首页 > 最新文献

Nutrition Clinique et Metabolisme最新文献

英文 中文
Prevalence of malnutrition, dietary trends, and oral nutritional supplements use among Algerian cancer outpatients undergoing chemotherapy 阿尔及利亚接受化疗的癌症门诊患者的营养不良患病率、饮食趋势和口服营养补充剂使用情况
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-04-10 DOI: 10.1016/j.nupar.2024.01.002
Abderrezak Kennas , Saliha Makhoukh , Kahina Derrar , Katia Hadji

Objective

It is widely acknowledged that patients with cancer commonly experience malnutrition, and some individuals may adopt specific dietary trends. This study investigated the prevalence of malnutrition and dietary trends among Algerian cancer outpatients undergoing chemotherapy.

Material and methods

This cross-sectional, descriptive study was conducted from January to October 2023 with 71 cancer outpatients undergoing chemotherapy. Malnutrition risk was evaluated using the Malnutrition Screening Tool (MST). The questionnaire also collected the occurrence of nutrition impact symptoms, the avoidance of specific food groups, and the use of oral nutritional supplements and dietary supplements.

Results

Malnutrition risk was identified in 57.7% (41 cases) of participants. Nutrition impact symptoms were reported by 59.2% (42 cases) of patients. A total of 36 of the patients (50.7%) altered their eating habits by avoiding at least one food group. Among malnourished cancer outpatients, only five used oral nutritional supplements. Dietary supplements were used by 23.9% (27/71) of the patients after cancer diagnosis.

Conclusion

Our findings underscore the necessity for a systematic malnutrition assessment in cancer patients. Qualified clinicians should provide nutritional awareness to enhance the quality of life for these patients.

目的人们普遍认为,癌症患者通常会出现营养不良,有些人可能会形成特定的饮食习惯。本研究调查了阿尔及利亚接受化疗的癌症门诊患者中营养不良的发生率和饮食趋势。材料和方法本横断面描述性研究于 2023 年 1 月至 10 月对 71 名接受化疗的癌症门诊患者进行了调查。采用营养不良筛查工具(MST)对营养不良风险进行评估。调查问卷还收集了营养影响症状的发生情况、特定食物组的忌口情况以及口服营养补充剂和膳食补充剂的使用情况。59.2%的患者(42 例)报告了营养影响症状。共有 36 名患者(50.7%)改变了饮食习惯,避免进食至少一类食物。在营养不良的癌症门诊患者中,只有五人使用口服营养补充剂。23.9%的患者(27/71)在确诊癌症后使用了膳食补充剂。合格的临床医生应为这些患者提供营养知识,以提高他们的生活质量。
{"title":"Prevalence of malnutrition, dietary trends, and oral nutritional supplements use among Algerian cancer outpatients undergoing chemotherapy","authors":"Abderrezak Kennas ,&nbsp;Saliha Makhoukh ,&nbsp;Kahina Derrar ,&nbsp;Katia Hadji","doi":"10.1016/j.nupar.2024.01.002","DOIUrl":"10.1016/j.nupar.2024.01.002","url":null,"abstract":"<div><h3>Objective</h3><p>It is widely acknowledged that patients with cancer commonly experience malnutrition, and some individuals may adopt specific dietary trends. This study investigated the prevalence of malnutrition and dietary trends among Algerian cancer outpatients undergoing chemotherapy.</p></div><div><h3>Material and methods</h3><p>This cross-sectional, descriptive study was conducted from January to October 2023 with 71 cancer outpatients undergoing chemotherapy. Malnutrition risk was evaluated using the Malnutrition Screening Tool (MST). The questionnaire also collected the occurrence of nutrition impact symptoms, the avoidance of specific food groups, and the use of oral nutritional supplements and dietary supplements.</p></div><div><h3>Results</h3><p>Malnutrition risk was identified in 57.7% (41 cases) of participants. Nutrition impact symptoms were reported by 59.2% (42 cases) of patients. A total of 36 of the patients (50.7%) altered their eating habits by avoiding at least one food group. Among malnourished cancer outpatients, only five used oral nutritional supplements. Dietary supplements were used by 23.9% (27/71) of the patients after cancer diagnosis.</p></div><div><h3>Conclusion</h3><p>Our findings underscore the necessity for a systematic malnutrition assessment in cancer patients. Qualified clinicians should provide nutritional awareness to enhance the quality of life for these patients.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 2","pages":"Pages 88-94"},"PeriodicalIF":0.6,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140791838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oil-extracted from flaxseeds protects against endothelial dysfunction and oxidative stress by modulating nitric oxide, thiols contents and improving redox status in ouabain-induced hypertensive rats 亚麻籽萃取油通过调节一氧化氮、硫醇含量和改善氧化还原状态,保护乌巴因诱导的高血压大鼠免受内皮功能障碍和氧化应激的影响
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-04-10 DOI: 10.1016/j.nupar.2024.02.003
Sadia Berzou , Fatima Zohra Labbaci , Akila Guenzet , Nawal Dida-Taleb , Hakima Mir , Djamil Krouf

Objectives

The purpose of this study was to evaluate the antihypertensive and antioxidant effects of flaxseed oil in ouabain-induced hypertensive in normal rats Wistar.

Methods

Experimental hypertension was induced by a daily subcutaneous (sc) injection of 10 μg/kg/day/rat of ouabain diluted in 9 g/L of saline solution (NaCl) for 21 days (n = 16). Animals were then divided into two groups fed an experimental diet containing 20% casein supplemented (Ouab-Oil-Lu) or not (Ouab) with 1% flaxseed oil whereas control rats (n = 8) received only a daily sc injection of NaCl.

Results

The results showed that supplementing hypertensive rats with 1% flaxseed oil decreased significantly (P < 0.05) the systolic, diastolic, and mean arterial pressure, ameliorated plasma and liver lipid profile and reduced glucose levels in plasma. Similarly, flaxseed oil decreased TBARS levels in plasma and tissues, as well as carbonyl levels in the heart. Interestingly, this supplementation increased GSH, thiols and nitric oxide levels and improved AchE and antioxidant enzyme activities (SOD and GSH-Px) in the tissues.

Conclusions

Our findings suggested that flaxseed oil may provide a rationale for antihypertensive use in traditional medicine.

本研究的目的是评估亚麻籽油对乌巴因诱导的正常 Wistar 大鼠高血压的降压和抗氧化作用。方法通过每天皮下注射 10 μg/kg/ 天/只大鼠的乌巴因(稀释在 9 g/L 的生理盐水(NaCl)中)来诱导实验性高血压,连续 21 天(n = 16)。结果结果表明,给高血压大鼠补充 1%的亚麻籽油能显著降低收缩压、舒张压和平均动脉压(P < 0.05),改善血浆和肝脏脂质状况,降低血浆中的葡萄糖水平。同样,亚麻籽油降低了血浆和组织中的 TBARS 水平以及心脏中的羰基水平。有趣的是,补充亚麻籽油能增加 GSH、硫醇和一氧化氮水平,改善组织中的 AchE 和抗氧化酶活性(SOD 和 GSH-Px)。
{"title":"Oil-extracted from flaxseeds protects against endothelial dysfunction and oxidative stress by modulating nitric oxide, thiols contents and improving redox status in ouabain-induced hypertensive rats","authors":"Sadia Berzou ,&nbsp;Fatima Zohra Labbaci ,&nbsp;Akila Guenzet ,&nbsp;Nawal Dida-Taleb ,&nbsp;Hakima Mir ,&nbsp;Djamil Krouf","doi":"10.1016/j.nupar.2024.02.003","DOIUrl":"10.1016/j.nupar.2024.02.003","url":null,"abstract":"<div><h3>Objectives</h3><p>The purpose of this study was to evaluate the antihypertensive and antioxidant effects of flaxseed oil in ouabain-induced hypertensive in normal rats Wistar.</p></div><div><h3>Methods</h3><p>Experimental hypertension was induced by a daily subcutaneous (sc) injection of 10<!--> <!-->μg/kg/day/rat of ouabain diluted in 9<!--> <!-->g/L of saline solution (NaCl) for 21 days (<em>n</em> <!-->=<!--> <!-->16). Animals were then divided into two groups fed an experimental diet containing 20% casein supplemented (Ouab-Oil-<em>Lu</em>) or not (Ouab) with 1% flaxseed oil whereas control rats (<em>n</em> <!-->=<!--> <!-->8) received only a daily sc injection of NaCl.</p></div><div><h3>Results</h3><p>The results showed that supplementing hypertensive rats with 1% flaxseed oil decreased significantly (<em>P</em> <!-->&lt;<!--> <!-->0.05) the systolic, diastolic, and mean arterial pressure, ameliorated plasma and liver lipid profile and reduced glucose levels in plasma. Similarly, flaxseed oil decreased TBARS levels in plasma and tissues, as well as carbonyl levels in the heart. Interestingly, this supplementation increased GSH, thiols and nitric oxide levels and improved AchE and antioxidant enzyme activities (SOD and GSH-Px) in the tissues.</p></div><div><h3>Conclusions</h3><p>Our findings suggested that flaxseed oil may provide a rationale for antihypertensive use in traditional medicine.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 2","pages":"Pages 120-128"},"PeriodicalIF":0.6,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving the prescriptive appropriateness of vitamin D: The Italian experience 提高维生素 D 的处方适当性:意大利的经验
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-04-09 DOI: 10.1016/j.nupar.2024.02.002
Francesco Ferrara , Andrea Zovi , Eduardo Nava , Ugo Trama , Roberto Langella

At the Asl Napoli 3 SUD a local, regional and national level analysis of prescription and spending related to the prescription and dispensing of drugs intended to increase vitamin D levels in the human body was carried out. The Italian Pharmacy Regulatory Agency (AIFA) in late 2019 introduced a prescriptive note of appropriateness (note 96) to regulate the prescribing activity of a drug that is widely used on the Italian national population, significantly affecting spending by the National Health System (NHS). Despite this action there has been an increase in prescription and expenditure of calcifediol at all levels of analysis (national, regional and local) while regarding the remaining Anatomical Therapeutic Chemical (ATC) referring to drugs used as vitamin D supplement in the Campania Region and at the Asl Napoli 3 SUD there is a slower decrease in expenditure and prescription, sometimes even increasing and in countertendency to the Italian national average. For these reasons, the Campania Region instituted two executive decrees (DD 405/2021 and 91/2022) that led to a marked reduction in spending and prescription in 2022 even higher than in other Italian regional realities. This analysis aims to show how vitamin D prescription is widespread and often inappropriate, attested by wide regional variability. In addition, the main recommendations for the use of these drugs are highlighted in order to raise awareness among all healthcare professionals of the informed use of these molecules ensuring sustainability and governance.

Asl Napoli 3 SUD 在地方、地区和国家层面对旨在提高人体维生素 D 水平的药物处方和配药相关的处方和支出进行了分析。意大利药房监管局(AIFA)于 2019 年末推出了一项适当性处方说明(96 号说明),以规范一种在意大利全国人口中广泛使用的药物的处方活动,这极大地影响了国家卫生系统(NHS)的支出。尽管采取了这一行动,但在各级分析(国家、地区和地方)中,降钙二酚的处方量和支出都有增加,而在坎帕尼亚大区和那不勒斯三区(Asl Napoli 3 SUD),其余用作维生素 D 补充剂的解剖治疗化学药物(ATC)的支出和处方量下降速度较慢,有时甚至会增加,并与意大利全国平均水平相反。由于这些原因,坎帕尼亚大区制定了两项行政法令(DD 405/2021 和 91/2022),导致 2022 年的支出和处方明显减少,甚至高于意大利其他大区的实际情况。本分析旨在说明维生素 D 的处方是如何普遍存在的,而且往往是不恰当的,各地区的差异很大就是证明。此外,还强调了使用这些药物的主要建议,以提高所有医疗保健专业人员对知情使用这些分子的认识,确保可持续性和治理。
{"title":"Improving the prescriptive appropriateness of vitamin D: The Italian experience","authors":"Francesco Ferrara ,&nbsp;Andrea Zovi ,&nbsp;Eduardo Nava ,&nbsp;Ugo Trama ,&nbsp;Roberto Langella","doi":"10.1016/j.nupar.2024.02.002","DOIUrl":"10.1016/j.nupar.2024.02.002","url":null,"abstract":"<div><p>At the Asl Napoli 3 SUD a local, regional and national level analysis of prescription and spending related to the prescription and dispensing of drugs intended to increase vitamin D levels in the human body was carried out. The Italian Pharmacy Regulatory Agency (AIFA) in late 2019 introduced a prescriptive note of appropriateness (note 96) to regulate the prescribing activity of a drug that is widely used on the Italian national population, significantly affecting spending by the National Health System (NHS). Despite this action there has been an increase in prescription and expenditure of calcifediol at all levels of analysis (national, regional and local) while regarding the remaining Anatomical Therapeutic Chemical (ATC) referring to drugs used as vitamin D supplement in the Campania Region and at the Asl Napoli 3 SUD there is a slower decrease in expenditure and prescription, sometimes even increasing and in countertendency to the Italian national average. For these reasons, the Campania Region instituted two executive decrees (DD 405/2021 and 91/2022) that led to a marked reduction in spending and prescription in 2022 even higher than in other Italian regional realities. This analysis aims to show how vitamin D prescription is widespread and often inappropriate, attested by wide regional variability. In addition, the main recommendations for the use of these drugs are highlighted in order to raise awareness among all healthcare professionals of the informed use of these molecules ensuring sustainability and governance.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 2","pages":"Pages 95-100"},"PeriodicalIF":0.6,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Le fardeau des aidants dans la nutrition artificielle à domicile 家庭人工营养给护理人员带来的负担
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/j.nupar.2023.12.001
Jean Castinel , Florian Poullenot

Non-professional caregivers provide assistance to patients losing their autonomy for some or all of the actions of daily life on a regular and frequent basis. Home artificial nutrition is a healthcare situation where the role of non-professional caregivers can be crucial. Non-professional caregiver burden, a concept initially developed for geriatrics, has been described and analyzed both among non-professional caregivers of enteral nutrition patients and, more recently, among those who support parenteral nutrition patients. In this article, we offer a literature review and an ethical perspective on this difficult social subject.

非专业护理人员经常定期为失去自主能力的病人提供部分或全部日常生活协助。家庭人工营养是一种医疗保健情况,在这种情况下,非专业护理人员的作用至关重要。非专业护理人员的负担这一概念最初是针对老年病学提出的,目前已对肠内营养患者的非专业护理人员以及最近对支持肠外营养患者的非专业护理人员进行了描述和分析。在本文中,我们将对这一棘手的社会问题进行文献综述并从伦理角度进行分析。
{"title":"Le fardeau des aidants dans la nutrition artificielle à domicile","authors":"Jean Castinel ,&nbsp;Florian Poullenot","doi":"10.1016/j.nupar.2023.12.001","DOIUrl":"10.1016/j.nupar.2023.12.001","url":null,"abstract":"<div><p>Non-professional caregivers provide assistance to patients losing their autonomy for some or all of the actions of daily life on a regular and frequent basis. Home artificial nutrition is a healthcare situation where the role of non-professional caregivers can be crucial. Non-professional caregiver burden, a concept initially developed for geriatrics, has been described and analyzed both among non-professional caregivers of enteral nutrition patients and, more recently, among those who support parenteral nutrition patients. In this article, we offer a literature review and an ethical perspective on this difficult social subject.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 1","pages":"Pages 11-15"},"PeriodicalIF":0.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139393786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxidative stress marker changes and cognitive decline prevention in Pb contaminated mice by Crocus sativus L. Supplementation and interval training 补充茜草和间歇训练可改变受铅污染小鼠的氧化应激标记和预防认知能力下降
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/j.nupar.2023.12.002
Sepideh Noruzi , Zohreh Meshkati , Rozita Nasiri

Heavy metals are contaminants hazardously affecting the animals’ and humans’ health since they are extensively utilized in the industry where proper physical activity and consuming antioxidant ingredients can be an appropriate solution for decreasing the resultant damages. This work deals with assessing the effects of Crocus sativus L. (saffron) petal extract (SPE) along with eight weeks of interval training on the cytotoxicity of lead (Pb) investigated in exposed adult male mice. SPE reduced the toxic effects of Pb that were indicated by the MTT assay. The morphological alterations of Pb-treated cells were found by fluorescent and normal microscopes when it was co-incubated with SPE. Accordingly, the 50% inhibitory concentration and the 50% lethal dose were calculated. The adult male mice were randomly placed into seven groups (six mice/group) of positive and negative controls, interval training group (Exr), Exr & Pb, SPE, SPE & Pb, and Exr & SPE & Pb treated groups. From the results, SPE did not affect catalase (CAT) activity, but it induced a significant increment of antioxidant enzyme SOD and the levels of malondialdehyde (MDA) is reduced remarkably in the brain. In the last part of the research, mice were exposed to the behavioral tasks examined by step-through ORT, MWM, and YM tests. Having interval training and SPE consumption could reverse the most defective behavioral indicators that may be protecting potential agents inspiringly to the Pb toxicity in the areas with higher heavy metals pollution.

重金属是危害动物和人类健康的污染物,因为它们被广泛应用于工业领域,而适当的体育锻炼和摄入抗氧化成分是减少由此造成的损害的适当解决方案。本研究评估了藏红花花瓣提取物(SPE)和八周间歇训练对成年雄性小鼠铅(Pb)细胞毒性的影响。通过 MTT 试验,SPE 降低了铅的毒性效应。用荧光显微镜和普通显微镜观察铅处理过的细胞,发现它们的形态发生了改变。据此计算出 50%的抑制浓度和 50%的致死剂量。将成年雄性小鼠随机分为七组(每组六只),分别为阳性对照组和阴性对照组、间歇训练组(Exr)、Exr & Pb组、SPE组、SPE & Pb组和Exr & SPE & Pb处理组。结果表明,SPE 不影响过氧化氢酶(CAT)的活性,但诱导了抗氧化酶 SOD 的显著增加,大脑中丙二醛(MDA)的水平明显降低。在研究的最后一部分,小鼠接受了通过步进式 ORT、MWM 和 YM 测试进行的行为任务检查。在重金属污染较严重的地区,间歇训练和摄入 SPE 可以逆转最有缺陷的行为指标,从而保护潜在的铅毒性启发剂。
{"title":"Oxidative stress marker changes and cognitive decline prevention in Pb contaminated mice by Crocus sativus L. Supplementation and interval training","authors":"Sepideh Noruzi ,&nbsp;Zohreh Meshkati ,&nbsp;Rozita Nasiri","doi":"10.1016/j.nupar.2023.12.002","DOIUrl":"10.1016/j.nupar.2023.12.002","url":null,"abstract":"<div><p>Heavy metals are contaminants hazardously affecting the animals’ and humans’ health since they are extensively utilized in the industry where proper physical activity and consuming antioxidant ingredients can be an appropriate solution for decreasing the resultant damages. This work deals with assessing the effects of <em>Crocus sativus</em> L. (saffron) petal extract (SPE) along with eight weeks of interval training on the cytotoxicity of lead (Pb) investigated in exposed adult male mice. SPE reduced the toxic effects of Pb that were indicated by the MTT assay. The morphological alterations of Pb-treated cells were found by fluorescent and normal microscopes when it was co-incubated with SPE. Accordingly, the 50% inhibitory concentration and the 50% lethal dose were calculated. The adult male mice were randomly placed into seven groups (six mice/group) of positive and negative controls, interval training group (Exr), Exr &amp; Pb, SPE, SPE &amp; Pb, and Exr &amp; SPE &amp; Pb treated groups. From the results, SPE did not affect catalase (CAT) activity, but it induced a significant increment of antioxidant enzyme SOD and the levels of malondialdehyde (MDA) is reduced remarkably in the brain. In the last part of the research, mice were exposed to the behavioral tasks examined by step-through ORT, MWM, and YM tests. Having interval training and SPE consumption could reverse the most defective behavioral indicators that may be protecting potential agents inspiringly to the Pb toxicity in the areas with higher heavy metals pollution.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 1","pages":"Pages 44-55"},"PeriodicalIF":0.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139888338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of coffee consumption with atherosclerotic cardiovascular disease and all-cause mortality in adults with familial hypercholesterolemia: Results from National Health and Nutrition Examination Survey (NHANES) 家族性高胆固醇血症成人饮用咖啡与动脉粥样硬化性心血管疾病和全因死亡率的关系:美国国家健康与营养调查(NHANES)的结果
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/j.nupar.2023.10.002
Jun Wen , Lei-Lei Du , Qi Pan , Jing-Jing Song , Yu-Peng Liu , Xiang-Bin Meng , Kuo Zhang , Jun Gao , Chun-Li Shao , Wen-Yao Wang , Hao Zhou , Yi-Da Tang

Objective

Familial hypercholesterolemia (FH) is a common inherited metabolic disorder with an elevated risk of atherosclerotic cardiovascular disease (ASCVD). The effects of coffee on FH individuals remain unclear. The aim of this study is to examine the association between coffee consumption and ASCVD and mortality in adults with clinical diagnosed FH.

Material and methods

Cross-sectional and prospective (up to December 31st, 2019) analysis of National Health and Nutrition Examination Survey (NHANES) 1999–2018. Coffee consumption was calculated by 24-hour dietary recalls. Multivariable-adjusted logistic regression and Cox analysis were performed to evaluated the relationship between coffee consumption and ASCVD and all-cause mortality.

Results

A total of 1008 FH individuals with coffee information were included and were categorized into four groups: 357 (35.42%) did not consume coffee on a regular basis, 390 (38.69%) consumed 0.5–3 cups per day, 141 (13.99%) consumed 3–5 cups per day and 120 (11.90%) ≥5 cups per day. Higher coffee or caffeine consumption was associated with elevated risk of ASCVD and heart attack. Compared to non-coffee drinkers, ≥5 cups coffee drinking was associated with higher risk of all-cause mortality (multivariate HR: 1.67, 95%CI: 1.02–2.73, P = 0.04). The risk of all-cause death increased dose-dependently along with the higher coffee or caffeine intake (P < 0.05). The results remained similar among those who excluded non-coffee drinkers.

Conclusion

Coffee consumption of up to five cups per day was associated with unfavorable ASCVD and all-cause mortality, suggesting that high coffee consumption should be avoided among patients with FH.

目的家族性高胆固醇血症(FH)是一种常见的遗传代谢性疾病,其罹患动脉粥样硬化性心血管疾病(ASCVD)的风险较高。咖啡对家族性高胆固醇血症患者的影响尚不清楚。本研究旨在探讨临床诊断为 FH 的成年人饮用咖啡与 ASCVD 和死亡率之间的关系。材料与方法对 1999-2018 年美国国家健康与营养调查(NHANES)进行横断面和前瞻性分析(截至 2019 年 12 月 31 日)。咖啡消耗量通过 24 小时膳食回忆进行计算。结果 共纳入1008名有咖啡信息的FH患者,并将其分为四组:357人(35.42%)不经常喝咖啡,390人(38.69%)每天喝0.5-3杯,141人(13.99%)每天喝3-5杯,120人(11.90%)每天≥5杯。较高的咖啡或咖啡因摄入量与急性心肌梗死和心脏病发作风险升高有关。与不喝咖啡的人相比,喝咖啡≥5 杯的人全因死亡风险更高(多变量 HR:1.67,95%CI:1.02-2.73,P = 0.04)。随着咖啡或咖啡因摄入量的增加,全因死亡风险也呈剂量依赖性增加(P < 0.05)。结论:每天饮用多达五杯咖啡与不利的ASCVD和全因死亡有关,这表明FH患者应避免大量饮用咖啡。
{"title":"Association of coffee consumption with atherosclerotic cardiovascular disease and all-cause mortality in adults with familial hypercholesterolemia: Results from National Health and Nutrition Examination Survey (NHANES)","authors":"Jun Wen ,&nbsp;Lei-Lei Du ,&nbsp;Qi Pan ,&nbsp;Jing-Jing Song ,&nbsp;Yu-Peng Liu ,&nbsp;Xiang-Bin Meng ,&nbsp;Kuo Zhang ,&nbsp;Jun Gao ,&nbsp;Chun-Li Shao ,&nbsp;Wen-Yao Wang ,&nbsp;Hao Zhou ,&nbsp;Yi-Da Tang","doi":"10.1016/j.nupar.2023.10.002","DOIUrl":"https://doi.org/10.1016/j.nupar.2023.10.002","url":null,"abstract":"<div><h3>Objective</h3><p>Familial hypercholesterolemia (FH) is a common inherited metabolic disorder with an elevated risk of atherosclerotic cardiovascular disease (ASCVD). The effects of coffee on FH individuals remain unclear. The aim of this study is to examine the association between coffee consumption and ASCVD and mortality in adults with clinical diagnosed FH.</p></div><div><h3>Material and methods</h3><p>Cross-sectional and prospective (up to December 31st, 2019) analysis of National Health and Nutrition Examination Survey (NHANES) 1999–2018. Coffee consumption was calculated by 24-hour dietary recalls. Multivariable-adjusted logistic regression and Cox analysis were performed to evaluated the relationship between coffee consumption and ASCVD and all-cause mortality.</p></div><div><h3>Results</h3><p>A total of 1008 FH individuals with coffee information were included and were categorized into four groups: 357 (35.42%) did not consume coffee on a regular basis, 390 (38.69%) consumed 0.5–3 cups per day, 141 (13.99%) consumed 3–5 cups per day and 120 (11.90%) ≥5 cups per day. Higher coffee or caffeine consumption was associated with elevated risk of ASCVD and heart attack. Compared to non-coffee drinkers, ≥5 cups coffee drinking was associated with higher risk of all-cause mortality (multivariate HR: 1.67, 95%CI: 1.02–2.73, <em>P</em> <!-->=<!--> <!-->0.04). The risk of all-cause death increased dose-dependently along with the higher coffee or caffeine intake (<em>P</em> <!-->&lt;<!--> <!-->0.05). The results remained similar among those who excluded non-coffee drinkers.</p></div><div><h3>Conclusion</h3><p>Coffee consumption of up to five cups per day was associated with unfavorable ASCVD and all-cause mortality, suggesting that high coffee consumption should be avoided among patients with FH.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 1","pages":"Pages 27-35"},"PeriodicalIF":0.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0985056223002820/pdfft?md5=01df0d63c79f2d489f5b740a70e9824e&pid=1-s2.0-S0985056223002820-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139992379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Issue contents 议题内容
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/S0985-0562(24)00057-8
{"title":"Issue contents","authors":"","doi":"10.1016/S0985-0562(24)00057-8","DOIUrl":"https://doi.org/10.1016/S0985-0562(24)00057-8","url":null,"abstract":"","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 1","pages":"Page e1"},"PeriodicalIF":0.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0985056224000578/pdfft?md5=5032a4b96cf69fa0c042a7ee5910acca&pid=1-s2.0-S0985056224000578-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139992669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute changes in serum inflammatory signatures after consumption of ready-to-drink immuno-nutrition: A case report 饮用即饮免疫营养品后血清炎症特征的急性变化:病例报告
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/j.nupar.2024.01.001
Matteo Briguglio , Enrico Ragni , Francesco Langella , Laura Scaramuzzo , Tiziano Crespi , Thomas W. Wainwright , Giuseppe Banfi , Pedro Berjano

Background

Immuno-nutrition administers specific nutrients to improve host defences, in particular supporting the immune system. Given the high invasiveness of some spine operations, strengthening the immune response could effectively balance the surgical stress and boost resilience. However, it is not clear what are the early molecular signatures after the consumption of immuno-modulatory nutrients.

Materials and methods

In the context of nutritional prehabilitation, we present the case of a lady with scoliosis scheduled for surgery who was administered immuno-nutrition preoperatively and tested for acute changes in 200 biomolecules after two and four hours.

Results

After four hours, we mainly observed 30-fold increase in IL-10, 10-fold increase in IL-18 inhibitory protein, 6-fold increase in IL-1 inhibitory receptor, 12-fold decrease in IL-2 receptor, and 51-fold decrease in IL-23. Gene ontology annotations showed the involvement of genes regulating cytokine activity, response to external organisms, humoral and adaptive response, and lymphocyte immunity.

Conclusion

Overall, the trends over the first four hours showed a positive shift of the cytokine balance in favour of anti-inflammatory mediators while keeping active the cell-mediated immunity. The use of immuno-nutrition for prehabilitation patients could prove useful to patients but benefits from chronic consumption and surgical outcomes remain to be determined.

背景免疫营养通过提供特定的营养物质来提高宿主的防御能力,特别是支持免疫系统。鉴于某些脊柱手术的侵袭性较高,加强免疫反应可有效平衡手术压力并提高恢复能力。材料和方法在营养预康复的背景下,我们介绍了一位计划接受手术的脊柱侧弯女士的病例,她在术前接受了免疫营养治疗,并在两小时和四小时后检测了 200 种生物分子的急性变化。结果四小时后,我们主要观察到 IL-10 增加了 30 倍,IL-18 抑制蛋白增加了 10 倍,IL-1 抑制受体增加了 6 倍,IL-2 受体减少了 12 倍,IL-23 减少了 51 倍。基因本体注释显示,调节细胞因子活性、对外部有机体的反应、体液和适应性反应以及淋巴细胞免疫的基因参与其中。对康复前病人使用免疫营养可能对病人有用,但长期使用的益处和手术效果仍有待确定。
{"title":"Acute changes in serum inflammatory signatures after consumption of ready-to-drink immuno-nutrition: A case report","authors":"Matteo Briguglio ,&nbsp;Enrico Ragni ,&nbsp;Francesco Langella ,&nbsp;Laura Scaramuzzo ,&nbsp;Tiziano Crespi ,&nbsp;Thomas W. Wainwright ,&nbsp;Giuseppe Banfi ,&nbsp;Pedro Berjano","doi":"10.1016/j.nupar.2024.01.001","DOIUrl":"10.1016/j.nupar.2024.01.001","url":null,"abstract":"<div><h3>Background</h3><p>Immuno-nutrition administers specific nutrients to improve host defences, in particular supporting the immune system. Given the high invasiveness of some spine operations, strengthening the immune response could effectively balance the surgical stress and boost resilience. However, it is not clear what are the early molecular signatures after the consumption of immuno-modulatory nutrients.</p></div><div><h3>Materials and methods</h3><p>In the context of nutritional prehabilitation, we present the case of a lady with scoliosis scheduled for surgery who was administered immuno-nutrition preoperatively and tested for acute changes in 200 biomolecules after two and four hours.</p></div><div><h3>Results</h3><p>After four hours, we mainly observed 30-fold increase in IL-10, 10-fold increase in IL-18 inhibitory protein, 6-fold increase in IL-1 inhibitory receptor, 12-fold decrease in IL-2 receptor, and 51-fold decrease in IL-23. Gene ontology annotations showed the involvement of genes regulating cytokine activity, response to external organisms, humoral and adaptive response, and lymphocyte immunity.</p></div><div><h3>Conclusion</h3><p>Overall, the trends over the first four hours showed a positive shift of the cytokine balance in favour of anti-inflammatory mediators while keeping active the cell-mediated immunity. The use of immuno-nutrition for prehabilitation patients could prove useful to patients but benefits from chronic consumption and surgical outcomes remain to be determined.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 1","pages":"Pages 56-66"},"PeriodicalIF":0.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139875017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
La malnutrition aiguë sévère : de la physiopathologie à la prise en charge 严重急性营养不良:从病理生理学到管理
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/j.nupar.2023.11.003
Adrien Noel , Fanny B. Morel , Rachel Marion-Letellier

Undernutrition is a major global health issue. In 2022, acute malnutrition affected 45 million children under the age of five, including at least 13.6 million in severe acute malnutrition (SAM). Acutely malnourished children have a high risk of mortality, of staturo-ponderal growth retardation and of co-morbidities such as diarrhea. They can also present cognitive and metabolic disorders in adulthood. SAM includes nutritional edema (kwashiorkor) and severe wasting. Management of SAM is based on the guidelines of the World Health Organization (WHO), updated in 2023. Diagnostic is performed through clinical exam and anthropometric criteria, as middle-upper arm circumference or weight-for-age z-score. Ready-to-use therapeutic food (RUTF) are used to treat children aged 6–59 months up to recovery. Nowadays, a particular focus on improving recovery and coverage is performed, notably through integrated/simplified protocols, formulation of alternative RUTFs or anticipation of risks of relapse for SAM children. Finally, the prevention of SAM, which is now included in WHO's guidelines, deserves greater attention by, for example, targeting nutrition of children of 6–59 months and/or nutritional quality of pregnant and lactating women.

营养不良是一个重大的全球健康问题。2022 年,4,500 万五岁以下儿童受到急性营养不良的影响,其中至少有 1,360 万儿童患有严重急性营养不良。急性营养不良的儿童死亡率高、体格发育迟缓和合并疾病(如腹泻)的风险高。他们成年后还可能出现认知和代谢紊乱。SAM 包括营养性水肿(kwashiorkor)和严重消瘦。萨姆病的管理以世界卫生组织(WHO)2023 年更新的指南为基础。诊断通过临床检查和人体测量标准(如中上臂围或年龄体重 Z 值)进行。即食食疗食品(RUTF)用于治疗 6-59 个月至康复期的儿童。目前,特别注重提高康复率和覆盖率,尤其是通过综合/简化方案、配制替代性即食食疗食品或预测萨姆病儿童复发的风险。最后,预防 SAM 现已被纳入世卫组织的指导方针,应通过针对 6-59 个月儿童的营养和/或孕妇和哺乳期妇女的营养质量等方式给予更多关注。
{"title":"La malnutrition aiguë sévère : de la physiopathologie à la prise en charge","authors":"Adrien Noel ,&nbsp;Fanny B. Morel ,&nbsp;Rachel Marion-Letellier","doi":"10.1016/j.nupar.2023.11.003","DOIUrl":"10.1016/j.nupar.2023.11.003","url":null,"abstract":"<div><p>Undernutrition is a major global health issue. In 2022, acute malnutrition affected 45 million children under the age of five, including at least 13.6 million in severe acute malnutrition (SAM). Acutely malnourished children have a high risk of mortality, of staturo-ponderal growth retardation and of co-morbidities such as diarrhea. They can also present cognitive and metabolic disorders in adulthood. SAM includes nutritional edema (<em>kwashiorkor</em>) and severe wasting. Management of SAM is based on the guidelines of the World Health Organization (WHO), updated in 2023. Diagnostic is performed through clinical exam and anthropometric criteria, as middle-upper arm circumference or weight-for-age z-score. Ready-to-use therapeutic food (RUTF) are used to treat children aged 6–59 months up to recovery. Nowadays, a particular focus on improving recovery and coverage is performed, notably through integrated/simplified protocols, formulation of alternative RUTFs or anticipation of risks of relapse for SAM children. Finally, the prevention of SAM, which is now included in WHO's guidelines, deserves greater attention by, for example, targeting nutrition of children of 6–59 months and<em>/</em>or nutritional quality of pregnant and lactating women.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 1","pages":"Pages 2-10"},"PeriodicalIF":0.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139394699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum zonulin level as a novel approach in diagnosis and follow-up of patients with celiac disease. A systematic review and meta-analysis 血清 zonulin 水平作为诊断和随访乳糜泻患者的一种新方法。系统回顾和荟萃分析
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/j.nupar.2023.11.002
Reyhaneh Rabiee , Reza Mahdavi , Zeinab Nikniaz

Background

It has been proposed that zonulin, a tight junction protein regulator, is involved in the pathogenesis of celiac disease (CD). In this regard, various studies compared the mean serum zonulin in patients with CD and healthy controls. However, this remains a subject of controversy due to contradictory results. Therefore, the goal of the present study was to summarize the findings of studies comparing CD patients’ serum zonulin levels to healthy controls.

Methods

We searched PubMed, Scopus, and ISI Web of Science databases up to May 2022. All observational studies measured serum zonulin in adult patients with CD and healthy controls were included without language or date restrictions. The standardized mean differences (SMDs) and standard deviations were pooled using a random-effects model.

Results

Of 708 studies, six studies with 184 CD and 206 control participants were included in the systematic review and meta-analysis. According to a pooled analysis, CD patients had significantly higher zonulin levels than healthy controls (SMD = 1.08 ng/mL; 95% CI = 0.64, 1.52; P < 0.001). Subgroup analyses were performed according to adherence to a gluten-free diet (GFD), zonulin assessment method, and CD diagnosis. The significant effect was maintained in all subgroups.

Conclusion

CD is significantly correlated with a higher level of serum zonulin. Thus, zonulin could be a potential biomarker for the diagnosis of CD, which deserves further investigation.

背景有研究认为,zonulin 是一种紧密连接蛋白调节因子,与乳糜泻(CD)的发病机制有关。在这方面,多项研究比较了 CD 患者和健康对照组的平均血清 zonulin。然而,由于结果相互矛盾,这仍然是一个有争议的话题。因此,本研究的目的是总结比较 CD 患者与健康对照组血清zonulin 水平的研究结果。方法我们检索了截至 2022 年 5 月的 PubMed、Scopus 和 ISI Web of Science 数据库。所有测量成年 CD 患者和健康对照组血清佐宁球蛋白的观察性研究均被纳入,无语言和日期限制。结果 在 708 项研究中,有 6 项研究纳入了系统综述和荟萃分析,其中包括 184 名 CD 患者和 206 名对照组患者。根据汇总分析,CD患者的zonulin水平明显高于健康对照组(SMD = 1.08 ng/mL; 95% CI = 0.64, 1.52; P < 0.001)。根据是否坚持无麸质饮食(GFD)、佐宁评估方法和 CD 诊断进行了分组分析。结论 CD 与较高的血清 zonulin 水平明显相关。因此,zonulin 可能是诊断 CD 的潜在生物标志物,值得进一步研究。
{"title":"Serum zonulin level as a novel approach in diagnosis and follow-up of patients with celiac disease. A systematic review and meta-analysis","authors":"Reyhaneh Rabiee ,&nbsp;Reza Mahdavi ,&nbsp;Zeinab Nikniaz","doi":"10.1016/j.nupar.2023.11.002","DOIUrl":"10.1016/j.nupar.2023.11.002","url":null,"abstract":"<div><h3>Background</h3><p><span>It has been proposed that zonulin, a tight junction protein<span> regulator, is involved in the pathogenesis of celiac disease (CD). In this regard, various studies compared the mean serum zonulin </span></span>in patients with CD and healthy controls. However, this remains a subject of controversy due to contradictory results. Therefore, the goal of the present study was to summarize the findings of studies comparing CD patients’ serum zonulin levels to healthy controls.</p></div><div><h3>Methods</h3><p>We searched PubMed, Scopus, and ISI Web of Science databases up to May 2022. All observational studies measured serum zonulin in adult patients with CD and healthy controls were included without language or date restrictions. The standardized mean differences (SMDs) and standard deviations were pooled using a random-effects model.</p></div><div><h3>Results</h3><p><span>Of 708 studies, six studies with 184 CD and 206 control participants were included in the systematic review and meta-analysis. According to a pooled analysis, CD patients had significantly higher zonulin levels than healthy controls (SMD</span> <!-->=<!--> <!-->1.08<!--> <!-->ng/mL; 95% CI<!--> <!-->=<!--> <!-->0.64, 1.52; <em>P</em> <!-->&lt;<!--> <span>0.001). Subgroup analyses were performed according to adherence to a gluten-free diet (GFD), zonulin assessment method, and CD diagnosis. The significant effect was maintained in all subgroups.</span></p></div><div><h3>Conclusion</h3><p>CD is significantly correlated with a higher level of serum zonulin. Thus, zonulin could be a potential biomarker for the diagnosis of CD, which deserves further investigation.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"38 1","pages":"Pages 36-43"},"PeriodicalIF":0.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139395683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Nutrition Clinique et Metabolisme
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1