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Unity quantum yield of InP/ZnSe/ZnS quantum dots enabled by Zn halide-derived hybrid shelling approach 通过卤化锌衍生混合加壳方法实现 InP/ZnSe/ZnS 量子点的统一量子产率
Pub Date : 2024-07-17 DOI: 10.20517/ss.2024.19
Dae‐Yeon Jo, Hyun‐Min Kim, Goo Min Park, Donghyeok Shin, Yuri Kim, Yang-Hee Kim, Chae Woo Ryu, Heesun Yang
Environment-benign indium phosphide (InP) quantum dots (QDs) show great promise as visible emitters for next-generation display applications, where bright and narrow emissivity of QDs should be required toward high-efficiency, high-color reproducibility. The photoluminescence (PL) performance of InP QDs has been consistently, markedly improved, particularly owing to the exquisite synthetic control over core size homogeneity and core/shell heterostructural variation. To date, synthesis of most high-quality InP QDs has been implemented by using zinc (Zn) carboxylate as a shell precursor that unavoidably entails the formation of surface oxide on InP core. Herein, we demonstrate synthesis of superbly bright, color-pure green InP/ZnSe/ZnS QDs by exploring an innovative hybrid Zn shelling approach, where Zn halide (ZnX2, X = Cl, Br, I) and Zn oleate are co-used as shell precursors. In the hybrid Zn shelling process, the type of ZnX2 is found to affect the growth outcomes of ZnSe inner shell and consequent optical properties of the resulting heterostructured InP QDs. Enabled by not only the near-complete removal of the oxide layer on InP core surface through the hybrid Zn shelling process but the controlled growth rate of ZnSe inner shell, green InP/ZnSe/ZnS QDs achieve a record quantum yield (QY) up to unity along with a highly sharp linewidth of 32 nm upon growth of an optimal ZnSe shell thickness. This work affords an effective means to synthesize high-quality heterostructured InP QDs with superb emissive properties.
环境无害的磷化铟(InP)量子点(QDs)作为下一代显示器应用的可见光发射器大有可为。InP QDs 的光致发光(PL)性能得到了持续、显著的改善,这主要归功于对核尺寸均匀性和核/壳异质结构变化的精细合成控制。迄今为止,大多数高质量 InP QDs 的合成都是使用羧酸锌(Zn)作为壳前驱体,这不可避免地会在 InP 内核上形成表面氧化物。在这里,我们通过探索一种创新的混合锌脱壳方法,即卤化锌(ZnX2,X = Cl、Br、I)和油酸锌共同用作壳前驱体,展示了高亮度、色纯绿色 InP/ZnSe/ZnS QDs 的合成。在混合锌脱壳过程中,发现 ZnX2 的类型会影响 ZnSe 内壳的生长结果以及由此产生的异质结构 InP QD 的光学特性。绿色 InP/ZnSe/ZnS QD 不仅能通过混合 Zn 加壳工艺近乎完全去除 InP 内核表面的氧化层,还能控制 ZnSe 内壳的生长速度。这项研究为合成具有卓越发射特性的高质量异质结构 InP QD 提供了一种有效方法。
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引用次数: 0
Recent advances in laser-induced-graphene-based soft skin electronics for intelligent healthcare 激光诱导石墨烯基软皮肤电子技术在智能医疗领域的最新进展
Pub Date : 2024-07-09 DOI: 10.20517/ss.2024.20
Zhiqiang Ma, B. L. Khoo
Skin is a rich source of invaluable information for healthcare management and disease diagnostics. The integration of soft skin electronics enables precise and timely capture of these cues at the skin interface. Leveraging attributes such as lightweight design, compact size, high integration, biocompatibility, and enhanced comfort, these technologies hold significant promise for advancing various applications. However, the fabrication process for most existing soft skin electronics typically requires expensive platforms and clean-room environments, potentially inflating production costs. In recent years, the emergence of laser-induced-graphene (LIG) has presented a practical solution for developing soft skin electronics that are both cost-effective and high-performing. This advancement paves the way for the widespread adoption of intelligent healthcare technologies. Here, we comprehensively review recent studies focusing on LIG-based soft skin electronics (LIGS2E) for intelligent healthcare applications. We first outline the preparation methodologies, fundamental properties of LIG, and standard regulation strategies employed in developing soft skin electronics. Subsequently, we present an overview of various LIGS2E designs and their diverse applications in intelligent healthcare. These applications encompass biophysical and biochemical sensors, bio-actuators, and power supply systems. Finally, we deliberate on the potential challenges associated with the practical implementation of LIGS2E in healthcare settings and offer insights into future directions for research and development. By elucidating the capabilities and limitations of LIGS2E, this review aims to contribute to advancing intelligent healthcare technologies.
皮肤是医疗保健管理和疾病诊断的宝贵信息的丰富来源。集成软皮肤电子元件可在皮肤界面精确、及时地捕捉这些线索。这些技术具有设计轻巧、体积小巧、集成度高、生物相容性好和舒适度高的特点,在推动各种应用方面大有可为。然而,大多数现有软皮肤电子器件的制造工艺通常需要昂贵的平台和洁净室环境,这可能会抬高生产成本。近年来,激光诱导石墨烯(LIG)的出现为开发具有成本效益和高性能的软皮肤电子器件提供了一种实用的解决方案。这一进步为智能医疗保健技术的广泛应用铺平了道路。在此,我们全面回顾了近期有关基于 LIG 的智能医疗应用软皮肤电子器件(LIGS2E)的研究。我们首先概述了制备方法、LIG 的基本特性以及开发软皮肤电子器件所采用的标准调节策略。随后,我们概述了各种 LIGS2E 设计及其在智能医疗保健领域的各种应用。这些应用包括生物物理和生物化学传感器、生物执行器和供电系统。最后,我们探讨了在医疗保健领域实际应用 LIGS2E 所面临的潜在挑战,并对未来的研发方向提出了见解。通过阐明 LIGS2E 的能力和局限性,本综述旨在为推动智能医疗保健技术的发展做出贡献。
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引用次数: 0
Body-attachable multifunctional electronic skins for bio-signal monitoring and therapeutic applications 用于生物信号监测和治疗的可贴身多功能电子皮肤
Pub Date : 2024-06-12 DOI: 10.20517/ss.2024.09
Kang Hyeon Kim, Jeong Hyeon Kim, Yu Jin Ko, Han Eol Lee
The lack of infrastructure and accessibility in medical treatments has been considered as a global chronic issue since the concept of treatment and prevention was presented. After the COVID-19 pandemic, the medical reaction capability for epidemic outbreak/spread has been spotlighted as a critical issue to the fore worldwide. To reduce the burden on the medical system from the simultaneous disease emergence, the personalized wearable electronic systems have arisen as the next-generation biomedical monitoring/treating equipment for infectious diseases at the initial stage. In particular, electronic skin (e-skin) with its potential for multifunctional extendibility has been enabled to be applied to next-generation long-term healthcare devices with real-time biosignal sensing. Here, we introduce the recent enhancements of various e-skin systems for healthcare applications in terms of material types and device structures, including sensor components, biological signal sensing mechanisms, applicable technological advancements, and medical utilization.
自提出治疗和预防的概念以来,医疗基础设施的缺乏和可及性一直被视为一个全球性的长期问题。COVID-19 大流行之后,疫情爆发/蔓延时的医疗反应能力成为全球关注的焦点。为了减轻疾病同时出现给医疗系统带来的负担,个性化可穿戴电子系统应运而生,成为下一代传染病初期生物医学监测/治疗设备。尤其是电子皮肤(e-skin),它具有多功能扩展的潜力,可应用于下一代具有实时生物信号传感功能的长期医疗保健设备。在此,我们将从材料类型和设备结构,包括传感器组件、生物信号传感机制、适用技术进步和医疗利用等方面,介绍各种电子皮肤系统在医疗保健应用方面的最新改进。
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引用次数: 0
Liquid metal neuro-electrical interface 液态金属神经-电气接口
Pub Date : 2024-06-11 DOI: 10.20517/ss.2023.58
Xilong Zhang, Chang Liu, Rongyu Tang, Weichen Feng, Jingru Gao, Bingjie Wu, Zhongshan Deng, Jing Liu, Lei Li
Liquid metal (LM), an emerging functional material, plays increasing roles in biomedical and healthcare areas. It has particular values in neural interfaces as it combines high conductivity, flowability, and biocompatibility properties. Neuro-electrical interfaces (NEIs) are effective tools to provide a bridge between the nervous system and the outside world. The main target of developing neural interfaces is to help disabled people repair damaged nerves and enhance human capacity above normal ability. This article systematically summarizes LM-based neural interface technologies, including neural electrodes for electrical signal acquisition and administration of electrical stimulation and nerve guidance conduits for neural connectivity and functional reconstruction. The discussion begins with an overview of the fundamental properties associated with LM materials involved in the field of neural interface applications. The fabrication methods of LM-based neuro-electrodes and conduits are then introduced, and the current development status of LM-based neuro-electrodes and conduits is elaborated. Finally, the prospects and possible challenges of LM-based neural interfaces are outlined.
液态金属(LM)是一种新兴的功能材料,在生物医学和医疗保健领域发挥着越来越重要的作用。由于液态金属兼具高导电性、流动性和生物相容性,因此在神经接口方面具有特殊价值。神经电气接口(NEIs)是连接神经系统和外界的有效工具。开发神经接口的主要目标是帮助残疾人修复受损的神经,提高人体能力,使其超过正常人的能力。本文系统地总结了基于 LM 的神经接口技术,包括用于采集电信号和实施电刺激的神经电极,以及用于神经连接和功能重建的神经引导导管。讨论首先概述了神经接口应用领域所涉及的 LM 材料的基本特性。然后介绍了基于 LM 的神经电极和导管的制造方法,并阐述了基于 LM 的神经电极和导管的发展现状。最后,概述了基于 LM 的神经接口的前景和可能面临的挑战。
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引用次数: 0
3D-printed magnetic-based air pressure sensor for continuous respiration monitoring and breathing rehabilitation 用于连续呼吸监测和呼吸康复的 3D 打印磁性气压传感器
Pub Date : 2024-05-24 DOI: 10.20517/ss.2024.11
Nora Asyikin Binti Zulkifli, Wooseong Jeong, Mijin Kim, Cheolgi Kim, Young Hwii Ko, Dong Choon Hyun, Sungwon Lee
The rapid development of point-of-care testing has made prompt diagnosis, monitoring and treatment possible for many patients suffering from chronic respiratory diseases. Currently, the biggest challenge is further optimizing testing devices to facilitate more functionalities with higher efficiency and performance, along with specificity toward patient needs. By understanding that patients with chronic respiratory diseases may have difficulty breathing within a normal range, a respiration sensor is developed focusing on sensitivities in the lower air pressure range. In contrast to the simpler airflow data, the sensor can provide respiratory air pressure as an output using a magnetic-based pressure sensor. This unconventional but highly reliable approach, combined with the rest of the simple 3D-printed design of the sensor, offers a wide range of tunability and functionalities. Due to the detachable components of the respiration sensor, the device can be easily transformed into other respiratory uses such as an inspiratory muscle training device or modified to cater for higher-ranged deep breathing. Therefore, not only does it reach very low air pressure measurement (0.1 cmH2O) for normal, tidal breathing, but the sensor can also be manipulated to detect high levels of air pressure (up to 35 cmH2O for exhalation and 45 cmH2O for inhalation). With its excellent sensitivities (0.0456 mV/cmH2O for inhalation, -0.0940 mV/cmH2O for exhalation), impressive distinction between inhalation and exhalation, and fully reproducible and convenient design, we believe that this respiration sensor will pave the way for developing multimodal and multifunctional respiration sensors within the biomedical field.
护理点检测的快速发展使许多慢性呼吸系统疾病患者能够得到及时诊断、监测和治疗。目前,最大的挑战是进一步优化检测设备,使其具有更多的功能、更高的效率和性能,以及针对患者需求的特异性。由于了解到慢性呼吸系统疾病患者可能在正常范围内呼吸困难,因此开发了一种呼吸传感器,其灵敏度主要集中在较低的气压范围内。与较为简单的气流数据不同,该传感器可通过磁性压力传感器提供呼吸气压输出。这种非常规但高度可靠的方法与传感器其他简单的 3D 打印设计相结合,提供了广泛的可调性和功能。由于呼吸传感器的组件可拆卸,该设备可以很容易地转变为其他呼吸用途,如吸气肌肉训练设备或改装为更大范围的深呼吸设备。因此,它不仅能测量正常潮式呼吸的极低气压(0.1 cmH2O),还能检测高气压(呼气时高达 35 cmH2O,吸气时高达 45 cmH2O)。凭借其出色的灵敏度(吸气为 0.0456 mV/cmH2O,呼气为 -0.0940 mV/cmH2O)、令人印象深刻的吸气和呼气区分以及完全可重复和方便的设计,我们相信这种呼吸传感器将为生物医学领域开发多模态和多功能呼吸传感器铺平道路。
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引用次数: 0
Recent advances of sweat sampling, sensing, energy-harvesting and data-display toward flexible sweat electronics 汗液采样、传感、能量收集和数据显示技术在柔性汗液电子学方面的最新进展
Pub Date : 2024-05-20 DOI: 10.20517/ss.2024.04
Guangyao Zhao, Zhiyuan Li, Xingcan Huang, Qiang Zhang, Yiming Liu, Xinge Yu
Sweat contains diverse types of biomarkers that can mirror an individual’s health condition. The forefront research of sweat monitoring primarily focuses on sensing basic parameters, i.e., sweat rate and single electrolyte imbalances in controlled laboratory settings. However, recent works show the potential of sweat for the rich biomarkers in aspects of comprehensive health status display, timely safety alarming, and energy harvesting. The advances in wearable flexible electronics enable continuous, real-time, noninvasive detection of multiple sweat components, providing molecular-level insights into human physiology and psychology information; additionally, the efficient sweat extraction technologies of flexible electronics promote its application in energy harvesting, contributing to advancing a flexible sweat platform. This review comprehensively explores flexible sweat-based electronics, encompassing four key aspects: sweat sampling methods, sweat-based sensors, sweat-based energy harvesters, and sweat data display methods. Firstly, the traditional sweat-based platform is discussed in sweat sampling, sensing, and data analysis. Then, the development of wearable sweat sampling methods is discussed with a comparison of the traditional sweat collection methods. After that, the recent advances in sweat-based biosensors for monitoring diverse sweat analytes, such as the perspiration volume, glucose, lactate, and uric acid levels, are summarized. Subsequently, this review also highlights the recent progress and potential value of sweat-based energy harvesters in sweat-activated batteries and bio-fuel cells. Furthermore, multiple data display methods are proposed to achieve accurate feedback on health status, such as colorimetric techniques, light-emitting diodes, actuators, etc. Finally, this review concludes the main current challenges faced in practical applications of sweat-based bioelectronic systems and proposes a vision for the future evolution of this promising field.
汗液中含有多种生物标志物,可以反映个人的健康状况。汗液监测的前沿研究主要集中在传感基本参数,即在受控实验室环境下的出汗率和单一电解质失衡。然而,最近的研究表明,汗液在全面显示健康状况、及时发出安全警报和能量收集等方面具有丰富的生物标志物潜力。可穿戴柔性电子设备的进步实现了对多种汗液成分的连续、实时、无创检测,提供了分子层面的人体生理和心理信息;此外,柔性电子设备的高效汗液提取技术促进了其在能量收集方面的应用,有助于推动柔性汗液平台的发展。本综述从汗液采样方法、汗液传感器、汗液能量采集器和汗液数据显示方法四个方面全面探讨了基于汗液的柔性电子技术。首先,从汗液采样、传感和数据分析方面讨论了传统的汗液平台。然后,对比传统的汗液采集方法,讨论了可穿戴汗液采样方法的发展。之后,总结了用于监测各种汗液分析物(如汗液量、葡萄糖、乳酸和尿酸水平)的汗液生物传感器的最新进展。随后,本综述还重点介绍了汗液能量收集器在汗液激活电池和生物燃料电池方面的最新进展和潜在价值。此外,还提出了多种数据显示方法,如比色技术、发光二极管、致动器等,以实现对健康状况的准确反馈。最后,本综述总结了当前汗液生物电子系统在实际应用中所面临的主要挑战,并对这一前景广阔的领域的未来发展提出了展望。
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引用次数: 0
Shape-deformable Micro-LEDs for advanced displays and healthcare 用于先进显示器和医疗保健的可变形 Micro-LED
Pub Date : 2024-05-17 DOI: 10.20517/ss.2024.13
Shenghan Zou, Yuzhi Li, Zheng Gong
Recently, flexible/stretchable micro-scale light-emitting diodes (LEDs), with dimensions significantly smaller than conventional diodes used for illuminations, have emerged for promising applications in areas such as deformable displays, wearable devices for healthcare, etc . For such applications, these devices must have some unusual features that common inorganic LEDs do not intrinsically own, including conformability, biocompatibility, mechanical flexibility, etc . This Perspective focuses on summarizing the most recent progress in developing such flexible emitters based on inorganic semiconductors, followed by reviewing their potential applications. Finally, major challenges and future research directions of deformable micro-scale LEDs are presented.
最近,尺寸明显小于传统照明用二极管的柔性/可伸缩微米级发光二极管(LED)在可变形显示器、医疗保健用可穿戴设备等领域出现了广阔的应用前景。为了实现这些应用,这些设备必须具备普通无机 LED 本身不具备的一些特殊功能,包括保形性、生物相容性、机械灵活性等。本视角重点总结了在开发基于无机半导体的柔性发光体方面取得的最新进展,然后回顾了它们的潜在应用。最后,介绍了可变形微尺度发光二极管面临的主要挑战和未来的研究方向。
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引用次数: 0
Latest developments and trends in electronic skin devices 电子皮肤设备的最新发展和趋势
Pub Date : 2024-05-14 DOI: 10.20517/ss.2024.05
Pengyu Zhu, Zihan Li, Jinbo Pang, Peng He, Shuye Zhang
The skin, a vital medium for human-environment communication, stands as an indispensable and pivotal element in the realms of both production and daily life. As the landscape of science and technology undergoes gradual evolution and the demand for seamless human-machine interfaces continues to surge, an escalating need emerges for a counterpart to our biological skin - electronic skins (e-skins). Achieving high-performance sensing capabilities comparable to our skin has consistently posed a formidable challenge. In this article, we systematically outline fundamental strategies enabling e-skins with capabilities including strain sensing, pressure sensing, shear sensing, temperature sensing, humidity sensing, and self-healing. Subsequently, complex e-skin systems and current major applications were briefly introduced. We conclude by envisioning the future trajectory, anticipating continued advancements and transformative innovations shaping the dynamic landscape of e-skin technology. This article provides a profound insight into the current state of e-skins, potentially inspiring scholars to explore new possibilities.
皮肤是人类与环境交流的重要媒介,是生产和日常生活中不可或缺的关键元素。随着科学技术的逐步发展和对无缝人机界面需求的不断增长,人们对与生物皮肤相对应的电子皮肤(e-skin)的需求日益增长。实现与皮肤相媲美的高性能传感能力一直是一项艰巨的挑战。在本文中,我们系统地概述了使电子皮肤具备应变传感、压力传感、剪切传感、温度传感、湿度传感和自愈等功能的基本策略。随后,我们简要介绍了复杂的电子皮肤系统和当前的主要应用。最后,我们展望了未来的发展轨迹,预计电子皮肤技术的持续进步和变革性创新将塑造电子皮肤技术的动态景观。这篇文章深刻揭示了电子皮肤的现状,可能会激发学者们探索新的可能性。
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引用次数: 0
Controlling the lifetime of biodegradable electronics: from dissolution kinetics to trigger acceleration 控制可生物降解电子器件的使用寿命:从溶解动力学到触发加速度
Pub Date : 2024-04-23 DOI: 10.20517/ss.2024.06
You-Jung Park, Young‐In Ryu, Myung-Kyun Choi, Kyung-Sub Kim, Seung-Kyun Kang
Biodegradable electronics have revolutionized the field of medical devices by offering inherent advantages such as natural disintegration after a useful functional period, thereby eliminating the need for removal surgery. This paradigm shift addresses challenges with long-term implantation, the risks of secondary surgeries, and potential complications, offering a safer and more patient-friendly approach to temporary implantable devices. This review delves into the dissolution kinetics of materials and strategies for lifetime control providing a comprehensive overview of recent advancements in biodegradable electronics. Understanding the kinetics is crucial for meeting the required functional lifetime for implantable medical applications, which varies based on application scope and target diseases. The dissolution kinetics of silicon and biodegradable metals form the core of the discussion, focusing on recent studies aimed at controlling the dissolution rate and enhancing properties. The exploration extends to ideas for accelerating material degradation or initiating on-demand degradation in biodegradable electronics after stable function. Additionally, the compilation of encapsulation layer materials and strategies enhances understanding of how to improve the stable operation time of devices. Emphasis is placed on efforts to adjust the lifetime of biodegradable electronics, particularly in medical applications.
生物可降解电子器件通过提供固有的优势,如在有用功能期后自然分解,从而无需进行移除手术,在医疗器械领域掀起了一场革命。这种模式的转变解决了长期植入、二次手术风险和潜在并发症等难题,为临时植入式设备提供了一种更安全、更方便患者的方法。本综述深入探讨了材料的溶解动力学和寿命控制策略,全面概述了生物可降解电子器件的最新进展。要达到植入式医疗应用所需的功能寿命,了解其动力学至关重要。硅和生物可降解金属的溶解动力学是讨论的核心,重点是旨在控制溶解速率和提高性能的最新研究。探讨还延伸到加速材料降解或在生物可降解电子器件功能稳定后启动按需降解的想法。此外,通过对封装层材料和策略的汇编,加深了对如何提高器件稳定运行时间的理解。重点是努力调整可生物降解电子器件的使用寿命,特别是在医疗应用方面。
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引用次数: 0
Wearable electrochemical sensors for real-time monitoring in diabetes mellitus and associated complications 用于实时监测糖尿病及相关并发症的可穿戴电化学传感器
Pub Date : 2024-04-23 DOI: 10.20517/ss.2024.02
Han Hee Jung, Hyeokjun Lee, Junwoo Yea, Kyung-In Jang
This comprehensive review underscores the pivotal role wearable electrochemical sensors play in the proactive management and prevention of diabetes mellitus (DM) and its associated complications. Acknowledging the substantial impact of DM on individuals and the urgency for effective monitoring strategies, wearable sensors have emerged as a pragmatic solution. These sensors can detect analytical signals from biofluids, including sweat, tears, saliva, and interstitial fluid (ISF), employing minimally invasive techniques facilitated by technological advancements. The seamless integration of these sensors with computational platforms such as smartphones enhances their practicality for routine use. The review systematically explores diverse methodologies, encompassing both enzymatic and non-enzymatic principles, employed for the surveillance of analytes within biofluids. These foundational principles are meticulously applied to wearable devices, affording point-of-care solutions catering to the detection of individual analytes or simultaneous multiplexed analyte detection. The integration of wireless systems and the incorporation of machine learning algorithms introduce a layer of sophistication, elevating the capability of these sensors for the nuanced monitoring of DM and its complications. Through an in-depth analysis of these advancements, this review describes the significant potential of wearable electrochemical sensors as an essential tool for real-time monitoring and managing DM. The diverse approaches presented underscore the adaptability, versatility, and inherent efficacy of these sensors in addressing the multifaceted challenges intrinsic to DM and its associated complications within academic discourse.
这篇综述强调了可穿戴电化学传感器在主动管理和预防糖尿病(DM)及其相关并发症方面发挥的关键作用。认识到糖尿病对个人的重大影响以及制定有效监测策略的紧迫性,可穿戴传感器已成为一种实用的解决方案。这些传感器可以利用技术进步带来的微创技术,从汗液、泪液、唾液和组织间液(ISF)等生物流体中检测分析信号。这些传感器与智能手机等计算平台的无缝集成提高了其日常使用的实用性。本综述系统地探讨了用于监测生物流体中分析物的各种方法,包括酶和非酶原理。这些基本原理被细致地应用到可穿戴设备中,提供了满足单个分析物检测或同步多重分析物检测的护理点解决方案。无线系统的集成和机器学习算法的加入使这些传感器的功能更加复杂,从而提高了对糖尿病及其并发症进行细致监测的能力。通过对这些进展的深入分析,本综述介绍了可穿戴电化学传感器作为实时监测和管理 DM 的重要工具所具有的巨大潜力。所介绍的各种方法强调了这些传感器在应对 DM 及其相关并发症所固有的多方面挑战方面的适应性、多功能性和固有功效。
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引用次数: 0
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Soft science
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