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Is bony attachment necessary for dynamic reference frame in navigation-assisted minimally invasive lumbar spine fusion surgery? 在导航辅助微创腰椎融合手术中,骨附件是否需要作为动态参考系?
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2019-01-01 DOI: 10.1080/24699322.2018.1542028
Hsi-Hsien Lin, Yueh-Hsiu Lu, Po-Hsin Chou, Ming-Chau Chang, Shih-Tien Wang, Chien-Lin Liu
Abstract This study aimed to compare the accuracy of navigation-assisted percutaneous pedicle screw insertions between traditional posterior superior iliac spine (PSIS) fixed and cutaneously fixed dynamic reference frame (DRF) in minimally invasive surgery of transforaminal lumbar interbody fusion (MIS TLIF). This is a prospective randomized clinical study. Between May 2016 and Nov 2017, 100 patients who underwent MIS TLIF were randomly divided into bone fixed group (with PSIS fixed DRF) and skin fixed group (with cutaneously fixed DRF). The pedicel screws were inserted under navigational guidance using computed tomography (CT) data acquired intraoperatively with a Ziehm 3-dimensional fluoroscopy-based navigation system. Screw positions were immediately checked by a final intraoperative scan. The accuracy of screw placement was evaluated by a sophisticated computed tomography protocol. Both groups had similar patient demographics. Totally Five-hundred Twelve pedicle screws were placed in the lumbar spine. There were 2 moderate (2–4 mm) pedicle perforations in each group. The accuracy showed no significant difference between bone fixed and skin fixed DRF. There were no significant procedure-related complications. The skin fixed DRF provides similar accuracy in pedicle screw insertions with bone fixed DRF using intraoperative 3D image guided navigation in MIS TLIF. Skin fixed DRF not only serves as an alternative method but also saves a separate incision wound for bony attachment.
摘要本研究旨在比较传统髂后上棘(PSIS)固定和经皮固定动态参考系(DRF)在微创经椎间孔腰椎融合术(MIS TLIF)中导航辅助经皮椎弓根螺钉插入的准确性。这是一项前瞻性随机临床研究。在2016年5月至2017年11月期间,100名接受MIS TLIF的患者被随机分为骨固定组(采用PSIS固定DRF)和皮肤固定组(使用皮肤固定的DRF)。椎弓根螺钉在导航引导下插入,使用Ziehm三维荧光透视导航系统在手术中获得的计算机断层扫描(CT)数据。术中最后一次扫描立即检查螺钉位置。通过复杂的计算机断层扫描方案评估螺钉放置的准确性。两组患者的人口统计数据相似。共有512枚椎弓根螺钉植入腰椎。有2名中度(2-4 mm)椎弓根穿孔。骨固定DRF和皮肤固定DRF的准确性无显著差异。没有明显的手术相关并发症。皮肤固定DRF在MIS TLIF中使用术中3D图像引导导航,在椎弓根螺钉插入中提供与骨固定DRF相似的准确性。皮肤固定DRF不仅是一种替代方法,而且还省去了用于骨附着的单独切口伤口。
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引用次数: 5
Physiological interference reduction for near infrared spectroscopy brain activity measurement based on recursive least squares adaptive filtering and least squares support vector machines. 基于递推最小二乘自适应滤波和最小二乘支持向量机的近红外光谱脑活动测量生理干扰抑制。
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2019-01-01 DOI: 10.1080/24699322.2018.1560095
Xin Liu, Yan Zhang, Dan Liu, Qisong Wang, Ou Bai, Jinwei Sun, P. Rolfe
Near infrared spectroscopy is the promising and noninvasive technique that can be used to detect the brain functional activation by monitoring the concentration alternations in the haemodynamic concentration. The acquired NIRS signals are commonly contaminated by physiological interference caused by breathing and cardiac contraction. Though the adaptive filtering method with least mean squares algorithm or recursive least squares algorithm based on multidistance probe configuration could improve the quality of evoked brain activity response, both methods can only remove the physiological interference occurred in superficial layers of the head tissue. To overcome the shortcoming, we combined the recursive least squares adaptive filtering method with the least squares support vector machine to suppress physiological interference both in the superficial layers and deeper layers of the head tissue. The quantified results based on performance measures suggest that the estimation performances of the proposed method for the evoked haemodynamic changes are better than the traditional recursive least squares method.
近红外光谱技术是一种很有前途的无创技术,它可以通过监测血流动力学浓度的变化来检测脑功能的激活。获得的近红外光谱信号通常受到呼吸和心脏收缩引起的生理干扰的污染。采用最小均方算法的自适应滤波方法或基于多距离探头配置的递推最小二乘算法虽然可以提高脑活动诱发反应的质量,但这两种方法都只能去除头部组织浅层的生理干扰。为了克服这一缺点,我们将递归最小二乘自适应滤波方法与最小二乘支持向量机相结合,对头部组织的表层和深层进行生理干扰抑制。基于性能测量的量化结果表明,该方法对诱发血流动力学变化的估计性能优于传统的递推最小二乘法。
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引用次数: 0
Influence of extracerebral layers on estimates of optical properties with continuous wave near infrared spectroscopy: analysis based on multi-layered brain tissue architecture and Monte Carlo simulation. 脑外层对连续波近红外光谱光学特性估计的影响:基于多层脑组织结构和蒙特卡罗模拟的分析。
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2019-01-01 DOI: 10.1080/24699322.2018.1560090
Yan Zhang, Xin Liu, Qisong Wang, Dan Liu, Chunling Yang, Jinwei Sun, P. Rolfe
Continuous wave near-infrared spectroscopy (CW-NIRS) can be used to measure cerebral activity because it is noninvasive, simple and portable. However, the performance of the CW-NIRS is distorted by the presence of extracerebral layer. Change of optical parameters in gray matter layer will then be inappropriately converted into the brain activity response. In the current study, a five-layer structure model constitute of scalp, skull, cerebrospinal fluid, gray matter and white matter is adopted and the mixture of the Intralipid, India ink and agar is applied to fabricate human brain tissue. To simulate optical properties in deep layer due to the brain activity, the absorption coefficients of gray matter are increased by 5%, 10%, 15%, 20%, and 25% relative to the baseline. The NIRS measurement system was designed to detect the changes in the absorption coefficients of the gray matter and quantitatively analyse the influence of the extracerebral layers. Monte Carlo technique is performed to compensate partial volume effect (PVE) introduced by the extracerebral layers. The results of the in-vitro experiments show that the measured absorption coefficients are about 9% of the standard value and the relative error is about 91% due to the extracerebral layers. The influence of the extracerebral layers is suppressed by correcting PVE with Monte Carlo simulations and the average relative error is improved to only about 6% for the whole data set. Therefore, the measurement and analysis of the brain activity could be further strengthened if the anatomic structure of the head could be predicted with Monte Carlo method or other technologies.
连续波近红外光谱(CW-NIRS)具有无创、简单、便携等优点,可用于脑活动测量。然而,由于脑外层的存在,CW-NIRS的性能受到了扭曲。灰质层光学参数的变化会被不恰当地转化为大脑的活动反应。本研究采用由头皮、颅骨、脑脊液、灰质和白质组成的五层结构模型,采用脂质、墨汁和琼脂的混合物制备人脑组织。为了模拟大脑活动引起的深层光学特性,将灰质的吸收系数相对于基线分别提高5%、10%、15%、20%和25%。设计近红外光谱测量系统,检测脑灰质吸收系数的变化,定量分析脑外层对吸收系数的影响。蒙特卡罗技术用于补偿脑外层引入的部分体积效应。体外实验结果表明,测得的吸收系数约为标准值的9%,受脑外层的影响,相对误差约为91%。通过蒙特卡罗模拟校正PVE,抑制了脑外层的影响,使整个数据集的平均相对误差提高到仅6%左右。因此,如果能够利用蒙特卡罗方法或其他技术对头部的解剖结构进行预测,可以进一步加强对大脑活动的测量和分析。
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引用次数: 0
A sensorless force-feedback system for robot-assisted laparoscopic surgery. 用于机器人辅助腹腔镜手术的无传感器力反馈系统。
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2019-01-01 DOI: 10.1080/24699322.2018.1560084
Baoliang Zhao, C. Nelson
The existing surgical robots for laparoscopic surgery offer no or limited force feedback, and there are many problems for the traditional sensor-based solutions. This paper builds a teleoperation surgical system and validates the effectiveness of sensorless force feedback. The tool-tissue interaction force at the surgical grasper tip is estimated using the driving motor's current, and fed back to the master robot with a position-force bilateral control algorithm. The stiffness differentiation experiment and tumor detection experiment were conducted. In the stiffness differentiation experiment, 43 out of 45 pairs of ranking relationships were identified correctly, yielding a success rate of 96%. In the tumor detection experiment, 4 out of 5 participants identified the correct tumor location with force feedback, yielding a success rate of 80%. The proposed sensorless force-feedback system for robot-assisted laparoscopic surgery can help surgeons regain tactile information and distinguish between the healthy and cancerous tissue.
现有的腹腔镜手术机器人不提供或只提供有限的力反馈,传统的基于传感器的解决方案存在许多问题。本文构建了一个远程手术系统,并验证了无传感器力反馈的有效性。利用驱动电机的电流估计手术刀刀尖处的工具-组织相互作用力,并通过位置-力双边控制算法反馈给主机器人。进行了刚度鉴别实验和肿瘤检测实验。在刚度区分实验中,45对排序关系中有43对被正确识别,成功率为96%。在肿瘤检测实验中,5名参与者中有4人通过力反馈识别出了正确的肿瘤位置,成功率为80%。提出的用于机器人辅助腹腔镜手术的无传感器力反馈系统可以帮助外科医生恢复触觉信息并区分健康组织和癌变组织。
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引用次数: 1
Unsupervised binocular depth prediction network for laparoscopic surgery. 腹腔镜手术无监督双目深度预测网络。
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2019-01-01 DOI: 10.1080/24699322.2018.1560082
Ke Xu, Zhiyong Chen, F. Jia
Minimally invasive surgery (MIS) is characterized by less trauma, shorter recovery time, and lower postoperative infection rate. The two-dimensional (2D) laparoscopic imaging lacks depth perception and does not provide quantitative depth information, thereby limiting precise and complex surgical operations. Three-dimensional (3D) laparoscopic imaging provides surgeons depth perception. This study aims to 3D reconstruction of the surgical scene based on the disparity map generated by the depth estimation algorithm. An unsupervised learning autoencoder method was proposed to calculate the accurate disparity with a 101-layer residual convolutional network. The loss function included three parts: left-right consistency loss, structure similarity loss, and reconstruction error loss, the combination can improve reconstruction accuracy and robustness. The method was validated on a Hamlyn Center Laparoscopic/Endoscopic Video Dataset. The structural similarity index (SSIM) is 0.8349 ± 0.0523 and the peak signal-to-noise ratio (PSNR) is 14.4957 ± 1.9676. The depth prediction network has high accuracy and robustness. The average time to produce each disparity map is about 16 ms. The experimental result shows that the proposed depth estimation method can offer dense disparity map, and can meet surgical real-time requirement. Future work will focus on network structure optimization and loss function design, transfer learning to improve the robustness and accuracy further.
微创手术具有创伤小、恢复时间短、术后感染率低等特点。二维(2D)腹腔镜成像缺乏深度感知,不能提供定量的深度信息,从而限制了精确和复杂的外科手术。三维(3D)腹腔镜成像为外科医生提供深度感知。本研究旨在基于深度估计算法生成的视差图对手术场景进行三维重建。提出了一种基于101层残差卷积网络的无监督学习自编码器方法来精确计算视差。损失函数包括左右一致性损失、结构相似度损失和重构误差损失三部分,结合使用可以提高重构精度和鲁棒性。该方法在Hamlyn中心腹腔镜/内窥镜视频数据集上进行了验证。结构相似指数(SSIM)为0.8349±0.0523,峰值信噪比(PSNR)为14.4957±1.9676。该深度预测网络具有较高的精度和鲁棒性。生成每个视差图的平均时间约为16毫秒。实验结果表明,所提出的深度估计方法能够提供密集的视差图,满足手术实时性的要求。未来的工作将集中在网络结构优化、损失函数设计、迁移学习等方面,进一步提高鲁棒性和准确性。
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引用次数: 0
A non-contact interactive stereo display system for exploring human anatomy. 一种用于探索人体解剖的非接触式交互式立体显示系统。
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2019-01-01 DOI: 10.1080/24699322.2018.1560083
Ziteng Liu, Wenpeng Gao, Yu Sun, Yixian Su, Jiahua Zhu, Lubing Xu, Yili Fu
Stereoscopic display based on Virtual Reality (VR) can facilitate doctors to observe the 3 D virtual anatomical models with the depth cues, assist them in intuitively investigating the spatial relationship between different anatomical structures without mental imagination. However, there is few input device can be used in controlling the virtual anatomical models in the sterile operating room. This paper presents a cost-effective VR application system for demonstration of 3 D virtual anatomical models with non-contact interaction and stereo display. The system is integrated with hand gesture interaction and voice interaction to achieve non-contact interaction. Hand gesture interaction is implemented based on a Leap Motion controller mounted on the Oculus Rift DK2. Voice is converted into operation using Bing Speech for English language and Aitalk for Chinese language, respectively. A local relationship database is designed to record the anatomical terminologies to speech recognition engine to query these uncommon words. The hierarchical nature of these terminologies is also recorded in a tree structure. In the experiments, ten participants were asked to perform the evaluation on the proposed system. The results show that our system is more efficient than traditional interactive manner and verify the feasibility and practicability in the sterile operating room.
基于虚拟现实(VR)的立体显示技术可以方便医生借助深度线索观察三维虚拟解剖模型,帮助医生无需想象,直观地了解不同解剖结构之间的空间关系。然而,无菌手术室中能够控制虚拟解剖模型的输入设备很少。提出了一种具有非接触交互和立体显示功能的三维虚拟解剖模型展示应用系统。该系统集成了手势交互和语音交互,实现非接触交互。手势交互是基于安装在Oculus Rift DK2上的Leap Motion控制器实现的。语音转换为操作,英文使用Bing Speech,中文使用Aitalk。设计了一个局部关系数据库,将解剖术语记录到语音识别引擎中,以查询这些不常见的词汇。这些术语的层次性质也记录在树形结构中。在实验中,10名参与者被要求对所提出的系统进行评估。结果表明,该系统比传统的交互方式更高效,验证了该系统在无菌手术室的可行性和实用性。
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引用次数: 0
Minimally invasive surgical techniques for the therapy of far lateral disc herniation in middle-aged and elderly patients. 微创手术技术治疗中老年远外侧椎间盘突出症。
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2019-01-01 DOI: 10.1080/24699322.2018.1560096
Weijian Ren, Yu Chen, Liangbi Xiang
To examine the clinical results of different minimally invasive techniques for the therapy of far lateral disc herniation in middle-aged and elderly patients. Percutaneous endoscopic lumbar discectomy, MIS-TLIF combined with contralateral translaminar screw and MIS-TLIF combined with bilateral pedicle screws were evaluated via a retrospective chart review. Data from 74 consecutive middle-aged and elderly patients with far lateral disc herniation were analyzed. All patients underwent surgery; 19 with PELD, 24 with MIS-TLIF CTS, and 31 with MIS-TLIF BPS. Clinical data included the length of the incision, duration of the operation, blood loss, hospitalization time, operation cost, recurrence rate, and fusion rate. Preoperative and postoperative patient outcomes including the VAS, ODI scores and MacNab criteria were assessed and recorded. The mean follow-up time was 26.4 months (range from 14 to 46 months). Compared with the internal fixation groups, the length of the incision, duration of operation, blood loss, and hospitalization time were obviously lower in the PELD group. The difference in operation cost among the three methods was statistically significant. The postoperative VAS scores for LBP and LP decreased significantly as compared with those recorded preoperatively. The postoperative ODI scores were lower than those recorded preoperatively. MacNab criteria rating excellent, good and fair results were in 27, 37 and 10 patients, respectively. PELD, MIS-TLIF CTS, and MIS-TLIF BPS are all effective minimally invasive techniques for the therapy of single segment far lateral lumbar disc herniation in middle-aged and elderly patients. PELD had a shorter operation time and less surgical trauma, being a less invasive and more economical method; however, there was no recurrence of disc herniation after fixation. Compared with MIS-TLIF BPS, MIS-TLIF CTS obtained a similar fusion rate and certain costs were saved.
目的探讨不同微创技术治疗中老年椎间盘远外侧突出症的临床效果。经皮内镜下腰椎间盘切除术、MIS-TLIF联合对侧椎板间螺钉和MIS-TLIF联合双侧椎弓根螺钉通过回顾性图表复习进行评估。本文分析了74例中老年远外侧椎间盘突出症患者的资料。所有患者均接受手术治疗;19例为PELD, 24例为MIS-TLIF CTS, 31例为MIS-TLIF BPS。临床资料包括切口长度、手术时间、出血量、住院时间、手术费用、复发率、融合率。评估并记录术前和术后患者预后,包括VAS评分、ODI评分和MacNab标准。平均随访时间26.4个月(14 ~ 46个月)。与内固定组比较,PELD组切口长度、手术时间、出血量、住院时间均明显低于内固定组。三种方法的手术费用差异有统计学意义。与术前相比,术后腰痛和腰痛VAS评分明显下降。术后ODI评分低于术前。根据MacNab标准,分别有27例、37例和10例患者获得优秀、良好和公平的结果。PELD、MIS-TLIF CTS和MIS-TLIF BPS都是治疗中老年单节段远外侧腰椎间盘突出症的有效微创技术。PELD手术时间短,手术创伤小,创伤小,经济实惠;然而,固定后没有复发的椎间盘突出。与MIS-TLIF BPS相比,MIS-TLIF CTS获得了相似的融合率,并节省了一定的成本。
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引用次数: 0
Three-dimensional fluoroscopic navigation-assisted surgery for tumors in patients with tumor-induced osteomalacia in the bones 三维透视导航辅助肿瘤手术治疗肿瘤引起的骨软化症
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2017-01-01 DOI: 10.1080/24699322.2017.1282044
Hiroshi Kobayashi, T. Akiyama, Tomotake Okuma, Yusuke Shinoda, H. Oka, N. Ito, S. Fukumoto, Sakae Tanaka, H. Kawano
Abstract Purpose: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome usually caused by phosphaturic mesenchymal tumors. Segmental resection has been recommended for these tumors in the bones because curettage was found to be associated with a high local recurrence rate. Navigation-assisted surgery provides radiological information to guide the surgeon during surgery. No previous study has reported on the efficacy of navigation-assisted surgery for tumors in patients with TIO. Therefore, the present study aimed to evaluate the efficacy of navigation-assisted surgery for tumors in patients with TIO. Methods: The study included seven patients with TIO who were treated between January 2003 and December 2014 at our hospital. All patients underwent surgical treatment with or without the use of a 3-dimensional (3D) fluoroscopy-based navigation system. The laboratory data and oncological outcomes were evaluated. Results: The follow-up period was 8–128 months. The tumors were located at the femur (n = 4), ischium, spine and ilium (n = 1). Of the seven patients, five underwent navigation-assisted surgery and two underwent surgery without navigation assistance. In the two patients who underwent surgery without navigation assistance, a complete cure was not obtained and osteomalacia did not resolve. One of these two patients and the other five patients who underwent navigation-assisted surgery, one patient had incomplete resection due to massive invasion of the tumor into the spinal canal, but five patients achieved complete excision and recovered from osteomalacia. Conclusions: Navigation-assisted surgery using a 3D fluoroscopy-based navigation system is effective for tumors in patients with TIO.
摘要目的:肿瘤诱导骨软化症(TIO)是一种罕见的副肿瘤综合征,通常由磷质间充质肿瘤引起。部分切除已被推荐用于骨内肿瘤,因为发现刮除与高局部复发率相关。导航辅助手术提供放射学信息来指导外科医生进行手术。以前没有研究报道导航辅助手术治疗TIO患者肿瘤的疗效。因此,本研究旨在评估导航辅助手术治疗TIO患者肿瘤的疗效。方法:选取2003年1月至2014年12月在我院治疗的7例TIO患者作为研究对象。所有患者都接受了手术治疗,有或没有使用基于三维(3D)透视的导航系统。对实验室数据和肿瘤结果进行评估。结果:随访8 ~ 128个月。肿瘤位于股骨(n = 4)、坐骨、脊柱和髂骨(n = 1)。在7名患者中,5名接受了导航辅助手术,2名接受了没有导航辅助的手术。在没有导航辅助的情况下进行手术的两名患者,没有得到完全治愈,骨软化也没有解决。其中1例患者和另外5例患者行导航辅助手术,1例患者因肿瘤大量侵入椎管而未完全切除,但5例患者完全切除并从骨软化症中恢复。结论:基于三维透视的导航系统导航辅助手术治疗TIO患者的肿瘤是有效的。
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引用次数: 13
Erratum 勘误
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2017-01-01 DOI: 10.1080/24699322.2016.1275268
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引用次数: 0
Efficacy of a novel iPod-based navigation system compared to traditional navigation system in total knee arthroplasty 基于ipod的新型导航系统与传统导航系统在全膝关节置换术中的疗效比较
IF 2.1 4区 医学 Q3 SURGERY Pub Date : 2017-01-01 DOI: 10.1080/24699322.2016.1276630
A. Mullaji, G. Shetty
Abstract Background: This prospective study aimed to verify the efficacy of a novel, hand-held, iPod-based navigation system in comparison to traditional navigation system for total knee arthroplasty (TKA). Methods: Limb alignment, tibial and distal femoral bone cut thickness and plane were recorded intraoperatively using both iPod-based and traditional navigation system in 36 knees undergoing primary TKAs. Results: Intraoperatively, the iPod-based navigation system showed good to excellent correlation and reliability for tibial and distal femoral bone cut thickness, plane of the femoral cut and limb alignment when compared to the traditional navigation system. Conclusions: Despite its quick registration feature, the iPod-based system has an efficacy similar to traditional navigation system and is a positive step towards making navigation systems for TKA more compact, user-friendly, time and cost-effective.
摘要背景:本前瞻性研究旨在验证新型手持iPod导航系统与传统导航系统在全膝关节置换术(TKA)中的疗效。方法:在36例接受TKA的膝关节患者中,使用基于iPod和传统导航系统在手术中记录肢体对齐、胫骨和股骨远端骨切割厚度和平面。结果:术中,与传统导航系统相比,基于iPod的导航系统在胫骨和股骨远端骨切口厚度、股骨切口平面和肢体对齐方面显示出良好的相关性和可靠性。结论:尽管具有快速注册功能,但基于iPod的系统具有与传统导航系统类似的功效,是朝着使TKA导航系统更紧凑、用户友好、时间和成本效益迈出的积极一步。
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引用次数: 3
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Computer Assisted Surgery
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