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A three-dimensional comparison of the upper airway between patients with non-syndromic cleft lip and palate and skeletal class I individuals 非综合征型唇腭裂患者与骨骼I类个体上气道三维比较。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-27 DOI: 10.1016/j.jormas.2025.102668
Jiali Shi , Ruofan Jin , Nan Zhang , Fei Liu , Jinwei Qin , Wei Hou , Weina Zhou

Introduction

To compare the upper airway dimensions between patients with non-syndromic cleft lip and palate (NSCLP) and skeletal class I control group using three-dimensional imaging.

Methods

Using a retrospective cohort study, the investigators enrolled a sample of patients from the Orthodontic Department of the Affiliated Stomatological Hospital of Nanjing Medical University during 2014 and 2018. The primary predictor variable was dentofacial skeleton (NSCLP vs. skeletal class I). The main outcome was three-dimensional upper airway morphology, which included volume, minimum cross-sectional area, height, and symmetry. Appropriate statistics were computed using P < 0.05 as statistical significance.

Results

The study included 51 NSCLP patients and 53 class I controls, with comparable age and gender distribution. Three-dimensional analysis revealed significant morphological differences: compared to the class I group, NSCLP patients exhibited a larger nasopharyngeal volume (p < 0.01) and a larger minimum cross-sectional area in the nasopharynx (p < 0.05) and palatopharynx (p < 0.01), but a reduced height of the upper airway (p < 0.05) and palatopharyngeal airway (p < 0.01). Furthermore, in unilateral NSCLP patients, the transverse diameters of the nasopharynx and palatopharynx were significantly smaller on the affected side compared to the normal side (p < 0.05). While bilateral NSCLP and class I groups demonstrated symmetry at the nasopharyngeal and palatopharyngeal levels, both exhibited significant asymmetry at the glossopharyngeal segment (p < 0.05).

Conclusion

Our findings conclusively define the specific three-dimensional differences in the NSCLP upper airway, which include an enlarged yet foreshortened nasopharynx and consistent lateral asymmetries. These structural nuances must be considered in the interdisciplinary management of cleft lip and palate to optimize functional and structural results.
前言:应用三维成像技术比较非综合征性唇腭裂(NSCLP)患者与骨骼I类对照组的上气道尺寸。方法:采用回顾性队列研究方法,选取2014 - 2018年南京医科大学附属口腔医院正畸科住院患者为研究对象。主要预测变量是牙面骨骼(NSCLP vs骨骼I级)。主要结果是三维上气道形态,包括体积、最小横截面积、高度和对称性。以P < 0.05为差异有统计学意义。结果:该研究纳入51例NSCLP患者和53例I级对照,年龄和性别分布相似。三维分析显示了显著的形态学差异:与I级组相比,NSCLP患者表现出更大的鼻咽容积(p)结论:我们的研究结果明确定义了NSCLP上气道的特定三维差异,包括鼻咽扩大但缩短,以及一致的侧方不对称。这些结构上的细微差别必须在唇腭裂的跨学科管理中加以考虑,以优化功能和结构结果。
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引用次数: 0
A scoping review of modifications of the transconjunctival approach for maxillofacial fracture management and proposal of evidence-based algorithm for incision selection 颌面部骨折经结膜入路改良及切口选择循证算法的综述。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-26 DOI: 10.1016/j.jormas.2025.102670
Amanjot Kaur , Aparna Ganesan , Karthik Sennimalai , Kamalpreet Kaur

Background

The transconjunctival (TC) approach is widely utilized for orbital fracture repair due to its superior cosmetic outcomes compared to cutaneous incisions. However, concerns about limited surgical exposure, prolonged operative times, and lower eyelid complications have prompted several modifications of this technique.

Purpose

This scoping review aimed to systematically map and analyze the various modifications of the transconjunctival (TC) approach used for orbital and adjacent midface (infraorbital rim and zygomaticomaxillary complex) fracture repair, focusing on technical descriptions, clinical outcomes, and complications.

Study Selection

A systematic search of electronic databases was performed following PRISMA-ScR guidelines to identify studies reporting modifications of the TC approach. Inclusion criteria encompassed clinical studies, retrospective analyses, and case reports or series that described surgical techniques and reported outcomes. Studies describing TC approach modifications for orbital, infraorbital rim, or zygomatic fractures were included. Studies without specific details on modifications or outcomes were excluded. Of the initially identified articles, 22 studies met the inclusion criteria after independent screening by two reviewers.

Results

Twenty-two studies describing TC approach modifications were included, describing eight major categories of TC modifications. Reported variations included lateral paracanthal extensions, sutureless TC incisions, cutaneous Y-modifications, extended TC approaches, stair-step incisions, modified lateral canthotomy and aesthetic variations, lateral skin extensions and canthal-sparing techniques. These techniques were designed to improve surgical access and minimise complications such as ectropion, entropion, and scleral show. Some modifications prioritized enhanced exposure, while others focused on reducing morbidity and optimizing aesthetic results. Due to the heterogeneity of study designs and outcome measures, quantitative synthesis was not performed.

Conclusions and Relevance

The TC approach continues to evolve through multiple technical refinements that balance exposure and aesthetics. Awareness of these variants enables surgeons to individualise incision choices based on fracture patterns and risk profiles. The current evidence is largely descriptive and lacks standardised outcome measures, which limits direct comparisons. Prospective, well-designed studies are needed to establish the optimal modification for specific clinical contexts.
背景:经结膜(TC)入路因其优于皮肤切口的美观效果而被广泛应用于眶底骨折修复。然而,考虑到手术暴露有限、手术时间延长和下眼睑并发症,已经对这种技术进行了一些修改。目的:本综述旨在系统地绘制和分析用于眼眶和邻近中脸(眶下缘和颧腋复合体)骨折修复的经结膜(TC)入路的各种修改,重点关注技术描述、临床结果和并发症。研究选择:根据PRISMA-ScR指南对电子数据库进行系统搜索,以确定报告TC方法修改的研究。纳入标准包括临床研究、回顾性分析和描述手术技术和报告结果的病例系列。描述TC入路改良治疗眼眶、眶下缘或颧骨骨折的研究也包括在内。没有修改或结果的具体细节的研究被排除在外。在最初确定的文章中,经过两位评论者的独立筛选,有19篇研究符合纳入标准。结果:共纳入22项描述TC入路修改的研究,描述了8大类TC修改。报道的变异包括外侧棘旁延伸、无缝合的TC切口、皮肤y形修饰、扩展TC入路、阶梯切口和保留椎管技术。这些技术旨在改善手术通路,减少并发症,如外翻、内翻和巩膜露出。一些修改优先增加曝光,而其他侧重于减少发病率和优化美学效果。由于研究设计和结果测量的异质性,没有进行定量综合。结论和相关性:TC方法通过多种技术改进不断发展,以平衡曝光和美学。对这些变异的认识使外科医生能够根据骨折类型和风险概况来个性化选择切口。目前的证据主要是描述性的,缺乏标准化的结果测量,这限制了直接比较。需要前瞻性的、设计良好的研究来确定特定临床情况下的最佳修饰。
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引用次数: 0
Enhancing AI-driven diagnostics for supernumerary teeth: data consistency and dataset balance 增强人工智能驱动的多余牙齿诊断:数据一致性和数据集平衡。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-26 DOI: 10.1016/j.jormas.2025.102671
Weihao Cheng , Hangyu Zhu
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引用次数: 0
Maxillary bone and dento-alveolar changes in cleft lip and palate patients: Total maxillary distraction osteogenesis versus anterior maxillary segmental distraction osteogenesis 唇腭裂患者上颌骨和牙槽骨的变化:上颌全牵张成骨vs上颌前段牵张成骨。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-24 DOI: 10.1016/j.jormas.2025.102663
Thinzar Zaw , Shaohua Song , Aung Phyo Thu , Hsu Yin Min , Minsi Li , Zhong Wu , Xuanping Huang
This study aimed to evaluate maxillary bone and dento-alveolar changes in cleft lip and palate patients after total maxillary distraction osteogenesis (TMDO) and anterior maxillary segmental distraction osteogenesis (AMSDO).
The retrospective study included 18 cleft lip and palate patients who underwent either with TMDO or AMSDO. CBCT scans of individuals were obtained and measured at predistraction (T1), post distraction (T2). Linear and angular measurements of maxillary bone and dento-alveolar bone were performed using three-dimensional reconstruction images. For intragroup comparisons, a paired t-test or Wilcoxon signed-rank test was used. For intergroup comparisons, an independent t-test or Mann-Whitney U test was used, with the Bonferroni correction applied.
In sagittal plane, sella-nasion-point A angles (SNA) and overjet increased significantly after distraction osteogenesis in both groups, but greater value was found in TMDO group. Palatal length (ANS-PNS) was significantly increased more in AMSDO group compared to TMDO group. In the vertical plane, Nasion-ptm-point A angles (N-ptm-A) and overbite increased significantly in TMDO, but not in AMSDO. In the axial plane, there was a greater increase of posterior arch width and a decrease in anterior arch width in AMSDO but difference was not statistically significant.
TMDO is optimal for comprehensive profile correction, while AMSDO is ideal for increasing arch length. The distractor's angulation directly controls the magnitude of arch lengthening and vertical elongation.
本研究旨在评估唇腭裂患者在上颌全牵张成骨(TMDO)和上颌前段牵张成骨(AMSDO)后上颌骨和牙槽骨的变化。回顾性研究包括18例唇腭裂患者,他们接受了TMDO或AMSDO。获得个体的CBCT扫描,并在分心前(T1)和分心后(T2)进行测量。使用三维重建图像对上颌骨和牙槽骨进行线性和角度测量。对于组内比较,使用配对t检验或Wilcoxon符号秩检验。对于组间比较,使用独立t检验或Mann-Whitney U检验,并应用Bonferroni校正。矢状面牵张成骨后,两组鞍鼻点A角(SNA)和overjet均显著升高,但TMDO组的数值更大。与TMDO组相比,AMSDO组腭长(ANS-PNS)明显增加。在垂直平面上,TMDO组的nsion -ptm-point A角(N-ptm-A)和复咬合明显增加,而AMSDO组则无明显变化。在轴向面,AMSDO患者后弓宽度增大较大,前弓宽度减小较大,但差异无统计学意义。TMDO是综合轮廓校正的最佳选择,而AMSDO是目标弓扩展的理想选择。牵引器的成角直接控制弓伸长和垂直伸长的大小。
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引用次数: 0
Retraction notice to “Diagnostic and prognostic value of indicators of markers of bone metabolism in type 2 diabetes mellitus patients with UV functionalised dental implants” [J Stomatol Oral Maxillofac Surg (2023) 101608] “UV功能牙种植体对2型糖尿病患者骨代谢指标的诊断和预后价值”的撤回通知[J]口腔颌面外科杂志(2023):101608]
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-23 DOI: 10.1016/j.jormas.2025.102618
Hakob Khachatryan , Gagik Hakobyan
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引用次数: 0
Biomechanical evaluation of fixation systems in different segmental Le Fort I osteotomies: Patient-specific implants versus miniplates 不同节段Le Fort I截骨术中固定系统的生物力学评价:患者特异性植入物与微型钢板。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-22 DOI: 10.1016/j.jormas.2025.102666
Barış Erkut Türk, Mehmet Barış Şimşek

Background

Patient-specific implants (PSIs) are increasingly used in orthognathic surgery; however, their biomechanical performance in multi-segment Le Fort I osteotomies has not been fully clarified.

Objective

To compare stress distribution and mechanical stability of PSIs and conventional miniplates in two- and three-piece segmental Le Fort I osteotomies using finite element analysis.

Materials and methods

Four three-dimensional maxillary models were constructed with 5 mm advancement and 5 mm expansion. Each model was fixed with either PSIs or miniplates. Oblique (30°) and vertical (125 N) forces were applied to the premolar–molar region. Maximum and minimum principal stresses in bone and von Mises stresses in fixation plates were analyzed.

Results

Three-piece osteotomies with miniplates exhibited the highest stress concentrations in both bone and plates. PSI fixation consistently reduced stress magnitudes and promoted more uniform load transfer under both oblique and vertical loading.

Significance

Compared with conventional miniplates, PSIs may provide enhanced biomechanical stability in segmental Le Fort I osteotomies; however, further clinical validation is required.
背景:患者特异性种植体(PSIs)越来越多地用于正颌手术;然而,它们在多节段Le Fort I截骨术中的生物力学性能尚未完全阐明。目的:应用有限元分析方法比较两、三节段Le Fort I截骨术中PSIs与常规微型钢板的应力分布及力学稳定性。材料与方法:制作4个上颌三维模型,模型前移5mm,扩张5mm。每个模型用psi或微型钢板固定。斜(30°)力和垂直(125 N)力分别作用于前磨牙-磨牙区。分析了骨内最大、最小主应力和固定板内von Mises应力。结果:微型钢板三片截骨术中骨和钢板的应力浓度最高。PSI固定在倾斜和垂直载荷下均能降低应力大小,促进更均匀的载荷传递。意义:与传统微型钢板相比,PSIs可在节段性Le Fort I型截骨术中提供更好的生物力学稳定性;然而,需要进一步的临床验证。
{"title":"Biomechanical evaluation of fixation systems in different segmental Le Fort I osteotomies: Patient-specific implants versus miniplates","authors":"Barış Erkut Türk,&nbsp;Mehmet Barış Şimşek","doi":"10.1016/j.jormas.2025.102666","DOIUrl":"10.1016/j.jormas.2025.102666","url":null,"abstract":"<div><h3>Background</h3><div>Patient-specific implants (PSIs) are increasingly used in orthognathic surgery; however, their biomechanical performance in multi-segment Le Fort I osteotomies has not been fully clarified.</div></div><div><h3>Objective</h3><div>To compare stress distribution and mechanical stability of PSIs and conventional miniplates in two- and three-piece segmental Le Fort I osteotomies using finite element analysis.</div></div><div><h3>Materials and methods</h3><div>Four three-dimensional maxillary models were constructed with 5 mm advancement and 5 mm expansion. Each model was fixed with either PSIs or miniplates. Oblique (30°) and vertical (125 N) forces were applied to the premolar–molar region. Maximum and minimum principal stresses in bone and von Mises stresses in fixation plates were analyzed.</div></div><div><h3>Results</h3><div>Three-piece osteotomies with miniplates exhibited the highest stress concentrations in both bone and plates. PSI fixation consistently reduced stress magnitudes and promoted more uniform load transfer under both oblique and vertical loading.</div></div><div><h3>Significance</h3><div>Compared with conventional miniplates, PSIs may provide enhanced biomechanical stability in segmental Le Fort I osteotomies; however, further clinical validation is required.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102666"},"PeriodicalIF":2.0,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145598439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on: “Refractory oral manifestations of Crohn's disease” 点评:“克罗恩病的难治性口腔表现”。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-22 DOI: 10.1016/j.jormas.2025.102664
Lucas Alves da Mota Santana , Carlos Eduardo Palanch Repeke , Rajiv Gandhi Gopalsamy , Juliana Batista Melo da Fonte , Lysandro Pinto Borges
{"title":"Comment on: “Refractory oral manifestations of Crohn's disease”","authors":"Lucas Alves da Mota Santana ,&nbsp;Carlos Eduardo Palanch Repeke ,&nbsp;Rajiv Gandhi Gopalsamy ,&nbsp;Juliana Batista Melo da Fonte ,&nbsp;Lysandro Pinto Borges","doi":"10.1016/j.jormas.2025.102664","DOIUrl":"10.1016/j.jormas.2025.102664","url":null,"abstract":"","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102664"},"PeriodicalIF":2.0,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145598455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Programmed death-ligand 1 (PDL-1) expression in the oral mucosa of smokeless tobacco users from a low and middle-income country 程序性死亡配体1 (PDL-1)在中低收入国家无烟烟草使用者口腔黏膜中的表达
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-22 DOI: 10.1016/j.jormas.2025.102665
Shella S , Najma Baseer , Muhammad Shahzad , Sana Safi

Background

Smokeless tobacco use is one of the most common causes of oral cancer globally. Naswar, a type of locally manufactured smokeless tobacco product in Pakistan is also associated with high risk of oral cancer but the underlying mechanism of carcinogenicity is not known. Programmed Death-Ligand 1 (PDL-1) is a crucial protein in immune response regulation, particularly in cancer, and its role in Naswar users' oral mucosa remains poorly understood.

Objective

To investigate PDL-1 expression in the oral mucosa of Naswar users, elucidating its potential implications for oral health and cancer development.

Methodology

This lab-based comparative observational study involves male Naswar users and non-users (n = 50 each group) from Peshawar, Pakistan. Following a written informed consent, data on demographics, Naswar usage and oral health and hygiene practices were collected using standardized questionnaires. Clinical examinations, cytological smears, and saliva samples were obtained for analysis. Immunohistochemistry techniques were employed to assess PDL-1 expression in oral mucosa cells, and for statistical analyses SPSS-v27 was used to analyze the association between the Naswar usage and PDL-1 expression profile.

Results

Naswar users exhibited lower adherence to oral hygiene practices compared to non-users. Immunohistochemical analysis revealed varying levels of PDL-1 expression among Naswar users, with 86 % showing no expression, 10 % demonstrating weak expression, and 4 % exhibiting moderate expression, with a significant difference of p = 0.023, in contrast to non-users. Additionally, no significant association was found between oral hygiene status and PDL-1 expression among naswar users.

Conclusion

Naswar users exhibited higher levels of PD-L1, potentially suggesting a heightened immunomodulatory response or adaptive mechanism the immune system employs to dampen immune responses and maintain tissue homeostasis in the face of chronic irritation and potential cellular damage caused by toxic Naswar constituents.
背景:无烟烟草使用是全球口腔癌最常见的原因之一。巴基斯坦当地生产的一种无烟烟草产品Naswar也与口腔癌的高风险有关,但其潜在的致癌性机制尚不清楚。程序性死亡配体1 (Programmed Death-Ligand 1, PDL-1)是免疫反应调控的关键蛋白,特别是在癌症中,其在Naswar使用者口腔黏膜中的作用尚不清楚。目的:研究Naswar使用者口腔黏膜中PDL-1的表达,阐明其对口腔健康和癌症发展的潜在影响。方法:这项基于实验室的比较观察研究涉及来自巴基斯坦白沙瓦的男性纳斯瓦尔用户和非用户(每组n =50)。在获得书面知情同意后,使用标准化问卷收集了有关人口统计、纳斯瓦尔使用情况以及口腔健康和卫生习惯的数据。临床检查,细胞学涂片和唾液样本进行分析。采用免疫组织化学技术评估口腔黏膜细胞中PDL-1的表达,统计学分析采用SPSS-v27分析Naswar的使用与PDL-1表达谱的关系。结果:与非使用者相比,纳斯瓦尔使用者对口腔卫生习惯的依从性较低。免疫组织化学分析显示,在Naswar使用者中,PDL-1表达水平不同,86%的人无表达,10%的人表达弱,4%的人表达中度,与非使用者相比,差异有统计学意义p=0.023。此外,口腔卫生状况与纳斯瓦尔使用者中PDL-1的表达之间没有显著的关联。结论:纳斯瓦尔使用者表现出更高水平的PD-L1,可能表明免疫系统在面对慢性刺激和有毒纳斯瓦尔成分引起的潜在细胞损伤时,免疫系统采用增强的免疫调节反应或适应性机制来抑制免疫反应并维持组织稳态。
{"title":"Programmed death-ligand 1 (PDL-1) expression in the oral mucosa of smokeless tobacco users from a low and middle-income country","authors":"Shella S ,&nbsp;Najma Baseer ,&nbsp;Muhammad Shahzad ,&nbsp;Sana Safi","doi":"10.1016/j.jormas.2025.102665","DOIUrl":"10.1016/j.jormas.2025.102665","url":null,"abstract":"<div><h3>Background</h3><div>Smokeless tobacco use is one of the most common causes of oral cancer globally. Naswar, a type of locally manufactured smokeless tobacco product in Pakistan is also associated with high risk of oral cancer but the underlying mechanism of carcinogenicity is not known. Programmed Death-Ligand 1 (PDL-1) is a crucial protein in immune response regulation, particularly in cancer, and its role in Naswar users' oral mucosa remains poorly understood.</div></div><div><h3>Objective</h3><div>To investigate PDL-1 expression in the oral mucosa of Naswar users, elucidating its potential implications for oral health and cancer development.</div></div><div><h3>Methodology</h3><div>This lab-based comparative observational study involves male Naswar users and non-users (<em>n</em> = 50 each group) from Peshawar, Pakistan. Following a written informed consent, data on demographics, Naswar usage and oral health and hygiene practices were collected using standardized questionnaires. Clinical examinations, cytological smears, and saliva samples were obtained for analysis. Immunohistochemistry techniques were employed to assess PDL-1 expression in oral mucosa cells, and for statistical analyses SPSS-v27 was used to analyze the association between the Naswar usage and PDL-1 expression profile.</div></div><div><h3>Results</h3><div>Naswar users exhibited lower adherence to oral hygiene practices compared to non-users. Immunohistochemical analysis revealed varying levels of PDL-1 expression among Naswar users, with 86 % showing no expression, 10 % demonstrating weak expression, and 4 % exhibiting moderate expression, with a significant difference of <em>p</em> = 0.023, in contrast to non-users. Additionally, no significant association was found between oral hygiene status and PDL-1 expression among naswar users.</div></div><div><h3>Conclusion</h3><div>Naswar users exhibited higher levels of PD-L1, potentially suggesting a heightened immunomodulatory response or adaptive mechanism the immune system employs to dampen immune responses and maintain tissue homeostasis in the face of chronic irritation and potential cellular damage caused by toxic Naswar constituents.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 3","pages":"Article 102665"},"PeriodicalIF":2.0,"publicationDate":"2025-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145598442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening tools and strategies for early detection of oral cancer and potentially malignant disorders in rural and low-resource populations: A systematic review 在农村和低资源人群中早期发现口腔癌和潜在恶性疾病的筛查工具和策略:一项系统综述。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-22 DOI: 10.1016/j.jormas.2025.102667
Amrinderbir Singh , Gabriela Beraldo Dalben , Nizar Adio , Matheus de Castro Costa , Marina Lara de Carli , Marcella Ogenchuk , Felipe Fornias Sperandio
Oral cancer and its precursor lesions, known as oral potentially malignant disorders (OPMDs), present significant public health challenges due to high morbidity and mortality rates. These issues are particularly pronounced in rural and remote populations, where access to specialized care and early diagnostic services is limited. Socioeconomic disparities, healthcare provider shortages, and geographic isolation contribute to delayed diagnoses and poorer outcomes in these settings. This systematic review evaluated 40 studies focused on early detection strategies for OPMDs and oral squamous cell carcinoma (OSCC) in underserved populations, particularly in rural and low-resource environments. Across 136,257 participants, the review identified diverse screening tools including oral visual examinations, toluidine blue staining, autofluorescence, chemiluminescence, mobile health (mHealth) applications, and artificial intelligence (AI)-based image analysis. The use of low-cost, portable, and technology-driven tools, especially those enabling remote diagnosis and task-sharing with frontline health workers, showed promise in increasing diagnostic accuracy and screening reach. However, variability in performance, training needs, and follow-up adherence remain key limitations. The review also highlighted widespread use of community-based strategies and the value of interdisciplinary collaboration, particularly where dental specialists are not readily available. Innovative, context-sensitive screening tools supported by interdisciplinary networks hold strong potential to enhance early detection of OPMDs and OSCC in rural and underserved communities. Mobile technologies and AI applications are emerging as practical adjuncts to traditional screening methods. To optimize impact, future efforts should prioritize validation of these tools against histopathological standards and the integration of trained non-specialist health workers in community-based screening programs.
口腔癌及其前体病变,被称为口腔潜在恶性疾病(OPMDs),由于其高发病率和死亡率,对公共卫生构成了重大挑战。这些问题在农村和偏远人口中尤为突出,在那里获得专门护理和早期诊断服务的机会有限。在这些情况下,社会经济差异、医疗保健提供者短缺和地理隔离导致诊断延迟和预后较差。本系统综述评估了40项研究,重点关注服务不足人群,特别是农村和低资源环境中opmd和口腔鳞状细胞癌(OSCC)的早期检测策略。在136,257名参与者中,该综述确定了各种筛查工具,包括口腔视觉检查、甲苯胺蓝染色、自身荧光、化学发光、移动健康(mHealth)应用程序和基于人工智能(AI)的图像分析。使用低成本、便携式和技术驱动的工具,特别是那些能够实现远程诊断和与一线卫生工作者分担任务的工具,有望提高诊断准确性和筛查范围。然而,表现的可变性、训练需求和后续依从性仍然是主要的限制。该审查还强调了广泛使用基于社区的策略和跨学科合作的价值,特别是在牙科专家不容易获得的地方。在跨学科网络的支持下,创新的、对环境敏感的筛查工具具有强大的潜力,可以在农村和服务不足的社区加强opmd和OSCC的早期检测。移动技术和人工智能应用正在成为传统筛查方法的实用辅助手段。为了优化影响,未来的努力应优先验证这些工具是否符合组织病理学标准,并将训练有素的非专业卫生工作者纳入社区筛查计划。
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引用次数: 0
Simplifying intermaxillary fixation in orthognathic surgery using customized surgical archwire with clear aligners: a technical note and exemplifying case 在正颌手术中使用带明确矫正器的定制手术弓丝简化上颌间固定:一个技术说明和范例案例。
IF 2 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-19 DOI: 10.1016/j.jormas.2025.102662
Solène Chanteux , Cyril Debortoli , Frédérique Bally-Genet , Barbara Lerhe , Charles Savoldelli

Background

Clear aligners are increasingly integrated into orthognathic surgery workflows. However, the lack of rigid intraoperative anchorage limits their use to mild or moderate cases, as aligners alone cannot ensure stable intermaxillary fixation.

Objective

To describe a simplified, reproducible, and cost-effective technique using a customized cobalt–chromium surgical archwire that enables stable intermaxillary fixation in patients treated with clear aligners.

Technical note

A 47-year-old woman with skeletal Class III malocclusion underwent bimaxillary orthognathic surgery under aligner treatment. A CAD-designed cobalt–chromium archwire with interdental posts was bonded using a conventional three-step adhesive protocol. The procedure required approximately 25 min and allowed precise intraoperative traction without detachment or deformation. The optional use of a silicone positioning key improved bonding accuracy and reproducibility.

Conclusion

This technique provides rigid and evenly distributed anchorage without removing aligner attachments or adding brackets or screws. By enabling stable intra- and postoperative fixation, it removes a key limitation of aligner-based surgical planning. This expands the applicability of clear aligners to more complex orthognathic cases, such as segmental osteotomies or asymmetrical corrections, and improves the integration of aligners into modern surgical workflows.
背景:清晰对准器越来越多地融入正颌手术工作流程。然而,术中缺乏刚性锚固限制了它们在轻度或中度病例中的应用,因为仅靠矫直器不能确保稳定的上颌间固定。目的:描述一种使用定制钴铬手术弓丝的简化、可重复性和成本效益的技术,使使用透明矫正器治疗的患者能够稳定地固定上颌间。技术说明:一位47岁的女性骨骼III类错颌在矫正器治疗下接受了双颌正颌手术。采用传统的三步粘接方法,将cad设计的钴铬弓丝与牙间桩进行粘接。手术大约需要25分钟,术中精确牵引,无脱离或变形。硅胶定位键的可选使用提高了粘合精度和再现性。结论:该技术提供了刚性和均匀分布的支抗,无需移除对准器附着物或添加支架或螺钉。通过实现稳定的内固定和术后固定,它消除了基于对准器的手术计划的一个关键限制。这扩大了清晰对准器在更复杂的正颌病例中的适用性,如节段性截骨或不对称矫正,并改善了对准器与现代外科工作流程的整合。
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引用次数: 0
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Journal of Stomatology Oral and Maxillofacial Surgery
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