Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.06.148
Dilek Beser, Izzet Ozgurluk, Deniz Oluklu, Esra z, Ozgur Kara, Atakan Tanacan, Dilek Sahin
Objective: We aimed to investigate the effect of systemic inflammation indices in predicting pregnancy outcomes of inflammatory bowel disease (IBD). Materials and Methods: Pregnant women with Crohn’s disease (CD) and Ulcerative colitis (UC) were identified from hospital medical records. Demographic features, disease type, duration and activity, and obstetric outcomes such as gestational age, mode of delivery, birth weight, Apgar scores at the first and fifth minutes after birth, and neonatal intensive care unit admission were assessed. Laboratory tests were conducted in the first trimester, including complete blood count and liver function. Neutrophil/lymphocyte ratio (NLR), derived neutrophil/lymphocyte ratio (dNLR), systemic inflammation index (SII), systemic inflammation response index (SIR-I), and aspartate transaminase/platelet ratio (APRI) were measured. Results: The study involved 48 pregnant women, 26 diagnosed with UC and 22 with CD. At least one attack occurred in 31.3% of all patients during pregnancy. For predicting attacks during pregnancy, the optimal cutoff values of dNLR, NLR, SII, SIR-I, and APRI were 2.12 (86.7% sensitivity, 82.8% specificity), 2.89 (86.7% sensitivity, 81.8% specificity), 850.7 109/L (66.7% sensitivity, 63.6% specificity), 1.06 109/L (66.7% sensitivity, 72.7% specificity), 0.051 (80% sensitivity, 75.8% specificity), respectively. A cut-off value of 0.07 for APRI ( 71.4% sensitivity and 73.2% specificity) was calculated to predict low birth weight. Conclusion: NLR, dNLR, SII, SIR-I, and APRI might help predict attacks in pregnant women with IBD. In addition, APRI may be utilized to predict low birth weight in pregnant women with IBD.
{"title":"Impact Of Neutrophil-to-lymphocyte ratio (NLR), Derived neutrophil-to-lymphocyte ratio (dNLR), Systemic inflammation index (SII), Systemic inflammation response index (SIR-I), and Aspartate transaminase/platelet ratio (APRI) In Predicting Pregnancy Outcomes Of Inflammatory Bowel Disease","authors":"Dilek Beser, Izzet Ozgurluk, Deniz Oluklu, Esra z, Ozgur Kara, Atakan Tanacan, Dilek Sahin","doi":"10.5455/annalsmedres.2023.06.148","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.06.148","url":null,"abstract":"Objective: We aimed to investigate the effect of systemic inflammation indices in predicting pregnancy outcomes of inflammatory bowel disease (IBD). Materials and Methods: Pregnant women with Crohn’s disease (CD) and Ulcerative colitis (UC) were identified from hospital medical records. Demographic features, disease type, duration and activity, and obstetric outcomes such as gestational age, mode of delivery, birth weight, Apgar scores at the first and fifth minutes after birth, and neonatal intensive care unit admission were assessed. Laboratory tests were conducted in the first trimester, including complete blood count and liver function. Neutrophil/lymphocyte ratio (NLR), derived neutrophil/lymphocyte ratio (dNLR), systemic inflammation index (SII), systemic inflammation response index (SIR-I), and aspartate transaminase/platelet ratio (APRI) were measured. Results: The study involved 48 pregnant women, 26 diagnosed with UC and 22 with CD. At least one attack occurred in 31.3% of all patients during pregnancy. For predicting attacks during pregnancy, the optimal cutoff values of dNLR, NLR, SII, SIR-I, and APRI were 2.12 (86.7% sensitivity, 82.8% specificity), 2.89 (86.7% sensitivity, 81.8% specificity), 850.7 109/L (66.7% sensitivity, 63.6% specificity), 1.06 109/L (66.7% sensitivity, 72.7% specificity), 0.051 (80% sensitivity, 75.8% specificity), respectively. A cut-off value of 0.07 for APRI ( 71.4% sensitivity and 73.2% specificity) was calculated to predict low birth weight. Conclusion: NLR, dNLR, SII, SIR-I, and APRI might help predict attacks in pregnant women with IBD. In addition, APRI may be utilized to predict low birth weight in pregnant women with IBD.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.09.242
Murat lu
Introduction: Acute kidney injury is one of the most widespread problems in critical patients in intensive care. It leads to severe morbidity and mortality. Although the indications for emergency dialysis are well known, the timing for initiating CRRT in the critical patient is still unclear. This study examines the effect on mortality of early CRRT by retrospectively scanning critical patients who received CRRT in intensive care. Material and Method: Demographic, clinical, and laboratory data were recorded by retrospectively scanning patients aged over 18, with no previously known chronic kidney disease, and receiving only CRRT, who were treated in intensive care over a one-year period. The patients were divided into two groups, an early group consisting of KDIGO stages 1 and 2, and a late group consisting of KDIGO stage 3. These were than examined in terms of 28-day mortality. Results: Forty-eight patients with a mean age of 65.94±19.61 years were included in the study. Twenty-eight (58.3%) patients were men. Cardiovascular diseases were the most frequent diagnoses, in 16 (33.3%) patients, and comorbidity was detected in 32 (66.7%). SOFA, blood urea nitrogen, creatinine, and procalcitonin values differed between the groups, but no difference was observed in 28-day mortality. Conclusion: The study results showed that early or late application of CRRT has no positive effect on survival, but further randomized studies on the subject are now needed.
{"title":"Continuous renal replacement therapy in intensive care: When is the optimal timing?","authors":"Murat lu","doi":"10.5455/annalsmedres.2023.09.242","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.09.242","url":null,"abstract":"Introduction: Acute kidney injury is one of the most widespread problems in critical patients in intensive care. It leads to severe morbidity and mortality. Although the indications for emergency dialysis are well known, the timing for initiating CRRT in the critical patient is still unclear. This study examines the effect on mortality of early CRRT by retrospectively scanning critical patients who received CRRT in intensive care. Material and Method: Demographic, clinical, and laboratory data were recorded by retrospectively scanning patients aged over 18, with no previously known chronic kidney disease, and receiving only CRRT, who were treated in intensive care over a one-year period. The patients were divided into two groups, an early group consisting of KDIGO stages 1 and 2, and a late group consisting of KDIGO stage 3. These were than examined in terms of 28-day mortality. Results: Forty-eight patients with a mean age of 65.94±19.61 years were included in the study. Twenty-eight (58.3%) patients were men. Cardiovascular diseases were the most frequent diagnoses, in 16 (33.3%) patients, and comorbidity was detected in 32 (66.7%). SOFA, blood urea nitrogen, creatinine, and procalcitonin values differed between the groups, but no difference was observed in 28-day mortality. Conclusion: The study results showed that early or late application of CRRT has no positive effect on survival, but further randomized studies on the subject are now needed.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.08.200
Ebru Canakci, Ilker Coskun
Aim: Postspinal puncture headache (PDPH) affects postoperative recovery and patients' quality of life after surgery. PDPH is the most common complication of spinal anaesthesia that affects patients' well-being the most. The epidural blood patch (EBP) is the gold standard for interventional treatment of PDPH. Sphenopalatine ganglion block (SPGB), a new noninvasive method for treating PDPH, has come to the forefront. SPGB is noninvasive and very easy to perform compared with EBP. This study aims to compare the efficacy of the two interventional methods in treating PDPH. Material and Method: Between January 1, 2018, and February 1, 2023, 30 cases diagnosed with PDPH underwent EBP and 28 SPGB. Case demographics, type of surgery performed, whether complications occurred after the procedure, and the amount of acetaminophen taken within 24 hours were recorded in mg. The VAS scores were recorded 8 times, in the first half hour before and after surgery, and, 1, 2, 4, 6, 12 and 24 hours after the surgery. Results: There was no statistically significant difference between the distributions of sex, type of surgery, and amount of acetaminophen taken after surgery by groups (p values respectively p= 0.245, p=0.994, p=0.131 ). There was a statistically significant difference between the distributions of 4th-hour values VAS by group (p=0.008). There is a statistically significant difference between the groups' distributions of the values of the 6th-hour VAS (p=0.016). VAS scores were lower in the epidural blood patch group. There was no difference between the VAS scores in the blood patch and block group in all other measurement periods. Nevertheless, comparing the time variables of the groups, the main effect of time has a statistically significant impact on the VAS (p < 0.001). There was a significant difference in the sphenopalatine ganglion block and epidural blood patch groups when the pre-surgery VAS value was compared with all post-surgery periods (p < 0.001, p < 0.001). Conclusion: The epidural blood patch is the gold standard in treating postspinal headaches. However, it is a difficult procedure to perform since it is an invasive procedure. Sphenopalatine ganglion blockade is a treatment modality with very close efficacy to epidural blood patches in treating postspinal headaches. It can be used as an alternative treatment method in cases that do not accept treatment with the epidural blood patch. As postspinal headache mostly occurs in obstetrics patients, it can be safely used to protect a newborn mother and the baby from the side effects of drugs that pass into the breast milk.
目的:脊髓穿刺后头痛(PDPH)影响术后恢复和患者的生活质量。PDPH是脊髓麻醉最常见的并发症，对患者的健康影响最大。硬膜外血贴(EBP)是介入治疗PDPH的金标准。蝶腭神经节阻滞(SPGB)是一种新的无创治疗PDPH的方法。与EBP相比，SPGB无创，操作简便。本研究旨在比较两种介入治疗PDPH的疗效。材料与方法:2018年1月1日至2023年2月1日，30例诊断为PDPH的患者行EBP和28例SPGB。记录病例统计资料、手术类型、术后是否发生并发症以及24小时内对乙酰氨基酚的用量(mg)。分别于术前、术后半小时及术后1、2、4、6、12、24小时分别记录VAS评分8次。结果:各组患者性别、手术类型、术后对乙酰氨基酚用量分布差异无统计学意义(p值分别为p= 0.245、p=0.994、p=0.131)。各组间第4小时VAS值分布差异有统计学意义(p=0.008)。两组患者第6小时VAS评分分布差异有统计学意义(p=0.016)。硬膜外血贴片组VAS评分较低。血液贴片组和阻断组的VAS评分在其他所有测量期间均无差异。然而，比较各组的时间变量，时间的主效应对VAS的影响具有统计学意义(p <0.001)。术前VAS值与术后各期比较，蝶腭神经节阻滞组和硬膜外血贴组差异有统计学意义(p <0.001, p <0.001)。结论:硬膜外补血是治疗脊柱后头痛的金标准。然而，由于它是一种侵入性手术，因此很难执行。蝶腭神经节阻滞是一种与硬膜外血贴治疗脊髓后头痛疗效相近的治疗方式。在不接受硬膜外血贴治疗的病例中，它可以作为一种替代治疗方法。由于脊髓后头痛主要发生在产科患者中，它可以安全地用于保护新生儿母亲和婴儿免受药物进入母乳的副作用。
{"title":"Comparison of the Efficacy of Epidural Blood Patch and Transnasal Sphenopalatine Ganglion Block in the Treatment of Postspinal Puncture Headache","authors":"Ebru Canakci, Ilker Coskun","doi":"10.5455/annalsmedres.2023.08.200","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.08.200","url":null,"abstract":"Aim: Postspinal puncture headache (PDPH) affects postoperative recovery and patients' quality of life after surgery. PDPH is the most common complication of spinal anaesthesia that affects patients' well-being the most. The epidural blood patch (EBP) is the gold standard for interventional treatment of PDPH. Sphenopalatine ganglion block (SPGB), a new noninvasive method for treating PDPH, has come to the forefront. SPGB is noninvasive and very easy to perform compared with EBP. This study aims to compare the efficacy of the two interventional methods in treating PDPH. Material and Method: Between January 1, 2018, and February 1, 2023, 30 cases diagnosed with PDPH underwent EBP and 28 SPGB. Case demographics, type of surgery performed, whether complications occurred after the procedure, and the amount of acetaminophen taken within 24 hours were recorded in mg. The VAS scores were recorded 8 times, in the first half hour before and after surgery, and, 1, 2, 4, 6, 12 and 24 hours after the surgery. Results: There was no statistically significant difference between the distributions of sex, type of surgery, and amount of acetaminophen taken after surgery by groups (p values respectively p= 0.245, p=0.994, p=0.131 ). There was a statistically significant difference between the distributions of 4th-hour values VAS by group (p=0.008). There is a statistically significant difference between the groups' distributions of the values of the 6th-hour VAS (p=0.016). VAS scores were lower in the epidural blood patch group. There was no difference between the VAS scores in the blood patch and block group in all other measurement periods. Nevertheless, comparing the time variables of the groups, the main effect of time has a statistically significant impact on the VAS (p < 0.001). There was a significant difference in the sphenopalatine ganglion block and epidural blood patch groups when the pre-surgery VAS value was compared with all post-surgery periods (p < 0.001, p < 0.001). Conclusion: The epidural blood patch is the gold standard in treating postspinal headaches. However, it is a difficult procedure to perform since it is an invasive procedure. Sphenopalatine ganglion blockade is a treatment modality with very close efficacy to epidural blood patches in treating postspinal headaches. It can be used as an alternative treatment method in cases that do not accept treatment with the epidural blood patch. As postspinal headache mostly occurs in obstetrics patients, it can be safely used to protect a newborn mother and the baby from the side effects of drugs that pass into the breast milk.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135839412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.09.251
H L, Elif M, Zekayi KUTLUBAY
Objective: It is suggested that different formulations of botulinum toxin-A (BoNT-A) used for the same indication might be a factor affecting patient satisfaction. This study aimed to assess patient satisfaction levels in treating upper facial wrinkles (UFW) using various BoNT-A formulations and their association with age and gender. Materials and Methods: This retrospective study included 600 UFW patients treated with different formulations of BoNT-A. The BoNT-A formulations included three different groups: onaBoNT-A (ONA, n:200), aboBoNT-A (ABO, n:200), and praBoNT-A (PRA, n:200).In the patient files or records, satisfaction levels from the BoNT-A application were scored as follows: 1: not satisfied, 2: slightly satisfied, 3: satisfied, 4: very satisfied, 5: completely satisfied. Results: The mean patient satisfaction scores were similar in the ONA and ABO groups, but higher in the PRA group (4.4±0.5 vs. 4.3±0.6 vs. 4.0±0.9, P <0.001, respectively). The mean satisfaction score of the patients aged 18-30 and those aged >60 were lower than the other age groups. Among all patients in the 41-50 age range, the patient satisfaction score was higher in the ONA group than the ABO and PRA group. In all female patients, the mean satisfaction score was lower in the PRA group compared to the ONA and ABO groups (P <0.001), Conclusions: While various BoNT-A formulations are generally associated with high patient satisfaction in the treatment of UFW, this can vary depending on age ranges and gender. Evaluating patient-related factors such as age and gender can contribute to the treatment planning for UFW and enhancing treatment adherence.
{"title":"Botulinum toxin-A in the treatment of upper facial wrinkles: efficacy comparison of different formulations","authors":"H L, Elif M, Zekayi KUTLUBAY","doi":"10.5455/annalsmedres.2023.09.251","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.09.251","url":null,"abstract":"Objective: It is suggested that different formulations of botulinum toxin-A (BoNT-A) used for the same indication might be a factor affecting patient satisfaction. This study aimed to assess patient satisfaction levels in treating upper facial wrinkles (UFW) using various BoNT-A formulations and their association with age and gender. Materials and Methods: This retrospective study included 600 UFW patients treated with different formulations of BoNT-A. The BoNT-A formulations included three different groups: onaBoNT-A (ONA, n:200), aboBoNT-A (ABO, n:200), and praBoNT-A (PRA, n:200).In the patient files or records, satisfaction levels from the BoNT-A application were scored as follows: 1: not satisfied, 2: slightly satisfied, 3: satisfied, 4: very satisfied, 5: completely satisfied. Results: The mean patient satisfaction scores were similar in the ONA and ABO groups, but higher in the PRA group (4.4±0.5 vs. 4.3±0.6 vs. 4.0±0.9, P <0.001, respectively). The mean satisfaction score of the patients aged 18-30 and those aged >60 were lower than the other age groups. Among all patients in the 41-50 age range, the patient satisfaction score was higher in the ONA group than the ABO and PRA group. In all female patients, the mean satisfaction score was lower in the PRA group compared to the ONA and ABO groups (P <0.001), Conclusions: While various BoNT-A formulations are generally associated with high patient satisfaction in the treatment of UFW, this can vary depending on age ranges and gender. Evaluating patient-related factors such as age and gender can contribute to the treatment planning for UFW and enhancing treatment adherence.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134981023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.03.065
S. Keser, S. Kobat, E. Yusufoğlu, Fatma Savur, Sara Koylu Gungor
{"title":"AN EXAMINATION OF THE OCULAR SURFACE PARAMETERS OF PATIENTS WITH NON-EXOPHTHALMIC GRAVES DISEASE","authors":"S. Keser, S. Kobat, E. Yusufoğlu, Fatma Savur, Sara Koylu Gungor","doi":"10.5455/annalsmedres.2023.03.065","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.03.065","url":null,"abstract":"<jats:p />","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78257058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.04.083
O. Ekinci, Fadime ay, Al Koyuncu, Feyza Soy, Or etin, Feyza ce
Objective: The present study aimed to examine possible relationships between suicide-related terms obtained from Google Trends and actual suicide data and whether these relationships differ according to sex. Materials and Methods: The study period was from 2009 to 2019. In this study, suicide data were collected from the suicide statistics of the Turkish Statistical Institute (TUIK) for this timeframe. Google Trends was used to examine the search trends of suicide-related terms in Turkey. Pearson correlation analysis was used to find associations between the data obtained from TUIK and Google Trends. Finally, linear regression analysis was performed to identify predictors of monthly completed suicide rates in the general population. Results: In our study, 105 search terms obtained from Google Trends were examined to find associations with suicide rates in a specific timeframe. Among them, 31 terms had positive correlations, and nine had significant negative correlations. The terms "allergy" and "pain" were the most closely related to the overall suicide rates. Other significantly correlated terms were "how to commit suicide," "to commit suicide," "depression," and "hallucination." In addition, significantly different results were found for men and women. Conclusion: The present study showed that suicide-related terms obtained from Google Trends may predict actual suicide rates and may be an easy way to monitor suicide trends in Turkey. Future studies should use a more comprehensive internet network, including social media and other search engines, and consider other variables related to suicide to better understand this relationship.
{"title":"Assessment of the relationship between Google Trends search data and national suicide rates in Turkey","authors":"O. Ekinci, Fadime ay, Al Koyuncu, Feyza Soy, Or etin, Feyza ce","doi":"10.5455/annalsmedres.2023.04.083","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.04.083","url":null,"abstract":"Objective: The present study aimed to examine possible relationships between suicide-related terms obtained from Google Trends and actual suicide data and whether these relationships differ according to sex. Materials and Methods: The study period was from 2009 to 2019. In this study, suicide data were collected from the suicide statistics of the Turkish Statistical Institute (TUIK) for this timeframe. Google Trends was used to examine the search trends of suicide-related terms in Turkey. Pearson correlation analysis was used to find associations between the data obtained from TUIK and Google Trends. Finally, linear regression analysis was performed to identify predictors of monthly completed suicide rates in the general population. Results: In our study, 105 search terms obtained from Google Trends were examined to find associations with suicide rates in a specific timeframe. Among them, 31 terms had positive correlations, and nine had significant negative correlations. The terms \"allergy\" and \"pain\" were the most closely related to the overall suicide rates. Other significantly correlated terms were \"how to commit suicide,\" \"to commit suicide,\" \"depression,\" and \"hallucination.\" In addition, significantly different results were found for men and women. Conclusion: The present study showed that suicide-related terms obtained from Google Trends may predict actual suicide rates and may be an easy way to monitor suicide trends in Turkey. Future studies should use a more comprehensive internet network, including social media and other search engines, and consider other variables related to suicide to better understand this relationship.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74893100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.04.094
A. M. Res, S. Kandemir, G. Pamuk, T. Yi̇ği̇t
{"title":"Evaluation of the necessity of routine histopathological examination in tonsillectomy and/or adenoidectomy operations. Histopathology of tonsillectomy and/or adenoidectomy","authors":"A. M. Res, S. Kandemir, G. Pamuk, T. Yi̇ği̇t","doi":"10.5455/annalsmedres.2023.04.094","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.04.094","url":null,"abstract":"<jats:p />","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75760218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.03.068
Emine Y lmaz
Objective: Non-melanoma skin cancer (NMSC) is the most prevalent malignancy worldwide, with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) representing the most common types of NMSC. In this retrospective analysis, patients with NMSC who had adjuvant radiotherapy (RT) had their treatment results and prognostic variables evaluated. Material and Methods: A total of 115 patients with NMSC who had adjuvant RT in our clinic during January 2006 and September 2021 were assessed. The average age was 74 years, and the male to female ratio was 1.95:1. (range: 25–95). The most often diagnosed kind of NMSC was SCC (93%, n=107), preceded by BCC (7%, n=8). The extremities (17.4%, n=20), the trunk (1.7%, n=2), and the head and neck area (80.9%, n=93) were where the bulk of NMSC lesions were discovered. Results: The mean follow-up period was 60.7 months (the range was 4.2–194.7); metastases were found in six patients (5.2%), and locoregional recurrence was identified in 24 patients (20.8%). The 3- and 5-year total survival percentages were 71.2% and 59.3%, respectively, and the median overall survival (OS) time was 87.1 months. Tumor size and surgical margin status were linked to a worse OS in multivariate analysis of prognostic variables (hazard rate [HR]=3.0, 95% confidence interval [CI]: 1.8-5.2; p=0,001 and HR=2.4, 95% CI: 1.4-4.1; P=0,002, respectively). Conclusion: Postoperative RT is an efficient, acceptable therapeutic option for NMSC in high-risk individuals. Our results suggest that surgical margin and tumor size were independent predictors of OS in NMSC patients; nevertheless, future studies including more patients are required to corroborate these results.
{"title":"Prognostic factors and the role of adjuvant radiation therapy in Non-melanoma skin cancer: Retrospective, A single-center experience","authors":"Emine Y lmaz","doi":"10.5455/annalsmedres.2023.03.068","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.03.068","url":null,"abstract":"Objective: Non-melanoma skin cancer (NMSC) is the most prevalent malignancy worldwide, with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) representing the most common types of NMSC. In this retrospective analysis, patients with NMSC who had adjuvant radiotherapy (RT) had their treatment results and prognostic variables evaluated. Material and Methods: A total of 115 patients with NMSC who had adjuvant RT in our clinic during January 2006 and September 2021 were assessed. The average age was 74 years, and the male to female ratio was 1.95:1. (range: 25–95). The most often diagnosed kind of NMSC was SCC (93%, n=107), preceded by BCC (7%, n=8). The extremities (17.4%, n=20), the trunk (1.7%, n=2), and the head and neck area (80.9%, n=93) were where the bulk of NMSC lesions were discovered. Results: The mean follow-up period was 60.7 months (the range was 4.2–194.7); metastases were found in six patients (5.2%), and locoregional recurrence was identified in 24 patients (20.8%). The 3- and 5-year total survival percentages were 71.2% and 59.3%, respectively, and the median overall survival (OS) time was 87.1 months. Tumor size and surgical margin status were linked to a worse OS in multivariate analysis of prognostic variables (hazard rate [HR]=3.0, 95% confidence interval [CI]: 1.8-5.2; p=0,001 and HR=2.4, 95% CI: 1.4-4.1; P=0,002, respectively). Conclusion: Postoperative RT is an efficient, acceptable therapeutic option for NMSC in high-risk individuals. Our results suggest that surgical margin and tumor size were independent predictors of OS in NMSC patients; nevertheless, future studies including more patients are required to corroborate these results.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"149 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79391280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2022.09.281
A. M. Res, C. Gunbey, H. Aykan, T. Karagoz, G. Turanlı, M. Topçu, D. Yalnızoǧlu
Objective: In children, a broad range of paroxysmal events, including syncope and arrhythmias, may mimic true epileptic seizures. When a definitive diagnosis could not be established, long-term video electroencephalogram monitoring (LTVEM) should be taken into consideration. Furthermore, epilepsy patients have a higher rate of cardiac comorbidities. The purpose of this study is to evaluate the rationale and results of the pediatric cardiology consultations in patients admitted to the LTVEM unit. Methods: We retrospectively analyzed the files of children who were admitted to LTVEM unit and consulted with the pediatric cardiology department between January 2006 and May 2014. The patients who had both echocardiography and 24-hour ambulatory electrocardiogram monitoring were included. Results: Among 70 children, 74.3% (n: 52) were classified as having epilepsy, 21.4%. (n: 15) with nonepileptic events, and 4.3% (n: 3) could not be classified. In epilepsy group, 21 children (40.4%) were consulted with pediatric cardiology due to rhythm disturbances detected during LTVEM, the remaining consultations (59.6%) were due to history of known cardiac diagnosis (arrythmias n: 2, structural/congenital heart disease: 5), tuberosclerosis (n: 6), drop attacks (n: 5), murmur (n: 5), and other reasons. The cardiac evaluation revealed previously undetected arrhythmia (n:3) and mitral valve prolapse (n:1) in four patients with epilepsy. In addition to the pre-existing long QT syndrome, one child experienced his typical attack, subsequently he was diagnosed as epilepsy. The remaining group consisted of 18 children, with syncope being the most common diagnosis for consultation (n: 10, 55.5%). Conclusion: Our study revealed that a subgroup of children with epilepsy had cardiovascular comorbidities. Additionally, epilepsy was confirmed in some patients who already had cardiac problems. Pediatricians should be aware of potential mimickers of epilepsy and note that epilepsy and cardiac problems may also co-exist. Correct diagnosis and appropriate treatment are crucial in this patient group.
{"title":"Pediatric Cardiology Consultation at Long-Term Video EEG Monitoring","authors":"A. M. Res, C. Gunbey, H. Aykan, T. Karagoz, G. Turanlı, M. Topçu, D. Yalnızoǧlu","doi":"10.5455/annalsmedres.2022.09.281","DOIUrl":"https://doi.org/10.5455/annalsmedres.2022.09.281","url":null,"abstract":"Objective: In children, a broad range of paroxysmal events, including syncope and arrhythmias, may mimic true epileptic seizures. When a definitive diagnosis could not be established, long-term video electroencephalogram monitoring (LTVEM) should be taken into consideration. Furthermore, epilepsy patients have a higher rate of cardiac comorbidities. The purpose of this study is to evaluate the rationale and results of the pediatric cardiology consultations in patients admitted to the LTVEM unit. Methods: We retrospectively analyzed the files of children who were admitted to LTVEM unit and consulted with the pediatric cardiology department between January 2006 and May 2014. The patients who had both echocardiography and 24-hour ambulatory electrocardiogram monitoring were included. Results: Among 70 children, 74.3% (n: 52) were classified as having epilepsy, 21.4%. (n: 15) with nonepileptic events, and 4.3% (n: 3) could not be classified. In epilepsy group, 21 children (40.4%) were consulted with pediatric cardiology due to rhythm disturbances detected during LTVEM, the remaining consultations (59.6%) were due to history of known cardiac diagnosis (arrythmias n: 2, structural/congenital heart disease: 5), tuberosclerosis (n: 6), drop attacks (n: 5), murmur (n: 5), and other reasons. The cardiac evaluation revealed previously undetected arrhythmia (n:3) and mitral valve prolapse (n:1) in four patients with epilepsy. In addition to the pre-existing long QT syndrome, one child experienced his typical attack, subsequently he was diagnosed as epilepsy. The remaining group consisted of 18 children, with syncope being the most common diagnosis for consultation (n: 10, 55.5%). Conclusion: Our study revealed that a subgroup of children with epilepsy had cardiovascular comorbidities. Additionally, epilepsy was confirmed in some patients who already had cardiac problems. Pediatricians should be aware of potential mimickers of epilepsy and note that epilepsy and cardiac problems may also co-exist. Correct diagnosis and appropriate treatment are crucial in this patient group.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84876967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/annalsmedres.2023.06.135
Zeynep nal, Z. Bahtiyarca, D. Cankurtaran, Ece z
Aim: It was aimed to evaluate the characteristics of the patients who were referred to our electroneuromiyography (ENMG) Laboratory to evaluate the rate of locomotor system disability from the Disabled Health Board (DMB). Materials and Methods: Patients aged 18 years and over who applied to our hospital's DMB in the last three years (01.01.2019-31.12.2021) and were referred to the ENMG Laboratory to determine the disability rates related to the locomotor system were included. With the retrospective analysis, demographic characteristics of the patients, ambulatory levels, etiological factors, reasons for applying to the ENMG Laboratory, and diagnoses in ENMG reports were noted. Results: Files of 1306 patients were reviewed, ENMG was performed in 139 (10.64%). The mean age was 45.34±12.2 years. One-hundred and eleven (79.9%) patients were male and 28 (20.21%) were female. Eighteen (12.9%) of the patients needed an assistive walking device. The most common etiological factors in locomotor system disability was disc herniation in 24 (17.2%) patients. The most common preliminary diagnosis was peripheral nerve injury in 67 (48.2%) patients. Peripheral nerve injury was the most frequently reported pathology in ENMG reports with 52 (37.4%) patients. While the ENMG report of 26 (18.7%) patients was normal; entrapment neuropathy was found in 14 (10.1%) patients, polyneuropathy in 10 (7.2%) patients, plexopathy in 8 (5.8%) patients, and cranial neuropathy in 1 (0.7%) patient. Conclusion: Peripheral nerve injuries are the most common pathology in both preliminary diagnosis and ENMG reports. ENMG provides information such as the location and the severity of the lesion, so electrodiagnostic tests are very important in the evaluation of locomotor system disability.
{"title":"The Rate of Locomotor System Disability in Patients Undergoing Electroneuromyography","authors":"Zeynep nal, Z. Bahtiyarca, D. Cankurtaran, Ece z","doi":"10.5455/annalsmedres.2023.06.135","DOIUrl":"https://doi.org/10.5455/annalsmedres.2023.06.135","url":null,"abstract":"Aim: It was aimed to evaluate the characteristics of the patients who were referred to our electroneuromiyography (ENMG) Laboratory to evaluate the rate of locomotor system disability from the Disabled Health Board (DMB). Materials and Methods: Patients aged 18 years and over who applied to our hospital's DMB in the last three years (01.01.2019-31.12.2021) and were referred to the ENMG Laboratory to determine the disability rates related to the locomotor system were included. With the retrospective analysis, demographic characteristics of the patients, ambulatory levels, etiological factors, reasons for applying to the ENMG Laboratory, and diagnoses in ENMG reports were noted. Results: Files of 1306 patients were reviewed, ENMG was performed in 139 (10.64%). The mean age was 45.34±12.2 years. One-hundred and eleven (79.9%) patients were male and 28 (20.21%) were female. Eighteen (12.9%) of the patients needed an assistive walking device. The most common etiological factors in locomotor system disability was disc herniation in 24 (17.2%) patients. The most common preliminary diagnosis was peripheral nerve injury in 67 (48.2%) patients. Peripheral nerve injury was the most frequently reported pathology in ENMG reports with 52 (37.4%) patients. While the ENMG report of 26 (18.7%) patients was normal; entrapment neuropathy was found in 14 (10.1%) patients, polyneuropathy in 10 (7.2%) patients, plexopathy in 8 (5.8%) patients, and cranial neuropathy in 1 (0.7%) patient. Conclusion: Peripheral nerve injuries are the most common pathology in both preliminary diagnosis and ENMG reports. ENMG provides information such as the location and the severity of the lesion, so electrodiagnostic tests are very important in the evaluation of locomotor system disability.","PeriodicalId":8248,"journal":{"name":"Annals of Medical Research","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84546342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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