A. Kudachi, A. Hogade, S. Koppad, R. Mudhol, S. Javali
Objective: Preventive/regular health checkups have gained prominence over the past decade due to lifestyle-associated risks. The association of physical health checkups and mental health with “well-being,” remains unclear. Most of the time less attention is given to psychological health and its importance in physical health and disease. Patients with chronic illness may encounter irreversible changes in health status and may lead to mortality. This is closely related to psychological distress and approximately 6%–34% of the patients with chronic illness developed depression. The objective of the present study is to find the correlation between the psychological well-being and chronic disease of people attending the executive health checkup. Materials and Methods: A cross-sectional study was conducted in tertiary care hospital at Belagavi. The study enrolled 768 individuals based on 52% prevalence of hypertension reporting for an executive health checkup and evaluated their demographic profile and adapted “The Scales of Psychological Well-Being” SPARQ tool of (18 items) questionnaire. Results: The mean age of the participants was 67.06 ± 32.94 years and a M: F ratio was 2:1. Multiple linear regression equation of psychological wellbeing of patients (Y) in terms of parameters of chronic diseases was found to be under psychological wellbeing (Y) =331.1862-0.1378 BMI-0.0368SBP-0.7161DBP-0.2030 FBS + 0.2727 PPBS-30.8144 HBA1C-0.0682 cholesterol. Conclusions: There is a significant and negative relationship between psychological well-being with parameters of chronic diseases.
{"title":"Correlation between psychological well-being of people with chronic diseases in executive health checkup","authors":"A. Kudachi, A. Hogade, S. Koppad, R. Mudhol, S. Javali","doi":"10.4103/jss.jss_124_22","DOIUrl":"https://doi.org/10.4103/jss.jss_124_22","url":null,"abstract":"Objective: Preventive/regular health checkups have gained prominence over the past decade due to lifestyle-associated risks. The association of physical health checkups and mental health with “well-being,” remains unclear. Most of the time less attention is given to psychological health and its importance in physical health and disease. Patients with chronic illness may encounter irreversible changes in health status and may lead to mortality. This is closely related to psychological distress and approximately 6%–34% of the patients with chronic illness developed depression. The objective of the present study is to find the correlation between the psychological well-being and chronic disease of people attending the executive health checkup. Materials and Methods: A cross-sectional study was conducted in tertiary care hospital at Belagavi. The study enrolled 768 individuals based on 52% prevalence of hypertension reporting for an executive health checkup and evaluated their demographic profile and adapted “The Scales of Psychological Well-Being” SPARQ tool of (18 items) questionnaire. Results: The mean age of the participants was 67.06 ± 32.94 years and a M: F ratio was 2:1. Multiple linear regression equation of psychological wellbeing of patients (Y) in terms of parameters of chronic diseases was found to be under psychological wellbeing (Y) =331.1862-0.1378 BMI-0.0368SBP-0.7161DBP-0.2030 FBS + 0.2727 PPBS-30.8144 HBA1C-0.0682 cholesterol. Conclusions: There is a significant and negative relationship between psychological well-being with parameters of chronic diseases.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49281431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Three-dose COVID-19 Vaccine for hemodialysis patient: Expected usefulness","authors":"B. Joob, V. Wiwanitkit","doi":"10.4103/jss.jss_161_21","DOIUrl":"https://doi.org/10.4103/jss.jss_161_21","url":null,"abstract":"","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41375850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pearl Konikkara, B. Sahoo, Debkumar Pal, M. Taywade
The major purpose of posting MBBS students in community medicine is to understand the ground realities of different existing problems leading to the disease. The students chalk out possible solutions using the available resources and transform the solution to an intervention explicitly designed for the family or individual. Family Health Advisory Services provides a platform to learn the above intent, make family visits in the community, reach a community diagnosis associated with various prevailing and contributing factors, and finally formulate a structured and specific elucidation to root out the disease or health condition. The village visit during the posting in the department of community medicine is crucial for making the preventive and promotive steps before the arrival of ill-health conditions. It also thrills the motive of different schemes and programs by state and central government in their approach and consequence if appropriately and adequately implemented in the anticipated circumstance and situation. The current article explores how a student utilizes community posting to go deep into a family's running and prevailing problems, identify the responsible and probable causes, and find a feasible and possible solution concerning the family's affordability, accessibility, and acceptability.
{"title":"Theory and practice of learning through the family adaptation and field visits in medical school: A reflective perspective","authors":"Pearl Konikkara, B. Sahoo, Debkumar Pal, M. Taywade","doi":"10.4103/jss.jss_198_22","DOIUrl":"https://doi.org/10.4103/jss.jss_198_22","url":null,"abstract":"The major purpose of posting MBBS students in community medicine is to understand the ground realities of different existing problems leading to the disease. The students chalk out possible solutions using the available resources and transform the solution to an intervention explicitly designed for the family or individual. Family Health Advisory Services provides a platform to learn the above intent, make family visits in the community, reach a community diagnosis associated with various prevailing and contributing factors, and finally formulate a structured and specific elucidation to root out the disease or health condition. The village visit during the posting in the department of community medicine is crucial for making the preventive and promotive steps before the arrival of ill-health conditions. It also thrills the motive of different schemes and programs by state and central government in their approach and consequence if appropriately and adequately implemented in the anticipated circumstance and situation. The current article explores how a student utilizes community posting to go deep into a family's running and prevailing problems, identify the responsible and probable causes, and find a feasible and possible solution concerning the family's affordability, accessibility, and acceptability.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46605633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The process of medical education delivery has evolved constantly considering the rapid progress in the field of medical sciences, and the varied roles expected of a health-care professional. The current review has been done to explore the role of virtual reality in medical education, and to identify the potential challenges and the suggestions that can aid in the successful introduction of the same in the undergraduate teaching period. An extensive search of all materials related to the topic was carried out in the PubMed search engine, and a total of 23 articles were selected based on their suitability with the current review objectives and analyzed. Keywords used in the search include virtual reality and medical education in the title alone only. Virtual reality is a kind of dynamic and adaptive learning and has been associated with multiple benefits that extend much beyond what is being offered by conventional teaching. Regardless of the multiple benefits, we must realize that it should be used to keep the intended learning outcomes in mind, so as to ensure that it can be integrated into the curriculum effectively. In conclusion, the tool of virtual reality has all the potential to transform medical education delivery in the coming days. Since virtual reality advocates principles of adult learning and gives them a platform to apply their knowledge to practice and subsequently improve on, it is quite necessary that all the medical colleges look to introduce the same within their setup and integrate it with conventional learning.
{"title":"Virtual reality in medical institutions: Innovative tool to strengthen the process of delivery of medical education","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/jss.jss_159_21","DOIUrl":"https://doi.org/10.4103/jss.jss_159_21","url":null,"abstract":"The process of medical education delivery has evolved constantly considering the rapid progress in the field of medical sciences, and the varied roles expected of a health-care professional. The current review has been done to explore the role of virtual reality in medical education, and to identify the potential challenges and the suggestions that can aid in the successful introduction of the same in the undergraduate teaching period. An extensive search of all materials related to the topic was carried out in the PubMed search engine, and a total of 23 articles were selected based on their suitability with the current review objectives and analyzed. Keywords used in the search include virtual reality and medical education in the title alone only. Virtual reality is a kind of dynamic and adaptive learning and has been associated with multiple benefits that extend much beyond what is being offered by conventional teaching. Regardless of the multiple benefits, we must realize that it should be used to keep the intended learning outcomes in mind, so as to ensure that it can be integrated into the curriculum effectively. In conclusion, the tool of virtual reality has all the potential to transform medical education delivery in the coming days. Since virtual reality advocates principles of adult learning and gives them a platform to apply their knowledge to practice and subsequently improve on, it is quite necessary that all the medical colleges look to introduce the same within their setup and integrate it with conventional learning.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42441131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patient-reported outcome measures (PROMs) are increasingly being used in the field of physiotherapy. In India, they are primarily used to determine clinical improvement in patients following intervention or for clinical audit purposes. However, clinical, academic, and research professionals' understanding of the construct, development, and psychometric validation of PROMs are uncertain, on the darker side, and unclear. As a result, this state could potentially lead to significant constraints in practice in terms of proper PROM selection, application, and administration. Furthermore, the lack of availability of PROMs in the patients' native language may necessitate a cross-cultural approach.
{"title":"The cross-cultural adaptation process of a patient-reported outcome measure","authors":"T. Alagappan","doi":"10.4103/jss.jss_136_21","DOIUrl":"https://doi.org/10.4103/jss.jss_136_21","url":null,"abstract":"Patient-reported outcome measures (PROMs) are increasingly being used in the field of physiotherapy. In India, they are primarily used to determine clinical improvement in patients following intervention or for clinical audit purposes. However, clinical, academic, and research professionals' understanding of the construct, development, and psychometric validation of PROMs are uncertain, on the darker side, and unclear. As a result, this state could potentially lead to significant constraints in practice in terms of proper PROM selection, application, and administration. Furthermore, the lack of availability of PROMs in the patients' native language may necessitate a cross-cultural approach.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45622387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Modern anesthesia practice utilizes preemptive analgesia for providing pain relief postoperatively using oral drugs such as pregabalin and gabapentin which are otherwise used for chronic pain management. We aimed to determine which among the two is more proficient. Materials and Methods: This randomized double-blinded control study was done among 72 subjects undergoing lower abdominal surgeries under the subarachnoid block and they were randomly divided into three groups: Group 1 received a single dose of tablet pregabalin 150 mg orally, Group 2 received tablet gabapentin 600 mg orally, and Group 3 received placebo drug orally (tablet B-complex) 2 h before subarachnoid block. Pain scores, time of 1st rescue analgesic, total number of rescue analgesics, sedation score, and occurrence of side effects were also noted for 24 h. The data were analyzed using SPSS 16 with Chi-square/Fisher's exact test or analysis of variance/Kruskal–Wallis test. A statistically significant difference was considered when P < 0.05. Results: Pain scores were lesser in Group 1 and 2 except at 2nd h. Total rescue analgesic time among maximum subjects in Group 1 was 4 h 30 min, in Group 2 was 3 h 30 min and 4 h, whereas in Group 3 was 3 h (P < 0.001). The total dose of analgesics in the first 24 h was 2 doses in Group 1, 2 doses in Group 2, and 3 doses in Group 3 (P < 0.001). Sedation score was more on Group 1 and 2 in comparison to Group 3 with no side effects in all groups. Conclusions: We conclude that pregabalin to be the effective preemptive drug because of its lesser pain intensity scores and good sedation property.
{"title":"A randomized trial comparing the efficacy of oral preemptive pregabalin and gabapentin for postoperative analgesia","authors":"T. Prasad, Pavithra Prabu, K. Priyadharsini","doi":"10.4103/jss.jss_182_22","DOIUrl":"https://doi.org/10.4103/jss.jss_182_22","url":null,"abstract":"Background: Modern anesthesia practice utilizes preemptive analgesia for providing pain relief postoperatively using oral drugs such as pregabalin and gabapentin which are otherwise used for chronic pain management. We aimed to determine which among the two is more proficient. Materials and Methods: This randomized double-blinded control study was done among 72 subjects undergoing lower abdominal surgeries under the subarachnoid block and they were randomly divided into three groups: Group 1 received a single dose of tablet pregabalin 150 mg orally, Group 2 received tablet gabapentin 600 mg orally, and Group 3 received placebo drug orally (tablet B-complex) 2 h before subarachnoid block. Pain scores, time of 1st rescue analgesic, total number of rescue analgesics, sedation score, and occurrence of side effects were also noted for 24 h. The data were analyzed using SPSS 16 with Chi-square/Fisher's exact test or analysis of variance/Kruskal–Wallis test. A statistically significant difference was considered when P < 0.05. Results: Pain scores were lesser in Group 1 and 2 except at 2nd h. Total rescue analgesic time among maximum subjects in Group 1 was 4 h 30 min, in Group 2 was 3 h 30 min and 4 h, whereas in Group 3 was 3 h (P < 0.001). The total dose of analgesics in the first 24 h was 2 doses in Group 1, 2 doses in Group 2, and 3 doses in Group 3 (P < 0.001). Sedation score was more on Group 1 and 2 in comparison to Group 3 with no side effects in all groups. Conclusions: We conclude that pregabalin to be the effective preemptive drug because of its lesser pain intensity scores and good sedation property.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42809504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Conservative treatment of the traumatized immature vital permanent teeth is considered critical step for rehabilitating with continued normal development of root and apex closure without adverse sequelae. Hence, the present article describes the case series of successfully and effectively managing the fractured vital immature permanent teeth (Ellis Class-II and Ellis Class-III dental trauma) in pediatric patients by employing three different conservative Vital Pulp Therapy (VPT) approaches using suitable sealing/pulp-capping agents to promote apexogenesis, followed by functional and esthetic restoration. In all the three presented cases, Apexogenesis was achieved without any unfavorable outcome like pulpal or periapical sequelae. Furthermore, the current dental literature relevant to VPT procedures for apexogenesis in young permanent teeth has been thoroughly described in this article.
{"title":"Successful rehabilitation of traumatized immature teeth by different vital pulp therapies in pediatric patients: A case series and literature review","authors":"Mohammad Khan","doi":"10.4103/jss.jss_138_22","DOIUrl":"https://doi.org/10.4103/jss.jss_138_22","url":null,"abstract":"Conservative treatment of the traumatized immature vital permanent teeth is considered critical step for rehabilitating with continued normal development of root and apex closure without adverse sequelae. Hence, the present article describes the case series of successfully and effectively managing the fractured vital immature permanent teeth (Ellis Class-II and Ellis Class-III dental trauma) in pediatric patients by employing three different conservative Vital Pulp Therapy (VPT) approaches using suitable sealing/pulp-capping agents to promote apexogenesis, followed by functional and esthetic restoration. In all the three presented cases, Apexogenesis was achieved without any unfavorable outcome like pulpal or periapical sequelae. Furthermore, the current dental literature relevant to VPT procedures for apexogenesis in young permanent teeth has been thoroughly described in this article.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44747256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yash Bafna, R. Mehta, S. Fernandes, Dharati S. Patel, H. Mistry, Kavya Shah
Aims: This questionnaire-based survey was designed to assess the acquaintance, apprehension, and perceptions of parents toward the COVID-19 pandemic and toward seeking dental care for their children in Visnagar, Gujarat, India. Settings and Design: This was a questionnaire-based cross-sectional study. Subjects and Methods: The online Google survey form included 6 units with 27 close-ended questions in twin languages (regional and English). Inquiries covered demographics, changes in daily acts, dietary traditions, and preparedness to seek child oral care during November 2020 to January 2021. Results: Out of 400 parents, 172 responded to the electronic survey form. Over half of the guardians affirmed that alveolar treatment could fan out COVID-19. Around 90% resorted to medication (self-medication – 39%, home remedies – 32.6%, and teledentistry – 17.4%) to evade personal dental visits for their children. Conclusions: The awareness about COVID-19 and precautions was significantly high. Though parents were unaware about safeguards practiced by dentists during Covid19. Measures were taken to correct misconceptions among parents about safe dental procedures.
{"title":"Attitude of parents toward child's dental health during the COVID-19 pandemic among the population of visnagar, Gujarat: A cross-sectional study","authors":"Yash Bafna, R. Mehta, S. Fernandes, Dharati S. Patel, H. Mistry, Kavya Shah","doi":"10.4103/jss.jss_157_22","DOIUrl":"https://doi.org/10.4103/jss.jss_157_22","url":null,"abstract":"Aims: This questionnaire-based survey was designed to assess the acquaintance, apprehension, and perceptions of parents toward the COVID-19 pandemic and toward seeking dental care for their children in Visnagar, Gujarat, India. Settings and Design: This was a questionnaire-based cross-sectional study. Subjects and Methods: The online Google survey form included 6 units with 27 close-ended questions in twin languages (regional and English). Inquiries covered demographics, changes in daily acts, dietary traditions, and preparedness to seek child oral care during November 2020 to January 2021. Results: Out of 400 parents, 172 responded to the electronic survey form. Over half of the guardians affirmed that alveolar treatment could fan out COVID-19. Around 90% resorted to medication (self-medication – 39%, home remedies – 32.6%, and teledentistry – 17.4%) to evade personal dental visits for their children. Conclusions: The awareness about COVID-19 and precautions was significantly high. Though parents were unaware about safeguards practiced by dentists during Covid19. Measures were taken to correct misconceptions among parents about safe dental procedures.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49644770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Human immunodeficiency virus (HIV) and tuberculosis (TB) have a synergistic effect. Suppression of the immune system by HIV increases the risk for TB infection in people living with HIV (PLHIV). It is known for many years that isoniazid 300 mg for a period of 6 months is given for the prevention of TB. Aim: The present study is a prospective study to assess adverse drug reaction (ADR) and patient adherence to isoniazid in HIV patients on antiretroviral therapy (ART). Subjects and Methods: A prospective observational study was carried out for a period of 2 months, i.e., January 2021 and February 2021, in the department of ART at a tertiary care teaching hospital, Kakinada. This study was approved by the institutional ethics committee. The adherence to Isoniazid Preventive Therapy (IPT) was assessed using Morisky Medication Adherence Scale, and all the ADRs reported were assessed for clinical pattern, causality, severity, and preventability. Results: Out of 122 reports, a total of 37 reactions occurred in 24 people. Rash and itching are the majorly reported ADRs, followed by headache and giddiness. According to the WHO causality assessment scale, 21 (87.5%) of the reported cases were probable and 3 (12.5%) were possibly related to suspected medication. Major ADRs were mild (91.6%) according to the severity assessment done by Modified Hartwig and Siegel Scale. Conclusions: Medication adherence is good (61.4%) in the majority of the population (PLHIV), in spite of mild ADRs. The majority of ADRs are mild in nature and the necessity for dechallenge did not arise. Most of the ADRs come under probable, and the majority of them are preventable by proper periodic assessment.
人类免疫缺陷病毒(HIV)和结核病(TB)具有协同效应。艾滋病毒对免疫系统的抑制增加了艾滋病毒感染者感染结核病的风险。多年来，人们都知道异烟肼300毫克，为期6个月用于预防结核病。目的:本研究是一项前瞻性研究，评估HIV患者抗逆转录病毒治疗(ART)的药物不良反应(ADR)和患者对异烟肼的依从性。研究对象和方法:于2021年1月和2021年2月在Kakinada一家三级护理教学医院ART科室开展了为期2个月的前瞻性观察性研究。本研究已获机构伦理委员会批准。使用Morisky药物依从性量表评估异烟肼预防治疗(IPT)的依从性，并评估所有报告的不良反应的临床模式、因果关系、严重程度和可预防性。结果:122例报告中，24例患者共发生37例反应。皮疹和瘙痒是主要报告的不良反应，其次是头痛和头晕。根据WHO因果评定量表，报告病例中可能病例21例(87.5%)，疑似用药病例3例(12.5%)。根据修正Hartwig and Siegel量表的严重程度评估，严重不良反应为轻度(91.6%)。结论:尽管有轻微的不良反应，但大多数人群(PLHIV)的药物依从性良好(61.4%)。大多数不良反应是轻微的，没有必要进行挑战。大多数不良反应是可能发生的，其中大多数是可以通过适当的定期评估来预防的。
{"title":"Medication adherence and adverse drug reactions of isoniazid preventive therapy for tuberculosis in people living with HIV (PLHIV) in a tertiary care teaching hospital, Kakinada","authors":"M. Kruthika, K. Devi, K. Prasad, Pilla Devi","doi":"10.4103/jss.jss_195_22","DOIUrl":"https://doi.org/10.4103/jss.jss_195_22","url":null,"abstract":"Introduction: Human immunodeficiency virus (HIV) and tuberculosis (TB) have a synergistic effect. Suppression of the immune system by HIV increases the risk for TB infection in people living with HIV (PLHIV). It is known for many years that isoniazid 300 mg for a period of 6 months is given for the prevention of TB. Aim: The present study is a prospective study to assess adverse drug reaction (ADR) and patient adherence to isoniazid in HIV patients on antiretroviral therapy (ART). Subjects and Methods: A prospective observational study was carried out for a period of 2 months, i.e., January 2021 and February 2021, in the department of ART at a tertiary care teaching hospital, Kakinada. This study was approved by the institutional ethics committee. The adherence to Isoniazid Preventive Therapy (IPT) was assessed using Morisky Medication Adherence Scale, and all the ADRs reported were assessed for clinical pattern, causality, severity, and preventability. Results: Out of 122 reports, a total of 37 reactions occurred in 24 people. Rash and itching are the majorly reported ADRs, followed by headache and giddiness. According to the WHO causality assessment scale, 21 (87.5%) of the reported cases were probable and 3 (12.5%) were possibly related to suspected medication. Major ADRs were mild (91.6%) according to the severity assessment done by Modified Hartwig and Siegel Scale. Conclusions: Medication adherence is good (61.4%) in the majority of the population (PLHIV), in spite of mild ADRs. The majority of ADRs are mild in nature and the necessity for dechallenge did not arise. Most of the ADRs come under probable, and the majority of them are preventable by proper periodic assessment.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45502007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Joshi, Niraj S. Gokhale, S. Hugar, Sanjana P. Soneta, Chandrashekhar M. Badakar, N. Saxena
Background: Restoration of caries having multisurface involvement in primary teeth is a challenge to dentists. The success of the restoration often depends on its longevity. Hence, it is important to systematically review the longevity of stainless steel crowns (SSCs) on primary molars. Objectives: To determine the longevity of SSC and to determine the reasons of failure for the same. Data Sources: A systematic search was conducted in three databases: PubMed, Embase, and Google Scholar for the studies published from January 1, 2009 to September 25, 2019. Cross references of the selected articles were also searched and hand searching was done for the studies whose full texts were not available through the electronic search. Gray literature was also searched for the studies according to the relevance of this review. Study Eligibility: Studies were included if they were published between January 1, 2009 and September 25, 2019, which included comparative assessment of SSCs and other multisurface restorations in primary teeth. The study setting should be clinical based. The study designs included in the review were prospective, retrospective, and randomized control clinical trials. Studies written in the English language and studies written in any other language but are possible to get translated into English were included. Reviews, letters to the editor, and short communications were not included in the review. Studies conducted in permanent dentition were not included. For meta-analysis, randomized control trials and retrospective studies were included. Results: 1398 records were identified through data search using search strategy in PubMed, Google Scholar, and through Gray literature. After further exclusion, the total number of articles came out to be 41. Finally, six articles were included in the systematic review. These articles were also subjected to meta-analysis. The pooled success rate for SSC over 12 months was shown to be 96.096%. This was seen to be significantly higher. Conclusion: SSCs showed good longevity than the other restorative materials on primary molars.
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