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Synthesis, Characterization and Evaluation of the Biological Activity of Some New Thiazolidine Derivatives Derived from Schiff bases 席夫碱衍生噻唑烷类化合物的合成、表征及生物活性评价
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.03.20
Hussam Z. Naji, Eman M. Hussain
In this research, new compounds were synthesized via the reaction of dichloroacetic acid with two moles of piperidine. The novel acid 1 was converted to its ester 2. Acid hydrizide 3 was prepared by the reaction of hydrazine hydrate with new ester 2, which was later used to prepare derivatives of Schiff bases 4-13. In the last step, Schiff bases and thioglycolic acid were reacted to give thiazolidine derivatives 14-23. All these compounds were diagnosed using melting points, FTIR, 1HNMR and mass spectroscopy. Scheme 1 shows all the synthesized compounds' reaction steps and structures. Keywords: Thiazolidine; Schiff bases; biological activity; piperidine; dichloroacetic acid.
本研究通过二氯乙酸与2摩尔哌替啶的反应合成了新的化合物。这种新型酸被转化成它的酯。由水合肼与新酯2反应制备酸肼3,并将其用于制备希夫碱4-13衍生物。最后一步,席夫碱与巯基乙酸反应生成噻唑烷衍生物14-23。所有化合物都通过熔点、FTIR、1HNMR和质谱进行了诊断。图1显示了所有合成化合物的反应步骤和结构。关键词:Thiazolidine;希夫碱;生物活性;哌啶;二氯乙酸。
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引用次数: 0
Studying the Genetic Parameters of Some Cultivars of Faba Bean (Vicia faba L.) and Evaluating Their Performance under Different Levels of Phosphorous 不同磷水平下蚕豆品种遗传参数研究及性能评价
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.03.78
Ali H. Algraishi, Faez F. Alogaidi
A field experiment was carried out during the winter season of 2021-2022 in the research station - College of Agricultural Engineering Sciences - University of Baghdad in order to study the genetic parameters of some cultivars of faba bean cultivars and evaluate their performance under different levels of phosphorus. Spilled plots were arranged according to randomized complete block design (RCBD) at three replications. The main plots included three levels of phosphorous fertilizer (80, 120 and 160 Kg ha-1 ) and the control treatment (without fertilizer). In contrast, the subplots included four faba bean cultivars (Local, Spanish, Dutch and New Zealand). The results showed highly significant effects of phosphorous fertilizer levels on the most studied traits, as adding phosphorous fertilizer at 160 Kg gave the highest means of several pods per plant (17.78 pods plant-1 ) and seed yield (4.403 tons ha-1 ). Also, the results showed that the faba bean cultivars were significantly different in most studied traits, as the Local cultivar achieved the highest mean number of pods per plant (16.95pod plant-1 ). In contrast, the Dutch cultivar achieved the highest mean number of seeds per pod (5.78 seed pod-1 ), whereas the Spanish cultivar achieved the highest mean weight of 100 seeds (86.95 g) and seed yield (5.295 ton ha-1 ). The interaction between studied factors had a non-significant effect on all studied traits except the number of pods per plant. The genetic variance recorded greater values than the environmental variance in most of the studied traits, indicating that the genetic variance significantly contributed to the phenotypic variance. Keywords: Genetic indicators, phosphorous, Vicia faba L., G.C.V., PCV.
为了研究部分蚕豆品种的遗传参数,并评价其在不同磷水平下的表现,于2021-2022冬季在巴格达大学农业工程科学学院研究站进行了田间试验。溢出区按随机完全区设计(RCBD)排列,每3个重复。主要样地包括3个水平磷肥(80、120和160 Kg hm -1)和对照处理(不施肥)。相比之下,子小区包括4个蚕豆品种(本地、西班牙、荷兰和新西兰)。结果表明,施磷水平对研究性状的影响非常显著,施磷水平为160 Kg时,单株荚果数最高(17.78个),籽粒产量最高(4.403 t ha-1)。结果表明,不同品种蚕豆在多数性状上存在显著差异,其中本地品种单株平均荚果数最高(16.95荚果-1)。相比之下,荷兰品种的平均每荚种子数最高(5.78粒每荚-1),而西班牙品种的平均每荚种子重最高(86.95克),种子产量最高(5.295吨每荚-1)。除单株荚果数外,各因子间的交互作用对其他性状均无显著影响。多数性状的遗传变异值大于环境变异值,表明遗传变异对表型变异有显著贡献。关键词:遗传指标,磷,蚕豆,gcv, PCV
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引用次数: 0
The expression miRNA-195 in a sample of Iraqi breast cancer patients. miRNA-195在伊拉克乳腺癌患者样本中的表达。
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.03.87
Ahmed Nasser Ibraheem AL-saqabi, Ismail Hussein Aziz
Breast carcinoma is the most prevalent cancer-related cause of death in women, and metastasis is the main factor in morbidity. The total number of new cases of cancer in Iraq during the year 2019 was 35,864. New non-invasive prognostic biomarkers are needed for the rapid recognition and differentiation between breast cancer (BC) stages for treatment choice improvement. MicroRNA (miRNA) are small, noncoding RNAs regulating gene expression and involve many cellular processes, including metastasis. Circulating miRNAs (detected in the blood) show considerable potential as biomarkers for helping diagnosis or tracking treatment efficacy. Materials and Methods: total RNA was extracted from serum from (n=50) patients and (n=26) healthy control to measure the MicroRNA 195 expression using SYBR green-based real-time RT-PCR technology. As a result, the expression levels miR-195 in breast cancer patients’ serum were significantly increased (up-regulated) compared to those in the normal adjacent serum. BC group showed a higher significant miR-195 expression (upregulation) when compared with those in the control group. While the highest expression of miR195 was recorded in stage II. Keywords: Breast Cancer, MicroRNA, miR-195, Stage, Iraq
乳腺癌是妇女中最常见的癌症相关死亡原因,而转移是发病率的主要因素。2019年,伊拉克新发癌症病例总数为35864例。需要新的非侵入性预后生物标志物来快速识别和区分乳腺癌(BC)分期,以改善治疗选择。MicroRNA (miRNA)是调节基因表达的小非编码rna,参与许多细胞过程,包括转移。循环mirna(在血液中检测到)作为帮助诊断或跟踪治疗效果的生物标志物显示出相当大的潜力。材料与方法:分别从50例患者和26例健康对照血清中提取总RNA,采用基于SYBR绿色的实时RT-PCR技术检测MicroRNA 195的表达。因此,乳腺癌患者血清中miR-195的表达水平较正常邻近血清中miR-195的表达水平显著升高(上调)。与对照组相比,BC组miR-195表达显著升高(上调)。而miR195在II期表达量最高。关键词:乳腺癌,MicroRNA, miR-195,分期,伊拉克
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引用次数: 0
FSCN1 Gene Expression Influence on Breast Cancer in Iraqi Patients FSCN1基因表达对伊拉克乳腺癌患者的影响
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.03.85
Rifaat M. Rifaat, Mohammed I. Nader
Our investigation aim was to ascertain how the Fascin actin-bundling protein 1 (FSCN1) gene affected breast cancer patients and how it affected the molecular type of the disease (Luminal A, Luminal B, Triple negative, Enrich Her2).By collecting blood samples from sixty patients with Breast cancer from many hospitals in Baghdad/Iraq between the periods (October 2021 to August 2022) and collecting forty volunteers heaths as Control. The volunteer's blood samples were collected and tested with Cancer antigen 15-3 (CA 15-3) to confirm absent breast cancer. The blood and control samples from these patients were collected, the RNA was extracted, and molecular methods using PCR and primers targeting the FSCN1 gene were used. The results showed that genes found in all patient samples have overexpression compared to healthy volunteers, and we also discovered differences in expression between the molecular types of breast cancer. We discovered that Triple-negative breast cancer is more affected than Luminal A, B, and Enrich Her2. Keywords: Breast Cancer, Molecular classification breast cancer, Fascin Actin Bundling protein 1 genes
我们的研究目的是确定FSCN1基因如何影响乳腺癌患者,以及它如何影响疾病的分子类型(Luminal A, Luminal B, Triple negative, Enrich Her2)。通过在2021年10月至2022年8月期间从巴格达/伊拉克的多家医院收集60名乳腺癌患者的血液样本,并收集40名志愿者作为对照。研究人员采集了志愿者的血液样本,并对其进行了癌症抗原15-3 (CA 15-3)检测,以确定是否存在乳腺癌。采集患者的血液和对照样本,提取RNA,采用PCR和引物靶向FSCN1基因的分子方法。结果显示,与健康志愿者相比,所有患者样本中发现的基因都有过表达,我们还发现了乳腺癌分子类型之间表达的差异。我们发现三阴性乳腺癌比Luminal A, B和Enrich Her2更受影响。关键词:乳腺癌,分子分类,束状蛋白,肌动蛋白捆绑蛋白1基因
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引用次数: 0
Estimation of Some Biochemical Tests in the Serum of Obese Men with Normal Blood Pressure and High Blood Pressure 正常血压和高血压肥胖男性血清生化指标的评价
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.04.25
Shaimaa Khalid Moufak, Rowshen Hani Al Nakeeb, Tamara Sami Naji
Obesity is a medical word that refers to a state in which a person's body fat levels are excessively high. Obesity is linked to a variety of health issues in humans, like the emergence of hypertension. This study aimed to look at the blood glucose concentration, urea, creatinine, and lipid profile factors in obese and hypertension-overweight men's sera. The study included 75 people who were evenly divided into three groups: healthy controls, normotensive obese people, and hypertension-obese people. When comparing obese males to controls, there was a significant increase (P<0.01) in blood glucose, urea, creatinine, cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and very low-density lipoprotein cholesterol (VLDL-C) although only triglycerides (TGs) and VLDL-C were substantially different in hypertension obese versus normotensive obese. Compared to controls, Obese men had significantly lower levels of high-density lipoprotein cholesterol (HDL-C). High levels of triglycerides (TGs) and Very Low-density Lipoprotein cholesterol (VLDL) in hypertensive obese males show they play a role in hypertension problems. Keywords: Obesity, Hypertension, Urea, Creatinine, lipid profile.
肥胖是一个医学词汇,指的是一个人体内脂肪水平过高的状态。肥胖与人类的多种健康问题有关,比如高血压的出现。本研究旨在观察肥胖和高血压超重男性血清中的血糖浓度、尿素、肌酐和脂质谱因素。这项研究包括75人,他们被平均分为三组:健康对照组、正常肥胖者和高血压肥胖者。当将肥胖男性与对照组进行比较时,血糖、尿素、肌酐、胆固醇、甘油三酯、低密度脂蛋白胆固醇(LDL-C)和极低密度脂蛋白胆固醇(VLDL-C)显著增加(P<0.01),尽管高血压肥胖与正常肥胖之间只有甘油三酯(TGs)和VLDL-C存在显著差异。与对照组相比,肥胖男性的高密度脂蛋白胆固醇(HDL-C)水平显著降低。高血压肥胖男性中高水平的甘油三酯(tg)和极低密度脂蛋白胆固醇(VLDL)表明它们在高血压问题中起作用。关键词:肥胖,高血压,尿素,肌酐,血脂。
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引用次数: 1
Effect of shading and fertilization with iron and sulfur on some vegetative growth and leaves mineral content of Gardenia jasminoides Ellis. 遮荫和铁硫施肥对栀子营养生长和叶片矿物质含量的影响。
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.04.14
Ali J Hussein, Mahmood. SH. Ahmed
This study was conducted in a glass house, Dept of Hort. and Landscape, College of Agriculture, Univ. Anbar, during the 2021-2022 growing season, to investigate the influence of shading and fertilization on the growth and leaf mineral content of gardenia plants. This study included two factors: two levels of shading at 0 (S0), shading 50 % (S1) and four treatments of fertilizations, control (F0), chelated iron spray at 2 ml.L-1 (F1), addition of magnesium sulfate to pots at 7 gm.plant-1 (F2) and chelated iron spray at 2 ml.L-1 + addition of magnesium sulfate to pots at 7 gm.plant-1 (F3) and their interaction. Treatments were replicated three times at Split plots design (Shading is the main plot) in an RCBD. The number of plants used was 36 plants. The results showed that interaction treatment (S1F3) significantly increased the plant height by 6.517 cm, the highest increase in shoot length of 11.267 cm, and the number of 94.107 leaves.plant-1 , highest leaf area of 9437.463 cm2 , highest leaf nitrogen content of 1.877 % and highest leaf potassium content of 0.561 %, while lower values of these traits were in interaction treatment (S0F0). Keywords: iron, sulfur, vegetative growth, Gardenia jasminoides Ellis
这项研究是在一个玻璃房子里进行的。在2021-2022年生长季节,研究遮荫和施肥对栀子植物生长和叶片矿物质含量的影响。本研究包括2个因素:遮荫0 (S0)、遮荫50% (S1)和施肥、对照(F0)、螯合铁喷施2 ml.L-1 (F1)、盆栽中添加硫酸镁7 mg .plant-1 (F2)和螯合铁喷施2 ml.L-1 +盆栽中添加硫酸镁7 mg .plant-1 (F3) 4个处理及其相互作用。在RCBD中,以分裂样地设计(阴影为主要样地)重复处理三次。植株数量为36株。结果表明:互作处理(S1F3)显著提高了株高6.517 cm,最高增加了茎长11.267 cm,叶片数94.107片;植株-1的叶面积最高,为9437.463 cm2,叶片氮含量最高,为1.877%,叶片钾含量最高,为0.561%,而互作处理(so0f0)的这些性状值较低。关键词:铁,硫,营养生长,栀子
{"title":"Effect of shading and fertilization with iron and sulfur on some vegetative growth and leaves mineral content of Gardenia jasminoides Ellis.","authors":"Ali J Hussein, Mahmood. SH. Ahmed","doi":"10.21931/rb/css/2023.08.04.14","DOIUrl":"https://doi.org/10.21931/rb/css/2023.08.04.14","url":null,"abstract":"This study was conducted in a glass house, Dept of Hort. and Landscape, College of Agriculture, Univ. Anbar, during the 2021-2022 growing season, to investigate the influence of shading and fertilization on the growth and leaf mineral content of gardenia plants. This study included two factors: two levels of shading at 0 (S0), shading 50 % (S1) and four treatments of fertilizations, control (F0), chelated iron spray at 2 ml.L-1 (F1), addition of magnesium sulfate to pots at 7 gm.plant-1 (F2) and chelated iron spray at 2 ml.L-1 + addition of magnesium sulfate to pots at 7 gm.plant-1 (F3) and their interaction. Treatments were replicated three times at Split plots design (Shading is the main plot) in an RCBD. The number of plants used was 36 plants. The results showed that interaction treatment (S1F3) significantly increased the plant height by 6.517 cm, the highest increase in shoot length of 11.267 cm, and the number of 94.107 leaves.plant-1 , highest leaf area of 9437.463 cm2 , highest leaf nitrogen content of 1.877 % and highest leaf potassium content of 0.561 %, while lower values of these traits were in interaction treatment (S0F0). Keywords: iron, sulfur, vegetative growth, Gardenia jasminoides Ellis","PeriodicalId":52287,"journal":{"name":"Revista Bionatura","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136183128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The role of adding potassium humate and foliar spraying with marine algae on the mineral content and nutritional value of Moringa 添加腐植酸钾和叶面喷施海藻对辣木矿物质含量和营养价值的影响
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.04.05
Sarbaz Faki Jaafar Omar, Jassim Mohammad Aziz Al-Jubouri
An experiment was carried out in the plastic house at the Agricultural Research Station in Bani Maqam, affiliated to Jam Jamal Agriculture Directorate in Sulaymaniyah Governorate, in a randomized complete block design, with three replications, on June 10, 2021. Furthermore, 4, 8, 12 and 16 kg hectares when planting and before the first irrigation and after each mowing process, and the second factor was spraying with seaweed extract Alga000 at three levels 0, 1, and 2 ml (2 and 4 ml per liter of total spray) and at two intervals after 20 and 30 days of planting After 10 and 25 days of mowing, at a height of 20 cm from the surface of the ground, the mineral content of leaves and dry stems samples of the first mowing plants was estimated. It included the content of calcium, iron and manganese (mg/100g dry matter) and the percentage of nitrogen, phosphorous and potassium. Indicators of the nutritional value of the leaves and stems of the first mow, which included the estimation of the percentage of total carbohydrates, ash, protein and fiber. The results showed that adding 16 kg hectares of potassium humate and spraying at a concentration of 2 ml per liter twice with algae extract Bahriya recorded the highest content of iron (42.3 and 19.82), calcium (2103.7 and 1009.29) and manganese (40 and 10.15) mg/100 g of dry matter for leaves and stems. The highest percentage of phosphorous was 0.333% in dry leaves, and the highest percentage of nitrogen (3.89%) and 1.58%), potassium (1.601% and 1.24%), protein (24.314% and 9.885%), total carbohydrates (35.23% and 11.86%), and the lowest fiber content (4.57% and 25.45%) in the dry matter. For leaves and stems . Keywords: moringa, potassium humate, marine algae, mineral content, nutritional value
实验于2021年6月10日在苏莱曼尼亚省Jam Jamal农业局下属Bani Maqam农业研究站的塑料房里进行,采用随机完全块设计,重复3次。此外,4、8、12和16公斤公顷种植和每个修剪后的第一个灌溉和过程之前,第二个因素是与海藻萃取液Alga000喷涂三个级别0,1和2毫升(2和4毫升每升的总喷雾)和两个间隔种植20到30天后割草10到25天之后,20厘米的高度从地面的表面,叶子和茎干的矿物含量的样本估计第一个割草植物。包括钙、铁、锰含量(mg/100g干物质)和氮、磷、钾的百分比。第一季叶片和茎的营养价值指标,包括总碳水化合物、灰分、蛋白质和纤维的百分比估算。结果表明,施用16 kg hm2腐植酸钾,以2 ml / l浓度喷施2次藻提取物,叶片和茎干物质中铁(42.3和19.82 mg)、钙(2103.7和1009.29 mg)和锰(40和10.15 mg)含量最高。干叶中磷含量最高,为0.333%,干物质中氮含量最高,分别为3.89%和1.58%,钾含量分别为1.601%和1.24%,蛋白质含量分别为24.314%和9.885%,总碳水化合物含量分别为35.23%和11.86%,纤维含量最低,分别为4.57%和25.45%。叶子和茎。关键词:辣木,腐植酸钾,海藻,矿物质含量,营养价值
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引用次数: 1
Panoramic View among Other Radiographic Investigations for Dental Implant Surgery, Dentists’ Perspective 牙科种植手术的其他放射学研究的全景视图,牙医的视角
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.03.51
Sanaa Jamal Mahmood, Amaal Alnuaimy, Faaiz Alhamdani
Objectives: To determine the factors that could influence the use of OPG in dental implant surgery from a dentist’s perspective. Methods: A Google form questionnaire was circulated electronically as a google form to dentists of different dental specialties and practical backgrounds. Data were collected and analyzed using SPSS Ver.25. Statistical significance has been set at P<0.05. Results: Most participating dentists use OPG as a preoperative diagnostic tool in dental implants. Only 13 (15.1%) dentists do not use OPG in dental implant treatment. The Chi-Square Test showed a statistically significant relationship (P=0.042) between the reason for OPG request and dentists' qualifications. The overwhelming majority of PhD and Fellowship degree holder dentists (71.4%) request the OPG to view the relationship between the implant site and the vital anatomical structures. The ChiSquare Test showed a highly significant relationship (P=0.000) between the type of additional radiographic investigation and the dental specialty. Surgeons, compared to general practitioners (43.8%) and other specialties (52.6%), are favorably interested (91.4%) in CBCT as an additional diagnostic aid to OPG. Conclusions: Dentists agree on the preliminary diagnostic value of OPG in dental implant surgery. PhD and OMFS Fellowship holders seem more interested in the relationship between the dental implant position and jaw anatomical landmarks on the OPG. Oral surgeons appear to appreciate the role of CBCT as an additional preoperative diagnostic tool. Keywords: dill seeds, broilers, productive performance, carcasses.
目的:从牙医的角度探讨影响OPG在种植牙手术中应用的因素。方法:以谷歌表格的形式对不同牙科专业和实践背景的牙医进行电子问卷调查。数据收集和分析使用SPSS Ver.25。统计学意义设置为P<0.05。结果:大多数参与调查的牙医使用OPG作为种植体术前诊断工具。只有13名(15.1%)牙医在种植牙治疗中不使用OPG。卡方检验显示,申请OPG的原因与牙医资格之间存在统计学意义(P=0.042)。绝大多数拥有博士学位和奖学金学位的牙医(71.4%)要求OPG查看种植体位置和重要解剖结构之间的关系。ChiSquare检验显示,额外x线检查的类型与牙科专业之间存在高度显著的关系(P=0.000)。与全科医生(43.8%)和其他专业(52.6%)相比,外科医生(91.4%)对CBCT作为OPG的额外诊断辅助很感兴趣。结论:牙医师一致认同OPG在种植牙手术中的初步诊断价值。博士和OMFS奖学金获得者似乎对种植牙位置与OPG上颌骨解剖标志之间的关系更感兴趣。口腔外科医生似乎很欣赏CBCT作为额外的术前诊断工具的作用。关键词:莳萝籽;肉鸡;生产性能;
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引用次数: 1
A comparison with micro albuminuria indicates whether urine and serum kidney injury molecule-1 can predict the onset of early diabetic nephropathy (DN). 通过与微量蛋白尿的比较,探讨尿和血清肾损伤分子-1是否可以预测早期糖尿病肾病(DN)的发生。
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.03.46
Dalia M. Saleh, Manal K Rasheed, Nabeel K. Alwandi
Diabetic nephropathy (DN) is the most frequent consequence of DM and a significant contributor to chronic kidney disease, a multifactorial illness. Kidney injury molecule-1 (KIM-1) is a sensitive and accurate indicator of kidney damage and a predictive indicator. Aim: The present investigation aimed to examine serum and urine KIM-1 as a DN early marker. Patients and methods: The present study included 150 participants, among whom 50 non-diabetic participants were chosen as controls. One hundred diabetic participants were split into two groups based on their urine albumin/creatinine ratio (ACR) as participants with normoalbuminuria (T2DM patients without nephropathy) and microalbuminuria (T2DM patients with nephropathy). The blood glucose, HbA1c, s.urea, and creatinine levels in serum and urine were measured using standard laboratory techniques, and Elisa Essay measured serum and urine KIM-1 levels. Results: There was a distinct variation in the mean serum and urine KIM-1 between the control and diabetics without microalbuminuria (P = 0.001). Serum KIM-1 correlated with ACR (P = 0.669) in people with diabetes with microalbuminuria. Urine KIM-1 was less correlated than serum KIM-1 (p = 0.257). A strong association was found between ACR and serum KIM1 in people with diabetes with microalbuminuria and a low correlation between ACR and urine KIM-1 in people with diabetes with microalbumin. Conclusion: According to the current investigation, diabetic groups with microalbuminuria had higher serum and urine levels of KIM-1 than the control groups. Additionally, there was a favorable correlation between serum KIM-1 and the length of diabetes. More extensive multicentric trials are also needed to assess the efficacy of serum and urine KIM-1 as a DN early marker. Keywords: Serum /Urine KIM-1; Dibetic nephropathy; Microalbumin; DM type2
糖尿病肾病(DN)是糖尿病最常见的后果,也是慢性肾脏疾病的重要因素,是一种多因素疾病。肾损伤分子-1 (KIM-1)是一种灵敏、准确的肾损伤指标和预测指标。目的:本研究旨在检测血清和尿液KIM-1作为DN的早期标志物。患者和方法:本研究包括150名参与者,其中50名非糖尿病患者作为对照。100名糖尿病患者根据尿白蛋白/肌酐比值(ACR)分为正常蛋白尿(无肾病的T2DM患者)和微量蛋白尿(有肾病的T2DM患者)两组。采用标准实验室技术测定血清和尿液中的血糖、糖化血红蛋白、尿素和肌酐水平,Elisa法测定血清和尿液中的KIM-1水平。结果:无微量白蛋白尿的糖尿病患者与对照组的平均血清和尿液KIM-1有明显差异(P = 0.001)。糖尿病合并微量白蛋白尿患者血清KIM-1与ACR相关(P = 0.669)。尿KIM-1与血清KIM-1相关性较低(p = 0.257)。糖尿病伴微量白蛋白尿患者的ACR和血清KIM1之间存在很强的相关性,而糖尿病伴微量白蛋白尿患者的ACR和尿KIM-1之间存在较低的相关性。结论:根据目前的调查,糖尿病伴微量白蛋白尿组血清和尿液中KIM-1水平高于对照组。此外,血清KIM-1与糖尿病病程之间存在良好的相关性。还需要更广泛的多中心试验来评估血清和尿液KIM-1作为DN早期标志物的有效性。关键词:血清/尿KIM-1;Dibetic肾病;微白蛋白;DM type2
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引用次数: 1
Response of Local Garlic to Potassium and Sulfur Fertilization Method 地方大蒜对钾硫施肥方式的响应
Q4 Medicine Pub Date : 2023-10-15 DOI: 10.21931/rb/css/2023.08.04.11
Raed K. A. Al-Mohammadi, Maath M. M. Al-Abdaly
A field experiment was conducted at the Agricultural Research Station of the College of Agriculture, University of Anbar, for the agricultural season 2021- 2022. This experiment aimed to study the effect of potassium and sulfur application on local garlic's growth, yield, and quality. The experiment included four levels of potassium soil fertilization (0, 200, 250, and 300 kg.ha-1 ), three levels of foliar spraying of potassium (0, 5, and 10 g.L-1 ), and three levels of soil fertilization of sulfur (0, 40, and 50 kg.ha-1 ). The study used the randomized complete block design (RCBD) in combinations. The results showed significant differences in the characteristics of vegetative growth, yield characteristics, and qualitative characteristics. The combination (300 kg K2O.ha-1 +10 g.L-1 + 50 kg S.ha-1 ) significantly exceeded by giving the highest leaves number, leaves area and shoot dry weight, which amounted to 11.42 leaf.plant-1 and 795.00 cm2 .plant-1 and 10.87 g.plant-1 , respectively. In comparison, the control treatment gave (8.80 leaves.plant-1 and 571.00 cm2 .plant-1 and 8.17 g.plant-1 ), for the same above traits, respectively. The same combination achieved a significant increase in yield traits (cloves number, clove weight, yield/plant, and total yield) with 37.58 cloves, 2.71 g, 102.03 g, and 51.01 t.ha-1 , respectively, compared to the control treatment, which gave (32.00 cloves, 1.81 g, 58.17 g, and 29.08 t.ha-1 ). The same treatment led to an increase in the percentage of potassium and sulfur in the bulbs, which recorded the highest percentage of 1.67% and 0.60%, respectively, compared to the control treatment, which recorded the lowest percentage of 1.36% and 0.40%, respectively. Keywords: Garlic, Fertilization, Potassium, Sulfur, Growth, Yield.
在安巴尔大学农学院农业研究站进行了2021- 2022农业季节的田间试验。本试验旨在研究钾肥和硫肥对地方大蒜生长、产量和品质的影响。试验分0、200、250、300 kg 4个施肥水平。Ha-1),三个水平的叶面喷钾(0、5和10 g)。L-1),以及三个水平的土壤硫施肥(0、40和50 kg)。农业)。该研究采用随机完全区组设计(RCBD)进行组合。结果表明,在营养生长特征、产量特征和质量特征上存在显著差异。组合(300 kg K2O)。Ha-1 + 10g。L-1 + 50 kg S.ha-1)的叶片数、叶面积和地上部干重均达到最高,达到11.42片。Plant-1、Plant-1、Plant-1分别为795.00 cm2和10.87 gm2。对照处理的叶片数量为8.80片。植株-1和8.17 g.plant-1分别为571.00 cm2和8.17 g.plant-1。与对照处理(32.00瓣、1.81 g、58.17 g和29.08 t.ha-1)相比,同一组合处理的产量性状(丁香数、丁香重、单株产量和总产量)分别为37.58瓣、2.71 g、102.03 g和51.01 t.ha-1)显著提高。同样处理导致鳞茎中钾和硫的百分比分别增加了1.67%和0.60%,而对照处理的百分比最低,分别为1.36%和0.40%。关键词:大蒜,施肥,钾,硫,生长,产量
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引用次数: 1
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