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Neglected Tropical Diseases in the Central African Region: A Review of their Mass Treatment Coverage 中非地区被忽视的热带病:对其大规模治疗覆盖的审查
Pub Date : 2019-01-01 DOI: 10.26502/jesph.96120063
F. Wirsiy, D. Ako-Arrey, P. Njukeng
Background: The neglected tropical diseases (NTDs) are the most common conditions affecting the poorest 600 million people living in sub-Saharan Africa (SSA) of which the Central African region is part and parcel, and together produce a burden of disease that may be equivalent to one-half of SSA’s malaria disease burden and more than double that caused by tuberculosis. Establishing specific information on the mass treatment coverage would provide a basis for prioritizing control strategies as a means to address the Sustainable Development Goals (SDGs). The objective of this review was to determine the mass treatment coverage trend resulting from 5 NTDs amenable to mass treatment in the Central African region.   Methods: A search on PubMed, ScienceDirect, Uniting to Combat NTDs, Cochrane Library, African Journals Online, MEDLINE, Scopus and Google Scholar with the following Keywords: “Neglected Tropical Diseases”, “Mass Treatment Coverage”, “Control”, “Elimination”, “Lymphatic filariasis”, “Onchocerciasis”, “Schistosomiasis”, “Soil-transmitted helminthiases”, “Trachoma was conducted, with the Medical Subject Headings (MeSH), with specific diseases listed as 5 NTDs amenable to mass treatment per Central Africa region country. Studies to assess the mass treatment coverage resulting from 5 NTDs amenable to treatment in Central Africa as the primary outcome variable, were included. Our search was limited to, articles published from the year 2013 to 2018 (A 5 years review) in English and French. The search identified a total of 140 articles amongst which 10 data-based reports and 5 original articles met the inclusion criteria to give a total of 15 papers that were considered.   Results: Our review shows that, in the Central African region, Cameroon has the highest mass treatment coverage index (58/100) for 5 NTDs while Rwanda, Gabon, Equatorial Guinea, Sao Tome and Principe had mass treatment coverage indexes of 3/100, 1/100, 0/100, 0/100 respectively indicating the need for coordinated action in filling the missing gaps. Also, in the Central African region; over 66 million people received NTD treatment and those who didn’t receive NTD treatment were over 27 million.     Conclusion: There is a need for more data on progress made in reaching people in need of NTD Mass treatment. The way forward paradigm in achieving the control and elimination of NTDs amenable to mass treatment in Central African countries will be to establish, and sustain a task force on NTDs at the African Union, set up a sustainable fund for neglected tropical diseases at the Africa Union, Regularly monitor and report on progress on neglected tropical diseases while recognizing and celebrating countries as they achieve elimination goals. Equally, operational studies on assessing the rate and impact of NTDs mass treatment coverage in the Central African region should be carried out.
背景:被忽视的热带病是影响撒哈拉以南非洲最贫穷的6亿人的最常见疾病,中非地区是撒哈拉以南非洲的重要组成部分,这些疾病加起来造成的疾病负担可能相当于撒哈拉以南非洲疟疾疾病负担的一半,是结核病造成的疾病负担的两倍多。建立关于大规模治疗覆盖率的具体信息将为控制战略的优先次序提供基础,作为实现可持续发展目标的一种手段。本次审查的目的是确定中非区域可进行大规模治疗的5种被忽视热带病的大规模治疗覆盖趋势。方法:检索PubMed、ScienceDirect、Uniting to Combat NTDs、Cochrane Library、African Journals Online、MEDLINE、Scopus和谷歌Scholar,关键词如下:对“被忽视的热带病”、“大规模治疗覆盖率”、“控制”、“消除”、“淋巴丝虫病”、“盘尾丝虫病”、“血吸虫病”、“土壤传播的蠕虫病”、“沙眼”进行了调查,并按医学主题进行了分类,将特定疾病列为中非区域各国可进行大规模治疗的5种被忽视的热带病。纳入了评估中部非洲可治疗的5种被忽视热带病的大规模治疗覆盖率的研究,并将其作为主要结果变量。我们的检索仅限于2013年至2018年(5年回顾)发表的英文和法文文章。检索共确定了140篇文章,其中10篇基于数据的报告和5篇原创文章符合纳入标准,总共有15篇论文被考虑。结果:我们的回顾显示,在中非地区,喀麦隆对5种被忽视热带病的大规模治疗覆盖率指数最高(58/100),而卢旺达、加蓬、赤道几内亚、圣多美和普林西比的大规模治疗覆盖率指数分别为3/100、1/100、0/100和0/100,这表明需要采取协调行动来填补缺失的空白。此外,在中非区域;6600多万人接受了新带病治疗,2700多万人未接受新带病治疗。结论:需要更多的数据来说明在向需要非传染性疾病大规模治疗的人群提供服务方面取得的进展。在中非国家实现控制和消除可大规模治疗的被忽视热带病的前进模式将是在非洲联盟建立和维持一个被忽视热带病工作队,在非洲联盟设立一个被忽视热带病可持续基金,定期监测和报告被忽视热带病的进展情况,同时承认和庆祝实现消除目标的国家。同样,应开展业务研究,评估中非区域被忽视热带病的大规模治疗覆盖率和影响。
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引用次数: 1
A Qualitative Assessment of the Determinants of Adherence to Antiretroviral Therapy among Adolescents living with HIV in the Centre Region of Cameroon 喀麦隆中部地区青少年艾滋病毒感染者坚持抗逆转录病毒治疗决定因素的定性评估
Pub Date : 2019-01-01 DOI: 10.26502/JESPH.96120067
A. Ketchaji, H. Ngouakam, F. Assah, Alexandre Ndjalla, F. Monebenimp, N. Marcelin
Background: Adherence to antiretroviral therapy (ART) is known to be challenging among adolescents living with HIV/AIDS, meanwhile it is the key to success for ART programmes. In Cameroon, although a few researchers have investigated on the quantitative aspects of adherence among adolescents, less is known about qualitative information. This study aimed at investigating the key factors that contribute to ART adherence for adolescents living with HIV in the Centre Region of Cameroon.   Methods: The study was conducted in the Centre Region of Cameroon. Adolescents on ART with disclosed status was recruited from health facilities. Six focus group discussion (FGD) sessions were conducted with 56 adolescents both girls and boys aged more than 15. In addition, 3 FGD with 34 parents/guardians and 10 individual in-depth interviews with health care providers were all conducted between the months of June and September 2018.   Results: A total of 56 adolescents, 34 parents and 10 health care providers were approached for participation. Results showed that a range of factors related to the individual, family, environment, medication and health system levels determine the reasons for poor adherence to ART among adolescents living with HIV. In fact, most adolescents mentioned in this study that compliance with medicine intake is seen as a punishment or drudgery.     Conclusion: In supporting adherence to ART, it would be important to develop approaches that facilitate and help adolescents to adequately comply to medication intake like the creation of discussion groups through phone messages and WhatsApp for the sharing of experiences and for mutual support. A multi-sectorial approach would also be needed to address this issue.
背景:众所周知,在感染艾滋病毒/艾滋病的青少年中,坚持抗逆转录病毒治疗(ART)是一项挑战,同时这也是抗逆转录病毒治疗规划成功的关键。在喀麦隆,虽然一些研究人员调查了青少年依从性的定量方面,但对定性信息知之甚少。本研究旨在调查喀麦隆中部地区感染艾滋病毒的青少年坚持抗逆转录病毒治疗的关键因素。方法:本研究在喀麦隆中部地区进行。从卫生机构招募接受抗逆转录病毒治疗且状况公开的青少年。对56名15岁以上的男女青少年进行了六次焦点小组讨论。此外,在2018年6月至9月期间,对34名家长/监护人进行了3次FGD,并对医疗服务提供者进行了10次个人深度访谈。结果:共接触了56名青少年、34名家长和10名卫生保健提供者。结果表明,与个人、家庭、环境、药物和卫生系统水平相关的一系列因素决定了感染艾滋病毒的青少年抗逆转录病毒治疗依从性差的原因。事实上,在这项研究中提到的大多数青少年,遵守药物摄入被视为一种惩罚或苦役。结论:在支持坚持抗逆转录病毒治疗方面,重要的是制定促进和帮助青少年充分遵守药物摄入的方法,如通过电话短信和WhatsApp创建讨论组,分享经验和相互支持。还需要采取多部门的办法来解决这个问题。
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引用次数: 0
Risky Sexual Behaviours among School-going Adolescent in Malaysia-Findings from National Health and Morbidity Survey 2017 马来西亚学龄青少年的危险性行为——2017年全国健康和发病率调查结果
Pub Date : 2019-01-01 DOI: 10.26502/JESPH.96120059
Noor Aliza Lodz, Mohd Hatta Abd Mutalip, Mohd Amierul Fikri Mahmud, Maria Awaluddin S, N. Yoep, F. Paiwai, Mohd Hazrin Hashim, Maisarah Omar, Noraida Mohamad Kasim, Noor Ani Ahmad
Sexual activities among adolescents poses to sexually transmitted infection (STI) and also unintended pregnancies. This study aims to determine the prevalence of risky sexual activities among school going adolescent in Malaysia. A cross-sectional study with a total of 27,497 secondary school students was done in March-April 2017. A self-administered structured and validated questionnaire was given to answer. The prevalence of ever had sex among adolescents in Malaysia was 7.3% and mostly among males and Indians. The associated factors to sexual activity among adolescents include ever used drugs with aOR=10.201 and ever smoked aOR=1.628. Among those who ever had sex, 87.3% did not use condom, 16.6% had multiple sexual partners and 31.7% had sex before the age of 14 years. The risky sexual behaviours are relatively high among these adolescents. Sexual health educations and programmes in school is vital to prevent any sexual-health related issues among adolescents.
青少年的性活动容易引起性传播感染和意外怀孕。本研究旨在确定马来西亚在校青少年中危险性活动的流行程度。2017年3月至4月,对27,497名中学生进行了一项横断面研究。给出了一份自我管理的结构化和有效的问卷来回答。马来西亚青少年中曾经发生过性行为的患病率为7.3%,主要是男性和印度人。影响青少年性行为的相关因素包括曾吸毒(aOR=10.201)和曾吸烟(aOR=1.628)。在有过性行为的人中,87.3%没有使用安全套,16.6%有多个性伴侣,31.7%在14岁之前发生过性行为。这些青少年的危险性行为相对较高。在学校开展性健康教育和规划对于预防青少年中出现任何与性健康有关的问题至关重要。
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引用次数: 9
Influence of Ambient Air Pollution on Glutathione-S-Transferase Polymorphism Genes-Meta-Analysis 环境空气污染对谷胱甘肽- s-转移酶多态性基因影响的meta分析
Pub Date : 2019-01-01 DOI: 10.26502/jesph.96120075
Sagbo H. Firmin, Lawin Hervé, A. Eugénie, M. Atindehou, C. F. Boris, S. Ambaliou, Ayi-Fanou Lucie
Background: Glutathione-S-Transferase (GST) plays an important role in the detoxication mechanism of our organism but the homozygous deletion of these genes leads to the reduction or suppression of its activity. The aim of this meta-analysis is to evaluate the effect of pollution on GSTM1 and GSTT1 polymorphisms. Methods: Ten publications out of two thousand six hundred fifty nine were consulted using PubMed, Google Scholar, Ovid and the European Journal of Medical Research which related to this topic. All abstracts and publications have been taken into account without restriction of languages. The t-test was used to compare the data of the selected articles. Results: The overall analysis of the data shows that the null GSTM1 and GSTT1 genotype was observed at a higher frequency in the exposed subjects compared to control. Two studies reported that pollution has very significant effects on GSTM1 and GSTT1 but the others studies have shown no significant difference. Conclusion: Ambient air pollution has a negative impact on the expression of GST polymorphism as the deletion which could depend of type of pollutants and population. It would be interesting to conduct others studies to improve our knowledge in individual susceptibility according to the type of population and pollutants.
背景:谷胱甘肽- s -转移酶(GST)在机体解毒机制中发挥着重要作用,但这些基因的纯合缺失会导致其活性降低或抑制。本荟萃分析的目的是评估污染对GSTM1和GSTT1多态性的影响。方法:通过PubMed、谷歌Scholar、Ovid和European Journal of Medical Research查阅与本主题相关的2,659篇出版物中的10篇。所有摘要和出版物均已考虑在内,不受语言的限制。采用t检验比较所选文章的数据。结果:总体数据分析显示,与对照组相比,暴露者中GSTM1和GSTT1基因型为零的频率更高。两项研究报告污染对GSTM1和GSTT1有非常显著的影响,但其他研究没有显示显著差异。结论:环境空气污染对GST多态性的表达有负面影响,而GST多态性的缺失可能与污染物类型和人群有关。根据人口和污染物的类型进行其他研究,以提高我们对个体易感性的认识,这将是有趣的。
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引用次数: 1
Microbiology Community Structure in Bioaerosols and the Respiratory Diseases 生物气溶胶微生物群落结构与呼吸系统疾病
Pub Date : 2019-01-01 DOI: 10.26502/JESPH.96120068
Cai Jiayu, Ren Qiaoqiao, Chen Feilong, Lidan Chen, Wu Jiguo, Wu Zhendong, Chen Lingyun, Rongzhen Liu, Zhang Guoxia
Bioaerosols are crucial indicators of air pollution and play an instrumental role as risk factors when it comes to the adverse health outcome. Bioaerosols are not self-contained pollutant, but a mixture of different compounds, including bacteria, fungi and virus, etc. While several reviews have focused on the health effect of its single component such as bacteria or fungi on public health, there is a dearth of the review studies community structure of bioaerosols and their impact on physiological change, especially the change in lunge function. Herein, this review sheds a light on community structure in different functional areas, clarifying its relevant risk to public health where respiratory diseases, including coughing, runny nose, irritated eyes or throat, allergic rhinitis, aggravation of asthma and fatigue as well as some infectious diseases such as tuberculosis and Legionnaire’s Disease, are particular elaborated. This review will provide some information to adopt accurate and effective control under the circumstances where the medical burden attributes to bioaerosols exposure is spiraling beyond expectation.
生物气溶胶是空气污染的重要指标,当涉及到不利的健康结果时,它作为风险因素发挥着重要作用。生物气溶胶不是自成一体的污染物,而是细菌、真菌和病毒等不同化合物的混合物。虽然一些综述侧重于其单一成分(如细菌或真菌)对公共卫生的健康影响,但缺乏对生物气溶胶群落结构及其对生理变化的影响的综述研究,特别是对弓步功能的变化。在此,本文综述了不同功能区域的社区结构,阐明了其对公共卫生的相关风险,其中特别阐述了呼吸道疾病,包括咳嗽、流鼻涕、眼睛或喉咙发炎、过敏性鼻炎、哮喘和疲劳加重以及一些传染病,如结核病和军团病。这篇综述将为在生物气溶胶暴露导致的医疗负担超出预期的情况下采取准确有效的控制提供一些信息。
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引用次数: 17
Dietary Exposure to Heavy Metal Contaminated Rice and Health Risk to the Population of Monrovia 蒙罗维亚人口从饮食中摄取重金属污染大米及健康风险
Pub Date : 2019-01-01 DOI: 10.26502/jesph.96120077
Lenn G Gomah, R. S. Ngumbu, R. Voegborlo
The aim of this study was to assess the exposure of the population of Monrovia to Heavy metals (Arsenic, Cadmium, Chromium, Lead, Mercury and Nickel) through the consumption of rice and the health risk posed. A total of forty one (41) imported and nineteen (19) locally cultivated rice samples were collected from major markets in Monrovia. A mixture of nitric, per chloric and sulfuric acids were used for complete digestion of the samples and the levels of the metals were determined using ICP-MS and AAS techniques. Dietary exposure of the consumers to the metals was assessed by comparing the Estimated Daily Intake (EDI) to the Provisional Tolerable Daily Intake (PTDI) of the metals, and the potential non-carcinogenic health risk was assessed using Hazard Quotients and Hazard Indices. Carcinogenic health risk from Arsenic was assessed by using Incremental Lifetime Cancer Risk values. Incremental Lifetime Cancer Risk values were less than the US EPA threshold value of 1.00E-04. Hazard Quotients and Hazard Indices for all the metals were less than US EPA permissible value of 1; suggesting that the consumption of the products constitute no potential individual or combined health risk to the population with regards to the tested metals. Although the current levels of heavy metals in the products are negligible, regular monitoring of contaminant levels is highly recommended.
这项研究的目的是评估蒙罗维亚人口通过食用大米接触重金属(砷、镉、铬、铅、汞和镍)的情况及其构成的健康风险。在蒙罗维亚的主要市场共采集了41个进口水稻样本和19个本地种植水稻样本。使用硝酸、盐酸和硫酸的混合物对样品进行完全消化,并使用ICP-MS和原子吸收光谱技术测定金属的含量。通过比较金属的估计每日摄入量(EDI)和临时可耐受每日摄入量(PTDI)来评估消费者对金属的膳食暴露,并使用危害商数和危害指数评估潜在的非致癌健康风险。使用终生癌症风险增量值评估砷的致癌健康风险。终生癌症风险增量值低于美国环保局的阈值1.00E-04。所有金属的危害商数和危害指数均小于美国环保局允许值1;表明产品的消费不会对受测金属对人口构成潜在的个人或综合健康风险。虽然目前产品中的重金属含量可以忽略不计,但强烈建议定期监测污染物水平。
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引用次数: 7
Theory and Practice in Convergence of Revisions of Marine Functional Zoning at Provincial and Municipal Levels: A Case Study of Revision of Putian Marine Functional Zoning in China 省市级海洋功能区划修订衔接的理论与实践——以莆田海洋功能区划修订为例
Pub Date : 2019-01-01 DOI: 10.26502/jesph.96120062
Faming Huang, Yan-Yao Lin, Rongrong Zhao
Marine spatial planning (MSP) promotes the realization of marine ecosystem-based ocean management by regulating the spatial and temporal distribution of human activities in the oceans and coastal areas. Marine functional zoning (MFZ), as an implementation form of marine spatial planning in China, is one of the three major systems defined in the Law of the People's Republic of China on the Administration of Sea Areas. Due to most of the advanced maritime countries in the world adopts “bottom-up management”. The upper level of these countries only plays a strategic and policy guide to the lower level, there was no outstanding the contradiction between the upper and lower levels. However, China adopts an “up-bottom management”, and the upper level has clear constraints and restrictions on the lower level. As a result, there are problems in the process of compiling the marine functional zones in different levels, such as inflexible boundary convergence, single spatial function planning, and unreasonable allocation of control indicators. Therefore, in the process of formulating and implementing MFZ, how to make a good convergence between provincial and municipal levels of MFZ, which had become a pressing problem. This paper studies and discusses the three aspects of the convergence of control boundaries, compatibility of different functions, and the allocation of control indicators in the marine functional zones. It proposed a solution for the convergence between provincial and municipal levels of MFZ, and applied it to the revision and practice of MFZ in Putian, China. The results shown that the research program for the convergence of control boundaries, compatibility of dominant and auxiliary functions in marine functional zones and the allocation of control indicators of provincial and municipal levels in the marine functional zones could realize the effective and reasonable convergence between provincial and municipal levels of MFZ revision. The research results would provide a reference for the revision of provincial and municipal levels of MFZ in other regions of China and the convergence of different levels of MSP in other countries.
海洋空间规划(MSP)通过调节人类活动在海洋和沿海地区的时空分布,促进实现基于海洋生态系统的海洋管理。海洋功能区划是《中华人民共和国海域管理法》确定的三大制度之一,是中国海洋空间规划的一种实施形式。由于世界上大多数先进的海洋国家都采用“自下而上”的管理方式。这些国家的上层只对下层起着战略和政策上的引导作用,并没有突出上层和下层之间的矛盾。但中国实行的是“自上而下的管理”,上层对下层有明确的约束和制约。因此,在编制各级海洋功能区的过程中,存在边界收敛不灵活、空间功能规划单一、控制指标配置不合理等问题。因此,在保税区的制定和实施过程中,如何实现省市级保税区与市级保税区的良好衔接,已成为一个亟待解决的问题。本文从控制边界的收敛性、不同功能的兼容性、海洋功能区控制指标的配置三个方面进行了研究和探讨。提出省市级保税区衔接的解决方案,并将其应用于莆田保税区的修订与实践。结果表明:海洋功能区控制边界的收敛性、主导与辅助功能的兼容性以及海洋功能区省、市两级控制指标的配置研究方案,能够实现保税区修订省、市两级的有效、合理收敛。研究结果可为中国其他地区省市级保密区的修订以及其他国家不同等级保密区的衔接提供参考。
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引用次数: 0
Exposure to Conditions of High Concentrations of Indoor Air Pollutants and Prevalence of ARIs in Children under 5 Years of Age, in Ouagadougou/Burkina Faso 瓦加杜古/布基纳法索5岁以下儿童暴露于高浓度室内空气污染物条件和急性呼吸道感染患病率
Pub Date : 2019-01-01 DOI: 10.26502/jesph.96120065
Kafando Benoit, Savadogo Paul Windinpsidi, M. Tiéba, S. Adama, Sanon Sandrine, Kouanda Seni, S. Blaise
Exposure to PM2.5 in indoor air can cause respiratory infections. In Ouagadougou, concentrations of PM2.5 produced in households using biomass were found to be very high by WHO standards (25 μg/m3 for 24 hours). The objective of this study was to highlight the effect of exposure to high concentrations of PM2.5 emitted during cooking on the prevalence of acute respiratory infections (ARI) in children under 5 years of age. This was a case-control study that took place from 16 September to 15 October 2018 in sector 15 of Ouagadougou. The sample size was 125 cases and 250 controls. Data collection was carried out using a grid, by two nurses, at the CSPS in sector 15 and in households. The cases were children diagnosed with ARI and the controls were children diagnosed with a diagnosis other than ARI. The data were entered using Epi data software and analyzed using Stata 12. The associations were expressed in Odds ratios and their confidence intervals were estimated at 95%. The results showed that the use of biomass in indoor kitchens in residential buildings was linked to the occurrence of ARI in children under the age of 5. Living in a house with several bedrooms was a protective factor. This would be explained by the better ventilation within these households.
接触室内空气中的PM2.5会导致呼吸道感染。在瓦加杜古,根据世卫组织的标准,使用生物质的家庭产生的PM2.5浓度非常高(24小时25 μg/m3)。本研究的目的是强调暴露于烹饪过程中排放的高浓度PM2.5对5岁以下儿童急性呼吸道感染(ARI)患病率的影响。这是一项病例对照研究,于2018年9月16日至10月15日在瓦加杜古第15区进行。样本量为125例和250例对照。数据收集工作由两名护士在15区社区卫生服务中心和住户中使用网格进行。这些病例是被诊断为ARI的儿童,对照组是被诊断为非ARI的儿童。使用Epi数据软件输入数据,并使用Stata 12进行分析。相关性以比值比表示,其置信区间估计为95%。结果表明,在住宅建筑的室内厨房中使用生物质与5岁以下儿童急性呼吸道感染的发生有关。住在有几个卧室的房子里是一个保护因素。这可以解释为这些家庭的通风条件较好。
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引用次数: 2
Determinants of Employee use of Personal Protective Equipment, the Case of Spedag Interfreight Uganda Limited, Kampala 雇员使用个人防护装备的决定因素,以乌干达特快货运有限公司为例,坎帕拉
Pub Date : 2019-01-01 DOI: 10.26502/jesph.96120073
Mildred Ayikoru, Christopher Ddamulira, David Mutekanga
In organizations where neglect of safety gears is common, there are high risks of work-related accidents which can be catastrophic. It is against this backdrop that this study was conducted to assess the determinants of use of personal protective equipment (PPE) at the global interfreight clearance agency SPEDAG based at their premises in Kampala, Uganda. Specifically the study was to establish the level of utilization and the determinants for use of such PPE. The study collected quantitative data using questionnaires from a random sample and qualitative data from purposively selected members of top management (Key informants). The results show a relatively high level (70.1%) use of PPEs, a high positive attitude (95%) towards PPE use and a high (95%) availability of guidelines or policies regarding use of PPEs. The results show that the use of the PPE is taken as pertinent and necessary among the employees. These results were confirmed by the qualitative results from the key informants. The authors concluded that continuous sensitization and sustained availability of guidelines and policies must be strongly supported to maximize use of PPEs. The major recommendation is that policy makers in consultation with work safety practitioners should design policies that are sensitive to the perceptions of the users for effective improved use of PPE.
在忽视安全装置是常见的组织中,有很高的与工作有关的事故风险,这可能是灾难性的。正是在这种背景下,进行了这项研究,以评估设在乌干达坎帕拉的全球货运通关机构SPEDAG使用个人防护装备的决定因素。具体地说,这项研究是为了确定使用这种个人防护装备的水平和决定因素。本研究从随机抽样中收集定量数据,从有目的地选择的高层管理人员(关键线人)中收集定性数据。结果显示PPE的使用水平相对较高(70.1%),对PPE使用的积极态度较高(95%),PPE使用的指导方针或政策可得性较高(95%)。结果表明,员工认为PPE的使用是有针对性和必要的。这些结果得到了关键举报人定性结果的证实。作者得出结论,必须大力支持指南和政策的持续宣传和持续可用性,以最大限度地利用ppe。主要建议是,政策制定者在与工作安全从业人员协商后,应制定对用户的看法敏感的政策,以有效改善个人防护装备的使用。
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引用次数: 7
Risk Factors Associated With Malaria Mortality in Tshwane District, South Africa: A Retrospective Cohort Study, 2011-2014 2011-2014年南非Tshwane地区与疟疾死亡率相关的危险因素:回顾性队列研究
Pub Date : 2019-01-01 DOI: 10.26502/jesph.96120064
Mphaka Mr, M Moshime, Tsilo Lc, C. Reddy
Background: Tshwane District in Gauteng Province identifies malaria cases from endemic provinces and neighbouring countries as well as Odyssean malaria cases. Objectives: To assess changes in malaria morbidity and mortality and to determine risk factors associated with malaria mortality in Tshwane District during 2011-2014.  Methods: A retrospective cohort study was conducted using malaria surveillance data collected by the Communicable Disease Control Directorate in Tshwane district over a period of four years. Only laboratory confirmed cases were enrolled in the study. Secondary death audits were reviewed. Logistic regression determined risk factors associated with malaria mortality.  Results: During 2011-2014, 964 cases were identified. Of these, the median age was 28 years (range: 4 months to 79 years), 71.7% (n=691) were males. The majority of cases, 96.6% (n=931), had travelled to malaria endemic areas within South Africa and neighbouring countries. Of those who travelled to endemic malaria provinces in South Africa, 62.5% (40/64) went to Limpopo. Malaria cases decreased from 333 in 2011 to 229 in 2014. There were 20 deaths (2.1%) and 19 (2.0%) Odyssean malaria cases. Age, gender and malaria season were not associated with mortality. History of travel to a malaria endemic area was a protective factor for mortality (aOR 0.2, 95%CI: 0.36 to 0.78, p=0.021). Conclusion: In this non-endemic district, a number of malaria cases have been reported. Public awareness regarding uptake of antimalarial prophylaxis before and during travel to endemic areas could lead to a reduction in mortality and morbidity in South Africa.
背景:豪登省Tshwane区确定来自流行省份和邻国的疟疾病例以及奥德赛疟疾病例。目的:评估2011-2014年茨瓦内地区疟疾发病率和死亡率的变化,并确定与疟疾死亡率相关的危险因素。方法:利用茨瓦内地区传染病控制局在四年期间收集的疟疾监测数据进行了一项回顾性队列研究。只有实验室确认的病例被纳入研究。对二次死亡审计进行了审查。Logistic回归确定了与疟疾死亡率相关的危险因素。结果:2011-2014年共发现964例。其中,中位年龄为28岁(范围:4个月至79岁),71.7% (n=691)为男性。大多数病例(96.6%)(n=931)曾去过南非及其邻国的疟疾流行地区。在前往南非疟疾流行省份的人中,62.5%(40/64)前往林波波省。疟疾病例从2011年的333例减少到2014年的229例。死亡20例(2.1%),奥德赛疟疾19例(2.0%)。年龄、性别和疟疾季节与死亡率无关。疟疾流行地区旅行史是死亡率的保护因素(aOR: 0.2, 95%CI: 0.36 ~ 0.78, p=0.021)。结论:在这个非流行区,报告了一些疟疾病例。在前往疟疾流行地区之前和期间提高公众对抗疟疾预防措施的认识,可降低南非的死亡率和发病率。
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引用次数: 2
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Journal of environmental science and public health
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