appropriate management.

本综述旨在整合已发表的关于口腔颌面区（MOMR）转移性病变的文献资料，并对其临床特征、治疗和预后进行最新的综合分析。对日本有关MOMR的文章进行了电子数据库检索。研究了MOMR的发生率和特点，并分析了生存时间。本系统综述确定了211项研究，包括356例病例。男性居多（n = 250/70.2 %），平均诊断年龄为62.1岁（范围4-91岁）。最常见的原发部位为肺部（n = 104/29.2 %）。口腔转移部位在颌骨（n = 182/51.1 %）和软组织（n = 174/48.9 %）同样常见。其中以下颌骨和牙龈最为常见。最常见的临床表现为结节（n = 317/90.3 %）。转移到其他器官（P = 0.009）和未控制的原发病变（P <； 0.001）的存在与生存期缩短相关。本系统综述为日本MOMR的临床特征、诊断和治疗提供了重要的见解，并将协助临床医生进行适当的管理。

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引用次数: 0

Utilization of cellulose nanofiber in dental applications: A systematic review of in vitro evidence 纤维素纳米纤维在牙科应用中的应用：体外证据的系统综述

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-05-31 DOI: 10.1016/j.jdsr.2025.05.002

Kunhua Yang , Alexander Patera Nugraha , Junduo Chen , Hui Yang , Jingyu Wang , Juan Ramón Vanegas Sáenz , Guang Hong

This systematic review aimed to determine how cellulose nanofiber (CNF) enhance the mechanical properties, biocompatibility, and functional versatility of dental materials, based on in vitro evidence. A systematic review protocol was developed according to PRISMA 2020. The literature search was conducted using MEDLINE/PubMed, Scopus, Web of Science, Scopus, and Embase for English-language publications with no date restrictions, yielding 180 publications. After removing duplicates, 150 remained, from which 23 were evaluated in full. 17 in vitro studies met the inclusion criteria, of which 13 had a low risk of bias, 4 had a moderate risk, and none had a high risk. Across all included investigations, CNF consistently improved mechanical performance, particularly flexural and compressive strength, while maintaining or enhancing biocompatibility in various cell culture models. CNF’s nanofibrillar structure and modifiable surface chemistry also expanded its functional versatility, enabling applications such as drug encapsulation and targeted antimicrobial delivery. Overall, CNF emerges as a promising biomaterial for modern dentistry, offering superior mechanical reinforcement, favorable cell responses, and wide-ranging functional modifications. Further in vivo research and clinical trials are necessary to confirm its long-term safety and efficacy, thereby facilitating the translation of these in vitro findings into standard dental practice.

本系统综述旨在确定纤维素纳米纤维（CNF）如何增强牙科材料的机械性能、生物相容性和功能通用性，基于体外证据。根据PRISMA 2020制定了系统审查方案。文献检索使用MEDLINE/PubMed、Scopus、Web of Science、Scopus和Embase对无日期限制的英文出版物进行检索，共检索到180篇出版物。去除重复项后，剩下150项，其中23项被完全评估。17项体外研究符合纳入标准，其中13项为低偏倚风险，4项为中等偏倚风险，无高风险。在所有包括的研究中，CNF持续改善机械性能，特别是弯曲和抗压强度，同时保持或增强各种细胞培养模型的生物相容性。CNF的纳米纤维结构和可修饰的表面化学也扩展了其功能的多功能性，使其能够应用于药物封装和靶向抗菌药物输送等领域。总的来说，CNF作为一种有前途的现代牙科生物材料，提供优越的机械加固，有利的细胞反应和广泛的功能修饰。进一步的体内研究和临床试验是必要的，以确认其长期安全性和有效性，从而促进这些体外研究结果转化为标准的牙科实践。

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引用次数: 0

Efficacy of adjunctive periodontal interventions in non-surgical periodontal therapy for Stage III/IV Grade C periodontitis: A systematic review and network meta-analysis 辅助牙周干预在非手术牙周治疗III/IV期C级牙周炎中的疗效：一项系统综述和网络荟萃分析

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-07-14 DOI: 10.1016/j.jdsr.2025.07.001

Shih-Ying Lin , Hung-Ying Lin , Jui-Sheng Sun , Jenny Zwei-Chieng Chang

This study evaluates the effectiveness of adjunctive therapies combined with non-surgical periodontal treatment for Stage III/IV Grade C periodontitis, focusing on pocket depth (PD) reduction, clinical attachment level (CAL) gain, and adverse events. A systematic review and network meta-analysis were conducted, including randomized controlled trials up to September 2024. Inconsistencies and publication bias were detected, prompting sensitivity analyses and effectiveness rankings of adjunctive therapies. Data from 50 studies were included, with 45 entered into network meta-analysis, covering 24 interventions and 1431 patients. Compared to scaling and root planing (SRP) alone, adjunctive systemic lincosamides with nitroimidazole (Mac/Linc+Nitro-S) demonstrated the greatest PD reduction, followed by local statins (Statins-L) in the short term (≤3 months). Statins-L also provided the highest CAL gain. In the medium term (4–6 months), Statins-L remained the most effective, followed by bisphosphonates. For long-term (>6 months) follow-up, where fewer treatment approaches were available, Nitro-S achieved the most significant PD reduction and CAL gain, followed by Mac/Linc-S. Adverse effects were mild and self-limiting. Despite promising findings, inconsistencies in CAL outcomes and potential publication bias highlight the need for further research to confirm long-term safety and efficacy.

本研究评估了辅助疗法结合非手术牙周治疗治疗III/IV期C级牙周炎的有效性，重点关注袋深度（PD）减少、临床附着水平（CAL）增加和不良事件。进行了系统评价和网络荟萃分析，包括截至2024年9月的随机对照试验。发现不一致和发表偏倚，提示辅助治疗的敏感性分析和有效性排名。纳入了50项研究的数据，其中45项进入网络荟萃分析，涵盖24项干预措施和1431名患者。与单纯的刮治和刨根（SRP）相比，辅助全身lincoamide与硝基咪唑（Mac/Linc+硝基- s）显示出最大的PD降低，其次是局部他汀类药物（他汀- l）在短期内（≤3个月）。他汀类药物l也提供了最高的CAL增益。在中期（4-6个月），他汀- l仍然是最有效的，其次是双膦酸盐。在长期（6个月）随访中，可用的治疗方法较少，硝基- s达到最显著的PD降低和CAL增加，其次是Mac/林肯- s。不良反应轻微且具有自限性。尽管有很好的发现，但CAL结果的不一致性和潜在的发表偏倚突出了进一步研究以确认长期安全性和有效性的必要性。

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引用次数: 0

Nanoidentification in endodontics: Bibliometric analysis and comprehensive review on the basis of characterisation research by Nano-computed tomography imaging 牙髓学中的纳米鉴定：文献计量学分析和基于纳米计算机断层成像表征研究的综合综述

IF 5.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Japanese Dental Science Review

Pub Date : 2025-12-01 Epub Date: 2025-03-24 DOI: 10.1016/j.jdsr.2025.03.003

Olcay Özdemir , Sena Kaşıkçı , Turkan Kopac

Nanoimaging, crucial in endodontics, has advanced, leading to more effective and less invasive treatments. Nano-computed tomography (nano-CT) is an advanced imaging technique to evaluate bone structures or gaps in filling materials, providing submicrometer spatial resolution due to smaller focal points and voxels, higher signal-to-noise ratios, and higher tube voltages and powers compared to conventional devices, improving dental imaging precision and safety by producing detailed images with minimal radiation exposure. This study conducted a bibliometric analysis on nano-CT imaging as a nano identification tool in endodontics. Using various tools and methods, it evaluated progress and trends in nano-CT, aiming to enhance understanding of bibliometric data and complement existing endodontic knowledge. Nano-CT imaging has gained prominence in endodontics research, offering potential applications and insights into various aspects of the field. A review of relevant studies highlighted the technique's ability to visualize dentin tubules, root canal anatomy, filling quality, root resorption, cracks, microcracks, soft dental tissues, cellular layers, volumetric changes post-instrumentation, hard tissue debris, root surface deposits, and bioceramic pore structures. Nano-CT has the potential to become the gold standard for imaging in endodontics, presenting opportunities and challenges for future research. These findings provide researchers and practitioners with the latest advancements in nanoimaging.

纳米成像技术在牙髓学中发挥着至关重要的作用，它已经取得了进展，导致了更有效和更少侵入性的治疗。纳米计算机断层扫描（纳米ct）是一种先进的成像技术，用于评估骨结构或填充材料中的间隙，与传统设备相比，由于更小的焦点和体素，更高的信噪比，更高的管电压和功率，提供亚微米的空间分辨率，通过产生最小辐射暴露的详细图像来提高牙科成像精度和安全性。本研究对纳米ct成像作为牙髓学纳米识别工具进行了文献计量学分析。使用各种工具和方法，评估纳米ct的进展和趋势，旨在加强对文献计量数据的理解，并补充现有的牙髓学知识。纳米ct成像在牙髓学研究中获得了突出的地位，为该领域的各个方面提供了潜在的应用和见解。相关研究综述强调了该技术能够可视化牙本质小管、根管解剖、填充质量、根吸收、裂缝、微裂缝、软牙组织、细胞层、仪器后体积变化、硬组织碎片、根表面沉积物和生物陶瓷孔结构。纳米ct有可能成为牙髓学成像的黄金标准，为未来的研究带来机遇和挑战。这些发现为研究人员和从业人员提供了纳米成像的最新进展。

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引用次数: 0