{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100273"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146467691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100276"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146467690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100271"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146467692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100280"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146467687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100277"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146467683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100274"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146467686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study presents the green synthesis and comprehensive biological evaluation of selenium nanoparticles (Se-NPs) derived from Saraca asoca leaf extract.
Methods
The biosynthesized Se-NPs were characterized using UV – Visible spectroscopy, Fourier - transfer infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM), confirming their nanoscale morphology and phytochemical capping. The antioxidant potential of Se-NPs was assessed via DPPH and ABTS radical scavenging assays.
Results
demonstrating significant activity with 73 ± 3.65% and 90 ± 4.5% inhibition, respectively, at 100 µg/mL. Antigout efficacy was evaluated through uric acid degradation and xanthine oxidase inhibition (XOI), revealing dose- dependent activity with 62 ± 1.86% UA degradation at 19 mg/mL and 76% XOI at 200 µg/mL. Furthermore, Se-NPs exhibited notable anticoagulant and thrombolytic effects in mammalian blood, indicating their potential to modulates haemostatic pathways.
Conclusion
Collectively, these findings underscore the multifunctional therapeutic properties of Saraca asoca -mediated Se-NPs, positioning them as promising candidates for future biomedical application targeting oxidant stress, hyperuricemia, thrombotic disorders.
{"title":"Green-Synthesized selenium nanoparticles from Saraca asoca leaves: A multifunctional evaluation of antioxidant, anticoagulant, antigout and thrombolytic activities","authors":"Suhana Malik , Prachi Tiwari , Anuradha Singhaniya , Chandrababu Rejeeth","doi":"10.1016/j.jtemin.2025.100277","DOIUrl":"10.1016/j.jtemin.2025.100277","url":null,"abstract":"<div><h3>Background</h3><div>This study presents the green synthesis and comprehensive biological evaluation of selenium nanoparticles (Se-NPs) derived from <em>Saraca asoca</em> leaf extract.</div></div><div><h3>Methods</h3><div>The biosynthesized Se-NPs were characterized using UV – Visible spectroscopy, Fourier - transfer infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM), confirming their nanoscale morphology and phytochemical capping. The antioxidant potential of Se-NPs was assessed via DPPH and ABTS radical scavenging assays.</div></div><div><h3>Results</h3><div>demonstrating significant activity with 73 ± 3.65% and 90 ± 4.5% inhibition, respectively, at 100 µg/mL. Antigout efficacy was evaluated through uric acid degradation and xanthine oxidase inhibition (XOI), revealing dose- dependent activity with 62 ± 1.86% UA degradation at 19 mg/mL and 76% XOI at 200 µg/mL. Furthermore, Se-NPs exhibited notable anticoagulant and thrombolytic effects in mammalian blood, indicating their potential to modulates haemostatic pathways.</div></div><div><h3>Conclusion</h3><div>Collectively, these findings underscore the multifunctional therapeutic properties of <em>Saraca asoca</em> -mediated Se-NPs, positioning them as promising candidates for future biomedical application targeting oxidant stress, hyperuricemia, thrombotic disorders.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100277"},"PeriodicalIF":0.0,"publicationDate":"2025-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-28DOI: 10.1016/j.jtemin.2025.100276
Misbah Rani , Zainul Abideen , Neelma Munir , Maria Hasnain , Mohammad Mehdizadeh , Muhammed Qasim , Emanuele Radicetti
Background
Soil degradation, caused by salinity, nutrient depletion, and trace metal pollutants, is a major problem for agricultural productivity. Organic amendments, such as biochar, have shown potential to improve soil health, water retention, and nutrient availability. However, biochar-based blended amendments, such as biochar compost mixture and composted biochar, may offer greater benefits even under harsh soil environments.
Objectives
This systematic review evaluates the limitations and advantages of biochar, compost, and biochar-compost mixtures in restoring degraded and polluted soils. The review assesses their roles in improving soil fertility, nutrient availability, microbial activity, and key physiochemical properties relevant to sustainable agriculture.
Methods
Following PRISMA guidelines, we systematically searched major scientific databases and screened studies based on predefined inclusion and exclusion criteria. Eligible studies included laboratory, greenhouse, and field experiments assessing soil restoration outcomes using biochar-based amendments.
Key findings
Biochar applications enhanced biomass production, CO2 capture, soil quality, and immobilization of inorganic ions and organic waste material due to promising properties like advanced cation exchange capacity, high permeability, and large surface area. Biochar-compost further improved nutrient availability, biomass uptake, water retention, carbon sequestration, and plant physiological responses under stress. Composted biochar offered more sustained and long-lasting improvements in soil quality and plant productivity under salinity stress, thus solving multiple biochar-associated challenges, although further long-term field evidence is still needed.
Broader implications
Overall, biochar and biochar-compost represent promising tools for soil restoration, pollutant remediation, and crop productivity. Although their benefits are widely reported, variability in outcomes and gaps in long-term evidence underscore the importance of optimizing application strategies for different soil systems.
{"title":"Enhancing soil fertility, nutrient recovery and carbon sequestration: the role of biochar, composted biochar, and biochar-compost mixtures in sustainable agriculture","authors":"Misbah Rani , Zainul Abideen , Neelma Munir , Maria Hasnain , Mohammad Mehdizadeh , Muhammed Qasim , Emanuele Radicetti","doi":"10.1016/j.jtemin.2025.100276","DOIUrl":"10.1016/j.jtemin.2025.100276","url":null,"abstract":"<div><h3>Background</h3><div>Soil degradation, caused by salinity, nutrient depletion, and trace metal pollutants, is a major problem for agricultural productivity. Organic amendments, such as biochar, have shown potential to improve soil health, water retention, and nutrient availability. However, biochar-based blended amendments, such as biochar compost mixture and composted biochar, may offer greater benefits even under harsh soil environments.</div></div><div><h3>Objectives</h3><div>This systematic review evaluates the limitations and advantages of biochar, compost, and biochar-compost mixtures in restoring degraded and polluted soils. The review assesses their roles in improving soil fertility, nutrient availability, microbial activity, and key physiochemical properties relevant to sustainable agriculture.</div></div><div><h3>Methods</h3><div>Following PRISMA guidelines, we systematically searched major scientific databases and screened studies based on predefined inclusion and exclusion criteria. Eligible studies included laboratory, greenhouse, and field experiments assessing soil restoration outcomes using biochar-based amendments.</div></div><div><h3>Key findings</h3><div>Biochar applications enhanced biomass production, CO<sub>2</sub> capture, soil quality, and immobilization of inorganic ions and organic waste material due to promising properties like advanced cation exchange capacity, high permeability, and large surface area. Biochar-compost further improved nutrient availability, biomass uptake, water retention, carbon sequestration, and plant physiological responses under stress. Composted biochar offered more sustained and long-lasting improvements in soil quality and plant productivity under salinity stress, thus solving multiple biochar-associated challenges, although further long-term field evidence is still needed.</div></div><div><h3>Broader implications</h3><div>Overall, biochar and biochar-compost represent promising tools for soil restoration, pollutant remediation, and crop productivity. Although their benefits are widely reported, variability in outcomes and gaps in long-term evidence underscore the importance of optimizing application strategies for different soil systems.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100276"},"PeriodicalIF":0.0,"publicationDate":"2025-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-25DOI: 10.1016/j.jtemin.2025.100275
Fernanda Patti Nakamoto, Kauana Multini de Almeida, Larissa Canton Gonçalves, Marcus V.L. dos Santos Quaresma
Aim and background
Female athletes have been considered a risk group for non-anemic iron deficiency (NAID) and iron deficiency anemia (IDA) given iron loss situations (i.e., excessive blood lost during a menstrual cycle, eccentric muscle contraction, and sweating). Iron supplementation should be a strategy to increase both iron levels and physical exercise performance. To verify the effect of iron supplementation on the exercise performance of women with NAID or IDA, a systematic review and meta-analysis was conducted (CRD42021245452).
Materials and methods
Inclusion criteria comprised randomized or non-randomized clinical trials with a control group that determined the effect of iron supplementation associated with endurance exercise on women’s exercise performance. A search of the MEDLINE/PubMed, LILACS, SciELO, and Scopus databases was performed in February 2025 including all articles.
Results
A total of 2122 studies were initially identified. Following exclusions, 15 studies with a total of 380 participants were included. Iron supplementation did not improve exercise performance assessed during time-to-exhaustion (TTE; MD: 0.76 min; 95% CI: -0.13; 1.65; p = 0.067) or time trial (TT; MD: -1.78 min; 95% CI: -3.88; 0.333 min; p = 0.059) protocols. Still, by combining TTE and TT studies in the same analysis, we observed a non-significant effect on exercise performance (SMD: 0.97; 95% CI: -0.49 to 2.44; p = 0.139). Moreover, although iron supplementation led to consistent improvements in hemoglobin and serum ferritin levels, its effects on cardiorespiratory fitness and exercise performance were mixed. We observed a moderate and statistically significant improvement in V̇O₂max or V̇O₂peak (SMD: 0.70; 95% CI: 0.08 to 1.31; p = 0.030). However, this effect was no longer statistically significant when studies involving women with anemia were excluded (SMD: 0.61; 95% CI: -0.05 to 1.27; p = 0.068), suggesting that the observed improvement in cardiorespiratory fitness may be primarily driven by this subgroup. In contrast, no significant effects were found on exercise performance outcomes such as TTE or TT performance.
Conclusion
Although iron supplementation led to improvements in hemoglobin and serum ferritin levels, its effects on exercise performance and cardiorespiratory fitness were limited.
{"title":"Effect of iron supplementation on exercise performance of women with non-anemic iron deficiency or iron deficiency anemia - a systematic review and meta-analysis","authors":"Fernanda Patti Nakamoto, Kauana Multini de Almeida, Larissa Canton Gonçalves, Marcus V.L. dos Santos Quaresma","doi":"10.1016/j.jtemin.2025.100275","DOIUrl":"10.1016/j.jtemin.2025.100275","url":null,"abstract":"<div><h3>Aim and background</h3><div>Female athletes have been considered a risk group for non-anemic iron deficiency (NAID) and iron deficiency anemia (IDA) given iron loss situations (i.e., excessive blood lost during a menstrual cycle, eccentric muscle contraction, and sweating). Iron supplementation should be a strategy to increase both iron levels and physical exercise performance. To verify the effect of iron supplementation on the exercise performance of women with NAID or IDA, a systematic review and meta-analysis was conducted (CRD42021245452).</div></div><div><h3>Materials and methods</h3><div>Inclusion criteria comprised randomized or non-randomized clinical trials with a control group that determined the effect of iron supplementation associated with endurance exercise on women’s exercise performance. A search of the MEDLINE/PubMed, LILACS, SciELO, and Scopus databases was performed in February 2025 including all articles.</div></div><div><h3>Results</h3><div>A total of 2122 studies were initially identified. Following exclusions, 15 studies with a total of 380 participants were included. Iron supplementation did not improve exercise performance assessed during time-to-exhaustion (TTE; MD: 0.76 min; 95% CI: -0.13; 1.65; <em>p</em> = 0.067) or time trial (TT; MD: -1.78 min; 95% CI: -3.88; 0.333 min; <em>p</em> = 0.059) protocols. Still, by combining TTE and TT studies in the same analysis, we observed a non-significant effect on exercise performance (SMD: 0.97; 95% CI: -0.49 to 2.44; <em>p</em> = 0.139). Moreover, although iron supplementation led to consistent improvements in hemoglobin and serum ferritin levels, its effects on cardiorespiratory fitness and exercise performance were mixed. We observed a moderate and statistically significant improvement in V̇O₂max or V̇O₂peak (SMD: 0.70; 95% CI: 0.08 to 1.31; <em>p</em> = 0.030). However, this effect was no longer statistically significant when studies involving women with anemia were excluded (SMD: 0.61; 95% CI: -0.05 to 1.27; <em>p</em> = 0.068), suggesting that the observed improvement in cardiorespiratory fitness may be primarily driven by this subgroup. In contrast, no significant effects were found on exercise performance outcomes such as TTE or TT performance.</div></div><div><h3>Conclusion</h3><div>Although iron supplementation led to improvements in hemoglobin and serum ferritin levels, its effects on exercise performance and cardiorespiratory fitness were limited.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100275"},"PeriodicalIF":0.0,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-21DOI: 10.1016/j.jtemin.2025.100274
Aduema Wadioni , Olusegun G. Adebayo , Adebimpe V. Masanwoola , Joseph Chimezie
Background: Exposures to transition metals such as copper have been investigated in Parkinson’s disease (PD) patients’ brain with the concentrations higher comparative to the non-diseased. However, the mechanistic approach in PD remains largely unexplored.Objectives This study aims to investigate the Zingiber officinale methanol extract (MEZO) neuroprotective effect in mice striatal and nigral neurons after exposure to copper intoxication. Methods: A total of 40 mice (n = 8 mice/group) were treated orally with distilled water (10 mL kg-1; group 1), copper sulfate (CuSO4, 20 mg kg-1; group 2), MEZO (50 and 100 mg kg-1; group 3 and 4), and vitamin C (100 mg kg-1; group 5) repeatedly for 28 days. The mice in group 3 – 5 were pre-treated with CuSO4, followed 1 hour later by MEZO and Vitamin C treatment. Locomotor and neuromuscular performances were assessed using open field, negative geotaxis and tail suspension test, respectively. After termination, markers of oxidative stress and inflammation, neuronal transmission, and histoarchitectural changes were evaluated in the brain tissues. Results: The exposure to CuSO4 treatment induced significant reduction in locomotor and neuromuscular competence but was improved following the administration of MEZO. Oral exposure to CuSO4 increased striatal pro-oxidants (malondialdehyde and nitrite), inflammatory mediators (MPO, TNF-α, and IL-6), and α-synuclein levels; and decreased endogenous antioxidant enzymes (glutathione and catalase), anti-inflammatory cytokine (IL-10), dopamine, acetylcholinesterase (AChE) and brain derived neurotophic factor (BDNF) levels in the striatum. However, the administration of MEZO decreased pro-oxidants, inflammatory mediators, and α-synuclein levels; and increased the endogenous antioxidant enzymes, anti-inflammatory cytokine, dopamine, AChE and BDNF levels in the mice striatum in a dose-related manner. Additionally, the administration of MEZO abated the loss of the nigrostriatal neurons as well as the structural integrity after CuSO4 lesioning. Conclusion: The study suggests that MEZO could be used as a pharmacotherapy in the management and treatment of PD pathophysiology following exposure to CuSO4 intoxication.
{"title":"Neuroprotective potential of Zingiber officinale methanol extract in copper sulfate-induced nigrostriatal neurodegeneration in mice","authors":"Aduema Wadioni , Olusegun G. Adebayo , Adebimpe V. Masanwoola , Joseph Chimezie","doi":"10.1016/j.jtemin.2025.100274","DOIUrl":"10.1016/j.jtemin.2025.100274","url":null,"abstract":"<div><div><strong>Background:</strong> Exposures to transition metals such as copper have been investigated in Parkinson’s disease (PD) patients’ brain with the concentrations higher comparative to the non-diseased. However, the mechanistic approach in PD remains largely unexplored.<strong>Objectives</strong> This study aims to investigate the <em>Zingiber officinale</em> methanol extract (MEZO) neuroprotective effect in mice striatal and nigral neurons after exposure to copper intoxication. <strong>Methods:</strong> A total of 40 mice (n = 8 mice/group) were treated orally with distilled water (10 mL kg<sup>-1</sup>; group 1), copper sulfate (CuSO<sub>4</sub>, 20 mg kg<sup>-1</sup>; group 2), MEZO (50 and 100 mg kg<sup>-1</sup>; group 3 and 4), and vitamin C (100 mg kg<sup>-1</sup>; group 5) repeatedly for 28 days. The mice in group 3 – 5 were pre-treated with CuSO<sub>4</sub>, followed 1 hour later by MEZO and Vitamin C treatment. Locomotor and neuromuscular performances were assessed using open field, negative geotaxis and tail suspension test, respectively. After termination, markers of oxidative stress and inflammation, neuronal transmission, and histoarchitectural changes were evaluated in the brain tissues. <strong>Results:</strong> The exposure to CuSO<sub>4</sub> treatment induced significant reduction in locomotor and neuromuscular competence but was improved following the administration of MEZO. Oral exposure to CuSO<sub>4</sub> increased striatal pro-oxidants (malondialdehyde and nitrite), inflammatory mediators (MPO, TNF-α, and IL-6), and α-synuclein levels; and decreased endogenous antioxidant enzymes (glutathione and catalase), anti-inflammatory cytokine (IL-10), dopamine, acetylcholinesterase (AChE) and brain derived neurotophic factor (BDNF) levels in the striatum. However, the administration of MEZO decreased pro-oxidants, inflammatory mediators, and α-synuclein levels; and increased the endogenous antioxidant enzymes, anti-inflammatory cytokine, dopamine, AChE and BDNF levels in the mice striatum in a dose-related manner. Additionally, the administration of MEZO abated the loss of the nigrostriatal neurons as well as the structural integrity after CuSO<sub>4</sub> lesioning. <strong>Conclusion:</strong> The study suggests that MEZO could be used as a pharmacotherapy in the management and treatment of PD pathophysiology following exposure to CuSO<sub>4</sub> intoxication.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"15 ","pages":"Article 100274"},"PeriodicalIF":0.0,"publicationDate":"2025-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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