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Fungal hyphae in the Anterior Chamber in a case of Anterior Uveitis: A case report 葡萄膜前炎前房真菌菌丝1例报告
Pub Date : 2018-07-27 DOI: 10.15406/AOVS.2018.08.00309
Saurabh Deshmukh, Dipankar Das, Jnanankar Medhi, H. Bhattacharjee, Krati Gupta, Priya T. Bhola
Uveitis is the inflammation of the vascular coat of the eyeball and it can either be anterior, intermediate, posterior or panuveitis depending on the structures involved. Anterior uveitis is the commonest form.1 Ocular fungal infections most commonly involve the cornea, anterior chamber, and the vitreous.2 One important fungus is the Fusarium. It is a filamentous fungus, is ubiquitous and commonly found in the soil and on the plants. It is a common cause of fungal keratitis and keratitisassociated fungal endophthalmitis.3 F. solani and F. oxysporum are the most common species affecting the humans, with F. solani being the most virulent. Numerous cases of keratitis and endophthalmitis caused by F. solani and F. oxysporum have been reported but a case of isolated anterior uveitis has not been reported in the literature.4 Herein, this case report emphasizes on considering the morphological characteristics of the lesion when making a provisional diagnosis. To the best of our knowledge, this is the first case report describing the fungal hyphae in the anterior chamber as a cause of anterior uveitis.
葡萄膜炎是眼球血管层的炎症,它可以是前、中、后或全葡萄膜炎,这取决于所涉及的结构。前葡萄膜炎是最常见的一种眼部真菌感染最常累及角膜、前房和玻璃体一种重要的真菌是镰刀菌。它是一种丝状真菌,普遍存在于土壤和植物中。它是真菌性角膜炎和与角膜炎相关的真菌性眼内炎的常见原因梭兰弧菌和尖孢弧菌是影响人类最常见的菌种,其中梭兰弧菌毒性最强。由梭兰梭菌和尖孢梭菌引起的角膜炎和眼内炎的病例已经报道了很多,但文献中尚未报道一例孤立的前葡萄膜炎在此,本病例报告强调在进行临时诊断时考虑病变的形态学特征。据我们所知,这是第一个描述前房真菌菌丝作为前葡萄膜炎原因的病例报告。
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引用次数: 2
Neglected left periocular neuroendocrine tumor with a debatable origin: histopathological case report and brief review of the literaturereport and brief review of the literature 被忽视的左侧眼周神经内分泌肿瘤,起源有争议:组织病理病例报告及文献综述
Pub Date : 2018-07-20 DOI: 10.15406/AOVS.2018.08.00308
F. Alqahtani, H. Alkatan, S. Husain, Hattan Alkhiary
The most common location of small cell neuro endocrine tumor (NET)is pulmonary, while the overall incidence of extra pulmonary NET is less observed. The extra pulmonary sites include the salivary glands, sinuses, thyroid, larynx, trachea, pleura, thymus, gastrointestinal tract, genitourinary tract, ovary, uterus, cervix, brain, lymph nodes, skin and eyelids.1 Non-ocular NET has been reported in various anatomic locations; however, primary orbital NET is uncommon, and majority of cases are metastatic.2 The orbit has been reported to be involved by NET in only 4-5% of all orbital metastatic cases.3 NET of the eyelid is a rare entity that has not been reported extensively in the ophthalmic literature.4 In this case report we describe a case of an aggressive neglected NET involving the left eyelids and anterior orbit. The case, was diagnosed based on histopathological features and immuno histochemical staining, however the origin of the tumor remained debatable.
小细胞神经内分泌肿瘤(NET)最常见的位置是肺,而肺外NET的总体发生率较低。额外的肺部位包括唾液腺、鼻窦、甲状腺、喉部、气管、胸膜、胸腺、胃肠道、泌尿生殖道、卵巢、子宫、子宫颈、大脑、淋巴结、皮肤和眼睑在不同的解剖部位都有非眼部NET的报道;然而,原发性眼眶NET并不常见,多数为转移性据报道,在所有眼眶转移病例中,只有4-5%的病例发生NET累及眼眶眼睑的NET是一种罕见的实体,在眼科文献中尚未广泛报道在这个病例报告中,我们描述了一个侵袭性被忽视的NET涉及左眼睑和前眼眶的病例。该病例是根据组织病理学特征和免疫组织化学染色诊断的,但肿瘤的起源仍有争议。
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引用次数: 0
Physician heal thyself: tips to manage stress & burnouts among doctors in India 医生治疗自己:印度医生管理压力和倦怠的技巧
Pub Date : 2018-07-20 DOI: 10.15406/aovs.2018.08.00307
P. SureshK, Ey, Vidushi Sharma
The situation is even worse in India. According to a report, 19.5% females and 12% males in the health care experience depression, this is even more prevalent among medical students as around 15 to 30% medical students screened positive for depression. Another study conducted by Indian Journal of Critical Care Medicine showed that 14% of health care professionals are heavy smokers, 18% depend on antidepressants, and 21% drink alcohol in high volumes.3
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引用次数: 3
Florid retinopathy: a rapidly progressive form of proliferative diabetic retinopathy 黄斑视网膜病变:一种快速进展的增生性糖尿病视网膜病变
Pub Date : 2018-07-19 DOI: 10.15406/aovs.2018.08.00306
B. Turgut
The complications of FDR are VH, tractional RD, neovascular glaucoma, and blindness in a very short time such as a few weeks or months. Thus, to prevent the destructive consequences of FDR, the management of the disease includes early diagnosis and aggressive treatment with an extensive pan-retinal photocoagulation (PRPC) and when necessary, early pars plana vitrectomy (PPV).1,2,6-8 Intravitreal anti-VEGF drug and steroid injections should be considered as the adjunctive treatment to obtain NV regression and interventional easiness for PRFC and PPV, if markedly fibrovascular vitreoretinal traction is not observed.9-11 Recent reports on the treatment of FDR showed that pituitary ablation, insulin-infusion device or continuous subcutaneous insulin infusion can preserve vision in selected cases.8,12,13
FDR的并发症有VH、牵引性RD、新生血管性青光眼和短时间失明,如几周或几个月。因此,为了防止FDR的破坏性后果,该疾病的管理包括早期诊断和广泛的泛视网膜光凝(PRPC)的积极治疗,必要时,早期的玻璃体切割(PPV)。1,2,6-8如果没有观察到明显的纤维血管玻璃体视网膜牵拉,应考虑玻璃体内抗vegf药物和类固醇注射作为辅助治疗,以使PRFC和PPV的NV消退和介入容易。最近关于FDR治疗的报道显示,垂体消融、胰岛素输注装置或持续皮下胰岛素输注可以在特定病例中保留视力8,12,13
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引用次数: 0
The masquerading squamous cell carcinoma 伪装性鳞状细胞癌
Pub Date : 2018-07-18 DOI: 10.15406/AOVS.2018.08.00305
P. Dhir, Dipankar Das, Balmukund Agarwal, K. Bhattacharjee, D. Misra, P. Deka, Awaneesh Upadhyay, Pranjal Mishra, Apurba Deka
This 36year-old male patient presented to us with pain & redness in right eye (OD) since last 2months and decreased vision since childhood attributed to injury with stone. Best corrected visual acuity (BCVA) in OD was counting fingers @3mt & in left eye (OS) 20/60. Slit lamp examination revealed conjunctival congestion in OD along with tissue growth over corneal surface, pigments on corneal endothelium, quiet anterior chamber (AC), with clear lens. The growth had limbal fixity and was extending from 7 to 10 clock hours over lateral aspect of cornea without any prominent vasculature. Fundus examination showed para-foveal scarring. OS was unremarkable. Intra ocular pressure was 20 & 18mmHg respectively. Diagnosis of OD pterygium was made and patient underwent pterygium excision with conjunctival autograft. Histopathology was inconclusive. Postoperatively patient was on antibiotics, steroids and lubricants for period of 6weeks and doing well. Patient re-presented to us, 3months post surgery when he noticed an abnormal growth on temporal side of cornea.
这名36岁男性患者向我们提出右眼疼痛和发红(OD),自过去2个月以来,由于结石损伤,从小视力下降。OD患者的最佳矫正视力(BCVA)为数指3mt,左眼(OS)为20/60。裂隙灯检查显示角膜外缘结膜充血,角膜表面组织增生,角膜内皮色素增多,前房安静,晶状体清晰。生长具有边缘固结性,在角膜外侧延伸7 - 10小时,无明显血管。眼底检查显示中央凹旁瘢痕。操作系统并不出众。眼压分别为20和18mmHg。诊断为外伤性翼状胬肉,行翼状胬肉切除和自体结膜移植。组织病理学无定论。术后患者给予抗生素、类固醇及润滑剂治疗6周,恢复良好。术后3个月,患者再次就诊,发现角膜颞侧有异常生长。
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引用次数: 0
Visual outcome and major complications of extracapsular cataract extraction performed by resident physicians at a regional hospital in Brazil 由巴西一家地区医院的住院医师进行的白内障囊外摘除术的视力结果和主要并发症
Pub Date : 2018-07-11 DOI: 10.15406/AOVS.2018.08.00304
C. M. Gomes, C. G. Filho, B. Valbon, R. P. Oliveira
Many studies have examined the outcomes and complication rates associated with cataract surgery performed by residents and have concluded that, overall, the complication rates and outcomes are acceptable.1,4 However, few of these studies have attempted to identify a time point during training or a surgical case number at which most residents become competent in performing extracapsular cataract extraction (ECCE). We designed a study to analyze the factors involved in major surgical complications and visual outcome of ECCE done by resident surgeons in a regional hospital.The purposes of this study were to analyze outcomes of ECCE performed by residents during their training experience and to determine a resident learning curve for this procedure.
许多研究调查了住院医师白内障手术的结果和并发症发生率,并得出结论,总的来说,并发症发生率和结果是可以接受的。然而,这些研究中很少有人试图确定培训期间的时间点或手术病例数,在这个时间点上,大多数住院医生能够胜任进行白内障囊外摘除术(ECCE)。我们设计了一项研究来分析一家地区医院住院医师所做的ECCE的主要手术并发症和视觉结果的相关因素。本研究的目的是分析住院医师在培训期间进行ECCE的结果,并确定住院医师对该程序的学习曲线。
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引用次数: 0
Abnormalities in higher cortical visual processing 高级皮质视觉处理异常
Pub Date : 2018-07-11 DOI: 10.15406/aovs.2018.08.00303
B. Turgut, Feyza Çaliş Karanfil, Fatos Altun Turgut
Sixty percent of the human brain is formed by visual pathways and high visual centers. Thirty visual centers work normally in concordance with systematic and constant communication with each other. Visual cortical areas include primary and secondary areas. Normal visual processing includes the signalization and neuronal processing initiated from the retina through the lateral geniculate body to the striate cortex.1,2 Visual cortical areas include Broadman-17 (primary visual cortex, area striata, visual area V1) area related to shape and size of the objects in striate cortex at lobus occipitalis; Broadman-18 (area parastriata, prestriate cortex, visual area V2) area related to the analysis of object motion in parastriate cortex at lobus occipitalis; Broadman-19 associated with visual area V3 in posterior parietal lobe related to visual integration and cortical color vision; V4 and V5 areas in superior temporal sulcus, related to motion perception (M cells) input, direction and depth perception; visual area V6 in parietal cortex associated with extra-personal perception.2,3 Lesions in visual areas 18 and 19 are associated with visual agnosia. The injury in left may be associated with pure alexia. Defects in the posterior parietal cortex cause optic ataxia while the damage to the medial supero-temporal cortex and medial temporal visual cortex results in loss of visual motion perception (akinetopsia) in different directions. The damage to the inferotemporal cortex causes visual agnosia. Damage to V4 results in loss of color vision, achromatopsia, while damage to V6 causes an inability to distinguish two-dimensional patterns.4–6
人类大脑的百分之六十是由视觉通路和高级视觉中枢组成的。三十个视觉中心正常工作,彼此之间系统而持续地沟通。视觉皮质区包括主要和次要区域。正常的视觉处理包括从视网膜通过外侧膝状体到纹状皮层的信号和神经元处理。1,2视觉皮质区包括枕叶纹状皮层与物体形状和大小有关的Broadman-17(初级视觉皮层、纹状区、V1视觉区)区;枕叶旁栏状皮层中与物体运动分析相关的Broadman-18(旁栏状区、前栏状皮层、视觉区V2)区;与视觉整合和皮层色觉相关的后顶叶V3视觉区相关的Broadman-19;颞上沟V4和V5区,与运动感知(M细胞)输入、方向和深度感知有关;顶叶皮层V6视觉区与超个人知觉有关。2、3视觉区18和19的病变与视觉失认有关。左侧损伤可能与单纯失读症有关。后顶叶皮层缺损引起视共济失调,内侧颞上皮层和内侧颞视觉皮层损伤导致不同方向的视觉运动知觉丧失(动位失视)。颞下皮层的损伤会导致视觉失认症。V4受损导致色盲,而V6受损导致无法区分二维图案
{"title":"Abnormalities in higher cortical visual processing","authors":"B. Turgut, Feyza Çaliş Karanfil, Fatos Altun Turgut","doi":"10.15406/aovs.2018.08.00303","DOIUrl":"https://doi.org/10.15406/aovs.2018.08.00303","url":null,"abstract":"Sixty percent of the human brain is formed by visual pathways and high visual centers. Thirty visual centers work normally in concordance with systematic and constant communication with each other. Visual cortical areas include primary and secondary areas. Normal visual processing includes the signalization and neuronal processing initiated from the retina through the lateral geniculate body to the striate cortex.1,2 Visual cortical areas include Broadman-17 (primary visual cortex, area striata, visual area V1) area related to shape and size of the objects in striate cortex at lobus occipitalis; Broadman-18 (area parastriata, prestriate cortex, visual area V2) area related to the analysis of object motion in parastriate cortex at lobus occipitalis; Broadman-19 associated with visual area V3 in posterior parietal lobe related to visual integration and cortical color vision; V4 and V5 areas in superior temporal sulcus, related to motion perception (M cells) input, direction and depth perception; visual area V6 in parietal cortex associated with extra-personal perception.2,3 Lesions in visual areas 18 and 19 are associated with visual agnosia. The injury in left may be associated with pure alexia. Defects in the posterior parietal cortex cause optic ataxia while the damage to the medial supero-temporal cortex and medial temporal visual cortex results in loss of visual motion perception (akinetopsia) in different directions. The damage to the inferotemporal cortex causes visual agnosia. Damage to V4 results in loss of color vision, achromatopsia, while damage to V6 causes an inability to distinguish two-dimensional patterns.4–6","PeriodicalId":90420,"journal":{"name":"Advances in ophthalmology & visual system","volume":"1 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2018-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88409868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Posterior reversible encephalopathy syndrome presenting as bilateral blindness in a post partum female 后可逆性脑病综合征表现为双侧失明产后妇女
Pub Date : 2018-07-03 DOI: 10.15406/aovs.2018.08.00302
S. Ramakrishna, S. Rao, A. Singal
Posterior reversible encephalopathy syndrome (PRES) is a clinic radiological entity that was first reported by Hinchey et al.,1 in 1996 based on 15 cases. He described it as white matter edema presenting with headache, altered mental functioning, seizures, and abnormalities of visual perception. This condition has been called previously by several terms such as reversible posterior cerebral edema syndrome, reversible posterior leukoencephalopathy syndrome, and reversible occipital parietal encephalopathy. It was Stott et al.,2 who proposed the term Posterior reversible encephalopathy syndrome (PRES) for the condition. PRES is characterized by visual abnormalities, loss of consciousness, seizures, consciousness, headaches and focal neurological signs. Causes of PRES are diverse and include preeclampsia, eclampsia, renal insufficiency, solid organ transplantation and immunosuppressive therapy.3 Some relatively rarer causes include use of bevacizumab, head injury, seizure and migraine.4 Though several cases of PRES have been reported in neurology and neuroradiology, ophthalmic literature has had limited exposure and this case report tries to describe a common presentation of PRES along with its management. Case report
后可逆性脑病综合征(Posterior reversible enceopathy syndrome, PRES)是一种临床放射学疾病,1996年由Hinchey等人1在15例病例的基础上首次报道。他将其描述为白质水肿,表现为头痛、精神功能改变、癫痫发作和视觉感知异常。这种疾病以前被称为可逆性后脑水肿综合征、可逆性后脑白质病综合征和可逆性枕顶叶脑病。Stott等人2提出了后路可逆性脑病综合征(PRES)这个术语。PRES的特征是视觉异常、意识丧失、癫痫发作、意识丧失、头痛和局灶性神经症状。PRES的病因多种多样,包括先兆子痫、子痫、肾功能不全、实体器官移植和免疫抑制治疗一些相对罕见的原因包括使用贝伐单抗、头部损伤、癫痫发作和偏头痛虽然在神经病学和神经放射学中已经报道了几例PRES,但眼科文献的曝光有限,本病例报告试图描述PRES的常见表现及其治疗。病例报告
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引用次数: 0
Clinical peculiarities in challenging cases of atypical retinitis pigmentosa: a case series and review of the literature 具有挑战性的非典型视网膜色素变性病例的临床特点:病例系列和文献综述
Pub Date : 2018-06-20 DOI: 10.15406/AOVS.2018.08.00300
Saurabh Deshmukh, Hemalata Deka, H. Bhattacharjee, Dipankar Das, Krati Gupta
We report three distinct cases who presented initially as age-related macular degeneration, intermediate uveitis, and cystoid macular edema respectively. They were later diagnosed to have atypical retinitis pigmentosa. Clinical presentation, full field perimetry, fundus photography, electroretinography, fundus fluorescein angiography and optical coherence tomography are described in detail for all three patients. The course of their disease and treatment during the period of observation are discussed with complete photo-documentation. Since the fundus may appear clinically normal in such cases, the diagnosis may be missed. So, these cases pose a diagnostic challenge to the ophthalmologist.
我们报告三个不同的病例,最初分别表现为年龄相关性黄斑变性、中度葡萄膜炎和囊样黄斑水肿。他们后来被诊断为非典型色素性视网膜炎。临床表现,全视野视野检查,眼底摄影,视网膜电图,眼底荧光素血管造影和光学相干断层扫描详细描述了这三个病人。对观察期间的病程和治疗进行了完整的照片记录。由于这些病例的眼底在临床上可能表现正常,因此可能漏诊。因此,这些病例对眼科医生的诊断提出了挑战。
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引用次数: 2
Evidence of zonular stress lines on human crystalline lens 人类晶状体上带状应力线的证据
Pub Date : 2018-06-15 DOI: 10.15406/aovs.2018.08.00299
Dipankar Das, H. Bhattacharjee, D. Misra, P. Deka, Fazil Khurrum, Saurabh Deshmukh, P. Mishra, Priya T. Bhola, Apurba Deka
The lens is an extremely planned system of focused cells which constitutes an important element of optical arrangement of the eye and fulfills the important functions of altering the refractive index of light entering the eye to focus on the retina.1,2 The transparency of lens is due to the shape, array, internal structure, and biochemistry of the lens cells or lens fibre.1 The lens is held in place by composite three dimensional systems of radially arranged zonules called zonules of Zinn or the suspensory ligament of the lens.1 These fragile fibres are attached to the lens capsule 2mm anterior and 1mm posterior to the equator and arise from the region of pars plana ciliary epithelium and pass forward closely related to the lateral surfaces of ciliary processes.1 The fibrous zonules blend with basal lamina of the lens capsule. The anterior and posterior zonules place in obliquely into superficial 1-2μm of preand post-equatorial lens capsule, while equatorial zonules insert at right angles.1–3 We present the documentation of zonular stress lines (ZSLs) for the first time in the scientific literature on the transparent crystalline lens from three enucleated eyeballs. These stress lines are the evidence of the zonules to take part in accommodation and also arbitrate accommodative movements. Although some believed that there are two types of zonules, first being ‘main zonules’ and other the ‘tension zonules’, the later being placed under tension during accommodation but there were no morphological different stress lines on the surface of lens in so called two varieties of zonules.1–3
晶状体是一个由聚焦细胞组成的高度规划的系统,它构成了眼睛光学结构的重要组成部分,并完成了改变进入眼睛的光线的折射率以聚焦在视网膜上的重要功能。1,2晶状体的透明度是由晶状体细胞或晶状体纤维的形状、排列、内部结构和生物化学决定的晶状体是由放射状排列的带状晶状体或晶状体悬韧带组成的复合三维系统固定的这些脆弱的纤维附着在距赤道前2mm和后1mm的晶状体囊上,起源于睫状体平部睫状体上皮区域,并向前延伸,与睫状体突的外侧表面密切相关纤维带与晶状体囊的基底层混合。前、后带状晶状体斜插于前、后赤道晶状体囊表面1 ~ 2μm处,赤道带状晶状体呈直角插入。1-3我们首次在科学文献中报道了来自三个去核眼球的透明晶状体的带状应力线(ZSLs)。这些应力线是区域参与调节和仲裁调节运动的证据。虽然有人认为存在两种类型的小带,一种是“主小带”,另一种是“张力小带”,后者在调节过程中处于张力状态,但所谓的两种小带在晶状体表面没有形态上的不同应力线
{"title":"Evidence of zonular stress lines on human crystalline lens","authors":"Dipankar Das, H. Bhattacharjee, D. Misra, P. Deka, Fazil Khurrum, Saurabh Deshmukh, P. Mishra, Priya T. Bhola, Apurba Deka","doi":"10.15406/aovs.2018.08.00299","DOIUrl":"https://doi.org/10.15406/aovs.2018.08.00299","url":null,"abstract":"The lens is an extremely planned system of focused cells which constitutes an important element of optical arrangement of the eye and fulfills the important functions of altering the refractive index of light entering the eye to focus on the retina.1,2 The transparency of lens is due to the shape, array, internal structure, and biochemistry of the lens cells or lens fibre.1 The lens is held in place by composite three dimensional systems of radially arranged zonules called zonules of Zinn or the suspensory ligament of the lens.1 These fragile fibres are attached to the lens capsule 2mm anterior and 1mm posterior to the equator and arise from the region of pars plana ciliary epithelium and pass forward closely related to the lateral surfaces of ciliary processes.1 The fibrous zonules blend with basal lamina of the lens capsule. The anterior and posterior zonules place in obliquely into superficial 1-2μm of preand post-equatorial lens capsule, while equatorial zonules insert at right angles.1–3 We present the documentation of zonular stress lines (ZSLs) for the first time in the scientific literature on the transparent crystalline lens from three enucleated eyeballs. These stress lines are the evidence of the zonules to take part in accommodation and also arbitrate accommodative movements. Although some believed that there are two types of zonules, first being ‘main zonules’ and other the ‘tension zonules’, the later being placed under tension during accommodation but there were no morphological different stress lines on the surface of lens in so called two varieties of zonules.1–3","PeriodicalId":90420,"journal":{"name":"Advances in ophthalmology & visual system","volume":"74 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76836107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Advances in ophthalmology & visual system
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