Pub Date : 2024-10-01DOI: 10.1016/j.ad.2024.02.035
M. Salleras Redonnet , J. del Pozo Losada , M. Ribera Pibernat
Introduction
Rosacea is a chronic disease negatively impacting the patients’ quality of life and mental health. The Rosacea Quality of Life (RosaQoL) scale could be a useful tool to monitor patients while on therapy vs rosacea, as it measures the impact on quality of life and helps individualize treatment to meet the patients’ needs. RosaQoL is a validated scale that can be completed within a few minutes.
Materials and methods
The original scale was translated and back translated by 2 native translators, with input from an expert committee when necessary. This version was tested on 21 patients to ensure proper understanding. Psychometric characteristics and validity were determined using various measures (sensitivity and specificity via ROC curve and internal consistency via Cronbach's alpha). The correlation between RosaQoL and SF-12 scales was assessed using Pearson correlation coefficients.
Results
A total of 531 participants responded to the scale (481 with rosacea and 50 controls). The scale demonstrated excellent sensitivity and specificity (ROC curve, 0.96; 95%CI, 0.92-0.99) and high internal consistency (Cronbach's alpha, 0.96). RosaQoL correlated with SF-12. A higher score on the RosaQoL scale was associated with worse quality of life in all dimensions of the SF-12 scale.
Conclusions
The Spanish version of the RosaQoL scale exhibits psychometric characteristics, which are similar to the original scale. Also, the RosaQoL scale is useful to assess the quality of life of patients with rosacea.
{"title":"[Translated article] Cross-Cultural Validation of the RosaQoL Scale in Spanish Language","authors":"M. Salleras Redonnet , J. del Pozo Losada , M. Ribera Pibernat","doi":"10.1016/j.ad.2024.02.035","DOIUrl":"10.1016/j.ad.2024.02.035","url":null,"abstract":"<div><h3>Introduction</h3><div>Rosacea is a chronic disease negatively impacting the patients’ quality of life and mental health. The Rosacea Quality of Life (RosaQoL) scale could be a useful tool to monitor patients while on therapy vs rosacea, as it measures the impact on quality of life and helps individualize treatment to meet the patients’ needs. RosaQoL is a validated scale that can be completed within a few minutes.</div></div><div><h3>Materials and methods</h3><div>The original scale was translated and back translated by 2 native translators, with input from an expert committee when necessary. This version was tested on 21 patients to ensure proper understanding. Psychometric characteristics and validity were determined using various measures (sensitivity and specificity via ROC curve and internal consistency via Cronbach's alpha). The correlation between RosaQoL and SF-12 scales was assessed using Pearson correlation coefficients.</div></div><div><h3>Results</h3><div>A total of 531 participants responded to the scale (481 with rosacea and 50 controls). The scale demonstrated excellent sensitivity and specificity (ROC curve, 0.96; 95%<span>C</span>I, 0.92-0.99) and high internal consistency (Cronbach's alpha, 0.96). RosaQoL correlated with SF-12. A higher score on the RosaQoL scale was associated with worse quality of life in all dimensions of the SF-12 scale.</div></div><div><h3>Conclusions</h3><div>The Spanish version of the RosaQoL scale exhibits psychometric characteristics, which are similar to the original scale. Also, the RosaQoL scale is useful to assess the quality of life of patients with rosacea.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2024.09.001
J.C. Pineda , N.R. Alvis-Zakzuk , L. Moyano-Támara , J. Fierro-Lozada , C. Cera-Coll , W. Celorio-Murillo , N.J. Alvis-Zakzuk , J. Zapata-Ospina , J.F. Ruiz-Gómez , J. Zakzuk , N. Alvis-Guzmán , D. Castillo-Molina
Background
Alopecia areata (AA) is an autoimmune disease characterized by non-scaring hair loss and preservation of hair follicles. The information available on disease course, and clinical features of AA is scarce worldwide, and almost nonexistent in Colombia.
Objective
To determine the clinical and sociodemographic characteristics of patients diagnosed with AA who presented to a dermatology consultation in five Colombian cities.
Material and methods
This was a retrospective and multicenter study on data from an ongoing National Registry of Alopecia Areata in Colombia (RENAAC) collected in Bogota, Cali, Cartagena, Barranquilla, and Medellin, Colombia from March 2022 through April 2023. Data was recorded in a standardized form by trained physicians. The variables were expressed as measures of central tendency and dispersion, and absolute and relative frequencies.
Results
A total of 562 patients were included, 59.4% of whom were women, aged between 15 and 49 years (63.9%) with a mean disease course of 1.7 years. The most common finding was multiple plaque (53.2%), the predominant AA subtype was patchy (71.4%), and 29.5% of the patients had a past dermatological history, 18.3% had a past endocrinological history, and 8.9% had a past psychiatric history. The treatments most widely used were steroid injections (76.4%), 5% topical minoxidil (46.4%), followed by high-potency corticosteroids (42.5%).
Study limitations and conclusions
AA was slightly predominant in women. As seen in other populations, this disease had an earlier onset in men vs women. Presentation in pediatric age was uncommon. The previous history of other dermatological diseases was checked in almost one third of the patients. Analysis of the co-presentation of AA with other autoimmune diseases is biased due to excluding patients with systemic erythematous lupus from the study.
背景：斑秃（AA）是一种自身免疫性疾病，其特点是脱发不严重，毛囊可保留。全世界有关 AA 病程和临床特征的资料很少，而在哥伦比亚几乎没有：确定哥伦比亚 5 个城市皮肤科就诊的 AA 患者的临床和社会人口特征：这是一项回顾性多中心研究，研究对象是正在进行的哥伦比亚全国脱发登记处（RENAAC）从2022年3月至2023年4月在哥伦比亚波哥大、卡利、卡塔赫纳、巴兰基亚和麦德林收集的数据。数据由经过培训的医生以标准化的形式获取。变量以中心倾向和离散度、绝对频率和相对频率表示：共纳入 562 名患者，其中 59.4% 为女性，年龄在 15 至 49 岁之间（63.9%），平均病程为 1.7 年。最常见的症状是多发性斑块（53.2%），最主要的 AA 亚型是斑片状（71.4%），29.5%的患者有皮肤病史，18.3%的患者有内分泌病史，8.9%的患者有精神病史。使用最多的治疗方法是类固醇注射（76.4%）、5%的局部米诺地尔（46.4%），其次是高效皮质类固醇激素（42.5%）。研究局限和结论：女性患者中 AA 略占多数。正如在其他人群中看到的那样，这种疾病在男性和女性中发病较早。儿童发病并不常见。近三分之一的患者曾患其他皮肤病。由于研究排除了系统性红斑狼疮患者，因此对AA与其他自身免疫性疾病的共同表现的分析存在偏差。
{"title":"[Artículo traducido] Características clínicas y sociodemográficas de la alopecia areata en 5 ciudades colombianas: un análisis del RENAAC","authors":"J.C. Pineda , N.R. Alvis-Zakzuk , L. Moyano-Támara , J. Fierro-Lozada , C. Cera-Coll , W. Celorio-Murillo , N.J. Alvis-Zakzuk , J. Zapata-Ospina , J.F. Ruiz-Gómez , J. Zakzuk , N. Alvis-Guzmán , D. Castillo-Molina","doi":"10.1016/j.ad.2024.09.001","DOIUrl":"10.1016/j.ad.2024.09.001","url":null,"abstract":"<div><h3>Background</h3><div>Alopecia areata (AA) is an autoimmune disease characterized by non-scaring hair loss and preservation of hair follicles. The information available on disease course, and clinical features of AA is scarce worldwide, and almost nonexistent in Colombia.</div></div><div><h3>Objective</h3><div>To determine the clinical and sociodemographic characteristics of patients diagnosed with AA who presented to a dermatology consultation in five Colombian cities.</div></div><div><h3>Material and methods</h3><div>This was a retrospective and multicenter study on data from an ongoing National Registry of Alopecia Areata in Colombia (RENAAC) collected in Bogota, Cali, Cartagena, Barranquilla, and Medellin, Colombia from March 2022 through April 2023. Data was recorded in a standardized form by trained physicians. The variables were expressed as measures of central tendency and dispersion, and absolute and relative frequencies.</div></div><div><h3>Results</h3><div>A total of 562 patients were included, 59.4% of whom were women, aged between 15 and 49 years (63.9%) with a mean disease course of 1.7 years. The most common finding was multiple plaque (53.2%), the predominant AA subtype was patchy (71.4%), and 29.5% of the patients had a past dermatological history, 18.3% had a past endocrinological history, and 8.9% had a past psychiatric history. The treatments most widely used were steroid injections (76.4%), 5% topical minoxidil (46.4%), followed by high-potency corticosteroids (42.5%).</div></div><div><h3>Study limitations and conclusions</h3><div>AA was slightly predominant in women. As seen in other populations, this disease had an earlier onset in men vs women. Presentation in pediatric age was uncommon. The previous history of other dermatological diseases was checked in almost one third of the patients. Analysis of the co-presentation of AA with other autoimmune diseases is biased due to excluding patients with systemic erythematous lupus from the study.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142144917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2024.02.033
Spanish Autonomous Communities (ACs) are entitled to decide on the prescription requirements of their own territories, which can create inequalities in access to new drugs in the management of psoriasis. The objective of this study was to assess whether the level of restrictions in the access to new drugs for the management psoriasis was associated with the probability of achieving disease control measured using the Minimum Disease Activity (MDA) criteria. Therefore, we combined the results of 2 previous independent, cross-sectional studies: one that described the MDA in psoriasis by AC, and another that evaluated the level of restrictions to drug access by AC. We found that the higher the number of restrictions the lower the chances of achieving the MDA criteria (P=.013). Our results suggest that, in Spain, geographical differences in the access to new drugs may be creating health inequalities across the country.
{"title":"Estudio del impacto de las restricciones en el acceso a fármacos biológicos en psoriasis sobre la actividad mínima de la enfermedad: subanálisis de los proyectos EQUIDAD y AME de la AEDV","authors":"","doi":"10.1016/j.ad.2024.02.033","DOIUrl":"10.1016/j.ad.2024.02.033","url":null,"abstract":"<div><div>Spanish Autonomous Communities (ACs) are entitled to decide on the prescription requirements of their own territories, which can create inequalities in access to new drugs in the management of psoriasis. The objective of this study was to assess whether the level of restrictions in the access to new drugs for the management psoriasis was associated with the probability of achieving disease control measured using the Minimum Disease Activity (MDA) criteria. Therefore, we combined the results of 2 previous independent, cross-sectional studies: one that described the MDA in psoriasis by AC, and another that evaluated the level of restrictions to drug access by AC. We found that the higher the number of restrictions the lower the chances of achieving the MDA criteria (<em>P</em>=.013). Our results suggest that, in Spain, geographical differences in the access to new drugs may be creating health inequalities across the country.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141069722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2024.03.033
Syphilis —the “great simulator” for classical venereologists—is re-emerging in Western countries despite adequate treatment; several contributing factors have been identified, including changes in sexual behaviour, which won’t be the topic of this article though.
In 2021, a total of 6613 new cases of syphilis were reported in Spain, representing an incidence of 13.9 × 100 000 inhabitants (90.5%, men). Rates have increased progressively since 2000.
The clinical presentation of syphilis is heterogeneous. Although chancroid, syphilitic roseola and syphilitic nails are typical lesions, other forms of the disease can be present such as non-ulcerative primary lesions like Follmann balanitis, chancres in the oral cavity, patchy secondary lingual lesions, or enanthema on the palate and uvula, among many others.
Regarding diagnosis, molecular assays such as PCR have been replacing dark-field microscopy in ulcerative lesions while automated treponemal tests (EIA, CLIA) are being used in serological tests, along with classical tests (such as RPR and HAART) for confirmation and follow-up purposes. The interpretation of these tests should be assessed in the epidemiological and clinical context of the patient. HIV serology and STI screening should be requested for anyone with syphilis.
Follow-up of patients under treatment is important to ensure healing and detect reinfection. Serological response to treatment should be assessed with the same non-treponemal test (RPR/VDRL); 3-, 6-, 12-, and 24-month follow-up is a common practice in people living with HIV (PLHIV).
Sexual contacts should be assessed and treated as appropriate.
Screening is advised for pregnant women within the first trimester of pregnancy. Pregnant women with an abortion after week 20 should all be tested for syphilis.
The treatment of choice for all forms of syphilis, including pregnant women and PLHIV, is penicillin. Macrolides are ill-advised because of potential resistance.
{"title":"Documento de expertos de la AEDV para el manejo de la sífilis","authors":"","doi":"10.1016/j.ad.2024.03.033","DOIUrl":"10.1016/j.ad.2024.03.033","url":null,"abstract":"<div><div>Syphilis —the “great simulator” for classical venereologists—is re-emerging in Western countries despite adequate treatment; several contributing factors have been identified, including changes in sexual behaviour, which won’t be the topic of this article though.</div><div>In 2021, a total of 6613 new cases of syphilis were reported in Spain, representing an incidence of 13.9<!--> <!-->×<!--> <!-->100 000 inhabitants (90.5%, men). Rates have increased progressively since 2000.</div><div>The clinical presentation of syphilis is heterogeneous. Although chancroid, syphilitic roseola and syphilitic nails are typical lesions, other forms of the disease can be present such as non-ulcerative primary lesions like Follmann balanitis, chancres in the oral cavity, patchy secondary lingual lesions, or enanthema on the palate and uvula, among many others.</div><div>Regarding diagnosis, molecular assays such as PCR have been replacing dark-field microscopy in ulcerative lesions while automated treponemal tests (EIA, CLIA) are being used in serological tests, along with classical tests (such as RPR and HAART) for confirmation and follow-up purposes. The interpretation of these tests should be assessed in the epidemiological and clinical context of the patient. HIV serology and STI screening should be requested for anyone with syphilis.</div><div>Follow-up of patients under treatment is important to ensure healing and detect reinfection. Serological response to treatment should be assessed with the same non-treponemal test (RPR/VDRL); 3-, 6-, 12-, and 24-month follow-up is a common practice in people living with HIV (PLHIV).</div><div>Sexual contacts should be assessed and treated as appropriate.</div><div>Screening is advised for pregnant women within the first trimester of pregnancy. Pregnant women with an abortion after week 20 should all be tested for syphilis.</div><div>The treatment of choice for all forms of syphilis, including pregnant women and PLHIV, is penicillin. Macrolides are ill-advised because of potential resistance.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140782737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2024.08.001
D. Marín-Piñero, G. Melé-Ninot, M. Quintana-Codina
{"title":"[Translated article] Mondor Disease of the Penis After Sentinel Lymph Node Biopsy in a Patient With Melanoma","authors":"D. Marín-Piñero, G. Melé-Ninot, M. Quintana-Codina","doi":"10.1016/j.ad.2024.08.001","DOIUrl":"10.1016/j.ad.2024.08.001","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2023.04.044
{"title":"Solar Urticaria and Omalizumab: A Retrospective Case–Control Study and Follow-Up","authors":"","doi":"10.1016/j.ad.2023.04.044","DOIUrl":"10.1016/j.ad.2023.04.044","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140058438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2024.04.021
Background
The location of cutaneous melanoma is associated with photoexposure.
Objectives
To retrospectively analyze changes in the location of cutaneous melanoma over the past 30 years.
Patients and methods
All patients treated at our hospital for cutaneous melanoma from 1988 through 2017 were prospectively collected. Data obtained in cases diagnosed from 1988 through June 2006 were compared to those diagnosed from July 2006 through 2017.
Results
A total of 1,937 patients (876 men and 1061 women; median age, 57 years; interquartile range 27) were diagnosed with primary cutaneous melanoma. The location of melanoma was head and neck (470 cases), trunk (745 cases), upper limbs (239 cases), and lower limbs (483 cases). From July 2006 through 2017 we detected an increase in the incidence of head and neck melanomas (19.9% vs 28.6%, p < 0.001). A drop in the incidence of melanomas located in the lower extremities was also seen in women (39.8% vs 30.4%, p < 0.001), and in the trunk men (57.5% vs 47.3%, p = 0.003). In the multivariate analyses, only the decrease in melanomas located in lower extremities in women remained significant.
Conclusion
The increased incidence of head and neck melanomas in both sexes and the decrease in trunk melanomas in men can be attributed to the aging of our population. The reduction in the incidence of melanomas in the lower extremities in women could be associated with changes in photoexposure patterns. Analyzing the factors possibly associated with these changes would contribute to better understanding the pathogenesis of cutaneous melanoma for prevention purposes.
背景：皮肤黑色素瘤的位置与光暴露有关：回顾性分析过去30年中皮肤黑色素瘤位置的变化：前瞻性收集1988年至2017年在本院接受治疗的所有皮肤黑色素瘤患者。将1988年至2006年6月诊断的病例数据与2006年7月至2017年诊断的病例数据进行比较：共有 1937 名患者（男性 876 人，女性 1061 人；中位年龄 57 岁；四分位数间距 27）被确诊为原发性皮肤黑色素瘤。黑色素瘤的发病部位为头颈部（470例）、躯干（745例）、上肢（239例）和下肢（483例）。从2006年7月到2017年，我们发现头颈部黑色素瘤的发病率有所上升（19.9% vs 28.6%，P < 0.001）。女性（39.8% vs 30.4%，p < 0.001）和男性（躯干）（57.5% vs 47.3%，p = 0.003）下肢黑色素瘤的发病率也有所下降。在多变量分析中，只有女性下肢黑色素瘤的减少仍然显著：结论：男女头颈部黑色素瘤发病率的上升和男性躯干黑色素瘤发病率的下降可归因于我国人口的老龄化。女性下肢黑色素瘤发病率的降低可能与光照模式的变化有关。分析可能与这些变化有关的因素将有助于更好地了解皮肤黑色素瘤的发病机制，从而达到预防目的。
{"title":"Cambios en la localización del melanoma cutáneo en los últimos 30 años. Estudio observacional retrospectivo","authors":"","doi":"10.1016/j.ad.2024.04.021","DOIUrl":"10.1016/j.ad.2024.04.021","url":null,"abstract":"<div><h3>Background</h3><div>The location of cutaneous melanoma is associated with photoexposure.</div></div><div><h3>Objectives</h3><div>To retrospectively analyze changes in the location of cutaneous melanoma over the past 30 years.</div></div><div><h3>Patients and methods</h3><div>All patients treated at our hospital for cutaneous melanoma from 1988 through 2017 were prospectively collected. Data obtained in cases diagnosed from 1988 through June 2006 were compared to those diagnosed from July 2006 through 2017.</div></div><div><h3>Results</h3><div>A total of 1,937 patients (876 men and 1061 women; median age, 57 years; interquartile range 27) were diagnosed with primary cutaneous melanoma. The location of melanoma was head and neck (470 cases), trunk (745 cases), upper limbs (239 cases), and lower limbs (483 cases). From July 2006 through 2017 we detected an increase in the incidence of head and neck melanomas (19.9% vs 28.6%, p <<!--> <!-->0.001). A drop in the incidence of melanomas located in the lower extremities was also seen in women (39.8% vs 30.4%, p <<!--> <!-->0.001), and in the trunk men (57.5% vs 47.3%, p<!--> <!-->=<!--> <!-->0.003). In the multivariate analyses, only the decrease in melanomas located in lower extremities in women remained significant.</div></div><div><h3>Conclusion</h3><div>The increased incidence of head and neck melanomas in both sexes and the decrease in trunk melanomas in men can be attributed to the aging of our population. The reduction in the incidence of melanomas in the lower extremities in women could be associated with changes in photoexposure patterns. Analyzing the factors possibly associated with these changes would contribute to better understanding the pathogenesis of cutaneous melanoma for prevention purposes.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141069614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2024.04.028
J.R. Ferreres , J. Molinero Caturla , J. Sánchez Sánchez , M. Gamissans , A. Vinyals , J. Bermejo , R.M. Penín , À. Fabra , J. Marcoval
Background
The location of cutaneous melanoma is associated with photoexposure.
Objectives
To retrospectively analyze changes in the location of cutaneous melanoma over the past 30 years.
Patients and methods
All patients treated at our hospital for cutaneous melanoma from 1988 through 2017 were prospectively collected. Data obtained in cases diagnosed from 1988 through June 2006 were compared to those diagnosed from July 2006 through 2017.
Results
A total of 1,937 patients (876 men and 1061 women; median age, 57 years; interquartile range 27) were diagnosed with primary cutaneous melanoma. The location of melanoma was head and neck (470 cases), trunk (745 cases), upper limbs (239 cases), and lower limbs (483 cases). From July 2006 through 2017 we detected an increase in the incidence of head and neck melanomas (19.9% vs 28.6%, p < 0.001). A drop in the incidence of melanomas located in the lower extremities was also seen in women (39.8% vs 30.4%, p < 0.001), and in the trunk men (57.5% vs 47.3%, p = 0.003). In the multivariate analyses, only the decrease in melanomas located in lower extremities in women remained significant.
Conclusion
The increased incidence of head and neck melanomas in both sexes and the decrease in trunk melanomas in men can be attributed to the aging of our population. The reduction in the incidence of melanomas in the lower extremities in women could be associated with changes in photoexposure patterns. Analyzing the factors possibly associated with these changes would contribute to better understanding the pathogenesis of cutaneous melanoma for prevention purposes.
背景：皮肤黑色素瘤的位置与光暴露有关：回顾性分析过去30年中皮肤黑色素瘤位置的变化：前瞻性收集1988年至2017年在本院接受治疗的所有皮肤黑色素瘤患者。将1988年至2006年6月诊断的病例数据与2006年7月至2017年诊断的病例数据进行比较：共有 1937 名患者（男性 876 人，女性 1061 人；中位年龄 57 岁；四分位数间距 27）被确诊为原发性皮肤黑色素瘤。黑色素瘤的发病部位为头颈部（470例）、躯干（745例）、上肢（239例）和下肢（483例）。从2006年7月到2017年，我们发现头颈部黑色素瘤的发病率有所上升（19.9% vs 28.6%，P < 0.001）。女性（39.8% vs 30.4%，p < 0.001）和男性（躯干）（57.5% vs 47.3%，p = 0.003）下肢黑色素瘤的发病率也有所下降。在多变量分析中，只有女性下肢黑色素瘤的减少仍然显著：结论：男女头颈部黑色素瘤发病率的上升和男性躯干黑色素瘤发病率的下降可归因于我国人口的老龄化。女性下肢黑色素瘤发病率的降低可能与光照模式的变化有关。分析可能与这些变化有关的因素将有助于更好地了解皮肤黑色素瘤的发病机制，从而达到预防目的。
{"title":"[Translated article] Changes in the Location of Cutaneous Melanoma Over the Past 30 Years. A Retrospective Observational Study","authors":"J.R. Ferreres , J. Molinero Caturla , J. Sánchez Sánchez , M. Gamissans , A. Vinyals , J. Bermejo , R.M. Penín , À. Fabra , J. Marcoval","doi":"10.1016/j.ad.2024.04.028","DOIUrl":"10.1016/j.ad.2024.04.028","url":null,"abstract":"<div><h3>Background</h3><div>The location of cutaneous melanoma is associated with photoexposure.</div></div><div><h3>Objectives</h3><div>To retrospectively analyze changes in the location of cutaneous melanoma over the past 30 years.</div></div><div><h3>Patients and methods</h3><div>All patients treated at our hospital for cutaneous melanoma from 1988 through 2017 were prospectively collected. Data obtained in cases diagnosed from 1988 through June 2006 were compared to those diagnosed from July 2006 through 2017.</div></div><div><h3>Results</h3><div>A total of 1,937 patients (876 men and 1061 women; median age, 57 years; interquartile range 27) were diagnosed with primary cutaneous melanoma. The location of melanoma was head and neck (470 cases), trunk (745 cases), upper limbs (239 cases), and lower limbs (483 cases). From July 2006 through 2017 we detected an increase in the incidence of head and neck melanomas (19.9% vs 28.6%, p <<!--> <!-->0.001). A drop in the incidence of melanomas located in the lower extremities was also seen in women (39.8% vs 30.4%, p <<!--> <!-->0.001), and in the trunk men (57.5% vs 47.3%, p<!--> <!-->=<!--> <!-->0.003). In the multivariate analyses, only the decrease in melanomas located in lower extremities in women remained significant.</div></div><div><h3>Conclusion</h3><div>The increased incidence of head and neck melanomas in both sexes and the decrease in trunk melanomas in men can be attributed to the aging of our population. The reduction in the incidence of melanomas in the lower extremities in women could be associated with changes in photoexposure patterns. Analyzing the factors possibly associated with these changes would contribute to better understanding the pathogenesis of cutaneous melanoma for prevention purposes.</div></div>","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141900590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.ad.2023.05.042
{"title":"Uso de la luz ultravioleta LED 365 nm en el diagnóstico de escabiosis","authors":"","doi":"10.1016/j.ad.2023.05.042","DOIUrl":"10.1016/j.ad.2023.05.042","url":null,"abstract":"","PeriodicalId":7173,"journal":{"name":"Actas dermo-sifiliograficas","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140329518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号