首页 > 最新文献

BLDE University Journal of Health Sciences最新文献

英文 中文
Effect of transcranial direct current stimulation on puzzle-solving ability in stroke patients with cognitive dysfunction: A pilot study 经颅直流电刺激对脑卒中认知功能障碍患者解谜能力影响的初步研究
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_178_22
Saniya Sumant, Surinder Kumar
PURPOSE: Stroke lies among the most disabling diseases and is world-wide a leading cause of death. Most of the stroke patients experience cognitive deficits associated with executive dysfunction (decision making, problem solving, working memory, and cognitive flexibility). Executive dysfunction in stroke makes the patients vulnerable to depression, anxiety as their daily activities like personal, social, cultural and occupational are severely affected. Thus, the dependency increases and their quality of life decreases. Problem solving is one such important executive function required in day-to-day life. Puzzle solving reflects onto ones problem-solving ability that requires understanding, conceptual knowledge recruitment, novel and insightful thinking, and processing a solution. The purpose of this study was to determine if noninvasive brain stimulation has any effect on puzzle-solving ability of stroke patients and to assess their performance on the same. METHOD: A 3-week interventional study on 11 stroke participants was done. The samples were assessed at baseline for cognitive impairment using Montreal Cognitive Assessment Scale. Participants with scores <26 were given a 30-piece Jigsaw Puzzle to solve and Wisconsin Card Sorting Test (WCST) was done, both at baseline and after 3 weeks. RESULTS: This study confirmed that there was improvement in the performance of solving the Jigsaw Puzzle after application of transcranial direct current stimulation (TDCS) (P = 0.005), but the scores on WCST showed no significant reliable change (P = 0.192). CONCLUSION: This study concluded that TDCS is effective in improving puzzle-solving ability in stroke patients.
目的:中风是最致残的疾病之一,是世界范围内死亡的主要原因。大多数中风患者经历与执行功能障碍(决策、解决问题、工作记忆和认知灵活性)相关的认知缺陷。脑卒中执行功能障碍使患者的个人、社会、文化、职业等日常活动受到严重影响,容易产生抑郁、焦虑等情绪。因此,依赖性增加,生活质量下降。解决问题是日常生活中需要的一种重要的执行功能。解谜反映了一个人解决问题的能力,需要理解,概念性知识的吸收,新颖和深刻的思维,并处理一个解决方案。本研究的目的是确定非侵入性脑刺激是否对脑卒中患者的解谜能力有任何影响,并评估他们在此方面的表现。方法:对11名中风患者进行为期3周的介入研究。使用蒙特利尔认知评估量表对样本进行基线认知障碍评估。得分<26的参与者在基线和3周后分别进行了30块拼图和威斯康星卡片分类测试(WCST)。结果:本研究证实经颅直流电刺激(TDCS)对拼图游戏的解决有改善作用(P = 0.005),但WCST得分无显著可靠变化(P = 0.192)。结论:TDCS可有效提高脑卒中患者的解谜能力。
{"title":"Effect of transcranial direct current stimulation on puzzle-solving ability in stroke patients with cognitive dysfunction: A pilot study","authors":"Saniya Sumant, Surinder Kumar","doi":"10.4103/bjhs.bjhs_178_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_178_22","url":null,"abstract":"PURPOSE: Stroke lies among the most disabling diseases and is world-wide a leading cause of death. Most of the stroke patients experience cognitive deficits associated with executive dysfunction (decision making, problem solving, working memory, and cognitive flexibility). Executive dysfunction in stroke makes the patients vulnerable to depression, anxiety as their daily activities like personal, social, cultural and occupational are severely affected. Thus, the dependency increases and their quality of life decreases. Problem solving is one such important executive function required in day-to-day life. Puzzle solving reflects onto ones problem-solving ability that requires understanding, conceptual knowledge recruitment, novel and insightful thinking, and processing a solution. The purpose of this study was to determine if noninvasive brain stimulation has any effect on puzzle-solving ability of stroke patients and to assess their performance on the same. METHOD: A 3-week interventional study on 11 stroke participants was done. The samples were assessed at baseline for cognitive impairment using Montreal Cognitive Assessment Scale. Participants with scores <26 were given a 30-piece Jigsaw Puzzle to solve and Wisconsin Card Sorting Test (WCST) was done, both at baseline and after 3 weeks. RESULTS: This study confirmed that there was improvement in the performance of solving the Jigsaw Puzzle after application of transcranial direct current stimulation (TDCS) (P = 0.005), but the scores on WCST showed no significant reliable change (P = 0.192). CONCLUSION: This study concluded that TDCS is effective in improving puzzle-solving ability in stroke patients.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"26 1","pages":"150 - 154"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84061115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An assessment of the effectiveness and perception of the doodle – Video reinforced teaching method 评价涂鸦-视频强化教学方法的有效性和观感
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_207_22
Anita Teli, Sheetal Harkuni, Deepti M. Kadeangadi, Madhumati J Patil
{"title":"An assessment of the effectiveness and perception of the doodle – Video reinforced teaching method","authors":"Anita Teli, Sheetal Harkuni, Deepti M. Kadeangadi, Madhumati J Patil","doi":"10.4103/bjhs.bjhs_207_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_207_22","url":null,"abstract":"","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89360283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of noncommunicable diseases and their risk factors among the population residing in the villages under a subcenter in Hassan: A community-based cross-sectional study 哈桑某分中心下辖村庄居民非传染性疾病患病率及其危险因素:基于社区的横断面研究
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_1_23
PriankaShashi Kumar, GM Venkatesh, Anjan Sreeranga
{"title":"Prevalence of noncommunicable diseases and their risk factors among the population residing in the villages under a subcenter in Hassan: A community-based cross-sectional study","authors":"PriankaShashi Kumar, GM Venkatesh, Anjan Sreeranga","doi":"10.4103/bjhs.bjhs_1_23","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_1_23","url":null,"abstract":"","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75199690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological study on nonsyndromic hearing impairment: North Karnataka, India 印度北卡纳塔克邦非综合征性听力障碍的流行病学研究
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_124_22
Smita Hegde, Rajat Hegde, S. Kulkarni, Mohd. Shannawaz, Kusal K. Das, P. Gai, R. Bulagouda
BACKGROUND: In India, hearing loss is a major but often ignored problem. Sixty-three million individuals (6.3%) in India have severe hearing loss. OBJECTIVE: The present study is the first to examine epidemiological factors that are pertinent to children from North Karnataka, India, who have nonsyndromic hearing loss. MATERIALS AND METHODS: This study was conducted by attending government and private ENT hospitals and special schools for deaf children in North Karnataka. A total of 638 children with hearing loss of age ranging from 1 to 18 years were screened. Two hundred and seventy out of 638 were excluded from the study because of other anomalies and some were not ready to participate in the study. A semistructured interview was followed for data collection. All the required personal demographic details and medical details of ear examination of inspection history, otoscopy, tympanometry, and pure-tone audiometry were noted. Age, gender, hearing loss type severity, family history, and consanguinity were considered epidemiological factors in the study. RESULTS: Statistical analysis showed that there was no significant association of age difference between the two genders, but the majority of male children were deaf compared to female children (63.9% vs. 36.1%). Prelingual hearing loss was observed in 94.6% and postlingual hearing loss was in 5.4%. 93.5% of children had bilateral deafness and only 6.5% had unilateral deafness. In the present study population, 3.5% of children had mild, 7.3% had moderate, 2.7% had severe, and 86.4% had profound hearing loss. 83.2% of the children had a family history of deafness. There was no significant association of consanguinity to deafness in our study group (P = 0.07). CONCLUSION: The prevalence of hearing loss was high in the North Karnataka population. We observed the following in our research group: gender, poor education or lack of awareness of pregnancy, and lack of knowledge of consanguinity. so, People need to Know more about these disorders and this is only possible by the Research or education.
背景:在印度,听力损失是一个主要但经常被忽视的问题。印度有6300万人(6.3%)患有严重听力损失。目的:本研究首次研究了与印度北卡纳塔克邦非综合征性听力损失儿童相关的流行病学因素。材料和方法:本研究是在北卡纳塔克邦的公立和私立耳鼻喉医院以及聋哑儿童特殊学校进行的。共有638名1至18岁的听力损失儿童接受了筛查。638人中有270人因其他异常而被排除在研究之外,有些人还没有准备好参加研究。采用半结构化访谈进行数据收集。记录了所有需要的个人人口统计信息和耳部检查的医疗信息,包括检查史、耳镜检查、鼓室测量和纯音听力测量。年龄、性别、听力损失类型严重程度、家族史和亲属关系被认为是研究中的流行病学因素。结果:统计分析显示,两种性别的年龄差异无显著相关性,但男性儿童的失聪发生率高于女性儿童(63.9%比36.1%)。语前听力损失占94.6%,语后听力损失占5.4%。93.5%患儿为双侧耳聋,6.5%患儿为单侧耳聋。在本研究人群中,3.5%的儿童为轻度听力损失,7.3%为中度听力损失,2.7%为重度听力损失,86.4%为重度听力损失。83.2%的儿童有耳聋家族史。在我们的研究组中,亲缘关系与耳聋无显著相关性(P = 0.07)。结论:卡纳塔克邦北部人群听力损失发生率较高。在我们的研究组中,我们观察到:性别,教育程度低或缺乏怀孕意识,以及缺乏血缘知识。所以,人们需要更多地了解这些疾病,这只能通过研究或教育来实现。
{"title":"Epidemiological study on nonsyndromic hearing impairment: North Karnataka, India","authors":"Smita Hegde, Rajat Hegde, S. Kulkarni, Mohd. Shannawaz, Kusal K. Das, P. Gai, R. Bulagouda","doi":"10.4103/bjhs.bjhs_124_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_124_22","url":null,"abstract":"BACKGROUND: In India, hearing loss is a major but often ignored problem. Sixty-three million individuals (6.3%) in India have severe hearing loss. OBJECTIVE: The present study is the first to examine epidemiological factors that are pertinent to children from North Karnataka, India, who have nonsyndromic hearing loss. MATERIALS AND METHODS: This study was conducted by attending government and private ENT hospitals and special schools for deaf children in North Karnataka. A total of 638 children with hearing loss of age ranging from 1 to 18 years were screened. Two hundred and seventy out of 638 were excluded from the study because of other anomalies and some were not ready to participate in the study. A semistructured interview was followed for data collection. All the required personal demographic details and medical details of ear examination of inspection history, otoscopy, tympanometry, and pure-tone audiometry were noted. Age, gender, hearing loss type severity, family history, and consanguinity were considered epidemiological factors in the study. RESULTS: Statistical analysis showed that there was no significant association of age difference between the two genders, but the majority of male children were deaf compared to female children (63.9% vs. 36.1%). Prelingual hearing loss was observed in 94.6% and postlingual hearing loss was in 5.4%. 93.5% of children had bilateral deafness and only 6.5% had unilateral deafness. In the present study population, 3.5% of children had mild, 7.3% had moderate, 2.7% had severe, and 86.4% had profound hearing loss. 83.2% of the children had a family history of deafness. There was no significant association of consanguinity to deafness in our study group (P = 0.07). CONCLUSION: The prevalence of hearing loss was high in the North Karnataka population. We observed the following in our research group: gender, poor education or lack of awareness of pregnancy, and lack of knowledge of consanguinity. so, People need to Know more about these disorders and this is only possible by the Research or education.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"31 1","pages":"124 - 129"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74537516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of knowledge, attitude, and practices in patients with Diabetes mellitus in a tertiary care hospital 三级医院糖尿病患者的知识、态度和行为评估
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_141_22
Sanatkumar B Nyamagoud, AgadiHiremath Viswanatha Swamy, Bharati Kangrali
{"title":"Assessment of knowledge, attitude, and practices in patients with Diabetes mellitus in a tertiary care hospital","authors":"Sanatkumar B Nyamagoud, AgadiHiremath Viswanatha Swamy, Bharati Kangrali","doi":"10.4103/bjhs.bjhs_141_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_141_22","url":null,"abstract":"","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78988176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviewing placental volumetry and thickness and its correlation with adverse feto maternal outcome - A cross sectional study in Western India 回顾胎盘体积和厚度及其与不良胎母结局的关系-西印度的横断面研究
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_86_22
S. Gaikwad, Avinash P. Dubbewar, R. Hiremath, S. Rai, Prathyusha Gouru
BACKGROUND: Placenta performs several functions including respiration, nutrition, and excretion for the fetus when playing a central role in regulating metabolic, endocrinological, and immunological functions during pregnancy. OBJECTIVE: To analyze the putative correlation of placental parameters including volume and thickness with adverse maternofetal outcomes. METHODOLOGY: A longitudinal observational study was undertaken for 2 years. The sample size was calculated, which was 140. Data were collected, and fetomaternal outcomes of gestational diabetes mellitus (GDM), gestational hypertension (HTN), preeclampsia, and intrauterine growth retardation (IUGR) were derived. A correlation was studied between placental volume (PV) and placental thickness (PT) with fetomaternal outcomes. RESULTS: Approximately half (42.85%) of the study population were primigravida, with overall mean age being 22.67 ± 2.94 years. 46 subjects had adverse fetomaternal outcomes in the form of gestational HTN, preeclampsia, GDM, and IUGR. The most frequent adverse outcome noted was IUGR in 19 cases (41.29%). Among the study population, 90% were term deliveries and 10% were preterm. Spontaneous vertex delivery was seen in 74.29% of the cases. 24.29% of the cases underwent lower segment cesarean section and 1.43% underwent vacuum-assisted delivery. The PV and PT (mm) were compared in healthy subjects with HTN, GDM, and IUGR pregnancies in all three trimesters. A strong correlation (R = 0.96, 95% confidence interval = 0.95–0.98) between birth weight with placental weight was noted. The difference between the means of PV during the first, second, and third trimester and hypertensive disorders in pregnancy was not statistically significant; among GDM and non-GDM patients, was statistically significant in the first and second trimester; and among IUGR and non-IUGR patients, was seen during the third trimester. Similarly, the difference between the means of PT in all trimesters and hypertensive disorders in pregnancy was not statistically significant; among GDM and non-GDM patients, a statistically significant association was seen during the second trimester; and among IUGR and non-IUGR patients, a statistically significant association was seen during the third trimester. CONCLUSIONS: PV in the 1st, 2nd, and 3rd trimesters is significantly less in patients with HTN and IUGR. PV is a predictor of adverse fetomaternal outcomes. Hypertensive subjects had thin placenta with low PV. Hypertensive subjects had thin placenta with low PV. IUGR subjects had thin placenta with low PV. Diabetic subjects had thick placenta. PT is also a predictor of adverse fetomaternal outcomes. Placental weight is known to correlate with fetal weight at term.
背景:胎盘在调节妊娠期的代谢、内分泌和免疫功能时,为胎儿发挥呼吸、营养和排泄等多种功能。目的:分析胎盘体积、厚度等参数与母胎不良结局的相关性。方法:进行了为期2年的纵向观察研究。计算样本量,为140例。收集数据,得出妊娠期糖尿病(GDM)、妊娠期高血压(HTN)、先兆子痫和宫内生长迟缓(IUGR)的产儿结局。研究了胎盘体积(PV)和胎盘厚度(PT)与胎儿结局的相关性。结果:大约一半(42.85%)的研究人群为原始人,总体平均年龄为22.67±2.94岁。46名受试者出现妊娠期HTN、先兆子痫、GDM和IUGR等不良结局。最常见的不良反应是IUGR, 19例(41.29%)。在研究人群中,90%是足月分娩,10%是早产。自发性顶点分娩占74.29%。下段剖宫产占24.29%,真空辅助分娩占1.43%。比较HTN、GDM和IUGR妊娠的健康受试者在所有三个月的PV和PT (mm)。出生体重与胎盘体重之间有很强的相关性(R = 0.96, 95%可信区间= 0.95-0.98)。妊娠前、中、晚期PV均值与妊娠期高血压疾病的差异无统计学意义;在妊娠早期和中期,GDM和非GDM患者中,差异有统计学意义;在IUGR和非IUGR患者中,在妊娠晚期出现。同样,所有妊娠期PT均值与妊娠期高血压疾病的差异无统计学意义;在GDM和非GDM患者中,在妊娠中期发现有统计学意义的相关性;在IUGR和非IUGR患者中,在妊娠晚期观察到统计学上显著的关联。结论:HTN和IUGR患者妊娠1、2、3个月的PV显著减少。PV是不良胎儿结局的预测因子。高血压患者胎盘薄,PV低。高血压患者胎盘薄,PV低。IUGR患者胎盘薄,PV低。糖尿病患者胎盘较厚。PT也是不良胎儿结局的预测因子。已知胎盘重量与胎儿足月体重相关。
{"title":"Reviewing placental volumetry and thickness and its correlation with adverse feto maternal outcome - A cross sectional study in Western India","authors":"S. Gaikwad, Avinash P. Dubbewar, R. Hiremath, S. Rai, Prathyusha Gouru","doi":"10.4103/bjhs.bjhs_86_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_86_22","url":null,"abstract":"BACKGROUND: Placenta performs several functions including respiration, nutrition, and excretion for the fetus when playing a central role in regulating metabolic, endocrinological, and immunological functions during pregnancy. OBJECTIVE: To analyze the putative correlation of placental parameters including volume and thickness with adverse maternofetal outcomes. METHODOLOGY: A longitudinal observational study was undertaken for 2 years. The sample size was calculated, which was 140. Data were collected, and fetomaternal outcomes of gestational diabetes mellitus (GDM), gestational hypertension (HTN), preeclampsia, and intrauterine growth retardation (IUGR) were derived. A correlation was studied between placental volume (PV) and placental thickness (PT) with fetomaternal outcomes. RESULTS: Approximately half (42.85%) of the study population were primigravida, with overall mean age being 22.67 ± 2.94 years. 46 subjects had adverse fetomaternal outcomes in the form of gestational HTN, preeclampsia, GDM, and IUGR. The most frequent adverse outcome noted was IUGR in 19 cases (41.29%). Among the study population, 90% were term deliveries and 10% were preterm. Spontaneous vertex delivery was seen in 74.29% of the cases. 24.29% of the cases underwent lower segment cesarean section and 1.43% underwent vacuum-assisted delivery. The PV and PT (mm) were compared in healthy subjects with HTN, GDM, and IUGR pregnancies in all three trimesters. A strong correlation (R = 0.96, 95% confidence interval = 0.95–0.98) between birth weight with placental weight was noted. The difference between the means of PV during the first, second, and third trimester and hypertensive disorders in pregnancy was not statistically significant; among GDM and non-GDM patients, was statistically significant in the first and second trimester; and among IUGR and non-IUGR patients, was seen during the third trimester. Similarly, the difference between the means of PT in all trimesters and hypertensive disorders in pregnancy was not statistically significant; among GDM and non-GDM patients, a statistically significant association was seen during the second trimester; and among IUGR and non-IUGR patients, a statistically significant association was seen during the third trimester. CONCLUSIONS: PV in the 1st, 2nd, and 3rd trimesters is significantly less in patients with HTN and IUGR. PV is a predictor of adverse fetomaternal outcomes. Hypertensive subjects had thin placenta with low PV. Hypertensive subjects had thin placenta with low PV. IUGR subjects had thin placenta with low PV. Diabetic subjects had thick placenta. PT is also a predictor of adverse fetomaternal outcomes. Placental weight is known to correlate with fetal weight at term.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"40 7","pages":"78 - 84"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72477332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of methylenetetrahydrofolate reductase polymorphism and male infertility in type 2 diabetes mellitus patients 亚甲基四氢叶酸还原酶多态性与2型糖尿病患者男性不育的关系
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_167_22
K. Babu, Manibalan Vijayaraman, Deepti Shastri, E. Manivannan
INTRODUCTION: As per World Health Organization, Infertility is a condition which is characterized by not getting conceived with more than 1-year of unprotected sexual intercourse without usage of any contraceptive aids. Folate has a significant role in the metabolism of the cells, like nucleic acids synthesis, gene expression by means of remethylation of the homocysteine into methionine. In the males, deficiency of folate leads to reduced proliferation of the sperm cells. Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase genes result in alterations of the methylations resulting pathological conditions being a potential risk factor for male infertility. MATERIALS AND METHODS: A total of 100 diabetic infertile males were selected as the study group and 100 nondiabetic fertile males were included as the control group. Blood samples were analyzed for the MTHFR polymorphisms. DNA extraction was done and the extract is subjected to polymerase chain reaction amplification. The resultant is subjected to electrophoresis for MTHFR gene allele confirmation. Statistical analysis was done using IBM SPSS Statistics 20 package. Chi-square test, odds ratio has been done and P < 0.05 is considered statistically significant. RESULTS: Genotype frequencies of MTHFR C677T, A1298C in all the subjects were analyzed for the Hardy–Weinberg law of genetic equilibrium. Mutant polymorphisms of MTHFR C677T, i.e., thymine-thymine and cytosine-thymine were increased significantly. Similarly, MTHFR A1298C mutant polymorphisms, i.e. adenine-cytosine, cytosine-cytosine were increased significantly in the infertile group than in the fertile group. DISCUSSION: Mutations of both MTHFR C677T, A1298C are found to be linked with lowered enzyme activity. We found that the occurrence of mutant homozygous and mutant heterozygous genotypes was increased in a diabetic male infertile group when compared to nondiabetic fertile group. Hence, it can be concluded that presence of single-nucleotide polymorphisms of MTHFR will increase the risk of infertility in diabetic male population.
导言:根据世界卫生组织的定义,不孕症是指在没有使用任何避孕手段的情况下进行无保护的性交超过1年而未怀孕的一种情况。叶酸在细胞代谢中具有重要作用,如核酸合成、同型半胱氨酸再甲基化为蛋氨酸的基因表达等。在男性中,叶酸缺乏会导致精子细胞的增殖减少。亚甲基四氢叶酸还原酶(MTHFR)和蛋氨酸合成酶还原酶基因的多态性导致甲基化的改变,从而导致病理状况,这是男性不育的潜在危险因素。材料与方法:选取100例男性糖尿病不育患者作为研究组,100例男性非糖尿病不育患者作为对照组。对血液样本进行MTHFR多态性分析。提取DNA并进行聚合酶链反应扩增。结果进行MTHFR基因等位基因的电泳确认。采用IBM SPSS Statistics 20软件包进行统计分析。卡方检验,做优势比,P < 0.05认为差异有统计学意义。结果:分析所有受试者MTHFR C677T、A1298C基因型频率符合Hardy-Weinberg遗传平衡定律。MTHFR C677T突变多态性,即胸腺嘧啶-胸腺嘧啶和胞嘧啶-胸腺嘧啶显著增加。同样,MTHFR A1298C突变体多态性,即腺嘌呤-胞嘧啶、胞嘧啶-胞嘧啶在不育组明显高于可育组。讨论:发现MTHFR C677T、A1298C突变与酶活性降低有关。我们发现,与非糖尿病男性不育组相比,糖尿病男性不育组突变型纯合子和突变型杂合子的发生率增加。因此,可以得出结论,MTHFR单核苷酸多态性的存在会增加男性糖尿病人群的不育风险。
{"title":"Association of methylenetetrahydrofolate reductase polymorphism and male infertility in type 2 diabetes mellitus patients","authors":"K. Babu, Manibalan Vijayaraman, Deepti Shastri, E. Manivannan","doi":"10.4103/bjhs.bjhs_167_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_167_22","url":null,"abstract":"INTRODUCTION: As per World Health Organization, Infertility is a condition which is characterized by not getting conceived with more than 1-year of unprotected sexual intercourse without usage of any contraceptive aids. Folate has a significant role in the metabolism of the cells, like nucleic acids synthesis, gene expression by means of remethylation of the homocysteine into methionine. In the males, deficiency of folate leads to reduced proliferation of the sperm cells. Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase genes result in alterations of the methylations resulting pathological conditions being a potential risk factor for male infertility. MATERIALS AND METHODS: A total of 100 diabetic infertile males were selected as the study group and 100 nondiabetic fertile males were included as the control group. Blood samples were analyzed for the MTHFR polymorphisms. DNA extraction was done and the extract is subjected to polymerase chain reaction amplification. The resultant is subjected to electrophoresis for MTHFR gene allele confirmation. Statistical analysis was done using IBM SPSS Statistics 20 package. Chi-square test, odds ratio has been done and P < 0.05 is considered statistically significant. RESULTS: Genotype frequencies of MTHFR C677T, A1298C in all the subjects were analyzed for the Hardy–Weinberg law of genetic equilibrium. Mutant polymorphisms of MTHFR C677T, i.e., thymine-thymine and cytosine-thymine were increased significantly. Similarly, MTHFR A1298C mutant polymorphisms, i.e. adenine-cytosine, cytosine-cytosine were increased significantly in the infertile group than in the fertile group. DISCUSSION: Mutations of both MTHFR C677T, A1298C are found to be linked with lowered enzyme activity. We found that the occurrence of mutant homozygous and mutant heterozygous genotypes was increased in a diabetic male infertile group when compared to nondiabetic fertile group. Hence, it can be concluded that presence of single-nucleotide polymorphisms of MTHFR will increase the risk of infertility in diabetic male population.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"17 1","pages":"51 - 55"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75090256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive effect of Ayurvedic drugs in normalization of hematological parameters in acquired aplastic anemia 阿育吠陀药物对获得性再生障碍性贫血血液学指标正常化的积极作用
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_138_22
Anshul, Alok Srivastava
In pancytopenia due to aplastic anemia (AA), bone marrow hypocellularity leads to hazardous failure of hematopoiesis. Āyurveda treatment was given to a 30-year-old male patient known case of severe acquired AA, considering it under Pāṇḍūroga (~anemia). A study was carried out to search the effectiveness of Āyurveda medications, especially Rasāyana (~immunomodulator) mentioned in the treatment of Pāṇḍū in the management of AA. The patient was administered Rasāyana drugs, such as Śilājatukalpa, Amṛītā-Satta, Punarnavā, and Maṇḍūr having hepatoprotective, anxiolytic, and antioxidant properties, and ĀrogyavardhanīVaṭī, TrikaṭūCūrṇa. Hematological investigations of the patient were carried out every 2 months for 2 and ½ years. Erythrocyte sedimentation rate, white blood cell, and red cell distribution width coefficient of variation were in the normal range after treatment. Red blood cells, HB, and platelets were found to be increased, which were not growing before treatment. Liver function test, kidney function test, serum sodium, and potassium were normal during treatment. Complete relief in symptoms was found. The present study concludes that the severity of pancytopenia due to AA can be managed effectively with Ayurvedic medications.
在再生障碍性贫血(AA)引起的全血细胞减少症中,骨髓细胞减少会导致危险的造血功能衰竭。对已知严重获得性AA的30岁男性患者进行Āyurveda治疗,考虑其在Pāṇḍūroga(~贫血)项下。本研究旨在探讨Āyurveda药物,特别是Rasāyana(~免疫调节剂)治疗Pāṇḍū在AA治疗中的有效性。患者服用Rasāyana药物,如Śilājatukalpa、Amṛītā-Satta、punarnavha和Maṇḍūr,这些药物具有保肝、抗焦虑和抗氧化作用,以及ĀrogyavardhanīVaṭī、TrikaṭūCūrṇa。患者每2个月进行一次血液学检查,持续2年半。治疗后红细胞沉降率、白细胞、红细胞分布宽度变异系数均在正常范围内。血红细胞、血红蛋白和血小板增加,而这些在治疗前是没有增长的。治疗期间肝功能、肾功能、血清钠、钾均正常。症状完全缓解。目前的研究表明,阿育吠陀药物可以有效地控制AA引起的全血细胞减少症的严重程度。
{"title":"Positive effect of Ayurvedic drugs in normalization of hematological parameters in acquired aplastic anemia","authors":"Anshul, Alok Srivastava","doi":"10.4103/bjhs.bjhs_138_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_138_22","url":null,"abstract":"In pancytopenia due to aplastic anemia (AA), bone marrow hypocellularity leads to hazardous failure of hematopoiesis. Āyurveda treatment was given to a 30-year-old male patient known case of severe acquired AA, considering it under Pāṇḍūroga (~anemia). A study was carried out to search the effectiveness of Āyurveda medications, especially Rasāyana (~immunomodulator) mentioned in the treatment of Pāṇḍū in the management of AA. The patient was administered Rasāyana drugs, such as Śilājatukalpa, Amṛītā-Satta, Punarnavā, and Maṇḍūr having hepatoprotective, anxiolytic, and antioxidant properties, and ĀrogyavardhanīVaṭī, TrikaṭūCūrṇa. Hematological investigations of the patient were carried out every 2 months for 2 and ½ years. Erythrocyte sedimentation rate, white blood cell, and red cell distribution width coefficient of variation were in the normal range after treatment. Red blood cells, HB, and platelets were found to be increased, which were not growing before treatment. Liver function test, kidney function test, serum sodium, and potassium were normal during treatment. Complete relief in symptoms was found. The present study concludes that the severity of pancytopenia due to AA can be managed effectively with Ayurvedic medications.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"1 1","pages":"175 - 178"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80212807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leech therapy and adjuvant Ayurveda treatment in the management of diabetic foot ulcer with atherosclerosis 水蛭疗法和辅助阿育吠陀治疗糖尿病足溃疡合并动脉粥样硬化的疗效观察
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_135_22
Snehal Sonani, T. Dudhamal
Diabetic patients are more prevalent to atherosclerosis (29.1%); however, its pathophysiology is still unclear. Such cases mostly convert into either amputation due to rapid spread or lifelong anticoagulant. Ayurveda is famed to be a tool in prevention and management of such fatal or disabling surgeries by parasurgical procedure, i.e., leech therapy, Agnikarma, etc. This study presents a case of postdiabetic atherosclerosis (male/54 years old) with a complaint of blackening of the great toe of the right lower limb and and other associated symptoms such as intermittent claudication (Garde 4), Burning in sole, occasional numbness in the foot. this case was managed by the Ayurveda para-surgical procedure (Leech therapy). The patient was a known case of DM and taking medication for it for the last 1 year, but his blood sugar level was found to be uncontrolled (HB1Ac: 9.90). The patient had surgical history of coronary artery bypass graft before 8 years. His bilateral lower limb computed tomography angiography was suggestive of diffuse atherosclerotic fibrocalcified wall plaques in abdominal aorta, iliac, femoral, and both leg arteries. Clinical examination revealed black right greater toe with line of demarcation and on palpation, feeble femoral artery and downstream non-palpable arteries. As a part of treatment, leech application along with some rejuvenating oral drugs i.e. Sanjvani vati and pippali churna was given to the patient. On 2nd week of treatment protocol, black gangrenous great- toe was amputed which afterwards become open wound(approx.2cm x 2 cm). Afterward, daily wound dressing was done with Apamarga kshar taila or Thumari taila (As per the status of the wound) after cleaning with Triphala Kwath. After completion of treatment protocol, the patient got 85-90% relief in clinical symptoms and also previously feeble arteries were felt with full volume.
糖尿病患者动脉粥样硬化发生率更高(29.1%);然而,其病理生理机制尚不清楚。这些病例大多因迅速扩散而截肢或终身抗凝。阿育吠陀是著名的工具,在预防和管理这种致命或致残手术的辅助外科手术,即水蛭疗法,Agnikarma等。本研究报告一例糖尿病后动脉粥样硬化患者(男性/54岁),主诉右下肢大脚趾发黑,并伴有间歇性跛行(第4区)、足底灼烧、偶有足部麻木等相关症状。本病例采用阿育吠陀辅助手术治疗(水蛭疗法)。该患者为已知的糖尿病病例,并已服药1年,但血糖水平未控制(HB1Ac: 9.90)。患者8年前有冠状动脉搭桥术手术史。他的双侧下肢计算机断层血管造影提示腹主动脉、髂动脉、股动脉和两条腿动脉弥漫性动脉粥样硬化纤维钙化壁斑块。临床检查显示右大趾黑色,有分界线,触诊,股动脉无力,下游动脉未触及。作为治疗的一部分,水蛭应用以及一些恢复活力的口服药物,即Sanjvani vati和pippali churna给予患者。治疗方案第2周,切除黑色坏疽性大脚趾,后成为开放性创面(约1。2cm × 2cm)。之后,在用Triphala Kwath清洗后,每天用Apamarga kshar taila或Thumari taila(根据伤口状况)包扎伤口。治疗方案完成后,患者临床症状缓解85-90%,既往虚弱的动脉也感觉容积饱满。
{"title":"Leech therapy and adjuvant Ayurveda treatment in the management of diabetic foot ulcer with atherosclerosis","authors":"Snehal Sonani, T. Dudhamal","doi":"10.4103/bjhs.bjhs_135_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_135_22","url":null,"abstract":"Diabetic patients are more prevalent to atherosclerosis (29.1%); however, its pathophysiology is still unclear. Such cases mostly convert into either amputation due to rapid spread or lifelong anticoagulant. Ayurveda is famed to be a tool in prevention and management of such fatal or disabling surgeries by parasurgical procedure, i.e., leech therapy, Agnikarma, etc. This study presents a case of postdiabetic atherosclerosis (male/54 years old) with a complaint of blackening of the great toe of the right lower limb and and other associated symptoms such as intermittent claudication (Garde 4), Burning in sole, occasional numbness in the foot. this case was managed by the Ayurveda para-surgical procedure (Leech therapy). The patient was a known case of DM and taking medication for it for the last 1 year, but his blood sugar level was found to be uncontrolled (HB1Ac: 9.90). The patient had surgical history of coronary artery bypass graft before 8 years. His bilateral lower limb computed tomography angiography was suggestive of diffuse atherosclerotic fibrocalcified wall plaques in abdominal aorta, iliac, femoral, and both leg arteries. Clinical examination revealed black right greater toe with line of demarcation and on palpation, feeble femoral artery and downstream non-palpable arteries. As a part of treatment, leech application along with some rejuvenating oral drugs i.e. Sanjvani vati and pippali churna was given to the patient. On 2nd week of treatment protocol, black gangrenous great- toe was amputed which afterwards become open wound(approx.2cm x 2 cm). Afterward, daily wound dressing was done with Apamarga kshar taila or Thumari taila (As per the status of the wound) after cleaning with Triphala Kwath. After completion of treatment protocol, the patient got 85-90% relief in clinical symptoms and also previously feeble arteries were felt with full volume.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"59 1 1","pages":"192 - 196"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77759936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of dietary habits in menstrual disorders among adolescent girls in Navi Mumbai, Western Maharashtra 饮食习惯在西马哈拉施特拉邦新孟买少女月经紊乱中的作用
Pub Date : 2023-01-01 DOI: 10.4103/bjhs.bjhs_101_22
Vaishali Talekar, Maharaj Singh, Kalpana Kamble, D. Mane
BACKGROUND: India is a developing country where malnutrition is the most common problems; we are dealing with emerging problems of consumption of convenience food and street food. These foods are easily available, awesome taste, have some packages and advertisements which attracts the new generations and skipping meals starts. Adolescent girls are getting the problems of overweight, underweight, thyroid disorders, anemia, and other hematological disorders. Ultimate aim of this research is to find out an association about between dietary habits and menstrual disorders in adolescent girls. METHODOLOGY: An observational study was carried out in adolescent girls of MGM School, Navi Mumbai, India, from October 2021 to December 2021, to find out the relation between dietary pattern verses menstrual disorders among adolescent girls. Numerical pain scale, modified women's health questionnaire, and daily diary were used to collect data from 100 adolescent girls. Nonprobability purposive sampling technique was used to select adolescent girls. STATISTICAL ANALYSIS: Statistical analysis was done using SPSS 24.0 software. RESULTS: The average age of menarche was 12.9 ± 2.7 years. The study showed that girls experienced moderate menstrual pain (54%), severe menstrual pain (21%), and premenstrual symptoms in 36% of adolescence girls. More than 42% of participants were eating street food and many of the girls had habits of skipping the meals in the afternoon. It was found that there was a significant association between dietary habits and menstrual problems (P ≤ 0.0001). The correlation coefficient between dietary habits and menstrual disorders was identified as r = 0.7 with P < 0.05. CONCLUSION: The menstrual disorders were arising problems among girls of schools of Navi Mumbai. Daily intake of appropriate amount of protein, CHO, fat, vitamins, and minerals can help reduce menstrual problems facing by adolescent girls.
背景:印度是一个发展中国家,营养不良是最常见的问题;我们正在处理方便食品和街头食品消费的新问题。这些食物很容易买到,味道很好,有一些吸引新一代的包装和广告,开始不吃饭。青春期女孩正面临超重、体重不足、甲状腺疾病、贫血和其他血液系统疾病的问题。本研究的最终目的是找出青春期女孩的饮食习惯和月经紊乱之间的联系。方法:于2021年10月至2021年12月对印度孟买MGM学校的青春期女孩进行观察性研究,以了解青春期女孩饮食模式与月经紊乱之间的关系。采用数值疼痛量表、修改后的女性健康问卷和日常日记对100名青春期少女进行数据收集。采用非概率有目的抽样方法对少女进行抽样。统计学分析:采用SPSS 24.0软件进行统计学分析。结果:初潮平均年龄为12.9±2.7岁。研究表明,青春期女孩中有中度痛经(54%)、重度痛经(21%)和36%的经前症状。超过42%的参与者吃街头小吃,许多女孩有下午不吃饭的习惯。研究发现,饮食习惯与月经问题之间存在显著相关性(P≤0.0001)。饮食习惯与月经紊乱的相关系数r = 0.7, P < 0.05。结论:新孟买地区学校女生月经紊乱问题日益突出。每天摄入适量的蛋白质、CHO、脂肪、维生素和矿物质有助于减少青春期女孩面临的月经问题。
{"title":"Role of dietary habits in menstrual disorders among adolescent girls in Navi Mumbai, Western Maharashtra","authors":"Vaishali Talekar, Maharaj Singh, Kalpana Kamble, D. Mane","doi":"10.4103/bjhs.bjhs_101_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_101_22","url":null,"abstract":"BACKGROUND: India is a developing country where malnutrition is the most common problems; we are dealing with emerging problems of consumption of convenience food and street food. These foods are easily available, awesome taste, have some packages and advertisements which attracts the new generations and skipping meals starts. Adolescent girls are getting the problems of overweight, underweight, thyroid disorders, anemia, and other hematological disorders. Ultimate aim of this research is to find out an association about between dietary habits and menstrual disorders in adolescent girls. METHODOLOGY: An observational study was carried out in adolescent girls of MGM School, Navi Mumbai, India, from October 2021 to December 2021, to find out the relation between dietary pattern verses menstrual disorders among adolescent girls. Numerical pain scale, modified women's health questionnaire, and daily diary were used to collect data from 100 adolescent girls. Nonprobability purposive sampling technique was used to select adolescent girls. STATISTICAL ANALYSIS: Statistical analysis was done using SPSS 24.0 software. RESULTS: The average age of menarche was 12.9 ± 2.7 years. The study showed that girls experienced moderate menstrual pain (54%), severe menstrual pain (21%), and premenstrual symptoms in 36% of adolescence girls. More than 42% of participants were eating street food and many of the girls had habits of skipping the meals in the afternoon. It was found that there was a significant association between dietary habits and menstrual problems (P ≤ 0.0001). The correlation coefficient between dietary habits and menstrual disorders was identified as r = 0.7 with P < 0.05. CONCLUSION: The menstrual disorders were arising problems among girls of schools of Navi Mumbai. Daily intake of appropriate amount of protein, CHO, fat, vitamins, and minerals can help reduce menstrual problems facing by adolescent girls.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"10 1","pages":"100 - 105"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89889668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
BLDE University Journal of Health Sciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1