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"Disorders of Energy Metabolism in Neurons of the Cerebral Cortex During Cerebral Ischemia" 脑缺血时大脑皮层神经元能量代谢紊乱
Pub Date : 2021-11-19 DOI: 10.26717/bjstr.2021.40.006402
Lizaveta I. Bon
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引用次数: 0
"Serum Calcium in Relation to COVID-19 in Asian Population: A Two-Sample Mendelian Randomization Study" 亚洲人群血清钙与COVID-19的关系:一项双样本孟德尔随机化研究
Pub Date : 2021-11-18 DOI: 10.26717/bjstr.2021.40.006398
Lili Wang
To explore the causal relationship between serum calcium concentration and the risk of COVID-19 in Asian population, this study apply the analysis method of two samples of Mendelian randomization to demonstrate. Methods: Through literature search, the summary statistic data of the whole gene association study (GWAS) related to serum calcium concentration was obtained, and this data was subjected to secondary data analysis. From the large-sample GWAS summary data, the genetic variation closely related to the serum calcium concentration was selected as an instrumental variable. Five models (Inverse variance weighted, MR Egger, Weighted median, Simple mode and Weighted mode) were used for analyzing and evaluating the causal relationship between serum calcium concentration and the risk of COVID-19 with OR value and 95% confidence interval. Results: A total of 8 SNPs were included as instrumental variables in this study. The results of gene pleiotropy test showed that there was no gene pleiotropy (P = 0.54). The IVW results showed that each increase in serum calcium concentration by one standard deviation would reduce the risk of COVID-19 (OR=0.01, 95%CI: 0.0001-0.73, P=0.03). Conclusion: Appropriate supplementation of serum calcium concentration can help prevent the onset of COVID-19.
为探讨亚洲人群血钙浓度与COVID-19风险之间的因果关系,本研究采用孟德尔随机化两样本分析方法进行论证。方法:通过文献检索,获得与血钙浓度相关的全基因关联研究(GWAS)汇总统计资料,并对该资料进行二次资料分析。从大样本GWAS汇总数据中,选择与血钙浓度密切相关的遗传变异作为工具变量。采用反方差加权、MR Egger、加权中位数、简单模型和加权模型5种模型,用OR值和95%置信区间分析评价血钙浓度与COVID-19风险的因果关系。结果:本研究共纳入8个snp作为工具变量。基因多效性试验结果显示无基因多效性(P = 0.54)。IVW结果显示,血钙浓度每增加一个标准差,COVID-19的风险就会降低(OR=0.01, 95%CI: 0.0001 ~ 0.73, P=0.03)。结论:适当补充血钙有助于预防COVID-19的发病。
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引用次数: 0
"The Relationship of Perceived Service Quality and Expectation on Customer Satisfaction and Loyalty" 感知服务质量与期望对顾客满意和忠诚的影响
Pub Date : 2021-11-18 DOI: 10.26717/bjstr.2021.40.006396
T. Nguyen
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引用次数: 0
"Moderna COVID-19 mRNA Vaccine and its Observed Cardiac Side Effects in Adolescent and Children" 《现代COVID-19 mRNA疫苗及其在青少年和儿童中观察到的心脏副作用》
Pub Date : 2021-11-16 DOI: 10.26717/bjstr.2021.40.006391
Sohail Rao
Sohail Rao1,2*, Caitlin White2 and Manish Singh3 1Executive Vice President, DHR Health, 5501 S. McColl Road, Edinburg, Texas 78539, and President & Chief Executive Officer, DHR Health Institute for Research & Development, USA 2DHR Health Institute for Research & Development, 5323 S. McColl Road, Edinburg, Texas, USA 3Chief Executive Officer, DHR Health, 5501 S. McColl Road, Edinburg, Texas 78539 and DHR Health Bariatric & Metabolic Institute, USA
Sohail ra1,2*, Caitlin White2和Manish sing3 1 DHR Health, 5501 S. McColl Road, Edinburg, Texas, 78539,执行副总裁;2DHR Health, 5323 S. McColl Road, Edinburg, Texas, 5323 S. McColl Road, DHR Health,首席执行官;3 DHR Health, 5501 S. McColl Road, Edinburg, Texas, 78539, DHR Health减肥与代谢研究所,USA
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引用次数: 2
"Investigating Reliable Recovery Biomarkers of Ischemic Stroke: An Evidence-Based Study" 缺血性卒中可靠恢复生物标志物的研究:一项基于证据的研究
Pub Date : 2021-11-16 DOI: 10.26717/bjstr.2021.40.006388
P. Tiwari
In 2020, WHO reported that stroke is the second leading cause of death worldwide. Stroke recovery is the complex process due to its heterogeneous nature. Identification of reliable recovery biomarkers assist to advance the practice, rehabilitation and recovery after stroke. Objective: This systematic review aimed to assess the biomarkers and predictors of recovery in ischemic stroke. Methods: Case-control studies reporting the biomarkers and predictors of recovery in ischemic stroke patients were identified through PubMed, Wiley online library, Rehab data and PEDro databases. Studies in English language published after the year 2000 were included. Studies on animal models and patients with other psychiatric or neurological condition (other than stroke) were excluded. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of studies. Relative levels of recovery biomarkers in post-ischemic stroke patients were compared with the levels found in control subjects. Random effect model was used to calculate the mean effect size of studies. This systematic review was registered with PROSPERO (CRD42020209833). The results of this systematic review are based on 29 studies that covered 2528 participants (case:926 patients, control:1602 participants). A total of 22 markers were reported in this review. The core biomarkers differentiated ischemic stroke’s recovery from controls with good performance: Motor evoked potential [standardized mean difference -2.14, P=0.03], laterality index [standardized mean difference -1.32, P=0.03] and stimulus intensity [standardized mean difference 1.63, P=0.18]. Conclusion: The motor evoked potential, laterality index and stimulus intensity were found as relevant biomarkers that predict motor recovery in ischemic stroke patients.
2020年,世卫组织报告说,中风是全世界第二大死亡原因。由于中风的异质性,中风恢复是一个复杂的过程。确定可靠的恢复生物标志物有助于推进卒中后的实践、康复和恢复。目的:本系统综述旨在评估缺血性脑卒中恢复的生物标志物和预测因素。方法:通过PubMed、Wiley在线图书馆、Rehab data和PEDro数据库对报告缺血性脑卒中患者康复的生物标志物和预测因素的病例对照研究进行鉴定。2000年以后发表的英文研究也包括在内。排除了动物模型和其他精神或神经疾病(中风除外)患者的研究。采用纽卡斯尔-渥太华量表(NOS)评估研究质量。将缺血性脑卒中后患者恢复生物标志物的相对水平与对照组进行比较。采用随机效应模型计算各研究的平均效应量。本系统评价已在PROSPERO注册(CRD42020209833)。本系统综述的结果基于29项研究,涵盖2528名参与者(病例:926名患者,对照组:1602名参与者)。本综述共报道了22个标志物。将缺血性卒中恢复与表现良好的对照组区分的核心生物指标为:运动诱发电位[标准化平均差-2.14,P=0.03]、侧性指数[标准化平均差-1.32,P=0.03]和刺激强度[标准化平均差1.63,P=0.18]。结论:运动诱发电位、偏侧指数和刺激强度是预测缺血性脑卒中患者运动恢复的相关生物指标。
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引用次数: 0
"Physical-Recreational Games to Increase the Participation of Children in the Recreational Activities of the Bengochea District" “体育娱乐游戏提高本戈契地区儿童对娱乐活动的参与度”
Pub Date : 2021-11-16 DOI: 10.26717/bjstr.2021.40.006390
Rosa de la Cruz Hernández Moya
Phys-ical-Recreational Games to Increase the Participation of Children in the Recreational Activities the Bengochea The present investigation deals with the use of recreational physical games aimed at increasing the participation of boys from 9 – 12 years old in district # 9 of the Bengochea district, Santa Clara municipality, to recreational physical activities; for this, we start with the current diagnosis of participation in activities, based on the interests, tastes and preferences the boys, since passive entertainment has become widespread due to the marked fondness for video games, the use of tablets, computers, smartphones, among others. In order to explore the researched topic, different scientific and technical methods were used that allowed to consult bibliographies of several authors, national and foreign, this allowed to make the selection and evaluation of the implementation of ten physical recreational games, where the boys recognized the benefits of to realize active games, besides the acceptance and impact of these games, before the passive activities that they realized in their free moments.
体育娱乐游戏增加儿童参与娱乐活动本戈切亚目前的调查涉及娱乐性体育游戏的使用情况,目的是增加圣克拉拉市本戈切亚区第9区9至12岁男孩参与娱乐体育活动的情况;为此,我们根据男孩的兴趣、品味和偏好,从目前对参与活动的诊断开始,因为由于对视频游戏、平板电脑、电脑、智能手机等的明显喜爱,被动娱乐已经变得普遍。为了探索研究课题,使用了不同的科学技术方法,可以查阅几位国内外作者的参考书目,从而可以对十种体育娱乐游戏的实施进行选择和评估,在这些游戏中,男孩们认识到实现主动游戏的好处,除了这些游戏的接受和影响,在他们在空闲时间实现的被动活动之前。
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引用次数: 0
"Can Probiotics Play an Important Role Against COVID-19?" “益生菌能在对抗COVID-19中发挥重要作用吗?”
Pub Date : 2021-11-16 DOI: 10.26717/bjstr.2021.40.006389
M. Nawaz
Muhammad Nawaz1#*, Ahmed Donia2#, Amina Mustafa3, Nadir Ullah1, Nadia Mukhtar1, Tahir Yaqub1 and Habib Bokhari2,4 1Institute of Microbiology, University of Veterinary and Animal Sciences, Lahore, Pakistan 2Department of Biosciences, Faculty of Science, COMSATS University Islamabad, Islamabad, Pakistan 3Department of Molecular Biology, Virtual University of Pakistan, Lahore, Pakistan 4Kohsar University Murree, Pakistan #These authors contributed equally to this work
Muhammad Nawaz1#*, Ahmed Donia2#, Amina Mustafa3, Nadir Ullah1, Nadia Mukhtar1, Tahir Yaqub1和Habib Bokhari2,4 1巴基斯坦拉合尔兽医和动物科学大学微生物研究所2巴基斯坦伊斯兰堡COMSATS大学理学院生物科学系3巴基斯坦拉合尔虚拟大学分子生物学系4巴基斯坦穆尔里kohsar大学#这些作者对这项工作做出了同样的贡献
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引用次数: 0
"Comparing the Workplace Organization Method 5s with the 7 Wastes (Muda) in Waste and Failure Management Tool, in the Health Care Quality Management" 《工作场所组织方法5s与卫生保健质量管理中废物和失效管理工具中的7种废物(Muda)的比较》
Pub Date : 2021-11-15 DOI: 10.26717/bjstr.2021.40.006387
Ahsan Ali Siddiqui
Comparing the Workplace Organization Method 5s with the 7 Wastes (Muda) in Waste and Failure Background and Objective: The main theme of this article is to discuss and compare the workplace organization method 5S with the 7 wastes (Muda) in waste and failure management tool, in the health care quality management. Methods: The Author of this article has chosen literature review methodology of 18 random research articles and quality management websites. By reviewing the literature, we have chosen 10 different points in 18 articles discussing or agreeing on where 5S and 7 Muda are beneficial. Most of the chosen articles discusses the quality management in the health sector and their benefits. Results: There is a table and SPSS diagram representing the literature review regarding 18 articles including quality management website. Table title is (18 journal articles discusses and agrees to the following 10 points). SPSS diagram clearly shows the number of times each article discusses the chosen 10 points. The 10 points includes the agreement of points beneficial for health sector by using 5S and 7 Muda methodology. Conclusion: To conclude the article, 18 of the articles including the quality management websites agrees on the use of 5S and 7 Muda methodology. Different organization around the globe are using 5S and 7 Muda methodology to get benefits for improvement of their health care system. The step-by-step process of 5S and 7 Muda methodology is smart way to start, monitor, finish and follow up the broken health system in several countries.
背景与目的:本文的主要主题是讨论和比较工作场所组织法5s与7种废物(Muda)在卫生保健质量管理中的浪费和失效管理工具。方法:本文采用随机选取18篇研究论文和质量管理网站的文献综述方法。通过回顾文献,我们从18篇文章中选择了10个不同的观点来讨论或同意5S和7 Muda在哪些方面是有益的。大多数选定的文章讨论了卫生部门的质量管理及其好处。结果:对包括质量管理网站在内的18篇文章的文献综述,有表格和SPSS图表。表标题为(18篇期刊文章讨论并同意以下10点)。SPSS图表清楚地显示了每篇文章讨论所选10点的次数。10点包括通过使用5S和7 Muda方法商定对卫生部门有益的点。结论:包括质量管理网站在内的18篇文章同意使用5S和7 Muda方法。世界各地的不同组织都在使用5S和7muda方法来改善他们的医疗保健系统。5S和7 Muda方法的逐步过程是启动、监测、结束和跟踪几个国家破碎的卫生系统的明智方法。
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引用次数: 4
"Diagnostic Approach in X-Linked Adrenoleukodystrophy in the Pediatric Patient. A Case Report" 儿科患者x连锁肾上腺脑白质营养不良的诊断方法。个案报告"
Pub Date : 2021-11-15 DOI: 10.26717/bjstr.2021.40.006383
Efrain de Jesús Medina Cruz
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引用次数: 0
"Successful Treatment of a Chronically Infected and Occluded Aorto-Bifemoral Dacron® Bypass with Bacteriophages" 《利用噬菌体成功治疗慢性感染和阻塞的主动脉-双双口涤纶®分流术》
Pub Date : 2021-11-15 DOI: 10.26717/bjstr.2021.40.006384
F. Wiese
Successful Treatment of a Chronically Infected and Occluded Aorto-Bifemoral Dacron ® Bypass with Bacteriophages. Biomed J Sci & Tech Res
用噬菌体成功治疗慢性感染和阻塞的主动脉-双双口涤纶®旁路生物医学科学与技术研究所
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引用次数: 0
期刊
Biomedical Journal of Scientific & Technical Research
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