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PCOS and uveitis: a case report 多囊卵巢综合征合并葡萄膜炎1例
Pub Date : 2018-06-13 DOI: 10.15406/aovs.2018.08.00298
Ryan Capouch, Caryn LaBuda
Uveitis is a condition of inflammation of the uveal tract of the eye. This inflammation can be located in the iris, ciliary body, or the choroid or any combination of the three. This inflammation can be considered idiopathic in approximately 50% of individuals if the uveitis is only affecting the iris or the ciliary body. (Kanski). Typically in a patient who has an anterior uveitis episode, the initial episode is considered idiopathic until proven otherwise. However if the patient gets another bout of anterior uveitis then the provider begins to question whether there is some type of underlying immunological component. (Kanski) Polycystic ovary syndrome (PCOS) is a disease characterized by hyperandrogenism, absent or sparse ovulation, and multiple cysts on or around the ovaries.1 It affects 4-10% of reproductive-aged women, making it one of the most common female endocrinopathies.1 Up to 70% of women diagnosed with PCOS also experience insulin resistance, which is argued to be either a contributing cause to or a resultant effect of the disease.1 Many in the scientific community have contested that PCOS is a disease of inflammation, characterized by increases in pro-inflammatory markers.1–5
葡萄膜炎是眼部葡萄膜道发炎的一种情况。这种炎症可以发生在虹膜、睫状体、脉络膜或三者的任何组合。如果葡萄膜炎仅影响虹膜或睫状体,则约50%的人可认为这种炎症是特发性的。(Kanski)。通常,在有前葡萄膜炎发作的患者中,最初的发作被认为是特发性的,除非有其他证据。然而,如果病人再次出现前葡萄膜炎,医生就会开始怀疑是否有某种潜在的免疫成分。(Kanski)多囊卵巢综合征(PCOS)是一种以雄激素分泌过多、排卵缺失或稀疏、卵巢上或周围多发囊肿为特征的疾病它影响4-10%的育龄妇女,使其成为最常见的女性内分泌疾病之一多达70%被诊断为多囊卵巢综合征的女性也会经历胰岛素抵抗,这被认为是导致多囊卵巢综合征的原因或结果科学界的许多人都认为多囊卵巢综合征是一种炎症疾病,其特征是促炎标志物的增加
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引用次数: 1
New frontiers of drug delivery innovation in cataract surgery 白内障手术给药创新的新领域
Pub Date : 2018-06-12 DOI: 10.15406/AOVS.2018.08.00297
S. Pandey, Vidushi Sharma
drainage which cause the drug to be systemically absorbed across the nasal mucosa or the gastrointestinal tract. A significant systemic loss from topically applied drugs also occurs from conjunctival absorption into the local circulation. Tear turnover, which can also be stimulated by factors such as pH and tonicity of the formulation, remove drug solution from the conjunctival cul-de-sac in a few minutes.
使药物通过鼻黏膜或胃肠道被全身吸收的引流。局部应用药物的显著系统性损失也发生在结膜吸收进入局部循环。泪液周转也可能受到pH值和配方的滋补性等因素的刺激,在几分钟内将药物溶液从结膜死囊中清除。
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引用次数: 1
Meibomian gland dysfunction: an overlooked eyelid disease 睑板腺功能障碍:一种被忽视的眼睑疾病
Pub Date : 2018-05-29 DOI: 10.15406/aovs.2018.08.00295
B. Turgut, O. Çatak, T. Demir
The term ‘‘Meibomian gland disease” is used to describe various disorders of MGs such as congenital lack, neoplastic and inflammatory disorders, replacement distichiasis and MGD. The term has been first coined in the ophthalmic literature by Korb and Henriques in 1980s and it has been defined as a chronic MGD resulting in decreased secretion or poor quality of meibum. Lastly, MGD has been defined by subcommittee of The International Workshop on MGD (IWMGD) in 2011 as ‘’a chronic, diffuse abnormality of the MGs, commonly characterized by terminal duct obstruction and/or qualitative/ quantitative changes in the glandular secretion which may result in alteration of the tear film, clinical apparent inflammation, OSD and symptoms of eye irritation’’.2–4
“睑板腺疾病”一词用于描述先天性睑板腺缺乏、肿瘤和炎症性疾病、代偿性睑板腺病和睑板腺病等各种睑板腺疾病。该术语最早由Korb和Henriques于20世纪80年代在眼科文献中提出,并被定义为导致分泌减少或代谢质量差的慢性MGD。最后,2011年MGD国际研讨会(IWMGD)小组委员会将MGD定义为“MGD的慢性弥漫性异常,通常以终末导管阻塞和/或腺体分泌的定性/定量变化为特征,可能导致泪膜改变、临床明显炎症、OSD和眼睛刺激症状”
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引用次数: 5
Semiescleral lens adaptation in patient of 10 years after cornea transplantation 角膜移植术后10年患者的半巩膜晶状体适应
Pub Date : 2018-05-21 DOI: 10.15406/AOVS.2018.08.00293
N. Planas, Enrique Jiménez Gañán, S. Herrero
A 10-year-old patient who presented with a decrease in visual acuity (VA) and left eye (IT) itching of one day of evolution, with no personal history of interest. It does not report trauma or previous personal history of ocular infection. Interrogating the patient reports rubbing in both eyes for a long time. Under slit lamp mixed hyperemia and a large zone of central corneal edema of 5 x 5.5 mm are observed. It looks like a Descemet break located in the central zone. Tyndall or Seidel is not observed, and the anterior chamber appears preserved. The visual acuity that it presents in that eye is from fingers to 20 centimeters (in the right eye, healthy, it is from the unit) (Figure 1).
一名10岁患者,表现为视力下降(VA)和左眼(IT)瘙痒,持续一天,无个人病史。它没有外伤或既往眼部感染的个人病史。询问病人时报告说,他双眼揉搓了很长时间。裂隙灯下观察到混合性充血和5 × 5.5 mm的大面积角膜中央水肿。看起来像是在中心区域有一个断层。未观察到廷德尔或赛德尔,前房似乎保存完好。这只眼睛的视力从手指到20厘米(在健康的右眼,它来自这个装置)(图1)。
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引用次数: 0
Ocular syphilis: a rare manifestation in a low risk population 眼梅毒:低危人群中一种罕见的表现
Pub Date : 2018-05-21 DOI: 10.15406/AOVS.2018.08.00294
C. George, N. Christenson, Wade Rankin
Syphilis has been called “The Great Masquerader” due to its propensity to affect any organ system and produce a diverse array of signs and symptoms. Ocular syphilis is just one possible expression of this disease. The over whelming majority of patients with syphilis present with a sign or symptom preceding, or in concurrence with, ocular manifestations. These individuals also usually fall into one or more high-risk categories. However, as this case highlights, manifestations can occur solely in the eye and in lower risk populations. DOI: 10.29011/JFOA-106. 100006
梅毒被称为“伟大的假面舞会者”,因为它倾向于影响任何器官系统,并产生各种各样的体征和症状。眼梅毒只是这种疾病的一种可能表现。绝大多数梅毒患者在眼部表现之前或同时出现体征或症状。这些人通常也属于一个或多个高风险类别。然而,正如本病例所强调的那样,表现可能仅发生在眼睛和低风险人群中。DOI: 10.29011 / jfoa - 106。100006
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引用次数: 0
Non-central diabetic clinical significant macular edema treatment with 532nm sub threshold laser 532nm亚阈值激光治疗非中枢性糖尿病临床显著黄斑水肿
Pub Date : 2018-05-17 DOI: 10.15406/aovs.2018.08.00291
A. Marashi
Purpose: is to determine if Sub Threshold Laser at 532 nm can reduce macular thickness in non-central Clinical Significant Macular Edema (CSME) and stop the progression of non-central CSME to central CSME. Methods: 8 eyes in 6 patients were diagnosed with non-central CSME using OCT and were treated with Sub Threshold Laser at 532 nm using 5 % duty cycle using high density low intensity application on the area of the edema, retreatment was allowed with Sub Threshold Laser whenever macular edema worsening. Main outcome and measures: A complete fundus exam including best-corrected visual acuity changes within 24 weeks, improvement of non-central retinal thickness and monitoring glycemic control. Results: Reduction of retinal thickness from 384.5±64.5µm to 311.33±51.7µm at 24 weeks follow up (P<0.05) without changes of best corrected visual acuity along with reduced risk of progression to central CSME and visual loss with no sign of laser burns at the macular area. Conclusion: 532nm subthreshold laser is effective in NON-central CSME treatment for 24 weeks follow up and reduce the risk of visual loss due development of central CSME without causing retinal scars.
目的:确定532 nm亚阈值激光是否能减少非中枢性临床显著性黄斑水肿(CSME)患者的黄斑厚度,并阻止非中枢性CSME向中枢性CSME的进展。方法:对6例8眼OCT诊断为非中枢性CSME的患者行532 nm、5%占空比的亚阈值激光治疗,当黄斑水肿加重时,可再次行亚阈值激光治疗。主要结果和措施:完成眼底检查,包括24周内最佳矫正视力变化,非中央视网膜厚度改善和血糖控制监测。结果:随访24周时,视网膜厚度由384.5±64.5µm降至311.33±51.7µm (P<0.05),最佳矫正视力无变化,进展为中枢性CSME的风险降低,视力丧失,黄斑区无激光灼伤迹象。结论:532nm阈下激光治疗非中枢性CSME随访24周有效,可降低中枢性CSME发展导致视力丧失的风险,且无视网膜瘢痕。
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引用次数: 2
The role of vision in the science and art of the putting stroke in the sport of golf 视觉在高尔夫运动中推杆击球的科学和艺术中的作用
Pub Date : 2018-05-17 DOI: 10.15406/aovs.2018.08.00292
B. DeBroff
Golf is a popular sport that requires coordination, eye-hand coordination, and complex sensory motor skills to judge distance, speed, and conditions such as slope, grass height, and subtle angles and curvatures that can impact ball flight, trajectory, and roll. Experience, acquired skill, and psychological aspects can impact performance. According to the PGA, approximately 40% of all strokes in a given golf round involve putting the ball on the golf green. The art and skill of putting requires complex sensorimotor input for successful execution. This article reviews the contribution of scientific research in vision and its impact on successful putting in the sport of golf. Putting performance is dependent upon determining the proper putter speed required to displace the ball from its resting position to the hole taking into consideration the friction between the ball and grass, the vertical displacement of the hole relative to the ball, the distance the ball must travel to reach the hole, and the direction and magnitude of the break of the green. Vision and proper visual processing by the brain are vital components to successful execution of this complex skill. Electroencephalography studies have demonstrated that expert golfers demonstrate greater stimulation of regions of their brains as compared with novice counterparts, indicating greater sensory information processing.1
高尔夫是一项受欢迎的运动,需要协调、手眼协调和复杂的感觉运动技能来判断距离、速度和条件,如斜坡、草高、微妙的角度和曲率,这些都会影响球的飞行、轨迹和滚动。经验、获得的技能和心理方面都会影响表现。根据美国职业高尔夫协会(PGA)的数据,在一个特定的高尔夫回合中,大约40%的击球都是将球放在果岭上。推杆的艺术和技巧需要复杂的感觉运动输入才能成功执行。本文综述了视觉科学研究的贡献及其对高尔夫运动中成功推杆的影响。推杆的性能取决于确定将球从静止位置推到球洞所需的适当推杆速度,同时考虑到球与草地之间的摩擦、球洞相对于球的垂直位移、球到达球洞必须行进的距离以及果岭断裂的方向和大小。视觉和大脑适当的视觉处理是成功执行这一复杂技能的重要组成部分。脑电图研究表明,与新手相比,高尔夫高手的大脑区域受到的刺激更大,这表明他们的感觉信息处理能力更强
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引用次数: 2
Ocular masquerade syndrome 眼部假面具综合征
Pub Date : 2018-05-14 DOI: 10.15406/AOVS.2018.08.00290
B. Turgut
conjunctival carcinoma presenting as chronic conjunctivitis, an extraocular inflammatory disorder.1 However, especially a group of malignant and non-malignant systemic or primary ocular diseases mimicking immune-mediated uveitis have been also included into the spectrum of this syndrome. Ocular Masquerade Syndrome (OMS) is often misdiagnosed as chronic uveitis, in the other words, OMS is a group disease of the causes of pseudo-uveitis. However, in OMS, cells arise from a non-inflammatory origin (intraocular pigment, blood, or neoplastic cells). The most common features of this entity are bilateral asymmetrical involvement, the presence of aqueous and/ or vitreous cells, older age, history of systemic or ocular malignancy, the absence of other inflammatory signs such as ocular pain, keratic precipitates and synechiae, and initial response and eventual resistance to corticosteroids.2–4 OMS usually points out malignant entities including sebaceous gland carcinoma (meibomian gland carcinoma or sebaceous adenocarcinoma), intraocular and periocular lymphoma, retinoblastoma, diffuse amelanotic ocular melanoma and metastatic tumors to the choroid and retina. The incidence of malignant entities in OMS is 2-8% of cases in a uveitis practice.2–4
结膜癌表现为慢性结膜炎,一种眼外炎性疾病然而,特别是一组恶性和非恶性系统性或原发性眼部疾病,类似免疫介导的葡萄膜炎,也被纳入该综合征的频谱。眼部假面具综合征(Ocular Masquerade Syndrome, OMS)常被误诊为慢性葡萄膜炎,是引起假性葡萄膜炎的一组疾病。然而,在OMS中,细胞起源于非炎症来源(眼内色素、血液或肿瘤细胞)。该疾病最常见的特征是双侧不对称受累,存在水样和/或玻璃体细胞,年龄较大,系统性或眼部恶性肿瘤史,无其他炎症征象,如眼痛、角状沉淀和粘连,对皮质类固醇的初始反应和最终抵抗。2-4 OMS通常指出的恶性实体包括皮脂腺癌(睑板腺癌或皮脂腺癌)、眼内和眼周淋巴瘤、视网膜母细胞瘤、弥漫性无色素眼部黑色素瘤和向脉络膜和视网膜转移的肿瘤。恶性实体在OMS中的发病率是葡萄膜炎病例的2-8%
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引用次数: 3
A providential ptosis revealing a tumor of the cavum 天意上睑下垂,显露出腔内肿瘤
Pub Date : 2018-05-02 DOI: 10.15406/aovs.2018.08.00289
Youssoufou Souley Abdoul Salam, L. Nisrine, A. Alwan, El Ouattassi Narjis, R. Karim, O. Abdelbarre
Nasopharyngeal cancer is an endemic tumor of the Mediterranean rim. The usual clinical symptoms are dominated by cervical lymphadenopathy, otological and rhinological signs. Ophthalmological involvement is rarely indicative of the tumor and is seen especially at the late stage of the disease. The treatment of choice is radiotherapy associated with concomitant chemotherapy in certain evolved forms. We report a case of cavum cancer that was revealed by ptosis.
鼻咽癌是地中海沿岸的一种地方性肿瘤。常见临床症状以颈淋巴肿大、耳鼻喉征为主。眼科受累很少是肿瘤的指示,尤其是在疾病的晚期。治疗的选择是放射治疗与某些进化形式的伴随化疗。我们报告一个因上睑下垂而发现的腔癌病例。
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引用次数: 0
Study of familial pattern in patients with hyperopia 远视患者家族性模式的研究
Pub Date : 2018-04-26 DOI: 10.15406/AOVS.2018.08.00286
I. Iqbal, Javaria Asif Bajwa
Purpose: Purpose of the study was: To determine the most prevalent type of hyperopia. To determine the familial pattern in patients with hyperopia, including hereditary and genetic model. Methodology: A cross sectional convenient type study was conducted at Eye Department, Mayo hospital, Lahore Pakistan. It included selection of research type, target population, sample size, study design of survey, Perform and dummy tables, sampling method, research methodology, organizational issues, pilots study and work plan. The study was committed in the months of August, September and October 2013. All the sample size was screened for hyperopia. Performa and questionnaire was formed from data collection. Results: Out of total 100 hyperopic patients, 53(53%) were female while 47(47%) were male. 41(41%) were with the complaint of decreased vision, 13(13%) were with blurring, 1(1%) was with watering, 3% with itching, 6% with headache and 35% were with all these combined symptoms. All these patients were usingspectacles and none were using contact lenses. 82(82%) of these patients were using spectacles for the last 1 year, 16(16%) for the last 1-3 years and 2(2%) were using spectacles for the last 4-6 years. Out of total 100 hyperopic patients 89(89%) were having no ocular history, 10(10%) were having previous ocular history, while 1(1%) were unaware of their ocular history. 70(70%) out of 100 were having no family history of hyperopia, 2(2%) have father with hyperopia history, 9(9%) have history of hyperopia in mother, 11(11%) in their brothers and 8(8%) were having history of hyperopia in their sisters. Conclusion: This study showed that no strong family history is associated with hyperopia. Only 11% of patients had hyperopia in both parents, all exhibiting with the hyperopia and almost clear fundus shows small positive correlation between maternal hyperopia and hyperopia in their children indicating heritable hyperopia susceptibility.
目的:本研究的目的是:确定最常见的远视类型。目的:确定远视患者的家族性模式,包括遗传模式和遗传模式。方法:在巴基斯坦拉合尔梅奥医院眼科进行了一项横断面便捷型研究。包括研究类型的选择、目标人群、样本量、调查的研究设计、Perform和dummy tables、抽样方法、研究方法、组织问题、试点研究和工作计划。该研究于2013年8月、9月和10月进行。所有的样本量都进行了远视筛查。通过数据收集形成绩效表和问卷。结果:100例远视患者中,女性53例(53%),男性47例(47%)。有视力下降41例(41%),视力模糊13例(13%),流泪1例(1%),瘙痒3%,头痛6%,合并上述症状35%。所有这些患者都戴眼镜,没有人戴隐形眼镜。这些患者中有82例(82%)在过去1年使用眼镜,16例(16%)在过去1-3年使用眼镜,2例(2%)在过去4-6年使用眼镜。在100例远视患者中,89例(89%)无眼部病史,10例(10%)既往有眼部病史,1例(1%)不知道自己的眼部病史。100人中无远视家族史70例(70%),父亲有远视史2例(2%),母亲有远视史9例(9%),兄弟有远视史11例(11%),姐妹有远视史8例(8%)。结论:本研究显示远视无明显的家族史。只有11%的患者父母双方均有远视,均表现为远视,眼底几乎清晰,母体远视与子女远视有小的正相关,提示遗传性远视易感性。
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引用次数: 0
期刊
Advances in ophthalmology & visual system
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