首页 > 最新文献

Journal of trace elements and minerals最新文献

英文 中文
Cognitive- and memory-enhancing activity of Cinnamon (Cinnamomum zeylanicum) aqueous extract in lead acetate-exposed rats 肉桂(Cinnamomum zeylanicum)水提取物对暴露于醋酸铅的大鼠的认知和记忆增强活性
Pub Date : 2024-08-13 DOI: 10.1016/j.jtemin.2024.100189

Background

Lead (Pb) exposure has been linked to reduced academic performance, lower IQ, cognitive and memory impairments, and other psychiatric conditions such as depression and anxiety. Natural antioxidants and dietary sources of phytochemicals, including Cinnamomum zeylanicum (CZ), have been investigated to possibly replace the current adverse reacting drugs used to treat Pb poisoning. Consequently, this study evaluated the activity of CZ against Pb-mediated neurotoxicity.

Methods

Wistar rats were assigned into six groups (n = 8) namely: Control; Lead acetate (Pb; 100 mg kg−1 body weight [BW]); CZ-pre-treated groups (CZ1 [200 mg.kg−1 BW] + Pb and CZ2 [400 mg kg−1 BW] + Pb); and CZ-only groups (CZ1 and CZ2). After 28 days, neurobehavioral, antioxidant, lipid peroxidation, nitric oxide, and Pb concentration levels, as well as hippocampal and cerebral histology, were evaluated.

Results

Findings showed a significant reduction (p < 0.05) in final body and whole brain weights, cognition, and memory impairments, dysregulation of antioxidant enzymes, lipid peroxidation, and elevated nitric oxide as well as high Pb concentrations in the hippocampus and cerebrum of Pb-exposed rats following comparison to the control and CZ pretreated rats. Histological findings revealed morphological alterations with vacuolated tissue architecture in the hippocampus and cerebrum of Pb-exposed rats while the rats pre-treated with CZ showed similar morphology to the control rats.

Conclusion

Altogether, the findings showed that CZ was not toxic to the rats but protected against Pb toxicity, mediated possibly through its potent antioxidant, nitric oxide scavenging, and metal chelation activity.

背景铅(Pb)暴露与学习成绩下降、智商降低、认知和记忆障碍以及抑郁和焦虑等其他精神疾病有关。人们一直在研究天然抗氧化剂和膳食来源的植物化学物质,包括桂皮(CZ),以取代目前用于治疗铅中毒的不良反应药物。因此,本研究评估了 CZ 对铅介导的神经毒性的活性:对照组;醋酸铅组(Pb;100 mg kg-1 体重[BW]);CZ 预处理组(CZ1 [200 mg.kg-1 BW] + Pb 和 CZ2 [400 mg kg-1 BW] + Pb);以及仅 CZ 组(CZ1 和 CZ2)。28 天后,对神经行为、抗氧化剂、脂质过氧化、一氧化氮和铅浓度水平以及海马和大脑组织学进行了评估。05)、认知和记忆障碍、抗氧化酶失调、脂质过氧化、一氧化氮升高以及铅在铅暴露大鼠海马和大脑中的高浓度。组织学研究结果表明,暴露于铅的大鼠海马和大脑的组织结构发生了空泡化的形态改变,而使用 CZ 预处理的大鼠则表现出与对照组大鼠相似的形态。
{"title":"Cognitive- and memory-enhancing activity of Cinnamon (Cinnamomum zeylanicum) aqueous extract in lead acetate-exposed rats","authors":"","doi":"10.1016/j.jtemin.2024.100189","DOIUrl":"10.1016/j.jtemin.2024.100189","url":null,"abstract":"<div><h3>Background</h3><p>Lead (Pb) exposure has been linked to reduced academic performance, lower IQ, cognitive and memory impairments, and other psychiatric conditions such as depression and anxiety. Natural antioxidants and dietary sources of phytochemicals, including <em>Cinnamomum zeylanicum</em> (CZ), have been investigated to possibly replace the current adverse reacting drugs used to treat Pb poisoning. Consequently, this study evaluated the activity of CZ against Pb-mediated neurotoxicity.</p></div><div><h3>Methods</h3><p>Wistar rats were assigned into six groups (<em>n</em> = 8) namely: Control; Lead acetate (Pb; 100 mg kg<sup>−1</sup> body weight [BW]); CZ-pre-treated groups (CZ1 [200 mg.kg<sup>−1</sup> BW] + Pb and CZ2 [400 mg kg<sup>−1</sup> BW] + Pb); and CZ-only groups (CZ1 and CZ2). After 28 days, neurobehavioral, antioxidant, lipid peroxidation, nitric oxide, and Pb concentration levels, as well as hippocampal and cerebral histology, were evaluated.</p></div><div><h3>Results</h3><p>Findings showed a significant reduction (<em>p</em> &lt; 0.05) in final body and whole brain weights, cognition, and memory impairments, dysregulation of antioxidant enzymes, lipid peroxidation, and elevated nitric oxide as well as high Pb concentrations in the hippocampus and cerebrum of Pb-exposed rats following comparison to the control and CZ pretreated rats. Histological findings revealed morphological alterations with vacuolated tissue architecture in the hippocampus and cerebrum of Pb-exposed rats while the rats pre-treated with CZ showed similar morphology to the control rats.</p></div><div><h3>Conclusion</h3><p>Altogether, the findings showed that CZ was not toxic to the rats but protected against Pb toxicity, mediated possibly through its potent antioxidant, nitric oxide scavenging, and metal chelation activity.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000740/pdfft?md5=6614671d6c0daa8be92d3b55240d32b6&pid=1-s2.0-S2773050624000740-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The analysis of the essential metal contents in khat (Catha edulis Forsk) from Meru County, Kenya 肯尼亚梅鲁县卡塔叶(Catha edulis Forsk)中的基本金属含量分析
Pub Date : 2024-08-12 DOI: 10.1016/j.jtemin.2024.100188

Background

Chemical composition of plants has attracted considerable interest in recent years with considerable research tailored into determining metal contents in food substances. Particularly, essential elements which are necessary for normal human body functioning and are strongly recommended in optimal proportions for better health. This study determined the levels of essential elements; calcium (Ca), magnesium (Mg), sodium (Na), potassium (K) and manganese (Mn) in eleven khat (Catha edulis Forsk) samples collected from Meru County.

Methodology

1.0 g of dry ground khat samples were wet-digested in a solvent mixture of 10 mL of HCl, HNO3 and 20 vol of H2O2 for 3 h at variable temperature of 50–90 °C and later reconstituted in 25 mL 0.05 molL1 HCl before analysis. The samples were analyzed using inductively coupled plasma atomic emission spectrometry (ICP AES) after acid digestion whereas Hierarchical cluster analysis (HCA) and principal component analysis (PCA) were used to investigate elemental characteristics and determine the sources of essential metals in khat. In addition, Pearson correlation coefficient (PCC) was used to evaluate the relationships between the essential metals.

Results

Spinach leaves certified reference material (CRM 1750a) was analyzed and the percentage recoveries (%) of 98.4 and 101.7 determined showing that the digestion method employed in this work had adequate accuracy. The validated method was employed for the analysis of all the khat samples. The analyzed metal concentration ranges (mg100g1) in fresh-weight basis per day of five metals were 160.9–267.3, 44.6–81.7, 2.0–3.0, 237.6–393.6, and 220.3 -349.0 for Ca, Mg, Mn, K, and Na, respectively. Both HCA and PCA results showed that these elements could be linked to natural soils and anthropogenic sources. PCC reported significant correlations between Na and K indicating they may have been derived from the same source. The daily metal intakes were below the World Health Organization (WHO) permissible limits implying no associated health risks for khat users.

Conclusion

Based on the findings of this study, the consumption of khat from regions of Meru County may be a potential source for essential elements required for human biological processes.

背景植物的化学成分近年来引起了人们的极大兴趣,大量研究都集中在确定食品物质中的金属含量上。特别是人体正常运作所必需的基本元素,强烈建议采用最佳比例以改善健康。本研究测定了从梅鲁县采集的 11 份阿拉伯茶(Catha edulis Forsk)样本中的基本元素含量:钙(Ca)、镁(Mg)、钠(Na)、钾(K)和锰(Mn)。在 50-90 °C 的变温条件下,将 0 g 干燥的阿拉伯茶叶样品在 10 mL HCl、HNO3 和 20 vol H2O2 的混合溶剂中湿法消化 3 小时,然后在 25 mL 0.05 molL-1 HCl 中重组,再进行分析。样品经酸性消解后,采用电感耦合等离子体原子发射光谱法(ICP AES)进行分析,同时采用层次聚类分析(HCA)和主成分分析(PCA)来研究阿拉伯茶中的元素特征并确定其基本金属的来源。此外,还使用了皮尔逊相关系数(PCC)来评估基本金属之间的关系。结果分析了菠菜叶认证参考材料(CRM 1750a),确定的回收率(%)分别为 98.4 和 101.7,表明这项工作中使用的消化方法具有足够的准确性。所有阿拉伯茶叶样品的分析都采用了这种经过验证的方法。以鲜重为基准,每天分析的五种金属浓度范围(毫克 100 克-1)分别为 160.9-267.3、44.6-81.7、2.0-3.0、237.6-393.6 和 220.3-349.0(Ca、Mg、Mn、K 和 Na)。HCA 和 PCA 结果表明,这些元素可能与天然土壤和人为来源有关。据 PCC 报告,Na 和 K 之间存在明显的相关性,表明它们可能来自同一来源。每日金属摄入量低于世界卫生组织(WHO)的允许限值,这意味着阿拉伯茶使用者没有相关的健康风险。
{"title":"The analysis of the essential metal contents in khat (Catha edulis Forsk) from Meru County, Kenya","authors":"","doi":"10.1016/j.jtemin.2024.100188","DOIUrl":"10.1016/j.jtemin.2024.100188","url":null,"abstract":"<div><h3>Background</h3><p>Chemical composition of plants has attracted considerable interest in recent years with considerable research tailored into determining metal contents in food substances. Particularly, essential elements which are necessary for normal human body functioning and are strongly recommended in optimal proportions for better health. This study determined the levels of essential elements; calcium (Ca), magnesium (Mg), sodium (Na), potassium (K) and manganese (Mn) in eleven khat (<em>Catha edulis</em> Forsk) samples collected from Meru County.</p></div><div><h3>Methodology</h3><p>1.0 g of dry ground khat samples were wet-digested in a solvent mixture of 10 mL of HCl, HNO<sub>3</sub> and 20 vol of H<sub>2</sub>O<sub>2</sub> for 3 h at variable temperature of 50–90 °C and later reconstituted in 25 mL 0.05 <span><math><mrow><mrow><mtext>mol</mtext><mspace></mspace></mrow><msup><mrow><mi>L</mi></mrow><mrow><mo>−</mo><mn>1</mn></mrow></msup></mrow></math></span> HCl before analysis. The samples were analyzed using inductively coupled plasma atomic emission spectrometry (ICP AES) after acid digestion whereas Hierarchical cluster analysis (HCA) and principal component analysis (PCA) were used to investigate elemental characteristics and determine the sources of essential metals in khat. In addition, Pearson correlation coefficient (PCC) was used to evaluate the relationships between the essential metals.</p></div><div><h3>Results</h3><p>Spinach leaves certified reference material (CRM 1750a) was analyzed and the percentage recoveries (%) of 98.4 and 101.7 determined showing that the digestion method employed in this work had adequate accuracy. The validated method was employed for the analysis of all the khat samples. The analyzed metal concentration ranges (<span><math><mrow><mtext>mg</mtext><mspace></mspace><mn>100</mn><msup><mrow><mrow><mi>g</mi></mrow></mrow><mrow><mo>−</mo><mn>1</mn></mrow></msup></mrow></math></span>) in fresh-weight basis per day of five metals were 160.9–267.3, 44.6–81.7, 2.0–3.0, 237.6–393.6, and 220.3 -349.0 for Ca, Mg, Mn, K, and Na, respectively. Both HCA and PCA results showed that these elements could be linked to natural soils and anthropogenic sources. PCC reported significant correlations between Na and K indicating they may have been derived from the same source. The daily metal intakes were below the World Health Organization (WHO) permissible limits implying no associated health risks for khat users.</p></div><div><h3>Conclusion</h3><p>Based on the findings of this study, the consumption of khat from regions of Meru County may be a potential source for essential elements required for human biological processes.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000739/pdfft?md5=4a3295a498fef5b584bce8ce5f7791cc&pid=1-s2.0-S2773050624000739-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concentrations, sources and exposure to metals in dust from automobile mechanic workshops in Nigeria 尼日利亚汽车修理厂粉尘中金属的浓度、来源和接触情况
Pub Date : 2024-08-06 DOI: 10.1016/j.jtemin.2024.100186

Background

Dust is ubiquitous and humans are unavoidably in constant contact with it. Therefore, exposure to metal-laden dust from workplaces can be a serious threat to human health.

Objective

The objective of this study was to assess the concentrations of nine metals, namely, Cd, Pb, Cr, Ni Cu, Co, Mn, Zn and Fe, in dust from automobile mechanic workshops (AMWs) in urban and semi-urban areas of Delta State, Nigeria.

Methods

The dust samples were digested in aqua-regia and their metal content was determined by atomic absorption spectrometry.

Results

The concentrations of metals (mg kg-1) in dust from the AMWs ranged from 0.12 to 4.20 for Cd, 11.3 to 3900 for Pb, 9.05 to 45.3 for Cr, 0.35 to 345 for Ni, 170 to 56,400 for Cu, 1.05 to 31.4 for Co, 51.3 to 310 for Mn, 143 to 634 for Zn, and 70,900 to 258,000 for Fe. The pollution indices indicated that Cd, Cu, Pb and Zn were the prominent contaminants in dust from the AMWs. Children's exposure to metal-laden dust from the AMWs could elicit adverse non-carcinogenic health effects. The carcinogenic risk values obtained for human exposure to metals in dust from the AMWs were above the safe level indicating possible induction of cancer or cancer-related illnesses. The sources of metals in dust from the AMWs are related to automobile emissions and discharges from vehicular components.

Conclusion

The activities in AMWs are potent sources of metals to the environment, especially Cd, Cu, Pb and Zn. Therefore, this study recommends regulatory control of activities conducted in AMWs so as to minimize widespread metal contamination and the consequent impact of metals in the affected dust on humans and the environment.

背景粉尘无处不在,人类不可避免地经常接触粉尘。本研究的目的是评估尼日利亚三角洲州城市和半城市地区汽车修理厂(AMWs)粉尘中的九种金属,即镉、铅、铬、镍、铜、钴、锰、锌和铁的浓度。方法将粉尘样本在水沉淀法中消化,用原子吸收光谱法测定其金属含量。镉为 0.12 至 4.20,铅为 11.3 至 3 900,铬为 9.05 至 45.3,镍为 0.35 至 345,铜为 170 至 56 400,钴为 1.05 至 31.4,锰为 51.3 至 310,锌为 143 至 634,铁为 70 900 至 258 000。污染指数表明,镉、铜、铅和锌是机加工粉尘中的主要污染物。儿童暴露于含金属的粉尘中会对健康产生非致癌的不良影响。人 类 摄 取 到 的 致 癌 风 险 值 高 于 安 全 水 平 , 显 示 可 能 会 引 致 癌 症 或 与 癌 症 有 关 的 疾 病 。机 动 工 程 厂 尘 埃 中 的 金 属 来 源 与 汽 车 排 放 物 及 车 辆 组 件 排 放 物 有 关 。因此,本研究建议对在非机动车厂进行的活动进行监管,以尽量减少大范围的金属污染以及受影响粉尘中的金属对人类和环境造成的影响。
{"title":"Concentrations, sources and exposure to metals in dust from automobile mechanic workshops in Nigeria","authors":"","doi":"10.1016/j.jtemin.2024.100186","DOIUrl":"10.1016/j.jtemin.2024.100186","url":null,"abstract":"<div><h3>Background</h3><p>Dust is ubiquitous and humans are unavoidably in constant contact with it. Therefore, exposure to metal-laden dust from workplaces can be a serious threat to human health.</p></div><div><h3>Objective</h3><p>The objective of this study was to assess the concentrations of nine metals, namely, Cd, Pb, Cr, Ni Cu, Co, Mn, Zn and Fe, in dust from automobile mechanic workshops (AMWs) in urban and semi-urban areas of Delta State, Nigeria.</p></div><div><h3>Methods</h3><p>The dust samples were digested in aqua-regia and their metal content was determined by atomic absorption spectrometry.</p></div><div><h3>Results</h3><p>The concentrations of metals (mg kg<sup>-1</sup>) in dust from the AMWs ranged from 0.12 to 4.20 for Cd, 11.3 to 3900 for Pb, 9.05 to 45.3 for Cr, 0.35 to 345 for Ni, 170 to 56,400 for Cu, 1.05 to 31.4 for Co, 51.3 to 310 for Mn, 143 to 634 for Zn, and 70,900 to 258,000 for Fe. The pollution indices indicated that Cd, Cu, Pb and Zn were the prominent contaminants in dust from the AMWs. Children's exposure to metal-laden dust from the AMWs could elicit adverse non-carcinogenic health effects. The carcinogenic risk values obtained for human exposure to metals in dust from the AMWs were above the safe level indicating possible induction of cancer or cancer-related illnesses. The sources of metals in dust from the AMWs are related to automobile emissions and discharges from vehicular components.</p></div><div><h3>Conclusion</h3><p>The activities in AMWs are potent sources of metals to the environment, especially Cd, Cu, Pb and Zn. Therefore, this study recommends regulatory control of activities conducted in AMWs so as to minimize widespread metal contamination and the consequent impact of metals in the affected dust on humans and the environment.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000715/pdfft?md5=cc9761780517123bf3b3d669bf007b83&pid=1-s2.0-S2773050624000715-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142136413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum zinc status of patients with colorectal cancer: A systematic review and meta-analysis 结直肠癌患者的血清锌状况:系统回顾和荟萃分析
Pub Date : 2024-08-04 DOI: 10.1016/j.jtemin.2024.100185

Introduction

Among the increasing number of cancer cases, colorectal cancer (CRC) cases are rising globally. The association of zinc in the neoplastic process of CRC is a major research avenue, yet the published reports have not provided any definitive conclusion.

Objectives

We examined the association between serum zinc levels and CRC to test the potential of zinc dysregulation as a CRC susceptibility factor.

Methods

In this systemic review and meta-analysis, we extensively searched EBSCOhost, EMBASE, Cochrane Library, ProQuest, PubMed/MEDLINE, Scopus, and Web of Science as well as manual screening by subject experts for studies reporting serum/plasma/blood zinc levels in CRC patients and control subjects till 27th August 2023. Based on a random effect model, we estimated the mean difference in serum/plasma/blood zinc levels between CRC cases and control subjects. Subgroup differences and publication bias were also investigated, along with a critical appraisal of included studies.

Results

Eighteen studies with 8330 participants were included. The difference in serum zinc between CRC patients and control subjects was –5.01 µg/dl [95 % CI: −21.76 to 11.74; p = 0.56]. Omitting a highly influential outlier study, made this difference statistically significant at –13.28 µg/dl [95 % CI: −20.66 to -5.90, p < 0.01]. The difference between study effects could not be explained by the difference in analytical methods for zinc assessment, or type of blood samples.

Conclusion

CRC patients had lower serum zinc levels. Some factors, such as different tumor grades of CRC, adenomas, and colonic polyps need to be further considered for a more conclusive association between serum zinc levels and risk for CRC.

导言在癌症病例不断增加的过程中,结直肠癌(CRC)病例在全球范围内呈上升趋势。我们研究了血清锌水平与 CRC 之间的关系,以检验锌失调作为 CRC 易感因素的可能性。方法在本系统综述和荟萃分析中,我们广泛检索了 EBSCOhost、EMBASE、Cochrane Library、ProQuest、PubMed/MEDLINE、Scopus 和 Web of Science,并由主题专家人工筛选了截至 2023 年 8 月 27 日报告 CRC 患者和对照组血清/血浆/血液锌水平的研究。基于随机效应模型,我们估算了 CRC 病例与对照组之间血清/血浆/血液锌水平的平均差异。我们还调查了亚组差异和发表偏倚,并对纳入的研究进行了批判性评估。CRC患者与对照组之间的血清锌差异为-5.01 µg/dl [95 % CI: -21.76 to 11.74; p = 0.56]。剔除一项影响较大的离群研究后,这一差异达到了统计学意义上的-13.28 µg/dl [95 % CI: -20.66 to -5.90, p < 0.01]。研究效果之间的差异无法用锌评估分析方法或血样类型的不同来解释。需要进一步考虑一些因素,如不同肿瘤等级的 CRC、腺瘤和结肠息肉,以确定血清锌水平与 CRC 风险之间的关系。
{"title":"Serum zinc status of patients with colorectal cancer: A systematic review and meta-analysis","authors":"","doi":"10.1016/j.jtemin.2024.100185","DOIUrl":"10.1016/j.jtemin.2024.100185","url":null,"abstract":"<div><h3>Introduction</h3><p>Among the increasing number of cancer cases, colorectal cancer (CRC) cases are rising globally. The association of zinc in the neoplastic process of CRC is a major research avenue, yet the published reports have not provided any definitive conclusion.</p></div><div><h3>Objectives</h3><p>We examined the association between serum zinc levels and CRC to test the potential of zinc dysregulation as a CRC susceptibility factor.</p></div><div><h3>Methods</h3><p>In this systemic review and meta-analysis, we extensively searched EBSCOhost, EMBASE, Cochrane Library, ProQuest, PubMed/MEDLINE, Scopus, and Web of Science as well as manual screening by subject experts for studies reporting serum/plasma/blood zinc levels in CRC patients and control subjects till 27th August 2023. Based on a random effect model, we estimated the mean difference in serum/plasma/blood zinc levels between CRC cases and control subjects. Subgroup differences and publication bias were also investigated, along with a critical appraisal of included studies.</p></div><div><h3>Results</h3><p>Eighteen studies with 8330 participants were included. The difference in serum zinc between CRC patients and control subjects was –5.01 µg/dl [95 % CI: −21.76 to 11.74; <em>p</em> = 0.56]. Omitting a highly influential outlier study, made this difference statistically significant at –13.28 µg/dl [95 % CI: −20.66 to -5.90, <em>p</em> &lt; 0.01]. The difference between study effects could not be explained by the difference in analytical methods for zinc assessment, or type of blood samples.</p></div><div><h3>Conclusion</h3><p>CRC patients had lower serum zinc levels. Some factors, such as different tumor grades of CRC, adenomas, and colonic polyps need to be further considered for a more conclusive association between serum zinc levels and risk for CRC.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000703/pdfft?md5=e6608dee92e8b769fb2eb94c1d85689b&pid=1-s2.0-S2773050624000703-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141963715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nano-CaO as a heterogeneous catalyst for biodiesel synthesis by transesterification of Jatropha oil 纳米氧化钙作为麻风树油酯交换反应合成生物柴油的异相催化剂
Pub Date : 2024-06-30 DOI: 10.1016/j.jtemin.2024.100183
Wisdom Chukwuemeke Ulakpa , Cyrus Aseibichin , Ohiri Augustine Chimezie , Ayodeji Arnold Olaseinde , Eyide Odeworitse , Erhinyodavwe Onoriode , Ijara Maryjane Adaeze

Background

This research employs response surface methodology, specifically Central Composite Design (CCD), to optimize the process parameters for the effective production of biodiesel. Jatropha oil was utilized as the raw material to minimize expenses. A nanocatalyst was utilized as a solid catalyst, developed from CaCO3 via waste snail shells, offering advantages such as recyclability and improved catalytic activity during a transesterification process. The developed nanocatalyst was analyzed using various techniques, including dynamic light scattering (DLS), scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) analysis, and Fourier-transform infrared (FTIR). The BET analysis revealed a surface area of 5.1m2/g and the Barrett-Joyner-Halenda (BJH) analysis provided insights into the pore volume and diameter of the synthesized nano-CaO, showing values of 0.002556 cc/g and 1.1 nm, respectively, indicating the presence of both microspores and active sites on the external surface of the nano-CaO catalyst. Biodiesel conversion was controlled by adjusting factors like the methanol to oil ratio, catalyst weight, reaction time, reaction temperature, and agitation speed. A quadratic model was established to explore the correlation between the independent variables and the biodiesel conversion rate. The results showed a maximum biodiesel conversion rate of 96.73% under the optimal conditions: methanol to oil ratio (6:1), catalyst weight (1.4 wt%), reaction time (60 min), reaction temperature (55 °C), and agitation speed (250 rpm). These parameters were determined through 32 experimental trials. The RSM technique yielded impressive results with a determined coefficient of determination (R2) of 0.9834, adjusted R2 of 0.8503, predicted R2 of 0.8309, and a coefficient of variance (CV) 0.75%. Based on the analysis of variance (ANOVA) findings, the model exhibits a high level of significance (p<0.0001), which is less than 0.05 and F- Value 29.71.The study aims to enhance the yield and efficiency of the transesterification process, thereby increasing the overall production of fatty acid methyl ester from Jatropha oil. This innovative approach efficiently generates biodiesel from renewable resources, in a manner that is both environmentally friendly and maximizes the effectiveness of the process parameters. The evaluation conform that the quality of the biodiesel met the standards set by ASTM D 6751 and EN 14214.

背景本研究采用响应面方法,特别是中央复合设计(CCD),优化工艺参数,以有效生产生物柴油。麻风树油被用作原料,以最大限度地降低成本。利用废弃蜗牛壳中的 CaCO3 制成的纳米催化剂作为固体催化剂,这种催化剂在酯交换过程中具有可回收性和更高催化活性等优点。研究人员使用多种技术对所开发的纳米催化剂进行了分析,包括动态光散射(DLS)、扫描电子显微镜(SEM)、布鲁诺-艾美特-泰勒(BET)分析和傅立叶变换红外(FTIR)。BET 分析显示其表面积为 5.1m2/g,而 Barrett-Joyner-Halenda (BJH) 分析则揭示了合成纳米氧化钙的孔隙体积和直径,其值分别为 0.002556 cc/g 和 1.1 nm,表明纳米氧化钙催化剂的外表面同时存在微孢子和活性位点。通过调整甲醇与油的比例、催化剂重量、反应时间、反应温度和搅拌速度等因素控制生物柴油的转化率。建立了一个二次模型来探讨自变量与生物柴油转化率之间的相关性。结果表明,在甲醇与油的比例(6:1)、催化剂重量(1.4 wt%)、反应时间(60 分钟)、反应温度(55 °C)和搅拌速度(250 rpm)等最佳条件下,生物柴油转化率最高可达 96.73%。这些参数是通过 32 次试验确定的。RSM 技术得出了令人印象深刻的结果,确定系数 (R2) 为 0.9834,调整 R2 为 0.8503,预测 R2 为 0.8309,方差系数 (CV) 为 0.75%。该研究旨在提高酯交换过程的产量和效率,从而提高麻风树油脂肪酸甲酯的总体产量。这种创新方法从可再生资源中高效生成生物柴油,既环保又最大限度地提高了工艺参数的有效性。评估结果表明,生物柴油的质量符合 ASTM D 6751 和 EN 14214 规定的标准。
{"title":"Nano-CaO as a heterogeneous catalyst for biodiesel synthesis by transesterification of Jatropha oil","authors":"Wisdom Chukwuemeke Ulakpa ,&nbsp;Cyrus Aseibichin ,&nbsp;Ohiri Augustine Chimezie ,&nbsp;Ayodeji Arnold Olaseinde ,&nbsp;Eyide Odeworitse ,&nbsp;Erhinyodavwe Onoriode ,&nbsp;Ijara Maryjane Adaeze","doi":"10.1016/j.jtemin.2024.100183","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100183","url":null,"abstract":"<div><h3>Background</h3><p>This research employs response surface methodology, specifically Central Composite Design (CCD), to optimize the process parameters for the effective production of biodiesel. Jatropha oil was utilized as the raw material to minimize expenses. A nanocatalyst was utilized as a solid catalyst, developed from CaCO<sub>3</sub> via waste snail shells, offering advantages such as recyclability and improved catalytic activity during a transesterification process. The developed nanocatalyst was analyzed using various techniques, including dynamic light scattering (DLS), scanning electron microscopy (SEM), Brunauer–Emmett–Teller (BET) analysis, and Fourier-transform infrared (FTIR). The BET analysis revealed a surface area of 5.1m<sup>2</sup>/g and the Barrett-Joyner-Halenda (BJH) analysis provided insights into the pore volume and diameter of the synthesized nano-CaO, showing values of 0.002556 cc/g and 1.1 nm, respectively, indicating the presence of both microspores and active sites on the external surface of the nano-CaO catalyst. Biodiesel conversion was controlled by adjusting factors like the methanol to oil ratio, catalyst weight, reaction time, reaction temperature, and agitation speed. A quadratic model was established to explore the correlation between the independent variables and the biodiesel conversion rate. The results showed a maximum biodiesel conversion rate of 96.73% under the optimal conditions: methanol to oil ratio (6:1), catalyst weight (1.4 wt%), reaction time (60 min), reaction temperature (55 °C), and agitation speed (250 rpm). These parameters were determined through 32 experimental trials. The RSM technique yielded impressive results with a determined coefficient of determination (R<sup>2</sup>) of 0.9834, adjusted R<sup>2</sup> of 0.8503, predicted R<sup>2</sup> of 0.8309, and a coefficient of variance (CV) 0.75%. Based on the analysis of variance (ANOVA) findings, the model exhibits a high level of significance (<em>p</em>&lt;0.0001), which is less than 0.05 and F- Value 29.71.The study aims to enhance the yield and efficiency of the transesterification process, thereby increasing the overall production of fatty acid methyl ester from Jatropha oil. This innovative approach efficiently generates biodiesel from renewable resources, in a manner that is both environmentally friendly and maximizes the effectiveness of the process parameters. The evaluation conform that the quality of the biodiesel met the standards set by ASTM D 6751 and EN 14214.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000685/pdfft?md5=4833565530de6c2838f980a87f5d217e&pid=1-s2.0-S2773050624000685-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141595907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety evaluation of human exposure to potentially toxic metals in the organs of sheep from southern Nigeria 对人类接触尼日利亚南部绵羊器官中潜在有毒金属的安全性评估
Pub Date : 2024-06-29 DOI: 10.1016/j.jtemin.2024.100184

Introduction

The concentrations and risks of metals (Cd, Pb, Cr, Ni, Cu, Co, Mn, Zn and Fe) in organs of sheep from Southern Nigeria were investigated in this study.

Methodology

A total of 105 sheep organs (kidney, liver and muscles) were collected from abattoirs in five widely distributed areas (Asaba, Benin, Onitsha, Sapele and Warri) in southern Nigeria. The organs were digested using a mixture of nitric and perchloric acids and thereafter the metal concentrations in the digested sample solutions were determined using an atomic absorption spectrophotometer.

Results

The mean concentrations of metals (mg kg−1) were as follows: Cd: 0.05–0.37, Pb 0.86 to 1.99, Cr: 2.20–3.03, Ni: 1.87–3.54, Cu: 17.4–24.3, Co: 1.45–4.30, Mn 192–410, Zn: 41.8–117 and Fe: 423–1068. The concentrations of the metals in the organs were in the order of Fe > Mn > Zn > Cu > Ni > Cr > Co > Pb > Cd while the ability of the sheep organs to accumulate the studied metals followed the order of liver > kidney > muscles. The estimated daily intake values suggested that except for Mn, the intake of metals from the ingestion of these sheep organs was below their respective PTDI. The hazard index and total cancer risk values show that there are no possible risks of non-cancer and cancer risks associated with the consumption of the sheep's organs.

Conclusion

Although there are no health risks associated with the metals in the sheep organs from southern Nigeria, there is, however, a need for continuous monitoring of contaminants in sheep and other animal organs.

引言 本研究调查了尼日利亚南部绵羊器官中金属(镉、铅、铬、镍、铜、钴、锰、锌和铁)的浓度和风险。方法 从尼日利亚南部分布广泛的五个地区(阿萨巴、贝宁、奥尼特沙、萨佩莱和瓦里)的屠宰场共收集了 105 个绵羊器官(肾脏、肝脏和肌肉)。使用硝酸和高氯酸混合物消化这些器官,然后使用原子吸收分光光度计测定消化样品溶液中的金属浓度:镉镉:0.05-0.37;铅:0.86-1.99;铬:2.20-3.03;镍:1.87-3.54;铜:17.4-24.3;钴:17.4-24.3;镍:17.4-24.3;铜:17.4-24.3:17.4-24.3,钴:1.45-4.30,锰:192-410,锌:41.8-117,铁:41.8-117:41.8-117,铁:423-1068。各器官中的金属浓度依次为:铁、锰、锌、铜、镍、铬、钴、铅、镉,而羊各器官对所研究金属的蓄积能力依次为:肝脏、肾脏、肌肉。估计的每日摄入量值表明,除锰外,从这些绵羊器官摄入的金属低于其各自的暂定每日可容忍摄入量。危害指数和总癌症风险值表明,食用绵羊内脏不会带来非癌症风险和癌症风险。结论尽管尼日利亚南部绵羊内脏中的金属不会带来健康风险,但仍有必要对绵羊和其他动物内脏中的污染物进行持续监测。
{"title":"Safety evaluation of human exposure to potentially toxic metals in the organs of sheep from southern Nigeria","authors":"","doi":"10.1016/j.jtemin.2024.100184","DOIUrl":"10.1016/j.jtemin.2024.100184","url":null,"abstract":"<div><h3>Introduction</h3><p>The concentrations and risks of metals (Cd, Pb, Cr, Ni, Cu, Co, Mn, Zn and Fe) in organs of sheep from Southern Nigeria were investigated in this study.</p></div><div><h3>Methodology</h3><p>A total of 105 sheep organs (kidney, liver and muscles) were collected from abattoirs in five widely distributed areas (Asaba, Benin, Onitsha, Sapele and Warri) in southern Nigeria. The organs were digested using a mixture of nitric and perchloric acids and thereafter the metal concentrations in the digested sample solutions were determined using an atomic absorption spectrophotometer.</p></div><div><h3>Results</h3><p>The mean concentrations of metals (mg kg<sup>−1</sup>) were as follows: Cd: 0.05–0.37, Pb 0.86 to 1.99, Cr: 2.20–3.03, Ni: 1.87–3.54, Cu: 17.4–24.3, Co: 1.45–4.30, Mn 192–410, Zn: 41.8–117 and Fe: 423–1068. The concentrations of the metals in the organs were in the order of Fe &gt; Mn &gt; Zn &gt; Cu &gt; Ni &gt; Cr &gt; Co &gt; Pb &gt; Cd while the ability of the sheep organs to accumulate the studied metals followed the order of liver &gt; kidney &gt; muscles. The estimated daily intake values suggested that except for Mn, the intake of metals from the ingestion of these sheep organs was below their respective PTDI. The hazard index and total cancer risk values show that there are no possible risks of non-cancer and cancer risks associated with the consumption of the sheep's organs.</p></div><div><h3>Conclusion</h3><p>Although there are no health risks associated with the metals in the sheep organs from southern Nigeria, there is, however, a need for continuous monitoring of contaminants in sheep and other animal organs.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000697/pdfft?md5=a01deada6d4230276becc4c794c52f30&pid=1-s2.0-S2773050624000697-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Assessment of the potential health risks associated with six trace elements in halieutic products from the Mauritanian Atlantic coast” [Journal of Trace Elements and Minerals 2C (2022) 100032] 毛里塔尼亚大西洋沿岸卤化产品中六种微量元素的潜在健康风险评估》[《微量元素和矿物质杂志》2C (2022) 100032]更正
Pub Date : 2024-06-27 DOI: 10.1016/j.jtemin.2024.100178
Hana Youssef Learoussy , Hasni Tfeil , Mohamed Salem El Mahmoud-Hamed , Aly Dartige , Mohamed Fakhaoui , Lotfi Aarab
{"title":"Corrigendum to “Assessment of the potential health risks associated with six trace elements in halieutic products from the Mauritanian Atlantic coast” [Journal of Trace Elements and Minerals 2C (2022) 100032]","authors":"Hana Youssef Learoussy ,&nbsp;Hasni Tfeil ,&nbsp;Mohamed Salem El Mahmoud-Hamed ,&nbsp;Aly Dartige ,&nbsp;Mohamed Fakhaoui ,&nbsp;Lotfi Aarab","doi":"10.1016/j.jtemin.2024.100178","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100178","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000636/pdfft?md5=9804c99a7997e40b05d565db71e12a5e&pid=1-s2.0-S2773050624000636-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “Chemometric analysis and risk assessment indices to evaluate water and sediment contamination of a tropical mangrove forest” [Journal of Trace Elements and Minerals 2C (2022) 100028] 评估热带红树林水和沉积物污染的化学计量分析和风险评估指数》[《微量元素和矿物质杂志》2C (2022) 100028]更正
Pub Date : 2024-06-22 DOI: 10.1016/j.jtemin.2024.100177
Parul Maurya , Rina Kumari , Rajesh Kumar Ranjan , Jigar Kumar B. Solanki
{"title":"Corrigendum to “Chemometric analysis and risk assessment indices to evaluate water and sediment contamination of a tropical mangrove forest” [Journal of Trace Elements and Minerals 2C (2022) 100028]","authors":"Parul Maurya ,&nbsp;Rina Kumari ,&nbsp;Rajesh Kumar Ranjan ,&nbsp;Jigar Kumar B. Solanki","doi":"10.1016/j.jtemin.2024.100177","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100177","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000624/pdfft?md5=70be54eed206557ab020d70e374ee0f2&pid=1-s2.0-S2773050624000624-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential cancer risks of metals/metalloids and radionuclides through the intake of food crops grown around the mining area 通过摄入矿区周围种植的粮食作物,金属/类金属和放射性核素的潜在致癌风险
Pub Date : 2024-06-20 DOI: 10.1016/j.jtemin.2024.100181
Hamza Badamasi , Umar Faruk Hassan , Harami Malgwi Adamu , Nasirudeen Mohammed Baba , Muhammad Salman Khan , Mushtaq Ahmad Khan

Background

Food crop consumption is one of the primary routes through which the environment is polluted with radionuclides, metals, and metalloids. In recent years, the negative impacts of metals, metalloids, and radionuclides on crop quality via the food-human system have jeopardized both human health and food security. Because some metals, metalloids, and radionuclides are persistent and non-biodegradable, they build up in the human body's essential organs, causing a variety of serious health issues, including cancer. It is therefore absolutely essential to evaluate the potential cancer risks of radionuclides as well as metals and metalloids in the food crops consumed in the study area to avoid negative health consequences.

Objective

The aim of this study was to assess the potential cancer risks of metals and metalloids (As, Cd, Cr, and Pb) and Radionuclides (U-238, Th-232, and K-40) via consumption of food crops cultivated around the Riruwai mining area, northeastern Nigeria.

Methodology

Thirty-three (33) food crops (15 vegetables and 18 cereal crops) were collected directly from the farmlands in the study area. The concentrations of radionuclides, metals, and metalloid in each food crop were assessed using a microwave-plasma atomic emission spectrometry (MP-AES) and a high-purity germanium (HPGe) gamma-ray spectrometer, respectively. The measured concentrations of radionuclides, metals, and metalloid were used to calculate their lifetime cancer risks (LTCRs).

Results

The findings of the study revealed that the concentrations of As, Cd, Cr, and Pb in all the investigated food crops were above the threshold limits, while lower activity concentrations in all the investigated food crops below the world average standard were observed in U-238, Th-232, and K-40. LTCRs of all the individual metal and metalloid as well as radionuclide in each food crop were determined to be below the global threshold limits, indicating no likelihood of cancer risk from consuming the food crops. However, it was discovered that the total cumulative LTCRs of all the metals and metalloid in all food crops combined were 2.51E-04, which was over twofold the acceptable limit of 1.00E-04

Conclusion

The individual metal, metalloid, and radionuclide LTCRs in each food crop were found to be below global threshold limits, indicating no cancer risk from consumption. However, the cumulative LTCRs of all the metals and metalloid in all food crops were found to exceed the acceptable level, which requires proper monitoring and government intervention. Cancer risk is influenced by factors beyond food consumption, such as alcohol consumption, heredity, and air pollution, so multidimensional studies are needed before making a final decision on cancer risks in the study area.

背景粮食作物消费是放射性核素、金属和类金属污染环境的主要途径之一。近年来,金属、类金属和放射性核素通过食物-人类系统对作物质量产生的负面影响已经危及人类健康和粮食安全。由于某些金属、类金属和放射性核素具有持久性和不可生物降解性,它们会在人体的重要器官中积聚,导致各种严重的健康问题,包括癌症。因此,绝对有必要对研究地区食用的粮食作物中放射性核素以及金属和类金属的潜在致癌风险进行评估,以避免对健康造成负面影响。本研究旨在评估尼日利亚东北部 Riruwai 矿区周围种植的粮食作物中金属和类金属(砷、镉、铬和铅)以及放射性核素(铀 238、钍 232 和 K-40)的潜在致癌风险。分别使用微波等离子体原子发射光谱仪 (MP-AES) 和高纯锗(HPGe)伽马射线光谱仪评估了每种粮食作物中放射性核素、金属和类金属的浓度。研究结果显示,所有调查的粮食作物中的砷、镉、铬和铅的浓度都高于阈值限值,而所有调查的粮食作物中铀 238、钍 232 和 K-40 的放射性活度浓度都低于世界平均标准。经测定,每种粮食作物中所有金属和类金属以及放射性核素的低放射性活度均低于全球阈值限值,表明食用这些粮食作物不会有致癌风险。结 论 各 种 农 作 物 的 个 别 金 属 、 类 金 属 及 放 射 性 核 素 的 长 期 致 癌 比 率 均 低 于 全 球 的 阈 限 , 显 示 食 用 农 作 物 不 会 引 致 癌 症 风 险 。然而,所有粮食作物中所有金属和类金属的累积长效热稳定性超过了可接受的水平,这就需要适当的监测和政府干预。癌症风险受食物消费以外因素的影响,如饮酒、遗传和空气污染,因此在对研究地区的癌症风险做出最终决定之前,需要进行多方面的研究。
{"title":"Potential cancer risks of metals/metalloids and radionuclides through the intake of food crops grown around the mining area","authors":"Hamza Badamasi ,&nbsp;Umar Faruk Hassan ,&nbsp;Harami Malgwi Adamu ,&nbsp;Nasirudeen Mohammed Baba ,&nbsp;Muhammad Salman Khan ,&nbsp;Mushtaq Ahmad Khan","doi":"10.1016/j.jtemin.2024.100181","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100181","url":null,"abstract":"<div><h3>Background</h3><p>Food crop consumption is one of the primary routes through which the environment is polluted with radionuclides, metals, and metalloids. In recent years, the negative impacts of metals, metalloids, and radionuclides on crop quality via the food-human system have jeopardized both human health and food security. Because some metals, metalloids, and radionuclides are persistent and non-biodegradable, they build up in the human body's essential organs, causing a variety of serious health issues, including cancer. It is therefore absolutely essential to evaluate the potential cancer risks of radionuclides as well as metals and metalloids in the food crops consumed in the study area to avoid negative health consequences.</p></div><div><h3>Objective</h3><p>The aim of this study was to assess the potential cancer risks of metals and metalloids (As, Cd, Cr, and Pb) and Radionuclides (U-238, Th-232, and K-40) via consumption of food crops cultivated around the Riruwai mining area, northeastern Nigeria.</p></div><div><h3>Methodology</h3><p>Thirty-three (33) food crops (15 vegetables and 18 cereal crops) were collected directly from the farmlands in the study area. The concentrations of radionuclides, metals, and metalloid in each food crop were assessed using a microwave-plasma atomic emission spectrometry (MP-AES) and a high-purity germanium (HPGe) gamma-ray spectrometer, respectively. The measured concentrations of radionuclides, metals, and metalloid were used to calculate their lifetime cancer risks (<em>LTCRs</em>).</p></div><div><h3>Results</h3><p>The findings of the study revealed that the concentrations of As, Cd, Cr, and Pb in all the investigated food crops were above the threshold limits, while lower activity concentrations in all the investigated food crops below the world average standard were observed in U-238, Th-232, and K-40. <em>LTCRs</em> of all the individual metal and metalloid as well as radionuclide in each food crop were determined to be below the global threshold limits, indicating no likelihood of cancer risk from consuming the food crops. However, it was discovered that the total cumulative <em>LTCRs</em> of all the metals and metalloid in all food crops combined were 2.51E-04, which was over twofold the acceptable limit of 1.00E-04</p></div><div><h3>Conclusion</h3><p>The individual metal, metalloid, and radionuclide <em>LTCRs</em> in each food crop were found to be below global threshold limits, indicating no cancer risk from consumption. However, the cumulative <em>LTCRs</em> of all the metals and metalloid in all food crops were found to exceed the acceptable level, which requires proper monitoring and government intervention. Cancer risk is influenced by factors beyond food consumption, such as alcohol consumption, heredity, and air pollution, so multidimensional studies are needed before making a final decision on cancer risks in the study area.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000661/pdfft?md5=197960afc8bddccdc61b4d5bdde8ab3b&pid=1-s2.0-S2773050624000661-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial for the Virtual Special Issue (VSI) “Seafood Contamination by metals and metalloids” 为虚拟特刊(VSI)"金属和类金属对海产品的污染 "撰写编辑文章
Pub Date : 2024-06-20 DOI: 10.1016/j.jtemin.2024.100182
Rachel Ann Hauser-Davis
{"title":"Editorial for the Virtual Special Issue (VSI) “Seafood Contamination by metals and metalloids”","authors":"Rachel Ann Hauser-Davis","doi":"10.1016/j.jtemin.2024.100182","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100182","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000673/pdfft?md5=6c2bd9f786469304c891d823c4e847a0&pid=1-s2.0-S2773050624000673-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of trace elements and minerals
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1