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A review of haptics in dental surgery 口腔外科触觉学研究进展综述
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_173_22
J. Ramachandra, S. Siddaiah, Somya Sinha
Dentistry is a professional field, and patients receive dental care in a straightforward way owing to the use of tactile abilities. Haptics act of identifying things through touch. It is an innovation in both medical and dentistry procedures. The current revelations have proposed that haptic and virtual technologies might improve dentistry education outcomes, and scientific data have supported the use of virtual technology in dentistry. With the utilization of haptics, students can acquire skills without putting a strain on resources or labor by obtaining access to an unlimited number of training hours. This review offers a succinct overview of the haptics literature for educating dental students.
牙科是一个专业领域,由于触觉能力的使用,患者可以直接接受牙科护理。触觉通过触摸识别事物的行为。这是医学和牙科程序的创新。目前的披露表明,触觉和虚拟技术可能会改善牙科教育成果,科学数据支持虚拟技术在牙科中的使用。通过使用触觉,学生可以通过获得无限数量的培训时间来获得技能,而不会给资源或劳动力带来压力。这篇综述提供了一个简明的综述触觉文学教育牙科学生。
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引用次数: 0
Treatment response and short-term outcomes in children admitted as multisystem inflammatory syndrome in children 儿童多系统炎症综合征的治疗反应和短期预后
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_210_22
M. Batt, G. Saini, M. Dar
Background: Multisystem inflammatory syndrome in children (MIS-C) is a postviral complication that has been described among children after 2–6 weeks of exposure to the COVID-19 virus from various parts of the world. Published literature regarding MIS-C in children is limited. The aim of this study was to investigate the disease management and clinical outcomes of a larger group of children from North India presenting with features of MIS-C. Materials and Methods: This is an observational study of children with MIS-C, admitted to the pediatric intensive care unit (PICU) between March 1, 2021, and August 31, 2021, during the second wave of SARS-CoV-2 infection in India. Results: Out of the 37 children presenting with MIS-C, 62% of patients were male and 37% were female patients. Vasoactive medications were required in 14 patients. Eighteen patients required respiratory support, of which 17 received noninvasive ventilation and only one patient required invasive mechanical ventilation. Methylprednisolone and intravenous immunoglobulin (IVIG) were used in the majority of patients. No patient required remdesivir. Thirty-six patients were discharged home with a median duration of 4 days in PICU and a hospital stay of 10 days, only 1 (2.7%) patient died during the treatment. Thirty-five (94.5%) patients received IVIG alone, and five patients (13.5%) received IVIG along with methylprednisolone. Patients who received a combination of steroids and IVIG had greater severity of illness, deranged laboratory parameters, highly raised inflammatory markers, requiring higher inotropes, respiratory support, PICU requirement, and length of stay in hospital. Conclusions: The decision to treat MIS-C patients with IVIG plus methylprednisolone or IVIG alone must be reviewed on an individual basis. IVIG in conjunction with methylprednisolone should be considered for patients with severe MIS-C and hypotension who have been admitted to the PICU.
背景:儿童多系统炎症综合征(MIS-C)是一种病毒后并发症,已在世界各地接触新冠肺炎病毒2-6周后的儿童中进行了描述。已发表的关于儿童MIS-C的文献有限。本研究的目的是调查来自北印度的一大群具有MIS-C特征的儿童的疾病管理和临床结果。材料和方法:这是一项针对2021年3月1日至2021年8月31日期间在印度第二波严重急性呼吸系统综合征冠状病毒2型感染期间入住儿科重症监护室(PICU)的MIS-C儿童的观察性研究。结果:在37名出现MIS-C的儿童中,62%的患者为男性,37%为女性。14名患者需要使用血管活性药物。18名患者需要呼吸支持,其中17名患者接受了无创通气,只有一名患者需要有创机械通气。大多数患者使用甲基泼尼松和静脉注射免疫球蛋白(IVIG)。没有患者需要瑞德西韦。36名患者出院回家,在PICU的中位持续时间为4天,住院时间为10天,只有1名(2.7%)患者在治疗期间死亡。35名(94.5%)患者单独接受IVIG治疗,5名(13.5%)患者接受IVIG和甲基强的松龙治疗。接受类固醇和IVIG联合治疗的患者病情更严重,实验室参数紊乱,炎症标志物高度升高,需要更高的止痛药、呼吸支持、PICU要求和住院时间。结论:使用IVIG联合甲基强的松龙或单独使用IVIG治疗MIS-C患者的决定必须根据个人情况进行审查。对于已入住PICU的严重MIS-C和低血压患者,应考虑IVIG联合甲基强的松龙。
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引用次数: 0
Perception of 2nd-Year medical undergraduates regarding the implementation of competency-Based medical education in pharmacology 药理学专业二年级本科生对实施能力本位医学教育的看法
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_224_22
Vidya M. Mahalmani, N. Hashilkar, A. Hogade, Netravathi Basavaraj
Objectives: The purpose of the study was to understand the perception of 2nd-year medical undergraduates regarding the implementation of competency-based medical education (CBME) in pharmacology. Materials and Methods: This cross-sectional study was undertaken by the department of pharmacology, in our institution. Out of 197 s year medical undergraduate students, 192 provided their valuable feedback. The questionnaire consisted of three types of questions: (1) multiple-choice questions, (2) rating on a 5-point Likert scale, and (3) open-ended questions. In the open-ended questions, the students were asked to share their views. Responses to the questions were recorded. Students' “feedback responses” were scrutinized in terms of percentages. Conceptual content analysis was done for open-ended questions. Results: Students were satisfied with the implementation of CBME as well as the conduct of small group teaching, self-directed learning, integrated assessment, attitude, ethics, and communication skills, and pandemic modules. They emphasized more on game-based learning and other innovative teaching–learning methods that drove their interest to understand the subject better. Conclusion: Implementation of CBME has been found to be more effective than the traditional didactic approach.
目的:本研究旨在了解医学二年级本科生对实施药理学能力本位医学教育(CBME)的看法。材料和方法:这项横断面研究由我们机构的药理学系进行。在197名医学本科生中,192人提供了宝贵的反馈。问卷由三种类型的问题组成:(1)多项选择题,(2)5分Likert量表评分,(3)开放式问题。在开放式问题中,学生们被要求分享他们的观点。对问题的答复被记录下来。学生的“反馈反应”以百分比的形式被仔细审查。对开放式问题进行了概念内容分析。结果:学生对CBME的实施以及小组教学、自主学习、综合评估、态度、道德和沟通技能以及流行病模块的实施感到满意。他们更多地强调基于游戏的学习和其他创新的教学方法,这些方法激发了他们更好地理解学科的兴趣。结论:实施CBME比传统的教学方法更有效。
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引用次数: 0
Post-Coronavirus disease 2019 condition 2019冠状病毒后疾病状态
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_237_23
R. Nerli, S. Rangrez
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引用次数: 0
Aldehyde dehydrogenase isoform 1 as an indicator in the malignant potential of cutaneous lichen planus 醛脱氢酶异构体1在皮肤扁平苔藓恶性潜能中的指示作用
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_62_22
F. Aliakbarpour, Robabeh Alijanpour, R. Ghorbani, Saba Bisheh, Arezoo Kashfi, Shabnam Sohanian
Introduction: Hypertrophic variant of cutaneous lichen planus (CLP) is a chronic variant with controversial malignant association. Since aldehyde dehydrogenase isoform 1 (ALDH1) is considered as a prognostic marker in various cancers and its expression was significantly associated with malignant transformation in the oral type of lichen planus. So we decided to assess the ALDH1 expression in CLP in order to know the role of this biomarker in the CLP. Materials and Methods: Thirty blocks of CLP from the archive of Dermatology Department of Babol University of Medical Sciences and 30 blocks of normal skin as the control group were selected. Immunohistochemical staining for ALDH1 marker was performed. In terms of evaluation of the ALDH1 expression, the percentage of stained cells as well as the intensity of cytoplasmic staining was considered. Results: In this study, the percentage of stained cells, the intensity of staining the epidermal cells, and the final score of the ALDH-1 expression were significantly different between two groups (P < 0.001). There was no significant relationship between ALDH-1 expressions and sex (P = 0.0202), and also, lesion location and final score (P = 0.345). No correlation was found between age and ALDH-1 expression (P = 0.217, r = 0.232). Conclusion: To sum up, ALDH1 was significantly expressed in CLP; furthermore, the expression may be correlated with malignant transformation. Consequently, ALDH1 might be an independent prognostic indicator in CLP. However, further studies with larger patient samples are required to verify the findings of the current study.
简介:皮肤扁平苔藓(CLP)的肥大性变体是一种有争议的恶性关联的慢性变体。由于醛脱氢酶亚型1(ALDH1)被认为是各种癌症的预后标志物,并且其表达与口腔型扁平苔藓的恶性转化显著相关。因此,我们决定评估CLP中ALDH1的表达,以了解该生物标志物在CLP中的作用。材料与方法:选用巴勃尔医科大学皮肤科档案馆CLP 30块,正常皮肤30块作为对照组。对ALDH1标记物进行免疫组织化学染色。在评估ALDH1表达方面,考虑了染色细胞的百分比以及细胞质染色的强度。结果:在本研究中,两组染色细胞的百分比、表皮细胞的染色强度和ALDH-1表达的最终评分有显著差异(P<0.001)。ALDH-1的表达与性别无显著关系(P=0.0202),病变位置和最终评分(P=0.345)。年龄与ALDH-1表达之间没有相关性(P=0.217,r=0.232)。结论:总之,ALDH1在CLP中显著表达;此外,该表达可能与恶性转化有关。因此,ALDH1可能是CLP的独立预后指标。然而,需要对更大的患者样本进行进一步研究,以验证当前研究的结果。
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引用次数: 0
Identification and management of Snake Bite in Asia: A narrative review 亚洲地区蛇咬伤的鉴定与管理:述评
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_92_22
M. Rathinasamy, M. Mithuna, S. Ramasamy, Jane Antony, V. Jaishree, M. Alexander
Snake bites are an important cause of illness and deaths in the rural population in tropical, subtropical and southeast Asian countries. There are more than 3000 species of snakes found all over the world of which around 300 species are found in India. In India, most of snake bite deaths occur due to delayed arrival to treatment centers. The purpose of the present review article is to explore the various species of snakes, their toxicology, clinical manifestations, and management. In addition, various ways to avoid snake bites and early approaches to government centers rather than private centers for the availability of Anti-snake venom have been discussed in this article. Rapid diagnostic test for the identification of species is available in selective centers only and treatment mainly depends on the administration of anti-snake venom. In addition, proper community education and strong health-care policy will reduce the morbidity and mortality due to snake bites.
蛇咬伤是热带、亚热带和东南亚国家农村人口患病和死亡的重要原因。世界各地发现的蛇有3000多种,其中约300种在印度发现。在印度,大多数被蛇咬致死的原因是延迟到达治疗中心。这篇综述文章的目的是探讨各种蛇,它们的毒理学,临床表现和管理。此外,本文还讨论了避免被蛇咬伤的各种方法,以及早期向政府中心而非私人中心提供抗蛇毒的方法。鉴定物种的快速诊断测试只能在选择性中心进行,治疗主要取决于抗蛇毒的给药。此外,适当的社区教育和强有力的卫生保健政策将降低因蛇咬伤而导致的发病率和死亡率。
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引用次数: 0
Melasma-like hyperpigmentation: A rare side effect of imatinib mesylate 黄褐斑样色素沉着:甲磺酸伊马替尼的罕见副作用
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_225_22
S. Agrawal, Bhushan Madke, Sugat A Jawade, A. Singh
Imatinib mesylate is an oral tyrosine kinase inhibitor used chiefly to treat chronic myeloid leukemia. In the literature, hypopigmentation is a commonly reported side effect of imatinib therapy; however, the cases of melasma-like hyperpigmentation due to imatinib have also been sparingly reported. We report a 35-year-old male patient who had asymptomatic hyperpigmentation over the cheeks and nose for 3 months after being started with oral imatinib. Examination showed pigmentation confined to the cheeks and nose. The diagnosis was made clinically along with dermoscopy, and the patient was treated with conventional skin-lightening regimen and sunscreen.
甲磺酸伊马替尼是一种口服酪氨酸激酶抑制剂,主要用于治疗慢性髓性白血病。在文献中,低色素沉着是伊马替尼治疗的常见副作用;然而,伊马替尼引起的黄褐斑样色素沉着的病例也很少报道。我们报告了一位35岁的男性患者,他在开始口服伊马替尼3个月后,脸颊和鼻子无症状色素沉着。检查显示色素沉着局限于脸颊和鼻子。临床诊断并行皮肤镜检查,患者接受常规美白方案及防晒霜治疗。
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引用次数: 0
A case report on smear-Positive pulmonary tuberculosis with neurofibromatosis type-1 涂阳肺结核合并1型神经纤维瘤病1例报告
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_191_22
Khushboo Chavda, S. Mistry, C. Sajan
Neurofibromatosis (NF) is a group of disorders that is caused by a genetic mutation which is dominantly inherited neurogenetic disorder. They are of three types: NF1, NF2, and schwannomatosis. Out of these three, NF1 is the most common. NF1 mainly affects the skin, peripheral and central nervous system, bones, cardiovascular, and endocrine systems. Tuberculosis is a bacterial infection of the lung that is caused by Mycobacterium tuberculosis. It spreads by speaking, sneezing, and coughing in the air. Active pulmonary infections can spread to other people. Here, we represent a case of a 45-year-old male diagnosed with pulmonary tuberculosis (PTB) presenting with breathlessness, fever, loss of appetite, runny nose, nervousness, and dry cough. The patient had multiple swellings over the body with papules and nodules seen on different parts of the body. Cafe-au-lait macules were also present. After the all-over examination, the patient was diagnosed with smear-positive PTB with NF1.
神经纤维瘤病(NF)是一组由基因突变引起的疾病,主要是遗传性神经遗传疾病。它们有三种类型:NF1、NF2和神经鞘瘤病。在这三种类型中,NF1是最常见的。NF1主要影响皮肤、周围和中枢神经系统、骨骼、心血管和内分泌系统。结核病是一种由结核分枝杆菌引起的肺部细菌感染。它通过说话、打喷嚏和咳嗽在空气中传播。活动性肺部感染可以传播给其他人。在此,我们报告一例45岁男性肺结核(PTB),表现为呼吸困难、发烧、食欲不振、流鼻涕、紧张和干咳。患者全身多处肿胀,不同部位可见丘疹和结节。此外,还发现了咖啡黑斑。经全身检查,诊断为痰阳性结核伴NF1。
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引用次数: 0
Study of bone marrow iron storage in patients presented with pancytopenia 全血细胞减少患者骨髓铁储存的研究
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_188_22
P. Bardapurkar, Ruchi Randive, Sushama Gurwale, C. Gore, V. Viswanathan
Introduction: Bone marrow examination is a useful technique for the evaluation of both hematological and nonhematological diseases. Perls Prussian blue stain is the “gold standard” to demonstrate the iron content and hemosiderin in the sideroblasts and the bone marrow macrophages. In our study, we assess the grades of iron storage in the bone marrow, as seen in various diseases in pancytopenia patients. Materials and Methods: An evaluation of iron storage in bone marrow aspirate of 140 patients of pancytopenia in a tertiary care center in western India, using Perls' stain and Gales' system of grading. Results: Out of all pancytopenia cases, 60.71% of the cases had low iron stores, 30% had normal, and 9.29% of cases had high iron stores, using Gales' system of iron stores grading. Dimorphic anemia was in the range of 0–3 iron store grade, with 72.4% having low iron stores, 24.6% having normal iron stores, and 2.8% having high iron stores. Megaloblastic anemia showed iron store grade in the range of 0–4, and iron-deficiency anemia showed decreased iron stores, along with multiple myeloma, acute lymphoblastic leukemia, and aplastic anemia. Conclusion: Gale's method of grading is used universally to grade iron stores in bone marrow aspirate as it is highly convenient and result oriented and it helps clinicians to plan necessary treatment accordingly.
骨髓检查是评估血液和非血液疾病的一项有用技术。珀尔斯普鲁士蓝染色是显示铁母细胞和骨髓巨噬细胞中铁含量和含铁血黄素的“金标准”。在我们的研究中,我们评估了骨髓中铁储存的等级,正如在全血细胞减少症患者的各种疾病中所看到的那样。材料和方法:对印度西部一家三级医疗中心140例全血细胞减少症患者骨髓抽吸液中铁的储存情况进行评估,采用Perls染色和Gales分级系统。结果:全血细胞减少患者中,铁储量低的占60.71%,正常的占30%,高铁储量的占9.29%。二形性贫血的铁储量在0-3级之间,其中72.4%的人铁储量低,24.6%的人铁储量正常,2.8%的人铁储量高。巨幼细胞性贫血表现为铁储存等级在0-4级之间,缺铁性贫血表现为铁储存降低,并伴有多发性骨髓瘤、急性淋巴细胞白血病和再生障碍性贫血。结论:Gale分级法对骨髓吸液中铁含量分级方便、结果导向,可为临床医生制定相应的治疗方案提供参考。
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引用次数: 0
Assessment of anxiety and behavior changes on digital education in undergraduate dental students during COVID-19 pandemic 新冠肺炎大流行期间牙科本科学生数字化教育焦虑与行为变化评估
IF 0.3 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-05-01 DOI: 10.4103/jss.jss_16_22
Shaila V Kothiwale, Vishakha Padhye
Context: Due to the COVID-19 pandemic, to avoid community spread of the disease, various academic institutions were closed to prevent infecting the students. Hence their relocation from the institution resulted in online academic learning. Reports indicated that the students undergoing online academic learning experienced distress in the form of anxiety, anger and insomnia. Aims: The aim of this study was to assess the changes in mental attitude, behavioral pattern, and anxiety level along with the impact of online education on academics so as to receive suggestions regarding digital education from undergraduate dental students. Settings and Design: An observational, cross-sectional study was conducted formulating online semi-structured, open-ended questionnaires, to obtain inputs regarding digital education using Google Forms and the snowball sampling method. Subjects and Methods: The data collection was initiated on August 6 at 4 PM IST and closed on August 13, 2020, at 4 PM IST. We received the response from 488 students from five dental institutions of Karnataka, Maharashtra, and Andhra Pradesh. Statistical analysis was performed using Microsoft Excel for obtaining an overall percentage of mental attitude, anxiety, behavior changes, and academics. IBM SPSS Statistics 20 software was used to evaluate correlation among all parameters with the analysis of variance test. Results: A statistically significant association was seen between digital education with anxiety (P = 0.015), behavior changes (P = 0.000), and academics (P = 0.000). Students contributed positive inputs to enhance the learning outcome in academics on the digital platform. Conclusions: Online academic sessions have eased the learning process to a certain extent, but this mode of education needs more refinement in the form of clinical demonstration videos, sharing of study material, well-planned and spaced definite timetable, and postsession evaluation. These suggestions were put forth by the students as feedback to make the experience entirely stress-free and aid their learning process.
背景:由于新冠肺炎大流行,为了避免疾病在社区传播,关闭了各种学术机构以防止感染学生。因此,他们从该机构的搬迁导致了在线学术学习。报告显示,接受在线学术学习的学生经历了焦虑、愤怒和失眠的痛苦。目的:本研究旨在评估在线教育对学术的影响,以及心理态度、行为模式和焦虑水平的变化,以获得牙科本科生对数字教育的建议。设置和设计:进行了一项观察性、横断面研究,制定了在线半结构化、开放式问卷,以使用谷歌表格和滚雪球抽样方法获得有关数字教育的投入。受试者和方法:数据收集于美国东部时间8月6日下午4点开始,于2020年8月13日美国东部时间下午4点结束。我们收到了来自卡纳塔克邦、马哈拉施特拉邦和安得拉邦五所牙科机构的488名学生的回复。使用Microsoft Excel进行统计分析,以获得心理态度、焦虑、行为变化和学业的总体百分比。采用IBM SPSS Statistics 20软件进行方差分析,评价各参数之间的相关性。结果:数字教育与焦虑(P=0.015)、行为变化(P=0.000)和学术(P=0.000。结论:在线学术会议在一定程度上缓解了学习过程,但这种教育模式需要更多的改进,包括临床演示视频、学习材料共享、计划周密、间隔明确的时间表以及课后评估。这些建议是由学生提出的反馈,以使体验完全没有压力,并有助于他们的学习过程。
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引用次数: 0
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