Biomaterial investigations in dentistry最新文献

Objective: To investigate the properties (tensile strength, roughness, abrasiveness) of different dental flosses and how these properties relate to subjective preference for floss by users.

Materials and method: Four flosses of differing compositions were selected (polytetrafluoroethylene (PTFE), nylon, silk, and ultra-high-molecular-weight polyethylene (UHMWPE)). Tensile strength (TS) was measured utilising a universal testing machine (total n = 40). Surface roughness (Ra) was measured on 3D reconstructed models of scanning electron microscope and abrasiveness was measured through block-on-ring tests against human enamel. Subjective preference for floss was measured by asking a sample of 16 individuals to use each floss for an 8-day period using a split-mouth design.

Results: The highest TS was found in UHMWPE floss (194.18$\pm$24.61 MPa) while the lowest TS was found in PTFE floss (11.78$\pm$0.77 MPa). Silk floss had the highest Ra (0.304$\pm$0.025 µm) while PTFE floss had the lowest (0.048$\pm$0.003 µm). In-vitro abrasion testing of the flosses identified no significant differences between the flosses in causing wear on tooth enamel. Subjective ratings of flosses indicated PTFE floss to be most preferred and nylon floss to be least preferred.

Conclusion: There was a difference in subjective preference between dental flosses composed of different materials. The PTFE floss was the overall most preferred while the nylon floss was the least preferred. There was also an association between the mechanical properties and preference for their usage, with PTFE floss being the most preferred but having the lowest surface roughness and tensile strength.

Clinical relevance: This study compared a wide range of mechanical properties and subject preferences of commercially available dental floss. The results of this study can provide guidance for the recommendation of dental floss for oral hygiene routines.

Background: The purpose of this in vitro study was to evaluate the effect of different adhesion primers on the repair bond strength of bulk-fill resin composite and short-term hydrolytic stability of the repair interface before and after accelerated aging. In addition, direction of debonding stress was examined.

Materials and methods: Bulk-fill substrates were aged in water for 14 days at 37 °C. Smooth resin composite surfaces were prepared for the substrates with a superfine grinding paper (FEPA #500, #1200, #2000). Test specimens were produced by attaching bulk-fill composite to the substrate surfaces, using three different primer/bonding systems. Specimens were aged 24 h at 37 °C in water, or thermal cycled (5-55 °C/5,000 cycles). Subsequently, shear bond strength and micro-tensile bond strength were evaluated. In total there were 60 specimens for the shear bond strength and 60 specimens for the micro-tensile bond strength measurements (30 stored in water 24 h, 30 thermal cycled, n = 10 in each primer/bonding mode).

Results: The mean shear bond strength was 9.1-13.1 MPa after 24 h water storage and 6.9-10.7 MPa after thermal cycling. The mean micro-tensile bond strength was 28.7-45.8 MPa after 24 h water storage and 22.7-37.9 MPa after thermal cycling.

Conclusion: The Ceramic primer (silane containing) seems to perform better than the three-step etch and rinse adhesive or the Composite primer. Shear-type stress had an adverse effect on the repair bond strength of bulk-fill resin composites.

Flowable bulk-fill resin-based composites (BF-RBCs) represent a new and interesting alternative for the bulk-fill restorative techniques in the posterior region. However, they comprise a heterogeneous group of materials, with important differences in composition and design. Therefore, the aim of the present systematic review was to compare the main properties of flowable BF-RBCs, including their composition, degree of monomer conversion (DC), polymerization shrinkage and shrinkage stress, as well as flexural strength. The search was conducted following PRISMA guidelines in the Medline (PubMed), Scopus and Web of Science databases. In vitro articles reporting on the DC, polymerization shrinkage/shrinkage stress, and flexural strength of flowable BF-RBCs strength were included. The QUIN risk-of-bias (RoB) tool was used for assessing the study quality. From initially 684 found articles, 53 were included. Values for DC ranged between 19.41 and 93.71%, whereas polymerization shrinkage varied between 1.26 and 10.45%. Polymerization shrinkage stresses reported by most studies ranged between 2 and 3 MPa. Flexural strength was above 80 MPa for most materials. A moderate RoB was observed in most studies. Flowable BF-RBCs meet the requirements to be indicated for bulk fill restoration technique in the posterior region. However, important variations among composition and properties hinder extrapolation of the results to materials different from those reported here. Clinical studies are urgently required to assess their performance under a real working scenario.

Dental resin composites (DRCs) have become the first choice among different restorative materials for direct anterior and posterior restorations in the clinic. Though the properties of DRCs have been improved greatly in recent years, they still have several shortcomings, such as volumetric shrinkage and shrinkage stress, biofilm development, lack of radio-opacity for some specific DRCs, and estrogenicity, which need to be overcome. The resin matrix, composed of different monomers, constitutes the continuous phase and determine the performance of DRCs. Thus, the chemical structure of the monomers plays an important role in modifying the properties of DRCs. Numerous researchers have taken to design and develop novel monomers with specific functions for the purpose of fulfilling the needs in dentistry. In this review, the development of monomers in DRCs were highlighted, especially focusing on strategies aimed at reducing volumetric shrinkage and shrinkage stress, endowing bacteriocidal and antibacterial adhesion activities as well as protein-repelling activity, increasing radio-opacity, and replacing Bis-GMA. The influences of these novel monomers on the properties of DRCs were also discussed.

Objective: To compare the cumulative impact of sequential wear on mechanical properties and appearance of a composite resin (CR), Filtek Z250^®, a glass ionomer GI, Fuji IX GP^®, and a glass hybrid (GH), Equia Forte^®.

Material and methods: Six equally sized specimens of each material were subjected to wear tests, i.e., simulation of brushing, chewing and acidic liquid exposure, mimicking at least 6 months of clinical exposure. Surface roughness, hardness, substance loss and degree of shade lightness were determined.

Results: Following wear tests, significant increase in surface roughness and decrease in hardness values were observed for all materials (p < .05). Significantly larger substance loss was found in Equia Forte^® specimens compared to Filtek Z250^® (p < .05), while that of Fuji IX^® exceeded the measurement capacity of the instrument. Opposite to the two other materials, the shade of Filtek Z250^® became darker.

Conclusions: Sequential wear exposure mimicking abrasion, erosion and attrition to products representing CR, GI and GH, caused weakening and change in appearance of the materials. The composite resin was the most mechanically resistant to the sequential wear.

For individuals with very high to extremely high caries activity and poor control of daily oral hygiene, a simple treatment for arresting their caries activity is necessary. Silver Diamine Fluoride (SDF) has become increasingly common for this purpose due to its efficacy and ease of application. To avoid or reduce tooth discoloration after SDF treatment potassium iodide (KI) may be applied. However, the release of silver from SDF-treated tooth surfaces may be of concern. Thus, the aim of the present study was to quantify the amount of silver leached in both a short- and long-term perspective. In this in vitro experiment we measured the cumulative release of silver from SDF-treated dentin surfaces with and without imminent application of KI, and with and without phosphoric acid etching as pre-treatment, after 24 h and weekly for four weeks. The release of silver was highest after 24 h for all treatment groups, with a significant drop after this point. When etching was not used, the use of KI did not affect the release of silver. However, when etching was used, there was a significantly lower silver release when KI was also used compared to when KI was not used. This effect was largest for the first two weeks, after which the difference was smaller as all groups released low amounts of silver.

In head and neck cancer patients receiving dental implants prior to radiotherapy, backscatter from titanium increases the radiation dose close to the surface, and may affect the osseointegration. The dose-dependent effects of ionizing radiation on human osteoblasts (hOBs) were investigated. The hOBs were seeded on machined titanium, moderately rough fluoride-modified titanium, and tissue culture polystyrene, and cultured in growth- or osteoblastic differentiation medium (DM). The hOBs were exposed to ionizing γ-irradiation in single doses of 2, 6 or 10 Gy. Twenty-one days post-irradiation, cell nuclei and collagen production were quantified. Cytotoxicity and indicators of differentiation were measured and compared to unirradiated controls. Radiation with backscatter from titanium significantly reduced the number of hOBs but increased the alkaline phosphatase activity in both types of medium when adjusted to the relative cell number on day 21. Irradiated hOBs on the TiF-surface produced similar amounts of collagen as unirradiated controls when cultured in DM. The majority of osteogenic biomarkers significantly increased on day 21 when the hOBs had been exposed to 10 Gy, while the opposite or no effect was observed after lower doses. High doses reinforced with backscatter from titanium resulted in smaller but seemingly more differentiated subpopulations of osteoblasts.