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Using learning-by-concordance to develop reasoning in epistaxis management with online feedback: A pilot study. 通过在线反馈,利用 "边学边做 "培养鼻衄处理中的推理能力:试点研究。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241274583
Benjamin Verillaud, Marine Veleur, Romain Kania, Ivry Zagury-Orly, Nicolas Fernandez, Bernard Charlin

Background: Epistaxis is a recurring cause for referral to emergency departments. Its management can be complex; hence, it is critical to provide appropriate support to Otolaryngology-Head and Neck Surgery (OHNS) residents to develop clinical reasoning skills to manage such cases. Learning-by-Concordance (LbC) is a recently developed educational tool that encourages learners to think through simulated clinical scenarios. A panel of ENTs provides insightful feedback to residents, reflecting a diversity of opinions about practice. Our study aimed to assess LbC's feasibility and perceived value for training OHNS residents in epistaxis management.

Methods: In this qualitative study, three OHNS surgeons, including two faculty members and one resident, wrote the LbC scenarios. The LbC tool was made available to participants through an online platform. A panel of four OHNS faculty provided feedback on answers to LbC questions. Otolaryngology-Head and Neck Surgery residents participated and provided their opinion on the value of this educational tool through an online questionnaire.

Results: A total of 10 one-hour sessions were required to create and upload the training tool. To provide insightful feedback embedded in the learning tool, the four panelists needed 60 min each. Of the 37 participating residents, 25 (68%) completed the training. Overall satisfaction was high: 88% appreciated the training method, and 92% wanted to use this type of training again. Most residents felt the training enabled them to improve their clinical reasoning when encountering a patient with epistaxis (92%) and their knowledge about epistaxis (96%).

Conclusion: Findings suggest that OHNS residents could benefit from clinical reasoning exercises with panelist feedback using the LbC approach for clinical presentations that require complex approaches to manage conditions such as epistaxis.

背景:鼻衄是急诊科的常见病。其处理过程可能很复杂;因此,为耳鼻咽喉头颈外科(OHNS)住院医师提供适当的支持,培养他们处理此类病例的临床推理技能至关重要。协作学习(LbC)是最近开发的一种教育工具,它鼓励学员通过模拟临床情景进行思考。耳鼻喉科专家小组会向住院医师提供有见地的反馈意见,反映出对实践的不同看法。我们的研究旨在评估 LbC 在培训耳鼻喉科住院医师处理鼻衄方面的可行性和感知价值:在这项定性研究中,包括两名教师和一名住院医师在内的三名内科外科医生编写了 LbC 情景。LbC 工具通过在线平台提供给参与者。由四位耳鼻喉科外科医生组成的小组就LbC问题的答案提供反馈意见。耳鼻咽喉头颈外科住院医师也参与其中,并通过在线问卷就这一教育工具的价值发表了意见:结果:创建和上传培训工具共需要 10 个小时的时间。为了在学习工具中提供有见地的反馈意见,四位小组成员每人需要 60 分钟。在 37 名参与培训的住院医师中,25 人(68%)完成了培训。总体满意度很高:88%的人对培训方法表示赞赏,92%的人希望再次使用此类培训。大多数住院医师认为培训提高了他们在遇到鼻衄患者时的临床推理能力(92%)和对鼻衄的认识(96%):研究结果表明,在处理鼻衄等需要复杂方法的临床表现时,使用 LbC 方法进行有小组成员反馈的临床推理练习可使 OHNS 住院医师受益。
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引用次数: 0
Zinc oxide nanoparticles intercalated with porous carbon as a separator coating for improving the stability of lithium metal anodes. 氧化锌纳米粒子与多孔碳的插层作为提高锂金属阳极稳定性的分离涂层。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241276773
Lei Li, Chunhong Hu, Juanjuan Li, Anwei Shen, Shijiang Tan

Metal lithium negative electrodes are considered the "holy grail" of lithium battery negative electrodes due to their ultra-high energy density and low overpotential. However, the arbitrary growth of lithium dendrites during the cycling process hindered its industrialization process. We prepared porous carbon doped with zinc oxide nanoparticles (ZNC-MOF-5) by high-temperature carbonization of MOF-5, and coated ZNC-MOF-5 on the surface of commercial membranes (ZNC-MOF-5@PP). Used to improve the cycling stability of metal lithium negative electrodes. Zinc oxide nanoparticles in ZNC-MOF-5 have good lithium affinity and can promote Li+ deposition. The porous structure with a high specific surface area endows the electrode with high lithium loading capacity, reduces local current density, and obtains a dendrite-free metal lithium negative electrode. The electrochemical cycling performance of Li/Cu batteries indicates that, ZNC-MOF-5@PP. The separator can prevent the growth of dendrites and improve cycling stability, proving that ZNC-MOF-5 can effectively guide the deposition of Li and solve dendrite problems.

金属锂负极因其超高的能量密度和低过电位而被视为锂电池负极的 "圣杯"。然而,锂枝晶在循环过程中的任意生长阻碍了其工业化进程。我们通过高温碳化 MOF-5 制备了掺杂氧化锌纳米颗粒(ZNC-MOF-5)的多孔碳,并将 ZNC-MOF-5 涂覆在商用膜(ZNC-MOF-5@PP)表面。用于提高金属锂负极的循环稳定性。ZNC-MOF-5 中的氧化锌纳米颗粒具有良好的锂亲和性,可促进 Li+ 沉积。高比表面积的多孔结构使电极具有较高的锂负载能力,降低了局部电流密度,并获得了无枝晶的金属锂负极。锂/铜电池的电化学循环性能表明,ZNC-MOF-5@PP.隔膜可以防止枝晶的生长,提高循环稳定性,证明 ZNC-MOF-5 可以有效地引导锂的沉积,解决枝晶问题。
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引用次数: 0
Getting to the root of root-microbe interactions. 从根本上了解根系与微生物之间的相互作用。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241278783
William L King, Regan J Hayward, Marc Goebel, Suzanne M Fleishman, Taryn L Bauerle, Terrence H Bell

Microbial relationships with roots influence many ecosystem functions and nutrient fluxes, including their sometimes-profound effects on plant health and productivity. Fine roots were often classified with a diameter less than 2 mm, but fine roots under that size perform distinct functional roles in the environment. Importantly, two broad functional categories of fine roots are absorptive and transportive, with absorptive fine roots acting as metabolic hotspots for root activity. In two of our recent studies, we have shown that several microbial community characteristics differ between absorptive and transportive fine roots, including composition, abundance, and function, as well as the root metabolome. This highlights a growing recognition within microbial ecology that we must consider fine-scale environmental variability, such as root physiology and morphology, when interpreting microbial patterns. In this commentary, we summarize the findings of our latest article, further speculate on some of these patterns, and suggest future studies for examining decomposition and applying cutting-edge single-cell sequencing techniques.

微生物与根系的关系影响着许多生态系统功能和养分通量,包括它们有时对植物健康和生产力的巨大影响。细根通常以直径小于 2 毫米来分类,但小于 2 毫米的细根在环境中发挥着不同的功能作用。重要的是,细根的两大功能类别是吸收性和运输性,其中吸收性细根是根系活动的代谢热点。在我们最近的两项研究中,我们发现吸收性细根和运输性细根的微生物群落特征有所不同,包括组成、丰度、功能以及根代谢组。这凸显了微生物生态学界日益认识到,在解释微生物模式时,我们必须考虑细微尺度的环境变异,如根的生理和形态。在这篇评论中,我们总结了最新文章的研究结果,进一步推测了其中的一些模式,并提出了今后研究分解和应用尖端单细胞测序技术的建议。
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引用次数: 0
Risk factors for postoperative delirium in patients with cardiac surgery. 心脏手术患者术后谵妄的风险因素。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241266362
Min-Song Kim, Sang-Hee Kim

Purpose: Patients admitted to the intensive care unit (ICU) after cardiac surgery are at high risk of delirium due to a variety of factors. This study aimed to identify the incidence of postoperative delirium in adult patients with cardiac surgery and its risk factors, such as characteristics of subjects, disease and treatment-related, as well as nursing-related characteristics. Methods: The study was performed on adult patients who underwent cardiac surgery at Y University Hospital in D city; a total of 195 patients met the inclusion criteria. Results: The results of this study determined that 67 of 195 adult cardiac surgery patients had postoperative delirium, 53.7% of which occurred in the ICU and 46.3% in the general ward. Risk factors of postoperative delirium were postoperative symptoms of inflammation (odds ratio [OR] = 10.18, p = 0.002), continuous renal replacement therapy application after surgery (OR = 9.05, p = 0.006), postoperative sleep disorder (OR = 8.98, p < 0.001), age (OR = 6.23, p = 0.006), length of stay in the ICU (OR = 3.83, p = 0.031), history of stroke (OR = 3.71, p = 0.033), the number of postoperative catheter retention (OR = 1.53, p = 0.065), Acute Physiology and Chronic Health Evaluation Ⅱ score (OR = 1.12, p = 0.006), and time of operation (OR = 1.01, p = 0.042). Conclusion: This study confirmed that after cardiac surgery, postoperative delirium occurred in patients during their ICU stay and after their transfer to a general ward. Considering that after cardiac surgery ICU-related factors affect the incidence of delirium in the general ward, there is a need for continuous monitoring of ICU-related factors after the patient gets transferred to a general ward.

目的:由于多种因素,心脏手术后入住重症监护室(ICU)的患者极有可能出现谵妄。本研究旨在确定心脏手术成年患者术后谵妄的发生率及其风险因素,如受试者特征、疾病和治疗相关特征以及护理相关特征。研究方法研究对象为在 D 市 Y 大学医院接受心脏手术的成年患者,共有 195 名患者符合纳入标准。结果研究结果显示,195 名成人心脏手术患者中有 67 人出现术后谵妄,其中 53.7% 发生在重症监护室,46.3% 发生在普通病房。术后谵妄的风险因素包括术后炎症症状(比值比 [OR] = 10.18,P = 0.002)、术后持续应用肾脏替代疗法(OR = 9.05,P = 0.006)、术后睡眠障碍(OR = 8.98,P = 0.006)、在重症监护室的住院时间(OR = 3.83,P = 0.031)、中风病史(OR = 3.71,P = 0.033)、术后导管留置次数(OR = 1.53,P = 0.065)、急性生理学和慢性健康评价Ⅱ评分(OR = 1.12,P = 0.006)和手术时间(OR = 1.01,P = 0.042)。结论本研究证实,心脏手术后,患者在入住重症监护室期间和转入普通病房后会出现术后谵妄。考虑到心脏手术后 ICU 相关因素会影响普通病房谵妄的发生率,因此有必要在患者转入普通病房后持续监测 ICU 相关因素。
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引用次数: 0
The role of serum albumin in critical illness, predicting poor outcomes, and exploring the therapeutic potential of albumin supplementation. 血清白蛋白在危重病中的作用,预测不良预后,探索补充白蛋白的治疗潜力。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241274023
Razan Rabi, Reem M Alsaid, Abdelrahman N Matar, Yusuf Dawabsheh, Dina Abu Gaber

Objective: Serum albumin (ALB) plays a vital role in maintaining oncotic pressure and contributing to hemodynamic stability, with low levels associated with adverse outcomes in critically ill patients. This study aimed to assess the association between serum ALB concentrations and poor outcomes and the possible benefits of ALB supplementation.

Methods: A retrospective study involving 300 intensive care unit (ICU) patients. Albumin levels were recorded upon admission and throughout the stay, and patients were categorized based on a cutoff of 2.49 g/dl. The associations between low ALB levels and mortality were assessed using regression analysis. Additionally, it investigated the association of albumin supplementation with patient outcomes and mortality in specific patient populations.

Results: The mean age was 54.9 years, with 68% having sepsis. Patients with low baseline ALB concentrations exhibited higher overall mortality (71% vs. 52%) and 28-day mortality (50% vs. 39%). Adjusted analyses confirmed associations with mortality. Albumin supplementation was administered to 53% of the patients. Its use demonstrated potential benefits, particularly in reducing mortality, when given to specific groups, such as sepsis and hypoalbuminemia patients.

Discussion: The study confirms that low serum albumin levels are strongly associated with higher mortality rates in ICU patients. Albumin supplementation showed potential benefits, particularly in patients with sepsis and low albumin levels. Further analyses explored the dosage-response relationship and identified potential groups that would benefit from albumin supplementation.

Conclusion: Albumin can play a major role in predicting mortality in critically ill patients. Moreover, ALB supplementation may improve survival, especially in resource-limited settings. Future research should refine protocols through clinical trials for optimal survival in critically ill patients.

目的:血清白蛋白(ALB)在维持肿瘤压和血液动力学稳定方面发挥着重要作用,低水平的ALB与重症患者的不良预后有关。本研究旨在评估血清白蛋白浓度与不良预后之间的关系,以及补充白蛋白可能带来的益处:这项回顾性研究涉及 300 名重症监护病房(ICU)患者。研究记录了患者入院时和整个住院期间的白蛋白水平,并根据 2.49 g/dl 的临界值对患者进行了分类。通过回归分析评估了低 ALB 水平与死亡率之间的关系。此外,该研究还调查了白蛋白补充与特定患者群体的预后和死亡率之间的关系:平均年龄为 54.9 岁,68% 的患者患有败血症。基线白蛋白浓度较低的患者总死亡率(71% 对 52%)和 28 天死亡率(50% 对 39%)较高。调整分析证实了与死亡率的关系。53%的患者服用了白蛋白补充剂。对特定人群,如脓毒症和低白蛋白血症患者补充白蛋白有潜在益处,尤其是在降低死亡率方面:讨论:该研究证实,血清白蛋白水平低与重症监护病房患者死亡率较高密切相关。补充白蛋白显示出潜在的益处,尤其是对败血症和白蛋白水平低的患者。进一步的分析探讨了剂量-反应关系,并确定了可从补充白蛋白中获益的潜在人群:结论:白蛋白在预测重症患者死亡率方面发挥着重要作用。此外,补充白蛋白可提高生存率,尤其是在资源有限的情况下。未来的研究应通过临床试验完善方案,以优化重症患者的存活率。
{"title":"The role of serum albumin in critical illness, predicting poor outcomes, and exploring the therapeutic potential of albumin supplementation.","authors":"Razan Rabi, Reem M Alsaid, Abdelrahman N Matar, Yusuf Dawabsheh, Dina Abu Gaber","doi":"10.1177/00368504241274023","DOIUrl":"10.1177/00368504241274023","url":null,"abstract":"<p><strong>Objective: </strong>Serum albumin (ALB) plays a vital role in maintaining oncotic pressure and contributing to hemodynamic stability, with low levels associated with adverse outcomes in critically ill patients. This study aimed to assess the association between serum ALB concentrations and poor outcomes and the possible benefits of ALB supplementation.</p><p><strong>Methods: </strong>A retrospective study involving 300 intensive care unit (ICU) patients. Albumin levels were recorded upon admission and throughout the stay, and patients were categorized based on a cutoff of 2.49 g/dl. The associations between low ALB levels and mortality were assessed using regression analysis. Additionally, it investigated the association of albumin supplementation with patient outcomes and mortality in specific patient populations.</p><p><strong>Results: </strong>The mean age was 54.9 years, with 68% having sepsis. Patients with low baseline ALB concentrations exhibited higher overall mortality (71% vs. 52%) and 28-day mortality (50% vs. 39%). Adjusted analyses confirmed associations with mortality. Albumin supplementation was administered to 53% of the patients. Its use demonstrated potential benefits, particularly in reducing mortality, when given to specific groups, such as sepsis and hypoalbuminemia patients.</p><p><strong>Discussion: </strong>The study confirms that low serum albumin levels are strongly associated with higher mortality rates in ICU patients. Albumin supplementation showed potential benefits, particularly in patients with sepsis and low albumin levels. Further analyses explored the dosage-response relationship and identified potential groups that would benefit from albumin supplementation.</p><p><strong>Conclusion: </strong>Albumin can play a major role in predicting mortality in critically ill patients. Moreover, ALB supplementation may improve survival, especially in resource-limited settings. Future research should refine protocols through clinical trials for optimal survival in critically ill patients.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11363227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on ride comfort optimization of the vehicle considering the subframe. 考虑到副车架,对车辆的乘坐舒适性进行优化研究。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241260272
Jin Gao, Mingyang Du

When the vehicle is in motion, the elastic deformation of the flexible subframe significantly influences ride comfort. Therefore, it is crucial to investigate the impact of flexible subframes on vehicle ride comfort. In order to enhance the reliability and optimization efficiency of our research, this paper incorporates the concept of elastic deformation in the flexible subframe into the investigation of vehicle ride comfort, and proposes a multi-objective optimization approach to enhance the overall vehicle ride comfort. The vibration mathematical model elucidates how flexible subframes affect vehicle ride comfort and establishes a rigid-flexible coupling model for a specific vehicle with a flexible subframe to analyze the impact of its elastic deformation on vehicle ride comfort through simulation experiments. Subsequently, a radial basis function approximation model is established, and the multi-objective particle swarm optimization and non-dominated sorting genetic algorithm II algorithms are employed to conduct multi-objective optimization of the stiffness of the subframe bushing with the aim of enhancing vehicle ride comfort. The findings indicate that the flexible subframe has a significant impact on vehicle ride comfort. Specifically, on bump roads, peak values of vertical and longitudinal seat accelerations decrease while lateral seat acceleration increases. On random roads, peak values of longitudinal and lateral seat accelerations increase while vertical acceleration decreases. Furthermore, the stiffness of the subframe bushing optimized by the non-dominated sorting genetic algorithm II algorithm further enhances vehicle ride comfort and aligns more closely with the optimization requirements in this study.

当车辆行驶时,柔性副车架的弹性变形对乘坐舒适性有很大影响。因此,研究柔性副车架对车辆行驶舒适性的影响至关重要。为了提高研究的可靠性和优化效率,本文将柔性副车架弹性变形的概念融入到车辆乘坐舒适性的研究中,并提出了一种多目标优化方法,以提高整车的乘坐舒适性。振动数学模型阐明了柔性副车架对车辆乘坐舒适性的影响,并针对特定车辆的柔性副车架建立了刚柔耦合模型,通过仿真实验分析其弹性变形对车辆乘坐舒适性的影响。随后,建立了径向基函数近似模型,并采用多目标粒子群优化和非支配排序遗传算法 II 算法,对副车架衬套的刚度进行多目标优化,以期提高车辆的乘坐舒适性。研究结果表明,柔性副车架对车辆行驶舒适性有显著影响。具体来说,在颠簸路面上,纵向和纵向座椅加速度峰值降低,而横向座椅加速度增加。在随机道路上,纵向和横向座椅加速度峰值增加,而垂直加速度减少。此外,通过非支配排序遗传算法 II 算法优化的副车架衬套刚度进一步提高了车辆的乘坐舒适性,更符合本研究的优化要求。
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引用次数: 0
Predictive analytics for traffic flow optimization in urban logistics: A transformer-based time series approach. 城市物流交通流优化预测分析:基于变压器的时间序列方法
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241265196
Qingling Tao

In this study, we focus on the analysis and prediction of urban logistics traffic flow, a field that is gaining increasing attention due to the acceleration of global urbanization and heightened environmental awareness. Existing forecasting methods face challenges in processing large and complex datasets, particularly when extracting and analyzing valid information from these data, often hindered by noise and outliers. In this context, time series analysis, as a key technique for predicting future trends, becomes crucial for supporting real-time traffic management and long-term traffic planning. To this end, we propose a composite network model that integrates gated recurrent unit (GRU), autoregressive integrated moving average (ARIMA), and temporal fusion transformer (TFT), namely the GRU-ARIMA-TFT network model, to enhance prediction accuracy and efficiency. Through the analysis of experimental results on different datasets, we demonstrate the significant advantages of this model in improving prediction accuracy and understanding complex traffic patterns. This research not only theoretically expands the boundaries of urban logistics traffic flow prediction but also holds substantial practical significance in real-world applications, especially in optimizing urban traffic planning and logistics distribution strategies during peak periods and under complex traffic conditions. Our study provides a robust tool for addressing real-world issues in the urban logistics domain and offers new perspectives and methodologies for future urban traffic management and logistics system planning.

在本研究中,我们将重点放在城市物流交通流的分析和预测上,由于全球城市化进程的加速和环境意识的提高,这一领域正日益受到关注。现有的预测方法在处理大型复杂数据集时面临挑战,特别是从这些数据中提取和分析有效信息时,往往会受到噪声和异常值的阻碍。在这种情况下,时间序列分析作为预测未来趋势的关键技术,对于支持实时交通管理和长期交通规划至关重要。为此,我们提出了一种融合了门控递归单元(GRU)、自回归整合移动平均(ARIMA)和时序融合变换器(TFT)的复合网络模型,即 GRU-ARIMA-TFT 网络模型,以提高预测精度和效率。通过对不同数据集的实验结果分析,我们证明了该模型在提高预测精度和理解复杂交通模式方面的显著优势。这项研究不仅从理论上拓展了城市物流交通流预测的范围,而且在实际应用中,尤其是在高峰期和复杂交通条件下优化城市交通规划和物流配送策略方面,具有重要的现实意义。我们的研究为解决城市物流领域的现实问题提供了一个强大的工具,并为未来的城市交通管理和物流系统规划提供了新的视角和方法。
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引用次数: 0
Enhancing 3D-printed denture base resins: A review of material innovations. 增强 3D 打印义齿基底树脂:材料创新综述。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241263484
Hadeel Fikrat Majeed, Thekra Ismael Hamad, Latifa R Bairam

The limited physical and mechanical properties of polymethyl methacrylate (PMMA), the current gold standard, necessitates exploring improved denture base materials. While three-dimensional (3D) printing offers accuracy, efficiency, and patient comfort advantages, achieving superior mechanics in 3D-printed denture resins remains challenging despite good biocompatibility and esthetics. This review investigates the potential of innovative materials to address the limitations of 3D-printed denture base materials. Thus, this article is organized to provide a comprehensive overview of recent efforts to enhance 3D-printed denture base materials, highlighting advancements. It critically examines the impact of incorporating various nanoparticles (zirconia, titania, etc.) on these materials' physical and mechanical properties. Additionally, it delves into recent strategies for nanofiller surface treatment and biocompatibility evaluation and explores potential future directions for polymeric composites in denture applications. The review finds that adding nanoparticles significantly improves performance compared to unmodified resins, and properties can be extensively enhanced through specific modifications, particularly silanized nanoparticles. Optimizing 3D-printed denture acrylics requires a multifaceted approach, with future research prioritizing novel nanomaterials and surface modification techniques for a novel generation of superior performance, esthetically pleasing, and long-lasting dentures.

聚甲基丙烯酸甲酯(PMMA)是目前的黄金标准,但其物理和机械性能有限,因此有必要探索改良的义齿基托材料。虽然三维(3D)打印具有精度高、效率高和患者舒适度高的优点,但尽管具有良好的生物相容性和美观性,要在 3D打印义齿树脂中实现卓越的机械性能仍然是一项挑战。本综述探讨了创新材料在解决三维打印义齿基底材料局限性方面的潜力。因此,本文旨在全面综述近期在增强三维打印义齿基底材料方面所做的努力,重点介绍取得的进展。文章认真研究了加入各种纳米粒子(氧化锆、二氧化钛等)对这些材料的物理和机械性能的影响。此外,它还深入探讨了纳米填料表面处理和生物相容性评估的最新策略,并探讨了聚合物复合材料在义齿应用中的潜在未来发展方向。综述发现,与未经改性的树脂相比,添加纳米颗粒可显著提高性能,而且通过特定改性,特别是硅烷化纳米颗粒,可广泛增强性能。优化三维打印义齿丙烯酸树脂需要多方面的方法,未来的研究将优先考虑新型纳米材料和表面改性技术,以生产出性能优越、美观耐用的新一代义齿。
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引用次数: 0
Coordinated changes in sensorimotor integration underlie behavioral change through evolution and plasticity: A case study in weakly electric mormyrid fish. 通过进化和可塑性,感觉运动整合的协调变化是行为变化的基础:弱电鲂鱼的案例研究。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241269438
Matasaburo Fukutomi, Bruce A Carlson
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引用次数: 0
Endovascular Perclose ProGlide complication puncture site, treated successful by cutting balloon dilatation: A case report and literature review. 血管内 Perclose ProGlide 穿刺部位并发症,通过切割球囊扩张成功治愈:病例报告和文献综述。
IF 2.6 4区 综合性期刊 Q2 MULTIDISCIPLINARY SCIENCES Pub Date : 2024-07-01 DOI: 10.1177/00368504241278481
Yulong Huang, Xinsheng Xie, Lixin Wang

Perclose ProGlide were created as preferred for puncture site closure of femoral artery. Femoral artery occlusion is one of the serious device-related complications. This report presents a continuous endovascular technique combined with peripheral cutting balloon (PCB) treatment for a case of a 32s woman diagnosed with lower extremity ischaemia caused by right superficial femoral artery (SFA) occlusion following the use of the Perclose ProGlide system in minimally invasive cardiac surgery. During the primary operation, limb ischaemia symptoms were relieved with vessel perfusion and reconstruction after regular balloon dilatation. A secondary operation was conducted 6 weeks later, and the obstructive lesions were recanalised without residual stenosis after PCB dilatation. No vessel-related adverse events such as dissection, rupture or distal embolisation occurred during the perioperative period. The patient recovered uneventfully after the operation, with complete alleviation of symptoms. Follow-up computed tomography angiography 3 month post-operatively revealed an undeformed shape and excellent patency of the right SFA.

Perclose ProGlide 是用于股动脉穿刺部位闭合的首选产品。股动脉闭塞是与器械相关的严重并发症之一。本报告介绍了在微创心脏手术中使用 Perclose ProGlide 系统后,结合外周切割球囊(PCB)治疗的连续血管内技术,该病例是一名 32 岁女性,因右股浅动脉(SFA)闭塞而被诊断为下肢缺血。在初次手术中,通过常规球囊扩张后的血管灌注和重建,肢体缺血症状得到缓解。6 周后进行了二次手术,阻塞性病变在 PCB 扩张后被重新疏通,没有残余狭窄。围手术期未发生血管相关不良事件,如夹层、破裂或远端栓塞。术后患者恢复顺利,症状完全缓解。术后 3 个月的随访计算机断层扫描血管造影显示,右侧 SFA 的形状未变形,通畅性良好。
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引用次数: 0
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Science Progress
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