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A chance to cut is a chance to cure. 切割的机会就是治疗的机会。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-10-04 DOI: 10.1016/j.amjsurg.2024.115995
Eleanor A Fallon, Sarah B Fisher
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引用次数: 0
Practice variations, trends, and outcomes of drain use in thyroidectomy: A NSQIP study. 甲状腺切除术中引流管使用的实践差异、趋势和结果:一项 NSQIP 研究。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-10-04 DOI: 10.1016/j.amjsurg.2024.115998
Kelvin Memeh, Sara Abou Azar, Oluwasegun Afolaranmi, Tanaz M Vaghaiwalla

Background: The benefit of drains remains unclear and variable among thyroid surgeons. This study examines the utility and trend in drain use after thyroidectomy.

Method: This is a retrospective cross-sectional study utilizing a pooled sample of thyroidectomy patients from the 2016-2019 NSQIP. The impact of drain use on outcomes of interest (rate of postoperative neck hematoma (PNH)-primary outcome, and length-of-stay (LOS)-secondary outcome), as well as year-over-year and practice variations were evaluated using inverse-probability-weighted-regression adjustment and multivariable logistic regression analyses.

Results: Of 24,370 patients, 6673(27.4 ​%) received drains. The average LOS and PNH rates were 27.3 ​h and 1.87 %, respectively. Drain use increased year-over-year for concomitant neck dissections (OR ​= ​1.08,p ​= ​0.002). Year-over-year odds of drain use trended down across specialties (OR ​= ​0.96,p ​= ​0.005); however, ENT used drains more frequently than General Surgeons (RR ​= ​3.06, 95%CI ​= ​2.91-3.22). Drains were associated with longer LOS (mean-difference ​= ​9.6hrs, 95%CI 8.51-10.62) with no effect on PNH rates (RR ​= ​0.96,p ​< ​0.05).

Conclusion: Drain use is decreasing, but practice variations across specialties persist. Post-thyroidectomy drain use was associated with longer LOS with no effect on PNHR.

背景:甲状腺外科医生对引流管的益处仍不清楚,且存在差异。本研究探讨了甲状腺切除术后使用引流管的效用和趋势:这是一项回顾性横断面研究,采用的是 2016-2019 NSQIP 中甲状腺切除术患者的汇总样本。使用反概率加权回归调整和多变量逻辑回归分析评估了引流管的使用对相关结果(术后颈部血肿率(PNH)--主要结果和住院时间(LOS)--次要结果)的影响,以及同比和实践的变化:在 24,370 名患者中,有 6673 人(27.4%)接受了引流术。平均住院时间和 PNH 发生率分别为 27.3 小时和 1.87%。同时发生颈部解剖的患者使用引流管的比例逐年增加(OR = 1.08,P = 0.002)。各专科使用引流管的同比几率呈下降趋势(OR = 0.96,p = 0.005);然而,耳鼻喉科比普外科更常使用引流管(RR = 3.06, 95%CI = 2.91-3.22)。引流管与较长的 LOS 相关(平均差异 = 9.6 小时,95%CI = 8.51-10.62),但对 PNH 的发生率没有影响(RR = 0.96,P 结论:引流管的使用正在减少,但对 PNH 的发生率没有影响(RR = 0.96,P = 0.005):引流管的使用正在减少,但各专科之间的实践差异依然存在。甲状腺切除术后引流管的使用与较长的LOS有关,但对PNHR没有影响。
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引用次数: 0
Caudate lobe and posterosuperior segment hepatectomy using the robotic approach. Outcome analysis of liver resection in difficult locations 使用机器人方法进行尾状叶和后上段肝切除术。疑难部位肝切除术的结果分析。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-10-04 DOI: 10.1016/j.amjsurg.2024.115996
Trevor Jones, Maria Christodoulou, Sharona Ross, Tara M. Pattilachan, Alexander Rosemurgy, Iswanto Sucandy

Background

Caudate and posterosuperior hepatectomy are technically challenging resections, especially in a minimally invasive approach. We aimed to analyze the outcomes of isolated caudate resection (ICR), en-bloc caudate resection with right/left hepatic lobectomy (ECR), and posterosuperior segment resection (PSR) using our institutional database.

Methods

Following IRB approval, we prospectively followed 500 consecutive patients between 2013 and 2023 who underwent robotic hepatectomy. Posterosuperior segments include segment 4 ​A, 7, and 8. The data are presented as median (mean ​± ​standard deviation).

Results

Of the 500 patients included in this study, 19 (4 ​%) underwent ICR, 65 (13 ​%) underwent ECR, and 131 (26 ​%) patients underwent PSR. ECR was associated with significantly longer operative time, increased EBL, and longer LOS when compared with those of ICR and PSR. The patients who underwent ICR had the shortest operation duration, lowest EBL, and shortest LOS compared to ECR and PSR.

Conclusions

Robotic resection of liver tumors located in difficult segments is safe and feasible with excellent clinical and oncological outcomes. With appropriate expertise, a minimally invasive approach to those operations should not be avoided.
背景:尾段和后上段肝切除术是技术上具有挑战性的切除术,尤其是在微创方法中。我们旨在利用本机构的数据库分析孤立尾状切除术(ICR)、右/左肝叶切除术(ECR)和后上段切除术(PSR)的疗效:在获得 IRB 批准后,我们对 2013 年至 2023 年间接受机器人肝切除术的 500 例连续患者进行了前瞻性随访。后上段包括 4 A、7 和 8 段。数据以中位数(平均值±标准差)表示:结果:在纳入本研究的 500 例患者中,19 例(4%)接受了 ICR,65 例(13%)接受了 ECR,131 例(26%)接受了 PSR。与 ICR 和 PSR 相比,ECR 的手术时间明显更长、EBL 增加、LOS 延长。与ECR和PSR相比,接受ICR的患者手术时间最短、EBL最低、LOS最短:结论:机器人切除位于难切区段的肝脏肿瘤安全可行,临床和肿瘤学效果极佳。只要具备适当的专业知识,就不应避免采用微创方法进行这些手术。
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引用次数: 0
The impact of routine cholangiography for asymptomatic patients after cholecystostomy insertion for acute cholecystitis 对急性胆囊炎胆囊造口术后无症状患者进行常规胆管造影的影响。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-10-04 DOI: 10.1016/j.amjsurg.2024.116000
Tal Weiss , Rotem Franko , Lauren Lahav , Guy Lifshitz , Shmuel Avital , Yaron Rudnicki

Background

We aim to investigate the impact of routine cholangiography on asymptomatic patients with percutaneous cholecystostomy (PCC) for acute cholecystitis (AC).

Methods

The study included all patients treated with PCC for AC from 2017 to 2020 ​at a single academic center. Patients who underwent routine cholangiography within 30 days post-discharge while asymptomatic were compared to patients who were only followed clinically.

Results

The groups (cholangiography group, n ​= ​44, and control group, n ​= ​145) were similar in terms of age, comorbidities, and clinical presentation. The readmission rate for biliary disease in the cholangiography group was nearly half that of the control group (22.7 ​% vs. 40.7 ​%, p ​= ​0.05) over an average follow-up of 10.4 months. The time to drain removal, cholecystectomy rate, and time to operation were comparable between the groups (42 vs. 40 days, p ​= ​0.47, 52.3 ​% vs 53.1 ​%, p ​= ​NS and 69 vs. 82 days, p ​= ​0.17, respectively).

Conclusions

Routine cholangiography can help reduce biliary disease readmissions among asymptomatic patients with PCC for AC without delaying further treatment.
背景:我们旨在研究常规胆管造影对急性胆囊炎(AC)经皮胆囊造口术(PCC)无症状患者的影响:我们旨在研究常规胆管造影对急性胆囊炎(AC)经皮胆囊造口术(PCC)无症状患者的影响:研究纳入了2017年至2020年在一家学术中心接受经皮胆囊造口术治疗的所有急性胆囊炎患者。将出院后30天内接受常规胆管造影术且无症状的患者与仅接受临床随访的患者进行比较:两组患者(胆管造影组,n = 44;对照组,n = 145)的年龄、合并症和临床表现相似。在平均 10.4 个月的随访期间,胆管造影组的胆道疾病再入院率几乎是对照组的一半(22.7% 对 40.7%,P = 0.05)。两组患者移除引流管的时间、胆囊切除率和手术时间相当(分别为42天 vs. 40天,p = 0.47;52.3% vs. 53.1%,p = NS;69天 vs. 82天,p = 0.17):常规胆管造影有助于减少无症状的 AC PCC 患者的胆道疾病再入院率,同时不会延误进一步治疗。
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引用次数: 0
Implementing a global mentoring program: A call to action for mentorship in surgery. 实施全球指导计划:外科导师制的行动号召。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-10-04 DOI: 10.1016/j.amjsurg.2024.115997
Joanna Chen, Anisa Nazir, Ayla Gerk, Pedra Rabiee, Isabella Faria, Kaela Blake, Tanaz Vaghaiwalla

Background: The Gender Equity Initiative in Global Surgery organization launched a mentorship program to address the limited opportunities available in low-and-middle-income countries (LMICs). We aimed to evaluate the utility of the virtual program in bridging this critical gap.

Methods: A retrospective review of program surveys containing quantitative and qualitative questions from 2022 to 2023 was performed.

Results: Of n ​= ​193 applicants, 81.3 ​% (157/193) identified as women, and 69.4 ​% (134/193) reported no prior mentorship. Applicants were from 41 countries (35 LMICs). The most requested specialties were general surgery (27.9 ​%, 54/193), neurosurgery (18.1 ​%, 35/193), and cardiothoracic surgery (11.4 ​%, 22/193). 55.9 ​% (108/193) preferred mentors from other countries (United States, United Kingdom, Canada), while 13.9 ​% (27/193) preferred mentors from their country. Ultimately, 48 applicants were matched with 13 mentors.

Conclusions: Demand for the program surpassed capacity, highlighting a need for mentorship opportunities for women overall, particularly in LMICs.

背景:全球外科性别平等倡议组织发起了一项导师计划,以解决中低收入国家(LMIC)机会有限的问题。我们旨在评估该虚拟项目在缩小这一关键差距方面的效用:我们对 2022 年至 2023 年期间包含定量和定性问题的项目调查进行了回顾性审查:在 n = 193 名申请人中,81.3%(157/193)自称女性,69.4%(134/193)称之前没有接受过指导。申请人来自 41 个国家(35 个低收入和中等收入国家)。申请最多的专业是普通外科(27.9%,54/193)、神经外科(18.1%,35/193)和心胸外科(11.4%,22/193)。55.9%的申请人(108/193)希望导师来自其他国家(美国、英国、加拿大),13.9%的申请人(27/193)希望导师来自本国。最终,48 名申请人与 13 名导师配对成功:结论:对该计划的需求超过了计划的能力,这凸显了妇女对导师机会的整体需求,尤其是在低收入、中等收入国家。
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引用次数: 0
Thyroidectomy outcomes in admitted patients are indeed worse than for outpatents: Providers must now acknowledge and respond. 入院患者的甲状腺切除术效果确实比门诊患者差:医疗服务提供者现在必须认识到这一点并做出回应。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-10-03 DOI: 10.1016/j.amjsurg.2024.115992
Aimee N Di Marco
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引用次数: 0
Racial disparities in thyroid cancer outcomes: A systematic review. 甲状腺癌结果中的种族差异:系统综述。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-09-28 DOI: 10.1016/j.amjsurg.2024.115991
Polina Zmijewski, Chibueze Nwaiwu, Hayato Nakanishi, Soroush Farsi, Jessica Fazendin, Brenessa Lindeman, Herbert Chen, Andrea Gillis

Introduction: Racial disparities in surgical outcomes are well described, but a paucity of literature exists examining trends in outcomes of thyroid cancer. We performed a systematic review of studies on thyroid cancer outcomes to better delineate the impact of race.

Methods: A comprehensive search strategy was performed in several academic databases for articles on thyroid cancer and surgical outcomes in accordance with PRISMA guidelines. A total of 1771 abstracts were reviewed. Abstracts were screened by two independent reviewers with disagreements resolved by a third. Studies that were based in the United States, included single center, unique data, focused on outcomes of differentiated thyroid cancer, were performed on adults >18 years old, and reported race in their results were included. Chi square statistics with Yates correction were calculated on the compiled data. The protocol was registered on PROSPERO (CRD42022300021).

Results: Twelve studies met inclusion criteria with data on 7,221patients. Among the included studies, our study consists of 67 ​% White patients, 22 ​% Black patients, 7 ​% Hispanic patients, and 3 ​% Asian patients. Extrathyroidal extension was observed in 8.4 ​% (n ​= ​13) of White patients. In comparison to White patients, Black (18.4 ​%, n ​= ​21, p ​= ​0.024) and Hispanic patients (28.3 ​%, n ​= ​30, p ​< ​0.001) had a higher incidence of extrathyroidal extension, while a similar incidence was observed in Asian patients (14.0 ​%, n ​= ​8, p ​= ​0.336). Compared to White patients (22.2 ​%, n ​= ​34), Black (12.4 ​%, n ​= ​13, p ​= ​0.065), Hispanic (16.0 ​%, n ​= ​15, p ​= ​0.301), and Asian (18.4 ​%, n ​= ​9, p ​= ​0.709) patients had a similar incidence of T1a stage. White patients had 10.1 ​% (n ​= ​54) recurrence rates, and Black (13.5 ​%, n ​= ​7, p ​= ​0.595), Hispanic (10.5 ​%, n ​= ​2, p ​= ​1.000), and Asian (11.1 ​%, n ​= ​3, p ​= ​1.000) patients had similar recurrence rates.

Conclusions: Race is seldom reported in outcomes on studies of thyroid cancer. From our analysis we conclude that non-White patients may have a higher risk of more advanced local disease at presentation. More data with granular detail on race is necessary to better understand racial disparities in thyroid cancer outcomes and how to alleviate them.

导言:手术治疗结果中的种族差异已被充分描述,但研究甲状腺癌治疗结果趋势的文献却很少。我们对甲状腺癌治疗效果的研究进行了系统回顾,以更好地界定种族的影响:根据 PRISMA 指南,我们在多个学术数据库中对有关甲状腺癌和手术结果的文章进行了全面检索。共审阅了 1771 篇摘要。摘要由两名独立审稿人筛选,有异议的由第三名审稿人解决。纳入的研究均以美国为基地,包含单个中心的独特数据,重点关注分化型甲状腺癌的治疗效果,研究对象为年龄大于 18 岁的成年人,并在研究结果中报告了种族情况。对汇总的数据进行了带耶茨校正的卡方统计。研究方案已在 PROSPERO(CRD42022300021)上注册:结果:12 项研究符合纳入标准,涉及 7221 名患者的数据。在纳入的研究中,我们的研究包括67%的白人患者、22%的黑人患者、7%的西班牙裔患者和3%的亚洲患者。在白人患者中,8.4%(n = 13)观察到甲状腺外扩展。与白人患者相比,黑人患者(18.4%,n = 21,p = 0.024)和西班牙裔患者(28.3%,n = 30,p 结论:甲状旁腺外扩是一种常见的甲状腺疾病:在甲状腺癌的研究结果中,很少有关于种族的报告。根据我们的分析,我们得出结论:非白人患者在发病时罹患晚期局部疾病的风险可能更高。要想更好地了解甲状腺癌结果中的种族差异以及如何缓解这些差异,就需要更多有关种族的详细数据。
{"title":"Racial disparities in thyroid cancer outcomes: A systematic review.","authors":"Polina Zmijewski, Chibueze Nwaiwu, Hayato Nakanishi, Soroush Farsi, Jessica Fazendin, Brenessa Lindeman, Herbert Chen, Andrea Gillis","doi":"10.1016/j.amjsurg.2024.115991","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2024.115991","url":null,"abstract":"<p><strong>Introduction: </strong>Racial disparities in surgical outcomes are well described, but a paucity of literature exists examining trends in outcomes of thyroid cancer. We performed a systematic review of studies on thyroid cancer outcomes to better delineate the impact of race.</p><p><strong>Methods: </strong>A comprehensive search strategy was performed in several academic databases for articles on thyroid cancer and surgical outcomes in accordance with PRISMA guidelines. A total of 1771 abstracts were reviewed. Abstracts were screened by two independent reviewers with disagreements resolved by a third. Studies that were based in the United States, included single center, unique data, focused on outcomes of differentiated thyroid cancer, were performed on adults >18 years old, and reported race in their results were included. Chi square statistics with Yates correction were calculated on the compiled data. The protocol was registered on PROSPERO (CRD42022300021).</p><p><strong>Results: </strong>Twelve studies met inclusion criteria with data on 7,221patients. Among the included studies, our study consists of 67 ​% White patients, 22 ​% Black patients, 7 ​% Hispanic patients, and 3 ​% Asian patients. Extrathyroidal extension was observed in 8.4 ​% (n ​= ​13) of White patients. In comparison to White patients, Black (18.4 ​%, n ​= ​21, p ​= ​0.024) and Hispanic patients (28.3 ​%, n ​= ​30, p ​< ​0.001) had a higher incidence of extrathyroidal extension, while a similar incidence was observed in Asian patients (14.0 ​%, n ​= ​8, p ​= ​0.336). Compared to White patients (22.2 ​%, n ​= ​34), Black (12.4 ​%, n ​= ​13, p ​= ​0.065), Hispanic (16.0 ​%, n ​= ​15, p ​= ​0.301), and Asian (18.4 ​%, n ​= ​9, p ​= ​0.709) patients had a similar incidence of T1a stage. White patients had 10.1 ​% (n ​= ​54) recurrence rates, and Black (13.5 ​%, n ​= ​7, p ​= ​0.595), Hispanic (10.5 ​%, n ​= ​2, p ​= ​1.000), and Asian (11.1 ​%, n ​= ​3, p ​= ​1.000) patients had similar recurrence rates.</p><p><strong>Conclusions: </strong>Race is seldom reported in outcomes on studies of thyroid cancer. From our analysis we conclude that non-White patients may have a higher risk of more advanced local disease at presentation. More data with granular detail on race is necessary to better understand racial disparities in thyroid cancer outcomes and how to alleviate them.</p>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"115991"},"PeriodicalIF":2.7,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practice variation in venous thromboembolism prophylaxis in adolescent trauma patients: A comparative analysis of pediatric, adult, and mixed trauma centers 青少年创伤患者静脉血栓栓塞预防措施的实践差异:儿科、成人和混合创伤中心的比较分析。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-09-27 DOI: 10.1016/j.amjsurg.2024.115994
Janelle Cyprich , Amy H. Kaji , George A. Singer , Alexander C. Schwed , Jessica A. Keeley

Introduction

Adolescent trauma patients are at increased risk of venous thromboembolism (VTE). It is unclear whether VTE prophylaxis practice patterns differ across trauma center types.

Methods

The ACS-TQP database was queried for patients aged 12-17 admitted to a pediatric, adult, or mixed level I/II trauma center. VTE prophylaxis was compared between center types. Preplanned subgroup analyses were performed to evaluate guideline adherence.

Results

Of 101,010 patients included, 35 ​% were treated at a pediatric trauma center (PTC), 43 ​% at a mixed trauma center (MTC), and 22 ​% at an adult trauma center (ATC). VTE prophylaxis was more common at ATCs and MTCs compared to PTCs (51.0 ​% vs 24.9 ​% vs 5.0 ​%,p ​< ​0.001). This trend persisted in subgroup analyses of patients aged 16–17 (63.8 ​% vs 40.5 ​% vs 6.4 ​%,p ​< ​0.001) and with injury severity score greater than 25 (83.8 ​% vs 74.0 ​% vs 35.1 ​%,p ​< ​0.001).

Conclusion

VTE prophylaxis is administered more frequently to adolescent trauma patients treated at ATCs and MTCs compared to PTCs despite published guidelines. Prospective studies are needed to assess the clinical utility of VTE prophylaxis in the adolescent trauma population.
导言:青少年创伤患者罹患静脉血栓栓塞症(VTE)的风险较高。目前还不清楚不同类型的创伤中心在预防 VTE 方面的做法是否有所不同:方法:在 ACS-TQP 数据库中查询了儿科、成人或 I/II 级混合创伤中心收治的 12-17 岁患者。对不同类型中心的 VTE 预防措施进行了比较。为评估指南遵守情况,进行了预先计划的亚组分析:在纳入的 101010 名患者中,35% 在儿科创伤中心 (PTC) 接受治疗,43% 在混合创伤中心 (MTC) 接受治疗,22% 在成人创伤中心 (ATC) 接受治疗。与儿科创伤中心(PTC)相比,成人创伤中心(ATC)和混合创伤中心(MTC)采用 VTE 预防措施的比例更高(51.0% vs 24.9% vs 5.0%,p):尽管有已发布的指南,但与 PTC 相比,在 ATC 和 MTC 接受治疗的青少年创伤患者更常接受 VTE 预防。需要进行前瞻性研究,以评估 VTE 预防在青少年创伤人群中的临床实用性。
{"title":"Practice variation in venous thromboembolism prophylaxis in adolescent trauma patients: A comparative analysis of pediatric, adult, and mixed trauma centers","authors":"Janelle Cyprich ,&nbsp;Amy H. Kaji ,&nbsp;George A. Singer ,&nbsp;Alexander C. Schwed ,&nbsp;Jessica A. Keeley","doi":"10.1016/j.amjsurg.2024.115994","DOIUrl":"10.1016/j.amjsurg.2024.115994","url":null,"abstract":"<div><h3>Introduction</h3><div>Adolescent trauma patients are at increased risk of venous thromboembolism (VTE). It is unclear whether VTE prophylaxis practice patterns differ across trauma center types.</div></div><div><h3>Methods</h3><div>The ACS-TQP database was queried for patients aged 12-17 admitted to a pediatric, adult, or mixed level I/II trauma center. VTE prophylaxis was compared between center types. Preplanned subgroup analyses were performed to evaluate guideline adherence.</div></div><div><h3>Results</h3><div>Of 101,010 patients included, 35 ​% were treated at a pediatric trauma center (PTC), 43 ​% at a mixed trauma center (MTC), and 22 ​% at an adult trauma center (ATC). VTE prophylaxis was more common at ATCs and MTCs compared to PTCs (51.0 ​% vs 24.9 ​% vs 5.0 ​%,p ​&lt; ​0.001). This trend persisted in subgroup analyses of patients aged 16–17 (63.8 ​% vs 40.5 ​% vs 6.4 ​%,p ​&lt; ​0.001) and with injury severity score greater than 25 (83.8 ​% vs 74.0 ​% vs 35.1 ​%,p ​&lt; ​0.001).</div></div><div><h3>Conclusion</h3><div>VTE prophylaxis is administered more frequently to adolescent trauma patients treated at ATCs and MTCs compared to PTCs despite published guidelines. Prospective studies are needed to assess the clinical utility of VTE prophylaxis in the adolescent trauma population.</div></div>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"238 ","pages":"Article 115994"},"PeriodicalIF":2.7,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142374891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subsequent percutaneous breast biopsies after initial atypia diagnosis: The patient burden of long-term follow up. 初次非典型诊断后的后续经皮乳腺活检:长期随访给患者带来的负担。
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-09-27 DOI: 10.1016/j.amjsurg.2024.115993
Juliet C Dalton, Samantha M Thomas, Akiko Chiba, Ton Wang, E Shelley Hwang, Jennifer K Plichta

Background: Breast atypia increases overall breast cancer risk, potentially necessitating future interventions. This study examines the frequency and outcomes of additional percutaneous biopsies after an atypia diagnosis.

Methods: Adult patients with breast atypia (atypical ductal hyperplasia, atypical lobular hyperplasia, lobular carcinoma in situ) at a single institution were reviewed for subsequent core needle biopsies (CNBs) and corresponding malignant outcomes.

Results: Among 432 patients, median age at diagnosis was 54.8 ​y. Seventy-one (71/432, 16.4 ​%) patients developed a breast malignancy. During a median follow-up of 7.4 ​y, 113 patients underwent 149 additional CNBs. Twenty-six patients (26/113, 23.0 ​%) had >2 additional CNBs. Approximately half (79/149, 53.0 ​%) of all additional CNBs occurred within 5 years after breast atypia diagnosis.

Conclusion: A considerable number of patients with breast atypia undergo additional percutaneous biopsies, especially within 5 years post-atypia diagnosis. Our study highlights the significant burden of surveillance and the need for tailored follow-up strategies.

背景:乳腺不典型性会增加患乳腺癌的总体风险,因此今后可能有必要采取干预措施。本研究探讨了乳腺不典型增生确诊后进行额外经皮活检的频率和结果:方法:研究人员对一家医疗机构的成年乳腺非典型增生(非典型导管增生、非典型小叶增生、小叶原位癌)患者的后续核心针活检(CNB)和相应的恶性结果进行了回顾性分析:在432名患者中,确诊时的中位年龄为54.8岁。71名患者(71/432,16.4%)罹患乳腺恶性肿瘤。在中位 7.4 年的随访期间,113 名患者又接受了 149 次 CNB。26名患者(26/113,23.0%)接受了2次以上的CNB。大约一半(79/149,53.0%)的额外 CNB 发生在乳腺不典型诊断后的 5 年内:结论:相当多的乳腺不典型增生患者接受了额外的经皮活检,尤其是在确诊乳腺不典型增生后的 5 年内。我们的研究凸显了监测的巨大负担以及制定有针对性的随访策略的必要性。
{"title":"Subsequent percutaneous breast biopsies after initial atypia diagnosis: The patient burden of long-term follow up.","authors":"Juliet C Dalton, Samantha M Thomas, Akiko Chiba, Ton Wang, E Shelley Hwang, Jennifer K Plichta","doi":"10.1016/j.amjsurg.2024.115993","DOIUrl":"https://doi.org/10.1016/j.amjsurg.2024.115993","url":null,"abstract":"<p><strong>Background: </strong>Breast atypia increases overall breast cancer risk, potentially necessitating future interventions. This study examines the frequency and outcomes of additional percutaneous biopsies after an atypia diagnosis.</p><p><strong>Methods: </strong>Adult patients with breast atypia (atypical ductal hyperplasia, atypical lobular hyperplasia, lobular carcinoma in situ) at a single institution were reviewed for subsequent core needle biopsies (CNBs) and corresponding malignant outcomes.</p><p><strong>Results: </strong>Among 432 patients, median age at diagnosis was 54.8 ​y. Seventy-one (71/432, 16.4 ​%) patients developed a breast malignancy. During a median follow-up of 7.4 ​y, 113 patients underwent 149 additional CNBs. Twenty-six patients (26/113, 23.0 ​%) had >2 additional CNBs. Approximately half (79/149, 53.0 ​%) of all additional CNBs occurred within 5 years after breast atypia diagnosis.</p><p><strong>Conclusion: </strong>A considerable number of patients with breast atypia undergo additional percutaneous biopsies, especially within 5 years post-atypia diagnosis. Our study highlights the significant burden of surveillance and the need for tailored follow-up strategies.</p>","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":" ","pages":"115993"},"PeriodicalIF":2.7,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142379023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emeritus Editorial Board 荣誉编辑委员会
IF 2.7 3区 医学 Q1 SURGERY Pub Date : 2024-09-26 DOI: 10.1016/j.amjsurg.2024.115965
{"title":"Emeritus Editorial Board","authors":"","doi":"10.1016/j.amjsurg.2024.115965","DOIUrl":"10.1016/j.amjsurg.2024.115965","url":null,"abstract":"","PeriodicalId":7771,"journal":{"name":"American journal of surgery","volume":"237 ","pages":"Article 115965"},"PeriodicalIF":2.7,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142322975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
American journal of surgery
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