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Cognitive Orientation to daily Occupational Performance (CO-OP) Intervention for People with Cerebral Palsy: A Systematic Review with Meta-Analysis 认知取向对脑瘫患者日常职业表现(CO-OP)干预的meta分析
Pub Date : 2021-01-01 DOI: 10.26502/jppch.74050077
H. Gimeno, M. Jackman, I. Novak
Aim: Cognitive Orientation to daily Occupational Performance (CO-OP) was originally designed for children with Developmental Coordination Disorder but has more recently been applied to the cerebral palsy population who also have disorders of motor function and executive function. The aim of this review was to examine the feasibility, acceptability, and effectiveness of CO-OP in the cerebral palsy population. Methods: A systematic literature review was carried out to identify studies on CO-OP for people with cerebral palsy, using the Medline, CINAHL and ERIC databases between 22 June and 30 June 2021. Results: The search elicited 44 citations, of which 8 studies met eligibility. Five were observational studies (three of five Single Case Experimental Design), three were randomized controlled trials (RCTs), measuring the effects of CO-OP in 100 people with cerebral palsy. Since CO-OP was repurposed to cerebral palsy, initial studies focussed on feasibility, acceptability and J Pediatr Perinatol Child Health 2021; 5 (3): 177-193 DOI: 10.26502/jppch.74050077 Journal of Pediatrics, Perinatology and Child Health 178 preliminary efficacy, and consequently sample sizes were small with high risk of bias. Pooled findings from RCTs indicate CO-OP produces greater gains in goal achievement than to body functions and structure intervention (Standardised Mean Difference 0.86 [95% Confidence Interval 0.20-1.52]). Conclusions: Findings suggest preliminary efficacy of CO-OP for cerebral palsy compared to body functions and structure interventions for goal attainment, with CO-OP having comparable efficacy to other activitiesbased interventions. More clinical trials with adequate power and an individual patient meta-analysis are
目的:日常职业表现的认知取向(CO-OP)最初是为患有发育性协调障碍的儿童设计的,但最近越来越多地应用于患有运动功能和执行功能障碍的脑瘫人群。本综述的目的是研究CO-OP在脑瘫人群中的可行性、可接受性和有效性。方法:在2021年6月22日至6月30日期间,使用Medline、CINAHL和ERIC数据库进行系统文献综述,以确定脑瘫患者CO-OP的研究。结果:检索到44条引用,其中8项研究符合资格。5项为观察性研究(5项单病例实验设计中的3项),3项为随机对照试验(rct),测量了CO-OP对100名脑瘫患者的影响。由于CO-OP被重新用于脑瘫,最初的研究侧重于可行性、可接受性和儿科围产期儿童健康杂志2021;5 (3): 177-193 DOI: 10.26502/jppch.74050077儿科学,围产期和儿童健康杂志178初步疗效,因此样本量小,偏倚风险高。随机对照试验的综合结果表明,CO-OP比身体功能和结构干预更能实现目标(标准化平均差0.86[95%置信区间0.20-1.52])。结论:研究结果表明,与身体功能和结构干预相比,CO-OP治疗脑瘫的初步疗效,CO-OP与其他基于活动的干预具有相当的疗效。更多具有足够功效的临床试验和个体患者荟萃分析
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引用次数: 3
Taming Covid-19 Epidemic in São Paulo with a Logistic Model and Non-Pharmaceutical Measures 用Logistic模型和非药物措施控制<s:1>圣保罗市新冠肺炎疫情
Pub Date : 2021-01-01 DOI: 10.37473/dac/10.1101/2020.05.06.20093666
Marcelo Domingos Marchesin
. In this paper we use the simple logistic mathematical model to represent the development of COVID-19 epidemic in S˜ao Paulo city under quarantine regime and we estimate the total amount of time it is necessary to decrease the number of seriously ill in order to reduce the demand for ICU hospital beds to tolerable levels. Clearly the same reasoning used here can be used for any other city in similar conditions.
. 在本文中,我们使用简单的逻辑数学模型来表示隔离制度下圣保罗市COVID-19流行病的发展,并估计减少重症患者数量所需的总时间,以便将ICU医院床位的需求降低到可接受的水平。显然,这里使用的相同推理可以用于任何其他类似情况的城市。
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引用次数: 0
How Children Perceive COVID-19? Kids Drawings and Perceptions of Parents 儿童如何看待COVID-19?儿童绘画和父母的看法
Pub Date : 2021-01-01 DOI: 10.26502/jppch.74050078
S. Bhamani, Vardah Bharuchi, N. Ali, Dawood Ahmed, A. Makhdoom, Falak Zehra Mohsin, Ramla Hashmi, Sanober Nadeem, Hijaan Mitha, Alyza Muhammad, Mohsina Hussain, F. Shafiq, A. Saleem, Lumaan Sheikh
COVID-19 affected many lives, number of children become stressful and socially isolated. School closure also has great impact on children’s social-emotional development and overall wellbeing. The aim of current study was to identify children’s reactions to COVID-19 and its impact on academic and social life. Qualitative participatory research design was used to assess children perception about COVID-19. Data were collected from parent’s interview and Children drawing. Three major themes include: Fear of the drastic changes, increased sense of responsibility, and gratitude for being at home with family was reported by the parents however children drawings revealed that most J Pediatr Perinatol Child Health 2021; 5 (3): 194-203 DOI: 10.26502/jppch.74050078 Journal of Pediatrics, Perinatology and Child Health 195 of the children felt unhappy and sad because of lock down they were missing things they were missing enjoyed earlier such as school, fiends and outdoor activities and games. This is astonished that most of the children drawn the COVID-19 virus and represented as giant and ugly. Few children also draw mask and other protective measures. Public awareness program on COVID-19 protection and mental health promotion of will be window of opportunity for children psychosocial wellbeing.
COVID-19影响了许多人的生活,许多儿童感到压力和社会孤立。学校关闭对儿童的社会情感发展和整体健康也有很大的影响。本研究的目的是确定儿童对COVID-19的反应及其对学术和社会生活的影响。采用定性参与性研究设计评估儿童对COVID-19的认知。数据来源于家长访谈和儿童绘画。三个主要主题包括:父母报告的对剧烈变化的恐惧、责任感的增强和对与家人在一起的感激之情,但儿童绘画显示,大多数J儿科围产期儿童健康2021;5 (3): 194-203 DOI: 10.26502/jppch.74050078《儿科学、围产期和儿童健康杂志》195名儿童感到不快乐和悲伤,因为他们失去了以前享受过的东西,比如学校、朋友、户外活动和游戏。令人惊讶的是,大多数孩子都画了COVID-19病毒,并被描绘成巨大和丑陋的形象。少数孩子还画口罩等防护措施。2019冠状病毒病保护和促进心理健康的公众意识规划将成为儿童社会心理健康的机会之窗。
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引用次数: 0
Not All Perineal Lesions are Extra-Intestinal Manifestations of Inflammatory Bowel Disease 并非所有会阴病变都是炎症性肠病的肠外表现
Pub Date : 2021-01-01 DOI: 10.26502/jppch.74050079
M. Mahon, Rachel C Blasiak, N. Simmons, D. Levanon
This article is focused on the description of a clinical case that showcases a rare association between Inflammatory Bowel Disease and Hidradenitis Suppurativa. Our primary aim is to highlight this presentation at an atypical timing in the disease course, which necessitated escalation of treatment.
这篇文章的重点是一个临床病例的描述,显示炎症性肠病和化脓性汗腺炎之间的罕见关联。我们的主要目的是强调这种表现在一个非典型的时间在病程中,这需要升级的治疗。
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引用次数: 0
Prevalence of Use of Smart Devices in Children Aged Five Years or Less and Associated Factors in Kuwait 科威特5岁以下儿童使用智能设备的流行程度及其相关因素
Pub Date : 2020-12-17 DOI: 10.21203/rs.3.rs-124857/v1
A. Shamsah, Basma Al-Twari, Fatma Jamal, Latifa Al-farhan, Madawi Al-mass, Abdullah Al-majran, Sara Shamsah
BackgroundThis study aimed to find prevalence of use of smart devices in children aged five years or less and associated factors in KuwaitMethodsA cross-sectional study of 964 parents conducted by distributing a questionnaire. Following the American Academy of Pediatrics (AAP) recommendations for the smart devices use in children, our population was divided into two groups (less than 2 years old and 2-5 years old).Results Reported prevalence of use was 53.2% in children less than 2 years old and 86.3% in 2-5 years old. A significantly higher mean age of fathers was seen in children who used smart devices compared to those who did not in both age groups. The use of smart devices in children less than 2 years was significantly associated with Kuwaiti nationality, family income and governorate. In addition, the higher the family income, the more the use of smart devices. The highest use of smart devices was seen in Capital (60%) and Ahmadi (58.3%). While the lowest was seen in Jahra (30%). In both age groups, most of the parents who reported the smart devices use in their children knew that its use at early age might harm their child. ConclusionYoung children use of smart devices is prevalent in Kuwait. Campaigns need to be carried out to increase parents’ knowledge about the potential risks of smart devices on children’s brains and development.
本研究旨在了解科威特5岁及以下儿童使用智能设备的流行情况及其相关因素。方法对964名家长进行了横断面研究。根据美国儿科学会(AAP)对儿童使用智能设备的建议,我们的人群被分为两组(2岁以下和2-5岁)。结果2岁以下儿童的使用率为53.2%,2-5岁儿童的使用率为86.3%。在两个年龄组中,使用智能设备的孩子的平均父亲年龄明显高于不使用智能设备的孩子。2岁以下儿童智能设备的使用与科威特国籍、家庭收入和省份显著相关。此外,家庭收入越高,智能设备的使用越多。智能设备使用率最高的城市是首都(60%)和艾哈迈迪(58.3%)。而最低的是Jahra(30%)。在这两个年龄组中,大多数报告孩子使用智能设备的父母都知道,在孩子很小的时候使用智能设备可能会伤害他们的孩子。结论科威特儿童智能设备使用普遍。需要开展宣传活动,提高家长对智能设备对儿童大脑和发育的潜在风险的认识。
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引用次数: 2
A scopic review on the diagnostic dilemmas and newer treatment modalities in Hemophagocytic Lymphohistiocytosis 吞噬细胞性淋巴组织增生症的诊断难题和新的治疗方法综述
Pub Date : 2020-10-01 DOI: 10.22541/au.160157518.84491016
Vinod K Paul, V. Rathaur, Amanta L. Ittoop, Rajkumar Sananganba, N. Bhat, Monika Pathania
Abstract: Hemophagocytic lymphohistiocytosis is a rare and fatal systemic illness arising secondary to an immune dysregulation .Primary HLH is due to genetic defects and secondary HLH is caused due to unchecked macrophage recruitment following an acquired trigger. It is often diagnosed late in view of its rarity and similarities of presentation to sepsis and SIRS. A compelete curative solution to this problem is hematopoietic stem cell transplant, though secondary cases are often seen to have sustained remission with immune-chemotherapy COVID 19 has also been postulated to cause a HLH like scenario with blunted NK cell number and function. Recent advances in this field comprising of various immunosuppressant based regimens, myeloablative therapies preceding stem cell transplant and improved techniques of stem cell transplant have improved the outcomes. Here we try to present the pathogenesis, etiology, diagnostic criteria and the dilemmas, various treatment strategies, prognostic markers and the most recent researches regarding this rare disease.
摘要:吞噬细胞性淋巴组织细胞增多症是一种罕见且致命的继发于免疫失调的全身性疾病。原发性HLH是由于遗传缺陷引起的,继发性HLH则是由于后天触发后巨噬细胞未经检查的募集引起的。鉴于其罕见性以及与败血症和SIRS的表现相似性,通常诊断较晚。这个问题的一个强有力的治疗方案是造血干细胞移植,尽管继发性病例通常被认为通过免疫化疗获得持续缓解。新冠肺炎19也被认为会导致类似HLH的情况,NK细胞数量和功能减弱。该领域的最新进展包括各种基于免疫抑制剂的方案、干细胞移植前的清髓疗法和改进的干细胞移植技术,这些都改善了结果。在这里,我们试图介绍这种罕见疾病的发病机制、病因、诊断标准和困境、各种治疗策略、预后标志物以及最近的研究。
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引用次数: 0
Infant and young child feeding practices and nutritional status in two Health Zones of South Kivu, Eastern Democratic Republic of Congo: a community-based study. 刚果民主共和国东部南基伍省两个卫生区的婴幼儿喂养做法和营养状况:基于社区的研究。
Pub Date : 2020-04-05 DOI: 10.21203/rs.3.rs-20693/v1
R. Kambale, G. Ngaboyeka, Joe Bwija Kasengi, Sarah Niyitegeka, Boss Rutakaza Cinkenye, Armanda Baruti, Kizito Chentwali Mutuga, D. Linden
Background In DRC, childhood undernutrition remains a serious public health concern. Internationally recommended infant and young child feeding (IYCF) practices may improve child nutritional status. This study aimed to describe IYCF practices, factors associated with inappropriate complementary feeding, and infant’s nutritional status.Methods A community-based cross-sectional study including 1,009 mother-infant pair was conducted in August 2019 in 32 health areas (16 in rural health zone and 16 in urban one) of South Kivu, Democratic Republic of Congo (DRC), among mothers who had infants under 24 months of age. Infant’s nutritional status was assessed using WHO Anthro plus software. To describe IYCF practices, we used the indicators recommended by the WHO. To study the factors associated with inappropriate complementary feeding practices, we performed univariable and multiple logistic regression analyzes. The data was analyzed in SPSS version 25.Results The prevalence of early initiation of breastfeeding and exclusive breastfeeding up to 6 months of age was 73.7% and 42.2% respectively. Of the 746 infants aged 6–23.9 months, 246 (32.3%) received appropriate complementary feeding. Of the 997 infants who had valid anthropometric parameters, 416 (41.7%) were well-nourished, 374 (37.5%) were undernourished and 207 (20.8%) were overweight. Multivariable logistic regression analysis revealed that residence in rural area [Adjusted Odds Ratio (AOR): 2.38 (95% Confidence Interval (CI): 1.49, 3.78)], non-attendance at postnatal care (AOR 1.63; 95% CI 1.12, 2.96), low household socioeconomic (AOR 1.72; 95% CI 1.14, 2.59) and low maternal education (AOR 1.83; 95% CI 1.20, 2.77) were factors associated with inappropriate complementary feeding. Mothers with inappropriate complementary feeding practices were 6.88 times more likely to have undernourished infants than their counterparts (AOR 6.88; 95% CI 1.24, 18.37).Conclusion Findings from this study provide strong evidence, both of association between inappropriate complementary feeding and undernutrition, and of the double burden of malnutrition with the co-existence of under- and overnutrition in the infant population in South Kivu. Interventions should focus on both preventing undernutrition and overweight to promote child well-being.
背景在刚果民主共和国,儿童营养不良仍然是一个严重的公共卫生问题。国际推荐的婴幼儿喂养(IYCF)做法可以改善儿童的营养状况。本研究旨在描述国际婴儿营养日的做法、与不适当补充喂养相关的因素以及婴儿的营养状况。方法2019年8月,在刚果民主共和国南基伍的32个卫生区(16个在农村卫生区,16个在城市卫生区),对有24个月以下婴儿的母亲进行了一项基于社区的横断面研究,包括1009对母婴。使用世界卫生组织Anthro-plus软件评估婴儿的营养状况。为了描述国际儿童基金会的做法,我们使用了世界卫生组织建议的指标。为了研究与不适当的补充喂养做法相关的因素,我们进行了单变量和多元逻辑回归分析。结果6个月龄早期母乳喂养和纯母乳喂养的患病率分别为73.7%和42.2%。746名6至23.9个月大的婴儿中,246名(32.3%)接受了适当的补充喂养。在拥有有效人体测量参数的997名婴儿中,416名(41.7%)营养良好,374名(37.5%)营养不良,207名(20.8%)超重。多变量logistic回归分析显示,居住在农村地区[调整后的比值比(AOR):2.38(95%置信区间(CI):1.49,3.78)],未参加产后护理(AOR 1.63;95%置信区间1.12,2.96),家庭社会经济水平低(AOR 1.72;95%CI 1.14,2.59)和母亲教育水平低(AOR 1.83;95%CI 1.20,2.77)是与不适当补充喂养相关的因素。补充喂养不当的母亲发生营养不良婴儿的可能性是母亲的6.88倍(AOR 6.88;95%CI 1.24,18.37),以及营养不良与南基伍婴儿营养不足和营养过剩并存的双重负担。干预措施应侧重于预防营养不良和超重,以促进儿童福祉。
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引用次数: 1
Comparison of “Comfort” Score for Pain Performed by Nursing Staff and Primary Investigator in Paediatric Mechanically Ventilated Patients in a Tertiary Health Care Centre 某三级医疗保健中心儿童机械通气患者中护理人员与主要研究者疼痛“舒适”评分的比较
Pub Date : 2020-01-01 DOI: 10.26502/jppch.74050053
K. Upasana, R. Chhabra, P. Maheshwari
Context: Mechanical ventilation can be traumatic despite administration of sedatives. Sedation can mask uncontrolled pain for intubated patients and prevent them from communicating it. An optimal scoring system for sedation and analgesia can facilitate comparisons. Aims: Compare the COMFORT score performed by the nursing staff on paediatric mechanically ventilated patients to the one performed by the principal investigator. Settings and Design: This Prospective observational study was conducted in a tertiary care hospital. Sixty five patients fulfilling the inclusion criteria were included. Methods and Material: COMFORT scoring was performed by the nursing staff in Paediatric Intensive Care Unit (PICU) on all ventilated patients three times each day. The primary investigator performed the scoring at the same time, but independent of the staff, to enable comparison. Statistical analysis used: Statistical testing has been conducted with the statistical package version SPSS 20.0. For all statistical tests, a p value <0.05 will be taken to indicate a significant difference/association. Results: Our study showed significant difference in assessment of COMFORT score by the investigator and nursing staff. Of our patients, 44.6% were over sedated and 55.4% were optimally sedated. None were under sedated. No correlation was noted between the duration of intubation, age, gender, indication of intubation and type of cases with COMFORT score. However, significant association was found between COMFORT score and outcome of the patient, with lower scores for those who died in comparison to survivors. Conclusions: Presence of dedicated person for pain assessment can lead to more efficient management.
背景:尽管使用了镇静剂,机械通气仍可能造成创伤。镇静可以掩盖插管患者无法控制的疼痛,并阻止他们传达疼痛。一个最优的镇静和镇痛评分系统可以方便比较。目的:比较护理人员对儿科机械通气患者进行的COMFORT评分与主要研究者进行的评分。背景和设计:本前瞻性观察研究在一家三级保健医院进行。65例符合纳入标准的患者被纳入。方法和材料:由儿科重症监护病房(PICU)的护理人员对所有通气患者进行COMFORT评分,每天3次。主要研究者在同一时间进行评分,但独立于工作人员,以便进行比较。使用的统计分析:使用SPSS 20.0版本的统计软件包进行统计检验。对于所有统计检验,p值<0.05表示有显著差异/关联。结果:我们的研究显示研究者和护理人员对舒适度评分的评估有显著差异。在我们的患者中,44.6%过度镇静,55.4%处于最佳镇静状态。没有人服用镇静剂。气管插管时间、年龄、性别、气管插管指征与病例类型舒适度评分无相关性。然而,舒适度评分与患者预后之间存在显著关联,与幸存者相比,死亡患者的舒适度评分较低。结论:有专门的人员进行疼痛评估可以更有效地管理。
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引用次数: 0
Prevalence and Clinical Outcome of Inborn Neonates with Hypoglycaemia at the Point of Admission as seen in Rivers State University Teaching Hospital, Nigeria 尼日利亚河流州立大学教学医院低血糖新生儿入院时的患病率和临床结果
Pub Date : 2020-01-01 DOI: 10.26502/jppch.74050054
West Ba, Aitafo Je
. Abstract Background: Neonatal hypoglycaemia is one of the commonest abnormalities of the newborn which, if unrecognized may result in poor neurologic development, poor intellectual functions, seizures or even death. This study was therefore carried out to determine the prevalence of hypoglycaemia, its’ associated risk factors and clinical outcome among inborn neonates. Methodology: This prospective study was conducted in the Neonatal Unit of the Rivers State University teaching Hospital from April 2019 to March 2020. Results: Of the 468 neonates admitted, 71 (15.2%) had hypoglycaemia with M:F ratio of 1.6:1. Hypoglycaemia was more common with presentations on the first day of life, those who commenced breastfeeding from day 2 of admission and above and had hypothermia. The commonest clinical features in hypoglycaemic neonates were difficulty in breathing (45.1%), seizures (7.0%) and cyanosis (5.6%), although there was no statistical significance (P>0.05). Maternal risk
. 背景:新生儿低血糖是新生儿最常见的异常之一,如果不及时发现,可能导致神经发育不良、智力功能低下、癫痫发作甚至死亡。因此,本研究旨在确定新生儿中低血糖的患病率、相关危险因素和临床结果。方法:本前瞻性研究于2019年4月至2020年3月在河流州立大学教学医院新生儿病房进行。结果:468例新生儿中,低血糖71例(15.2%),M:F比为1.6:1。低血糖在出生第一天更常见,那些从入院第2天及以上开始母乳喂养并出现体温过低的人。低血糖新生儿最常见的临床特征是呼吸困难(45.1%)、癫痫发作(7.0%)和发绀(5.6%),但差异无统计学意义(P < 0.05)。产妇风险
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引用次数: 0
Uniparental Disomy Leading to a Rare Juvenile Form of ALS. 单亲畸形导致罕见的少年型ALS。
Pub Date : 2020-01-01 Epub Date: 2020-10-10 DOI: 10.26502/jppch.74050049
Yigit Karasozen, Kazim A Sheikh, Pedro Mancias, Thy P Nguyen
2. Case Presentation Our patient is a 27 year old woman of Nicaraguan descent, who presented to to an orthopedist for toe walking at age 5. She was born to a 31 year old G2P2 mother via vaginal delivery after a full term, uncomplicated gestation. She met all early milestones for motor, language, cognitive, and social development until she started to show symptoms at the age of 4. Over the years, she developed progressive symptoms of muscle weakness with significant atrophy involving her distal arms and legs with development of bilateral pes cavus deformities, foot drop and significant intrinsic hand weakness.
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引用次数: 1
期刊
Journal of pediatrics, perinatology and child health
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