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Low-velocity impact response of hybrid core sandwich panels with spring and strut cores filled with resin, silicone, and foam 混合芯材夹芯板的低速冲击响应,其弹簧和支柱芯材中填充了树脂、硅酮和泡沫塑料
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-22 DOI: 10.1186/s40712-024-00158-8
Assil Charkaoui, Noha M. Hassan, Zied Bahroun, Mahmoud Ibrahim

Advancements in the load-bearing capacity of composite panels open doors to high-performance applications. The integration of additive manufacturing allows for the creation of intricate core designs effortlessly. Hybrid cores, combining structural elements with infill materials, play a crucial role in enhancing panel impact resistance while maintaining its low weight. This study compares sandwich panels incorporating spring and octet strut structural elements infused with different materials—silicon, foam, and epoxy resin—evaluating their energy absorption capabilities. Additive manufacturing is employed to produce these panels with structural elements then subsequently filled with infills. The drop tower test is utilized to experimentally assess panel behavior under low-velocity impact. Design of experiments and statistical analysis are used to examine the influence of core height, impact height, core geometry, and filling type on the damaged area and impactor penetration. Results showed that the strut-based structure performed better than other structures in preventing penetration, with a damaged area reduction from 501.45 to 301.58 m2 compared to the spring core. The addition of foam or silicon reduced the impact damage to the front and the back sheets, with silicon infills proving to be the most effective, reducing penetration by reducing penetration by about 60%. The depth of impact was measured, with results indicating that the truss core displayed the smallest specific depth of penetration. A decision tree model predicted that a sandwich panel with a spring core would have a 100% chance of perforation while a filled core showed a significantly reduced penetration risk.

复合板承重能力的提高为高性能应用打开了大门。增材制造技术的集成可以毫不费力地创造出复杂的芯材设计。混合芯材将结构元素与填充材料相结合,在增强板材抗冲击能力的同时保持低重量方面发挥着至关重要的作用。本研究比较了采用不同材料(硅、泡沫和环氧树脂)填充弹簧和八字形支柱结构件的夹芯板,评估了它们的能量吸收能力。该研究采用快速成型技术生产这些带有结构元件的面板,然后再填充填充物。利用落塔试验对面板在低速冲击下的行为进行实验评估。实验设计和统计分析用于研究芯材高度、撞击高度、芯材几何形状和填充类型对受损面积和撞击器穿透力的影响。结果表明,基于支柱的结构在防止穿透方面的表现优于其他结构,与弹簧芯材相比,受损面积从 501.45 平方米减少到 301.58 平方米。添加泡沫或硅减少了对前板和后板的撞击破坏,其中硅填充被证明是最有效的,可减少约 60% 的穿透力。对冲击深度进行了测量,结果表明桁架芯材的穿透深度最小。根据决策树模型预测,带有弹簧芯材的夹芯板穿孔几率为 100%,而填充芯材的穿孔风险则大大降低。
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引用次数: 0
Doped holes and/or electrons induced superconductivity domes explained with the free volume concept 用自由体积概念解释掺杂空穴和/或电子诱导的超导穹顶
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-21 DOI: 10.1186/s40712-024-00159-7
Tian Hao

The conductivity equation developed in our previous work without any restrictions to specific materials is employed to explore how superconductivity transition temperature (T_{c}) changes with the doped hole or electron concentrations based on the free volume concept. The predicted relationship is used to fit experimental data available in the literature and a good agreement with observations is achieved. Our findings may provide an alternative explanation for doping-induced domes and/or double domes with a-dip phenomena observed among many superconductors.

基于自由体积概念,我们采用了之前工作中开发的、不受特定材料限制的传导方程来探索超导转变温度(T_{c})是如何随掺杂空穴或电子浓度的变化而变化的。所预测的关系被用来拟合文献中的实验数据,结果与观测数据十分吻合。我们的发现可以为在许多超导体中观察到的掺杂诱导圆顶和/或双圆顶a-dip现象提供另一种解释。
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引用次数: 0
Enhancing Ni–Ti shape memory alloy diffusion bonding with Ti/Ni reactive multilayer foils 利用钛/镍反应多层箔增强镍-钛形状记忆合金的扩散接合
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-13 DOI: 10.1186/s40712-024-00162-y
Mohammad Mokhles, Seyed Mojtaba Zebarjad, Habib Danesh-Manesh, Tushar R. Dandekar

This study investigates the utilization of Ti/Ni reactive multilayer foils as an energy source for facilitating the joining of Ni–Ti shape memory alloys through diffusion bonding. Multilayered samples were prepared using a 10-cycle accumulative roll bonding (ARB) process to be used for the bonding process. Diffusion bonding employing reactive multilayers was conducted over a temperature range of 600 °C to 900 °C, at 5 MPa pressure, with a 1-h hold time. Additionally, a comparison was made with a diffusion-bonded Nitinol sample at 900 °C without a reactive multilayer. Materials characterization and testing involved scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), shear strength testing, and differential scanning calorimetry (DSC), which were conducted on the bonded samples. The findings underscored the advantages of using reactive multilayers for diffusion bonding. These benefits included the formation of TiNi and the induction of a shape memory effect in the joint region, alongside a 1.5 times shear strength compared to identical diffusion bonding conditions without reactive multilayers. Moreover, employing reactive multilayers in the diffusion bonding of Nitinol holds promise for significantly reducing the energy needed to achieve robust and seamless bonded boundaries in the joining area.

本研究探讨了如何利用钛/镍反应多层箔作为能源,通过扩散键合促进镍钛形状记忆合金的连接。使用 10 周期累积辊粘合 (ARB) 工艺制备了多层样品,用于粘合工艺。在 5 兆帕压力和 1 小时保持时间下,在 600 °C 至 900 °C 的温度范围内进行了采用反应多层膜的扩散接合。此外,还与 900 °C 时未使用反应多层膜的扩散键合镍钛诺样品进行了比较。材料表征和测试包括扫描电子显微镜 (SEM)、能量色散光谱 (EDS)、剪切强度测试和差示扫描量热法 (DSC)。研究结果凸显了使用反应多层膜进行扩散粘合的优势。这些优点包括在接合区域形成 TiNi 和诱导形状记忆效应,同时与没有反应多层膜的相同扩散粘合条件相比,剪切强度提高了 1.5 倍。此外,在镍钛诺的扩散接合中采用反应多层膜有望显著降低接合区域实现稳固无缝接合边界所需的能量。
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引用次数: 0
Self-assembled rectorite films with remarkable mechanical performance: preparation, structural characterization, and properties 具有卓越机械性能的自组装雷克托石薄膜:制备、结构表征和性能
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-13 DOI: 10.1186/s40712-024-00161-z
Maria T. Atanasova, Walter W. Focke, Theodor Loots

Cohesive flexible rectorite clay films with good mechanical performance were prepared by a simple casting method through the self-assembly of exfoliated natural clay from aqueous dispersions. The multi-layered microstructure of the films consisted of continuous layers of aligned clay platelets parallel to the casting surface. Layers overlap randomly in the lateral direction (plane) and join vertically in an irregular manner by edge-to-face cross-linkages (bridging) to form coherent multi-layered nanostructured films with platelet-void microstructure. The films with the highest mechanical properties had thicknesses below 30 µm. Overall films from rectorite clay with monovalent interlayer content exhibited a higher experimental tensile strength ranging up to 44 MPa and Young’s modulus up to 56 GPa. The corresponding experimental values for films with divalent interlayer cations were 23 MPa for strength and 25 GPa for modulus. The highest experimental values for strength and modulus for neat Na–Ca–rectorite films were 25 MPa and 50 GPa respectively. These two mechanical property values of the best rectorite-based clay films compare favorably with values featured by polymer films typically used for packaging applications.

通过从水分散液中自组装剥离的天然粘土,采用简单的浇铸方法制备出了具有良好机械性能的内聚柔性雷克托石粘土薄膜。薄膜的多层微观结构由平行于浇铸表面的连续排列的粘土板层组成。各层在横向(平面)随机重叠,并通过边缘到表面的交联(桥接)以不规则的方式垂直连接,形成具有血小板空泡微观结构的连贯多层纳米结构薄膜。机械性能最高的薄膜厚度低于 30 微米。具有单价层间含量的雷克托石粘土薄膜总体显示出较高的实验拉伸强度,最高可达 44 兆帕,杨氏模量最高可达 56 千兆帕。含有二价层间阳离子的薄膜的相应实验值为:强度 23 兆帕,模量 25 千兆帕。纯 Na-Ca 雷克托石薄膜的最高强度和模量实验值分别为 25 兆帕和 50 千兆帕。基于雷克托石的最佳粘土薄膜的这两个机械性能值与通常用于包装的聚合物薄膜的机械性能值相比毫不逊色。
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引用次数: 0
Sustainable polymer reclamation: recycling poly(ethylene terephthalate) glycol (PETG) for 3D printing applications 可持续聚合物再生:回收聚对苯二甲酸乙二醇(PETG)用于 3D 打印应用
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-12 DOI: 10.1186/s40712-024-00163-x
João Daniel Seno Flores, Thiago de Assis Augusto, Daniel Aparecido Lopes Vieira Cunha, Cesar Augusto Gonçalves Beatrice, Eduardo Henrique Backes, Lidiane Cristina Costa

Due to their versatile properties and wide-ranging applications across various industries, including manufacturing, polymers are indispensable for today’s society. However, polymer-based products significantly impact the environment since many are single-used plastics and require a long time to degrade naturally. A method to attenuate end-of-life polymers’ ill effects is recycling them to bring them again into the production cycle, from grave to cradle. This investigation involves recycling PETG sheets used in face shield production during the COVID-19 outbreak to fabricate 3D printing filaments for FFF. We assessed poly(ethylene terephthalate) glycol (PETG) processability to up to five recycling cycles and obtained filaments with properties adequate for 3D printing. Rheological, thermal, morphological, and mechanical characterization were analyzed to verify the effect of the number of processing cycles on the properties of the polymer. The recycling cycles originated a decrease in viscosity and elasticity, and the gain in molecular mobility resulted, relatively, in solids with a higher degree of crystallinity and prints with more elliptical depositions. The mechanical properties of printed parts fabricated of recycled material were comparable to those from commercial filament, especially after three extrusion cycles. Both extrusion and additive manufacturing processes successfully recycle material into filaments and printed parts, indicating that the proposed methodology is a promising alternative to bring value back to polymers from solid waste.

聚合物具有多种特性,在包括制造业在内的各行各业都有广泛应用,是当今社会不可或缺的物质。然而,由于许多聚合物产品都是一次性塑料,需要很长时间才能自然降解,因此对环境造成了严重影响。减少报废聚合物不良影响的一种方法是对其进行回收利用,使其重新进入从坟墓到摇篮的生产循环。这项调查涉及回收 COVID-19 疫情爆发期间用于面罩生产的 PETG 片材,以制造用于 FFF 的 3D 打印长丝。我们评估了聚对苯二甲酸乙二酯(PETG)在长达五个回收周期内的可加工性,并获得了具有适合 3D 打印的特性的长丝。我们对流变学、热学、形态学和机械特性进行了分析,以验证加工循环次数对聚合物特性的影响。循环次数导致粘度和弹性下降,而分子流动性的增加则使固体结晶度更高,打印件的椭圆形沉积更多。用回收材料制造的打印部件的机械性能与商用长丝不相上下,尤其是在经过三个挤压周期后。挤压和增材制造工艺都能成功地将材料回收利用为长丝和印刷部件,这表明所提出的方法是一种很有前途的替代方法,能从固体废弃物中重新获得聚合物的价值。
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引用次数: 0
Experimental study of characterization and optimization of shape memory alloy sheet for enhanced mechanical actuation performance for microelectromechanical systems (MEMS) 表征和优化形状记忆合金薄片以提高微机电系统 (MEMS) 机械致动性能的实验研究
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-11 DOI: 10.1186/s40712-024-00160-0
Suraj, Arun Kumar

In this paper, a shape memory alloy (SMA), NiTiNOL, zigzag sheet is used and experimental method is developed using programmable power supply, laser displacement sensor, and K-type thermocouple to investigate actuation and thermo-mechanical behavior of trained SMA zigzag sheet under three different weights, 2.5 N, 3.5 N, and 4.5 N, along with three distinct voltage levels 2.0 V, 3.0 V, and 4.0 V and hysteresis curves are comprehensively examined to get optimum value of load and voltage to achieve better life cycle and actuation as per the requirement of the design. The displacement and temperature data of the zigzag sheet is recorded for every 200 ms for the entire operating life, utilizing heating and cooling processes, of the zigzag sheet and the value of constant displacement for each cycle is optimized which can be used for the development of microelectromechanical systems (MEMS).

本文使用形状记忆合金 (SMA)、NiTiNOL 和人字形薄片,并开发了使用可编程电源、激光位移传感器和 K 型热电偶的实验方法,以研究训练有素的 SMA 人字形薄片在 2.5 N、3.5 N 和 4.5 N 三种不同重量以及 2.0 V、3.0 V 和 4.0 V 三种不同电压水平下的致动和热机械行为。在 2.5 N、3.5 N 和 4.5 N 三种不同重量以及 2.0 V、3.0 V 和 4.0 V 三种不同电压水平下的致动和热机械行为,并对滞后曲线进行了全面检查,以获得最佳负载和电压值,从而根据设计要求实现更好的使用寿命和致动。利用加热和冷却过程,记录了人字形薄片在整个工作寿命期间每 200 毫秒的位移和温度数据,并优化了每个周期的恒定位移值,该值可用于开发微机电系统(MEMS)。
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引用次数: 0
Advancements in bandgap engineering: bromide-doped cesium lead perovskite thin films 带隙工程的进展:溴掺杂铯铅过氧化物薄膜
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-05 DOI: 10.1186/s40712-024-00156-w
Khawla Fradi, Amal Bouich, Yousaf Hameed Khattak, Faisal Baig, Bechir Slimi, Bernabé Marí Soucase, Radhouane Chtourou

Perovskite materials have emerged as promising candidates for next-generation photovoltaic devices due to their unique optoelectronic properties. In this study, we investigate the incorporation of bromine into cesium lead mixed iodide and bromide perovskites (CsPbI3(1-x)Br3x) to enhance their performance. By depositing films with varying bromine concentrations (x = 0, 0.25, 0.5, 0.75), we employ a combination of structural and optical characterization techniques, including X-ray diffraction (XRD), scanning electron microscopy (SEM), UV–visible spectroscopy, and photoluminescence. Our analysis reveals that introducing bromine leads to structural modifications, influencing the perovskite films’ optical properties and energy gap. Specifically, we observe semiconductor behavior with a tunable energy gap controlled by the intercalation of bromine atoms into the CsPbI3 lattice. Furthermore, heat treatment induces phase transitions in the perovskite films, affecting their optical responses and crystalline quality. SCAPS-1D simulations confirm the improved stability and efficiency of bromine-doped CsPbI3 films compared to undoped counterparts. Our findings demonstrate that bromine incorporation facilitates the formation of highly crystalline perovskite films with reduced trap defects and enhanced carrier transport properties. These results underscore the potential of bromine-doped CsPbI3 perovskites as promising materials for high-performance photovoltaic applications, paving the way for further optimization and device integration.

透镜材料因其独特的光电特性,已成为下一代光伏设备的理想候选材料。在本研究中,我们探讨了将溴掺入铯铅混合碘化物和溴化物包晶(CsPbI3(1-x)Br3x)以提高其性能的问题。通过沉积不同溴浓度(x = 0、0.25、0.5、0.75)的薄膜,我们综合运用了结构和光学表征技术,包括 X 射线衍射 (XRD)、扫描电子显微镜 (SEM)、紫外可见光谱和光致发光。我们的分析表明,溴的引入会导致结构的改变,从而影响包晶体薄膜的光学特性和能隙。具体来说,我们观察到半导体行为,其可调能隙受 CsPbI3 晶格中的溴原子插层控制。此外,热处理会诱导包晶体薄膜发生相变,从而影响其光学响应和结晶质量。SCAPS-1D 模拟证实,与未掺杂的 CsPbI3 薄膜相比,掺溴 CsPbI3 薄膜的稳定性和效率都有所提高。我们的研究结果表明,溴的掺入有助于形成高结晶度的包晶体薄膜,减少阱缺陷,提高载流子传输性能。这些结果凸显了溴掺杂 CsPbI3 包晶石作为高性能光伏应用材料的潜力,为进一步优化和器件集成铺平了道路。
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引用次数: 0
Sustainable machining of AISI4140 steel: a Taguchi-ANN perspective on eco-friendly metal cutting parameters AISI4140 钢的可持续加工:从 Taguchi-ANN 角度看生态友好型金属切削参数
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-08-02 DOI: 10.1186/s40712-024-00154-y
Pankaj Krishnath Jadhav, R. S. N. Sahai

This work explores environmentally conscious machining practices for AISI4140 steel through Taguchi analysis. The study employs a design of experiments (DOE) approach, focusing on cutting speed, depth of cut, and coolant type as parameters. Taguchi’s L9 orthogonal array facilitates systematic experimentation, and the results are analyzed using MINITAB 17 software. Signal-to-noise ratios (SNR) are utilized to establish optimum operating conditions, evaluate individual parameter influences, and create linear regression models. The experiments reveal neem oil with graphene coolant as an eco-friendly solution, addressing health and environmental concerns. Main effects plots visually represent the impact of parameters on machining quality. Additionally, regression and artificial neural network (ANN) models are compared for surface roughness prediction, with ANN showing superior performance. The findings advocate for optimized cutting conditions, emphasizing material conservation, enhanced productivity, and eco-friendly practices in AISI4140 steel machining. This research contributes valuable insights for industries seeking sustainable machining solutions.

本研究通过田口分析法探讨了 AISI4140 钢的环保型加工方法。研究采用了实验设计(DOE)方法,重点关注切削速度、切削深度和冷却液类型等参数。田口 L9 正交阵列有助于进行系统实验,实验结果使用 MINITAB 17 软件进行分析。利用信噪比(SNR)确定最佳操作条件,评估各个参数的影响,并建立线性回归模型。实验表明,楝树油与石墨烯冷却剂是一种生态友好型解决方案,可解决健康和环境问题。主效应图直观地显示了参数对加工质量的影响。此外,还比较了回归模型和人工神经网络(ANN)模型对表面粗糙度的预测,其中人工神经网络显示出更优越的性能。研究结果提倡在 AISI4140 钢加工中优化切削条件,强调节约材料、提高生产率和环保实践。这项研究为寻求可持续加工解决方案的行业提供了宝贵的见解。
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引用次数: 0
Development of an opto-electrochemical sensor for the detection of malathion using manganese metal–organic framework (Mn-MOF) 利用锰金属有机框架(Mn-MOF)开发用于检测马拉硫磷的光电化学传感器
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-07-29 DOI: 10.1186/s40712-024-00157-9
Lakshya Sankhla, Himmat Singh Kushwaha

This paper presents a new method for detecting malathion pesticides using a modified screen-printed electrode (SPE) with a fluorescence quenching technique. The manganese-based MOF was synthesized using the solvothermal method. The synthesized MOFs were characterized by transmission electron microscopy (TEM), x-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and Raman spectroscopy. The material’s electrocatalytic properties were assessed via electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). Within the concentration range of 0.89 µM to 5.95 µM, the material’s response to malathion was analyzed with square wave voltammetry (SWV), giving rise to a detection limit of 39.097 nM. Fluorescence quenching studies have been carried out between 0.039 and 0.56 µM, with a lower detection limit of 62.03 nM. A sensor with good anti-interference properties was tested for selectivity and practicability in detecting malathion in real samples, proving its potential use in this area.

本文介绍了一种利用荧光淬灭技术的改良丝网印刷电极(SPE)检测马拉硫磷农药的新方法。本文采用溶热法合成了锰基 MOF。透射电子显微镜(TEM)、X 射线衍射(XRD)、傅立叶变换红外光谱(FT-IR)和拉曼光谱对合成的 MOFs 进行了表征。该材料的电催化特性通过电化学阻抗光谱法(EIS)和循环伏安法(CV)进行了评估。在 0.89 µM 至 5.95 µM 的浓度范围内,用方波伏安法(SWV)分析了材料对马拉硫磷的反应,检测限为 39.097 nM。在 0.039 至 0.56 µM 之间进行了荧光淬灭研究,检测下限为 62.03 nM。对具有良好抗干扰性能的传感器进行了选择性和实用性测试,以检测真实样品中的马拉硫磷,从而证明其在这一领域的潜在用途。
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引用次数: 0
Concentration modulated microstructure and rheological properties of nanofibrous hydrogels derived from decellularized human amniotic membrane for 3D cell culture 用于三维细胞培养的脱细胞人羊膜纳米纤维水凝胶的浓度调节微结构和流变特性
IF 3.4 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2024-07-29 DOI: 10.1186/s40712-024-00153-z
Golara Kafili, Elnaz Tamjid, Hassan Niknejad, Abdolreza Simchi

Decellularized amnion (dAM)-derived hydrogels have been extensively exploited for versatile medical and therapeutical applications, particularly for soft tissue engineering of skin, vascular graft, and endometrium. In contrast to polyacrylamide-based hydrogels, which have been extensively employed as a 3D cell culture platform, the cell response of dAM hydrogel is yet to be understood. In this study, we have prepared hydrogels containing different concentrations of dAM and systematically investigated their microstructural features, gelation kinetics, and rheological properties. The results show that dAM hydrogels possess a network of fibers with an average diameter of 56 ± 5 nm at 1% dAM, which increases to 110 ± 14 nm at 3% dAM. The enhanced intermolecular crosslinking between the microfibrillar units increases the gelation rate in the growth phase of the self-assembly process. Moreover, increasing the concentration of dAM in the hydrogel formulation (from 1 to 3%w/v) enhances the dynamic mechanical moduli of the derived hydrogels by about two orders of magnitude (from 41.8 ± 2.5 to 896.2 ± 72.3 Pa). It is shown that the variation in the hydrogel stiffness significantly affects the morphology of dermal fibroblast cells cultured in the hydrogels. It is shown that the hydrogels containing up to 2%w/v dAM provide a suitable microenvironment for embedded fibroblast cells with spindle-like morphology. Nevertheless, at the higher concentration, an adverse effect on the proliferation and morphology of fibroblast cells is noticed due to stiffness-induced phenotype transformation of cells. Concentration-modulated properties of dAM hydrogels offer an in vitro platform to study cell-related responses, disease modeling, and drug studies.

Graphical abstract

脱细胞羊膜(dAM)衍生水凝胶已被广泛应用于多种医疗和治疗领域,特别是皮肤软组织工程、血管移植和子宫内膜。与已被广泛用作三维细胞培养平台的聚丙烯酰胺基水凝胶相比,dAM 水凝胶的细胞反应尚待了解。在这项研究中,我们制备了含有不同浓度 dAM 的水凝胶,并系统地研究了它们的微观结构特征、凝胶化动力学和流变特性。结果表明,dAM 水凝胶具有平均直径为 56 ± 5 nm(1% dAM)的纤维网,3% dAM 时纤维网的平均直径增加到 110 ± 14 nm。微纤维单元之间分子间交联的增强提高了自组装过程生长阶段的凝胶化率。此外,提高水凝胶配方中 dAM 的浓度(从 1% 到 3%w/v)可将衍生水凝胶的动态机械模量提高约两个数量级(从 41.8 ± 2.5 到 896.2 ± 72.3 Pa)。研究表明,水凝胶硬度的变化会显著影响在水凝胶中培养的真皮成纤维细胞的形态。结果表明,含高达 2%w/v dAM 的水凝胶可为具有纺锤形形态的嵌入成纤维细胞提供合适的微环境。然而,当浓度较高时,成纤维细胞的增殖和形态会受到不利影响,原因是僵硬会导致细胞表型的转变。dAM 水凝胶的浓度调节特性为研究细胞相关反应、疾病建模和药物研究提供了一个体外平台。
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引用次数: 0
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International Journal of Mechanical and Materials Engineering
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