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The role of the precuneus and posterior cingulate cortex in the neural routes to action. 楔前皮层和后扣带回皮层在行动神经通路中的作用。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2019-10-01 Epub Date: 2019-01-04 DOI: 10.1080/24699322.2018.1557903
Zijian Wang, Liu Fei, Yaoru Sun, Jie Li, Fang Wang, Zheng Lu

Neural substrates of action to the object or this specific direct route, however, remain unclear, especially for the connection from the visual pathway to the motor cortex. The study examined this issue by conducting an fMRI experiment, in which two action generation tasks involving pictures of real objects (PA) and the object's nouns (NA) were used, with pictures naming (PN) and covert noun reading (NR) being the control tasks. The result showed that the model predefined for the PCC and precuneus connecting IPL to the posterior-medial frontal cortex dominated over the others (with 0.45 probability), suggesting that the PCC and the precuneus locate at the neural substrates of action to the object. Furthermore, a feasibility study suggests that the neural pathway composed of the V3/MT, precuneus, PCC, and PM (premotor cortex) forms the direct route from perception to action, which also links to the dorsal pathway so that the perception of objects bypasses the semantic ventral pathway and then directly cues actions via the affordance.

然而,从视觉通路到运动皮层这一特定直接路径的神经基底仍不清楚。该研究通过进行fMRI实验来探讨这一问题,实验中使用了两个动作生成任务,分别涉及真实物体的图片(PA)和物体的名词(NA),而图片命名(PN)和隐蔽名词阅读(NR)则是对照任务。结果表明,连接 IPL 与后内侧额叶皮层的 PCC 和楔前丘的预设模型优于其他模型(概率为 0.45),表明 PCC 和楔前丘位于对物体行动的神经底层。此外,一项可行性研究表明,由 V3/MT、楔前区、PCC 和 PM(前运动皮层)组成的神经通路构成了从感知到行动的直接路径,该路径还与背侧通路相连,因此对物体的感知绕过了语义腹侧通路,然后直接通过负担能力来提示行动。
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引用次数: 0
A sensorless force-feedback system for robot-assisted laparoscopic surgery. 用于机器人辅助腹腔镜手术的无传感器力反馈系统。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2019-10-01 Epub Date: 2019-01-21 DOI: 10.1080/24699322.2018.1557887
Baoliang Zhao, Carl A Nelson

The existing surgical robots for laparoscopic surgery offer no or limited force feedback, and there are many problems for the traditional sensor-based solutions. This paper builds a teleoperation surgical system and validates the effectiveness of sensorless force feedback. The tool-tissue interaction force at the surgical grasper tip is estimated using the driving motor's current, and fed back to the master robot with position-force bilateral control algorithm. The stiffness differentiation experiment and tumor detection experiment were conducted. In the stiffness differentiation experiment, 43 out of 45 pairs of ranking relationships were identified correctly, yielding a success rate of 96%. In the tumor detection experiment, 4 out of 5 participants identified the correct tumor location with force feedback, yielding a success rate of 80%. The proposed sensorless force-feedback system for robot-assisted laparoscopic surgery can help surgeons regain tactile information and distinguish between the healthy and cancerous tissue.

现有的腹腔镜手术机器人不提供力反馈或提供的力反馈有限,传统的基于传感器的解决方案存在很多问题。本文构建了一个远程操作手术系统,并验证了无传感器力反馈的有效性。利用驱动电机的电流估算手术抓手尖端的工具-组织相互作用力,并通过位置-力双边控制算法反馈给主机器人。进行了刚度分化实验和肿瘤检测实验。在刚度区分实验中,45 对排序关系中有 43 对被正确识别,成功率为 96%。在肿瘤检测实验中,5 名参与者中有 4 人通过力反馈识别出了正确的肿瘤位置,成功率为 80%。所提出的用于机器人辅助腹腔镜手术的无传感器力反馈系统可以帮助外科医生重新获得触觉信息,并区分健康组织和癌组织。
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引用次数: 0
Influence of extracerebral layers on estimates of optical properties with continuous wave near infrared spectroscopy: analysis based on multi-layered brain tissue architecture and Monte Carlo simulation. 脑外层对连续波近红外光谱光学特性估算的影响:基于多层脑组织结构和蒙特卡罗模拟的分析。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2019-10-01 Epub Date: 2019-01-24 DOI: 10.1080/24699322.2018.1557902
Yan Zhang, Xin Liu, Qisong Wang, Dan Liu, Chunling Yang, Jinwei Sun

Continuous wave near-infrared spectroscopy (CW-NIRS) can be used to measure cerebral activity because it is noninvasive, simple and portable. However, the performance of the continuous wave near-infrared spectroscopy is distorted by the presence of extracerebral layer. Change of optical parameters in gray matter layer will then be inappropriately converted into the brain activity response. In the current study, a five-layer structure model constitute of scalp, skull, cerebrospinal fluid, gray matter and white matter, have been applied to fabricate human brain tissue. The phantom is made by the mixture of the Intralipid, India ink and agar. The optical parameters of gray matter layer can be flexibly adjusted to simulate the change of the deep brain tissue. The near infrared optical measurement system was designed to detect the changes in the absorption coefficients of the gray matter and quantitative analyze the influence of the extracerebral layers. Monte Carlo technique for the equivalent multi-layered brain tissue models is then performed to compensate partial volume effect introduced by the extracerebral layers. The results of the experiments suggested that the extracerebral layers influence the measurement and the influence of the extracerebral layers can be suppressed by correcting partial volume effect using Monte Carlo simulations.

连续波近红外光谱仪(CW-NIRS)可用于测量大脑活动,因为它具有无创、简单和便携的特点。然而,连续波近红外光谱仪的性能会因大脑外层的存在而失真。灰质层的光学参数变化会被不恰当地转换为大脑活动反应。目前的研究采用了由头皮、头骨、脑脊液、灰质和白质构成的五层结构模型来制作人脑组织。该模型由 Intralipid、印度墨水和琼脂混合制成。灰质层的光学参数可灵活调整,以模拟深层脑组织的变化。设计的近红外光学测量系统可检测灰质吸收系数的变化,并定量分析脑外层的影响。然后对等效多层脑组织模型进行蒙特卡洛技术处理,以补偿脑外层带来的部分体积效应。实验结果表明,脑外层对测量结果有影响,通过蒙特卡洛模拟修正部分体积效应可以抑制脑外层的影响。
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引用次数: 0
A novel technique for analysing histogram equalized medical images using superpixels. 一种利用超像素均衡化医学图像的直方图分析新技术。
IF 2.1 4区 医学 Q1 Medicine Pub Date : 2019-10-01 Epub Date: 2019-01-28 DOI: 10.1080/24699322.2018.1560100
Li Yao, Sohail Muhammad

We present a novel technique to distinguish between an original image and its histogram equalized version. Histogram equalization and superpixel segmentation such as SLIC (simple linear iterative clustering) are very popular image processing tools. Based on these two concepts, we introduce a method for finding whether an image (grayscale) is histogram equalized or not. Because sometimes we see images that look visually similar but they are actually processed or changed by some image enhancement process such as histogram equalization. We can merely infer whether the image is dark, bright or has a small dynamic range. Moreover, we also compare the result of SLIC superpixels with three other superpixel segmentation algorithms namely, quick shift, watersheds, and Felzenszwalb's segmentation algorithm.

我们提出了一种新的技术来区分原始图像和其直方图均衡化版本。直方图均衡化和超像素分割如SLIC(简单线性迭代聚类)是非常流行的图像处理工具。基于这两个概念,我们引入了一种检测图像(灰度)是否为直方图均衡化的方法。因为有时我们看到的图像看起来很相似,但实际上它们被处理或改变了一些图像增强过程,比如直方图均衡化。我们只能推断图像是暗的、亮的还是动态范围小。此外,我们还将SLIC超像素的分割结果与其他三种超像素分割算法(quick shift、watershed和Felzenszwalb分割算法)进行了比较。
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引用次数: 9
A non-contact interactive stereo display system for exploring human anatomy. 用于探索人体解剖学的非接触式互动立体显示系统。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2019-10-01 Epub Date: 2019-02-11 DOI: 10.1080/24699322.2018.1557899
Ziteng Liu, Wenpeng Gao, Yu Sun, Yixian Su, Jiahua Zhu, Lubing Xu, Yili Fu

Stereoscopic display based on Virtual Reality (VR) can facilitate clinicians observing 3 D anatomical models with the depth cue which lets them understand the spatial relationship between different anatomical structures intuitively. However, there are few input devices available in the sterile field of the operating room for controlling 3 D anatomical models. This paper presents a cost-effective VR application for stereo display of 3 D anatomical models with non-contact interaction. The system is integrated with hand gesture interaction and voice interaction to achieve non-contact interaction. Hand gesture interaction is based on Leap Motion. Voice interaction is implemented based on Bing Speech for English language and Aitalk for Chinese language. A local database is designed to record the anatomical terminologies organized in a tree structure, and provided to the speech recognition engine for querying these uncommon words. Ten participants were asked to practice the proposed system and compare it with the common interactive manners. The results show that our system is more efficient than the common interactive manner and prove the feasibility and practicability of the proposed system used in the sterile field.

基于虚拟现实技术(VR)的立体显示技术可以帮助临床医生通过深度线索观察三维解剖模型,从而直观地了解不同解剖结构之间的空间关系。然而,在手术室的无菌环境中,可用于控制 3 D 解剖模型的输入设备很少。本文介绍了一种经济高效的 VR 应用程序,用于以非接触式交互方式立体显示 3 D 解剖模型。该系统集成了手势交互和语音交互,以实现非接触式交互。手势交互基于 Leap Motion。语音交互基于必应语音(英语)和 Aitalk(中文)实现。设计了一个本地数据库,以树形结构记录解剖术语,并提供给语音识别引擎,用于查询这些不常用的词汇。十名参与者被要求练习所提议的系统,并将其与常见的互动方式进行比较。结果表明,我们的系统比常见的交互式方式更有效,证明了在无菌领域使用拟议系统的可行性和实用性。
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引用次数: 0
A targeting method for robot-assisted percutaneous needle placement under fluoroscopy guidance. 透视引导下机器人辅助经皮置入针的瞄准方法。
IF 1.5 4区 医学 Q3 SURGERY Pub Date : 2019-10-01 Epub Date: 2019-01-28 DOI: 10.1080/24699322.2018.1557907
Zhonghao Han, Keyi Yu, Lei Hu, Weishi Li, Huilin Yang, Minfeng Gan, Na Guo, Biao Yang, Hongsheng Liu, Yuhan Wang

Minimally invasive procedures are rapidly growing in popularity thanks to advancements in medical robots, visual navigation and space registration techniques. This paper presents a precise and efficient targeting method for robot-assisted percutaneous needle placement under C-arm fluoroscopy. In this method, a special end-effector was constructed to perform fluoroscopy calibration and robot to image-space registration simultaneously. In addition, formulations were given to compute the movement of robot targeting and evaluate targeting accuracy using only one X-ray image. With these techniques, radiation exposure and operation time were reduced significantly compared to other commonly used methods. A pre-clinical experiment showed that the maximum angle error was 0.94° and the maximum position error of a target located 80mm below the end-effector was 1.31mm. And evaluation of the system in a robot-assisted pedicle screws placement surgery has justified the accuracy and reliability of proposed method in clinical applications.

由于医疗机器人、视觉导航和空间注册技术的进步,微创手术正迅速普及。本文介绍了一种在 C 臂透视下机器人辅助经皮穿刺置针的精确高效瞄准方法。在该方法中,构建了一种特殊的末端执行器,可同时执行透视校准和机器人与图像空间的配准。此外,还给出了计算机器人瞄准运动的公式,并仅使用一张 X 射线图像来评估瞄准的准确性。与其他常用方法相比,这些技术大大减少了辐射量和操作时间。临床前实验表明,最大角度误差为 0.94°,位于末端执行器下方 80 毫米处的目标的最大位置误差为 1.31 毫米。该系统在机器人辅助椎弓根螺钉置入手术中的评估证明了所提方法在临床应用中的准确性和可靠性。
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引用次数: 0
Synchronization control of pulsatile ventricular assist devices by combination usage of different physiological signals. 不同生理信号联合作用下脉动性心室辅助装置的同步控制。
IF 2.1 4区 医学 Q1 Medicine Pub Date : 2019-10-01 Epub Date: 2019-02-14 DOI: 10.1080/24699322.2018.1560089
Xinghui Li, Lunchao Zhong, Lin Luo, Shidong Zhu, Kai Ni, Qian Zhou, Bibo Yang, Xiaohao Wang

Three different types of synchronous control methods based on physiological parameters, electrocardiogram (ECG) and fixed systole, ECG and aortic pressure, and ECG and phonocardiogram (PCG) were used to trigger a proposed intra-ventricular assist device (iVAD). The ECG, aortic pressure, and PCG were processed, respectively, and featured characteristics were extracted to trigger the iVAD-experimented in vitro circulation system in the laboratory. The data showed that all three types of synchronous control methods produced trigger pulses synchronously and that the iVAD synchronously beat with the native heart. The multi-cycle data demonstrated that the synchronous delay time of the proposed iVAD during systole and diastole was separately stabilized at a certain time. This study showed that the combination of three synchronization methods can be applied to the iVAD to improve the reliability of synchronization.

采用基于生理参数、心电图(ECG)和固定收缩压、心电图和主动脉压、心电图和心音图(PCG)的三种不同类型的同步控制方法触发拟议的室内辅助装置(iVAD)。分别对心电图、主动脉压、PCG进行处理,提取特征特征触发实验室体外循环系统ivad实验。数据显示,所有三种同步控制方法都能同步产生触发脉冲,并且iVAD与原生心脏同步跳动。多周期数据表明,所提出的iVAD在收缩期和舒张期的同步延迟时间分别稳定在一定时间。本研究表明,三种同步方法的组合可应用于iVAD,以提高同步的可靠性。
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引用次数: 3
Spinal biomechanics modeling and finite element analysis of surgical instrument interaction. 脊柱生物力学建模及手术器械相互作用的有限元分析。
IF 2.1 4区 医学 Q1 Medicine Pub Date : 2019-10-01 Epub Date: 2019-01-28 DOI: 10.1080/24699322.2018.1560086
Weixing Guan, Yu Sun, Xiaozhi Qi, Ying Hu, Chunguang Duan, Huiren Tao, Xiaojun Yang

When the spinal surgery robot assists the surgeon perform the surgery, the patient is prone on the operating table. However, due to the force of the surgical instruments on the spine, there is a corresponding deformation in the surgical field, which affects the accuracy of the operation. In order to improve the accuracy and safety of the operation, this paper reconstructs the three-dimensional model of the lumbar spine which includes the vertebral body and the intervertebral disc based on the CT scan data, and then the lumbar spine is analyzed by the finite element method. The mathematical model of the relationship between force and displacement is established by using response surface methodology based on the simulation results. After that, the position control system is constructed based on the mathematical model. Through the simulation of the control system, the trajectory curve of the end of the manipulator is compared and the validity of the mathematical model is verified.

当脊柱手术机器人协助外科医生进行手术时,患者俯卧在手术台上。然而,由于手术器械对脊柱的作用力,在手术场中会产生相应的变形,影响手术的准确性。为了提高手术的准确性和安全性,本文基于CT扫描数据重建了包括椎体和椎间盘在内的腰椎三维模型,然后采用有限元法对腰椎进行分析。基于仿真结果,采用响应面法建立了力与位移关系的数学模型。然后,基于数学模型构建了位置控制系统。通过对控制系统的仿真,对比了机械手末端的轨迹曲线,验证了数学模型的有效性。
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引用次数: 8
Nonlinear ultrasonic imaging in pulse-echo mode using Westervelt equation: a preliminary research 基于Westervelt方程的脉冲回波模式非线性超声成像初步研究
IF 2.1 4区 医学 Q1 Medicine Pub Date : 2019-09-24 DOI: 10.1080/24699322.2019.1649065
Wuxuan Chen, Peng Wang, Zhihong Zhang, Xudong Deng, C. Zhang, Shenggen Ju
Abstract Acoustic nonlinear parameter β, was of great interest in tissue characterization in recent years. Nonlinear imaging methods have been reported to provide improved spatial and contrast resolution. We introduce a nonlinear imaging method derived from nonlinear wave equation based on Gaussian-form solution assumption, which can be applied in pulse-echo mode on diagnostic ultrasound. Through making the use of two pulse transmission, only nonlinear effects are reserved and other effects like scattering, diffraction and linear attenuation can be eliminated. For validation of this method a set of simulation results are generated with a nonlinear simulator. Simulated images also indicate that our method clearly describes the spatial distribution of B/A in the medium.
摘要近年来,声学非线性参数β在组织表征中引起了极大的兴趣。据报道,非线性成像方法提供了改进的空间分辨率和对比度分辨率。我们介绍了一种基于高斯形式解假设的非线性波动方程的非线性成像方法,该方法可以应用于诊断超声的脉冲回波模式。通过使用双脉冲传输,只保留了非线性效应,可以消除散射、衍射和线性衰减等其他效应。为了验证该方法,使用非线性模拟器生成了一组模拟结果。模拟图像还表明,我们的方法清楚地描述了B/A在介质中的空间分布。
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引用次数: 5
Notice of Duplicate Publication 复本公告
IF 2.1 4区 医学 Q1 Medicine Pub Date : 2019-09-16 DOI: 10.1080/24699322.2019.1646921
(2019). Notice of Duplicate Publication. Computer Assisted Surgery: Vol. 24, Advances in Minimally Invasive Surgery and Clinical Measurement. Guest Editors: Chengyu Liu & Lung-kwang Pan, pp. 184-185.
(2019)。副本出版通知。计算机辅助手术:第24卷,微创手术和临床测量的进展。特邀编辑:刘成玉、潘龙光,页184-185。
{"title":"Notice of Duplicate Publication","authors":"","doi":"10.1080/24699322.2019.1646921","DOIUrl":"https://doi.org/10.1080/24699322.2019.1646921","url":null,"abstract":"(2019). Notice of Duplicate Publication. Computer Assisted Surgery: Vol. 24, Advances in Minimally Invasive Surgery and Clinical Measurement. Guest Editors: Chengyu Liu & Lung-kwang Pan, pp. 184-185.","PeriodicalId":56051,"journal":{"name":"Computer Assisted Surgery","volume":null,"pages":null},"PeriodicalIF":2.1,"publicationDate":"2019-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138530079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Computer Assisted Surgery
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