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Aspects Regard of Quality and Quality Management in Road Transport 公路运输的质量和质量管理问题
Pub Date : 2024-05-17 DOI: 10.62225/2583049x.2024.4.3.2790
Gheorghe Neamțu
The scientific paper presents a concrete research carried out by the author in order to implement theoretical and practical concepts of a technical-managerial nature, in which aspects of quality and quality management in the field of road vehicle transport are presented. In this way those interested can learn about quality and quality management in the knowledge-based economy, described by increased competition with direct implications for the management of the road transport organisation. The following are aspects of quality and quality management in road transport in the context of market demands and the increasing complexity of the services provided. It also deals with issues related to how the activities and services of road transport organisations are certified in terms of quality and reviews the most important ISO standards used in the certification process of the quality of specific services. The principles and functions of knowledge-based quality management in road transport are defined. They are analysed from both an economic and a knowledge perspective. At the end of the paper it is shown how to implement Total Quality Management (TQM) in a road transport organisation and the conclusions in the field are drawn.
这篇科学论文介绍了作者为落实技术管理性质的理论和实践概念而开展的一项具体研究,其中介绍了道路车辆运输领域质量和质量管理的各个方面。通过这种方式,有兴趣的人可以了解知识经济时代的质量和质量管理,这种经济时代的特点是竞争加剧,对公路运输组织的管理有直接影响。以下是在市场需求和所提供服务日益复杂的背景下,公路运输质量和质量管理的各个方面。它还涉及如何对道路运输组织的活动和服务进行质量认证的相关问题,并回顾了在具体服务质量认证过程中使用的最重要的 ISO 标准。对公路运输中以知识为基础的质量管理的原则和功能进行了定义。本文从经济和知识两个角度对其进行了分析。文章最后介绍了如何在公路运输组织中实施全面质量管理 (TQM),并得出了该领域的结论。
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引用次数: 0
Analysis of the Effect of CEO Change and Financial Distress on Earnings Management in Insurance Companies Listed on the IDX for the 2013-2022 Period 2013-2022年IDX上市公司CEO变更和财务困境对盈利管理的影响分析
Pub Date : 2024-05-16 DOI: 10.62225/2583049x.2024.4.3.2785
Tirtha Melinda Suhartati, Widya Rizki Eka Putri
This research aims to provide a deeper understanding of the influence of CEO turnover and financial distress on earnings management practices in insurance companies. The study used insurance companies registered on the IDX for the 2013-2022 period as research objects, using a sample of 11 insurance companies that met the predetermined sample criteria and an observation period of 10 years. The observation data amounted to 110 data. The data collection method uses secondary data from the company's official website and the Indonesian Stock Exchange (BEI). The analytical method used in this research is multiple linear regression analysis using the SPSS (Statistical Product Service Solutions) version 27 application tool. Based on the results of data analysis and hypothesis testing, it shows that the CEO change variable does not affect earnings management. Meanwhile, financial distress affects earnings management.
本研究旨在深入了解首席执行官更替和财务困境对保险公司盈利管理实践的影响。研究以 2013-2022 年期间在 IDX 上注册的保险公司为研究对象,以符合预定样本标准的 11 家保险公司为样本,观察期为 10 年。观察数据共计 110 个。数据收集方法采用公司官方网站和印尼证券交易所(BEI)的二手数据。本研究采用的分析方法是使用 SPSS(统计产品服务解决方案)27 版应用工具进行多元线性回归分析。根据数据分析和假设检验的结果,CEO 变量不会影响收益管理。同时,财务困境会影响收益管理。
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引用次数: 0
Innovation meets Healthcare: MedVision 创新与医疗保健的结合:MedVision
Pub Date : 2024-05-16 DOI: 10.62225/2583049x.2024.4.3.2784
Alaik Asif Sheik, Mridul Mahajan, Smriti Sinha, Resmi Kr
This study describes MedVision, a pioneering healthcare and innovation platform to improve medical education. MedVision uses advanced technologies such as 3D modeling, augmented reality (AR) and smart tests to overcome the limitations of traditional medical education methods. In addition, a 3-D model is available to understand the subjects taught in class, while augmented reality views and a fairly advanced evaluation module are available for interactive teaching. For example, visitors can easily navigate the site with an easy-to-use chat that also helps them get to the information they need. Again, MedVision has a resource download module that aims to promote collaboration between doctors in sharing information. MedVision plans to revolutionize medical education by leveraging its innovative features that will ensure an era of engaging and effective medical training.
本研究介绍了 MedVision,一个旨在改善医学教育的开创性医疗保健和创新平台。MedVision 采用三维建模、增强现实(AR)和智能测试等先进技术,克服了传统医学教育方法的局限性。此外,还可通过三维模型了解课堂教学科目,而增强现实视图和相当先进的评估模块则可用于互动教学。例如,访客可以通过简单易用的聊天工具轻松浏览网站,聊天工具还可以帮助访客获取所需的信息。同样,MedVision 还有一个资源下载模块,旨在促进医生之间在共享信息方面的合作。MedVision 计划利用其创新功能彻底改变医学教育,以确保一个引人入胜和有效的医学培训时代的到来。
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引用次数: 0
Survey Study of the Importance of Cultural Diplomacy of Indonesia in Azerbaijan 关于印度尼西亚在阿塞拜疆文化外交重要性的调查研究
Pub Date : 2024-05-11 DOI: 10.62225/2583049x.2024.4.3.2777
Brilliant Windy Khairunnisa
Since the existence of the Embassy of the Republic of Indonesia in Azerbaijan, Indonesia began to strengthen its relations with Azerbaijan massively through cultural diplomacy through performances as well as cultural events. Furthermore, the cultural diplomacy of Indonesia and Azerbaijan is also conducted through cultural scholarship, the study of the Indonesian language, as well as learning its dances in the embassy for Azeri students. This study aims to describe the importance of Indonesia's cultural diplomacy in Azerbaijan by employing a descriptive quantitative research method in which the data is obtained through the primary survey conducted by the author. The study found that utilising culture in Indonesia’s diplomatic practices in Azerbaijan is a paramount thing to building a strong bond and trust between countries, especially at the young age of the embassy existence in Azerbaijan.
自印度尼西亚共和国驻阿塞拜疆大使馆成立以来,印度尼西亚开始通过演出和文化活动开展文化外交,大力加强与阿塞拜疆的关系。此外,印尼和阿塞拜疆的文化外交还通过文化奖学金、印尼语学习以及阿塞拜疆学生在大使馆学习印尼舞蹈等方式进行。本研究采用描述性定量研究方法,通过作者进行的初步调查获取数据,旨在描述印尼在阿塞拜疆开展文化外交的重要性。研究发现,在印尼驻阿塞拜疆的外交实践中利用文化是在国家间建立牢固纽带和信任的首要条件,尤其是在驻阿塞拜疆使馆成立之初。
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引用次数: 0
Dermatological Manifestations of COVID-19 Patients COVID-19 患者的皮肤病表现
Pub Date : 2024-05-09 DOI: 10.62225/2583049x.2024.4.3.2762
L. Khondker, Md Shirajul Islam Khan, Abu Reza Sayem Ahamed
Background: COVID-19 is a highly contagious respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), was first identified in China, in December 2019. Almost 10% of the patients develop dermatological manifestations before the onset of respiratory illness, with cutaneous signs that can appear from before to several days after the diagnosis of COVID-19. We believe that the dermatologist can play an important role through early recognition of skin lesions suggestive of COVID-19, particularly in asymptomatic infections where this recognition could direct toward an early diagnosis of infection that certainly leads to a better prognosis. Objective: To explore the pattern of dermatological manifestations among COVID-19 Bangladeshi patients. Materials and Methods: A cross sectional study was carried out May 2020 to October 2021 with COVID 19 positive hospital admitted patients. Data were collected through a group of Dermatologists who were serving at COVID dedicated Hospitals. Dermatologists, who were working in different medical college hospital and health complexes, were attached with the study as research associate. Results: Among the muco-cutaneous findings, maculo-papular eruption 52(53.6%) was the most common, followed by chilblain like eruption 40(41.2%), petechiae or purpura 16 (16.5%), urticarial lesions 13(13.4%), vesicular lesion 10(10.3%), Bilateral conjunctivitis with clear/mucoid discharge 10 (10.3%), aphthous stomatitis 13 (13.4%), Alopecia 16(16.5%), Darkening of the face 13 (13.4%), Eczematoid reaction 13 (13.4%), livedo reticularis like eruption 5(5.2%) etc. Conclusion: The major dermatological patterns of COVID-19 can be classified as inflammatory reactions (maculopapular, urticarial and vesicular rashes), or lesions of vascular origin (chilblain like rashes, petechiae/purpura, and livedo reticularis like pattern).
背景:COVID-19是由严重急性呼吸系统综合征冠状病毒2(SARS-CoV-2)引起的高度传染性呼吸道传染病,于2019年12月在中国首次发现。近10%的患者在呼吸道发病前出现皮肤病表现,皮肤症状可在COVID-19确诊前至确诊后数天出现。我们认为,皮肤科医生可以通过早期识别提示 COVID-19 的皮肤病变发挥重要作用,尤其是在无症状感染的情况下,这种识别可以指导感染的早期诊断,从而获得更好的预后。目的探讨 COVID-19 孟加拉患者的皮肤病表现模式。材料与方法:2020 年 5 月至 2021 年 10 月,对 COVID 19 阳性住院患者进行了横断面研究。数据通过一组在 COVID 专属医院工作的皮肤科医生收集。在不同医学院附属医院和综合保健中心工作的皮肤科医生也作为研究助理参与了这项研究。研究结果在皮肤粘液检查结果中,最常见的是斑丘疹 52(53.6%),其次是皲裂样疹子 40(41.2%)、瘀斑或紫癜 16(16.5%)、荨麻疹 13(13.4%)、水泡 10(10.3%)、双侧结膜 10(10.3%)、溃疡 13(13.4%)。3%)、双侧结膜炎伴透明/粘液性分泌物 10(10.3%)、阿弗他口腔炎 13(13.4%)、脱发 16(16.5%)、面部变黑 13(13.4%)、类湿疹反应 13(13.4%)、活网状皮疹 5(5.2%)等。结论COVID-19 的主要皮肤病型可分为炎症反应(斑丘疹、荨麻疹和水泡性皮疹)或血管性病变(鸡皮样皮疹、瘀斑/脓疱疮和类活网状皮疹)。
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引用次数: 0
Status and Inheritance Rights of Daha Tua in Balinese Customary Inheritance Law: Study on Balinese Indigenous People in Banjar Dewa Village, Banjar Agung District, Tulang Bawang Regency Daha Tua 在巴厘岛习惯继承法中的地位和继承权:巴厘岛原住民研究:Tulang Bawang 县 Banjar Agung 区 Banjar Dewa 村的巴厘岛原住民
Pub Date : 2024-05-09 DOI: 10.62225/2583049x.2024.4.3.2761
Ni Luh Nita Sari, I. G. AB Wiranata, Kasmawati, Aprilianti, Dewi Septiana
Old Daha is an adult woman biologically menstruating, until old age. It is said that Daha Tua if his status does not carry out marriage until the end of reproductive ability. So Old Daha was an adult woman until she died with the status of never married. The situation of Old Daha will be set aside by his family members because it is considered a mere burden, so the issue of Old Daha's inheritance rights arises and the distribution of Old Daha's inheritance rights to his heirs in Banjar Dewa Village, Banjar Agung District, Tulang Bawang Regency. This research is empirical normative legal research, with a descriptive type. The problem approach used is a juridical-sociological approach. The data used are secondary data and primary data. Data collection techniques with literature studies and field studies are interviews. Data analysis is used qualitative data analysis. The results showed that Daha Tua in Banjar Dewa Village was not an heir, however, along with the development of the era, parents assumed that Daha Tua was entitled to receive his parents' property while still paying attention to customary law as a guideline that applies in the Balinese customary inheritance system. The distribution of inheritance rights belonging to Daha Tua to his heirs in Banjar Dewa Village will be inherited to heirs who are related to Purusa by blood, such as his chosen brother or by adopting the nephew of his brother as a legitimate child. These efforts were made to get heirs and shelter in old age.
老达哈是指生理上有月经的成年妇女,直到老年。据说 Daha Tua 如果有身份就不会结婚,直到生殖能力结束。因此,老达哈是一名成年妇女,直到她去世时都没有结婚。老达哈的情况将被其家庭成员搁置一旁,因为他们认为这只是一种负担,因此出现了老达哈的继承权问题,以及如何将老达哈的继承权分配给其继承人的问题。本研究属于实证规范法律研究,属于描述型研究。采用的问题方法是法学-社会学方法。使用的数据包括二手数据和一手数据。文献研究和实地研究的数据收集技术是访谈。数据分析采用定性数据分析。研究结果表明,Banjar Dewa 村的 Daha Tua 不是继承人,但是,随着时代的发展,父母认为 Daha Tua 有权继承父母的财产,同时仍将习惯法作为适用于巴厘岛习惯继承制度的准则。在 Banjar Dewa 村,属于 Daha Tua 的继承权将分配给与 Purusa 有血缘关系的继承人,如他选择的兄弟或收养其兄弟的侄子为婚生子女。这些努力都是为了得到继承人和晚年的庇护。
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引用次数: 0
Effects of Mebyakaonan Marriage Law in the Perspective of Balinese Customary Law: Study on Balinese Community, Rantau Jaya Village, Ilir District, Putra Rumbia, Central Lampung Regency 从巴厘习惯法的角度看 Mebyakaonan 婚姻法的影响:楠榜中部 Putra Rumbia 的 Ilir 区 Rantau Jaya 村巴厘人社区研究
Pub Date : 2024-05-09 DOI: 10.62225/2583049x.2024.4.3.2760
Dewa Ayu Putu Widia Asih, I. G. AB Wiranata, Kasmawati, Aprilianti, Dewi Septiana
Marriage is the outward and inner bond between a man and a woman as husband and wife to continue their lineage. Marriage in Balinese customs is called pawiwahan. Pawiwahan is a sacred thing in the process of human life from the status of brahmacari to the time of grhasta. Mebyakaon marriage is marriage under the hand. The problem in this study is why mebyakaon marriage is taken by the parties to form a marriage and the legal consequences of mebyakaon marriage on their marital status in the community and the status of children born from this marriage in Rantau Jaya Ilir Village, Putra Rumbia District, Central Lampung Regency. This research is normative-empirical legal research with a descriptive research type. The problem approach used sociological juridical approach with data sources is primary data and secondary data. Data collection techniques with literature studies and field studies are interviews with informants and respondents who carry out marriage mebyakaon. Data analysis is qualitative analysis. The results of research and discussion show that the reason for the marriage is caused by several factors, namely economic factors, educational factors, mutual demen, parental desire factors, and the factor of men who are still legally married to other women. The marital status of mebyakaon is not the same as traditional Balinese marriage in general, what distinguishes it from mebyakaon marriage is that it lies in a traditional procession that has not been carried out completely. Based on the decisions and decrees of Parisadha Hindu Dharma Indonesia (PHDI), the validity of marriage is determined on condition that Tri Upasaksi. The legal position of mebyakaon marriage does not have a strong binding force so that this marriage may not have the same legal status as traditional Balinese married couples in general. Similarly, the legal consequences of marriage will be different. Couples who perform mebyakaon marriage may not enter the temple and participate in the massacre in the village because mebyakaon marriage is valid according to the parties only but, according to Balinese customary law this marriage is invalid and children born from mebyakaon marriage are extramarital children (anak astra) and marital property in mebyakaon marriage There is no legal certainty and there is no mixing of property between husband and wife.
婚姻是男女之间作为夫妻延续血脉的外在和内在纽带。在巴厘岛的习俗中,婚姻被称为 "pawiwahan"。从梵天(brahmacari)到格哈斯塔(ghasta),帕维瓦罕(pawiwahan)是人类生命过程中一件神圣的事情。Mebyakaon 婚姻是指牵手婚姻。本研究的问题是:在楠榜中央省 Putra Rumbia 区 Rantau Jaya Ilir 村,为什么双方会以 "mebyakaon 婚姻 "缔结婚姻,以及 "mebyakaon 婚姻 "对他们在社区中的婚姻状况和由此婚姻所生子女的地位产生的法律后果。本研究属于规范-实证法律研究,属于描述性研究类型。解决问题的方法采用社会学司法方法,数据来源为一手数据和二手数据。数据收集技术包括文献研究和实地研究,包括对信息提供者和进行婚姻mebyakaon的受访者进行访谈。数据分析为定性分析。研究和讨论的结果表明,婚姻的原因是由几个因素造成的,即经济因素、教育因素、互惠因素、父母的愿望因素以及仍与其他妇女合法结婚的男子的因素。mebyakaon的婚姻状况与巴厘岛传统婚姻的一般状况不同,它与mebyakaon婚姻的区别在于传统的结婚程序尚未完全结束。根据印度尼西亚帕里斯达印度教法(Parisadha Hindu Dharma Indonesia,PHDI)的决定和法令,婚姻的有效性取决于 Tri Upasaksi 的条件。mebyakaon婚姻的法律地位不具有很强的约束力,因此这种婚姻可能不具有与传统巴厘岛已婚夫妇一般的法律地位。同样,婚姻的法律后果也会有所不同。举行 "mebyakaon 婚 "的夫妇不能进入寺庙,也不能参加村里的屠杀,因为 "mebyakaon 婚 "只对当事人有效,但根据巴厘岛习惯法,这种婚姻是无效的,"mebyakaon 婚 "所生子女属于婚外子女(anak astra),"mebyakaon 婚 "中的夫妻财产没有法律确定性,夫妻财产也不混合。
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引用次数: 0
Role of Dutasteride in the Treatment of Androgenetic Alopecia 度他雄胺在治疗雄激素性脱发中的作用
Pub Date : 2024-05-09 DOI: 10.62225/2583049x.2024.4.3.2763
L. Khondker, Pranam Swapan Dash
This study evaluates the role of dutasteride in the treatment of androgenetic alopecia. A prospective, open-labeled interventional study conducted at the Department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from April 2023 to March 2024. Men with Androgenetic alopecia (AGA) who did not show significant improvement when treated with finasteride at a dose of 1 mg/d for at least six months were enrolled. Ninety patients were recruited after taking informed consent. Patients were treated with dutasteride at a dose of 0.5 mg daily for 24 weeks. Clinical assessment was performed by dermatologists and subjective evaluation of overall assessment was done based onchanges in the size of the vertex spot, hair loss on top of the scalp, bitemporal recession, the amount of hair shedding and hair quality on a 3-point rating scale (increased, no change, or decreased). The mean age of study patients was 36.3±12 years and majority of the patients 30(33.3%) belonged to the age group 41- 50 years with followed by 27(30.0%) in the age group 31-40 years. Regarding subjective evaluation of overall assessment, in case of change in size of vertex spot, majority 77(85.6%) showed decreased, in case of hair loss from top of scalp, majority 83(92.2%) reported decreased, in case of bitemporal recession, majority 82(91.1%) showedno change, in case of hair shedding, majority 87(96.7%) showed decreased and in case of hair quality, 85(94.4%) reported increased and no patient reported of decreased. Regarding clinical assessment of investigator that majority of the patients 40(44.5%) was moderately improved (+2), followed by 30(33.3%) was greatly improved (score of +3), 18(20.0%) was slightly improved (+1) and only 2(2.2%) was unchanged (0). Among the ninety patients of androgenetic alopecia, 3(3.3%) showed decreased libido and 2(2.2%) showed erectile dysfunction. The study concluded that dutasteride is effective and safe in the treatment of androgenetic alopecia. This study will provide the therapeutic basis for dutasteride as an alternative treatment option for patients with AGA recalcitrant to finasteride over six months. Therefore, dutasteride will become a treatment of choice for androgenetic alopecia (AGA) in near future.
本研究评估了度他雄胺在治疗雄激素性脱发中的作用。这是一项前瞻性、开放标签的干预研究,于 2023 年 4 月至 2024 年 3 月在达卡班加班杜谢赫-穆吉布医科大学(BSMMU)皮肤病与性病学系进行。该研究招募了雄激素性脱发(AGA)男性患者,这些患者在接受非那雄胺治疗至少六个月(剂量为 1 毫克/天)后,病情没有明显改善。在获得知情同意后,共招募了 90 名患者。患者接受每日0.5毫克剂量的度他雄胺治疗,为期24周。由皮肤科医生进行临床评估,并根据顶点大小、头皮顶部脱发情况、颞部脱发情况、头发脱落量和头发质量的变化(增加、无变化或减少)进行主观评估。研究对象的平均年龄为(36.3±12)岁,其中 30 人(33.3%)属于 41-50 岁年龄组,27 人(30.0%)属于 31-40 岁年龄组。在对总体评估的主观评价方面,在顶点大小变化方面,大多数 77 人(85.6%)表示有所减少;在头皮顶部脱发方面,大多数 83 人(92.2%)表示有所减少;在颞部脱发方面,大多数 82 人(91.1%)表示没有变化;在头发脱落方面,大多数 87 人(96.7%)表示有所减少;在头发质量方面,85 人(94.4%)表示有所增加,没有患者表示有所减少。根据研究人员的临床评估,大多数患者有 40 人(44.5%)病情得到中度改善(+2 分),30 人(33.3%)病情得到大幅改善(+3 分),18 人(20.0%)病情得到轻微改善(+1 分),只有 2 人(2.2%)病情不变(0 分)。在 90 名雄激素性脱发患者中,3 人(3.3%)性欲减退,2 人(2.2%)出现勃起功能障碍。研究认为,度他雄胺治疗雄激素性脱发有效且安全。这项研究将为使用非那雄胺超过 6 个月仍不见效的 AGA 患者提供治疗依据,将其作为一种替代疗法。因此,在不久的将来,度他雄胺将成为治疗雄激素性脱发(AGA)的首选药物。
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引用次数: 0
An Observational Study on Perception of Efficacy of Crop Insurance among the Farmers of a Community Development Block in the State of West Bengal 关于西孟加拉邦社区发展区块农民对农作物保险有效性认识的观察研究
Pub Date : 2024-05-09 DOI: 10.62225/2583049x.2024.4.3.2767
Sumita Saha
Crop insurance is a formal mechanism of risk management to farmers exposed to a similar type of risk in agricultural production. It is a means to protect the cultivators against financial loss on account of anticipated crop loss which might arise out of uncontrollable natural calamities such as natural fire, weather, floods, pests, diseases etc. In West Bengal, various crop insurance schemes have been implemented so far. The common aim of the schemes is to provide financial support to farmers in the event of crop failure and stabilize farm production and income of the farming community. This is the motivation behind the study. The study has been conducted among farmers of Hooghly district in West Bengal to understand their perception of efficacy of crop insurance schemes. Respondents include both insured and non-insured farmers. The mean age of the farmers with crop insurance was 43.18±16.13 years and the mean age of the ones without crop insurance was 44.22±18.07 years respectively (p=0.62). All respondents were males with full ownership of farms. The mean size of the farms was 5.95±3.28 bigha. A total number of 60 farmers were selected randomly out of which 30 farmers were with crop insurance and rest 30 were without crop insurance. Among the risk management strategies adopted for the destruction of crops, sale/ mortgage of land, sale of livestock and government relief were higher among non-insured farmers as compared to insured farmers (p>0.05).
农作物保险是对面临类似农业生产风险的农民进行风险管理的正式机制。它是一种保护耕种者的手段,使其免受因无法控制的自然灾害(如自然火灾、天气、洪水、病虫害等)可能造成的预期作物损失而带来的经济损失。迄今为止,西孟加拉邦已实施了各种农作物保险计划。这些计划的共同目标是在农作物歉收时为农民提供财政支持,稳定农业生产和农民收入。这也是本研究的动机所在。本研究在西孟加拉邦 Hooghly 地区的农民中开展,以了解他们对农作物保险计划功效的看法。受访者包括投保和未投保的农民。投保农作物保险的农民的平均年龄为(43.18±16.13)岁,未投保农作物保险的农民的平均年龄为(44.22±18.07)岁(P=0.62)。所有受访者均为男性,拥有全部农场所有权。农场的平均面积为(5.95±3.28)公顷。随机抽取了 60 位农民,其中 30 位农民购买了农作物保险,其余 30 位农民没有购买农作物保险。与投保农户相比,未投保农户在农作物毁坏时采取的风险管理策略中,出售/抵押土地、出售牲畜和政府救济的比例较高(P>0.05)。
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引用次数: 0
Effect of Base Type Variation on Physicochemical Properties of Ambon Banana Peel (Musa Paradisiaca L) Methanol Extract Nanoemulsions Ointment 碱类型变化对安汶香蕉皮(Musa Paradisiaca L)甲醇提取物纳米乳软膏理化性质的影响
Pub Date : 2024-05-08 DOI: 10.62225/2583049x.2024.4.3.2757
Ulfa Afrinurfadhilah D, Rahma Nur Fitriana
Ambon banana peel (Musa Paradisiaca L) contains flavonoids, tannins, terpenoids and saponins which have potential to be in the wound healing process. One of topical preparations suitable for wound healing is ointment. The ointment base can affect the release of active substances and absorption in the skin layers, since the release of the drug from its base is an important factor in the success of therapy. The aim of this study was to analyze the effect of base type variations on the physicochemical properties of ointments from banana peel methanol extract nanoemulsions. Ambon banana peel extract was obtained by maceration using methanol solvent and made in the form of a nanoemulsion. Ambon banana peel extract nanoemulsion is then added to the ointment preparation with water-soluble, absorption and hydrocarbon base types. Ointments with variations in base types were observed for physicochemical properties including organoleptic, homogeneity, viscosity, pH and spreadability. The data obtained were analyzed statistically using One Way ANOVA. The results showed that variations in base type affected on organoleptic appearance, viscosity and spreadability but had no effect on the pH value and homogeneity. The absorption base produces a formula that meets the requirements for ointment preparations.
安汶香蕉皮(Musa Paradisiaca L)含有黄酮类、单宁、萜类和皂苷,这些物质在伤口愈合过程中具有潜在作用。适合伤口愈合的外用制剂之一是软膏。软膏基质会影响活性物质的释放和皮肤层的吸收,因为药物从基质中的释放是治疗成功与否的重要因素。本研究旨在分析基质类型变化对香蕉皮甲醇提取物纳米乳软膏理化性质的影响。安邦香蕉皮提取物是用甲醇溶剂浸泡后制成纳米乳液的。然后将安汶香蕉皮提取物纳米乳液添加到水溶性、吸收性和碳氢化合物基质类型的软膏制剂中。对不同基质类型的软膏进行理化性质观察,包括感官、均匀性、粘度、pH 值和涂抹性。所得数据采用单向方差分析法进行统计分析。结果表明,基质类型的变化会影响感官外观、粘度和涂抹性,但对 pH 值和均一性没有影响。吸收型基质所产生的配方符合软膏制剂的要求。
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引用次数: 0
期刊
International Journal of Advanced Multidisciplinary Research and Studies
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