Pub Date : 2024-07-03DOI: 10.24843/mu.2024.v13.i07.p09
Dewa Ayu Agung Alit Suka Astini, Luh Gde Evayanti, Ni Putu Diah Witari, K. T. Sumadewi, A.A.A Asri Prima Dewi, Fransiscus Fiano Anthony Kerans, Ida Kurniawati
Noise is defined as unwanted and disruptive sound, considered an environmental stressor and disturbance. Noise encompasses many aspects of modern communities, including work environments. The damaging effects of noise primarily result from the unrestricted production of free radicals into the auditory organs. Exposure to noise causes various health problems, such as hearing impairment, sleep disturbances, and interference with individual performance. Reactive oxygen species (ROS), also known as free oxygen radicals, are normal by-products of cellular aerobic metabolism. These unstable molecules can damage cellular lipids, proteins, and nucleic acids in DNA if the antioxidant balance is disrupted. Acute and chronic exposure to loud noise generates excessive free radicals and disrupts extra-auditory organs such as the nervous, endocrine, and cardiovascular systems. The purpose of this study is to analyze the relationship between noise exposure and the number of neurons in the temporal lobes of Wistar rats. The research design used is a laboratory experimental design, specifically a pure experimental design, implemented with the randomized posttest-only control group design. The research sample consists of 30 male Wistar rats randomized into 2 groups, control and treatment. The treatment group is exposed to 95dB noise for 4 hours per day for 14 days. The rats are then euthanized, and their brain tissue is fixed with 10% neutral buffered formalin. Assessment is performed using Hematoxylin Eosin staining, and analysis is conducted blindly on the average number of neurons in the rat's temporal lobes. Data is subjected to normality testing using the Shapiro-Wilk test and analyzed using independent t-tests for parametric comparison. The results show a significant difference in the mean number of neurons in the temporal lobes between rats exposed to noise and the control group (p <0.005). The conclusion of this study is that noise affects neuron cells in the temporal lobes. Keywords : noise, temporal lobe, neurons.
{"title":"THE EFFECT OF NOISE EXPOSURE ON THE AVERAGE NUMBER OF TEMPORAL LOBUS NEURONS IN ADULT WISTAR RATS","authors":"Dewa Ayu Agung Alit Suka Astini, Luh Gde Evayanti, Ni Putu Diah Witari, K. T. Sumadewi, A.A.A Asri Prima Dewi, Fransiscus Fiano Anthony Kerans, Ida Kurniawati","doi":"10.24843/mu.2024.v13.i07.p09","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p09","url":null,"abstract":"Noise is defined as unwanted and disruptive sound, considered an environmental stressor and disturbance. Noise encompasses many aspects of modern communities, including work environments. The damaging effects of noise primarily result from the unrestricted production of free radicals into the auditory organs. Exposure to noise causes various health problems, such as hearing impairment, sleep disturbances, and interference with individual performance. Reactive oxygen species (ROS), also known as free oxygen radicals, are normal by-products of cellular aerobic metabolism. These unstable molecules can damage cellular lipids, proteins, and nucleic acids in DNA if the antioxidant balance is disrupted. Acute and chronic exposure to loud noise generates excessive free radicals and disrupts extra-auditory organs such as the nervous, endocrine, and cardiovascular systems. The purpose of this study is to analyze the relationship between noise exposure and the number of neurons in the temporal lobes of Wistar rats. The research design used is a laboratory experimental design, specifically a pure experimental design, implemented with the randomized posttest-only control group design. The research sample consists of 30 male Wistar rats randomized into 2 groups, control and treatment. The treatment group is exposed to 95dB noise for 4 hours per day for 14 days. The rats are then euthanized, and their brain tissue is fixed with 10% neutral buffered formalin. Assessment is performed using Hematoxylin Eosin staining, and analysis is conducted blindly on the average number of neurons in the rat's temporal lobes. Data is subjected to normality testing using the Shapiro-Wilk test and analyzed using independent t-tests for parametric comparison. The results show a significant difference in the mean number of neurons in the temporal lobes between rats exposed to noise and the control group (p <0.005). The conclusion of this study is that noise affects neuron cells in the temporal lobes. \u0000Keywords : noise, temporal lobe, neurons.","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"58 S274","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.24843/mu.2024.v13.i07.p06
Nadya Zalfa Aqilah, Ni Gusti, Ayu Agung, Manik Yuniawaty, Wetan, I. Gede, Budhi Setiawan, Putu Anda, Tusta Adiputra
Breast cancer is a disease that has high mortality in women throughout the world. Breast cancer has characteristics and risk factors that influence the incidence of breast cancer. The research method uses a retrospective descriptive study and uses secondary data, namely medical records at the Central General Hospital Prof. Dr. I G.N.G. Ngoerah in 2022. Of the total 551 samples, only 319 samples had complete medical records. The variables studied were age, clinical stage, histopathological type, biopsy grade, subtype, lesion location, menopausal status, age at menarche, age at menopause, family history of cancer, parity, breastfeeding history, history of hormonal therapy, and nutritional status in terms of BMI. The results showed that of the 319 breast cancer patients, 77.4% were ?45 years old, 38.2% were stage IIIB, 86.2% were invasive ductal carcinoma, 56.4% were grade III, 36.4% were luminal B subtype, 41.4% were in the menopausal phase, the average age of menarche was 13 years old, 42% had menopause in the 45-50 year age range, 4.4% had a family history of cancer, 73% were multiparous, 91.5% had a history of breastfeeding, 23.8% had a history of hormonal therapy, and 37.3% had a normal BMI nutritional status. Keywords: Characteristics, Risk Factors, Breast Cancer
乳腺癌是全世界妇女死亡率较高的一种疾病。乳腺癌的特点和风险因素影响着乳腺癌的发病率。研究方法采用回顾性描述研究，并使用二级数据，即 2022 年 I G.N.G. Ngoerah 教授中央综合医院的医疗记录。在总共 551 个样本中，只有 319 个样本有完整的医疗记录。研究的变量包括年龄、临床分期、组织病理学类型、活检分级、亚型、病变位置、绝经状态、初潮年龄、绝经年龄、癌症家族史、胎次、哺乳史、激素治疗史以及以体重指数（BMI）表示的营养状况。结果显示，在 319 名乳腺癌患者中，77.4% 年龄在 45 岁以下，38.2% 为 IIIB 期，86.2% 为浸润性导管癌，56.4% 为 III 级，36.4% 为管腔 B 亚型，41.4%的患者处于绝经期，平均初潮年龄为13岁，42%的患者绝经年龄在45-50岁之间，4.4%的患者有癌症家族史，73%的患者为多胎妊娠，91.5%的患者有哺乳史，23.8%的患者有激素治疗史，37.3%的患者BMI营养状况正常。关键词特征 风险因素 乳腺癌
{"title":"Characteristics and Risk Factors of Breast Cancer at The Central General Hospital Prof. DR. I G.N.G. Ngoerah in 2022","authors":"Nadya Zalfa Aqilah, Ni Gusti, Ayu Agung, Manik Yuniawaty, Wetan, I. Gede, Budhi Setiawan, Putu Anda, Tusta Adiputra","doi":"10.24843/mu.2024.v13.i07.p06","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p06","url":null,"abstract":"Breast cancer is a disease that has high mortality in women throughout the world. Breast cancer has characteristics and risk factors that influence the incidence of breast cancer. The research method uses a retrospective descriptive study and uses secondary data, namely medical records at the Central General Hospital Prof. Dr. I G.N.G. Ngoerah in 2022. Of the total 551 samples, only 319 samples had complete medical records. The variables studied were age, clinical stage, histopathological type, biopsy grade, subtype, lesion location, menopausal status, age at menarche, age at menopause, family history of cancer, parity, breastfeeding history, history of hormonal therapy, and nutritional status in terms of BMI. The results showed that of the 319 breast cancer patients, 77.4% were ?45 years old, 38.2% were stage IIIB, 86.2% were invasive ductal carcinoma, 56.4% were grade III, 36.4% were luminal B subtype, 41.4% were in the menopausal phase, the average age of menarche was 13 years old, 42% had menopause in the 45-50 year age range, 4.4% had a family history of cancer, 73% were multiparous, 91.5% had a history of breastfeeding, 23.8% had a history of hormonal therapy, and 37.3% had a normal BMI nutritional status. \u0000Keywords: Characteristics, Risk Factors, Breast Cancer","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141684156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.24843/mu.2024.v13.i07.p07
I. Made, Agus Setiawan, Luh Dewi, Jurnal Medika Udayana
Karsinoma tiroid merupakan kanker endokrin pada kelenjar tiroid dengan jumlah kasus yang tinggi di Indonesia. Beberapa penelitian menemukan bahwa usia dan jenis kelamin memengaruhi prognosis dari karsinoma tiroid. Penelitian ini bertujuan untuk mengetahui hubungan antara usia dan jenis kelamin terhadap tipe histopatologi karsinoma tiroid. Dalam penelitian ini sampel diambil dari hasil pemeriksaan histopatologi dengan diagnosis karsinoma tiroid yang dilakukan di Laboratorium Patologi Anatomi Rumah Sakit Daerah Mangusada sejak 1 Januari 2022 hingga 31 Desember 2023. Uji statistik digunakan untuk menilai hubungan antara usia dan jenis kelamin terhadap tipe histopatologi karsinoma tiroid. Terdapat 33 pasien dengan diagnosis karsinoma tiroid di RSD Mangusada sejak tahun 2022 – 2023 dengan jumlah tertinggi terjadi pada usia 40 – 49 tahun sebanyak 12 pasien (36,4%). Kasus didominasi oleh perempuan sebanyak 27 pasien (81,8%) dengan rasio laki – laki dan perempuan 1:4,5. Papillary thyroid carcinoma merupakan tipe terbanyak yaitu 32 pasien (97%) diikuti dengan follicular thyroid carcinoma sebanyak 1 pasien (3%). Baik usia dan jenis kelamin tidak menunjukkan hubungan yang signifikan terhadap tipe histopatologi karsinoma tiroid (p > 0,05). Kata Kunci: usia, jenis kelamin, tipe histopatologi karsinoma tiroid
{"title":"RELATIONSHIP BETWEEN AGE AND GENDER WITH THE HISTOPATHOLOGICAL TYPE OF THYROID CARCINOMA IN MANGUSADA HOSPITAL","authors":"I. Made, Agus Setiawan, Luh Dewi, Jurnal Medika Udayana","doi":"10.24843/mu.2024.v13.i07.p07","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p07","url":null,"abstract":"Karsinoma tiroid merupakan kanker endokrin pada kelenjar tiroid dengan jumlah kasus yang tinggi di Indonesia. Beberapa penelitian menemukan bahwa usia dan jenis kelamin memengaruhi prognosis dari karsinoma tiroid. Penelitian ini bertujuan untuk mengetahui hubungan antara usia dan jenis kelamin terhadap tipe histopatologi karsinoma tiroid. Dalam penelitian ini sampel diambil dari hasil pemeriksaan histopatologi dengan diagnosis karsinoma tiroid yang dilakukan di Laboratorium Patologi Anatomi Rumah Sakit Daerah Mangusada sejak 1 Januari 2022 hingga 31 Desember 2023. Uji statistik digunakan untuk menilai hubungan antara usia dan jenis kelamin terhadap tipe histopatologi karsinoma tiroid. Terdapat 33 pasien dengan diagnosis karsinoma tiroid di RSD Mangusada sejak tahun 2022 – 2023 dengan jumlah tertinggi terjadi pada usia 40 – 49 tahun sebanyak 12 pasien (36,4%). Kasus didominasi oleh perempuan sebanyak 27 pasien (81,8%) dengan rasio laki – laki dan perempuan 1:4,5. Papillary thyroid carcinoma merupakan tipe terbanyak yaitu 32 pasien (97%) diikuti dengan follicular thyroid carcinoma sebanyak 1 pasien (3%). Baik usia dan jenis kelamin tidak menunjukkan hubungan yang signifikan terhadap tipe histopatologi karsinoma tiroid (p > 0,05). \u0000 \u0000Kata Kunci: usia, jenis kelamin, tipe histopatologi karsinoma tiroid","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.24843/mu.2024.v13.i07.p03
Kadek Khrisna Fernanda Erawan, Pande Putu Ayu Patria Dewi, Desak Gde Diah Dharma Santhi, Ni Kadek Mulyantari
Typhoid fever is systemic infection which is caused by Salmonella typhi. The gold standard of typhoid fever diagnosis is blood culture examination. Blood culture examination has a weakness, it could not be practically performed especially due to lack of laboratory facility. There are several others alternative examination including serology and hematology examination that could be used in supporting typhoid fever diagnosis. Therefore, investigation of hematology and serology examination results of typhoid fever patient is required. The type of research carried out was descriptive research with a cross-sectional design using secondary data from medical records of typhoid fever patients at Prof. Ngoerah General Hospital. A total of 52 patients with a diagnosis of typhoid fever as research subjects were taken using a total sampling technique. Following data were obtained: age, gender, serology and hematology examination result, type of antibiotics given, and complications found. Data processing was carried out using the SPSS ver. 26 with univariate analysis. This study found that typhoid fever patient at Prof. Ngoerah General Hospital tend to have normal hematological examination result including hemoglobin level, total count of leukocyte (neutrophile and lymphocyte) and thrombocyte. Widal test result of the patients showed the lowest titer value is 1/80 and the highest is 1/320 at O and H titers. Most of the patients have positive IgM anti-Salmonella typhi score of 4 and 6. 3 patients (5.8%) have negative IgM score of 2 and 11 patients (21.2%) did not have an IgM test. Most of the patients acquired antibiotic treatment with ceftriaxone become most used antibiotic. Complication is rarely occurred among the patients. Hepatomegaly is the most frequent complication occurred among the patients with complication.
{"title":"LABORATORY EXAMINATION OF TYPHOID FEVER PATIENT AT PROF. NGOERAH GENERAL HOSPITAL IN 2020-2022","authors":"Kadek Khrisna Fernanda Erawan, Pande Putu Ayu Patria Dewi, Desak Gde Diah Dharma Santhi, Ni Kadek Mulyantari","doi":"10.24843/mu.2024.v13.i07.p03","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p03","url":null,"abstract":"Typhoid fever is systemic infection which is caused by Salmonella typhi. The gold standard of typhoid fever diagnosis is blood culture examination. Blood culture examination has a weakness, it could not be practically performed especially due to lack of laboratory facility. There are several others alternative examination including serology and hematology examination that could be used in supporting typhoid fever diagnosis. Therefore, investigation of hematology and serology examination results of typhoid fever patient is required. The type of research carried out was descriptive research with a cross-sectional design using secondary data from medical records of typhoid fever patients at Prof. Ngoerah General Hospital. A total of 52 patients with a diagnosis of typhoid fever as research subjects were taken using a total sampling technique. Following data were obtained: age, gender, serology and hematology examination result, type of antibiotics given, and complications found. Data processing was carried out using the SPSS ver. 26 with univariate analysis. This study found that typhoid fever patient at Prof. Ngoerah General Hospital tend to have normal hematological examination result including hemoglobin level, total count of leukocyte (neutrophile and lymphocyte) and thrombocyte. Widal test result of the patients showed the lowest titer value is 1/80 and the highest is 1/320 at O and H titers. Most of the patients have positive IgM anti-Salmonella typhi score of 4 and 6. 3 patients (5.8%) have negative IgM score of 2 and 11 patients (21.2%) did not have an IgM test. Most of the patients acquired antibiotic treatment with ceftriaxone become most used antibiotic. Complication is rarely occurred among the patients. Hepatomegaly is the most frequent complication occurred among the patients with complication.","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"24 s4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breast cancer is the uncontrolled growth of cells or tissue in the breast. Chemotherapy is the first therapeutic choice for treating cancer. One of the symptoms felt by breast cancer patients undergoing chemotherapy is a decrease in sleep quality. Sleep quality is a person's sense of satisfaction with their sleep. Decreased sleep quality can reduce the body's immune system to fight developing cancer cells. The recommended nursing action to overcome sleep disorders in breast cancer patients undergoing chemotherapy is web-based progressive muscle relaxation (PMR). PMR is a technique that focuses attention on muscle activity, by identifying tense muscles and then reducing tension by performing relaxation techniques to get a relaxed feeling. The aim of this study was to determine the effectiveness of web-based PMR on sleep quality in breast cancer patients undergoing chemotherapy at RSUP Dr. M. Djamil Padang. The research design uses a quasi-experiment in the form of a one group pretest-posttest approach. The sampling technique was purposive sampling with a sample size of 25 people. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Statistical test using Paired T-Test. The results showed a significant effect of web-based progressive muscle relaxation (PMR) on sleep quality in breast cancer patients undergoing chemotherapy (p value = 0.000; ? < 0.05). In this study, it can be concluded that there is an influence of web-based progressive muscle relaxation (PMR) on sleep quality in breast cancer patients undergoing chemotherapy at RSUP Dr. M. Djamil Padang. This study recommends web-based progressive muscle relaxation (PMR) as an independent nursing intervention to improve sleep quality in breast cancer patients undergoing chemotherapy. Keywords: Progressive Muscle Relaxation (PMR); breast cancer; chemotherapy; sleep quality
{"title":"EFFECTIVENESS OF WEB-BASED PROGRESSIVE MUSCLE RELAXATION (PMR) ON SLEEP QUALITY IN PATIENTS BREAST CANCER UNDERGOING CHEMOTHERAPY","authors":"Weny Amelia, Dian Febrida, Armein Syahid, Espasari, CHEMOTHERAPY.. Weny Amelia1, Dian Febrida Sari2, Armein Syahid3","doi":"10.24843/mu.2024.v13.i07.p02","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p02","url":null,"abstract":"Breast cancer is the uncontrolled growth of cells or tissue in the breast. Chemotherapy is the first therapeutic choice for treating cancer. One of the symptoms felt by breast cancer patients undergoing chemotherapy is a decrease in sleep quality. Sleep quality is a person's sense of satisfaction with their sleep. Decreased sleep quality can reduce the body's immune system to fight developing cancer cells. The recommended nursing action to overcome sleep disorders in breast cancer patients undergoing chemotherapy is web-based progressive muscle relaxation (PMR). PMR is a technique that focuses attention on muscle activity, by identifying tense muscles and then reducing tension by performing relaxation techniques to get a relaxed feeling. The aim of this study was to determine the effectiveness of web-based PMR on sleep quality in breast cancer patients undergoing chemotherapy at RSUP Dr. M. Djamil Padang. The research design uses a quasi-experiment in the form of a one group pretest-posttest approach. The sampling technique was purposive sampling with a sample size of 25 people. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Statistical test using Paired T-Test. The results showed a significant effect of web-based progressive muscle relaxation (PMR) on sleep quality in breast cancer patients undergoing chemotherapy (p value = 0.000; ? < 0.05). In this study, it can be concluded that there is an influence of web-based progressive muscle relaxation (PMR) on sleep quality in breast cancer patients undergoing chemotherapy at RSUP Dr. M. Djamil Padang. This study recommends web-based progressive muscle relaxation (PMR) as an independent nursing intervention to improve sleep quality in breast cancer patients undergoing chemotherapy. \u0000 \u0000Keywords: Progressive Muscle Relaxation (PMR); breast cancer; chemotherapy; sleep quality","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"4 7‐8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ischemic stroke is a neurological condition due to the blockage of cerebral arteries or veins, leading to disrupted blood flow and oxygen supply to the brain. One of the causes of ischemic stroke is abnormalities in lipid profile levels. This study aims to determine the correlation between lipid profiles with the length of stay and clinical outcomes in patients with ischemic stroke. This study is cross-sectional research using secondary data from ischemic stroke patients admitted to Prof. Dr. I Goesti Ngoerah Gde Ngoerah General Hospital between January 1, 2021, and January 31, 2023, who meet the inclusion and exclusion criteria. Out of 215 study subjects included in this research, 137 (63.7%) were male, and 78 were female. Additionally, 192 (89.3%) were aged ? 45 years, and 23 (10.7%) were <45 years. Spearman's analysis showed a weak negative correlation between the length of stay and total cholesterol levels (r = 0.174, p = 0.010), LDL (r = 0.152, p = 0.026), and HDL (r = 0.141, p = 0.039), but no significant correlation was found with triglyceride levels (r = 0.020, p = 0.767). The results of this study also indicated a correlation between clinical outcomes and total cholesterol (p = 0.029) and LDL (p = 0.039), but not with triglyceride levels (p = 0.090) and HDL (p = 0.115). However, further research with a cohort method is needed to establish a direct correlation between lipid profiles with length of stay and clinical outcomes in ischemic stroke patients. Keywords : Ischemic Stroke, Length of Stay, Outcome
{"title":"The Correlation Between Lipid Profiles with Length of Stay and Clinical Outcomes of Ischemic Stroke Patients at Prof. Dr. I Goesti Ngoerah Gde Ngoerah General Hospital","authors":"Pande Kadek, Putri Rahayu Indrayani, Wayan Putu, Sutirta Yasa, Anak Agung, Wiradewi Lestari, Nyoman Wande","doi":"10.24843/mu.2024.v13.i07.p04","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p04","url":null,"abstract":"Ischemic stroke is a neurological condition due to the blockage of cerebral arteries or veins, leading to disrupted blood flow and oxygen supply to the brain. One of the causes of ischemic stroke is abnormalities in lipid profile levels. This study aims to determine the correlation between lipid profiles with the length of stay and clinical outcomes in patients with ischemic stroke. This study is cross-sectional research using secondary data from ischemic stroke patients admitted to Prof. Dr. I Goesti Ngoerah Gde Ngoerah General Hospital between January 1, 2021, and January 31, 2023, who meet the inclusion and exclusion criteria. Out of 215 study subjects included in this research, 137 (63.7%) were male, and 78 were female. Additionally, 192 (89.3%) were aged ? 45 years, and 23 (10.7%) were <45 years. Spearman's analysis showed a weak negative correlation between the length of stay and total cholesterol levels (r = 0.174, p = 0.010), LDL (r = 0.152, p = 0.026), and HDL (r = 0.141, p = 0.039), but no significant correlation was found with triglyceride levels (r = 0.020, p = 0.767). The results of this study also indicated a correlation between clinical outcomes and total cholesterol (p = 0.029) and LDL (p = 0.039), but not with triglyceride levels (p = 0.090) and HDL (p = 0.115). However, further research with a cohort method is needed to establish a direct correlation between lipid profiles with length of stay and clinical outcomes in ischemic stroke patients. \u0000Keywords : Ischemic Stroke, Length of Stay, Outcome","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.24843/mu.2024.v13.i07.p05
Kadek Dinda Ayu Sri Winanti, I. Sumardika, A. W. Indrayani, A. Mahendra
Background: Pigeon pea (Cajanus cajan [L] Millsp) is a type of legume rich in phytochemical compounds, phenolic compounds, flavonoids, tannins and anthocyanins. Bacillus subtilis is a microbe with excellent physiological characteristics. This study aims to determine the effect of pigeon pea fermentation by B. subtilis FNCC 0059 on the phytochemical characteristics and antioxidant activity of the extract in vitro. Methods: The study was a true experimental post test only control group design method. The samples were divided into 6 groups, the control group consisted of a negative control group, 1 ml of 0.1 mM DPPH plus 1 ml of methanol, and the positive control, 1 ml of quercetin solution plus 1 ml of 0.1 mM DPPH and the treatment group with variations in fermentation time of 16 hours. 24 hours, 32 hours and 40 hours, 1 ml of sample plus 1 ml of 0.1 mM DPPH (1:1). The data were analyzed using a data processing application and One Way Anova method. Results: The levels of total phenols, flavonoids and tannins increased highest at 24 hours of fermentation, while anthocyanins at 16 hours of fermentation. The best antioxidant activity test was at 40 hours of fermentation. Conclusion: Fermentation duration has no effect on the phytochemical characteristics and antioxidant activity of the extract. Keywords: Antioxidant activity, Phytochemical Compounds, Pigeon pea, Effect of fermentation time, Bacillus subtilis FNCC 0059.
{"title":"The effect OF FERMENTATION TIME BY BACILLUS SUBTILIS STRAIN FNCC 0059 ON THE CONTENT OF PHYTOCHEMICAL COMPOUNDS AND ANTIOXIDANT ACTIVITY IN VITRO FROM UNDIS BEAN (CAJANUS CAJAN [L.] MILLSP)","authors":"Kadek Dinda Ayu Sri Winanti, I. Sumardika, A. W. Indrayani, A. Mahendra","doi":"10.24843/mu.2024.v13.i07.p05","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p05","url":null,"abstract":"Background: Pigeon pea (Cajanus cajan [L] Millsp) is a type of legume rich in phytochemical compounds, phenolic compounds, flavonoids, tannins and anthocyanins. Bacillus subtilis is a microbe with excellent physiological characteristics. This study aims to determine the effect of pigeon pea fermentation by B. subtilis FNCC 0059 on the phytochemical characteristics and antioxidant activity of the extract in vitro. \u0000Methods: The study was a true experimental post test only control group design method. The samples were divided into 6 groups, the control group consisted of a negative control group, 1 ml of 0.1 mM DPPH plus 1 ml of methanol, and the positive control, 1 ml of quercetin solution plus 1 ml of 0.1 mM DPPH and the treatment group with variations in fermentation time of 16 hours. 24 hours, 32 hours and 40 hours, 1 ml of sample plus 1 ml of 0.1 mM DPPH (1:1). The data were analyzed using a data processing application and One Way Anova method. \u0000Results: The levels of total phenols, flavonoids and tannins increased highest at 24 hours of fermentation, while anthocyanins at 16 hours of fermentation. The best antioxidant activity test was at 40 hours of fermentation. \u0000Conclusion: Fermentation duration has no effect on the phytochemical characteristics and antioxidant activity of the extract. \u0000Keywords: Antioxidant activity, Phytochemical Compounds, Pigeon pea, Effect of fermentation time, Bacillus subtilis FNCC 0059.","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"42 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141688130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-02DOI: 10.24843/mu.2024.v13.i07.p01
Wilbert Purnamsidi, Made Krisna Dinata, I. Putu, Gede Adiatmika, Alena Juliani Sugianto, Jurnal Medika, Udayana Jurnal, Medika Udayana
The Covid-19 pandemic requires people to wear masks as a preventive measure. In addition, exercise is also highly recommended because it can prevent metabolic and infectious diseases by boosting the immune system. During this period, the government issued several regulations regarding the obligation to wear masks which certainly affected people's sports activities, especially in public spaces such as Puputan Margarana Renon Field, Denpasar City. This study was conducted by means of visual observation to count the number of people who use masks and the types of masks used when exercising. The observations made obtained a total sample of 2023 people. A total of 737 people (36.43%) used masks while 1286 people (63.57%) did not use masks. This low prevalence of mask use can be based on several factors such as concern, discomfort, and non-compliance. The 737 mask users are divided into several types of masks used, including surgical masks (45.45%), KF94 masks (17.91%), duckbill masks (17.91%), cloth masks (8.01%), scuba masks (4.48%), and cloth mask with valves (0.81%). Each of these masks has its advantages assessed through the aspects of effectiveness, price, tightness, and various other aspects. Through this study, it can be concluded that the prevalence of using masks when exercising at Puputan Margarana Renon Field, Denpasar City is still quite low (36.43%) with the most commonly used masks being surgical masks (45.45%).
Covid-19 大流行要求人们佩戴口罩作为预防措施。此外，还强烈建议人们多做运动，因为运动可以通过增强免疫系统来预防新陈代谢疾病和传染病。在此期间，政府颁布了几项关于佩戴口罩义务的规定，这无疑影响了人们的体育活动，尤其是在登巴萨市 Puputan Margarana Renon Field 等公共场所。本研究通过目视观察的方式来统计运动时使用口罩的人数和口罩的类型。观察共获得 2023 个样本。共有 737 人（36.43%）使用口罩，1286 人（63.57%）不使用口罩。口罩使用率低的原因有几个，如担心、不适和不遵守规定。这 737 名口罩使用者使用的口罩分为几种类型，包括外科口罩（45.45%）、KF94 口罩（17.91%）、鸭嘴口罩（17.91%）、布制口罩（8.01%）、水肺口罩（4.48%）和带阀门的布制口罩（0.81%）。从效果、价格、密封性和其他各方面评估，这些口罩各有优势。通过这项研究，可以得出结论：在登巴萨市 Puputan Margarana Renon Field 锻炼时使用口罩的比例仍然很低（36.43%），最常用的口罩是外科口罩（45.45%）。
{"title":"PREVALENCE OF MASK USE DURING EXERCISE AT PUPUTAN MARGARANA RENON FIELD, DENPASAR CITY DURING THE COVID-19 PANDEMIC","authors":"Wilbert Purnamsidi, Made Krisna Dinata, I. Putu, Gede Adiatmika, Alena Juliani Sugianto, Jurnal Medika, Udayana Jurnal, Medika Udayana","doi":"10.24843/mu.2024.v13.i07.p01","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i07.p01","url":null,"abstract":"The Covid-19 pandemic requires people to wear masks as a preventive measure. In addition, exercise is also highly recommended because it can prevent metabolic and infectious diseases by boosting the immune system. During this period, the government issued several regulations regarding the obligation to wear masks which certainly affected people's sports activities, especially in public spaces such as Puputan Margarana Renon Field, Denpasar City. This study was conducted by means of visual observation to count the number of people who use masks and the types of masks used when exercising. The observations made obtained a total sample of 2023 people. A total of 737 people (36.43%) used masks while 1286 people (63.57%) did not use masks. This low prevalence of mask use can be based on several factors such as concern, discomfort, and non-compliance. The 737 mask users are divided into several types of masks used, including surgical masks (45.45%), KF94 masks (17.91%), duckbill masks (17.91%), cloth masks (8.01%), scuba masks (4.48%), and cloth mask with valves (0.81%). Each of these masks has its advantages assessed through the aspects of effectiveness, price, tightness, and various other aspects. Through this study, it can be concluded that the prevalence of using masks when exercising at Puputan Margarana Renon Field, Denpasar City is still quite low (36.43%) with the most commonly used masks being surgical masks (45.45%).","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"135 1‐2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141686937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-22DOI: 10.24843/mu.2024.v13.i04.p15
Ni Nyoman Ira Santi Wedari, Dudut Rustyadi, Henky Henky, I. B. Alit
Aborsi berarti penghentian kehamilan. Aborsi dapat menimbulkan efek negatif yakni risiko fisik dan psikis apabila tidak dilakukan dengan prosedur medis. Pelaksanaan abortus provocatus medicinalis diatur pada2 UU No. 36 Tahun 2009 mengenai Kesehatan serta PP No. 61 Tahun 2014 mengenai Kesehatan Reproduksi. Sedangkan abortus provokatus criminalis, menggunakan peraturan berdasarkan KUHP Buku II mengenai Kejahatan Terhadap Nyawa. Jenis rancangan penelitian ini adalah deskriptif dengan studi potong lintang (cross-sectional). Sebanyak 104 responden perempuan usia reproduktif 15-49 tahun yang bertempat tinggal di Denpasar dijadikan subjek penelitian. Data diambil menggunakan kuesioner yang berisikan identitas responden dan 20 buah pertanyaan mengenai peraturan aborsi. Tingkat pengetahuan perempuan berusia 15-49 tahun di Denpasar perihal peraturan perundang-undangan aborsi sebesar 71,6%. Beberapa faktor yang dapat memberikan pengaruh terhadap pengetahuan pada penelitian ini yaitu usia, sebagian besar responden terdiri dari perempuan berusia 20-24 tahun yakni sebanyak 43 responden (41,3%) dan tingkat pendidikan yang terbanyak yakni SMA/sederajat dengan jumlah 57 responden (54,8%). Sebagian besar responden tidak sedang bekerja yakni sebanyak 61 responden (58,7%). Serta, sebagian besar responden tidak pernah memperoleh informasi mengenai peraturan perundang-undangan aborsi yakni sebanyak 67 responden (64,4%). Kata kunci : Tingkat pengetahuan, peraturan aborsi, dan usia reproduktif
{"title":"GAMBARAN TINGKAT PENGETAHUAN DAN FAKTOR-FAKTOR YANG MEMENGARUHI PENGETAHUAN PEREMPUAN USIA REPRODUKTIF (15-49 TAHUN) DI DENPASAR MENGENAI PERATURAN PERUNDANG-UNDANGAN ABORSI","authors":"Ni Nyoman Ira Santi Wedari, Dudut Rustyadi, Henky Henky, I. B. Alit","doi":"10.24843/mu.2024.v13.i04.p15","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i04.p15","url":null,"abstract":"Aborsi berarti penghentian kehamilan. Aborsi dapat menimbulkan efek negatif yakni risiko fisik dan psikis apabila tidak dilakukan dengan prosedur medis. Pelaksanaan abortus provocatus medicinalis diatur pada2 UU No. 36 Tahun 2009 mengenai Kesehatan serta PP No. 61 Tahun 2014 mengenai Kesehatan Reproduksi. Sedangkan abortus provokatus criminalis, menggunakan peraturan berdasarkan KUHP Buku II mengenai Kejahatan Terhadap Nyawa. Jenis rancangan penelitian ini adalah deskriptif dengan studi potong lintang (cross-sectional). Sebanyak 104 responden perempuan usia reproduktif 15-49 tahun yang bertempat tinggal di Denpasar dijadikan subjek penelitian. Data diambil menggunakan kuesioner yang berisikan identitas responden dan 20 buah pertanyaan mengenai peraturan aborsi. Tingkat pengetahuan perempuan berusia 15-49 tahun di Denpasar perihal peraturan perundang-undangan aborsi sebesar 71,6%. Beberapa faktor yang dapat memberikan pengaruh terhadap pengetahuan pada penelitian ini yaitu usia, sebagian besar responden terdiri dari perempuan berusia 20-24 tahun yakni sebanyak 43 responden (41,3%) dan tingkat pendidikan yang terbanyak yakni SMA/sederajat dengan jumlah 57 responden (54,8%). Sebagian besar responden tidak sedang bekerja yakni sebanyak 61 responden (58,7%). Serta, sebagian besar responden tidak pernah memperoleh informasi mengenai peraturan perundang-undangan aborsi yakni sebanyak 67 responden (64,4%). \u0000Kata kunci : Tingkat pengetahuan, peraturan aborsi, dan usia reproduktif","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"61 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140675687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-22DOI: 10.24843/mu.2024.v13.i04.p18
A. A. A. V. Pradnyandari, I. Wardana, I. Widianti, Muliani Muliani
Dismenore primer adalah masalah yang sering ditemukan ketika seseorang mengalami menstruasi. Dismenore primer menjadi salah satu kondisi yang dapat berpengaruh terhadap pelaksanaan aktivitas sehari-hari. Penelitian ini bertujuan untuk mengetahui prevalensi dismenore primer serta hubungan antara dismenore primer dengan aktivitas akademik dan non akademik pada mahasiswi jenjang Sarjana Kedokteran angkatan tahun 2019-2021. Desain penelitian ini menggunakan pendekatan cross sectional analitik. Sebanyak 228 mahasiswi sebagai subjek penelitian diambil melalui teknik purposive sampling kemudian dilakukan pengambilan data dalam bentuk survei dengan penyebaran kuesioner secara online. Variabel dependen pada penelitian ini adalah dismenore primer, sedangkan variabel independennya adalah aktivitas akademik dan non akademik. Analisis statistik menggunakan uji Chi Square dengan signifikansi ?=0,05. Hasil penelitian pada variabel aktivitas akademik maupun non akademik, didapatkan nilai p=0,001 dan p=0,004 yang menandakan bahwa terdapat hubungan antara dismenore primer dengan aktivitas akademik dan non akademik pada mahasiswi jenjang Sarjana Kedokteran angkatan tahun 2019-2021. Prevalensi dismenore primer paling banyak ditemukan pada angkatan 2020 yakni sebanyak 46,1%. Tidak didapatkan hubungan antara dismenore primer dengan usia menarche, indeks massa tubuh, riwayat keluarga, durasi menstruasi serta aktivitas fisik. Namun, dismenore primer berpengaruh terhadap aktivitas akademik dan non akademik mereka.
原发性痛经是指月经来潮时经常出现的问题。原发性痛经会影响日常活动的进行。本研究旨在确定 2019-2021 年医学本科生原发性痛经的患病率以及原发性痛经与学术和非学术活动之间的关系。本研究设计采用分析性横断面方法。通过目的性抽样技术共抽取了 228 名女学生作为研究对象，然后通过在线发放问卷的形式进行数据收集。本研究的因变量为原发性痛经，自变量为学术活动和非学术活动。统计分析采用卡方检验，显著性为 0.05。关于学术活动和非学术活动变量的研究结果，得到了 p = 0.001 和 p = 0.004 的值，这表明 2019-2021 年医学本科生的原发性痛经与学术活动和非学术活动之间存在关系。原发性痛经在 2020 级学生中发病率最高，为 46.1%。原发性痛经与初潮年龄、体重指数、家族史、月经持续时间和体育活动之间没有关系。然而，原发性痛经影响了她们的学习和非学习活动。
{"title":"HUBUNGAN DISMENORE PRIMER DENGAN AKTIVITAS AKADEMIK DAN NON AKADEMIK PADA MAHASISWI JENJANG SARJANA KEDOKTERAN ANGKATAN TAHUN 2019-2021","authors":"A. A. A. V. Pradnyandari, I. Wardana, I. Widianti, Muliani Muliani","doi":"10.24843/mu.2024.v13.i04.p18","DOIUrl":"https://doi.org/10.24843/mu.2024.v13.i04.p18","url":null,"abstract":"Dismenore primer adalah masalah yang sering ditemukan ketika seseorang mengalami menstruasi. Dismenore primer menjadi salah satu kondisi yang dapat berpengaruh terhadap pelaksanaan aktivitas sehari-hari. Penelitian ini bertujuan untuk mengetahui prevalensi dismenore primer serta hubungan antara dismenore primer dengan aktivitas akademik dan non akademik pada mahasiswi jenjang Sarjana Kedokteran angkatan tahun 2019-2021. Desain penelitian ini menggunakan pendekatan cross sectional analitik. Sebanyak 228 mahasiswi sebagai subjek penelitian diambil melalui teknik purposive sampling kemudian dilakukan pengambilan data dalam bentuk survei dengan penyebaran kuesioner secara online. Variabel dependen pada penelitian ini adalah dismenore primer, sedangkan variabel independennya adalah aktivitas akademik dan non akademik. Analisis statistik menggunakan uji Chi Square dengan signifikansi ?=0,05. Hasil penelitian pada variabel aktivitas akademik maupun non akademik, didapatkan nilai p=0,001 dan p=0,004 yang menandakan bahwa terdapat hubungan antara dismenore primer dengan aktivitas akademik dan non akademik pada mahasiswi jenjang Sarjana Kedokteran angkatan tahun 2019-2021. Prevalensi dismenore primer paling banyak ditemukan pada angkatan 2020 yakni sebanyak 46,1%. Tidak didapatkan hubungan antara dismenore primer dengan usia menarche, indeks massa tubuh, riwayat keluarga, durasi menstruasi serta aktivitas fisik. Namun, dismenore primer berpengaruh terhadap aktivitas akademik dan non akademik mereka.","PeriodicalId":518119,"journal":{"name":"E-Jurnal Medika Udayana","volume":"42 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140677572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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