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Revue francophone des laboratoires : RFL最新文献

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Brève : Où en est le projet de Centre national de ressources sur la cérébrolésion ? Brief: 建立国家脑瘫资源中心的项目已进行到什么阶段?
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00247-8
Jean-Marie Manus
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引用次数: 0
QCM : Évaluez-vous ! MCQs: 测试你自己!
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00264-8
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引用次数: 0
Hémochromatose : importance du dépistage en famille 血色素沉着病:家庭筛查的重要性
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00249-1
Jean-Marie Manus
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引用次数: 0
Oncologie : avancées sur le rétinoblastome pédiatrique 肿瘤学:小儿视网膜母细胞瘤的研究进展
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00257-0
Jean-Marie Manus
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引用次数: 0
Essai du lixisénatide dans la maladie de Parkinson précoce 利血那肽治疗早期帕金森病试验
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00241-7
Jean-Marie Manus
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引用次数: 0
Pharmacologie des médicaments de la douleur, des pathologies inflammatoires, immunitaires et rhumatismales et de l’anesthésie 治疗疼痛、炎症、免疫和风湿病以及麻醉的药物药理学
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00250-8
Jean-Marie Manus
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引用次数: 0
À quoi sert un biologiste aujourd’hui ? 今天,生物学家的目的是什么?
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00260-0
Christophe Martinaud
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引用次数: 0
Hormone GDF15 et nausées de la grossesse GDF15 激素与妊娠恶心
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00237-5
Jean-Marie Manus
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引用次数: 0
Transfusion massive en traumatologie 创伤中的大量输血
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00262-4
Vanina Corominas

Résumé

La prise en charge des victimes polytraumatisées est un défi majeur de santé publique. En France, les accidents de la route sont la quatrième cause de décès et les polytraumatismes restent le premier facteur d’années de vie perdues. Leur prise en charge est largement basée sur la transfusion sanguine, ciblant la coagulopathie aiguë du traumatisé. Les recommandations préconisent l’utilisation de concentrés de globules rouges, de plasma thérapeutique et de concentrés de plaquettes lors de transfusions massives. Les protocoles de transfusion massive visent à réduire les délais et à améliorer l’efficacité de la prise en charge. Les scores cliniques et les critères biologiques, dont la viscoélastométrie, aident à anticiper et à adapter les besoins transfusionnels. Les protocoles de transfusion massive, largement utilisés, présentent des variations dans leur contenu, leur ratio et leurs critères de déclenchement. Leur utilisation s’étend à d’autres indications que le traumatisme mais des défis subsistent en termes d’organisation, de composition des lots de transfusion et de gestion des gaspillages.

Abstract

Polytrauma is a major public health challenge. In France, road accidents rank fourth among causes of death, and polytraumas are the leading cause of years of life lost. Management is largely based on blood transfusion, targeting acute traumatic coagulopathy. Recommendations advocate the use of packed red blood cells, therapeutic plasma, and platelet concentrates during massive transfusions. Massive Transfusion Protocols aim to reduce delays and enhance efficiency in management. Clinical scores and biological criteria, such as viscoelastic tests, help anticipate transfusion needs. Although widely used, massive transfusion protocols exhibit variations in content, ratios, and triggering criteria. Their application extends beyond trauma, posing challenges in terms of organization, transfusion pack composition, and waste management.

摘要护理多发性创伤患者是一项重大的公共卫生挑战。在法国,交通事故是导致死亡的第四大原因,而多发性创伤仍然是导致生命损失的主要原因。他们的治疗主要以输血为基础,针对的是创伤患者的急性凝血功能障碍。建议在大量输血时使用包装红细胞、治疗性血浆和包装血小板。大量输血方案旨在减少延误,提高管理效率。临床评分和生物学标准(包括粘弹性测定)有助于预测和调整输血需求。大规模输血方案已被广泛应用,其内容、比例和触发标准各不相同。除创伤外,大规模输血还被用于其他适应症,但在组织、输血批次组成和废物管理方面仍存在挑战。在法国,交通事故在死亡原因中排名第四,而多发性创伤则是造成生命损失的主要原因。治疗主要以输血为基础,针对急性创伤性凝血病。建议主张在大量输血时使用包装红细胞、治疗性血浆和浓缩血小板。大量输血协议旨在减少延误并提高管理效率。临床评分和生物学标准(如粘弹性测试)有助于预测输血需求。虽然大量输血协议被广泛使用,但其内容、比例和触发标准各不相同。其应用范围超出了创伤领域,在组织、输血包组成和废物管理方面提出了挑战。
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引用次数: 0
Covid-19, peut-on se faire vacciner plus de 200 fois sans conséquences ? Covid-19,你能接种 200 多次疫苗而不产生任何后果吗?
Pub Date : 2024-07-01 DOI: 10.1016/S1773-035X(24)00258-2
Jean-Marie Manus
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引用次数: 0
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Revue francophone des laboratoires : RFL
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