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Sordera infantil con discapacidad asociada (DA+): recomendaciones CODEPEH 儿童耳聋与相关残疾(ad +): CODEPEH建议
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-11-01 DOI: 10.1016/j.otorri.2022.10.003
Faustino Núñez-Batalla , Carmen Jáudenes-Casaubón , Jose Miguel Sequí-Canet , Ana Vivanco-Allende , Jose Zubicaray-Ugarteche

Approximately 40% of children with deafness have an additional developmental disorder or major medical problem, which may delay the age of diagnosis of hearing loss and/or require intervention by other professionals. This situation is referred to as “deafness with added disability” (AD+). The reason why the population of hearing-impaired children is more likely to have associated added disabilities is that the risk factors for hearing impairment overlap with those for many other disabilities. These factors can influence various aspects of development, including language acquisition. It is important to check that appropriate care is received, the effectiveness of hearing aids or implants, as well speech therapy intervention strategies, and family adherence to sessions and appointments. The challenge posed by AD+ is early detection, to allow early and appropriate intervention, and the need for fluid transdisciplinary collaboration between all professionals involved, together with the involvement of the family.

大约40%的耳聋儿童有额外的发育障碍或重大的医疗问题,这可能会延迟听力损失的诊断年龄和/或需要其他专业人员的干预。这种情况被称为“附加残疾聋”(AD+)。听力受损儿童更有可能伴有附加残疾的原因是,听力受损的风险因素与许多其他残疾的风险因素重叠。这些因素可以影响发展的各个方面,包括语言习得。重要的是要检查是否接受了适当的护理,助听器或植入物的有效性,以及言语治疗干预策略,以及家庭对会议和预约的依从性。AD+带来的挑战是早期发现,以便及早和适当干预,需要所有相关专业人员之间的流畅的跨学科合作,以及家庭的参与。
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引用次数: 0
Ausencia de hipersensibilidad al efecto ototóxico de la gentamicina en un paciente portador de la mutación 1555A > G en el gen MT-RNR1 MT-RNR1基因1555A > G突变患者对庆大霉素耳毒性作用无过敏反应
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-11-01 DOI: 10.1016/j.otorri.2023.03.002
Cristina Salomón Felechosa , Jaime Gallo Terán , Carmelo Morales-Angulo
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引用次数: 0
Postintubation airway injury in the pediatric intensive care unit 儿科重症监护病房插管后气道损伤
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-11-01 DOI: 10.1016/j.otorri.2022.12.004
Otilia E. Blain, Celeste C. Patiño González, Enrique J. Romero Manteola

Introduction and objectives

Airway injury caused by endotracheal intubation (ETI) is a common event in children who require ETI in the pediatric intensive care unit (PICU). The main aim of our study was to determine the incidence and the predisposing factors for the development of airway injury in PICU patients who need ETI. Secondary objectives were to evaluate the reasons for the request of airway endoscopy examination and the tracheostomy rate in this population.

Materials and methods

A retrospective, observational, descriptive study was conducted evaluating 1854 patients who were intubated in the PICU of a tertiary-care center between May 2015 and April 2019.

Results

The mean age of all intubated patients was 35.6 months and of those who required endoscopy 27.3 months (p = 0.04). Mean length of intubation was 7.2 days for all intubated patients and 23.5 days for those who required endoscopy (p = 0.0001). Extubation failure and stridor were significantly associated with the finding of airway injury (p = 0.0001 and p = 0.0006, respectively).

Conclusions

The incidence rate of ETI-related injury was 3%. Age younger than 27 months and intubation for more than 7 days were predisposing factors for the development of injury.

The main indications for endoscopy were extubation failure and stridor, both related to the presence of injury. Tracheostomy rate in the PICU was 3.34%.

引言和目的气管插管(ETI)引起的气道损伤是儿童重症监护室(PICU)需要ETI的常见事件。我们研究的主要目的是确定需要ETI的PICU患者气道损伤的发生率和易感因素。次要目的是评估该人群要求进行气道内窥镜检查的原因和气管造口率。材料和方法回顾性、观察性、,对2015年5月至2019年4月期间在三级护理中心PICU插管的1854名患者进行了描述性研究。结果所有插管患者的平均年龄为35.6个月,需要内窥镜检查的患者为27.3个月(p=0.04)。所有插管患者和需要内窥镜检查的患者的平均插管时间分别为7.2天和23.5天(p=0.0001)。拔管失败和喘鸣与气道损伤的发现显著相关(分别为p=0.0001和p=0.0006)。结论ETI相关损伤的发生率为3%。年龄小于27个月和插管时间超过7天是发生损伤的易感因素。内窥镜检查的主要指征是拔管失败和喘鸣,两者都与损伤有关。PICU的气管造口率为3.34%。
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引用次数: 0
Quality of life after revision mastoidectomy with mastoid obliteration 改良乳突切除术合并乳突闭塞术后的生活质量
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-11-01 DOI: 10.1016/j.otorri.2023.02.001
Vito Pontillo, Sabino Ciprelli, Rossella Grillo, Nicola Quaranta

Aims

To evaluate the postoperative quality of life (QoL) after revision canal wall down mastoidectomy with mastoid obliteration (rCWD).

Material and methods

A retrospective analysis was conducted on patients treated by rCWD for cholesteatoma between 2016 and 2019. A control group including all patients treated by primary canal wall down with mastoid obliteration (pCWD) for cholesteatoma between 2009 and 2014 was used for the comparison of the postoperative QoL, assessed by the COMQ-12.

Results

The rCWD and pCWD groups respectively counted 38 and 78 patients with an average follow-up of 30 and 62 months respectively. No significant difference was found in terms of QoL between the two groups. An intra-group analysis among rCWD patients, showed that patients treated by canal wall down (CWD) at the primary surgery had a significantly worse post-revision QoL compared to those initially treated by canal wall up (CWU), specifically in the hearing and balance domains of the questionnaire.

Conclusions

Revision mastoid obliteration leads to similar QoL results to those obtained after primary CWD with obliteration. Patients who had undergone a CWD as primary surgery complain worse hearing and balance problems compared to those primarily submitted to CWU, even after revision surgery.

目的评估乳突管壁下乳突切除术后的生活质量。材料和方法对2016年至2019年期间接受rCWD治疗的胆脂瘤患者进行回顾性分析。对照组包括2009年至2014年间因胆脂瘤接受乳腺切除术(pCWD)治疗的所有患者,用于比较术后生活质量,通过COMQ-12进行评估。两组患者的生活质量无显著差异。一项针对rCWD患者的组内分析显示,与最初接受管壁抬高(CWU)治疗的患者相比,在初次手术时接受管壁压低(CWD)治疗的病人在翻修后生活质量明显较差,特别是在问卷的听力和平衡领域。结论乳腺切除术后的生活质量与原发性CWD后的结果相似。与最初接受CWU治疗的患者相比,在初次手术中接受CWD治疗的患者抱怨听力和平衡问题更糟,即使在翻修手术后也是如此。
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引用次数: 0
Sinonasal mucormycosis during 2 years of COVID-19 pandemic in central Iran: incidence rate and clinical features 伊朗中部2年COVID-19大流行期间鼻粘膜真菌病的发病率和临床特征
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.otorri.2022.11.001
Mohammadhossein Dadgarnia, Mohammad Mandegari, Mohammadhossein Baradaranfar, Sedighe Vaziribozorg, Mahsa Abdollahpour

Introduction

As a novel infectious disease, COVID-19 is caused by SARS-COV-2, spreading rapidly worldwide. ENT specialists have faced this challenging disease in various ways since the emergence of the COVID-19 pandemic. We are currently facing an increase in cases referred due to sinonasal mucormycosis which is a rare but invasive, rapidly progressive, and life-threatening infection. We provide an overview of this disease's incidence rate and clinical features.

Methods

This descriptive cross-sectional study was conducted on 46 sinonasal mucormycosis patients who were histopathologically confirmed after sinonasal endoscopic surgery in our educational therapeutic hospital during 2 years of the COVID-19 pandemic from March 20, 2020, to March 20, 2022.

Results

There was an increase in the incidence of mucormycosis more than twice as much as before. All patients had a history of COVID-19 and 69.6% were diabetic. The median time to symptom onset from COVID-19 detection was 3.3 weeks. A total of 60.9% received steroids while 85.7% were prescribed during COVID-19 treatment. The most common manifestation was orbital involvement (80.4%). Of the 46 study cases, unfortunately, 17 (37%) died. An exciting point in our study was the incidence of peripheral facial palsy which is associated involvement of multiple other cranial nerves (II, III, IV, V, VI) considered to be the likely occurrence of a rare phenomenon called Garcin's syndrome.

Conclusion

Based on the results of this study, during 2 years of the COVID -19 pandemic, there was an increase in the incidence of sinonasal mucormycosis more than twice as much as before.

简介新冠肺炎是由严重急性呼吸系统综合征冠状病毒2型引起的一种新型传染病,在全球范围内迅速传播。自从新冠肺炎大流行出现以来,耳鼻喉科专家以各种方式面对这种具有挑战性的疾病。我们目前面临着鼻腔毛霉菌病转诊病例的增加,这是一种罕见但侵袭性强、进展迅速且危及生命的感染。我们提供了这种疾病的发病率和临床特征的概述。方法对新冠肺炎大流行2年(2020年3月20日至2 0 2年3月2日)期间在我院教育治疗医院经鼻窦内窥镜手术病理证实的46例鼻腔毛霉菌病患者进行描述性横断面研究。所有患者都有新冠肺炎病史,69.6%患有糖尿病。从新冠肺炎检测到症状出现的中位时间为3.3周。共有60.9%的患者接受了类固醇治疗,85.7%的患者在新冠肺炎治疗期间服用了处方。最常见的表现是眼眶受累(80.4%)。在46例研究病例中,不幸的是,17例(37%)死亡。在我们的研究中,一个令人兴奋的点是周围性面瘫的发生率,它与多个其他颅神经(II、III、IV、V、VI)有关,被认为是一种罕见现象Garcin综合征的可能发生。结论根据本研究结果,在COVID-19大流行的2年中,鼻腔毛霉菌病的发病率比以前增加了一倍多。
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引用次数: 0
Upper airway assessment in obstructive sleep apnea patients: can computed tomography with lateral cephalometry replace drug-induced sleep endoscopy (DISE)? 阻塞性睡眠呼吸暂停患者的上呼吸道评估:计算机断层扫描与侧位头测量术能否取代药物诱导睡眠内窥镜(DISE)?
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.otorri.2022.10.004
Ana Campos , Pedro Cebola , Sara Simões Dias , José Pedro Pais , Susana Sousa , Sérgio Cardoso , João Paço , Cristina Caroça

Objective

To evaluate the association between results from drug-induced sleep endoscopy (DISE) and computed tomography with lateral cephalometry (CTLC) of the pharynx in obstructive sleep apnea (OSA) patients, regarding the same anatomic level, in order to understand if CTLC could replace DISE in selected patients.

Study design

Cross-sectional.

Setting

Tertiary hospital.

Methods

A total of 71 patients who attended the Sleep Medicine Consultation in the Otorhinolaryngology Department of Hospital CUF Tejo between 1.6.2019 and 30.9.2021, performed a polysomnographic sleep study and were elected to undergo DISE and CTLC of the pharynx for diagnostic purposes were selected. Obstructions at the same anatomic levels – tongue base, epiglottis and velum - were compared in both exams.

Results

Patients with reduction of epiglottis-pharynx space on CTLC had also a complete obstruction at epiglottis level on the VOTE classification of DISE (p = 0,027). Reduction of velum-pharynx space or tongue base-pharynx space were not related to complete obstruction of the velum (P = 0,623) or the tongue base (p = 0,594) found in DISE. Those with two or more space reductions had a tendency to multilevel obstruction observed in DISE (p = 0.089).

Conclusion

When evaluating the obstruction level(s) of an OSA patient, efforts should be made to perform DISE, since CTLC measures, though regarding at the same structures, don´t correlate completely with obstructions observed in DISE.

目的在相同的解剖水平上,评估阻塞性睡眠呼吸暂停(OSA)患者药物诱导睡眠内窥镜(DISE)和咽侧头影计算机断层扫描(CTLC)结果之间的相关性,以了解CTLC是否可以取代选定患者的DISE。研究设计跨学科设置三级医院。方法选择在2019年6月1日至2021年9月30日期间参加了CUF Tejo医院耳鼻咽喉科睡眠医学咨询的71名患者,进行了多导睡眠图研究,并选择他们进行了DISE和咽CTLC诊断。在两次检查中,对相同解剖水平(舌根、会厌和硬脑膜)的梗阻进行了比较。结果CTLC会厌咽间隙缩小的患者在DISE的VOTE分级上也有会厌水平的完全阻塞(p = 0027)。咽膜间隙缩小或舌基咽间隙缩小与咽膜完全阻塞无关(P = 0623)或舌根(p = 0594)。有两次或两次以上空间缩小的患者在DISE中有多级阻塞的趋势(p = 0.089)。结论在评估OSA患者的阻塞程度时,应努力进行DISE,因为CTLC测量虽然涉及相同的结构,但与DISE中观察到的阻塞并不完全相关。
{"title":"Upper airway assessment in obstructive sleep apnea patients: can computed tomography with lateral cephalometry replace drug-induced sleep endoscopy (DISE)?","authors":"Ana Campos ,&nbsp;Pedro Cebola ,&nbsp;Sara Simões Dias ,&nbsp;José Pedro Pais ,&nbsp;Susana Sousa ,&nbsp;Sérgio Cardoso ,&nbsp;João Paço ,&nbsp;Cristina Caroça","doi":"10.1016/j.otorri.2022.10.004","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.10.004","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the association between results from drug-induced sleep endoscopy<span><span> (DISE) and computed tomography<span> with lateral cephalometry (CTLC) of the </span></span>pharynx<span> in obstructive sleep apnea (OSA) patients, regarding the same anatomic level, in order to understand if CTLC could replace DISE in selected patients.</span></span></p></div><div><h3>Study design</h3><p>Cross-sectional.</p></div><div><h3>Setting</h3><p>Tertiary hospital.</p></div><div><h3>Methods</h3><p>A total of 71 patients who attended the Sleep Medicine<span> Consultation in the Otorhinolaryngology<span><span> Department of Hospital CUF Tejo between 1.6.2019 and 30.9.2021, performed a polysomnographic sleep study and were elected to undergo DISE and CTLC of the pharynx for diagnostic purposes were selected. Obstructions at the same anatomic levels – tongue base, </span>epiglottis and velum - were compared in both exams.</span></span></p></div><div><h3>Results</h3><p>Patients with reduction of epiglottis-pharynx space on CTLC had also a complete obstruction at epiglottis level on the VOTE classification of DISE (p = 0,027). Reduction of velum-pharynx space or tongue base-pharynx space were not related to complete obstruction of the velum (P = 0,623) or the tongue base (p = 0,594) found in DISE. Those with two or more space reductions had a tendency to multilevel obstruction observed in DISE (p = 0.089).</p></div><div><h3>Conclusion</h3><p>When evaluating the obstruction level(s) of an OSA patient, efforts should be made to perform DISE, since CTLC measures, though regarding at the same structures, don´t correlate completely with obstructions observed in DISE.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"74 5","pages":"Pages 290-297"},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49779239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cribado auditivo neonatal universal e hipoacusia diferida o de desarrollo tardío 新生儿听力筛查与延迟或晚期发育性听力损失
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.otorri.2022.10.001
Faustino José Núñez Batalla , Carmen Fernández-Cedrón Bermejo , Maite Guntín García , Isabel Sandoval Menéndez , Estefanía Fresno Díaz , Justo Ramón Gómez Martínez , José Luis Llorente Pendás

Objective

To determine the percentage of children with permanent bilateral postnatal hearing loss in order to study its incidence, related risk factors, diagnosis and treatment.

Methods

Retrospective study to collect data on children diagnosed with hearing loss outside the neonatal period in the Hearing Loss Unit of the Hospital Universitario Central de Asturias, from April 2014 to April 2021.

Results

52 cases met the inclusion criteria. The detection rate of congenital hearing loss in the neonatal screening programme in the same study period was 1.5 children per thousand newborns per year, adding postnatal hearing loss results in a rate of infant bilateral hearing loss of 2.7 children per thousand (55.5% and 44.4% respectively). Thirty-five children presented risk factors for hearing loss, of which 23 were at retrocochlear risk. The mean age at referral was 91.9 (18-185) months. Hearing aid fitting was indicated in 44 cases (84.6%). Cochlear implantation was indicated in eight cases (15.4%).

Discussion

Although congenital hearing loss accounts for the majority of childhood deafness, postnatal hearing loss has a significant incidence. This may be mainly due to: 1) that hearing impairment may arise in the first years of life, 2) that mild hearing loss as well as hearing loss in severe frequencies are undetectable by neonatal screening in some cases, 3) that some children may have false negative results.

Conclusion

Postnatal hearing loss requires identification of risk factors and long-term follow-up of children with hearing loss, as it needs to be detected and treated early.

目的确定出生后双侧永久性听力损失患儿的比例,探讨其发生率、相关危险因素、诊断和治疗。方法回顾性研究收集2014年4月至2021年4月在阿斯图里亚斯中央大学医院听力损失科诊断为新生儿期外听力损失的儿童的数据。结果52例符合纳入标准。在同一研究期间的新生儿筛查计划中,先天性听力损失的检出率为每年每千名新生儿1.5个孩子,加上产后听力损失,婴儿双侧听力损失的发生率为每千名婴儿2.7个孩子(分别为55.5%和44.4%)。35名儿童存在听力损失的危险因素,其中23名存在耳蜗后风险。转诊时的平均年龄为91.9(18-185)个月。44例(84.6%)需要佩戴助听器。8例(15.4%)需要人工耳蜗植入。讨论尽管先天性听力损失占儿童耳聋的大多数,但产后听力损失的发生率很高。这可能主要是由于:1)在生命的最初几年可能会出现听力损伤,2)在某些情况下,新生儿筛查无法检测到轻度听力损失和严重频率的听力损失,3)一些儿童可能会出现假阴性结果。结论产后听力损失需要识别风险因素,并对听力损失儿童进行长期随访,因为它需要早期发现和治疗。
{"title":"Cribado auditivo neonatal universal e hipoacusia diferida o de desarrollo tardío","authors":"Faustino José Núñez Batalla ,&nbsp;Carmen Fernández-Cedrón Bermejo ,&nbsp;Maite Guntín García ,&nbsp;Isabel Sandoval Menéndez ,&nbsp;Estefanía Fresno Díaz ,&nbsp;Justo Ramón Gómez Martínez ,&nbsp;José Luis Llorente Pendás","doi":"10.1016/j.otorri.2022.10.001","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.10.001","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the percentage of children with permanent bilateral postnatal hearing loss in order to study its incidence, related risk factors, diagnosis and treatment.</p></div><div><h3>Methods</h3><p>Retrospective study to collect data on children diagnosed with hearing loss outside the neonatal period in the Hearing Loss Unit of the Hospital Universitario Central de Asturias, from April 2014 to April 2021.</p></div><div><h3>Results</h3><p>52 cases met the inclusion criteria. The detection rate of congenital hearing loss in the neonatal screening programme in the same study period was 1.5 children per thousand newborns per year, adding postnatal hearing loss results in a rate of infant bilateral hearing loss of 2.7 children per thousand (55.5% and 44.4% respectively). Thirty-five children presented risk factors for hearing loss, of which 23 were at retrocochlear risk. The mean age at referral was 91.9 (18-185) months. Hearing aid fitting was indicated in 44 cases (84.6%). Cochlear implantation was indicated in eight cases (15.4%).</p></div><div><h3>Discussion</h3><p>Although congenital hearing loss accounts for the majority of childhood deafness, postnatal hearing loss has a significant incidence. This may be mainly due to: 1) that hearing impairment may arise in the first years of life, 2) that mild hearing loss as well as hearing loss in severe frequencies are undetectable by neonatal screening in some cases, 3) that some children may have false negative results.</p></div><div><h3>Conclusion</h3><p>Postnatal hearing loss requires identification of risk factors and long-term follow-up of children with hearing loss, as it needs to be detected and treated early.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"74 5","pages":"Pages 283-289"},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49779240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Presentación inusual de un linfoma MALT 麦芽淋巴瘤的不寻常表现
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.otorri.2022.05.003
Natalia Gordillo Gayo, María Antón Almero, Marta Faubel Serra
{"title":"Presentación inusual de un linfoma MALT","authors":"Natalia Gordillo Gayo,&nbsp;María Antón Almero,&nbsp;Marta Faubel Serra","doi":"10.1016/j.otorri.2022.05.003","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.05.003","url":null,"abstract":"","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"74 5","pages":"Pages 336-337"},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49779238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of von Willebrand factor and protein/creatinine ratio in idiopathic sudden hearing loss 特发性突发性听力损失中血管性血友病因子和蛋白/肌酐比值的评价
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.otorri.2022.09.002
Özge Çaglar Çil , Serkan Bakirdögen , Dilek Ülker Çakir , Hasan Gül , Sibel Oymak

Objective

The objective of this study was to evaluate the levels of von Willebraund Factor (vWF) in plasma and the protein/creatinine ratio in urine in patients with idiopathic sudden acute hearing loss, which we think to be caused by epithelial dysfunction.

Materials-Methods

Thirty patients with a sudden hearing loss and thirty healthy individuals were included in the study. Before the treatment, blood and urine were collected from the patients and the control group to investigate the levels of the protein/creatinine ratio and the levels of vWF. The test results of the patients group were compared with those of the control group.

Results

We found that the levels of vWF increased in the patient group, which was statistically significant (P < .05). The protein/creatinine ratio in the urine increased in the patient group, but this was not statistically significant (P > .05). In addition, we found that the vWF and urine protein/creatin ratio of the patients who benefited from treatment were lower than those who did not benefit.

Conclusions

This study showed that sudden sensorineural hearing loss may result from endothelial dysfunction. However, more studies that include more patients are needed in order to support this.

目的评价特发性突发性急性听力损失患者血浆血管性血友病因子(vWF)水平和尿蛋白/肌酐比值,我们认为这是上皮功能障碍引起的。材料-方法选取30例突发性听力损失患者和30例健康人作为研究对象。治疗前分别采集患者和对照组的血、尿,检测蛋白/肌酐比值和vWF水平。将患者组的检测结果与对照组进行比较。结果患者组vWF水平升高,差异有统计学意义(P <.05). 患者组尿中蛋白/肌酐比值升高,但无统计学意义(P >.05). 此外,我们发现受益于治疗的患者的vWF和尿蛋白/生成比低于未受益的患者。结论突发性感音神经性听力损失可能由内皮功能障碍引起。然而,为了支持这一点,需要更多的研究,包括更多的患者。
{"title":"Evaluation of von Willebrand factor and protein/creatinine ratio in idiopathic sudden hearing loss","authors":"Özge Çaglar Çil ,&nbsp;Serkan Bakirdögen ,&nbsp;Dilek Ülker Çakir ,&nbsp;Hasan Gül ,&nbsp;Sibel Oymak","doi":"10.1016/j.otorri.2022.09.002","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>The objective of this study was to evaluate the levels of von Willebraund Factor (vWF) in plasma and the protein/creatinine ratio in urine in patients with idiopathic sudden acute hearing loss, which we think to be caused by epithelial dysfunction.</p></div><div><h3>Materials-Methods</h3><p><span>Thirty patients with a sudden hearing loss and thirty healthy individuals were included in the study. Before the </span>treatment, blood and urine were collected from the patients and the control group to investigate the levels of the protein/creatinine ratio and the levels of vWF. The test results of the patients group were compared with those of the control group.</p></div><div><h3>Results</h3><p>We found that the levels of vWF increased in the patient group, which was statistically significant (<em>P</em> <!-->&lt;<!--> <!-->.05). The protein/creatinine ratio in the urine increased in the patient group, but this was not statistically significant (<em>P</em> <!-->&gt;<!--> <!-->.05). In addition, we found that the vWF and urine protein/creatin ratio of the patients who benefited from treatment were lower than those who did not benefit.</p></div><div><h3>Conclusions</h3><p>This study showed that sudden sensorineural hearing loss may result from endothelial dysfunction. However, more studies that include more patients are needed in order to support this.</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"74 5","pages":"Pages 277-282"},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49871867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Translation into Spanish and validation of the Tinnitus Functional Index (TFI) 耳鸣功能指数(TFI)的西班牙语翻译与验证
IF 1 Q3 OTORHINOLARYNGOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.otorri.2022.11.002
Maria Montserrat Soriano-Reixach , Juan José Navarro Sampedro , Miren Sonsoles Goiburu Minguez , Jorge Rey-Martínez , Xabier Altuna

Objective

The objectives of this study were to translate into Spanish, cross-culturally adapt and validate the TFI.

Materials and Methods

The TFI questionnaire translated into Spanish (Sp-TFI) and cross-culturally adapted following the published guidelines on cross-cultural adaptation of health questionnaires was evaluated using two indicators. Its internal consistency was assessed with Cronbach’s α considering the Tinnitus Handicap Inventory (THI) as the gold standard. Further, its test-retest reliability was assessed with intraclass correlation coefficients (ICCs). ICCs were also calculated for the THI and visual analogue scales (VAS) for tinnitus tested and retested in all participants.

Results

The mean age of the 18 participants was 45.77 (SD: 11.87) years; 12 were female (66.67 %) and 6 were male (33.33%). Half of the participants experienced tinnitus in their left ear and half in their right. The mean pure-tone average (PTA) in the affected ear was 29.34 (SD: 8.08) dB-HL. Regarding internal consistency and reliability of the Sp-TFI respectively, Cronbach’s α was 0.83 and the ICC type (2,1) was 1 (CI: 0.99–1). Among the variables studied, we found the following independent predictors had statistically significant effects on THI score: sex (p < 0.01), PTA (p = 0.03), overall Sp-TFI score (p = 0.02) and Sp-TFI SL, R and A subscale scores (p = 0.03, p = 0.03, and p < 0.01, respectively).

Conclusion

Based on the internal consistency and reliability results obtained in this study, the cross-culturally adapted Spanish version of the TFI (Sp-TFI) has been validated for use in Spain.

Level of evidence

2B: Individual cohort study/low-quality randomized control studies

本研究的目的是将TFI翻译成西班牙语,进行跨文化改编和验证。材料和方法根据已发布的跨文化适应健康问卷指南,将TFI问卷翻译成西班牙语(Sp-TFI)并进行跨文化适应,使用两个指标进行评估。以耳鸣障碍量表(THI)为金标准,用Cronbachα法评估其内部一致性。此外,用组内相关系数(ICCs)评估其重测可靠性。还计算了所有参与者耳鸣测试和重新测试的THI和视觉模拟量表(VAS)的ICCs。结果18名参与者的平均年龄为45.77岁(SD:11.87);12名女性(66.67%),6名男性(33.33%)。一半的参与者左耳耳鸣,一半右耳耳鸣。患耳的平均纯音平均值(PTA)为29.34(SD:8.08)dB HL。关于Sp-TFI的内部一致性和可靠性,Cronbachα为0.83,ICC类型(2,1)为1(CI:0.99-1)。在研究的变量中,我们发现以下独立预测因子对THI评分有统计学显著影响:性别(p <; 0.01)、PTA(p=0.03)、Sp-TFI总分(p=0.02)和Sp-TFI SL、R和A分量表得分(p=0.03,p = 0.03和p <; 分别为0.01)。结论基于本研究获得的内部一致性和可靠性结果,跨文化适应的西班牙语版TFI(Sp-TFI)已被验证可在西班牙使用。证据水平2B:个体队列研究/低质量随机对照研究
{"title":"Translation into Spanish and validation of the Tinnitus Functional Index (TFI)","authors":"Maria Montserrat Soriano-Reixach ,&nbsp;Juan José Navarro Sampedro ,&nbsp;Miren Sonsoles Goiburu Minguez ,&nbsp;Jorge Rey-Martínez ,&nbsp;Xabier Altuna","doi":"10.1016/j.otorri.2022.11.002","DOIUrl":"https://doi.org/10.1016/j.otorri.2022.11.002","url":null,"abstract":"<div><h3>Objective</h3><p>The objectives of this study were to translate into Spanish, cross-culturally adapt and validate the TFI.</p></div><div><h3>Materials and Methods</h3><p>The TFI questionnaire translated into Spanish (Sp-TFI) and cross-culturally adapted following the published guidelines on cross-cultural adaptation of health questionnaires was evaluated using two indicators. Its internal consistency was assessed with Cronbach’s α considering the Tinnitus Handicap Inventory (THI) as the gold standard. Further, its test-retest reliability was assessed with intraclass correlation coefficients (ICCs). ICCs were also calculated for the THI and visual analogue scales (VAS) for tinnitus tested and retested in all participants.</p></div><div><h3>Results</h3><p>The mean age of the 18 participants was 45.77 (SD: 11.87) years; 12 were female (66.67 %) and 6 were male (33.33%). Half of the participants experienced tinnitus in their left ear and half in their right. The mean pure-tone average (PTA) in the affected ear was 29.34 (SD: 8.08) dB-HL. Regarding internal consistency and reliability of the Sp-TFI respectively, Cronbach’s α was 0.83 and the ICC type (2,1) was 1 (CI: 0.99–1). Among the variables studied, we found the following independent predictors had statistically significant effects on THI score: sex (<em>p</em> &lt; 0.01), PTA (<em>p</em> = 0.03), overall Sp-TFI score (<em>p</em> = 0.02) and Sp-TFI SL, R and A subscale scores (<em>p</em> = 0.03, <em>p</em> = 0.03, and <em>p</em> &lt; 0.01, respectively).</p></div><div><h3>Conclusion</h3><p>Based on the internal consistency and reliability results obtained in this study, the cross-culturally adapted Spanish version of the TFI (Sp-TFI) has been validated for use in Spain.</p></div><div><h3>Level of evidence</h3><p>2B: Individual cohort study/low-quality randomized control studies</p></div>","PeriodicalId":7019,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"74 5","pages":"Pages 305-314"},"PeriodicalIF":1.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49778933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Acta otorrinolaringologica espanola
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