Pub Date : 2025-10-16DOI: 10.1016/j.jormas.2025.102625
A. Khemis , R. Lan , F. Amatore , JM. Reimund , F. Campana , A. Falguière
Introduction
Persistent oral manifestations of Crohn's disease (CD), despite intestinal remission, remain a therapeutic challenge. This study aimed to describe two such cases and review available literature on management strategies.
Case reports
Despite infliximab and methotrexate, the first patient developed progressive oral lesions with only partial improvement under upadacitinib. The second achieved digestive remission under golimumab and successfully controlled oral lesions with intralesional corticosteroids.
Discussion
A literature review (Pubmed, ScienceDirect; up to January 2025) identified 17 articles involving 75 patients. Oral lesions appeared independently (54 %), concomitantly with digestive disease (20 %), or preceded it (26 %). Therapeutic responses were variable, with limited efficacy of anti-TNF antibodies, immunosuppressants, and corticosteroids. Anti-IL12/23 antibodies showed promising results in isolated cases, while data on anti-IL-23 antibodies and JAK inhibitors remain lacking.
Conclusion
Due to the absence of standardized therapeutic protocols, a personalized, multidisciplinary approach is essential. Further studies are needed to better define effective treatments.
{"title":"Refractory oral manifestations of Crohn's disease","authors":"A. Khemis , R. Lan , F. Amatore , JM. Reimund , F. Campana , A. Falguière","doi":"10.1016/j.jormas.2025.102625","DOIUrl":"10.1016/j.jormas.2025.102625","url":null,"abstract":"<div><h3>Introduction</h3><div>Persistent oral manifestations of Crohn's disease (CD), despite intestinal remission, remain a therapeutic challenge. This study aimed to describe two such cases and review available literature on management strategies.</div></div><div><h3>Case reports</h3><div>Despite infliximab and methotrexate, the first patient developed progressive oral lesions with only partial improvement under upadacitinib. The second achieved digestive remission under golimumab and successfully controlled oral lesions with intralesional corticosteroids.</div></div><div><h3>Discussion</h3><div>A literature review (Pubmed, ScienceDirect; up to January 2025) identified 17 articles involving 75 patients. Oral lesions appeared independently (54 %), concomitantly with digestive disease (20 %), or preceded it (26 %). Therapeutic responses were variable, with limited efficacy of anti-TNF antibodies, immunosuppressants, and corticosteroids. Anti-IL12/23 antibodies showed promising results in isolated cases, while data on anti-IL-23 antibodies and JAK inhibitors remain lacking.</div></div><div><h3>Conclusion</h3><div>Due to the absence of standardized therapeutic protocols, a personalized, multidisciplinary approach is essential. Further studies are needed to better define effective treatments.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 2","pages":"Article 102625"},"PeriodicalIF":2.0,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-16DOI: 10.1016/j.jormas.2025.102622
Ana Garcia-Martinez, Inmaculada Alguazas, Pia López-Jornet
Background
Burning Mouth Syndrome (BMS) is a chronic oral condition with complex management and variable treatment outcomes. Evaluating patient satisfaction can guide treatment choices and improve adherence.
Methods
This retrospective cross-sectional study included 151 patients diagnosed with BMS and treated at a university dental clinic. Clinical records were reviewed, and patient satisfaction was assessed using the Self-Assessment of Treatment Questionnaire (SAT-Q) and the Visual Analogue Scale (VAS). Five treatment types were analyzed: clonazepam, melatonin, α-lipoic acid, low-level laser therapy (LLLT), and phytotherapy.
Results
LLLT yielded the highest scores in symptom improvement (VAS = 4.21), perceived effectiveness (5.02), and overall satisfaction (SAT-Q = 73.91, p < 0.001). Clonazepam was associated with high adherence (93.8 %) but also a greater frequency of side effects (31.3 %). Side effects were not reported in the LLLT or α-lipoic acid groups. Univariate logistic regression showed that symptom relief (OR = 2.64, 95 % CI: 2.03–3.44), perceived effectiveness (OR = 2.07, 95 % CI: 1.71–2.50), and good adherence (OR = 3.81, 95 % CI: 1.95–7.42) were all significantly associated with higher treatment satisfaction (p < 0.001).
Conclusions
Patient satisfaction in BMS treatment is closely linked to clinical response, perceived effectiveness, and adherence. LLLT showed the most favorable profile in terms of both satisfaction and safety. These findings underscore the value of incorporating patient-reported outcomes in clinical decision-making for BMS management
{"title":"Patient satisfaction with treatments for burning mouth syndrome: A retrospective study using the self-assessment of treatment questionnaire and visual analogue scale","authors":"Ana Garcia-Martinez, Inmaculada Alguazas, Pia López-Jornet","doi":"10.1016/j.jormas.2025.102622","DOIUrl":"10.1016/j.jormas.2025.102622","url":null,"abstract":"<div><h3>Background</h3><div>Burning Mouth Syndrome (BMS) is a chronic oral condition with complex management and variable treatment outcomes. Evaluating patient satisfaction can guide treatment choices and improve adherence<em>.</em></div></div><div><h3>Methods</h3><div>This retrospective cross-sectional study included 151 patients diagnosed with BMS and treated at a university dental clinic. Clinical records were reviewed, and patient satisfaction was assessed using the Self-Assessment of Treatment Questionnaire (SAT-Q) and the Visual Analogue Scale (VAS). Five treatment types were analyzed: clonazepam, melatonin, α-lipoic acid, low-level laser therapy (LLLT), and phytotherapy.</div></div><div><h3>Results</h3><div>LLLT yielded the highest scores in symptom improvement (VAS = 4.21), perceived effectiveness (5.02), and overall satisfaction (SAT-Q = 73.91, p < 0.001). Clonazepam was associated with high adherence (93.8 %) but also a greater frequency of side effects (31.3 %). Side effects were not reported in the LLLT or α-lipoic acid groups. Univariate logistic regression showed that symptom relief (OR = 2.64, 95 % CI: 2.03–3.44), perceived effectiveness (OR = 2.07, 95 % CI: 1.71–2.50), and good adherence (OR = 3.81, 95 % CI: 1.95–7.42) were all significantly associated with higher treatment satisfaction (p < 0.001).</div></div><div><h3>Conclusions</h3><div>Patient satisfaction in BMS treatment is closely linked to clinical response, perceived effectiveness, and adherence. LLLT showed the most favorable profile in terms of both satisfaction and safety. These findings underscore the value of incorporating patient-reported outcomes in clinical decision-making for BMS management</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 1","pages":"Article 102622"},"PeriodicalIF":2.0,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nonsyndromic cleft lip and/or palate (NSCL/P) is a common congenital craniofacial anomaly with multifactorial etiology. Several genome-wide association studies (GWAS) have implicated polymorphisms in ABCA4 gene in correlation to NSCL/P. We conducted a trio-based SNP analysis to evaluate the role of rs560426 and rs4147811 in NSCL/P pathogenesis in an Indian population.
Methods
Blood samples were collected from 82 trios (father, mother, child), where child is affected by NSCL/P. Genomic DNA was extracted and genotyped for rs560426 and rs4147811 (ABCA4) using PCR Assay. Genotypic distributions were assessed, and transmission disequilibrium test (TDT) was performed on informative trios.
Results
For rs4147811, all individuals across trios were homozygous for the CC genotype, indicating monomorphism in this cohort. For rs560426, 77 trios showed CC genotype while 5 exhibited CG; no GG homozygotes were observed. TDT analysis on heterozygous parents (n=5) revealed borderline transmission bias of the G allele to affected offspring (p<0.05).
Conclusion
In this cohort, rs4147811 showed no polymorphism, and rs560426 exhibited variation. These findings suggest that these SNPs may play a role in NSCL/P in this regional population. Larger studies or broader genome-wide approaches may be required to identify relevant genetic risk factors.
{"title":"Association of ABCA4 gene polymorphisms with nonsyndromic cleft lip with or without cleft palate in a case-parent trio study","authors":"Mohammad Ashraf Ansari , K.Vinod Kumar , Bishnu Prasad Parida , Anjali Chauhan , Gopeshwar Narayan , Subodh Kumar Singh","doi":"10.1016/j.jormas.2025.102626","DOIUrl":"10.1016/j.jormas.2025.102626","url":null,"abstract":"<div><h3>Background</h3><div>Nonsyndromic cleft lip and/or palate (NSCL/P) is a common congenital craniofacial anomaly with multifactorial etiology. Several genome-wide association studies (GWAS) have implicated polymorphisms in ABCA4 gene in correlation to NSCL/P. We conducted a trio-based SNP analysis to evaluate the role of rs560426 and rs4147811 in NSCL/P pathogenesis in an Indian population.</div></div><div><h3>Methods</h3><div>Blood samples were collected from 82 trios (father, mother, child), where child is affected by NSCL/P. Genomic DNA was extracted and genotyped for rs560426 and rs4147811 (ABCA4) using PCR Assay. Genotypic distributions were assessed, and transmission disequilibrium test (TDT) was performed on informative trios.</div></div><div><h3>Results</h3><div>For rs4147811, all individuals across trios were homozygous for the CC genotype, indicating monomorphism in this cohort. For rs560426, 77 trios showed CC genotype while 5 exhibited CG; no GG homozygotes were observed. TDT analysis on heterozygous parents (n=5) revealed borderline transmission bias of the G allele to affected offspring (<em>p</em><0.05).</div></div><div><h3>Conclusion</h3><div>In this cohort, rs4147811 showed no polymorphism, and rs560426 exhibited variation. These findings suggest that these SNPs may play a role in NSCL/P in this regional population. Larger studies or broader genome-wide approaches may be required to identify relevant genetic risk factors.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 1","pages":"Article 102626"},"PeriodicalIF":2.0,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-10DOI: 10.1016/j.jormas.2025.102607
Federica Sobrero , Fabio Roccia , Gian Battista Bottini , Maximilian Goetzinger , Euan Rae , Sean Laverick , Carlo Strada , Guglielmo Ramieri , Constantinus Politis , Kathia Dubron , Anamaria Sivrić , Mario Kordić , Sajjad Abdur Rahman , Tabishur Rahman , Valfrido Antonio Pereira-Filho , Luis Fernando de Oliveira Gorla , Timothy Aladelusi , Karpal Singh Sohal , Marko Lazíc , Vitomir S. Konstantinovic , Anže Birk
OBJECTIVE(S)
Paediatric frontal fractures are uncommon injuries that may lead to significant complications. This study aimed to analyse patterns, surgical management, and outcomes of paediatric frontal sinus fractures in 14 maxillofacial centers worldwide.
METHODS
This multicentric retrospective study included patients ≤ 16 years of age operated for frontal fractures from January 2011 and December 2022. Collected data included: age, sex, cause of injury, site and type of fracture, surgical approach, nasofrontal outflow tract (NFOT) involvement, treatment, and outcome. Patients were divided based on the absence (group A) or presence (group B) of frontal sinus pneumatisation. Minimum follow-up was 6 months.
RESULTS
Thirty-two patients (mean age, 11.5 years) were included. Road traffic accidents were the main cause of injury (50%). In group A, 5/6 patients underwent open reduction and internal fixation (ORIF). In group B, 15 patients reported an isolated anterior table fracture, fixated with ORIF in 88% of cases. Nine patients reported combined anterior + posterior table fractures, 67% managed with anterior table fixation and cranialisation. One patient had an isolated posterior table fracture and underwent cranialisation. NFOT involvement was statistically associated with combined fractures (67%) (p=0.028) and managed with obliteration in 8/9 cases. Residual contour deformities of the frontal convexity were the most frequent complication (19%).
CONCLUSION
The surgical management varied by fracture site and sinus pneumatisation. Clinical outcomes were generally favourable, with residual contour deformities being the most common complications. Centers showed consistent approaches, but further multicenter studies are needed to establish definitive treatment strategies.
{"title":"Surgical management of paediatric frontal fractures with and without sinus pneumatisation: a multicentre study","authors":"Federica Sobrero , Fabio Roccia , Gian Battista Bottini , Maximilian Goetzinger , Euan Rae , Sean Laverick , Carlo Strada , Guglielmo Ramieri , Constantinus Politis , Kathia Dubron , Anamaria Sivrić , Mario Kordić , Sajjad Abdur Rahman , Tabishur Rahman , Valfrido Antonio Pereira-Filho , Luis Fernando de Oliveira Gorla , Timothy Aladelusi , Karpal Singh Sohal , Marko Lazíc , Vitomir S. Konstantinovic , Anže Birk","doi":"10.1016/j.jormas.2025.102607","DOIUrl":"10.1016/j.jormas.2025.102607","url":null,"abstract":"<div><h3>OBJECTIVE(S)</h3><div>Paediatric frontal fractures are uncommon injuries that may lead to significant complications. This study aimed to analyse patterns, surgical management, and outcomes of paediatric frontal sinus fractures in 14 maxillofacial centers worldwide.</div></div><div><h3>METHODS</h3><div>This multicentric retrospective study included patients ≤ 16 years of age operated for frontal fractures from January 2011 and December 2022. Collected data included: age, sex, cause of injury, site and type of fracture, surgical approach, nasofrontal outflow tract (NFOT) involvement, treatment, and outcome. Patients were divided based on the absence (group A) or presence (group B) of frontal sinus pneumatisation. Minimum follow-up was 6 months.</div></div><div><h3>RESULTS</h3><div>Thirty-two patients (mean age, 11.5 years) were included. Road traffic accidents were the main cause of injury (50%). In group A, 5/6 patients underwent open reduction and internal fixation (ORIF). In group B, 15 patients reported an isolated anterior table fracture, fixated with ORIF in 88% of cases. Nine patients reported combined anterior + posterior table fractures, 67% managed with anterior table fixation and cranialisation. One patient had an isolated posterior table fracture and underwent cranialisation. NFOT involvement was statistically associated with combined fractures (67%) (p=0.028) and managed with obliteration in 8/9 cases. Residual contour deformities of the frontal convexity were the most frequent complication (19%).</div></div><div><h3>CONCLUSION</h3><div>The surgical management varied by fracture site and sinus pneumatisation. Clinical outcomes were generally favourable, with residual contour deformities being the most common complications. Centers showed consistent approaches, but further multicenter studies are needed to establish definitive treatment strategies.</div></div><div><h3>Level of evidence</h3><div>3</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 2","pages":"Article 102607"},"PeriodicalIF":2.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral bone regeneration and associated complications: A systematic review and meta-analysis","authors":"Zoé Gaudimier , Samy Tawfik , Charles Kerouanton , Claudine Wulfman , Yohann Flottes","doi":"10.1016/j.jormas.2025.102606","DOIUrl":"10.1016/j.jormas.2025.102606","url":null,"abstract":"","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 2","pages":"Article 102606"},"PeriodicalIF":2.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-09DOI: 10.1016/j.jormas.2025.102603
Sameena Sandhu , Adib Al-Haj Husain , Victor Mergen , Tristan T. Demmert , Hatem Alkadhi , Thomas Flohr , Egon Burian , Bernd Stadlinger , Peter Kessler , Harald Essig , Maximilian Eberhard Hermann Wagner
Introduction
This ex vivo study aimed to compare photon-counting detector computed tomography (PCD-CT) and cone-beam computed tomography (CBCT) at matched standard- and low-dose radiation levels for evaluating perioperative imaging parameters relevant to mandibular fracture stabilization with osteosynthesis plates.
Material and Methods
Thirty-three osteosynthesis fixations were performed on six porcine mandibles with simulated fractures in the angle, body, and parasymphysis regions. Three types of plate systems (titanium microplates, titanium reconstruction plates, and bioresorbable copolymers) were used, each with varying plate thicknesses. Three blinded observers independently evaluated overall image quality, artifact severity, fracture line visibility, and visualization of peri‑osteosynthesis structures using 5-point visual analog scales. Descriptive statistics and inter-reader agreement (Krippendorff’s alpha) were calculated.
Results
PCD-CT consistently demonstrated superior overall image quality, reduced artifact severity, and better visualization of fracture lines and peri‑osteosynthetic structures compared to CBCT, particularly using low-dose settings. Bioresorbable plates caused no artifacts in either modality. Inter-observer agreement was good to excellent across all parameters (Krippendorff’s α = 0.72–1.0).
Conclusion
PCD-CT outperformed CBCT in visualizing mandibular fracture stabilization with various osteosynthesis materials, particularly under low-dose conditions, demonstrating high reliability among observers. These findings indicate that PCD-CT may offer diagnostic advantages in the perioperative setting; however, further clinical studies are needed to confirm its role in imaging oral and maxillofacial trauma.
{"title":"Comparative evaluation of photon-counting detector CT and cone-beam CT in the assessment of simulated mandibular trauma","authors":"Sameena Sandhu , Adib Al-Haj Husain , Victor Mergen , Tristan T. Demmert , Hatem Alkadhi , Thomas Flohr , Egon Burian , Bernd Stadlinger , Peter Kessler , Harald Essig , Maximilian Eberhard Hermann Wagner","doi":"10.1016/j.jormas.2025.102603","DOIUrl":"10.1016/j.jormas.2025.102603","url":null,"abstract":"<div><h3>Introduction</h3><div>This <em>ex vivo</em> study aimed to compare photon-counting detector computed tomography (PCD-CT) and cone-beam computed tomography (CBCT) at matched standard- and low-dose radiation levels for evaluating perioperative imaging parameters relevant to mandibular fracture stabilization with osteosynthesis plates.</div></div><div><h3>Material and Methods</h3><div>Thirty-three osteosynthesis fixations were performed on six porcine mandibles with simulated fractures in the angle, body, and parasymphysis regions. Three types of plate systems (titanium microplates, titanium reconstruction plates, and bioresorbable copolymers) were used, each with varying plate thicknesses. Three blinded observers independently evaluated overall image quality, artifact severity, fracture line visibility, and visualization of peri‑osteosynthesis structures using 5-point visual analog scales. Descriptive statistics and inter-reader agreement (Krippendorff’s alpha) were calculated.</div></div><div><h3>Results</h3><div>PCD-CT consistently demonstrated superior overall image quality, reduced artifact severity, and better visualization of fracture lines and peri‑osteosynthetic structures compared to CBCT, particularly using low-dose settings. Bioresorbable plates caused no artifacts in either modality. Inter-observer agreement was good to excellent across all parameters (Krippendorff’s α = 0.72–1.0).</div></div><div><h3>Conclusion</h3><div>PCD-CT outperformed CBCT in visualizing mandibular fracture stabilization with various osteosynthesis materials, particularly under low-dose conditions, demonstrating high reliability among observers. These findings indicate that PCD-CT may offer diagnostic advantages in the perioperative setting; however, further clinical studies are needed to confirm its role in imaging oral and maxillofacial trauma.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 2","pages":"Article 102603"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145259990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We report a case of soft tissue sarcoma (STS) arising in the temporomandibular joint (TMJ), a rare site associated with considerable functional and aesthetic challenges when resection is required. A 33-year-old female with neurofibromatosis type 1 presented with progressive swelling in the right TMJ. Imaging revealed an enlarging, irregular region. Histopathological findings were suggestive of a high-grade STS, but definitive subclassification was not possible. The patient declined surgery due to potential facial nerve injury and cosmetic concerns. As an alternative, a combination of carbon ion radiotherapy and AI chemotherapy (ifosfamide and doxorubicin) was administered. At 5 years and 7 months post-treatment, the patient remains recurrence-free with preserved function and appearance. This case highlights the therapeutic potential of multidisciplinary, non-surgical strategies for head and neck STS when histologic ambiguity exists and radical surgery poses significant risk.
{"title":"Carbon ion radiotherapy and AI chemotherapy for soft tissue sarcoma of the temporomandibular joint: A case report of 5-year disease-free survival without wide resection","authors":"Masahito Hara , Kentaro Nomura , Misa Sumi , Naoki Katase , Kei-ichiro Miura , Tomohiro Yamada","doi":"10.1016/j.jormas.2025.102616","DOIUrl":"10.1016/j.jormas.2025.102616","url":null,"abstract":"<div><div>We report a case of soft tissue sarcoma (STS) arising in the temporomandibular joint (TMJ), a rare site associated with considerable functional and aesthetic challenges when resection is required. A 33-year-old female with neurofibromatosis type 1 presented with progressive swelling in the right TMJ. Imaging revealed an enlarging, irregular region. Histopathological findings were suggestive of a high-grade STS, but definitive subclassification was not possible. The patient declined surgery due to potential facial nerve injury and cosmetic concerns. As an alternative, a combination of carbon ion radiotherapy and AI chemotherapy (ifosfamide and doxorubicin) was administered. At 5 years and 7 months post-treatment, the patient remains recurrence-free with preserved function and appearance. This case highlights the therapeutic potential of multidisciplinary, non-surgical strategies for head and neck STS when histologic ambiguity exists and radical surgery poses significant risk.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 2","pages":"Article 102616"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-09DOI: 10.1016/j.jormas.2025.102614
Sigifredo López-Ochoa , Luis Vicente González , Juan Pablo López
Background
Arthroscopic discopexy is a minimally invasive procedure for treating internal derangement of the temporomandibular joint (TMJ). However, a long learning curve limits its widespread adoption, as it is a technique that requires high skill, specialized instruments, and a high cost, as well as difficult access.
Objective
This study aims to propose a design for a new instrument, fabricate it, and evaluate a set of low-cost 3D-printed instruments to facilitate arthroscopic TMJ discopexy.
Methods
The instruments were designed using computer-aided design (CAD) software and fabricated with Kirschner nail, orthodontic pliers, and methacrylate via 3D printing. Also, a short case series is mentioned as a proof of concept.
Results and conclusions
The 3D-printed instruments were successfully used to perform the discopexy procedure in ten cases, demonstrating comparable performance to conventional instruments at a fraction of the cost without any complications related to instruments or surgical technique.
{"title":"In-house handcrafted 3D tools for arthroscopic discopexy of the temporomandibular joint. A technical note","authors":"Sigifredo López-Ochoa , Luis Vicente González , Juan Pablo López","doi":"10.1016/j.jormas.2025.102614","DOIUrl":"10.1016/j.jormas.2025.102614","url":null,"abstract":"<div><h3>Background</h3><div>Arthroscopic discopexy is a minimally invasive procedure for treating internal derangement of the temporomandibular joint (TMJ). However, a long learning curve limits its widespread adoption, as it is a technique that requires high skill, specialized instruments, and a high cost, as well as difficult access.</div></div><div><h3>Objective</h3><div>This study aims to propose a design for a new instrument, fabricate it, and evaluate a set of low-cost 3D-printed instruments to facilitate arthroscopic TMJ discopexy.</div></div><div><h3>Methods</h3><div>The instruments were designed using computer-aided design (CAD) software and fabricated with Kirschner nail, orthodontic pliers, and methacrylate via 3D printing. Also, a short case series is mentioned as a proof of concept.</div></div><div><h3>Results and conclusions</h3><div>The 3D-printed instruments were successfully used to perform the discopexy procedure in ten cases, demonstrating comparable performance to conventional instruments at a fraction of the cost without any complications related to instruments or surgical technique.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 1","pages":"Article 102614"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-09DOI: 10.1016/j.jormas.2025.102611
Shucong Yao , Li Tian, Leitao Zhang
Objective
Thyroglossal duct cysts (TDC) are the most common tumors occurring in the midline and anterior neck regions and may affect swallowing function, infection, and even malignant transformation. The incidence of malignant transformation in thyroglossal duct cysts is very low, at approximately 1 %. Thyroglossal duct cysts extending into or occupying the pre-epiglottic space are extremely rare.
Case series presentation
A 37-year-old male developed papillary thyroid carcinoma originating from thyroglossal duct cysts that occupied the pre-epiglottic space. The tumor was successfully resected using a modified Sistrunk procedure. The relevant literature was reviewed.
Conclusion
Malignant transformation of thyroglossal duct cysts may occur at any site. Malignancy can be suggested by preoperative ultrasound and imaging examinations, thereby necessitating clinical vigilance.
{"title":"Malignant transformation of a thyroglossal duct cyst located in the preepiglottic space: A case report and literature review","authors":"Shucong Yao , Li Tian, Leitao Zhang","doi":"10.1016/j.jormas.2025.102611","DOIUrl":"10.1016/j.jormas.2025.102611","url":null,"abstract":"<div><h3>Objective</h3><div>Thyroglossal duct cysts (TDC) are the most common tumors occurring in the midline and anterior neck regions and may affect swallowing function, infection, and even malignant transformation. The incidence of malignant transformation in thyroglossal duct cysts is very low, at approximately 1 %. Thyroglossal duct cysts extending into or occupying the pre-epiglottic space are extremely rare.</div></div><div><h3>Case series presentation</h3><div>A 37-year-old male developed papillary thyroid carcinoma originating from thyroglossal duct cysts that occupied the pre-epiglottic space. The tumor was successfully resected using a modified Sistrunk procedure. The relevant literature was reviewed.</div></div><div><h3>Conclusion</h3><div>Malignant transformation of thyroglossal duct cysts may occur at any site. Malignancy can be suggested by preoperative ultrasound and imaging examinations, thereby necessitating clinical vigilance.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 2","pages":"Article 102611"},"PeriodicalIF":2.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To evaluate the risk factors for postoperative nausea and vomiting (PONV) in patients undergoing orthognathic surgery, with particular emphasis on elucidating the potential relationship between PONV and the depth and duration of intraoperative hypotension (IOH).
Material and methods
We conducted a retrospective cohort study of patients who underwent orthognathic surgery between November 2022 and August 2024. Mean arterial pressure (MAP) was extracted from electronic medical records. Methods to evaluate IOH: 1. total area under curve (AUC); 2. time-weighted average (TWA) MAP; 3. cumulative time below absolute threshold values; 4. cumulative time in the lowest MAP categories. MAP thresholds were defined by absolute limits (≤ 65, ≤ 60, ≤ 55 mmHg).
Results
Of the 287 patients enrolled, five patients were excluded. At all absolute thresholds, patients experiencing PONV demonstrated significantly greater AUC and TWA than non-PONV patients (p < 0.05). Furthermore, at ≤ 60 and ≤ 55 mmHg threshold, PONV patients also exhibited significantly longer cumulative time of hypotensive (p < 0.05). When MAP is in 50–60 mmHg range for > 10 min (OR: 6.00, 95 % CI: 1.02–35.37), and when MAP is in ≤ 55 mmHg range for ≥ 5 min (OR: 0.42, 95 % CI: 0.20–0.90), were significantly associated with PONV (p < 0.05).
Conclusion
IOH may represent an additional important risk factor for PONV in patients undergoing orthognathic surgery, especially when MAP is in 50–60 mmHg range for > 10 min, or ≤ 55 mmHg range for ≥ 5 min.
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