Conservative treatment of the traumatized immature vital permanent teeth is considered critical step for rehabilitating with continued normal development of root and apex closure without adverse sequelae. Hence, the present article describes the case series of successfully and effectively managing the fractured vital immature permanent teeth (Ellis Class-II and Ellis Class-III dental trauma) in pediatric patients by employing three different conservative Vital Pulp Therapy (VPT) approaches using suitable sealing/pulp-capping agents to promote apexogenesis, followed by functional and esthetic restoration. In all the three presented cases, Apexogenesis was achieved without any unfavorable outcome like pulpal or periapical sequelae. Furthermore, the current dental literature relevant to VPT procedures for apexogenesis in young permanent teeth has been thoroughly described in this article.
{"title":"Successful rehabilitation of traumatized immature teeth by different vital pulp therapies in pediatric patients: A case series and literature review","authors":"Mohammad Khan","doi":"10.4103/jss.jss_138_22","DOIUrl":"https://doi.org/10.4103/jss.jss_138_22","url":null,"abstract":"Conservative treatment of the traumatized immature vital permanent teeth is considered critical step for rehabilitating with continued normal development of root and apex closure without adverse sequelae. Hence, the present article describes the case series of successfully and effectively managing the fractured vital immature permanent teeth (Ellis Class-II and Ellis Class-III dental trauma) in pediatric patients by employing three different conservative Vital Pulp Therapy (VPT) approaches using suitable sealing/pulp-capping agents to promote apexogenesis, followed by functional and esthetic restoration. In all the three presented cases, Apexogenesis was achieved without any unfavorable outcome like pulpal or periapical sequelae. Furthermore, the current dental literature relevant to VPT procedures for apexogenesis in young permanent teeth has been thoroughly described in this article.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"111 - 117"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44747256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yash Bafna, R. Mehta, S. Fernandes, Dharati S. Patel, H. Mistry, Kavya Shah
Aims: This questionnaire-based survey was designed to assess the acquaintance, apprehension, and perceptions of parents toward the COVID-19 pandemic and toward seeking dental care for their children in Visnagar, Gujarat, India. Settings and Design: This was a questionnaire-based cross-sectional study. Subjects and Methods: The online Google survey form included 6 units with 27 close-ended questions in twin languages (regional and English). Inquiries covered demographics, changes in daily acts, dietary traditions, and preparedness to seek child oral care during November 2020 to January 2021. Results: Out of 400 parents, 172 responded to the electronic survey form. Over half of the guardians affirmed that alveolar treatment could fan out COVID-19. Around 90% resorted to medication (self-medication – 39%, home remedies – 32.6%, and teledentistry – 17.4%) to evade personal dental visits for their children. Conclusions: The awareness about COVID-19 and precautions was significantly high. Though parents were unaware about safeguards practiced by dentists during Covid19. Measures were taken to correct misconceptions among parents about safe dental procedures.
{"title":"Attitude of parents toward child's dental health during the COVID-19 pandemic among the population of visnagar, Gujarat: A cross-sectional study","authors":"Yash Bafna, R. Mehta, S. Fernandes, Dharati S. Patel, H. Mistry, Kavya Shah","doi":"10.4103/jss.jss_157_22","DOIUrl":"https://doi.org/10.4103/jss.jss_157_22","url":null,"abstract":"Aims: This questionnaire-based survey was designed to assess the acquaintance, apprehension, and perceptions of parents toward the COVID-19 pandemic and toward seeking dental care for their children in Visnagar, Gujarat, India. Settings and Design: This was a questionnaire-based cross-sectional study. Subjects and Methods: The online Google survey form included 6 units with 27 close-ended questions in twin languages (regional and English). Inquiries covered demographics, changes in daily acts, dietary traditions, and preparedness to seek child oral care during November 2020 to January 2021. Results: Out of 400 parents, 172 responded to the electronic survey form. Over half of the guardians affirmed that alveolar treatment could fan out COVID-19. Around 90% resorted to medication (self-medication – 39%, home remedies – 32.6%, and teledentistry – 17.4%) to evade personal dental visits for their children. Conclusions: The awareness about COVID-19 and precautions was significantly high. Though parents were unaware about safeguards practiced by dentists during Covid19. Measures were taken to correct misconceptions among parents about safe dental procedures.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"66 - 70"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49644770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandhya Tamgadge, A. Tamgadge, Bhagyashree Agre, Gayatri Pendse, Amisha Nayak
Teeth are considered to be the prime organs for mastication, speech, and esthetics. The basic structure of tooth involves enamel, dentin, and pulp. Each of these is formed by specialized structures during the various phases of tooth development. One of such specialized structures forming dentin of the tooth are odontoblasts. Being present at the periphery of the pulp chamber, they are in close contact with dentin through cytoplasmic extensions which travel into the entire length of dentin through dentinal tubules. In addition to dentin formation, they play a vital role in performing the various functions of the tooth including nerve sensation. They are functionally active throughout the life span of a healthy tooth and are subjective to numerous injuries causing various oral lesions. This review aims to collect the information with an additional note on the role of odontoblasts and their characteristics in a healthy and diseased tooth structure, their significance in endodontics and three-dimensional (3D) histological means.
{"title":"Odontoblasts in health and disease with an additional note on its three-Dimensional histological perspective","authors":"Sandhya Tamgadge, A. Tamgadge, Bhagyashree Agre, Gayatri Pendse, Amisha Nayak","doi":"10.4103/jss.jss_101_22","DOIUrl":"https://doi.org/10.4103/jss.jss_101_22","url":null,"abstract":"Teeth are considered to be the prime organs for mastication, speech, and esthetics. The basic structure of tooth involves enamel, dentin, and pulp. Each of these is formed by specialized structures during the various phases of tooth development. One of such specialized structures forming dentin of the tooth are odontoblasts. Being present at the periphery of the pulp chamber, they are in close contact with dentin through cytoplasmic extensions which travel into the entire length of dentin through dentinal tubules. In addition to dentin formation, they play a vital role in performing the various functions of the tooth including nerve sensation. They are functionally active throughout the life span of a healthy tooth and are subjective to numerous injuries causing various oral lesions. This review aims to collect the information with an additional note on the role of odontoblasts and their characteristics in a healthy and diseased tooth structure, their significance in endodontics and three-dimensional (3D) histological means.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"4 - 9"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41815190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Thalamus is an oval mass of gray matter between the third ventricle and the internal capsule. The medial, spinal, and trigeminal lemnisci are the great ascending sensory projections from the periphery. The lateral and medial geniculate bodies transmit the visual and auditory information to the cortex. The thalamus also contains motor projections from the basal ganglia, on their way to the motor cortex and supplementary motor area. Materials and Methods: Over 2-year period from November 2015 onward, 83 patients with magnetic resonance imaging confirmed nontraumatic thalamic lesions were identified, and followed up. The patient population consisted of adults above 18 years of age. They were investigated as to the cause of the lesion and treated. Results: There were 58 male patients, 25 female patients. Stroke was the major cause while less common diseases causing thalamic lesions were demyelination, tumor, calcification, and gliosis. The lesions were more common on the left side. The extent of thalamic involvement was global (50.6%) most commonly. The next common was posteromedial affection (18.1%) and dorsal thalamus (14.5%). Corresponding motor weakness (57.8%) was the most common symptom, though other symptoms such as sensory loss (30.1%), ataxia (27.7%), memory loss (12%), and gaze paresis (30.1%) were also present. Headache (31.3%) and giddiness (24%) were less common than motor weakness. Speech disturbance was seen in 49.4% of patients. Discussion: Stroke is unilateral disease, while venous thrombosis, demyelination, tumor, metabolic diseases and infection can affect thalami bilaterally. While stroke can explain the sudden onset of sensory and motor disturbances, some features like cognitive dysfunction were difficult to explain. A transient disorientation to time can follow acute anterior thalamic lesions. Some patients had language disturbances suggesting that the language dominance can extend down up to thalamus. Chronic pain can also be due to a gliotic lesion in the thalamus. Upward gaze palsy seen in a third of our patients could be due to global thalamic or due to medial longitudinal fasciculus involvement. Two patients had visual hemineglect. Sleep disturbances could also be observed in thalamic disease. Asterixis and hemifacial spasm were not seen in our patients. Three patients with strokes had brachial onset seizures, and one patient had generalized seizures. Different types of gait disturbances were observed in thalamic disease including ataxia, astasia-abasia, and hemiparetic gait. Conclusion: The most common thalamic lesion was an ischemic stroke, followed by bleed. Global thalamic involvement was more common than other partial lesions, though posteromedial and dorsal lesions are also commonly seen. Sensorimotor dysfunction is the most common clinical presentation and less frequent presentations include aphasia, memory disturbances, behavioral, and cognitive dysfunction. Movement disorders, ataxic gait, sleep distu
{"title":"Thalamus - The gateway to cerebral cortex","authors":"Radhakrishna Hari, B. Padhy, Mitalee Kar","doi":"10.4103/jss.jss_142_21","DOIUrl":"https://doi.org/10.4103/jss.jss_142_21","url":null,"abstract":"Introduction: Thalamus is an oval mass of gray matter between the third ventricle and the internal capsule. The medial, spinal, and trigeminal lemnisci are the great ascending sensory projections from the periphery. The lateral and medial geniculate bodies transmit the visual and auditory information to the cortex. The thalamus also contains motor projections from the basal ganglia, on their way to the motor cortex and supplementary motor area. Materials and Methods: Over 2-year period from November 2015 onward, 83 patients with magnetic resonance imaging confirmed nontraumatic thalamic lesions were identified, and followed up. The patient population consisted of adults above 18 years of age. They were investigated as to the cause of the lesion and treated. Results: There were 58 male patients, 25 female patients. Stroke was the major cause while less common diseases causing thalamic lesions were demyelination, tumor, calcification, and gliosis. The lesions were more common on the left side. The extent of thalamic involvement was global (50.6%) most commonly. The next common was posteromedial affection (18.1%) and dorsal thalamus (14.5%). Corresponding motor weakness (57.8%) was the most common symptom, though other symptoms such as sensory loss (30.1%), ataxia (27.7%), memory loss (12%), and gaze paresis (30.1%) were also present. Headache (31.3%) and giddiness (24%) were less common than motor weakness. Speech disturbance was seen in 49.4% of patients. Discussion: Stroke is unilateral disease, while venous thrombosis, demyelination, tumor, metabolic diseases and infection can affect thalami bilaterally. While stroke can explain the sudden onset of sensory and motor disturbances, some features like cognitive dysfunction were difficult to explain. A transient disorientation to time can follow acute anterior thalamic lesions. Some patients had language disturbances suggesting that the language dominance can extend down up to thalamus. Chronic pain can also be due to a gliotic lesion in the thalamus. Upward gaze palsy seen in a third of our patients could be due to global thalamic or due to medial longitudinal fasciculus involvement. Two patients had visual hemineglect. Sleep disturbances could also be observed in thalamic disease. Asterixis and hemifacial spasm were not seen in our patients. Three patients with strokes had brachial onset seizures, and one patient had generalized seizures. Different types of gait disturbances were observed in thalamic disease including ataxia, astasia-abasia, and hemiparetic gait. Conclusion: The most common thalamic lesion was an ischemic stroke, followed by bleed. Global thalamic involvement was more common than other partial lesions, though posteromedial and dorsal lesions are also commonly seen. Sensorimotor dysfunction is the most common clinical presentation and less frequent presentations include aphasia, memory disturbances, behavioral, and cognitive dysfunction. Movement disorders, ataxic gait, sleep distu","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"88 - 96"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47534148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Archana, K. Benachinmardi, SuraAnjanappa Lakshminarayana, R. Prakash, S. Sangeetha
Background and Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019. Cycle threshold (Ct) value of real-time reverse transcription polymerase chain reaction (RT-PCR) assay inversely correlated with viral load and can provide an indirect method of quantifying the number of copies of viral RNA in the sample is not reported clinically. Hence, this study was undertaken to compare the Ct values of patients tested positive for SARS CoV-2 by RT-PCR with severity of illness, duration of hospital stay, and mortality. Materials and Methods: A retrospective study was conducted over a period of 6 months in a tertiary care hospital in Bangalore. All patients tested positive for SARS CoV-2 by RT-PCR and admitted in our hospital were included in the study. Details of the patients on the duration of hospital stay, age, presence of comorbidities, intubation, and mortality were collected. Results: The study comprised of 80 patients, 48 (60%) males and 32 (40%) females. The mean age of the study population was 38.38 years. Majority of patients 41.25% had Ct value between 25 and 30. Patients with lower Ct values were significant associated with increased duration of hospital stay and infected more than one person in family indicating higher probability of transmission of infection. Mortality showed significant association with patients of more than 60 years' age. Interpretation and Conclusions: The study shows possible association between Ct values of SARS-CoV-2 RT-PCR assay with the duration of hospitalization, infectivity, and mortality. Mention of Ct value along with the positive report could potentially be used to guide patient care management, infection control, and occupational health decisions.
{"title":"Importance of cycle threshold values in detection of severity and outcome in patients with severe acute respiratory syndrome coronavirus 2","authors":"B. Archana, K. Benachinmardi, SuraAnjanappa Lakshminarayana, R. Prakash, S. Sangeetha","doi":"10.4103/jss.jss_170_22","DOIUrl":"https://doi.org/10.4103/jss.jss_170_22","url":null,"abstract":"Background and Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019. Cycle threshold (Ct) value of real-time reverse transcription polymerase chain reaction (RT-PCR) assay inversely correlated with viral load and can provide an indirect method of quantifying the number of copies of viral RNA in the sample is not reported clinically. Hence, this study was undertaken to compare the Ct values of patients tested positive for SARS CoV-2 by RT-PCR with severity of illness, duration of hospital stay, and mortality. Materials and Methods: A retrospective study was conducted over a period of 6 months in a tertiary care hospital in Bangalore. All patients tested positive for SARS CoV-2 by RT-PCR and admitted in our hospital were included in the study. Details of the patients on the duration of hospital stay, age, presence of comorbidities, intubation, and mortality were collected. Results: The study comprised of 80 patients, 48 (60%) males and 32 (40%) females. The mean age of the study population was 38.38 years. Majority of patients 41.25% had Ct value between 25 and 30. Patients with lower Ct values were significant associated with increased duration of hospital stay and infected more than one person in family indicating higher probability of transmission of infection. Mortality showed significant association with patients of more than 60 years' age. Interpretation and Conclusions: The study shows possible association between Ct values of SARS-CoV-2 RT-PCR assay with the duration of hospitalization, infectivity, and mortality. Mention of Ct value along with the positive report could potentially be used to guide patient care management, infection control, and occupational health decisions.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"75 - 78"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44149948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Human immunodeficiency virus (HIV) and tuberculosis (TB) have a synergistic effect. Suppression of the immune system by HIV increases the risk for TB infection in people living with HIV (PLHIV). It is known for many years that isoniazid 300 mg for a period of 6 months is given for the prevention of TB. Aim: The present study is a prospective study to assess adverse drug reaction (ADR) and patient adherence to isoniazid in HIV patients on antiretroviral therapy (ART). Subjects and Methods: A prospective observational study was carried out for a period of 2 months, i.e., January 2021 and February 2021, in the department of ART at a tertiary care teaching hospital, Kakinada. This study was approved by the institutional ethics committee. The adherence to Isoniazid Preventive Therapy (IPT) was assessed using Morisky Medication Adherence Scale, and all the ADRs reported were assessed for clinical pattern, causality, severity, and preventability. Results: Out of 122 reports, a total of 37 reactions occurred in 24 people. Rash and itching are the majorly reported ADRs, followed by headache and giddiness. According to the WHO causality assessment scale, 21 (87.5%) of the reported cases were probable and 3 (12.5%) were possibly related to suspected medication. Major ADRs were mild (91.6%) according to the severity assessment done by Modified Hartwig and Siegel Scale. Conclusions: Medication adherence is good (61.4%) in the majority of the population (PLHIV), in spite of mild ADRs. The majority of ADRs are mild in nature and the necessity for dechallenge did not arise. Most of the ADRs come under probable, and the majority of them are preventable by proper periodic assessment.
人类免疫缺陷病毒(HIV)和结核病(TB)具有协同效应。艾滋病毒对免疫系统的抑制增加了艾滋病毒感染者感染结核病的风险。多年来，人们都知道异烟肼300毫克，为期6个月用于预防结核病。目的:本研究是一项前瞻性研究，评估HIV患者抗逆转录病毒治疗(ART)的药物不良反应(ADR)和患者对异烟肼的依从性。研究对象和方法:于2021年1月和2021年2月在Kakinada一家三级护理教学医院ART科室开展了为期2个月的前瞻性观察性研究。本研究已获机构伦理委员会批准。使用Morisky药物依从性量表评估异烟肼预防治疗(IPT)的依从性，并评估所有报告的不良反应的临床模式、因果关系、严重程度和可预防性。结果:122例报告中，24例患者共发生37例反应。皮疹和瘙痒是主要报告的不良反应，其次是头痛和头晕。根据WHO因果评定量表，报告病例中可能病例21例(87.5%)，疑似用药病例3例(12.5%)。根据修正Hartwig and Siegel量表的严重程度评估，严重不良反应为轻度(91.6%)。结论:尽管有轻微的不良反应，但大多数人群(PLHIV)的药物依从性良好(61.4%)。大多数不良反应是轻微的，没有必要进行挑战。大多数不良反应是可能发生的，其中大多数是可以通过适当的定期评估来预防的。
{"title":"Medication adherence and adverse drug reactions of isoniazid preventive therapy for tuberculosis in people living with HIV (PLHIV) in a tertiary care teaching hospital, Kakinada","authors":"M. Kruthika, K. Devi, K. Prasad, Pilla Devi","doi":"10.4103/jss.jss_195_22","DOIUrl":"https://doi.org/10.4103/jss.jss_195_22","url":null,"abstract":"Introduction: Human immunodeficiency virus (HIV) and tuberculosis (TB) have a synergistic effect. Suppression of the immune system by HIV increases the risk for TB infection in people living with HIV (PLHIV). It is known for many years that isoniazid 300 mg for a period of 6 months is given for the prevention of TB. Aim: The present study is a prospective study to assess adverse drug reaction (ADR) and patient adherence to isoniazid in HIV patients on antiretroviral therapy (ART). Subjects and Methods: A prospective observational study was carried out for a period of 2 months, i.e., January 2021 and February 2021, in the department of ART at a tertiary care teaching hospital, Kakinada. This study was approved by the institutional ethics committee. The adherence to Isoniazid Preventive Therapy (IPT) was assessed using Morisky Medication Adherence Scale, and all the ADRs reported were assessed for clinical pattern, causality, severity, and preventability. Results: Out of 122 reports, a total of 37 reactions occurred in 24 people. Rash and itching are the majorly reported ADRs, followed by headache and giddiness. According to the WHO causality assessment scale, 21 (87.5%) of the reported cases were probable and 3 (12.5%) were possibly related to suspected medication. Major ADRs were mild (91.6%) according to the severity assessment done by Modified Hartwig and Siegel Scale. Conclusions: Medication adherence is good (61.4%) in the majority of the population (PLHIV), in spite of mild ADRs. The majority of ADRs are mild in nature and the necessity for dechallenge did not arise. Most of the ADRs come under probable, and the majority of them are preventable by proper periodic assessment.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"79 - 82"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45502007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neha Phate, S. Acharya, S. Shukla, S. Sushanth Kumar, P. Banode
Takayasu's disease (TD) also known as pulseless disease is an arteriopathy characterized by vasculitis affecting the aorta and its branches. It is also known as aortic arch syndrome, nonspecific aorto-arteritis, and young female arteritis. Pulmonary artery involvement in Takayasu's arteritis is a rare phenomenon. Pulmonary artery vasculitis leads to pulmonary arterial hypertension and rarely manifests as pleural effusion. Patients with pulmonary arteritis and pleural effusion usually present as chest pain, cough, and dyspnea. Percentage of involvement of pulmonary artery in TD is variable. Pleural effusion occurs as sequelae of pulmonary artery involvement. We report the case of a 46-year-old female who presented to us with fever, weight loss, dyspnea, and chest pain. Clinical examination and investigations revealed Takayasu's arteritis and tubercular empyema. This case report is a rare presentation of Takayasu's arteritis with tubercular empyema without pulmonary arteritis.
{"title":"Takayasu's disease presenting with tubercular empyema: A rare presentation of a rare disease","authors":"Neha Phate, S. Acharya, S. Shukla, S. Sushanth Kumar, P. Banode","doi":"10.4103/jss.jss_126_22","DOIUrl":"https://doi.org/10.4103/jss.jss_126_22","url":null,"abstract":"Takayasu's disease (TD) also known as pulseless disease is an arteriopathy characterized by vasculitis affecting the aorta and its branches. It is also known as aortic arch syndrome, nonspecific aorto-arteritis, and young female arteritis. Pulmonary artery involvement in Takayasu's arteritis is a rare phenomenon. Pulmonary artery vasculitis leads to pulmonary arterial hypertension and rarely manifests as pleural effusion. Patients with pulmonary arteritis and pleural effusion usually present as chest pain, cough, and dyspnea. Percentage of involvement of pulmonary artery in TD is variable. Pleural effusion occurs as sequelae of pulmonary artery involvement. We report the case of a 46-year-old female who presented to us with fever, weight loss, dyspnea, and chest pain. Clinical examination and investigations revealed Takayasu's arteritis and tubercular empyema. This case report is a rare presentation of Takayasu's arteritis with tubercular empyema without pulmonary arteritis.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"118 - 120"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46548534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Joshi, Niraj S. Gokhale, S. Hugar, Sanjana P. Soneta, Chandrashekhar M. Badakar, N. Saxena
Background: Restoration of caries having multisurface involvement in primary teeth is a challenge to dentists. The success of the restoration often depends on its longevity. Hence, it is important to systematically review the longevity of stainless steel crowns (SSCs) on primary molars. Objectives: To determine the longevity of SSC and to determine the reasons of failure for the same. Data Sources: A systematic search was conducted in three databases: PubMed, Embase, and Google Scholar for the studies published from January 1, 2009 to September 25, 2019. Cross references of the selected articles were also searched and hand searching was done for the studies whose full texts were not available through the electronic search. Gray literature was also searched for the studies according to the relevance of this review. Study Eligibility: Studies were included if they were published between January 1, 2009 and September 25, 2019, which included comparative assessment of SSCs and other multisurface restorations in primary teeth. The study setting should be clinical based. The study designs included in the review were prospective, retrospective, and randomized control clinical trials. Studies written in the English language and studies written in any other language but are possible to get translated into English were included. Reviews, letters to the editor, and short communications were not included in the review. Studies conducted in permanent dentition were not included. For meta-analysis, randomized control trials and retrospective studies were included. Results: 1398 records were identified through data search using search strategy in PubMed, Google Scholar, and through Gray literature. After further exclusion, the total number of articles came out to be 41. Finally, six articles were included in the systematic review. These articles were also subjected to meta-analysis. The pooled success rate for SSC over 12 months was shown to be 96.096%. This was seen to be significantly higher. Conclusion: SSCs showed good longevity than the other restorative materials on primary molars.
{"title":"Longevity of stainless steel crowns on primary molars - A systematic review and meta-analysis","authors":"R. Joshi, Niraj S. Gokhale, S. Hugar, Sanjana P. Soneta, Chandrashekhar M. Badakar, N. Saxena","doi":"10.4103/jss.jss_164_22","DOIUrl":"https://doi.org/10.4103/jss.jss_164_22","url":null,"abstract":"Background: Restoration of caries having multisurface involvement in primary teeth is a challenge to dentists. The success of the restoration often depends on its longevity. Hence, it is important to systematically review the longevity of stainless steel crowns (SSCs) on primary molars. Objectives: To determine the longevity of SSC and to determine the reasons of failure for the same. Data Sources: A systematic search was conducted in three databases: PubMed, Embase, and Google Scholar for the studies published from January 1, 2009 to September 25, 2019. Cross references of the selected articles were also searched and hand searching was done for the studies whose full texts were not available through the electronic search. Gray literature was also searched for the studies according to the relevance of this review. Study Eligibility: Studies were included if they were published between January 1, 2009 and September 25, 2019, which included comparative assessment of SSCs and other multisurface restorations in primary teeth. The study setting should be clinical based. The study designs included in the review were prospective, retrospective, and randomized control clinical trials. Studies written in the English language and studies written in any other language but are possible to get translated into English were included. Reviews, letters to the editor, and short communications were not included in the review. Studies conducted in permanent dentition were not included. For meta-analysis, randomized control trials and retrospective studies were included. Results: 1398 records were identified through data search using search strategy in PubMed, Google Scholar, and through Gray literature. After further exclusion, the total number of articles came out to be 41. Finally, six articles were included in the systematic review. These articles were also subjected to meta-analysis. The pooled success rate for SSC over 12 months was shown to be 96.096%. This was seen to be significantly higher. Conclusion: SSCs showed good longevity than the other restorative materials on primary molars.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"28 - 38"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41938196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cerebellar liponeurocytoma is a rare clinicopathological entity, included in the 2000 World Health Organization (WHO) classification of tumors of the central nervous system in the category of glioneuronal tumors. These are WHO Grade II, slow-growing tumors in adults with known recurrences. To date, about 70 cases of liponeurocytomas have been reported. This tumor needs to be differentiated from oligodendroglioma as well as medulloblastoma which are more common and aggressive, requiring postoperative chemoradiation. A high index of suspicion is thus advocated for the diagnosis. We present one such case of this rare entity reported in our institute. A 42-year-old female presented with a 4-month history of headache, neck pain, reduced vision, and cerebellar signs. Imaging showed a midline lesion involving the cerebellar vermis and left lobe suggestive of anaplastic ependymoma/hemangioblastoma. The final diagnosis of cerebellar liponeurocytoma was rendered on routine histopathological examination supported by immunohistochemical analysis.
{"title":"Cerebellar Liponeurocytoma: Report of a Rare Entity","authors":"Kritika Singh, Ashvini Kolhe, Naina Goel","doi":"10.4103/jss.jss_130_22","DOIUrl":"https://doi.org/10.4103/jss.jss_130_22","url":null,"abstract":"Cerebellar liponeurocytoma is a rare clinicopathological entity, included in the 2000 World Health Organization (WHO) classification of tumors of the central nervous system in the category of glioneuronal tumors. These are WHO Grade II, slow-growing tumors in adults with known recurrences. To date, about 70 cases of liponeurocytomas have been reported. This tumor needs to be differentiated from oligodendroglioma as well as medulloblastoma which are more common and aggressive, requiring postoperative chemoradiation. A high index of suspicion is thus advocated for the diagnosis. We present one such case of this rare entity reported in our institute. A 42-year-old female presented with a 4-month history of headache, neck pain, reduced vision, and cerebellar signs. Imaging showed a midline lesion involving the cerebellar vermis and left lobe suggestive of anaplastic ependymoma/hemangioblastoma. The final diagnosis of cerebellar liponeurocytoma was rendered on routine histopathological examination supported by immunohistochemical analysis.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"108 - 110"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45532506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Insulin resistance (IR) is a defining feature of obesity, diabetes, and cardiovascular disease, and it contributes to many of the metabolic syndrome's abnormalities. Although our understanding of IR has vastly increased over time, several parts of its assessment continue to elude researchers and doctors. Although the quantitative assessment of insulin sensitivity is not regularly utilized in biochemical investigations for diagnostic purposes, the growing importance of IR has led to further research into its application. IR must be assessed in a number of clinical situations when insulin sensitivity is reduced. IR is being studied more and more in numerous disease states to help researchers better understand its pathophysiology, etiology, and implications. The gold standard approach for determining insulin sensitivity is the hyperinsulinemic euglycemic glucose clamp, although it is impractical due to its labor- and time-intensive nature. As a result, a variety of surrogate indices have been used to make determining IR easier and more accurate. The goal of this study is to highlight different elements and approaches for present and future insulin sensitivity/resistance measurements. Understanding and exploiting the condition will be aided by a thorough understanding of these signs.
{"title":"Insulin resistance and its detection tools: A narrative review","authors":"J. Mahajan, S. Acharya, S. Sushanth Kumar","doi":"10.4103/jss.jss_122_22","DOIUrl":"https://doi.org/10.4103/jss.jss_122_22","url":null,"abstract":"Insulin resistance (IR) is a defining feature of obesity, diabetes, and cardiovascular disease, and it contributes to many of the metabolic syndrome's abnormalities. Although our understanding of IR has vastly increased over time, several parts of its assessment continue to elude researchers and doctors. Although the quantitative assessment of insulin sensitivity is not regularly utilized in biochemical investigations for diagnostic purposes, the growing importance of IR has led to further research into its application. IR must be assessed in a number of clinical situations when insulin sensitivity is reduced. IR is being studied more and more in numerous disease states to help researchers better understand its pathophysiology, etiology, and implications. The gold standard approach for determining insulin sensitivity is the hyperinsulinemic euglycemic glucose clamp, although it is impractical due to its labor- and time-intensive nature. As a result, a variety of surrogate indices have been used to make determining IR easier and more accurate. The goal of this study is to highlight different elements and approaches for present and future insulin sensitivity/resistance measurements. Understanding and exploiting the condition will be aided by a thorough understanding of these signs.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":"50 1","pages":"19 - 22"},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44530622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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