Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286264
Zhenzhen Xu, L. Kong
Increasing research attentions have been paid to the bionic structures and functional materials in recent years. In order to gain the insights into functional micro/nano-structures and hence form the theoretical basis for design and fabrication of such micro/nano-structural surfaces, this paper conducts a preliminary research study on functional micro/nano structural surfaces. A short review is firstly undertaken for the existing functional micro/nano structures in bionics, and then an analytical model for the Nepenthes Alata's peristome surface is proposed, as an example, which is applicable for production by ultra-precision machining technology. In the short review, existing functional structural surfaces are classified into three categories: structural surfaces with anti-adhesive properties, environmental adaptability structural surfaces, and biological structures with other specific functions. Research work for the above three categories are reviewed: (a) The structural surface with anti-adhesive properties. Super-hydrophobic self-cleaning surface inspired by lotus effect, low friction surface inspired by shark skin, as examples, are introduced and explained. Such structural surfaces have wide and promising applications in the fields of transportation, self-cleaning materials, biomedicine and so on. This has gained intensive interest from research and industry; (b) Environmental adaptability structural surface. The formation mechanism and its application of biological colors with broad military application prospects are reviewed and introduced; (c) Biological structure with specific functions. The latest research progress of insect compound eyes, desert beetle back surface, spider silk, peristome surface of Nepenthes alata and other structures are reviewed in this part. After that, the mechanism of unidirectional liquid spreading without extra energy input on the peristome surface of Nepenthes alata was further investigated, and the structures are also designed to improve the functions based on the existing research which is on the structures of the Nepenthes with one of the typical structures having the function of directional transport without extra power supply. Furthermore, a bionic design model was proposed and the model parameters were analyzed and optimized to achieve better functional performance. Future study for functional micro/nano structural surfaces is also suggested in the end of the paper.
{"title":"A study of functional micro/nano structural surfaces in bionic applications","authors":"Zhenzhen Xu, L. Kong","doi":"10.1109/3M-NANO.2017.8286264","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286264","url":null,"abstract":"Increasing research attentions have been paid to the bionic structures and functional materials in recent years. In order to gain the insights into functional micro/nano-structures and hence form the theoretical basis for design and fabrication of such micro/nano-structural surfaces, this paper conducts a preliminary research study on functional micro/nano structural surfaces. A short review is firstly undertaken for the existing functional micro/nano structures in bionics, and then an analytical model for the Nepenthes Alata's peristome surface is proposed, as an example, which is applicable for production by ultra-precision machining technology. In the short review, existing functional structural surfaces are classified into three categories: structural surfaces with anti-adhesive properties, environmental adaptability structural surfaces, and biological structures with other specific functions. Research work for the above three categories are reviewed: (a) The structural surface with anti-adhesive properties. Super-hydrophobic self-cleaning surface inspired by lotus effect, low friction surface inspired by shark skin, as examples, are introduced and explained. Such structural surfaces have wide and promising applications in the fields of transportation, self-cleaning materials, biomedicine and so on. This has gained intensive interest from research and industry; (b) Environmental adaptability structural surface. The formation mechanism and its application of biological colors with broad military application prospects are reviewed and introduced; (c) Biological structure with specific functions. The latest research progress of insect compound eyes, desert beetle back surface, spider silk, peristome surface of Nepenthes alata and other structures are reviewed in this part. After that, the mechanism of unidirectional liquid spreading without extra energy input on the peristome surface of Nepenthes alata was further investigated, and the structures are also designed to improve the functions based on the existing research which is on the structures of the Nepenthes with one of the typical structures having the function of directional transport without extra power supply. Furthermore, a bionic design model was proposed and the model parameters were analyzed and optimized to achieve better functional performance. Future study for functional micro/nano structural surfaces is also suggested in the end of the paper.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"1 1","pages":"206-209"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86378327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286320
Sen Wu, Huitian Bai, Fan Jin
Precise placement of individual nano scale objects is an essential requirement of nanodevices fabrication. Although the recently developed nanomanipulation technology based on Atomic force microscope (AFM) has realized automatic movement of rigid nanoparticles, it was not applicable to nanowires due to the complicated behaviors of flexible one-dimensional material. To improve the efficiency of nanowires manipulation, this work proposes a highly automated manipulation method. The new method allows automatic sample identification and manipulating vectors generation. Image processing techniques such as edge detection, filling and skeleton extraction are performed to identify the nanowires from the AFM images. Once a target position is assigned for the selected nanowire, a series of parallel pushing vectors (PPVs) are generated according to the translation and rotation strategies, which are simulated and optimized using the finite element method. Then the PPVs are continuously executed to transfer the nanowire to the target and make it in a straight shape. For multiple nanowires manipulation, a graph theory method is proposed to sort the movements of the objects. Because no intermediate scanning is needed, the time consumption of complex manipulation is greatly reduced. Experiments are carried out to verify the efficiency of the new method. The translating-rotating combined manipulation of a single silver nanowire proves the high accuracy of the proposed strategies. The successful assembly of two patterns, which are respectively formed by 12 carbon nanofibers and 50 silver nanowires, implies the reliability of the manipulation. Since the present method doesn't require additional hardware, it can be easily integrated to common AFMs.
{"title":"Automated manipulation of flexible nanowires with an atomic force microscope","authors":"Sen Wu, Huitian Bai, Fan Jin","doi":"10.1109/3M-NANO.2017.8286320","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286320","url":null,"abstract":"Precise placement of individual nano scale objects is an essential requirement of nanodevices fabrication. Although the recently developed nanomanipulation technology based on Atomic force microscope (AFM) has realized automatic movement of rigid nanoparticles, it was not applicable to nanowires due to the complicated behaviors of flexible one-dimensional material. To improve the efficiency of nanowires manipulation, this work proposes a highly automated manipulation method. The new method allows automatic sample identification and manipulating vectors generation. Image processing techniques such as edge detection, filling and skeleton extraction are performed to identify the nanowires from the AFM images. Once a target position is assigned for the selected nanowire, a series of parallel pushing vectors (PPVs) are generated according to the translation and rotation strategies, which are simulated and optimized using the finite element method. Then the PPVs are continuously executed to transfer the nanowire to the target and make it in a straight shape. For multiple nanowires manipulation, a graph theory method is proposed to sort the movements of the objects. Because no intermediate scanning is needed, the time consumption of complex manipulation is greatly reduced. Experiments are carried out to verify the efficiency of the new method. The translating-rotating combined manipulation of a single silver nanowire proves the high accuracy of the proposed strategies. The successful assembly of two patterns, which are respectively formed by 12 carbon nanofibers and 50 silver nanowires, implies the reliability of the manipulation. Since the present method doesn't require additional hardware, it can be easily integrated to common AFMs.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"19 1","pages":"229-235"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81729433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286294
Qifan Zhu, Zhiying Liu, Yuegang Fu, Chun-Jie Hao
Based on assumption of the visual system characteristics of the unidirectional microvilli array, this paper simulated the bionic model. The unidirectional microvilli array is simulated and it is simplified as cylinders, which is composed of material with index of refraction of n2 periodically arranged and is surrounded by medium with index of refraction of n1. Then, the bionic structure is equivalent to numbers of binary grating layers with different periods and thicknesses. Based on the effective medium theory (EMT) and transfer matrix method, this paper analyzed the relation between the transmittance of s-and p-modes and wavelengths in visible spectrum (400nm-700nm) for this bionic model. The result shows that the bionic model can work as a polarizer in two different narrow spectral ranges, and in two orthogonal polarization direction and can achieve the function of narrow-band and polarization cut-off filtering. Changing the thicknesses of the binary grating layers, the spectrum band of two spectral ranges would be different.
{"title":"Narrow-band and polarization cut-offfiltering based on the bionic structure of unidirectional microvilli array","authors":"Qifan Zhu, Zhiying Liu, Yuegang Fu, Chun-Jie Hao","doi":"10.1109/3M-NANO.2017.8286294","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286294","url":null,"abstract":"Based on assumption of the visual system characteristics of the unidirectional microvilli array, this paper simulated the bionic model. The unidirectional microvilli array is simulated and it is simplified as cylinders, which is composed of material with index of refraction of n2 periodically arranged and is surrounded by medium with index of refraction of n1. Then, the bionic structure is equivalent to numbers of binary grating layers with different periods and thicknesses. Based on the effective medium theory (EMT) and transfer matrix method, this paper analyzed the relation between the transmittance of s-and p-modes and wavelengths in visible spectrum (400nm-700nm) for this bionic model. The result shows that the bionic model can work as a polarizer in two different narrow spectral ranges, and in two orthogonal polarization direction and can achieve the function of narrow-band and polarization cut-off filtering. Changing the thicknesses of the binary grating layers, the spectrum band of two spectral ranges would be different.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"99 1","pages":"199-205"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80671446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286266
Tianyao Shen, B. Shirinzadeh, Y. Zhong, Julian Smith
Single cell microinjection is widely used in biological sciences, especially in genetic engineering and cytopathology. To investigate mechanical responses of the adherent cell in microinjection, a general geometrical description of adherent cells in microinjection is proposed. Based on finite strain theory in isotropic hyperelasticity and minimal potential energy principle, a hyperelastic model of the adherent cell is developed. Factors affecting the interaction force and the stress distribution in the adherent cell penetration are revealed and analyzed. The force-deformation relationship obtained in the proposed model shows high similarity with classical Hertz model, while more detailed mechanical behaviours of the adherent cell in microinjection can be discovered from the proposed model.
{"title":"A hyperelastic model for mechanical responses of adherent cells in microinjection","authors":"Tianyao Shen, B. Shirinzadeh, Y. Zhong, Julian Smith","doi":"10.1109/3M-NANO.2017.8286266","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286266","url":null,"abstract":"Single cell microinjection is widely used in biological sciences, especially in genetic engineering and cytopathology. To investigate mechanical responses of the adherent cell in microinjection, a general geometrical description of adherent cells in microinjection is proposed. Based on finite strain theory in isotropic hyperelasticity and minimal potential energy principle, a hyperelastic model of the adherent cell is developed. Factors affecting the interaction force and the stress distribution in the adherent cell penetration are revealed and analyzed. The force-deformation relationship obtained in the proposed model shows high similarity with classical Hertz model, while more detailed mechanical behaviours of the adherent cell in microinjection can be discovered from the proposed model.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"69 1","pages":"289-294"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84929903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286276
Dalia Mahdy, Abdallah Mohamed, A. Klingner, Ashraf Tammam, A. Wahdan, M. Serry, I. Khalil
This work in vestigates the locomotion of helical robots in a low Reynolds number environment with two different rheological properties. We study the swimming characteristics of the robot during its transition from a Newtonian fluid to a viscoelastic environment. Our experimental results show that the helical robot causes shear thinning in gelatin with intermediate concentration. Therefore, its speed in gelatin is greater than that in silicone oil. The helical robot swims at maximum speed of 0.36 mm/s in silicone oil with viscosity of 5 Pa.s, and 0.22 mm/s, 0.71 mm/s, and 0.94 mm/s in gelatin with concentration of 2%, 3% and 4%, respectively, under the influence of two rotating dipole fields.
{"title":"Experimental characterization of helical propulsion in Newtonian and viscoelastic mediums","authors":"Dalia Mahdy, Abdallah Mohamed, A. Klingner, Ashraf Tammam, A. Wahdan, M. Serry, I. Khalil","doi":"10.1109/3M-NANO.2017.8286276","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286276","url":null,"abstract":"This work in vestigates the locomotion of helical robots in a low Reynolds number environment with two different rheological properties. We study the swimming characteristics of the robot during its transition from a Newtonian fluid to a viscoelastic environment. Our experimental results show that the helical robot causes shear thinning in gelatin with intermediate concentration. Therefore, its speed in gelatin is greater than that in silicone oil. The helical robot swims at maximum speed of 0.36 mm/s in silicone oil with viscosity of 5 Pa.s, and 0.22 mm/s, 0.71 mm/s, and 0.94 mm/s in gelatin with concentration of 2%, 3% and 4%, respectively, under the influence of two rotating dipole fields.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"46 1","pages":"311-314"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91475084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286309
Yanling Wan, Lining Xu, Jinkai Xu, Jing Li, Yonghua Wang
Aluminum alloy surface was machined by nanosecond laser equipment, and the effect of different processing parameters on the microstructure of aluminum alloy surface was studied. The surface microstructure was observed by scanning electron microscopy and confocal microscopy. Surface hydrophobicity was evaluated with deionized water. The experiment results show that, by controlling the machining parameters, the surface microstructure morphology can be designed and controlled, at the same time, the influence of processing parameters on microstructure depth and width are also determined.
{"title":"Fabrication of size-controlled microstructures of Al alloy surface based on nanosecond laser","authors":"Yanling Wan, Lining Xu, Jinkai Xu, Jing Li, Yonghua Wang","doi":"10.1109/3M-NANO.2017.8286309","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286309","url":null,"abstract":"Aluminum alloy surface was machined by nanosecond laser equipment, and the effect of different processing parameters on the microstructure of aluminum alloy surface was studied. The surface microstructure was observed by scanning electron microscopy and confocal microscopy. Surface hydrophobicity was evaluated with deionized water. The experiment results show that, by controlling the machining parameters, the surface microstructure morphology can be designed and controlled, at the same time, the influence of processing parameters on microstructure depth and width are also determined.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"29 1","pages":"161-164"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75772936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nanopores promise wide applications in biosensing, ion-sieve and supercapacitors, ect. However, when the pore diameter approaches nanoscale, ion dynamic properties would deviate from the continuum analysis. In this paper, we reported that ion mobility in a nanopore depended on the surface hydrophobicity of the nanopore material through molecular dynamics (MD) simulation methods. The surface hydrophobicity was regulated by changing the polarity of the Si-N bond and the Van der Waals coefficient. For the nonpolar bond case, the solid-liquid hydrophobic force left an area as expressway for ion and water transport. The ion velocity within 3 Â of the surface was even faster than that in the central diffusion layer. In contrast, for the polar bond case, the strong interaction between the surface charges and the counter ions resulted in the formation of the Stern layer where the velocity of ions as well as water molecules sharply deviated from pore center value. Consequently, the average Na+ velocity in the polar bond nanopore was at least 5 times slower than that in non-polar bond nanopore.
{"title":"Anomalous ion transport through hydrophilic and hydrophobic nanopores","authors":"Kun Li, Zhongwu Li, Kabin Lin, Chen Chen, Pinyao He, Jingjie Sha, Yunfei Chen","doi":"10.1109/3M-NANO.2017.8286269","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286269","url":null,"abstract":"Nanopores promise wide applications in biosensing, ion-sieve and supercapacitors, ect. However, when the pore diameter approaches nanoscale, ion dynamic properties would deviate from the continuum analysis. In this paper, we reported that ion mobility in a nanopore depended on the surface hydrophobicity of the nanopore material through molecular dynamics (MD) simulation methods. The surface hydrophobicity was regulated by changing the polarity of the Si-N bond and the Van der Waals coefficient. For the nonpolar bond case, the solid-liquid hydrophobic force left an area as expressway for ion and water transport. The ion velocity within 3 Â of the surface was even faster than that in the central diffusion layer. In contrast, for the polar bond case, the strong interaction between the surface charges and the counter ions resulted in the formation of the Stern layer where the velocity of ions as well as water molecules sharply deviated from pore center value. Consequently, the average Na+ velocity in the polar bond nanopore was at least 5 times slower than that in non-polar bond nanopore.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"63 1","pages":"151-155"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90252722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper, the milling experiments of the 7075 Aluminum alloy thin wall specimens are carried out. In the dry cutting under the experimental conditions, the hard alloy cutter the use of the 7075 Aluminum alloy milling can get better quality of the thin-walled specimens, machining, cutting and cutting edge burr and the source, the chip adhesion phenomenon, in the selection of cutting speed for variable conditions, with the increase of cutting speed, milling of thin-walled specimen deformation gradually becomes smaller the thin, the specimen surface residual stress gradually increase, in the selection of feed speed conditions within the range of variables, with the increase of feed speed, the 7075 Aluminum alloy milling of thin-walled specimens. The deformation degree increased, thin specimen surface residual stress decreases gradually, in the selection of cutting depth conditions the range of variables, with the increase of cutting depth, the 7075 Aluminum alloy test milling of thin-walled parts is the greater the degree of deformation, thin-walled specimen surface residual stress was gradually decreased, residual stress the hour gradually thin plate specimens deformation amount is small, the milling of thin-walled specimens after deformation is inevitable.
{"title":"Experimental study on cutting characteristics of thin walled structures with weak rigidity","authors":"Qimeng Liu, Jinkai Xu, Huadong Yu, Zhanjiang Yu, Yiquan Li, Yanling Wan, Xianghui Zhang, Zhongxu Lian","doi":"10.1109/3M-NANO.2017.8286327","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286327","url":null,"abstract":"In this paper, the milling experiments of the 7075 Aluminum alloy thin wall specimens are carried out. In the dry cutting under the experimental conditions, the hard alloy cutter the use of the 7075 Aluminum alloy milling can get better quality of the thin-walled specimens, machining, cutting and cutting edge burr and the source, the chip adhesion phenomenon, in the selection of cutting speed for variable conditions, with the increase of cutting speed, milling of thin-walled specimen deformation gradually becomes smaller the thin, the specimen surface residual stress gradually increase, in the selection of feed speed conditions within the range of variables, with the increase of feed speed, the 7075 Aluminum alloy milling of thin-walled specimens. The deformation degree increased, thin specimen surface residual stress decreases gradually, in the selection of cutting depth conditions the range of variables, with the increase of cutting depth, the 7075 Aluminum alloy test milling of thin-walled parts is the greater the degree of deformation, thin-walled specimen surface residual stress was gradually decreased, residual stress the hour gradually thin plate specimens deformation amount is small, the milling of thin-walled specimens after deformation is inevitable.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"38 1","pages":"95-99"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91546456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286318
Wenxue Wang, Yuechao Wang, B. Liu, Lianqing Liu, Bo Wang
Organisms are composed by cells, and the cells can also reflect the physiology of creatures. The composition of a single cell and its cytoskeletal structure can be reflected by the mechanical properties of the cell. The cellular mechanical properties are correlated to the biological functions of the cell and its physiological activities. Therefore, establishing the mathematical model for the mechanical properties of single cells could provide the foundation for analyzing and regulating the physiological state of cells. In our previous work, we established a dynamical mathematical model with the viscose and elastic properties of single cells as the system parameters of the cellular system. The mathematical model can characterize the stressrelaxation phenomenon of a single cell, which is caused by an atomic force microscope (AFM). However, in this model, the effect of the loading rate of the AFM cantilever was neglected and all the stress-relaxation curves needed to be measured at a constant loading rate, in case that different loading rates would cause errors in the stress-relaxation curves. In this study, we discussed the effect of the loading rate on the measurement of cellular viscoelasticity properties with AFM. We clearly illustrated that the cellular stress-relaxation curves won't be effected by the loading rate of AFM when the loading rate is higher than a threshold. The stress-relaxation curves with the loading rate which is higher than the threshold can be used to extract viscoelasticity parameters more accurately.
{"title":"The effect of loading rate on the measurement of cellular viscoelasticity properties with atomic force microscopy","authors":"Wenxue Wang, Yuechao Wang, B. Liu, Lianqing Liu, Bo Wang","doi":"10.1109/3M-NANO.2017.8286318","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286318","url":null,"abstract":"Organisms are composed by cells, and the cells can also reflect the physiology of creatures. The composition of a single cell and its cytoskeletal structure can be reflected by the mechanical properties of the cell. The cellular mechanical properties are correlated to the biological functions of the cell and its physiological activities. Therefore, establishing the mathematical model for the mechanical properties of single cells could provide the foundation for analyzing and regulating the physiological state of cells. In our previous work, we established a dynamical mathematical model with the viscose and elastic properties of single cells as the system parameters of the cellular system. The mathematical model can characterize the stressrelaxation phenomenon of a single cell, which is caused by an atomic force microscope (AFM). However, in this model, the effect of the loading rate of the AFM cantilever was neglected and all the stress-relaxation curves needed to be measured at a constant loading rate, in case that different loading rates would cause errors in the stress-relaxation curves. In this study, we discussed the effect of the loading rate on the measurement of cellular viscoelasticity properties with AFM. We clearly illustrated that the cellular stress-relaxation curves won't be effected by the loading rate of AFM when the loading rate is higher than a threshold. The stress-relaxation curves with the loading rate which is higher than the threshold can be used to extract viscoelasticity parameters more accurately.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"13 1","pages":"246-249"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87683618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.1109/3M-NANO.2017.8286296
Xiaozhe Yuan, Yongchun Fang
Atomic force microscopy (AFM) is a powerful tool for measuring the topography and mechanical properties in nano-scale. The topography of the sample can be achieved by contact mode scanning, while the mechanical properties can be investigated with the help of force curve. However the force curve characterizes the mechanical properties of the sample at a certain point. In many cases, it is important to get the elasticity distribution of the entire surface, which means a huge amount of points need to be selected for measuring force curves. It is obvious that this operation is very time-consuming. As generally known, AFM force curve represents the relationship between the piezo scanner displacement in z-axis and the deflection of the cantilever. Thus the topography images consisted of the vertical displacements of the scanner and the deflection images can be combined to investigate some features of the force curve. The deflection set-point is set to be a time-varying value for increasing the range of scanning data. It is assumed that the elasticity is continuous in a small neighborhood of a scanning point, then a Kalman filter is utilized for conducting data fusion in the neighborhood and estimating the elasticity of the sample.
{"title":"A varying set-point AFM scanning method for simultaneous measurement of sample topography and elasticity","authors":"Xiaozhe Yuan, Yongchun Fang","doi":"10.1109/3M-NANO.2017.8286296","DOIUrl":"https://doi.org/10.1109/3M-NANO.2017.8286296","url":null,"abstract":"Atomic force microscopy (AFM) is a powerful tool for measuring the topography and mechanical properties in nano-scale. The topography of the sample can be achieved by contact mode scanning, while the mechanical properties can be investigated with the help of force curve. However the force curve characterizes the mechanical properties of the sample at a certain point. In many cases, it is important to get the elasticity distribution of the entire surface, which means a huge amount of points need to be selected for measuring force curves. It is obvious that this operation is very time-consuming. As generally known, AFM force curve represents the relationship between the piezo scanner displacement in z-axis and the deflection of the cantilever. Thus the topography images consisted of the vertical displacements of the scanner and the deflection images can be combined to investigate some features of the force curve. The deflection set-point is set to be a time-varying value for increasing the range of scanning data. It is assumed that the elasticity is continuous in a small neighborhood of a scanning point, then a Kalman filter is utilized for conducting data fusion in the neighborhood and estimating the elasticity of the sample.","PeriodicalId":6582,"journal":{"name":"2017 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO)","volume":"9 1","pages":"305-310"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86744470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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