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Comparative efficacy of lifestyle intervention strategies targeting weight outcomes in people with psychosis: a systematic review and network meta-analysis. 针对精神病患者体重结果的生活方式干预策略的比较疗效:系统回顾和网络荟萃分析。
Pub Date : 2019-09-01 DOI: 10.11124/JBISRIR-2017-003943
Doreen Mucheru, M. Hanlon, M. McEvoy, A. Thakkinstian, L. MacDonald-Wicks
OBJECTIVESThe objective of this review was to pool and rank the efficacy of lifestyle intervention strategies targeting weight, body mass index, waist circumference and waist-to-hip ratio in people with psychosis by comparing the effect size of these weight outcomes. Secondary to this, the objective was to stratify the lifestyle interventions according to their inclusion of dietary information that adheres to Australian Dietary Guidelines.INTRODUCTIONPeople living with psychosis have a significantly increased risk of all-cause mortality, with cardiovascular disease a considerable contributor to this risk. Controlling lifestyle risk factors, which include smoking, poor diet and inadequate physical activity, leads to significant weight reduction and decreases cardiovascular disease risk. Previous reviews on this topic have not clearly identified essential components of lifestyle interventions in people with psychosis, mainly due to statistical limitations of analyses. This review employed the network meta-analysis, which compares more than two groups of interventions and ranks them according to efficacy, thus providing a global estimate of effect. Additionally, available reviews have not assessed compliance of dietary information offered in lifestyle interventions to established guidelines.INCLUSION CRITERIAThis review considered randomized controlled studies that delivered lifestyle interventions to community-dwelling adults with psychotic disorders. Outcomes of interest were weight, body mass index, waist circumference and waist-to-hip ratio.METHODSThe Cochrane Library, MEDLINE/PreMEDLINE, Embase, CINAHL, Scopus and PsycINFO were searched for studies published in English from 1985 to June 2018. Data were qualitatively summarized, during which lifestyle intervention subgroups were created (based on key similarities) and then compared in direct meta-analyses and network meta-analyses. Assessments of study adherence to Australian Dietary Guidelines was conducted in a narrative format.RESULTSThirty-two randomized control studies were included, and the overall quality of these studies ranged from what appeared to be low to moderate. Lifestyle intervention studies contained both a dietary and physical activity component, with the exception of two studies that focused solely on physical activity. Delivery of dietary and physical activity information was mainly through education; however, some studies provided additional structure to the intervention by offering tailored advice or helping participants to set goals, and providing regular review of progress for diet, physical activity or both. Results from network-meta-analyses showed that only studies with a structured approach for both diet and physical activity demonstrated significant decreases in weight (effect size = -4.12, 95% confidence interval = -7.772 to -2.760, P = 0.000) and body mass index (effect size = -2.94, 95% confidence interval = -1.78 to -0.357, P = 0.003). Waist circ
目的:本综述的目的是通过比较这些体重结局的效应大小,对针对精神病患者体重、体重指数、腰围和腰臀比的生活方式干预策略的疗效进行汇总和排名。其次,研究的目标是根据饮食信息对生活方式干预进行分层,这些信息符合澳大利亚饮食指南。精神病患者的全因死亡风险显著增加,心血管疾病是造成这一风险的重要因素。控制生活方式的风险因素,包括吸烟、不良饮食和身体活动不足,可以显著减轻体重,降低心血管疾病的风险。先前关于这一主题的综述并没有明确确定精神病患者生活方式干预的基本组成部分,主要是由于分析的统计局限性。本综述采用网络荟萃分析,对两组以上的干预措施进行比较,并根据疗效对其进行排名,从而提供对效果的总体估计。此外,现有的综述尚未评估生活方式干预中提供的饮食信息是否符合既定指南。纳入标准:本综述纳入了对社区居住的成年精神病患者进行生活方式干预的随机对照研究。感兴趣的结果是体重、体重指数、腰围和腰臀比。方法检索1985年至2018年6月Cochrane Library、MEDLINE/PreMEDLINE、Embase、CINAHL、Scopus和PsycINFO等英文文献。对数据进行定性总结,在此期间(基于关键相似性)创建生活方式干预亚组,然后在直接荟萃分析和网络荟萃分析中进行比较。对澳大利亚膳食指南依从性的评估以叙述形式进行。结果纳入32项随机对照研究,这些研究的总体质量从低到中等不等。生活方式干预研究包括饮食和身体活动两部分,只有两项研究只关注身体活动。饮食和体育活动信息主要通过教育传递;然而,一些研究通过提供量身定制的建议或帮助参与者设定目标,并定期回顾饮食、体育活动或两者的进展,为干预提供了额外的结构。网络荟萃分析的结果显示,只有对饮食和身体活动采用结构化方法的研究显示体重(效应值= -4.12,95%置信区间= -7.772至-2.760,P = 0.000)和体重指数(效应值= -2.94,95%置信区间= -1.78至-0.357,P = 0.003)显著降低。腰围亚组比较主要由单个研究组成;因此,研究结果是不确定的。研究中提供的膳食信息一般符合澳大利亚膳食指南;然而,没有一项研究符合所有的指导方针。结论结合饮食和身体活动成分的生活方式干预导致精神病患者体重(4.1 kg)和体重指数(2.9点)的最大下降。这两个组成部分的重要干预策略是通过量身定制的建议或目标设定来实现个性化教育,并进行相应的进展审查。纳入研究的饮食信息似乎符合澳大利亚饮食指南。然而,这些发现被偏倚风险增加、复杂和多组分研究设计以及研究方法报告缺乏明确性所削弱。
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引用次数: 7
Fluid balance monitoring in congestive heart failure patients in hospital: a best practice implementation project. 医院充血性心力衰竭患者体液平衡监测:最佳实践实施项目。
Pub Date : 2019-08-28 DOI: 10.11124/JBISRIR-2017-004021
Shu-Hua Yang, P. Mu, Hsiu-ling Wu, Marianne Curia
OBJECTIVESThis aim of this project was to promote best practice in fluid balance monitoring in congestive heart failure patients.INTRODUCTIONFluid overload or pulmonary/vascular congestion is a common clinical feature of patients with heart failure and is associated with adverse outcomes. Maintaining records of patients' fluid intake and output (I&O) has long been considered an important aspect of nursing care to assess hydration status. In clinical practice, a prevalence of incongruence between I&O results and clinical signs and symptoms has been noted. We postulate that this incongruence may be due to an inaccurate or non-comprehensive collection of fluid I&O and/or the patient's and their families' inadequate recognition of the importance of I&O recording.METHODSThis implementation project was conducted in a cardiology ward of a medical hospital using the Joanna Briggs Institute Practical Application of Clinical Evidence System. Three audit criteria were utilized to represent best practice recommendations for fluid balance monitoring. A pre-implementation audit was conducted, followed by development of multiple interventions identified from a Getting Research into Practice analysis. Two post-implementation audits were conducted to determine the change in practice.RESULTSThe post-implementation audit data demonstrated significantly improved outcomes across the measured best practice criteria. Specifically, improvement in compliance was noted in: i) fluid balance charts being utilized in conjunction with physical assessment and electrolyte monitoring to assess the hydration status of a patient (from 58% to 100% compliance); ii) patient involvement in more accurate documentation (from 42% to 75% compliance); and iii) staff education in fluid balance monitoring and documentation (from 53% to 100% compliance).CONCLUSIONFluid record omission was reduced at the completion of the project secondary to an increased awareness of the fluid record omission standards among patients as well as physical assessment and fluid overload correlation among the nursing staff in the unit. The findings demonstrate how audits can be utilized to promote best practice in healthcare. Additionally, the data indicates that focused education and the provision of relevant resources can have an immediate and positive impact on clinical practice.
目的:促进充血性心力衰竭患者体液平衡监测的最佳实践。液体超载或肺/血管充血是心力衰竭患者的常见临床特征,并与不良结局相关。长期以来,保持患者液体摄入和排出(I&O)的记录一直被认为是评估水合状态的护理的一个重要方面。在临床实践中,已注意到I&O结果与临床体征和症状之间普遍存在不一致。我们假设这种不一致可能是由于不准确或不全面的液体I&O收集和/或患者及其家属对I&O记录的重要性认识不足。方法本实施项目在某医院心内科病房采用乔安娜·布里格斯研究所临床证据实际应用系统进行。采用三项审计标准作为流体平衡监测的最佳做法建议。进行了实施前审计,随后制定了从研究转化为实践分析中确定的多种干预措施。进行了两次执行后审计,以确定做法的变化。结果实施后的审计数据显示,在衡量的最佳实践标准中,结果显著改善。具体而言,依从性的改善体现在:i)体液平衡图与身体评估和电解质监测结合使用,以评估患者的水合状态(依从性从58%提高到100%);Ii)患者参与更准确的记录(从42%到75%的依从性);iii)对员工进行流体平衡监测和文件编制方面的教育(合规率从53%提高到100%)。结论在项目完成后,由于患者对漏液记录标准的认识提高,以及护理人员对身体评估和体液超载的相关性的认识提高,漏液记录减少。研究结果表明如何利用审计来促进医疗保健领域的最佳实践。此外,数据表明,重点教育和提供相关资源可以对临床实践产生直接和积极的影响。
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引用次数: 6
Assessment and management of pain during dressing change in patients with diabetic foot ulcers: a best practice implementation project. 糖尿病足溃疡患者换药期间疼痛的评估和管理:最佳实践实施项目。
Pub Date : 2019-08-28 DOI: 10.11124/JBISRIR-2018-004039
Ying Ren, Xiang-rong Luo, Cuihua Xie, Ping Zhang, M. Meng, Huijuan Song
INTRODUCTIONPain caused by dressing change has adverse effects on patients with a diabetic foot ulcer, including sleep disturbances, immobility, depression and anxiety. It is crucial that healthcare professionals use a standardized tool to assess and document pain during dressing change and then use this information to inform strategies to alleviate the pain.OBJECTIVESThe aim of this project was to implement evidence-based practice in assessment and management of pain during dressing change among patients with diabetic foot ulcers in an endocrinology unit in a tertiary hospital.METHODSThe JBI Practical Application of Clinical Evidence System (JBI PACES) and Getting Research into Practice (GRiP) audit and feedback tool were used for auditing clinical practice and translating evidence into practice. A baseline audit was performed to assess compliance with six criteria, followed by the implementation of evidence-based interventions to improve compliance. The follow-up audit using the same audit criteria was conducted to assess the effect of targeted strategies on compliance with best practice.RESULTSThe baseline audit revealed that compliance with evidence-based practice was low, with only one of the six audit criteria achieving a compliance rate above 60%. After brainstorming and synthesizing the literature, the project team identified barriers and strategies for implementing best practice. The follow-up audit showed improvements in compliance across all six criteria, although there was only a small improvement in one of the criteria. The compliance rate of the other five criteria improved to greater than 67%.CONCLUSIONA best practice implementation project that involved standardizing pain assessment and management, and delivering education materials to nursing staff and patients was completed using JBI PACES and GRiP. The project improved nurses' compliance with best practice. Nurses attach importance to relieving patients' pain when they accept wound care, while patients with a diabetic foot ulcer gain access to high-quality wound care. Future studies will be conducted to address new barriers that emerged during the follow-up audit.
换药引起的疼痛对糖尿病足溃疡患者有不良影响,包括睡眠障碍、行动不便、抑郁和焦虑。至关重要的是,医疗保健专业人员使用标准化的工具来评估和记录换药过程中的疼痛,然后使用这些信息来告知减轻疼痛的策略。目的:在某三级医院内分泌科对糖尿病足溃疡患者换药时疼痛的评估和管理进行循证实践。方法采用JBI临床证据系统的实际应用(JBI PACES)和将研究转化为实践(GRiP)审计和反馈工具对临床实践进行审计,并将证据转化为实践。进行基线审计以评估是否符合六项标准,随后实施循证干预措施以提高依从性。使用相同的审计标准进行了后续审计,以评估目标战略对遵守最佳做法的影响。结果基线审计显示,对循证实践的符合率较低,六个审计标准中只有一个达到了60%以上的符合率。在头脑风暴和综合文献之后,项目团队确定了实现最佳实践的障碍和策略。后续审计显示,所有六个标准的遵守情况都有所改善,尽管其中一个标准只有很小的改善。其他5项指标的符合率均提高到67%以上。结论采用JBI PACES和GRiP完成了规范化疼痛评估和管理、向护理人员和患者发放教育材料的最佳实践实施项目。该项目提高了护士对最佳实践的依从性。护士在接受伤口护理时重视减轻患者的疼痛,糖尿病足溃疡患者获得高质量的伤口护理。今后将进行研究,以解决后续审计期间出现的新障碍。
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引用次数: 3
Effects of flavonoid rich fruits on hypertension in adults: a systematic review. 富含类黄酮的水果对成人高血压的影响:一项系统综述。
Pub Date : 2019-08-23 DOI: 10.11124/JBISRIR-D-19-00050
L. Ellwood, Gizemnur Torun, Z. Bahar, R. Fernandez
OBJECTIVEThe objective of this systematic review was to synthesize the best available research evidence on the effectiveness of flavonoid rich fruits in the treatment of hypertension.INTRODUCTIONHypertension is a serious public health concern as it contributes to a significant burden of disease, attributable for millions of deaths globally. Complementary therapies including flavonoids have generated interest in assisting the treatment of hypertension. Flavonoids are a type of polyphenol abundant in fruits and a growing body of evidence suggests antihypertensive effects of the flavonoids due to its antioxidant properties. To date, no systematic review has been performed to collate the evidence on the effects of flavonoid rich fruits on hypertension in adults.INCLUSION CRITERIAThis systematic review included only randomized controlled trials (RCTs) that compared the administration of any type of flavonoid rich fruit or equivalent supplement with a placebo or other intervention in adults with hypertension. Trials that measured blood pressure using objective outcome measures such as a manual mercury sphygmomanometer were included. Studies that did not specify the flavonoid component of the fruit or fruit supplement were excluded in the review. Secondary outcomes, including change in weight, blood glucose level, triglycerides and total blood cholesterol levels were also assessed.METHODSA three-step search was undertaken, including a comprehensive search of the MEDLINE, Embase, Cochrane Trials (CENTRAL) and CINAHL databases, in September 2018. We also searched Dissertation Abstracts International, ProQuest Dissertations and Theses, MedNar and ClinicalTrials.gov to identify unpublished studies. The title and abstracts of the studies were reviewed by two independent reviewers against the inclusion/exclusion criteria. The methodological quality of the potential studies for inclusion were assessed using the critical appraisal checklist for randomized controlled trials as recommended by the Joanna Briggs Institute. Data were pooled in a statistical meta-analysis model. Subgroup-analysis according to type of intervention and length of intervention period was performed. Where statistical pooling was not possible, the findings have been presented in a narrative form.RESULTSFifteen randomized controlled trials involving 572 participants were included in the review. The subclasses of flavonoids assessed included: anthocyanins, naringin, narirutin and flavan-3-ols. The overall methodological quality of the trials was high. Six trials investigated the effect of the flavonoid intervention on blood pressure within four weeks. Meta-analysis of five of the trials demonstrated evidence of no effect of flavonoids on systolic or diastolic blood pressure when compared to placebo (systolic mean difference = -1.02, 95% CI -3.12, 1.07; p = 0.34, I = 0%; diastolic mean difference = -0.90, 95% CI -2.10, 0.31; p = 0.15, I = 0%). Similarly, pooled results from t
目的对富含类黄酮的水果治疗高血压的有效性进行系统综述。高血压是一个严重的公共卫生问题,因为它是造成全球数百万人死亡的重要疾病负担。包括类黄酮在内的辅助疗法已引起人们对协助治疗高血压的兴趣。黄酮类化合物是水果中富含的一种多酚,越来越多的证据表明,由于其抗氧化特性,黄酮类化合物具有抗高血压作用。到目前为止,还没有系统的综述来整理富含类黄酮的水果对成人高血压的影响。纳入标准:本系统综述仅纳入随机对照试验(RCTs),比较任何类型的富含类黄酮的水果或等效补充剂与安慰剂或其他干预措施对高血压成人的影响。使用客观结果测量方法(如手动水银血压计)测量血压的试验被纳入研究。没有明确指明水果或水果补充剂中黄酮类成分的研究被排除在综述之外。次要结果,包括体重、血糖水平、甘油三酯和总血胆固醇水平的变化也被评估。方法于2018年9月对MEDLINE、Embase、Cochrane Trials (CENTRAL)和CINAHL数据库进行三步检索。我们还检索了Dissertation Abstracts International、ProQuest Dissertation and Theses、MedNar和ClinicalTrials.gov,以确定未发表的研究。研究的标题和摘要由两名独立的审稿人根据纳入/排除标准进行审查。采用乔安娜布里格斯研究所推荐的随机对照试验关键评估清单对纳入的潜在研究的方法学质量进行评估。数据汇总在统计荟萃分析模型中。按干预类型和干预时间长短进行亚组分析。在无法进行统计汇总的情况下,调查结果以叙述形式提出。结果纳入15项随机对照试验,572名受试者。评估的黄酮类化合物亚类包括:花青素、柚皮苷、水杨柳素和黄烷-3-醇。试验的总体方法学质量很高。六项试验调查了类黄酮干预在四周内对血压的影响。五项试验的荟萃分析显示,与安慰剂相比,黄酮类化合物对收缩压或舒张压没有影响(收缩压平均差= -1.02,95% CI -3.12, 1.07;p = 0.34, I = 0%;舒张平均差= -0.90,95% CI -2.10, 0.31;p = 0.15, I = 0%)。同样,24小时内两次给药干预的两项交叉随机对照试验的汇总结果显示,舒张压的降低没有效果(p = 0.38),但收缩压的降低有证据(p = 0)。六项评估黄酮类干预后血压的试验在超过四周的随访中显示,对两种收缩压均无影响(平均差异= -0.95,95%CI -3.58, 1.68;p = 0.478, I = 0%)或舒张压(平均差值= 0.86,95%CI -1.11, 2.82;p = 0.393, I = 0%)。结论:本系统综述的结果来自小样本量的单中心试验,因此应谨慎解读。鉴于本综述提供的结果,有证据表明黄酮类化合物对收缩压和舒张压没有影响。需要进一步使用基于功率计算的样本量进行可靠的随机对照试验,为使用富含类黄酮的水果治疗高血压提供证据。
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引用次数: 14
Effectiveness and harms of pharmacological interventions for the treatment of delirium in adults in intensive care units after cardiac surgery: a systematic review. 药物干预治疗心脏手术后重症监护病房成人谵妄的有效性和危害:一项系统综述。
Pub Date : 2019-08-22 DOI: 10.11124/JBISRIR-D-18-00010
Vivienne Leigh, Cindy Stern, Rosalind M. Elliott, C. Tufanaru
OBJECTIVEThe objective of this review was to synthesize the best available evidence on the effectiveness and harms of pharmacological interventions for the treatment of delirium in adult patients in the intensive care unit (ICU) after cardiac surgery.INTRODUCTIONPatients who undergo cardiac surgery are at high risk of delirium (incidence: 50-90%). Delirium has deleterious effects, increasing the risk of death and adversely affecting recovery. Clinical interventional trials have been conducted to prevent and treat postoperative delirium pharmacologically including antipsychotics and sedatives. These trials have provided some evidence about efficacy and influenced clinical decision making. However, much reporting is incomplete and provides biased assessments of efficacy; benefits are emphasized while harms are inadequately reported.INCLUSION CRITERIAParticipants were ≥ 16 years, any sex or ethnicity, who were treated postoperatively in a cardiothoracic ICU following cardiac surgery and were identified as having delirium. Any pharmacological intervention for the treatment of delirium was included, regardless of drug classification, dosage, intensity or frequency of administration. Outcomes of interest of this review were: mortality, duration and severity of delirium, use of physical restraints, quality of life, family members' satisfaction with delirium management, duration/severity of the aggressive episode, associated falls, severity of accidental self-harm, pharmacological harms, harms related to over-sedation, ICU length of stay, hospital length of stay (post ICU), total hospital length of stay, need for additional intervention medication and need for rescue medication. Randomized controlled trials were considered first and in their absence, non-randomized controlled trials and quasi-experimental would have been considered, followed by analytical observational studies.METHODSA search was conducted in PubMed, Embase, CINAHL, Web of Science, Cochrane Central Register of Controlled Trials, Scopus, Epistemonikos, Australian New Zealand Clinical Trials Registry, ClinicalTrials.gov, Clinical Trials in New Zealand, and ProQuest Dissertations and Theses to locate both published and unpublished studies. There was no date limit for the search. A hand search for primary studies published between January 1, 2012 and November 17, 2018 in relevant journals was also conducted. Only studies published in English were considered for inclusion. Two reviewers independently assessed the methodological quality using standardized critical appraisal instruments from JBI and McMaster University. Quantitative data were extracted using the standardized JBI data extraction tool. A meta-analysis was not performed, as there was too much clinical and methodological heterogeneity in the included studies. Results have been presented in a narrative form. Standard GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) evidence assessment of outco
目的本综述的目的是综合现有的关于药物干预治疗心脏手术后重症监护病房(ICU)成人患者谵妄的有效性和危害的最佳证据。心脏手术患者谵妄的发生率高(50-90%)。谵妄具有有害的影响,增加死亡的风险并对康复产生不利影响。对术后谵妄进行了包括抗精神病药物和镇静剂在内的药物预防和治疗的临床介入试验。这些试验提供了一些关于疗效的证据,并影响了临床决策。然而,许多报告是不完整的,并提供了有偏见的疗效评估;好处被强调,而危害没有得到充分的报道。入选标准:参与者年龄≥16岁,不分性别或种族,在心脏手术后在心胸重症监护室接受治疗,并确定患有谵妄。任何治疗谵妄的药物干预都包括在内,无论药物分类、剂量、强度或给药频率如何。本综述关注的结果是:死亡率、谵妄的持续时间和严重程度、身体约束的使用、生活质量、家属对谵妄管理的满意度、攻击性发作的持续时间/严重程度、相关跌倒、意外自残的严重程度、药理学危害、过度镇静相关的危害、ICU住院时间、住院时间(ICU后)、总住院时间、额外干预药物的需要和抢救药物的需要。首先考虑随机对照试验,如果没有随机对照试验,则考虑非随机对照试验和准实验,然后考虑分析性观察研究。方法检索PubMed、Embase、CINAHL、Web of Science、Cochrane Central Register of Controlled Trials、Scopus、Epistemonikos、Australian New Zealand ClinicalTrials Registry、ClinicalTrials.gov、ClinicalTrials in New Zealand、ProQuest disserthesis and Theses,查找已发表和未发表的研究。搜索没有日期限制。对2012年1月1日至2018年11月17日在相关期刊上发表的初步研究进行了手工检索。只有以英文发表的研究才被纳入考虑。两位审稿人使用来自JBI和麦克马斯特大学的标准化关键评估工具独立评估方法质量。采用标准化的JBI数据提取工具提取定量数据。由于纳入的研究中存在太多的临床和方法学异质性,因此未进行荟萃分析。结果以叙述的形式呈现。标准GRADE(建议、评估、发展和评价的分级)证据评估结果已被报道。结果纳入吗啡与氟哌啶醇对照(n = 53)、昂丹西酮与氟哌啶醇对照(n = 72)、右美托咪定与咪达唑仑对照(n = 80) 3项随机对照试验。由于异质性和不完整的报告,荟萃分析是不可行的。总体而言,这些研究的方法学质量较低。此外,本综述发现,所有三项研究对危害的报告都是不充分和肤浅的,并且不符合危害报告的要求标准,如CONSORT声明扩展对危害的定义。结论吗啡与氟哌啶醇、昂丹司琼与氟哌啶醇、右美托咪定与咪达唑仑治疗心脏手术后谵妄的有效性尚不能得出有效结论。这是由于研究数量少,进行和报告的方法学质量差以及研究之间的异质性。
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引用次数: 6
Dietitian-led clinics in primary care: a scoping review protocol. 初级保健中营养师主导的诊所:范围审查方案。
Pub Date : 2019-08-13 DOI: 10.11124/JBISRIR-D-19-00025
M. Hickson, A. Wanner, A. Collinson
OBJECTIVEThis scoping review aims to examine and map the existing evidence exploring and/or evaluating the implementation, cost and/or effectiveness of dietitian-led clinics in primary care.INTRODUCTIONDietitians may be able to offer new models of care within the primary care setting for relevant diagnosed patients, providing cheaper, more efficient and effective service in comparison to the traditional approach of general practitioner support and referral for specialist treatment. There is some evidence for the efficacy of dietetic care in primary care, but there is a lack of information concerning the broader contribution dietitians may make, including cost effectiveness and the range of conditions that dietitians may successfully manage.INCLUSION CRITERIAEligible studies will explore dietitian or nutritionist-led clinics treating patients with any condition, and will be based in primary care or general practice settings in developed countries. Studies may include experimental, quasi-experimental, observational and qualitative studies.METHODSThe searches will be limited to the past 10 years to ensure retrieved information will be relevant to today's healthcare setting. There will be no limit for language. The following databases will be searched: MEDLINE (Ovid), Embase (Ovid), PsycINFO (Ovid), CINAHL (EBSCO), AMED (EBSCO), British Nursing Index (ProQuest), and Cochrane Database of Systematic Reviews (Wiley). Retrieved papers will be screened for inclusion by at least two reviewers. Where a decision is not possible, full text will be retrieved and reviewed. Data will be extracted from the included papers and a narrative summary will accompany the charted results and will describe how the results relate to the review's objective.
目的:本综述旨在检查和绘制现有的证据,探索和/或评估营养师主导的初级保健诊所的实施、成本和/或有效性。与传统的全科医生支持和专科治疗转诊相比,营养师可能能够在初级保健环境中为相关确诊患者提供新的护理模式,提供更便宜、更高效和更有效的服务。有一些证据表明饮食保健在初级保健中的有效性,但缺乏关于营养师可能做出的更广泛贡献的信息,包括成本效益和营养师可能成功管理的条件范围。纳入标准:符合条件的研究将探索营养学家或营养学家领导的治疗任何疾病患者的诊所,并将以发达国家的初级保健或全科医疗机构为基础。研究可能包括实验、准实验、观察和定性研究。方法搜索将限于过去10年,以确保检索到的信息与当今的医疗保健环境相关。语言将没有限制。将检索以下数据库:MEDLINE (Ovid)、Embase (Ovid)、PsycINFO (Ovid)、CINAHL (EBSCO)、AMED (EBSCO)、British Nursing Index (ProQuest)和Cochrane Database of Systematic Reviews (Wiley)。检索到的论文将由至少两名审稿人筛选纳入。如果无法作出决定,将检索全文并进行审查。数据将从纳入的论文中提取,图表结果将附有叙述性摘要,并将描述结果与综述目标的关系。
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引用次数: 5
Effectiveness and safety of perioperative enteral feeding in patients with burn injuries: a systematic review protocol. 烧伤患者围手术期肠内喂养的有效性和安全性:一项系统评价方案。
Pub Date : 2019-08-01 DOI: 10.11124/JBISRIR-2017-004013
Michelle Cork, Alexa McArthur, Helen Douglas, Fiona Wood

Objective: The objective of this review is to determine whether perioperative enteral feeding improves outcomes in patients with burns.

Introduction: Literature has identified many positive benefits of nutrition support for patients with burn injuries, including preservation of lean body mass, improved wound healing, reduced gastrointestinal permeability and enhanced immunity. Fasting for surgery can undermine the nutritional care of these patients by causing nutrient deficits. It may also negatively affect patient well-being and insulin resistance. Perioperative fasting is intended to protect patients from regurgitation and pulmonary aspiration. This research aims to investigate whether perioperative feeding impacts outcomes in patients with burn injuries.

Inclusion criteria: This systematic review will consider studies whose participants have a burn injury. The intervention is perioperative enteral feeding (either intragastric or post-pyloric). Patients who received perioperative feeding will be compared with patients who had enteral nutrition withheld during the perioperative period. A number of outcome measures will be investigated, including mortality, length of stay, wound infection, wound healing rate and aspiration pneumonia.

Methods: The key databases searched will be PubMed, CINAHL, Embase, Web of Science and Cochrane Central Register of Controlled Trials and Scopus. Only studies published in English will be considered. There will be no date limits. Full texts of selected studies will be retrieved and assessed against inclusion criteria. Studies that do not meet the inclusion criteria will be excluded, with reasons provided. Data synthesis will be pooled in a statistical meta-analysis. Subgroup analysis will be conducted where possible. Where statistical pooling is not possible, the findings will be presented in narrative form.

Systematic review registration number: PROSPERO CRD42018119034.

目的:本综述的目的是确定围手术期肠内喂养是否能改善烧伤患者的预后。文献表明,营养支持对烧伤患者有许多积极的好处,包括保持瘦体重,改善伤口愈合,降低胃肠道通透性和增强免疫力。手术禁食会导致营养缺乏,从而破坏这些患者的营养护理。它还可能对患者的健康和胰岛素抵抗产生负面影响。围手术期禁食旨在保护患者免受反流和肺误吸。本研究旨在探讨围手术期喂养是否会影响烧伤患者的预后。纳入标准:本系统综述将考虑受试者有烧伤的研究。干预措施是围手术期肠内喂养(胃内或幽门后)。接受围手术期喂养的患者将与围手术期停止肠内营养的患者进行比较。将调查一些结果指标,包括死亡率、住院时间、伤口感染、伤口愈合率和吸入性肺炎。方法:检索PubMed、CINAHL、Embase、Web of Science、Cochrane Central Register of Controlled Trials和Scopus等数据库。只考虑以英文发表的研究。没有日期限制。将检索选定研究的全文,并根据纳入标准进行评估。不符合纳入标准的研究将被排除,并说明原因。数据综合将汇集在统计荟萃分析中。如有可能,将进行分组分析。如果统计汇集不可能,调查结果将以叙述形式提出。系统评价注册号:PROSPERO CRD42018119034。
{"title":"Effectiveness and safety of perioperative enteral feeding in patients with burn injuries: a systematic review protocol.","authors":"Michelle Cork,&nbsp;Alexa McArthur,&nbsp;Helen Douglas,&nbsp;Fiona Wood","doi":"10.11124/JBISRIR-2017-004013","DOIUrl":"https://doi.org/10.11124/JBISRIR-2017-004013","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this review is to determine whether perioperative enteral feeding improves outcomes in patients with burns.</p><p><strong>Introduction: </strong>Literature has identified many positive benefits of nutrition support for patients with burn injuries, including preservation of lean body mass, improved wound healing, reduced gastrointestinal permeability and enhanced immunity. Fasting for surgery can undermine the nutritional care of these patients by causing nutrient deficits. It may also negatively affect patient well-being and insulin resistance. Perioperative fasting is intended to protect patients from regurgitation and pulmonary aspiration. This research aims to investigate whether perioperative feeding impacts outcomes in patients with burn injuries.</p><p><strong>Inclusion criteria: </strong>This systematic review will consider studies whose participants have a burn injury. The intervention is perioperative enteral feeding (either intragastric or post-pyloric). Patients who received perioperative feeding will be compared with patients who had enteral nutrition withheld during the perioperative period. A number of outcome measures will be investigated, including mortality, length of stay, wound infection, wound healing rate and aspiration pneumonia.</p><p><strong>Methods: </strong>The key databases searched will be PubMed, CINAHL, Embase, Web of Science and Cochrane Central Register of Controlled Trials and Scopus. Only studies published in English will be considered. There will be no date limits. Full texts of selected studies will be retrieved and assessed against inclusion criteria. Studies that do not meet the inclusion criteria will be excluded, with reasons provided. Data synthesis will be pooled in a statistical meta-analysis. Subgroup analysis will be conducted where possible. Where statistical pooling is not possible, the findings will be presented in narrative form.</p><p><strong>Systematic review registration number: </strong>PROSPERO CRD42018119034.</p>","PeriodicalId":73539,"journal":{"name":"JBI database of systematic reviews and implementation reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11124/JBISRIR-2017-004013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10145837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Association between maternal exposure to pollutant particulate matter 2.5 and congenital heart defects: a systematic review. 母体接触污染物颗粒物质2.5与先天性心脏缺陷之间的关系:一项系统综述。
Pub Date : 2019-08-01 DOI: 10.11124/JBISRIR-2017-003881
Katie C Hall, Jennifer C Robinson

Objective: The objective of this review was to determine if there was an association between maternal exposure to pollutant particulate matter 2.5 during the first trimester of pregnancy and congenital heart defects within the first year of life.

Introduction: The environment is recognized as an important determinant of health for both the individual and population. Air pollution specifically is a major environmental risk factor impacting health with links to asthma, heart disease, obesity, and fetal developmental complications. Of the commonly monitored air pollutants, particulate matter 2.5 has associations with health, especially among vulnerable populations such as children and pregnant women. A congenital heart defect is a fetal complication that impacts 34.3 million infants globally, with more than 80% of the diagnoses having an unknown etiology. Although environmental risk factors such as air pollution are thought to be a risk factor in the diagnosis of a congenital heart defect, epidemiologic research evidence is limited.

Inclusion criteria: This review considered studies that evaluated maternal exposure to the air pollutant particulate matter 2.5 during the first trimester (weeks 1-12) of fetal development. The primary outcome was a diagnosis of a congenital heart defect in an infant within the first year of life.

Methods: A three-step search strategy was utilized in this review and included 11 databases and two websites. Studies published from January 2002 to September 2018 were eligible for inclusion. Only papers published in English were included. Eligible studies underwent critical appraisal by two independent reviewers using standardized critical appraisal instruments from JBI. Quantitative data were extracted from the included studies independently by two reviewers. Odds ratios (ORs) and 95% confidence intervals (CIs) were extracted for the individual outcome measures, specifically atrial septal defect, ventricular septal defect, and tetralogy of fallot, respectively. The defects were identified and pooled, where possible, in statistical meta-analysis. Where statistical pooling was not possible, findings were reported narratively.

Results: Five studies were identified that met the inclusion criteria, including three cohort and two case-control designs. Each individual study identified at least one statistically significant increase or inverse association between particulate matter 2.5 and a congenital heart defect. An increased risk was identified with more than seven isolated and two groupings of congenital heart defects. An inverse risk was identified with two isolated and one grouping of congenital heart defects. Meta-analysis results were: atrial septal defect, OR = 0.65 (95% CI, 0.37 to 1.15); ventricular septal defect, OR = 1.02 (95% CI, 075 to 1.37); and tetralogy of fallot, OR = 1.16 (95% CI, 0.78 to 1.73), indica

目的:本综述的目的是确定母亲在怀孕前三个月接触污染颗粒物2.5与出生后一年内先天性心脏缺陷之间是否存在关联。导言:环境被认为是个人和全体人民健康的一个重要决定因素。特别是空气污染是影响健康的主要环境风险因素,与哮喘、心脏病、肥胖和胎儿发育并发症有关。在通常监测的空气污染物中,颗粒物质2.5与健康有关,特别是对儿童和孕妇等弱势群体而言。先天性心脏缺陷是一种影响全球3430万婴儿的胎儿并发症,其中80%以上的诊断病因不明。虽然空气污染等环境危险因素被认为是诊断先天性心脏缺陷的一个危险因素,但流行病学研究证据有限。纳入标准:本综述考虑了评估孕妇在胎儿发育的前三个月(1-12周)暴露于空气污染物颗粒物2.5的研究。研究的主要结果是在婴儿出生后一年内诊断出先天性心脏缺陷。方法:本综述采用三步搜索策略,包括11个数据库和2个网站。2002年1月至2018年9月发表的研究符合纳入条件。仅收录了以英文发表的论文。合格的研究由两名独立的审稿人使用JBI的标准化关键评估工具进行严格评估。定量数据由两名审稿人独立地从纳入的研究中提取。比值比(ORs)和95%置信区间(CIs)分别用于单独的结果测量,特别是房间隔缺损、室间隔缺损和法洛四联症。在可能的情况下,在统计荟萃分析中识别和汇总缺陷。在无法进行统计汇总的情况下,以叙述方式报告调查结果。结果:5项研究符合纳入标准,包括3项队列设计和2项病例对照设计。每一项单独的研究都确定了至少一项统计上显著的颗粒物2.5与先天性心脏缺陷之间的增加或负相关。风险增加被确定为超过7个孤立和两组先天性心脏缺陷。两个孤立的和一组先天性心脏缺陷被确定为负风险。meta分析结果为:房间隔缺损,OR = 0.65 (95% CI, 0.37 ~ 1.15);室间隔缺损,OR = 1.02 (95% CI, 075 ~ 1.37);法洛四联症,OR = 1.16 (95% CI, 0.78 ~ 1.73),无统计学意义。结论:没有明显的证据支持空气污染物颗粒物质2.5与一岁先天性心脏缺陷之间的联系。然而,很少有研究符合严格的纳入标准,并且这些研究具有高度的异质性,这使得在如此有限的文章数量下完成荟萃分析变得困难。需要进一步的研究来规范结果和污染物监测方法,并提供可比较的分析结果,以便将来进行文献的综合。
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引用次数: 8
Implementing the Richmond Agitation-Sedation Scale in a respiratory critical care unit: a best practice implementation project. 在呼吸重症监护病房实施里士满激动镇静量表:最佳实践实施项目。
Pub Date : 2019-08-01 DOI: 10.11124/JBISRIR-2017-004011
Jui-Yuan Su, C. Lockwood, Yi-Chen Tsou, P. Mu, Shu-Chen Liao, Wei-Chih Chen
INTRODUCTIONAdequate sedation can lead to patient-ventilator synchrony, facilitation of treatment, and decreased physical and psychological discomfort for patients with respiratory failure in the intensive care unit (ICU). The Richmond Agitation-Sedation Scale (RASS) is considered to be the most appropriate tool in sedation assessment.OBJECTIVESThis aim of this project was to implement evidence-based recommendations for sedation assessment using the RASS in mechanically ventilated patients in the ICU.METHODSThis implementation project was conducted in an ICU at a tertiary medical center in Taiwan. Using the JBI Practical Application of Clinical Evidence System software, a baseline audit was conducted in the ICU, followed by an identification of barriers of RASS assessment and an implementation of management of strategies to improve the consistency of sedation assessment.RESULTSResults of the baseline audit showed that four of the six selected criteria had 0% compliance. Following the implementation of the strategies, which included education, visual management and development of a "RASS Reminder Card", there was an improvement in all the criteria audited, with each criterion achieving 83-100% of compliance.CONCLUSIONThe project successfully improved the implementation of RASS assessment in the respiratory ICU. Following the development and implementation of evidence-based resources, a high level of compliance was achieved for nurses using the RASS in the ICU to assess sedation in patients with a ventilator.
适当的镇静可导致重症监护病房(ICU)呼吸衰竭患者与呼吸机同步,促进治疗,减少身心不适。里士满激动镇静量表(RASS)被认为是最合适的镇静评估工具。目的:本项目旨在为ICU机械通气患者使用RASS进行镇静评估提供循证建议。方法本研究在台湾某三级医疗中心的ICU进行。采用JBI临床证据系统实际应用软件,对ICU进行基线审计,识别RASS评估的障碍,实施策略管理,提高镇静评估的一致性。结果基线审计结果显示,6个选定标准中有4个的符合性为0%。在实施包括教育、可视化管理和开发“RASS提醒卡”在内的战略之后,所有审计的标准都有所改善,每个标准的符合率达到83% -100%。结论本项目成功地促进了RASS评估在呼吸内科ICU的实施。随着循证资源的开发和实施,护士在ICU使用RASS评估呼吸机患者的镇静作用时达到了很高的依从性。
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引用次数: 2
Human immunodeficiency virus testing and psychosocial outcomes: a scoping review protocol. 人体免疫缺陷病毒检测与社会心理结果:范围界定审查协议。
Pub Date : 2019-08-01 DOI: 10.11124/JBISRIR-2017-003864
John B Ngobi, Kevin Pottie, Lynne Leonard, Peter Tugwell, Steven J Hoffman, Vivian Welch

Objective: The proposed scoping review will identify psychosocial outcomes immediately following human immunodeficiency virus (HIV) testing and their measurements, specifically among individuals with a new negative or positive test result.

Introduction: No systematic study has described psychosocial outcomes and their measurements in persons immediately following HIV testing. Also, to our knowledge, there is no consensus on a core set of psychosocial outcomes and measurements following HIV diagnosis, which are essential for quality improvement.

Inclusion criteria: All study designs will be considered. Participants with a new positive or negative HIV test result, regardless of sex or age, in any setting will be included. Any measured beneficial or harmful outcomes in the mental and social domains following a new diagnosis will be included. Psychosocial outcomes of participants undergoing treatment and care will be excluded.

Methods: The databases Ovid MEDLINE, Embase and PsycINFO will be searched, and published articles in English from 2007 to the present date will be included. The methods for scoping reviews outlined by the Joanna Briggs Institute will be followed. Data will be extracted from included studies by two reviewers. Any disagreements between the two reviewers will be solved through discussion in a team of five members. To define the specific concepts or outcome (sub)-domains and their measurements, the models proposed by the Outcome Measures in Rheumatology initiative and the Core Outcome Measures in Effectiveness Trials initiative, respectively, will be used. To analyze the data, this study will rely on a multi-level social-ecological model.

目标:拟议的范围界定综述将确定人类免疫缺陷病毒(HIV)检测后的即时社会心理结果及其测量值,特别是在新的阴性或阳性检测结果的个体中:导言:目前还没有系统性的研究描述过 HIV 检测后的心理社会结果及其测量值。此外,据我们所知,目前还没有就 HIV 诊断后的一套核心社会心理结果及其测量方法达成共识,而这对提高质量至关重要:所有研究设计都将被考虑。纳入标准:所有研究设计都将被考虑,HIV 检测结果呈阳性或阴性的参与者,无论性别或年龄,在任何情况下都将被纳入。新诊断后在精神和社会领域的任何有益或有害的测量结果都将包括在内。正在接受治疗和护理的参与者的社会心理结果将被排除在外:将检索 Ovid MEDLINE、Embase 和 PsycINFO 数据库,并纳入 2007 年至今发表的英文文章。将遵循乔安娜-布里格斯研究所(Joanna Briggs Institute)概述的范围界定综述方法。数据将由两名审稿人从纳入的研究中提取。两位审稿人之间的意见分歧将由五人小组讨论解决。在定义具体概念或结果(子)领域及其测量方法时,将分别采用风湿病学结果测量方法倡议和有效性试验核心结果测量方法倡议提出的模型。为了分析数据,本研究将采用多层次的社会生态模型。
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引用次数: 0
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