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The Influence of Physiological Blood Clot on Osteoblastic Cell Response to a Chitosan-Based 3D Scaffold-A Pilot Investigation. 生理性血凝块对成骨细胞对壳聚糖3D支架反应的影响- a先导研究。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-21 DOI: 10.3390/biomimetics9120782
Natacha Malu Miranda da Costa, Hilary Ignes Palma Caetano, Larissa Miranda Aguiar, Ludovica Parisi, Benedetta Ghezzi, Lisa Elviri, Leonardo Raphael Zuardi, Paulo Tambasco de Oliveira, Daniela Bazan Palioto

Background: The use of ex vivo assays associated with biomaterials may allow the short-term visualization of a specific cell type response inserted in a local microenvironment. Blood is the first component to come into contact with biomaterials, providing blood clot formation, being substantial in new tissue formation. Thus, this research investigated the physiological blood clot (PhC) patterns formed in 3D scaffolds (SCAs), based on chitosan and 20% beta-tricalcium phosphate and its effect on osteogenesis. Initially, SCA were inserted for 16 h in rats calvaria defects, and, after that, osteoblasts cells (OSB; UMR-106 lineage) were seeded on the substrate formed. The groups tested were SCA + OSB and SCA + PhC + OSB. Cell viability was checked by MTT and mineralized matrix formation in OSB using alizarin red (ARS). The alkaline phosphatase (ALP) and bone sialoprotein (BSP) expression in OSB was investigated by indirect immunofluorescence (IF). The OSB and PhC morphology was verified by scanning electron microscopy (SEM).

Results: The SCA + PhC + OSB group showed greater cell viability (p = 0.0169). After 10 days, there was more mineralized matrix deposition (p = 0.0365) and high ALP immunostaining (p = 0.0021) in the SCA + OSB group. In contrast, BSP was more expressed in OSB seeded on SCA with PhC (p = 0.0033).

Conclusions: These findings show the feasibility of using PhC in ex vivo assays. Additionally, its inclusion in the experiments resulted in a change in OSB behavior when compared to in vitro assays. This "closer to nature" environment can completely change the scenario of a study.

背景:与生物材料相关的离体试验的使用可能允许在局部微环境中插入特定细胞类型反应的短期可视化。血液是第一个与生物材料接触的成分,提供血栓形成,在新组织形成中是重要的。因此,本研究探讨了壳聚糖和20%磷酸三钙在3D支架(SCAs)中形成的生理性血凝块(PhC)模式及其对成骨的影响。首先,将SCA植入大鼠颅骨缺损16小时,之后,将成骨细胞(OSB;UMR-106谱系)被播种在形成的底物上。试验分为SCA + OSB组和SCA + PhC + OSB组。MTT法检测细胞活力,茜素红(ARS)法检测OSB矿化基质形成。采用间接免疫荧光法(IF)检测碱性磷酸酶(ALP)和骨唾液蛋白(BSP)在OSB组织中的表达。通过扫描电镜(SEM)验证了OSB和PhC的形貌。结果:SCA + PhC + OSB组细胞活力显著提高(p = 0.0169)。10 d后,SCA + OSB组矿化基质沉积较多(p = 0.0365), ALP免疫染色较高(p = 0.0021)。相比之下,PhC在SCA上播种的OSB中BSP的表达量更高(p = 0.0033)。结论:这些结果表明PhC在离体实验中是可行的。此外,与体外实验相比,将其纳入实验导致OSB行为发生变化。这种“更接近自然”的环境可以完全改变研究的场景。
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引用次数: 0
Trajectory Tracking Control for Robotic Manipulator Based on Soft Actor-Critic and Generative Adversarial Imitation Learning. 基于软行为批评和生成对抗模仿学习的机械臂轨迹跟踪控制。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-21 DOI: 10.3390/biomimetics9120779
Jintao Hu, Fujie Wang, Xing Li, Yi Qin, Fang Guo, Ming Jiang

In this paper, a deep reinforcement learning (DRL) approach based on generative adversarial imitation learning (GAIL) and long short-term memory (LSTM) is proposed to resolve tracking control problems for robotic manipulators with saturation constraints and random disturbances, without learning the dynamic and kinematic model of the manipulator. Specifically, it limits the torque and joint angle to a certain range. Firstly, in order to cope with the instability problem during training and obtain a stability policy, soft actor-critic (SAC) and LSTM are combined. The changing trends of joint position over time are more comprehensively captured and understood by employing an LSTM architecture designed for robotic manipulator systems, thereby reducing instability during the training of robotic manipulators for tracking control tasks. Secondly, the obtained policy by SAC-LSTM is used as expert data for GAIL to learn a better control policy. This SAC-LSTM-GAIL (SL-GAIL) algorithm does not need to spend time exploring unknown environments and directly learns the control strategy from stable expert data. Finally, it is demonstrated by the simulation results that the end effector of the robot tracking task is effectively accomplished by the proposed SL-GAIL algorithm, and more superior stability is exhibited in a test environment with interference compared with other algorithms.

本文提出了一种基于生成对抗模仿学习(GAIL)和长短期记忆(LSTM)的深度强化学习(DRL)方法,在不学习机械臂动力学和运动学模型的情况下,解决了具有饱和约束和随机干扰的机械臂跟踪控制问题。具体而言,它将扭矩和关节角度限制在一定范围内。首先,为了解决训练过程中的不稳定性问题并获得稳定策略,将软行为者批评(SAC)与LSTM相结合;通过采用针对机械手系统设计的LSTM体系结构,可以更全面地捕捉和理解关节位置随时间的变化趋势,从而减少机械手跟踪控制任务训练过程中的不稳定性。其次,将SAC-LSTM获得的策略作为GAIL的专家数据来学习更好的控制策略。这种SAC-LSTM-GAIL (SL-GAIL)算法不需要花费时间探索未知环境,直接从稳定的专家数据中学习控制策略。最后,仿真结果表明,所提出的SL-GAIL算法能够有效地完成机器人末端执行器的跟踪任务,并且在有干扰的测试环境中比其他算法表现出更优越的稳定性。
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引用次数: 0
Biomimetic Linkage Mechanism Robust Control for Variable Stator Vanes in Aero-Engine. 航空发动机可变定子叶片仿生连杆机构鲁棒控制。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-21 DOI: 10.3390/biomimetics9120778
Qinqin Sun, Zhangyang Lu, Xingyu Gui, Ye-Hwa Chen

This work addresses the position tracking control design of the stator vane driven by electro-hydrostatic actuators facing uncertain aerodynamic disturbances. Rapidly changing aerodynamic conditions impose complex disturbance torques on the guide vanes. Consequently, a challenging task is to enhance control precision in complex uncertain environments. Inspired by the principles of mammalian muscle movement, a novel robust control strategy based on the backstepping method has been proposed. Using backstepping, virtual rotational speed and virtual pressure difference force are designed, which decompose the high-order position closed-loop control problem into three lower-order parts, eliminating the need for matching conditions. Subsequently, robust controllers were designed, and stability proofs and performance analyses of the controllers were provided. This control strategy was tested through numerical hydraulic simulation. The results show that compared to other control methods, this approach significantly improves tracking accuracy and robustness. Therefore, it is believed that this method has the potential to become a new generation solution for such problems.

本文研究了在不确定气动干扰下,由电静液作动器驱动的静叶位置跟踪控制设计。快速变化的气动条件对导叶施加了复杂的扰动力矩。因此,如何提高复杂不确定环境下的控制精度是一项具有挑战性的任务。受哺乳动物肌肉运动原理的启发,提出了一种基于反推法的鲁棒控制策略。采用反推法设计了虚拟转速和虚拟压差力,将高阶位置闭环控制问题分解为三个低阶部分,消除了匹配条件的需要。随后,设计了鲁棒控制器,并给出了控制器的稳定性证明和性能分析。通过数值液压仿真对该控制策略进行了验证。结果表明,与其他控制方法相比,该方法显著提高了跟踪精度和鲁棒性。因此,相信该方法有可能成为解决此类问题的新一代解决方案。
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引用次数: 0
Insight into the Use of Brewers' Spent Grain as a Low-Carbon Aggregate in Building Materials. 啤酒酿造者的废粮作为低碳骨料用于建筑材料的洞察。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-21 DOI: 10.3390/biomimetics9120781
Badreddine El Haddaji, Mohammed-Hichem Benzaama, Marc Quiertant, Yassine El Mendili

This study investigates the use of Brewers' Spent Grains (BSGs) as a sustainable biocomposite building materials, using cornstarch as a biopolymer binder. BSG aggregates are compared with hemp shives, a conventional aggregate known for its thermal properties. Starch is employed as a natural binder in three different formulations to further reduce the carbon footprint of the building material. Considering aggregates, the first formulation contains only BSGs, the second consists of half BSGs and half hemp shives, and the third uses only hemp shives. In addition, morphological analysis using Scanning Electron Microscopy (SEM) is conducted to examine the microstructure and porosity of the raw BSG and hemp shives. Hygrothermal properties are measured using Heat Flow Meter (HFM) and Dynamic Vapor Sorption (DVS) techniques, while mechanical properties are also assessed. Results indicate that the thermal conductivity of the BSG formulation (0.131 W/(m·K)) is double that of the hemp shives formulation (0.067 W/(m·K)), whereas the mixed BSG/hemp shives formulation exhibits a thermal conductivity of 0.106 W/(m·K). However, DVS measurements reveal better hygrothermal properties for the BSG formulation compared to the hemp shives formulation. Lastly, mechanical properties are found to be nearly equivalent across the three formulations. These findings suggest that BSG waste has potential as a viable material for use in construction. Further work on formulation optimization and durability is necessary to fully realize the potential of this waste in promoting a circular economy within the building materials industry.

本研究以玉米淀粉为生物聚合物粘结剂,研究了啤酒糟(BSGs)作为可持续生物复合建筑材料的使用。BSG骨料与大麻屑相比,传统骨料以其热性能而闻名。淀粉被用作三种不同配方的天然粘合剂,以进一步减少建筑材料的碳足迹。考虑到骨料,第一种配方仅含有BSGs,第二种配方由一半BSGs和一半大麻片组成,第三种配方仅使用大麻片。此外,利用扫描电子显微镜(SEM)进行了形态学分析,以检查原料BSG和大麻片的微观结构和孔隙率。使用热流计(HFM)和动态蒸汽吸收(DVS)技术测量湿热性能,同时也评估机械性能。结果表明,BSG配方的导热系数为0.131 W/(m·K),是大麻片配方(0.067 W/(m·K))的两倍,而BSG/大麻片混合配方的导热系数为0.106 W/(m·K)。然而,DVS测量显示更好的湿热性能的BSG制剂相比,大麻屑制剂。最后,发现力学性能在三种配方中几乎相等。这些发现表明,BSG废物有潜力作为一种可行的材料用于建筑。为了充分发挥这种废物在促进建筑材料行业循环经济方面的潜力,有必要进一步开展配方优化和耐用性方面的工作。
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引用次数: 0
Kinematics and Flow Field Analysis of Allomyrina dichotoma Flight. 异蝇双歧飞行器运动学及流场分析。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-20 DOI: 10.3390/biomimetics9120777
Huan Shen, Kai Cao, Chao Liu, Zhiyuan Mao, Qian Li, Qingfei Han, Yi Sun, Zhikang Yang, Youzhi Xu, Shutao Wu, Jiajun Xu, Aihong Ji

In recent years, bioinspired insect flight has become a prominent research area, with a particular focus on beetle-inspired aerial vehicles. Studying the unique flight mechanisms and structural characteristics of beetles has significant implications for the optimization of biomimetic flying devices. Among beetles, Allomyrina dichotoma (rhinoceros beetle) exhibits a distinct wing deployment-flight-retraction sequence, whereby the interaction between the hindwings and protective elytra contributes to lift generation and maintenance. This study investigates A. dichotoma's wing deployment, flight, and retraction behaviors through motion analysis, uncovering the critical role of the elytra in wing folding. We capture the kinematic parameters throughout the entire flight process and develop an accurate kinematic model of A. dichotoma flight. Using smoke visualization, we analyze the flow field generated during flight, revealing the formation of enhanced leading-edge vortices and attached vortices during both upstroke and downstroke phases. These findings uncover the high-lift mechanism underlying A. dichotoma's flight dynamics, offering valuable insights for optimizing beetle-inspired micro aerial vehicles.

近年来,生物昆虫飞行已成为一个突出的研究领域,特别是甲虫启发的飞行器。研究甲虫独特的飞行机制和结构特征对仿生飞行装置的优化具有重要意义。在甲虫中,异角角甲虫(Allomyrina dichotoma, rhinoceros beetle)表现出独特的翅膀展开-飞行-收缩的顺序,即后翅和鞘翅之间的相互作用有助于升力的产生和维持。本研究通过运动分析研究了双翅翅的展开、飞行和缩回行为,揭示了鞘翅在翅膀折叠中的关键作用。我们捕获了整个飞行过程中的运动学参数,并建立了精确的双歧蝽飞行运动学模型。利用烟雾可视化技术,我们分析了飞行过程中产生的流场,揭示了在上冲程和下冲程阶段增强前缘涡和附加涡的形成。这些发现揭示了A. dichotoma飞行动力学背后的高升力机制,为优化甲虫启发的微型飞行器提供了有价值的见解。
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引用次数: 0
A Worm-like Soft Robot Based on Adhesion-Controlled Electrohydraulic Actuators. 基于黏附控制电液作动器的蠕虫状软体机器人。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-20 DOI: 10.3390/biomimetics9120776
Yangzhuo Wu, Zhe Sun, Yu Xiang, Jieliang Zhao

Worms are organisms characterized by simple structures, low energy consumption, and stable movement. Inspired by these characteristics, worm-like soft robots demonstrate exceptional adaptability to unstructured environments, attracting considerable interest in the field of biomimetic engineering. The primary challenge currently involves improving the motion performance of worm-like robots from the perspectives of actuation and anchoring. In this study, a single segment worm-like soft robot driven by electrohydraulic actuators is proposed. The robot consists of a soft actuation module and two symmetrical anchoring modules. The actuation modules enable multi-degree-of-freedom motion of the robot using symmetric dual-electrode electrohydraulic actuators, while the anchoring modules provide active friction control through bistable electrohydraulic actuators. A hierarchical microstructure design is used for the biomimetic adhesive surface, enabling rapid, reversible, and stable attachment to and detachment from different surfaces, thereby improving the robot's surface anchoring performance. Experimental results show that the designed robot can perform peristaltic and bending motions similar to a worm. It achieves rapid bidirectional propulsion on both dry and wet surfaces, with a maximum speed of 10.36 mm/s (over 6 velocity/length ratio (min-1)).

蠕虫是一种结构简单、能量消耗低、运动稳定的生物。受这些特性的启发,蠕虫类软体机器人表现出对非结构化环境的卓越适应性,引起了仿生工程领域的极大兴趣。目前的主要挑战是从驱动和锚定的角度来改进类蠕虫机器人的运动性能。本文提出了一种由电液作动器驱动的单节类蠕虫软机器人。该机器人由一个软驱动模块和两个对称的锚定模块组成。驱动模块采用对称双电极电液致动器实现机器人多自由度运动,锚定模块采用双稳态电液致动器实现主动摩擦控制。仿生粘接表面采用层次化微结构设计,能够快速、可逆、稳定地附着和脱离不同表面,从而提高机器人的表面锚定性能。实验结果表明,所设计的机器人可以进行类似蠕虫的蠕动和弯曲运动。它可以在干燥和潮湿表面上实现快速双向推进,最大速度为10.36毫米/秒(超过6速度/长度比(min-1))。
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引用次数: 0
An Octopus-Inspired Soft Pneumatic Robotic Arm. 受章鱼启发的柔性气动机械臂。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-19 DOI: 10.3390/biomimetics9120773
Emmanouil Papadakis, Dimitris P Tsakiris, Michael Sfakiotakis

This paper addresses the design, development, control, and experimental evaluation of a soft robot arm whose actuation is inspired by the muscular structure of the octopus arm, one of the most agile biological manipulators. The robot arm is made of soft silicone and thus possesses enhanced compliance, which is beneficial in a variety of applications where the arm may come into contact with delicate features of its environment. The arm is composed of three elongated segments arranged in series, each one of which contains several pneumatically actuated chambers embedded in its silicone body, which may induce various types of deformations of the segment. By combining the segment deformations, and by imitating the antagonistic muscle group functionality of the octopus, the robot arm can bend in various directions, increase or decrease its length, as well as twist around its central axis. This is one of the few octopus-inspired soft robotic arms where twisting is replicated in its motion characteristics, thus greatly expanding the arm's potential applications. We present the design process and the development steps of the soft arm, where the molding of two-part silicone of low hardness in 3d-printed molds is employed. In addition, we present the control methodology and the experimental evaluation of both a standalone segment and the entire three-segment arm. This experimental evaluation involves model-free closed-loop control schemes, exploiting visual feedback from a pair of external cameras in order to reconstruct in real time the shape of the soft arm and the pose of its tip.

本文介绍了一种柔性机械臂的设计、开发、控制和实验评估,该机械臂的驱动灵感来自于最灵活的生物机械臂之一章鱼臂的肌肉结构。机器人手臂由柔软的硅胶制成,因此具有增强的顺应性,这在手臂可能接触其环境的微妙特征的各种应用中是有益的。该机械臂由串联排列的三个细长节段组成,每一个细长节段都包含几个嵌入在其硅胶体内的气动驱动腔室,这些腔室可引起该节段的各种变形。通过结合节段变形,并模仿章鱼的对抗肌群功能,机械臂可以向各个方向弯曲,增加或减少其长度,以及绕其中心轴扭曲。这是为数不多的受章鱼启发的柔性机械臂之一,在其运动特性中复制了扭曲,从而极大地扩展了手臂的潜在应用。本文介绍了柔性手臂的设计过程和开发步骤,其中采用了3d打印模具中低硬度双组份硅胶的成型。此外,我们提出了控制方法和实验评估两个独立段和整个三段手臂。这项实验评估涉及无模型闭环控制方案,利用一对外部摄像机的视觉反馈,以实时重建柔软手臂的形状和尖端的姿势。
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引用次数: 0
Research on Multimodal Control Method for Prosthetic Hands Based on Visuo-Tactile and Arm Motion Measurement. 基于视触觉和手臂运动测量的假手多模态控制方法研究。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-19 DOI: 10.3390/biomimetics9120775
Jianwei Cui, Bingyan Yan

The realization of hand function reengineering using a manipulator is a research hotspot in the field of robotics. In this paper, we propose a multimodal perception and control method for a robotic hand to assist the disabled. The movement of the human hand can be divided into two parts: the coordination of the posture of the fingers, and the coordination of the timing of grasping and releasing objects. Therefore, we first used a pinhole camera to construct a visual device suitable for finger mounting, and preclassified the shape of the object based on YOLOv8; then, a filtering process using multi-frame synthesized point cloud data from miniature 2D Lidar, and DBSCAN algorithm clustering objects and the DTW algorithm, was proposed to further identify the cross-sectional shape and size of the grasped part of the object and realize control of the robot's grasping gesture; finally, a multimodal perception and control method for prosthetic hands was proposed. To control the grasping attitude, a fusion algorithm based on information of upper limb motion state, hand position, and lesser toe haptics was proposed to realize control of the robotic grasping process with a human in the ring. The device designed in this paper does not contact the human skin, does not produce discomfort, and the completion rate of the grasping process experiment reached 91.63%, which indicates that the proposed control method has feasibility and applicability.

利用机械手实现手的功能再造是机器人领域的一个研究热点。在本文中,我们提出了一种多模态感知和控制方法的机械手,以帮助残疾人。人的手的运动可以分为两个部分:手指姿势的协调,以及抓取和释放物体的时机的协调。因此,我们首先使用针孔相机构建适合手指安装的视觉装置,并基于YOLOv8对物体形状进行预分类;然后,利用微型二维激光雷达合成的多帧点云数据进行滤波处理,结合聚类目标的DBSCAN算法和DTW算法,进一步识别物体被抓取部分的横截面形状和大小,实现机器人抓取姿态的控制;最后,提出了一种假手多模态感知与控制方法。为了控制机器人的抓取姿态,提出了一种基于上肢运动状态、手部位置和小脚趾触觉信息的融合算法,实现了机器人在环上抓取过程的控制。本文设计的装置不接触人体皮肤,不产生不适感,抓取过程实验完成率达到91.63%,表明所提出的控制方法具有可行性和适用性。
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引用次数: 0
Dynamic Structure-Aware Modulation Network for Underwater Image Super-Resolution. 水下图像超分辨率动态结构感知调制网络。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-19 DOI: 10.3390/biomimetics9120774
Li Wang, Ke Li, Chengang Dong, Keyong Shen, Yang Mu

Image super-resolution (SR) is a formidable challenge due to the intricacies of the underwater environment such as light absorption, scattering, and color distortion. Plenty of deep learning methods have provided a substantial performance boost for SR. Nevertheless, these methods are not only computationally expensive but also often lack flexibility in adapting to severely degraded image statistics. To counteract these issues, we propose a dynamic structure-aware modulation network (DSMN) for efficient and accurate underwater SR. A Mixed Transformer incorporated a structure-aware Transformer block and multi-head Transformer block, which could comprehensively utilize local structural attributes and global features to enhance the details of underwater image restoration. Then, we devised a dynamic information modulation module (DIMM), which adaptively modulated the output of the Mixed Transformer with appropriate weights based on input statistics to highlight important information. Further, a hybrid-attention fusion module (HAFM) adopted spatial and channel interaction to aggregate more delicate features, facilitating high-quality underwater image reconstruction. Extensive experiments on benchmark datasets revealed that our proposed DSMN surpasses the most renowned SR methods regarding quantitative and qualitative metrics, along with less computational effort.

由于水下环境的复杂性,如光的吸收、散射和色彩失真,图像超分辨率(SR)是一项艰巨的挑战。许多深度学习方法已经为sr提供了实质性的性能提升。然而,这些方法不仅计算成本高,而且在适应严重退化的图像统计时往往缺乏灵活性。为了解决这些问题,我们提出了一种动态结构感知调制网络(DSMN)来实现高效准确的水下图像复原。混合变压器由结构感知变压器块和多头变压器块组成,可以综合利用局部结构属性和全局特征来增强水下图像复原的细节。然后,我们设计了动态信息调制模块(DIMM),该模块根据输入统计量对混合变压器的输出进行适当的权重自适应调制,以突出重要的信息。此外,混合注意力融合模块(HAFM)采用空间和通道交互,聚合更精细的特征,实现高质量的水下图像重建。在基准数据集上进行的大量实验表明,我们提出的DSMN在定量和定性指标方面超过了最著名的SR方法,并且计算量更少。
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引用次数: 0
A Comprehensive Review of Treatment Plans for Marginal Enamel Fractures in Anterior Teeth. 前牙边缘牙釉质骨折治疗方案综述。
IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY Pub Date : 2024-12-18 DOI: 10.3390/biomimetics9120770
Riccardo Favero, Alessandro Scattolin, Martina Barone, Giampaolo Drago, Rim Bourgi, Vincenzo Tosco, Riccardo Monterubbianesi, Angelo Putignano

Marginal enamel fractures (MEF) are a common clinical concern in dentistry, particularly in anterior teeth. These fractures occur at the enamel margins and their etiopathogenesis involves a complex interplay of mechanical, chemical, and biological factors. The ongoing research focuses on an overview of MEF to improve the knowledge about this condition. Understanding the multifaceted nature of MEF is crucial for devising effective preventive and therapeutic strategies in contemporary restorative dentistry. Indeed, mechanical stresses, such as occlusal forces and parafunctional habits are primary contributors for MEF. Additionally, it can happen at the enamel-restoration interface due to expansion and contraction of restorative materials. Chemical degradation, including acid erosion and the breakdown of adhesive bonds, further exacerbates the vulnerability of enamel. Biological factors, such as enamel composition and the presence of micro-cracks also play a role in the development of MEF. Clinical management of MEF involves subtractive or additive techniques, repairing or replacing the compromised tooth structure using techniques to ensure the integration with the natural enamel.

牙釉质边缘骨折(MEF)是牙科常见的临床问题,特别是在前牙。这些骨折发生在牙釉质边缘,其发病机制涉及机械、化学和生物因素的复杂相互作用。正在进行的研究重点是对MEF的概述,以提高对这种情况的认识。了解MEF的多面性是制定有效的预防和治疗策略在当代牙科修复至关重要。事实上,机械应力,如咬合力和功能习惯是MEF的主要贡献者。此外,由于修复材料的膨胀和收缩,它可能发生在珐琅-修复界面。化学降解,包括酸侵蚀和粘合剂的破坏,进一步加剧了牙釉质的脆弱性。生物因素,如牙釉质成分和微裂纹的存在也对MEF的发展起作用。MEF的临床治疗包括减法或加法技术,使用技术修复或替换受损的牙齿结构,以确保与天然牙釉质的融合。
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引用次数: 0
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