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2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII)最新文献

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Quantitative Measurement of Cell Surface Expression Via Magnetophoretic Cytometry 磁电泳细胞术定量测定细胞表面表达
Ozgun Civelekoglu, Ningquan Wang, Mert Boya, Tevhide Ozkaya-Ahmadov, Ruxiu Liu, A. F. Sarioglu
Identification of membrane antigens and measurement of their expression within a cell population is of fundamental importance to medical and biological studies. In this work, we present a cytometry approach that is based on magnetophoresis and distributed Coulter sensing in a microfluidic system. Our magnetophoretic cytometer offers quantitative analysis of cell membrane antigens on a portable and disposable platform compared to conventional flow cytometers, which are complex, expensive and large systems. Our tests with human breast cancer cells show the utility of our microfluidic device and its potential as a point-of-care instrument for biomedical testing.
膜抗原的鉴定和测定其在细胞群中的表达对医学和生物学研究具有重要意义。在这项工作中,我们提出了一种在微流体系统中基于磁泳术和分布式库尔特传感的细胞计数方法。与复杂、昂贵和大型系统的传统流式细胞仪相比,我们的磁电泳细胞仪在便携式和一次性平台上提供细胞膜抗原的定量分析。我们对人类乳腺癌细胞的测试显示了我们的微流体装置的实用性及其作为生物医学测试的即时护理仪器的潜力。
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引用次数: 1
MEMS Based Particle Size Analyzer Using Electrostatic Measuring Techniques 基于静电测量技术的MEMS粒度分析仪
Sang-Myun Lee, Hong-Lae Kim, H. Kwon, Kyong-Gi Kim, S. Yoo, U. Hong, Jungho Hwang, Yong-Jun Kim
This paper reports a MEMS based particle size analyzer using electrostatic measuring techniques. The MEMS based particle size analyzer is able to classify particles of same diameter by using electrical mobility and measure particle size distribution in the size range of 50 to 300 nm. The performance of the proposed device was evaluated through measurements of particle size distribution and compared with commercial high precision instruments.
本文报道了一种基于微机电系统的静电测量粒度分析仪。基于MEMS的粒度分析仪能够利用电迁移率对相同直径的颗粒进行分类,并测量50至300 nm尺寸范围内的粒度分布。该装置的性能通过测量粒度分布进行了评估,并与商用高精度仪器进行了比较。
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引用次数: 2
Highly Sensitive and Selective Hydrogen Gas Sensor with Platinum Nanoparticles Linked by 4,4"-Diamino-P-Terphenyl (Dater) 由4,4"-二氨基-对三苯基(水)连接的铂纳米颗粒制成的高灵敏度和选择性氢气传感器
A. S. Pranti, Daniel Loof, S. Kunz, V. Zielasek, M. Bäumer, W. Lang
This paper presents a highly sensitive combustible gas sensor for detecting hydrogen gas selectively against other combustible gases. Ligands, 4,4"-Diamino-p-terphenyl (DATER), linked Pt nanoparticles are used for the first time as a catalyst for hydrogen gas detection. The sensor has very high sensitivity, 31 mV for 0.1% hydrogen at 110 °C operating temperature and shows completely linear characteristics with the concentration of hydrogen. It consumes extremely low power while operating at lower temperature, 14 mW at 90 °C. Moreover, the sensor has no cross-sensitivity to methane and ethane at its operating temperature as well as at higher temperature.
本文介绍了一种高灵敏度的可燃气体传感器,用于选择性地检测氢气和其他可燃气体。配体,4,4”-二氨基对terphenyl (DATER),连接Pt纳米颗粒首次被用作氢气检测的催化剂。该传感器具有非常高的灵敏度,在110°C工作温度下,对0.1%的氢气具有31 mV的灵敏度,并且与氢气浓度呈完全线性特性。它在较低温度下工作时消耗极低的功率,90°C时为14 mW。此外,该传感器在其工作温度和更高温度下对甲烷和乙烷没有交叉灵敏度。
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引用次数: 2
In-Planta Nitrate Detection Using Insertable Plant Microsensor 可插入植物微传感器的植物内硝酸盐检测
Yueyi Jiao, Xinran Wang, Yuncong Chen, M. Castellano, James c. Schnable, P. Schnable, Liang Dong
This paper reports a nutrient microsensor for in-situ detection of nitrate concentration inside plants. The sensor is inserted into the stalk of maize plant for continuous monitoring of dynamic nitrate uptake of the plant. The inserted part of the sensor consists of a nitrate sensing unit that works on the principle of chemical sensitive field effect transistor (chemFET), an integrated metallic thin-film thermorist, and a microscale reference electrode. The sensor enables measurement of nitrate concentration variations under different environmental conditions (e.g., light condition) and irrigation and fertigtation management. This device offers a new method to continuously detect and quantify nitrate levels inside the plants.
本文报道了一种用于植物体内硝酸盐浓度原位检测的营养微传感器。该传感器插入玉米植株的茎秆中,连续监测植株对硝酸盐的动态吸收。传感器的插入部分由一个基于化学敏感场效应晶体管(chemFET)原理的硝酸盐传感单元、一个集成的金属薄膜热敏器和一个微尺度参比电极组成。该传感器能够测量不同环境条件(例如光照条件)和灌溉和施肥管理下的硝酸盐浓度变化。该装置提供了一种连续检测和量化植物内部硝酸盐水平的新方法。
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引用次数: 2
Grating-Based Acceleration Sensors with Optical Interferometric Readout and Closed-Loop Control 基于光栅的光干涉读出和闭环控制加速度传感器
Randall P. Williams, N. Hall, B. Avenson
We have developed an optically-read inertial sensor, where microfabricated diffractive optics are used to read the displacement of a macroscale proof mass. The measured noise floor of the sensor is 3 ng/√Hz from 0.1 Hz to 100 Hz. Feedback is implemented with a macroscale motor coil and rare earth magnets, achieving a dynamic range of 176 dB. This allows the sensor to target planetary seismic applications, with field expeditions completed in Alaska and Greenland. Optical models were developed to explore the optical design space, resulting in innovate stepped grating designs which will facilitate optoelectronic integration for microscale devices.
我们开发了一种光学读取惯性传感器,其中微加工衍射光学元件用于读取宏观尺度证明质量的位移。在0.1 Hz ~ 100hz范围内测得传感器的本底噪声为3ng /√Hz。反馈是由一个宏观电机线圈和稀土磁铁实现的,实现了176 dB的动态范围。这使得传感器能够针对行星地震应用,在阿拉斯加和格陵兰岛完成实地考察。开发光学模型以探索光学设计空间,从而产生创新的阶梯光栅设计,这将促进微尺度器件的光电集成。
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引用次数: 5
Acoustic Propeller Based on Air Jets from Acoustic Streaming 基于声流空气射流的声学螺旋桨
Yongkui Tang, E. S. Kim
This paper describes acoustic thruster and lifter capable of generating propulsion force on-demand from synthetic air jets generated by acoustic waves passing through orifices on a thin plastic (shaped with laser-machining) covering a sound source (audio speaker). The orifice array pattern was optimized through experiments to produce large thrust force. By varying driving condition and operating frequency, the transducer that weighs 603 mg can rotate, or jump 2.8 mm high and 100 mm far, propelled by the air jets. When tested as an acoustic lifter, the transducer is capable of lifting a plastic piece of 299 mg and rotating a metal piece of 20.4 g. The device could also be driven with acoustic signal instead of electrical power.
本文描述了声波通过覆盖声源(扬声器)的薄塑料(用激光加工成型)上的孔所产生的合成空气射流产生按需推进力的声学推力器和升力器。通过实验优化了孔板排列方式,以产生较大的推力。通过改变驱动条件和工作频率,重603毫克的换能器可以在空气射流的推动下旋转或跳跃2.8毫米高100毫米远。当作为声学提升器进行测试时,换能器能够提升299毫克的塑料片和旋转20.4克的金属片。该装置也可以用声信号而不是电力来驱动。
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引用次数: 1
Low-Melting Alloy Microfluidic Electrode Based on Hydrophobic Valve and its Application in Coulter Counter 基于疏水阀的低熔点合金微流控电极及其在Coulter计数器中的应用
Dong Yang, Wenpeng Xun, H. Feng, Honglong Chang
This paper presents a new method to fabricate low-melting point alloy (LMPA) electrodes inside polydimethylsiloxane (PDMS) microfluidic channels. The melting alloy is injected into a subchannel designed as a hydrophobic valve, which provides a threshold pressure to flow through. Thus, with an appropriate control of the injecting pressure, the melting alloy can fully fill the subchannel without passing through it and blocking the main channel. After the solidification, an LMPA microelectrode is formed and automatically aligned on the side of main channel. A Coulter counter microfluidic chip is fabricated using this method and a coefficient variation (CV) of 1.99% is obtained for 10-μm beads. The results show that the proposed method is a feasible solution to fabricate robust microelectrodes in polymer-based microfluidic chips without the expensive lithography or sputtering.
提出了一种在聚二甲基硅氧烷(PDMS)微流控通道内制备低熔点合金(LMPA)电极的新方法。熔化的合金被注入到设计为疏水阀的子通道中,该子通道提供了流过的阈值压力。因此,在适当控制注射压力的情况下,熔化的合金可以充分填充子通道,而不会穿过子通道而阻塞主通道。凝固后形成LMPA微电极,并在主通道侧自动对准。用该方法制备了库尔特计数器微流控芯片,在10 μm微珠上的变异系数(CV)为1.99%。结果表明,该方法是在聚合物基微流控芯片上制备鲁棒微电极的可行方案,无需昂贵的光刻或溅射工艺。
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引用次数: 2
A Highly Sensitive Capacitive Pressure Sensor with Microdome Structure for Robot Tactile Detection 一种用于机器人触觉检测的微球结构高灵敏度电容式压力传感器
Shan Wang, Kuan-Hua Huang, Y. Yang
This work presents a polymer-based capacitive sensor array capable of measuring both normal and shear forces. The capacitive sensing element consists of polydimethylsiloxane (PDMS) dielectric layers and gold electrode arrays. The PDMS dielectric layers were patterned with microdome structures using a simple micromachining technique with nylon membrane filters. Further, by using membranes with different pore sizes, the pressure sensitivity of the capacitive tactile sensor can be adjusted with ease. The measured relationship of capacitance versus pressure indicates that the sensitivity of sensors with interlocked interfaces is much higher than that of the sensor with planar films.
这项工作提出了一种基于聚合物的电容式传感器阵列,能够测量法向和剪切力。电容式传感元件由聚二甲基硅氧烷(PDMS)介电层和金电极阵列组成。采用简单的尼龙膜过滤器微加工技术在PDMS介电层上制作了微圆顶结构。此外,通过使用不同孔径的膜,电容式触觉传感器的压力灵敏度可以轻松调节。测得的电容与压力的关系表明,具有互锁界面的传感器的灵敏度远远高于具有平面薄膜的传感器。
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引用次数: 15
Multiparametric, Spatially Resolved Detection of H2O2 and O2 with Electrochemical Microsensor Array in Synthesis Membrane Microreactors 电化学微传感器阵列在合成膜微反应器中多参数、空间分辨检测H2O2和O2
Sebastian Urban, J. Kieninger, Benedikt J. Deschner, M. Kraut, R. Dittmeyer, G. Urban, A. Weltin
We present an electrochemical microsensor system for the multiparametric detection of dissolved concentrations of hydrogen peroxide (H2O2) and oxygen (O2) inside a direct synthesis membrane microreactor. Both reactants are detected with high sensitivity on the same Pt-based electrode by changing the applied measurement potential in a chronoamperometric protocol. The robust integration of the electrochemical cell in the microreactor was demonstrated and allowed for in situ detection of the spatial gradient of the changing oxygen concentration diffusing through a membrane into the microreactor, emphasizing the capabilities of our monitoring system.
我们提出了一种电化学微传感器系统,用于直接合成膜微反应器内过氧化氢(H2O2)和氧气(O2)溶解浓度的多参数检测。通过改变计时安培方案中应用的测量电位,在相同的pet电极上以高灵敏度检测两种反应物。电化学电池在微反应器中的强大集成得到了证明,并允许对通过膜扩散到微反应器的氧气浓度变化的空间梯度进行原位检测,强调了我们的监测系统的能力。
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引用次数: 3
Untethered Soft Robots with Bioinspired Bone-and-Flesh Constructs for Fast Deterministic Actuation 无系绳软机器人与生物启发的骨和肉结构的快速确定性驱动
Renxiao Xu, Fanping Sui, Gaurav Jalan, Pinghsun Lee, Liangjie Ren, M. Sanghadasa, Liwei Lin
We present a new class of soft robots inspired by the bone-and-flesh construct in human body for fast, deterministic actuation. Two distinctive advancements have been achieved: (1) untethered robots with external magnetic power, boasting high normalized power density of ~2*10-2/s (40-6,000,000× higher than most reports); (2) ultrafast and deterministic-shape actuation in ~0.1 seconds (100x faster than the state-of-the-art). Inspired by the natural human architecture, our soft robots with different elastomer ("flesh") structures and magnet ("bone") placements can complete various tasks quickly and precisely (e.g., planar contraction, out-of-plane gesture transitions, breaking lock-in states, and manipulating small objects). We envision that our design and operation principles can be potentially extended to even more complex applications.
我们提出了一种新型的软体机器人,灵感来自于人体的骨和肉结构,用于快速,确定的驱动。取得了两项显著进展:(1)具有外磁动力的无系机器人,具有高归一化功率密度~2*10-2/s(比大多数报道高40-6,000,000倍);(2)在0.1秒内实现超快速和确定形状的驱动(比目前最先进的速度快100倍)。受自然人类建筑的启发,我们的软体机器人具有不同的弹性体(“肉”)结构和磁铁(“骨头”)位置,可以快速准确地完成各种任务(例如,平面收缩,平面外手势转换,打破锁定状态,操纵小物体)。我们设想我们的设计和操作原则可以潜在地扩展到更复杂的应用程序中。
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引用次数: 1
期刊
2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII)
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