Ajmain Ishaat Khan, F. Aktar, J. A. Chowdhury, A. A. Chowdhury, Shaila Kabir, Md. Shah Amran
Turmeric, or Curcuma longa, has been used widely in Indian subcontinental cuisine, cosmetics, preservatives, and ceremonial purposes. Turmeric has long been used to cure a variety of conditions, including allergies, indigestion, coughing, and other illnesses. This review attempts to close the knowledge gap about the wider range of medical applications of Curcuma longa, with a special emphasis on the pharmacological characteristics of its main ingredients, curcuminoids and essential oils. Turmeric has shown encouraging therapeutic results in recent trials, most notably in the treatment of rheumatoid arthritis, cancer, diabetes, hyperlipidemia, inflammation, microbiological infections, asthma, snake bites, and Alzheimer's disease. The review objectively evaluates the data pertaining to these assertions, emphasizing aromatic-turmerone and curcumin as main active ingredients. Through a methodical examination of existing literature, this review highlights the possibility of developing turmeric-based novel drugs for modern medicine, thereby contributing to improved health outcomes and quality of life. J. Bio-Sci. 31(2): 67-85, 2023
{"title":"A Comprehensive Study on Biology, Chemistry and Pharmacology of Curcuma Longa L.- A Review","authors":"Ajmain Ishaat Khan, F. Aktar, J. A. Chowdhury, A. A. Chowdhury, Shaila Kabir, Md. Shah Amran","doi":"10.3329/jbs.v31i2.74148","DOIUrl":"https://doi.org/10.3329/jbs.v31i2.74148","url":null,"abstract":"Turmeric, or Curcuma longa, has been used widely in Indian subcontinental cuisine, cosmetics, preservatives, and ceremonial purposes. Turmeric has long been used to cure a variety of conditions, including allergies, indigestion, coughing, and other illnesses. This review attempts to close the knowledge gap about the wider range of medical applications of Curcuma longa, with a special emphasis on the pharmacological characteristics of its main ingredients, curcuminoids and essential oils. Turmeric has shown encouraging therapeutic results in recent trials, most notably in the treatment of rheumatoid arthritis, cancer, diabetes, hyperlipidemia, inflammation, microbiological infections, asthma, snake bites, and Alzheimer's disease. The review objectively evaluates the data pertaining to these assertions, emphasizing aromatic-turmerone and curcumin as main active ingredients. Through a methodical examination of existing literature, this review highlights the possibility of developing turmeric-based novel drugs for modern medicine, thereby contributing to improved health outcomes and quality of life.\u0000J. Bio-Sci. 31(2): 67-85, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":" 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The global population is steadily increasing, including in Bangladesh, and this necessitates the exploration of new technologies to meet the future demand for fish and biofloc technology holds great potential. Unfortunately, there is a dearth of information regarding biofloc culture technology in Bangladesh. Therefore, the purpose of this study was to identify a suitable probiotic for achieving rapid floc maturation. The research was taking place at the Pran Fisheries Project located in Razapur village, under the Sreemangal Upazilla in the Moulvibazar district, from 01 October to 15 October 2021. Thus, four different probiotics, namely Everfresh-Pro, PondCare-3S, Profs, and MI Plus, were tested and each one exhibited distinct mean value. Throughout the floc maturation process, consistent conditions were maintained, including a temperature range of 27-30°C, dissolved oxygen (DO) levels of 6 ppm, pH of 7.8, total dissolved solids (TDS) concentration of 980 ppm, and salinity of 0.8 ppt for all probiotics. The results revealed flocculation measurements of 28 mL for Everfresh-Pro, 23 mL for PondCare-3S, 20 mL for Profs, and 15 mL for MI Plus, as determined by the Imhoff Cone. The utilization of Everfresh-Pro probiotic results in a shorter FCO (Fermented Carbon Organic) production time among the other probiotics within biofloc system. These findings emphasize the significant potential of employing suitable probiotics in FCO making process, as it can substantially reduce maturation time and enhance the quality of floc, ultimately leading to more efficient and effective aquaculture practice through biofloc technology. J. Bio-Sci. 31(2): 1-12, 2023
{"title":"Screening Commercial Probiotic Products for Enhancing Floc Maturation in Biofloc System","authors":"-. Kamruzzaman, Mst. Shahinur Khatun, Taiba Akter Laboni, Md. Ashekur Rahman, Md Harun, Obaidur Rahman, Md. Akhtarul Islam, Md Mahabubur Rahman Rahman, M. Y. Hossain","doi":"10.3329/jbs.v31i2.74141","DOIUrl":"https://doi.org/10.3329/jbs.v31i2.74141","url":null,"abstract":"The global population is steadily increasing, including in Bangladesh, and this necessitates the exploration of new technologies to meet the future demand for fish and biofloc technology holds great potential. Unfortunately, there is a dearth of information regarding biofloc culture technology in Bangladesh. Therefore, the purpose of this study was to identify a suitable probiotic for achieving rapid floc maturation. The research was taking place at the Pran Fisheries Project located in Razapur village, under the Sreemangal Upazilla in the Moulvibazar district, from 01 October to 15 October 2021. Thus, four different probiotics, namely Everfresh-Pro, PondCare-3S, Profs, and MI Plus, were tested and each one exhibited distinct mean value. Throughout the floc maturation process, consistent conditions were maintained, including a temperature range of 27-30°C, dissolved oxygen (DO) levels of 6 ppm, pH of 7.8, total dissolved solids (TDS) concentration of 980 ppm, and salinity of 0.8 ppt for all probiotics. The results revealed flocculation measurements of 28 mL for Everfresh-Pro, 23 mL for PondCare-3S, 20 mL for Profs, and 15 mL for MI Plus, as determined by the Imhoff Cone. The utilization of Everfresh-Pro probiotic results in a shorter FCO (Fermented Carbon Organic) production time among the other probiotics within biofloc system. These findings emphasize the significant potential of employing suitable probiotics in FCO making process, as it can substantially reduce maturation time and enhance the quality of floc, ultimately leading to more efficient and effective aquaculture practice through biofloc technology.\u0000J. Bio-Sci. 31(2): 1-12, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":" 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saurav Brata Das, Md Shahidul Islam, M. N. Uddin, Bani Krishna Goswami, S. M. S. Abedin, Md Abdul Baki
The experiment was carried out at the Olericulture division of the Bangladesh Agricultural Research Institute's experimental field in Joydebpur, Gazipur. The objective was to evaluate the performance of eleven potential inbreed lines (CLN-3849, CLN-3850, CLN-3859, CLN-3860, CLN-3862, CLN-3864, CLN-3906, CLN-3916, CLN-3735, CLN-3791, CLN-3792) along with BARI Hybrid Tomato-8. Data on different parameters such as, plant height (cm), days to 50% flowering, individual fruit weight, fruit length, fruit breadth, locules number per fruit, Total Soluble Solids (TSS), pericarp thickness (cm), number of fruits per plant and fruit yield per plant were measured. Significant differences were observed in terms of plant height, days to 50% flowering, single fruit weight, number of locules and pericarp thickness among the genotypes. The outcome showed that the 12 tomato genotypes varied in the quantity of fruits produced per plant. Number of fruits per plant of different tomato line ranged from 7.33 to 21.67. It was found that the genotype BARI Hybrid Tomato-8 had maximum number of fruits per plant (21.67) followed by CLN-3791 (18.33) whereas the inbred line CLN-3791 produced maximum quantity of fruits (1.616 kg/plant). J. Bio-Sci. 31(2): 13-23, 2023
该实验在孟加拉国农业研究所（Bangladesh Agricultural Research Institute）位于加济布尔（Gazipur）乔伊德布尔（Joydebpur）的试验田的油菜栽培部门（Olericulture division）进行。目的是评估 11 个潜在近交系（CLN-3849、CLN-3850、CLN-3859、CLN-3860、CLN-3862、CLN-3864、CLN-3906、CLN-3916、CLN-3735、CLN-3791、CLN-3792）和 BARI 杂交番茄-8 的表现。对不同参数的数据进行了测量，如株高（厘米）、开花至 50% 的天数、单果重、果实长度、果实宽度、每个果实的子房室数、总可溶性固形物（TSS）、果皮厚度（厘米）、每株果实数和每株果实产量。在株高、50%开花天数、单果重、子房室数和果皮厚度方面，各基因型之间存在显著差异。结果表明，12 个番茄基因型的单株果实产量各不相同。不同番茄品系的单株果实数从 7.33 个到 21.67 个不等。结果发现，基因型 BARI Hybrid Tomato-8 的单株结果数最多（21.67 个），其次是 CLN-3791（18.33 个），而近交系 CLN-3791 的结果数最多（1.616 公斤/株）：13-23, 2023
{"title":"Evaluation of the Performance of Summer Tomato Lines in Bangladesh Conditions","authors":"Saurav Brata Das, Md Shahidul Islam, M. N. Uddin, Bani Krishna Goswami, S. M. S. Abedin, Md Abdul Baki","doi":"10.3329/jbs.v31i2.74142","DOIUrl":"https://doi.org/10.3329/jbs.v31i2.74142","url":null,"abstract":"The experiment was carried out at the Olericulture division of the Bangladesh Agricultural Research Institute's experimental field in Joydebpur, Gazipur. The objective was to evaluate the performance of eleven potential inbreed lines (CLN-3849, CLN-3850, CLN-3859, CLN-3860, CLN-3862, CLN-3864, CLN-3906, CLN-3916, CLN-3735, CLN-3791, CLN-3792) along with BARI Hybrid Tomato-8. Data on different parameters such as, plant height (cm), days to 50% flowering, individual fruit weight, fruit length, fruit breadth, locules number per fruit, Total Soluble Solids (TSS), pericarp thickness (cm), number of fruits per plant and fruit yield per plant were measured. Significant differences were observed in terms of plant height, days to 50% flowering, single fruit weight, number of locules and pericarp thickness among the genotypes. The outcome showed that the 12 tomato genotypes varied in the quantity of fruits produced per plant. Number of fruits per plant of different tomato line ranged from 7.33 to 21.67. It was found that the genotype BARI Hybrid Tomato-8 had maximum number of fruits per plant (21.67) followed by CLN-3791 (18.33) whereas the inbred line CLN-3791 produced maximum quantity of fruits (1.616 kg/plant).\u0000J. Bio-Sci. 31(2): 13-23, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":" 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Azizul Islam, Md Jawadul Haque, Mokther Hossain, S. S. Islam
The most often diagnosed diseases in males, prostate cancer (Ca-P) is now the third most common malignancy to cause mortality in different countries of the world. Data showed that serum PSA and prostate volume were demonstrated a substantial log-linear association with age. Numerous studies have demonstrated that the level of fPSA and the ratio of fPSA/total PSA can distinguish between benign and malignant prostatic diseases, with much lower levels in patients with prostate cancer. In a group of 681 LUTS patients, researcher assessed total PSA, fPSA, and prostate volume. The prostate volume significantly correlated with both total serum PSA and free PSA, with r = 0.51 (p<0.001) and r = 0.61 (p<0.001), respectively. In the range of 10% to 20% of the observed prostate volume, fPSA produced 67% of the anticipated values and 91.2% of the actual results. For intervals of between 10% and 20%, total serum PSA was predicted to increase at rates of 63.0% and 90.9%, respectively. It is known that early-stage prostate cancer tumours release PSA, which can be used as a biomarker to track treatment response and disease progression and to help doctors make treatment decisions. Data shows before surgery, PSA levels can be used to forecast how radical prostatectomy would turn out. Preoperative PSA levels were substantially correlated with advanced, high-grade illness and biochemical markers. The usefulness of PSA as a prognostic indicator declines with prostate cancer progression. As the disease progresses, prostate cancer tumours become significantly more heterogeneous, both between patients and, crucially, within the same patient. This causes variation in tumour PSA expression, which may cause false positive or false negative PSA test findings. In symptomatic patients, PSA has a high sensitivity and a low specificity for the detection of prostate cancer. There is an urgent need for research into the usefulness of PSA for the detection of clinically relevant prostate cancer in primary care. J. Bio-Sci. 31(2): 56-66, 2023
{"title":"Detection of Prostate Cancer and Benign Prostatic Hyperplasia Using Prostate-Specific Antigen Testing: A Review of Clinical Research Studies","authors":"Md Azizul Islam, Md Jawadul Haque, Mokther Hossain, S. S. Islam","doi":"10.3329/jbs.v31i2.74147","DOIUrl":"https://doi.org/10.3329/jbs.v31i2.74147","url":null,"abstract":"The most often diagnosed diseases in males, prostate cancer (Ca-P) is now the third most common malignancy to cause mortality in different countries of the world. Data showed that serum PSA and prostate volume were demonstrated a substantial log-linear association with age. Numerous studies have demonstrated that the level of fPSA and the ratio of fPSA/total PSA can distinguish between benign and malignant prostatic diseases, with much lower levels in patients with prostate cancer. In a group of 681 LUTS patients, researcher assessed total PSA, fPSA, and prostate volume. The prostate volume significantly correlated with both total serum PSA and free PSA, with r = 0.51 (p<0.001) and r = 0.61 (p<0.001), respectively. In the range of 10% to 20% of the observed prostate volume, fPSA produced 67% of the anticipated values and 91.2% of the actual results. For intervals of between 10% and 20%, total serum PSA was predicted to increase at rates of 63.0% and 90.9%, respectively. It is known that early-stage prostate cancer tumours release PSA, which can be used as a biomarker to track treatment response and disease progression and to help doctors make treatment decisions. Data shows before surgery, PSA levels can be used to forecast how radical prostatectomy would turn out. Preoperative PSA levels were substantially correlated with advanced, high-grade illness and biochemical markers. The usefulness of PSA as a prognostic indicator declines with prostate cancer progression. As the disease progresses, prostate cancer tumours become significantly more heterogeneous, both between patients and, crucially, within the same patient. This causes variation in tumour PSA expression, which may cause false positive or false negative PSA test findings. In symptomatic patients, PSA has a high sensitivity and a low specificity for the detection of prostate cancer. There is an urgent need for research into the usefulness of PSA for the detection of clinically relevant prostate cancer in primary care.\u0000J. Bio-Sci. 31(2): 56-66, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":" 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leaf spot disease is considered as one of the devastating disease of garlic that results in significant decrease of crop yield worldwide. The main purpose of this study was to identify the pathogenic fungi of garlic and to find out its eco-friendly control measures. The pathogen (Alternaria alternata) was characterized morphologically and identified through the molecular method. Morphological characters e.g. greyish-black mycelium and unbranched, straight, smooth-walled, and golden brown conidia was identified as the initial indicator. Species level identification was carried out by using sequence analysis of internal transcribed spacer/5.8S ribosomal DNA (rDNA) in which internal transcribed spacer 4 (ITS4) and ITS5 and 5.8S rDNA were amplified by PCR. The results revealed that Potato Dextrose Agar (91 mm) is the best media for the mycelial growth of A. alternata followed by Potato Sucrose Agar and Carrot Agar (55 mm). The best growth was found at 30℃ at pH 6. A. alternata can be controlled biologically with a mix-culture of different species of Trichoderma as T. harzianum, T. reseei, T. asperellum. Culture with two or more species had better inhibitory effects than culture with one species. Lawsonia inermis and Ocimum sanctum extract showed a certain level of significant inhibition against A. alternata, (73.74% and 65.93% respectively). Thus, the present study will be helpful to identify the pathogen of leaf spot disease of garlic and eco-friendly management of the disease in future. J. Bio-Sci. 31(2): 45-53, 2023
{"title":"Molecular Identification of Alternaria Alternata Associated With Leaf Spot Disease in Garlic and Its Eco-Friendly Control Measures","authors":"Most Shahida Khatun, Md Abu Rayhan, Nuhu Alam","doi":"10.3329/jbs.v31i2.74146","DOIUrl":"https://doi.org/10.3329/jbs.v31i2.74146","url":null,"abstract":"Leaf spot disease is considered as one of the devastating disease of garlic that results in significant decrease of crop yield worldwide. The main purpose of this study was to identify the pathogenic fungi of garlic and to find out its eco-friendly control measures. The pathogen (Alternaria alternata) was characterized morphologically and identified through the molecular method. Morphological characters e.g. greyish-black mycelium and unbranched, straight, smooth-walled, and golden brown conidia was identified as the initial indicator. Species level identification was carried out by using sequence analysis of internal transcribed spacer/5.8S ribosomal DNA (rDNA) in which internal transcribed spacer 4 (ITS4) and ITS5 and 5.8S rDNA were amplified by PCR. The results revealed that Potato Dextrose Agar (91 mm) is the best media for the mycelial growth of A. alternata followed by Potato Sucrose Agar and Carrot Agar (55 mm). The best growth was found at 30℃ at pH 6. A. alternata can be controlled biologically with a mix-culture of different species of Trichoderma as T. harzianum, T. reseei, T. asperellum. Culture with two or more species had better inhibitory effects than culture with one species. Lawsonia inermis and Ocimum sanctum extract showed a certain level of significant inhibition against A. alternata, (73.74% and 65.93% respectively). Thus, the present study will be helpful to identify the pathogen of leaf spot disease of garlic and eco-friendly management of the disease in future.\u0000J. Bio-Sci. 31(2): 45-53, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Nahid Islam Chowdhury, Md Anayet Ullah Ullah, Md Belal Hossain, S. M. S. Islam
Congenital heart disease (CHD) is the most common congenital cardiac defect in children. It is a significant cause to infant death and morbidity. This article provides an overview of the etiology and epidemiology of CHD. According to the WHO, Bangladesh has a 6% incidence of congenital heart disease. Nine frequent lesions make up 80% of congenital heart disease. The majority of the rare or complex lesions that make up the remaining 20% of congenital heart disease. The study aims to contribute to overview of CHD enhancing patient outcomes and informing public health policies. This review study employs a systematic review approach to compile and analyze existing research on children with suspected congenital heart disease. We looked at recent studies, and searched pub med, Cochrane database, cardiovascular disease journal. The data mainly involve a review of CHD from various studies of sample groups of different ethnicities; age groups and gender were evaluated. After the application of predefined inclusion/exclusion criteria, 50 studies were included in the systematic review. CHD impacts millions of women worldwide children suffer silently without knowing that there is treatment. CHD are revealed by epidemiology research which must recognize the value of routine medical exams, with the help of successful transition program. A thorough review of the most recent research on the pathophysiology, Incidences clinical symptoms, and therapy of CHD was conducted and optimum care of CHD is essential to enhance the quality of life and prevent the progression of the diseases. J. Bio-Sci. 31(2): 87-101, 2023
{"title":"Children With Suspected Congenital Heart Disease - A Review","authors":"Md Nahid Islam Chowdhury, Md Anayet Ullah Ullah, Md Belal Hossain, S. M. S. Islam","doi":"10.3329/jbs.v31i2.74149","DOIUrl":"https://doi.org/10.3329/jbs.v31i2.74149","url":null,"abstract":"Congenital heart disease (CHD) is the most common congenital cardiac defect in children. It is a significant cause to infant death and morbidity. This article provides an overview of the etiology and epidemiology of CHD. According to the WHO, Bangladesh has a 6% incidence of congenital heart disease. Nine frequent lesions make up 80% of congenital heart disease. The majority of the rare or complex lesions that make up the remaining 20% of congenital heart disease. The study aims to contribute to overview of CHD enhancing patient outcomes and informing public health policies. This review study employs a systematic review approach to compile and analyze existing research on children with suspected congenital heart disease. We looked at recent studies, and searched pub med, Cochrane database, cardiovascular disease journal. The data mainly involve a review of CHD from various studies of sample groups of different ethnicities; age groups and gender were evaluated. After the application of predefined inclusion/exclusion criteria, 50 studies were included in the systematic review. CHD impacts millions of women worldwide children suffer silently without knowing that there is treatment. CHD are revealed by epidemiology research which must recognize the value of routine medical exams, with the help of successful transition program. A thorough review of the most recent research on the pathophysiology, Incidences clinical symptoms, and therapy of CHD was conducted and optimum care of CHD is essential to enhance the quality of life and prevent the progression of the diseases.\u0000J. Bio-Sci. 31(2): 87-101, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141677529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Saif Zaman Zaman, Parvez Hassan Hassan, S M Shahinul Islam Islam, Md Anayet Ullah Ullah, Md Golam Rabbani Rabbani
The goal of the present study was to examine how well three distinct kinds of anti-diabetic drugs- insulin, biguanides and sulfonylureas performed in Bangladeshi patients who had recently been diagnosed with diabetes mellitus. This was an observational study and carried out on 102 patients admitted in different hospitals in Rajshahi, Bangladesh during the study period. Majority (32.02%) respondents belonged to 51-60 years age group, followed by 41-50 years and the least >60 years age group viz. 7.19%. Female preponderance was noticed in the study population where 59.80% were females; whereas 40.20% males. Results of distribution of respondents based on residence and class of anti-diabetic medication use showed in insulin receiving group 66.67% were urban people and 33.33% were rural resident; biguanides receiving groups 64.71% were urban resident and 35.29% were rural resident; sulfonylureas receiving groups 58.82% were urban resident and 41.18% were rural residents. Data on participant’s lifestyle and smoking habit showed lifestyle of 65.70% patients were sedentary and 34.30% were active and according to smoking habit of the patients 14% were smokers while 86% were non-smokers. Family history of DM among the patients showed 17% had familial history and 83% did not have. Data showed that the patients taken insulin, biguanides and sulfonylurea as with BMI were mostly in 18.50 - 24.99 with p-value 0.621. Although no statistically significant difference was noticed among the groups regarding treatment response of three drugs (p = 0.252, 0.284, 0.675 for HbA1c, FBS and PPBS respectively) after 3 months follow-up of medication use and (p = 0.284, 0.323, 0.817 for HbA1c, FBS and PPBS respectively) after 6 months follow-up. However, p-value was not significant but insulin receiving patients had relatively better treatment response than biguanide receiving group than sulfonylurea receiving group at 3rd and 6th month. In insulin receiving group 90.19 % had desired glycemic control. In biguanide receiving group 76.47 % had desired glycemic control. In sulfonylurea receiving group 84.31 % had desired glycemic control. So it appears that insulin provides the best glycemic control followed by sulfonylurea and the biguanides are relativity less potent in glycemic control of newly diagnosed patients in our study area. In this study, the sample size was quite small, which may not represent the whole population and the research used purposeful sampling, which may have skewed the results. J. Bio-Sci. 31(1): 39-49, 2023
{"title":"Comparative Efficacy of Insulin, Biguanides and Sulfonylureas In The Glycemic Control of Newly Diagnosed Diabetes Mellitus Patients in Rajshahi, Bangladesh","authors":"Md Saif Zaman Zaman, Parvez Hassan Hassan, S M Shahinul Islam Islam, Md Anayet Ullah Ullah, Md Golam Rabbani Rabbani","doi":"10.3329/jbs.v31i1.69533","DOIUrl":"https://doi.org/10.3329/jbs.v31i1.69533","url":null,"abstract":"The goal of the present study was to examine how well three distinct kinds of anti-diabetic drugs- insulin, biguanides and sulfonylureas performed in Bangladeshi patients who had recently been diagnosed with diabetes mellitus. This was an observational study and carried out on 102 patients admitted in different hospitals in Rajshahi, Bangladesh during the study period. Majority (32.02%) respondents belonged to 51-60 years age group, followed by 41-50 years and the least >60 years age group viz. 7.19%. Female preponderance was noticed in the study population where 59.80% were females; whereas 40.20% males. Results of distribution of respondents based on residence and class of anti-diabetic medication use showed in insulin receiving group 66.67% were urban people and 33.33% were rural resident; biguanides receiving groups 64.71% were urban resident and 35.29% were rural resident; sulfonylureas receiving groups 58.82% were urban resident and 41.18% were rural residents. Data on participant’s lifestyle and smoking habit showed lifestyle of 65.70% patients were sedentary and 34.30% were active and according to smoking habit of the patients 14% were smokers while 86% were non-smokers. Family history of DM among the patients showed 17% had familial history and 83% did not have. Data showed that the patients taken insulin, biguanides and sulfonylurea as with BMI were mostly in 18.50 - 24.99 with p-value 0.621. Although no statistically significant difference was noticed among the groups regarding treatment response of three drugs (p = 0.252, 0.284, 0.675 for HbA1c, FBS and PPBS respectively) after 3 months follow-up of medication use and (p = 0.284, 0.323, 0.817 for HbA1c, FBS and PPBS respectively) after 6 months follow-up. However, p-value was not significant but insulin receiving patients had relatively better treatment response than biguanide receiving group than sulfonylurea receiving group at 3rd and 6th month. In insulin receiving group 90.19 % had desired glycemic control. In biguanide receiving group 76.47 % had desired glycemic control. In sulfonylurea receiving group 84.31 % had desired glycemic control. So it appears that insulin provides the best glycemic control followed by sulfonylurea and the biguanides are relativity less potent in glycemic control of newly diagnosed patients in our study area. In this study, the sample size was quite small, which may not represent the whole population and the research used purposeful sampling, which may have skewed the results. J. Bio-Sci. 31(1): 39-49, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":"7 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135724748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mostofa Asif Anjum Anjum, Md Eram Hosen Hosen, Ariful Islam Hridoy Hridoy, Md Sojiur Rahman Rahman, Farhana Afroz Joty Joty, Md Khalekuzzaman, Md Asadul Islam Islam, Rashed Zaman Zaman
Hydroponics culture offers immense benefits in plant research, making it a valuable and versatile tool in scientific investigations across plant biology, agronomy, horticulture and diverse fields of research. The present study has been carried out for the establishment of Brassica alba and Solanum lycopersicum on hydroponic culture in laboratory condition. Firstly, an ideal concentration of macro and micro nutrients was developed for both B. alba and S. lycopersicum seedlings. After germination of both seeds, seedling was carefully monitored over a 15-day observation period on seedling tray. Then transfer of two-week-old seedlings to hydroponic media resulted in successful adaptation for both species. B. alba displayed slow initial growth but progressed significantly with robust development in the long run. In contrast, S. lycopersicum adapted quickly and exhibited continuous growth throughout the observation period. By week 4, both species had matured, with B. alba plants showing larger roots and stems and the onset of flowering. Both B. alba and S. lycopersicum seedlings displayed distinct growth patterns in hydroponic culture. These findings contribute valuable insights into the growth dynamics and viability of these two plant species in hydroponic systems, providing important information for optimizing cultivation practices and improving agricultural productivity. J. Bio-Sci. 31(1): 87-98, 2023
{"title":"Establishment and Maintenance of Brassica Alba and Solanum Lycopersicum on Hydroponic Culture at Laboratory Condition","authors":"Mostofa Asif Anjum Anjum, Md Eram Hosen Hosen, Ariful Islam Hridoy Hridoy, Md Sojiur Rahman Rahman, Farhana Afroz Joty Joty, Md Khalekuzzaman, Md Asadul Islam Islam, Rashed Zaman Zaman","doi":"10.3329/jbs.v31i1.69537","DOIUrl":"https://doi.org/10.3329/jbs.v31i1.69537","url":null,"abstract":"Hydroponics culture offers immense benefits in plant research, making it a valuable and versatile tool in scientific investigations across plant biology, agronomy, horticulture and diverse fields of research. The present study has been carried out for the establishment of Brassica alba and Solanum lycopersicum on hydroponic culture in laboratory condition. Firstly, an ideal concentration of macro and micro nutrients was developed for both B. alba and S. lycopersicum seedlings. After germination of both seeds, seedling was carefully monitored over a 15-day observation period on seedling tray. Then transfer of two-week-old seedlings to hydroponic media resulted in successful adaptation for both species. B. alba displayed slow initial growth but progressed significantly with robust development in the long run. In contrast, S. lycopersicum adapted quickly and exhibited continuous growth throughout the observation period. By week 4, both species had matured, with B. alba plants showing larger roots and stems and the onset of flowering. Both B. alba and S. lycopersicum seedlings displayed distinct growth patterns in hydroponic culture. These findings contribute valuable insights into the growth dynamics and viability of these two plant species in hydroponic systems, providing important information for optimizing cultivation practices and improving agricultural productivity. J. Bio-Sci. 31(1): 87-98, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135724763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lathyrus sativus L. causes lathyrism both in animals and human due to the presence of the neurotoxin β-ODAP (β -N-Oxalyl-L-α, β -diaminopropionic acid). This study was performed to find out the toxic effect of grass pea on onion root tip cells. The root lengths of onion were reduced as the concentrations of different plant parts extracts of grass pea increased. The percentages of chromosomal abnormalities, NV and ICV of onion root tip cells showed an increasing trend with the increasing of different extracts concentrations. The mitotic index and chromosomal abnormalities in treated onion root tip cells were significantly different than that of control. The mitotic index and chromosomal abnormalities had a reverse relationship. Almost all the treated root tip cells of onion showed this mito-depressive effect. From this findings, it may concluded that β -N-Oxayl-L- α, β-diaminopropionic acid (Lathyrogens) in Lathyrus sativus may be responsible for mitotic depression and chromosomal abnormalities on the root tip cells of onion. J. Bio-Sci. 31(1): 51-60, 2023
由于含有β- n -草酸- l -α， β-二氨基丙酸(β - n -草酸- l -α， β-二氨基丙酸)的神经毒素，Lathyrus sativus L.可引起动物和人的lathyrism。本文研究了草豆对洋葱根尖细胞的毒性作用。随着草豆不同植物部位提取物浓度的增加，洋葱的根长减小。随着不同提取物浓度的增加，洋葱根尖细胞的染色体异常率、NV和ICV均呈增加趋势。处理洋葱根尖细胞的有丝分裂指数和染色体异常与对照有显著差异。有丝分裂指数与染色体异常呈反比关系。几乎所有处理过的洋葱根尖细胞都表现出抑制线粒体分裂的作用。由此推测，洋葱根尖细胞有丝分裂抑制和染色体异常可能与洋葱根尖细胞中β- n -草酰- l- α， β-二氨基丙酸(Lathyrogens)有关。j . Bio-Sci。31(1): 51- 60,2023
{"title":"Cytological Effects of Two Varieties of Lathyrus Sativus L. Extracts on Onion Root Tip Cells","authors":"Md Saifur Rahman Rahman, Ummay Salma Pritha, Md Mamunur Rashid Sarkar Sarkar, Golam Kabir Kabir","doi":"10.3329/jbs.v31i1.69534","DOIUrl":"https://doi.org/10.3329/jbs.v31i1.69534","url":null,"abstract":"Lathyrus sativus L. causes lathyrism both in animals and human due to the presence of the neurotoxin β-ODAP (β -N-Oxalyl-L-α, β -diaminopropionic acid). This study was performed to find out the toxic effect of grass pea on onion root tip cells. The root lengths of onion were reduced as the concentrations of different plant parts extracts of grass pea increased. The percentages of chromosomal abnormalities, NV and ICV of onion root tip cells showed an increasing trend with the increasing of different extracts concentrations. The mitotic index and chromosomal abnormalities in treated onion root tip cells were significantly different than that of control. The mitotic index and chromosomal abnormalities had a reverse relationship. Almost all the treated root tip cells of onion showed this mito-depressive effect. From this findings, it may concluded that β -N-Oxayl-L- α, β-diaminopropionic acid (Lathyrogens) in Lathyrus sativus may be responsible for mitotic depression and chromosomal abnormalities on the root tip cells of onion. J. Bio-Sci. 31(1): 51-60, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":"136 33","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135725179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mst Rima Aktar Aktar, Dil Afroza Khanom Khanom, Md Delwer Hossain Hossain
An experiment was conducted to assess the effect of stocking density on growth, survival and production performance of Clarias batrachus (Magur) fry using nursery hapa in experimental pond of Dept. of Fisheries, University of Rajshahi. The research was carried out for a period of three months from May to July, 2021 consisting of four treatments each with two replications. A total of eight hapa were prepared using net each having an area of 1.2 × 0.9 × 0.9 m3. Stocking density was maintained at the rate of 300, 350, 400 and 450 fry ∕ m3 in T1, T2, T3 and T4 respectively where the mean initial weight of hatchling was 0.04±0.01 g. Different physico-chemical parameter of water were monitored fortnightly where the mean value of water temperature, water transparency, dissolved oxygen, carbon dioxide, PH and NH3-N was observed 28.25±1.18°C, 26.12±0.18 cm, 8.44±0.45 mg/l, 1.78±0.03 mg/l, 6.88±0.04 and 0.007± 0.00 mg/l respectively. Except NH3-N no significant difference (p˃0.05) was found among the treatments and all the parameter were in suitable range for fry rearing. Highest mean final weight, weight gain, SGR (%/day), survival rate, along with lower FCR was found in T1 which was 8.00±0.13 g, 7.96±0.07 g, 5.65±0.00 (%/day) and 91±0.70 (%) respectively followed by T2, T3 and T4 where significant variation (p˂0.05) was found among them. Maximum net yield (kg/m3/90 days) was 2.51±0.07 which was obtained from T3 followed by 2.48±0.02, 2.37±0.02 and 2.20±0.05 in T4, T2 and T1. On the other hand, benefit cost ratio (BCR) was found significantly higher (p˂0.05) in T1 (0.73±0.01) than T2 (0.66 ±0.01), T3 (0.56±0.00) and T4 (0.43±0.02). The overall result indicated that a stocking density of 300 fry/m3 (T1) could be more profitable for Clarias batrachus fry rearing in nursery hapa. J. Bio-Sci. 31(1): 17-27, 2023
{"title":"Effect of Stocking Density on Growth, Survival and Production Performances of Clarias Batrachus Fry in Nursery Hapa Under Semi-intensive Culture System of Rajshahi University Campus, Bangladesh","authors":"Mst Rima Aktar Aktar, Dil Afroza Khanom Khanom, Md Delwer Hossain Hossain","doi":"10.3329/jbs.v31i1.69531","DOIUrl":"https://doi.org/10.3329/jbs.v31i1.69531","url":null,"abstract":"An experiment was conducted to assess the effect of stocking density on growth, survival and production performance of Clarias batrachus (Magur) fry using nursery hapa in experimental pond of Dept. of Fisheries, University of Rajshahi. The research was carried out for a period of three months from May to July, 2021 consisting of four treatments each with two replications. A total of eight hapa were prepared using net each having an area of 1.2 × 0.9 × 0.9 m3. Stocking density was maintained at the rate of 300, 350, 400 and 450 fry ∕ m3 in T1, T2, T3 and T4 respectively where the mean initial weight of hatchling was 0.04±0.01 g. Different physico-chemical parameter of water were monitored fortnightly where the mean value of water temperature, water transparency, dissolved oxygen, carbon dioxide, PH and NH3-N was observed 28.25±1.18°C, 26.12±0.18 cm, 8.44±0.45 mg/l, 1.78±0.03 mg/l, 6.88±0.04 and 0.007± 0.00 mg/l respectively. Except NH3-N no significant difference (p˃0.05) was found among the treatments and all the parameter were in suitable range for fry rearing. Highest mean final weight, weight gain, SGR (%/day), survival rate, along with lower FCR was found in T1 which was 8.00±0.13 g, 7.96±0.07 g, 5.65±0.00 (%/day) and 91±0.70 (%) respectively followed by T2, T3 and T4 where significant variation (p˂0.05) was found among them. Maximum net yield (kg/m3/90 days) was 2.51±0.07 which was obtained from T3 followed by 2.48±0.02, 2.37±0.02 and 2.20±0.05 in T4, T2 and T1. On the other hand, benefit cost ratio (BCR) was found significantly higher (p˂0.05) in T1 (0.73±0.01) than T2 (0.66 ±0.01), T3 (0.56±0.00) and T4 (0.43±0.02). The overall result indicated that a stocking density of 300 fry/m3 (T1) could be more profitable for Clarias batrachus fry rearing in nursery hapa. J. Bio-Sci. 31(1): 17-27, 2023","PeriodicalId":90580,"journal":{"name":"Journal of bio-science","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135724750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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