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"Rapid and Practical Screening Method for the Detection of Colistin-Resistant Bacteria in Food" 食品中耐粘菌素细菌的快速实用筛选方法
Pub Date : 2021-11-15 DOI: 10.26717/bjstr.2021.40.006381
Yoshimasa Yamamoto
Rapid and Practical Screening Method for the Detection of Colistin-Resistant Bacteria in Food. Biomed J Sci & Res We developed a rapid and practical screening method for simultaneously detecting both Escherichia coli and bacteria harboring the mcr-1 colistin resistance gene using high-speed real-time polymerase chain reaction with specific TaqMan probes. The entire procedure, from sample processing to the final result, was performed within 1 h. The practical utility of this method was verified by analyzing 27 retail meat samples for the presence of colistin-resistant bacteria. The results indicated the potential of this method for the convenient and rapid screening of food items to detect contamination with mcr-1 –positive bacteria, which can be especially useful for on-site testing in developing countries.
食品中耐粘菌素细菌的快速实用筛选方法研究。我们开发了一种快速实用的筛选方法,利用高速实时聚合酶链反应与特异性TaqMan探针同时检测大肠杆菌和携带mcr-1粘菌素耐药基因的细菌。从样品处理到最终结果的整个过程在1小时内完成。通过分析27份零售肉类样品中是否存在耐粘菌素细菌,验证了该方法的实用性。结果表明,该方法具有简便、快速筛选食品以检测mcr-1阳性细菌污染的潜力,可特别用于发展中国家的现场检测。
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引用次数: 0
"Health Risks of Simulium (Boophthora) erythrocephalum (De Geer, 1776) in the Valencian Autonomous Region, Eastern Spain" 西班牙东部巴伦西亚自治区红脑疫病菌(疫霉)的健康风险
Pub Date : 2021-11-12 DOI: 10.26717/bjstr.2021.39.006376
D. López-Peña
The presence and distribution of Simulium erythrocephalum 1776) in the Valencian Autonomous Region is analyzed, an arthropod of medical-sanitary importance due to the marked anthropophilic characteristics exhibited and the tendency to carry out massive attacks. The increasing incidence registered in certain areas as a consequence of their hematophagy, and the meager availability of epidemiological, fauna, bioecological, and distribution data, have led to this study. A field study of 137 samplings was carried out from 2013 to the present in the 14 hydrographic basins of the Valencian Autonomous Region. The study variables were the presence or absence of preimaginal states, environmental and physical-chemical parameters of the water, bite data from the Generalitat Valenciana, population density and incidence of bites by municipality, and geographic location of the population areas. A scarce and reduced presence of the aforementioned species is revealed in the study area. Risk maps of human populations near the detected breeding areas are provided, and the epidemiological interest is discussed due to its vector capacity to transmit pathogens that cause disease. The number of bites registered between 2015, 2016, 2017, and 2018 in the seven health departments involved is provided. The general trend toward an increase in the number of cases is observed year after year, where the highest peaks in the number of cases coincide with the months of June, July, and August, and eventually, September and October. Surveillance and control programs to minimize the problem in the Spanish health system are needed.
本文分析了巴伦西亚自治区赤头象(Simulium erythrocephalum 1776)的存在和分布,这是一种具有医学卫生重要性的节肢动物,因其表现出明显的亲人类特征和大规模攻击的倾向。在某些地区,由于它们的噬血行为,发病率不断上升,而流行病学、动物群、生物生态学和分布数据的可用性不足,导致了这项研究。从2013年到现在,在巴伦西亚自治区的14个水文盆地进行了137个样本的实地研究。研究变量为存在或不存在预想象状态、水的环境和物理化学参数、巴伦西亚省的咬伤数据、各市的人口密度和咬伤发生率以及人口区域的地理位置。上述物种在研究区内数量稀少且数量减少。提供了检测到的繁殖区附近人群的风险图,并讨论了流行病学的兴趣,因为它的媒介能力传播导致疾病的病原体。提供了2015年、2016年、2017年和2018年在七个相关卫生部门登记的咬伤数量。年复一年观察到病例数增加的总趋势,其中病例数的最高峰出现在6月、7月和8月,最终出现在9月和10月。监测和控制计划,以尽量减少西班牙卫生系统的问题是必要的。
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引用次数: 1
"Acetabulum Fractures: Mechanism of Injury, Demographic Features and Associated Injuries" 髋臼骨折:损伤机制、人口统计学特征及相关损伤
Pub Date : 2021-11-12 DOI: 10.26717/bjstr.2021.39.006379
Israr Ahmad
Muhammad Arif. Acetabulum Fractures: Mechanism of Injury, Demographic Features and Associated Injuries. Biomed Objectives: The study about the demographic characteristics of patients about common associated injuries and various Study Design:
Arif默罕默德。髋臼骨折:损伤机制、人口统计学特征和相关损伤。目的:研究常见相关损伤患者的人口学特征和各种研究设计:
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引用次数: 0
"Remote Monitoring of the Health Status of Pregnant Women at Risk for Preeclampsia" 《子痫前期孕妇健康状况的远程监测》
Pub Date : 2021-11-12 DOI: 10.26717/bjstr.2021.39.006378
N. Ankudinov
Remote itoring of the Health Status of Pregnant Women at Risk for Preeclampsia. The article presents the practical application of telemedicine information technologies that have allowed maternity institutions of the Sverdlovsk region to carry out remote monitoring the health of patients during pregnancy with hypertension and at risk for preeclampsia.
子痫前期危险孕妇健康状况的远程监测本文介绍了远程医疗信息技术的实际应用,该技术使斯维尔德洛夫斯克地区的产科机构能够对怀孕期间患有高血压和有子痫前期风险的患者的健康状况进行远程监测。
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引用次数: 0
"Remote Monitoring of the Health Status of Pregnant Women in the COVID-19 Pandemic" “COVID-19大流行期间孕妇健康状况的远程监测”
Pub Date : 2021-11-12 DOI: 10.26717/bjstr.2021.40.006380
N. Ankudinov
Remote of the Health Status Women COVID-19 The article presents the practical application of telemedicine information technologies that have allowed maternity institutions of the Sverdlovsk region to carry out remote monitoring the health of pregnant women and maternity hospitals, including during outpatient treatment (at home) with asymptomatic and mild COVID-19.
本文介绍了远程医疗信息技术的实际应用,该技术使斯维尔德洛夫斯克地区的妇产机构能够对孕妇和妇产医院的健康状况进行远程监测,包括在无症状和轻度COVID-19患者的门诊(在家)治疗期间。
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引用次数: 0
"Level of Activity Limitation Due to Joints Pain among Hemophilia Patients" 血友病患者关节疼痛导致的活动受限程度
Pub Date : 2021-11-12 DOI: 10.26717/bjstr.2021.39.006377
Saeed Taj Din
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引用次数: 0
Autism Prevalence in New Jersey Correlates with Low Sulfate in Tap Water 新泽西州自闭症患病率与自来水中低硫酸盐有关
Pub Date : 2021-11-11 DOI: 10.26717/bjstr.2021.39.006372
Williams Richard J
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引用次数: 0
"Evaluation of the Effect of a Mobile Phone Application on Treatment Success and Drug Adherence in Hypertensive Patients" 《手机应用对高血压患者治疗成功及药物依从性的影响评价》
Pub Date : 2021-11-11 DOI: 10.26717/bjstr.2021.39.006373
Mert Kaşkal
Evaluation of the Effect of a Mo bile Phone Application on Treatment Suc cess and Drug Adherence in Hypertensive Patients. One of the most important factors affecting the prognosis of hypertension is the patients’ adherence to drug therapy. In this study, it was aimed to evaluate the improvement in drug adherence in hypertensive patients after using a mobile phone application. Patients and Methods: In this single-centered study fifty patients with hypertension were recruited. All the patients used the Medisafe® mobile phone application for 8 weeks. The application is intended to increase drug adherence of patients and provide better blood pressure control. The differences in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels from the baseline and the levels at the end of the study were compared. The drug adherence was evaluated using the 8-question Morisky Drug Adherence Scale (MMAS-8) at baseline and at the end of the study. Results: The mobile application utilization provided a significant decrease in both the mean SBP levels by 6.2 mmHg (p<0,001) and in the mean DBP levels by 2.4 mmHg (p=0.035) Additionally, the mobile application also positively and significantly increased the drug adherence of the patients (mean baseline score: 5.54 vs mean end of the study score:6.3 and p=0,001). In the subgroup analysis of the study demonstrated that in addition to an increase in patients drug adherence, the use of the mobile application provided a significant decrease in the mean SBP levels by 6.6 mmHg(p=0.016) in geriatric patients but the decrease in DBP did not significantly change (p>0.05). In geriatric patients, the mean difference between drug adherence scores baseline and after application was found to be significant (p=0.006). With the use of mobile application, patients with polypharmacy had decreased mean SBP and DBP levels, and an increased mean MMAS-8 score of 5.07 to 5.85 (p=0.009). The present pilot study demonstrated that mobile application use in patients with hypertension may increase the treatment success and the patients drug adherence. The beneficial effects of mobile applications in the treatment of hypertension and other common chronic diseases should be evaluated in further larger clinical trials.
手机应用对高血压患者治疗成功率及药物依从性的影响评价。影响高血压预后的重要因素之一是患者对药物治疗的依从性。本研究旨在评估使用手机应用程序后高血压患者药物依从性的改善情况。患者和方法:在这项单中心研究中,招募了50例高血压患者。所有患者使用Medisafe®手机应用程序8周。该应用程序旨在增加患者的药物依从性,并提供更好的血压控制。比较基线和研究结束时收缩压(SBP)和舒张压(DBP)水平的差异。在基线和研究结束时使用8题莫里斯基药物依从性量表(MMAS-8)评估药物依从性。结果:移动应用程序的使用使两组患者的平均收缩压水平显著降低6.2 mmHg (p0.05)。在老年患者中,药物依从性评分基线和用药后的平均差异有统计学意义(p=0.006)。使用移动应用程序后,多药患者的平均收缩压和舒张压水平下降,平均MMAS-8评分升高,为5.07 ~ 5.85 (p=0.009)。目前的初步研究表明,在高血压患者中使用移动应用程序可以提高治疗成功率和患者的药物依从性。移动应用程序在治疗高血压和其他常见慢性病方面的有益效果应在更大规模的临床试验中进行评估。
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引用次数: 0
"Little Adjustment of Lowry and Biuret Methods to Get Better Absorbance of Proteins" “对劳瑞法和双缩脲法进行小调整以获得更好的蛋白质吸光度”
Pub Date : 2021-11-10 DOI: 10.26717/bjstr.2021.39.006367
Yohannis Wondwosen
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引用次数: 0
"Novel Ideas for the Treatment of No- Option Critical Limb Ischemia" “无选择危急肢体缺血治疗的新思路”
Pub Date : 2021-11-10 DOI: 10.26717/bjstr.2021.39.006369
N. Angelides
Critical limb ischemia (CLI) is the advanced stage of peripheral arterial occlusive disease (PAOD). This stage can be considered as a step prior to impending gangrene and amputation. Recently, it has been demonstrated that the use of stem cells and gene therapy, either alone or in combination in cases of no-option CLI, can provide therapeutic benefits in terms of relieving the rest-pain and healing the ischaemic ulcers. It seems, that although such combinations of treatment are safe, a grey area still exists to whether they are effective in reducing the risk of amputation and improving the quality of life to a reasonable degree. More studies are necessary.
临界肢体缺血(CLI)是外周动脉闭塞性疾病(PAOD)的晚期。这个阶段可以被认为是即将发生坏疽和截肢之前的一个步骤。最近,研究表明,在无选择的CLI病例中,干细胞和基因治疗的单独或联合使用,可以在缓解静息痛和愈合缺血性溃疡方面提供治疗益处。虽然这些治疗组合是安全的,但它们是否能有效地降低截肢的风险,并在一定程度上提高生活质量,似乎仍然存在一个灰色地带。更多的研究是必要的。
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Biomedical Journal of Scientific & Technical Research
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