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Effectiveness of domiciliary rehabilitation, telerehabilitation, and home exercise program on pain, function, and quality of life in patients with total knee arthroplasty: A randomized controlled trial 居家康复、远程康复和家庭锻炼计划对全膝关节置换术患者疼痛、功能和生活质量的影响:一项随机对照试验
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_57_22
S. Kulkarni, S. Kulkarni, Arvind D. Patil, Shefali Painginkar
BACKGROUND: Knee osteoarthritis (OA) is the major source of disability worldwide. OA of knee is a joint disease that affects the elderly. It is characterized by progressive articular cartilage damage which further causes pain and loss of function. Total knee replacement (TKR) is the standard treatment for severe OA knee. Telerehabilitation is one of the new treatment ways and is speedily growing as an alternative for therapies. OBJECTIVES: The objective of this study was to compare the effects of domiciliary rehabilitation, telerehabilitation, and home exercise program on pain, function, and quality of life (QOL) in patients with TKR. MATERIALS AND METHODS: A total of 108 individuals were enrolled as per eligibility criteria during the study period and then were randomly divided into three groups by computer-generated, randomized sequence numbers. The parameters were obtained preoperatively, postoperatively, and at the end of 1 month using the Visual Analog Scale (VAS), Knee Injury and Osteoarthritis Outcome Score, Quality of Well-being, methadone maintenance treatment (MMT), and knee range of motion (ROM) test. P < 0.05 was considered statistically significant. RESULTS: All the three groups showed a reduction in VAS scores and improved function in patients with TKR. QOL and MMT did not prove to be significant in any of the three groups. When ROM was considered, only Groups A and C showed statistical significance whereas Groups A and B showed clinical significance according to the mean difference values. CONCLUSION: All the three modes of rehabilitation among OA patients, i.e., domiciliary rehabilitation, telerehabilitation, and home-based exercise program, have shown similar effects on study variables including pain intensity, knee function, and QOL in patients with TKR. Therefore, we recommend to include telerehabilitation as one of the treatment approaches for patients with TKR whenever needed.
背景:膝骨关节炎(OA)是世界范围内致残的主要原因。膝关节炎是一种影响老年人的关节疾病。它的特点是进行性关节软骨损伤,进一步引起疼痛和功能丧失。全膝关节置换术(TKR)是严重OA膝关节的标准治疗方法。远程康复是一种新的治疗方法,作为一种替代疗法正在迅速发展。目的:本研究的目的是比较居家康复、远程康复和家庭运动方案对TKR患者疼痛、功能和生活质量(QOL)的影响。材料与方法:在研究期间,根据入选标准共纳入108人,然后按计算机生成的随机序列号随机分为三组。采用视觉模拟量表(VAS)、膝关节损伤和骨关节炎结局评分、生活质量、美沙酮维持治疗(MMT)和膝关节活动范围(ROM)测试,分别在术前、术后和1个月结束时获得参数。P < 0.05为差异有统计学意义。结果:三组TKR患者VAS评分均降低,功能改善。QOL和MMT在三组中均无显著性差异。当考虑ROM时,只有A组和C组有统计学意义,而A组和B组根据平均差异值有临床意义。结论:OA患者的三种康复模式,即居家康复、远程康复和家庭运动计划,对TKR患者疼痛强度、膝关节功能和生活质量等研究变量均有相似的影响。因此,我们建议在必要时将远程康复作为TKR患者的治疗方法之一。
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引用次数: 0
Axillary lymphadenopathy in a case of breast carcinoma: Is it always metastatic? 乳腺癌腋窝淋巴结病1例:是否总是转移?
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_40_22
Padmini Vijayasarathy, P. Chikkannaiah, Netravati B Sajjan, Vani Ramalingaiah, S. Venkataramanappa
Cancer and tuberculosis are the most common illnesses in the world; however, their coexistence is not uncommon and a challenge for pathologists and clinicians. The instances of mucinous carcinoma and disseminated tuberculosis are exceptional. Here, we present such a rare case of incidentally detected mucinous carcinoma of the breast with disseminated miliary tuberculosis in a 59-year-old female. The pertinent literature is being reviewed.
癌症和肺结核是世界上最常见的疾病;然而,它们的共存并不罕见,对病理学家和临床医生来说是一个挑战。粘液癌和播散性肺结核是例外。在此,我们报告一例罕见的偶然发现的乳腺粘液癌合并播散性粟粒性结核的病例,患者为59岁女性。正在对相关文献进行审查。
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引用次数: 0
A tailor-made physical therapy protocol for a rare pediatric tumor 为罕见的儿童肿瘤量身定制的物理治疗方案
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_117_21
Renu B Pattanshetty, Nikita Pawar, Mounica Y. Rao
Solid pseudopapillary carcinoma of pancreas is a cystic exocrine tumor of the pancreas which is common in females in the third and fourth decades. This report presents a rare case of an 11-year-old girl who operated for Frantz tumor and was referred for physical therapy. The therapy was beneficial in reducing the pain, improving the range of motion, and overall quality of life of the patient. To the best of our knowledge, this is the first case report found in the medical literature that reports of physical therapy management in a rare reported case of pediatric solid pseudopapillary carcinoma of pancreas.
胰腺实性假乳头状癌是胰腺的囊性外分泌肿瘤,常见于30岁和40岁的女性。本文报告一例罕见的11岁女孩,因弗朗茨肿瘤而接受手术治疗。该疗法有助于减轻疼痛,改善活动范围,提高患者的整体生活质量。据我们所知,这是在医学文献中发现的第一个病例报告,报告了一个罕见的儿童胰腺实性假乳头状癌的物理治疗管理。
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引用次数: 0
Challenges faced by 1st phase MBBS students during online teaching of competency-based medical education curriculum – COVID times 第一阶段MBBS学生在能力本位医学教育课程在线教学中面临的挑战——新冠病毒时代
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_3_22
B. Sofia, S. Subhaprada
BACKGROUND: Competency-based medical education (CBME) is a learner-centered, outcome-based approach which motivates self-learning. Currently, the world is experiencing COVID-19 pandemic which led to shutdown of colleges, and hence, online teaching has become a key component in the continuity of medical education. The main aim of the study is to analyze the impact of COVID-19 pandemic on online teaching among 1st-year MBBS students and to assess the challenges faced during this time. METHODS: After obtaining institutional ethics committee clearance, a mixed-method study design was used to collect data from 100 respondents among 1st-year MBBS students of Kurnool Medical College, Kurnool, during the month of September 2020. A prevalidated, semi-structured questionnaire was sent to the participants through Google Forms. The quantitative analysis was done through survey questions on a five-point Likert scale. RESULTS: The reported challenges to online medical education during COVID-19 pandemic were lack of in-person communication (57%), technical issues while attending online classes (49%), difficulty in time management (50%), confusion in understanding course expectations/competencies (44%), and more focused on theory than practicals (59%). Some of them stated that “having online classes is really helpful than not having any classes at all.” CONCLUSIONS: Hence, we conclude that though challenges mentioned above were faced during online teaching of CBME curriculum, effective leadership and student teamwork would be helpful in successful online teaching.
背景:以能力为基础的医学教育(CBME)是一种以学习者为中心、以结果为基础的激励自我学习的方法。目前,全球正在经历新冠肺炎疫情,导致大学关闭,因此在线教学已成为医学教育连续性的关键组成部分。该研究的主要目的是分析COVID-19大流行对MBBS一年级学生在线教学的影响,并评估在此期间面临的挑战。方法:在获得机构伦理委员会的批准后,采用混合方法研究设计,于2020年9月从库尔努尔医学院一年级MBBS学生中收集100名受访者的数据。通过Google表单向参与者发送了一份预先验证的半结构化问卷。定量分析是通过李克特五分制的调查问题来完成的。结果:在COVID-19大流行期间,在线医学教育面临的挑战包括缺乏面对面交流(57%),参加在线课程时出现技术问题(49%),时间管理困难(50%),对课程期望/能力的理解混乱(44%),以及更注重理论而不是实践(59%)。他们中的一些人表示,“在线课程真的比不上课有帮助。”结论:尽管CBME课程在线教学面临上述挑战,但有效的领导和学生团队合作有助于在线教学的成功。
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引用次数: 0
Dental professional's understanding of COVID-19 management: Can they contribute to medical care? 牙科专业人员对COVID-19管理的理解:他们能否为医疗保健做出贡献?
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_29_22
A. Juneja, A. Sultan
BACKGROUND: The sudden appearance of the highly infectious novel coronavirus in December 2019 has created global havoc in a short time. In the present scenario where the cases are rising explosively and medical health care professionals are losing their lives to coronavirus disease 2019 (COVID-19), the role of dental surgeons needs to be redefined. OBJECTIVE: Keeping all these things into consideration; this questionnaire-based cross sectional survey was planned to understand how dental surgeons managed COVID-19 once they got infected, and how confident they are if in future they need to treat cases of COVID-19. MATERIALS AND METHODS: A cross-sectional survey was done to assess the knowledge of practising dental surgeons infected with COVID-19 of the disease and its management. RESULTS: One hundred and one respondents completed the questionnaire. Of those 81% were vaccinated while 19% were not vaccinated. Of these 50.5% felt confident that they had adequate knowledge regarding COVID-19 and can treat mild-to-moderate infections. 84.2% believed that short-term courses and workshops should be designed for dental surgeons to improve their knowledge, keeping in mind their future role in pandemic. CONCLUSION: Short-term courses need to be designed to improve the current knowledge of dental surgeons regarding COVID-19 and prepare them for future.
背景:2019年12月,传染性极强的新型冠状病毒突然出现,在短时间内造成了全球大破坏。在目前的情况下,病例呈爆炸式增长,医疗保健专业人员因2019冠状病毒病(COVID-19)而丧生,牙科医生的角色需要重新定义。目标:考虑所有这些因素;这项基于问卷的横断面调查旨在了解牙科外科医生在感染后如何处理COVID-19,以及他们将来是否需要治疗COVID-19病例的信心。材料与方法:采用横断面调查的方法对感染COVID-19的牙科执业外科医生的疾病知识及其处理情况进行评估。结果:1001名被调查者完成了问卷。其中81%接种了疫苗,19%没有接种。其中50.5%的人相信他们对COVID-19有足够的了解,并且可以治疗轻中度感染。84.2%的人认为,应为牙科医生设计短期课程和讲习班,以提高他们的知识,同时考虑到他们未来在大流行病中的作用。结论:需要设计短期课程,以提高当前牙科医生对COVID-19的认识,并为未来做好准备。
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引用次数: 0
A comprehensive review of Trivanga bhasma (herbomineral trimetallic formulation) Trivanga bhasma(草本三金属制剂)综述
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_108_21
Pravin Jawanjal, Swapnil Choudhary, P. Bedarkar, B. Patgiri
BACKGROUND: Trivanga Bhasma, a herbomineral formulation prepared by incineration of Vanga (Tin), Naga (Lead), Yashada (zinc). In Rasa Kaumudi Trivanga bhasma is mentioned as Triloha bhasma. AIM: The aim of the present study was analysis of various pharmaceutical methods, doses, indications, of Trivanga Bhasma mentioned in Ayurveda texts. INTRODUCTION: Trivanga Bhasma is indicated in MutraRoga (disorders of urine), Madhumeha (Diabetes) and Vandhyatva (Infertility), Napunasakta (Impotency), Shaktivardhaka (Strength) Swetapradara (Leucorrhea). METHODS: Ancient Ayurvedic classics included Rasatantrasara Evam Siddhaprayoga Sangraha, Ayurvedeeya Oushadi Gunadharma Shastra, Siddhayoga Sangraha, Rasa Kaumudi, Bhasma Vigyana, Rasa Raj Mahodadhi, and other available translations in various languages were viewed. Marana (incineration) method of Trivanga Bhasma mentioned in classics were collected and analyzed. A comprehensive review of Trivanga Bhasma has been attempted by searching of published literatures in various database including Web of Science, PubMed, Scopus, Taylor and Francis, Google Scholar, and University Grants Commission care journals list. DISCUSSION: In classical texts, fourteen methods of preparation of Trivanga Bhasma were found and in texts-Rasa Kaumudi-1, Rasayansara-2, SiddhaYoga Samgraha-1, Rasaraj Mahodadhi-1, Ayurvediya Aushadhi Guna Dharma Shastra-1, Rasatantra Sara Evam Siddha Prayoga Samgraha-2, Bhasma Vigyana-5, and Ayurvedic Formulary India-1 methods are mentioned. In these methods, 9 methods were Jarana followed by Putapaka, Jarana in 3 methods, Damaru Yantra Kramangi paka in 2 methods. CONCLUSION: A total of 14 methods of Marana with 22 media are mentioned for Trivanga Bhasma.
背景:Trivanga Bhasma是一种草本矿物配方,由焚烧Vanga(锡),Naga(铅),Yashada(锌)制成。在Rasa Kaumudi中,Trivanga bhasma被称为Triloha bhasma。目的:本研究的目的是分析阿育吠陀文献中提到的Trivanga Bhasma的各种药物方法,剂量,适应症。Trivanga Bhasma适用于MutraRoga(尿障碍),Madhumeha(糖尿病)和Vandhyatva(不孕症),Napunasakta(阳痿),Shaktivardhaka(力量)Swetapradara(白带)。方法:查阅古代阿育吠陀经典,包括《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》、《阿育吠陀经典》以及其他多种语言的译本。收集并分析了经典中提到的特里万加·巴斯马的焚烧法。通过检索Web of Science、PubMed、Scopus、Taylor and Francis、谷歌Scholar和University Grants Commission care journals list等数据库中已发表的文献,试图对Trivanga Bhasma进行全面的综述。讨论:在经典文献中,发现了十四种制备Trivanga Bhasma的方法,并在文献中提到了rasa Kaumudi-1, Rasayansara-2,悉达瑜伽Samgraha-1, Rasaraj Mahodadhi-1,阿育吠陀ya Aushadhi Guna Dharma Shastra-1, Rasatantra Sara Evam Siddha Prayoga Samgraha-2, Bhasma Vigyana-5和阿育吠陀处方印度-1方法。其中耆那乐法9种,其次是布塔帕卡法,耆那乐法3种,大摩衍持克拉马吉法2种。结论:共有14种马拉那方法,22种介质。
{"title":"A comprehensive review of Trivanga bhasma (herbomineral trimetallic formulation)","authors":"Pravin Jawanjal, Swapnil Choudhary, P. Bedarkar, B. Patgiri","doi":"10.4103/bjhs.bjhs_108_21","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_108_21","url":null,"abstract":"BACKGROUND: Trivanga Bhasma, a herbomineral formulation prepared by incineration of Vanga (Tin), Naga (Lead), Yashada (zinc). In Rasa Kaumudi Trivanga bhasma is mentioned as Triloha bhasma. AIM: The aim of the present study was analysis of various pharmaceutical methods, doses, indications, of Trivanga Bhasma mentioned in Ayurveda texts. INTRODUCTION: Trivanga Bhasma is indicated in MutraRoga (disorders of urine), Madhumeha (Diabetes) and Vandhyatva (Infertility), Napunasakta (Impotency), Shaktivardhaka (Strength) Swetapradara (Leucorrhea). METHODS: Ancient Ayurvedic classics included Rasatantrasara Evam Siddhaprayoga Sangraha, Ayurvedeeya Oushadi Gunadharma Shastra, Siddhayoga Sangraha, Rasa Kaumudi, Bhasma Vigyana, Rasa Raj Mahodadhi, and other available translations in various languages were viewed. Marana (incineration) method of Trivanga Bhasma mentioned in classics were collected and analyzed. A comprehensive review of Trivanga Bhasma has been attempted by searching of published literatures in various database including Web of Science, PubMed, Scopus, Taylor and Francis, Google Scholar, and University Grants Commission care journals list. DISCUSSION: In classical texts, fourteen methods of preparation of Trivanga Bhasma were found and in texts-Rasa Kaumudi-1, Rasayansara-2, SiddhaYoga Samgraha-1, Rasaraj Mahodadhi-1, Ayurvediya Aushadhi Guna Dharma Shastra-1, Rasatantra Sara Evam Siddha Prayoga Samgraha-2, Bhasma Vigyana-5, and Ayurvedic Formulary India-1 methods are mentioned. In these methods, 9 methods were Jarana followed by Putapaka, Jarana in 3 methods, Damaru Yantra Kramangi paka in 2 methods. CONCLUSION: A total of 14 methods of Marana with 22 media are mentioned for Trivanga Bhasma.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"40 2 1","pages":"198 - 203"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78011508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge and practice regarding menstrual hygiene and alternatives to sanitary pad among Indian undergraduate medical students: A cross-sectional study 印度医科大学生关于经期卫生和卫生巾替代品的知识和实践:一项横断面研究
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_2_22
Y. Nalini, Sonal Gaonkar, I. Anjusha, A. Basavarajegowda
INTRODUCTION: While the availability and use of disposable sanitary pads have increased considerably in the last two decades, awareness about disposal and menstrual waste management has been neglected. This study was designed to determine the knowledge and practice of sanitary pad usage, disposal, and alternative methods of menstrual hygiene attitude toward menstrual leave among Indian undergraduate medical students. MATERIALS AND METHODS: The study participants were Indian undergraduate medical students. Self-administered online questionnaires were utilized, using Google Forms that requested personal details, menstrual history, usage and disposal of the sanitary pad, alternatives to the sanitary pad, and opinions about paid menstrual leave or sick leave policy. Quantitative data were summarized using mean and standard deviation, whereas qualitative data were summarized using percentages and frequencies. Data collected were analyzed using SPSS software version 20. RESULTS: Four hundred sixty-four students participated in the study. The mean age at menarche was 13 years. Menstrual bleeding lasted an average of 5.2 ± 1.6 days. Cycle length was 21–35 days in 92% of cases. Approximately 42.9% of respondents reported dysmenorrhea. 98% reported using the sanitary pad; among them, 48% reported they use a single pad (nonbio-degradable pads) for more than 6 h, and the most common mode of disposal is by wrapping in a newspaper. Menstrual cup followed by tampons is common alternatives to the sanitary pad. 48.7% reported that sometimes menstruation keeps them away from colleges. Eighty-two percent expressed menstrual leave policy of 1–2 days would be a positive and welcome move. CONCLUSIONS: Knowledge about sanitary pad disposal and alternatives is adequate among Indian undergraduate medical students but what is inadequate is the practice. Emphasis should be made on strategies that can be adopted to prevent the dumping of unsorted disposed of unsafe menstrual waste across the landfills resulting in a global health issue.
简介:在过去二十年中,一次性卫生巾的供应和使用大大增加,但对处置和经期废物管理的认识却被忽视了。本研究旨在了解印度医科大学生对卫生巾使用、处置、月经卫生替代方法的认知与实践,以及对月经假的态度。材料与方法:研究对象为印度医科本科生。使用谷歌表格进行自我管理的在线问卷调查,询问个人详细信息、月经史、卫生巾的使用和处理、卫生巾的替代品以及对带薪月经假或病假政策的意见。定量数据采用均值和标准差进行汇总,定性数据采用百分比和频率进行汇总。收集的数据采用SPSS软件第20版进行分析。结果:464名学生参与了研究。初潮的平均年龄为13岁。月经出血时间平均为5.2±1.6 d。92%的病例周期长度为21 ~ 35天。约42.9%的受访者报告痛经。98%的人报告使用卫生巾;其中,48%的人表示,他们使用一个卫生巾(不可生物降解的卫生巾)超过6小时,最常见的处理方式是用报纸包裹。月经杯和卫生棉条是卫生巾的常见替代品。48.7%的人表示,有时月经会让他们远离大学。82%的人表示,1-2天的月经假政策将是积极和受欢迎的举措。结论:印度医科本科学生对卫生巾处理和替代品的认识是充分的,但实践是不足的。应强调可采取的战略,以防止在垃圾填埋场倾倒未经分类处理的不安全月经废物,从而造成全球健康问题。
{"title":"Knowledge and practice regarding menstrual hygiene and alternatives to sanitary pad among Indian undergraduate medical students: A cross-sectional study","authors":"Y. Nalini, Sonal Gaonkar, I. Anjusha, A. Basavarajegowda","doi":"10.4103/bjhs.bjhs_2_22","DOIUrl":"https://doi.org/10.4103/bjhs.bjhs_2_22","url":null,"abstract":"INTRODUCTION: While the availability and use of disposable sanitary pads have increased considerably in the last two decades, awareness about disposal and menstrual waste management has been neglected. This study was designed to determine the knowledge and practice of sanitary pad usage, disposal, and alternative methods of menstrual hygiene attitude toward menstrual leave among Indian undergraduate medical students. MATERIALS AND METHODS: The study participants were Indian undergraduate medical students. Self-administered online questionnaires were utilized, using Google Forms that requested personal details, menstrual history, usage and disposal of the sanitary pad, alternatives to the sanitary pad, and opinions about paid menstrual leave or sick leave policy. Quantitative data were summarized using mean and standard deviation, whereas qualitative data were summarized using percentages and frequencies. Data collected were analyzed using SPSS software version 20. RESULTS: Four hundred sixty-four students participated in the study. The mean age at menarche was 13 years. Menstrual bleeding lasted an average of 5.2 ± 1.6 days. Cycle length was 21–35 days in 92% of cases. Approximately 42.9% of respondents reported dysmenorrhea. 98% reported using the sanitary pad; among them, 48% reported they use a single pad (nonbio-degradable pads) for more than 6 h, and the most common mode of disposal is by wrapping in a newspaper. Menstrual cup followed by tampons is common alternatives to the sanitary pad. 48.7% reported that sometimes menstruation keeps them away from colleges. Eighty-two percent expressed menstrual leave policy of 1–2 days would be a positive and welcome move. CONCLUSIONS: Knowledge about sanitary pad disposal and alternatives is adequate among Indian undergraduate medical students but what is inadequate is the practice. Emphasis should be made on strategies that can be adopted to prevent the dumping of unsorted disposed of unsafe menstrual waste across the landfills resulting in a global health issue.","PeriodicalId":9122,"journal":{"name":"BLDE University Journal of Health Sciences","volume":"1 1","pages":"252 - 257"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88890860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A preliminary randomized, single-blinded, placebo-controlled clinical dose–response study to elucidate the effect of ongoing isometric contraction of muscles on the vital capacity of lungs on administering Blatta orientalis 一项初步的随机、单盲、安慰剂对照的临床剂量反应研究,旨在阐明给药东方布兰后持续等距肌肉收缩对肺肺活量的影响
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_46_22
Usha Kushwaha, G. Supriya, Balakrishnan Nair, K. Chattopadhyay, Ashwini Nair, Sanjay Vishwakarma
INTRODUCTION: Blatta orientalis is an indicated remedy for asthma and other chronic obstructive pulmonary diseases in homeopathic medicine. Preclinical studies indicate that B. orientalis shows anti-asthmatic properties in animals when induced with bronchospasm using acetylcholine through nonselective anticholinergic and antihistaminic activities. However, no studies have explored the changes in the vital capacity of the lungs on administering the homeopathic remedy, B. orientalis. It is shown that isometric contraction of pectoral muscles enhances the vital capacity of lungs by increasing ventilation and decreasing alveolar partial pressure of carbon dioxide. It can act as a valuable tool for monitoring the vital capacity of the lungs before and after administration of B. orientalis. AIM: This preliminary research takes the first step toward exploring vital capacity through a randomized, placebo-controlled study elucidating the effects of ongoing isometric contraction of muscles on the vital capacity of lungs of healthy individuals on the administration of B. orientalis in different potencies. It aims to compare changes in the vital capacity of lungs in healthy participants during an acute bout of isometric contraction by handgrip dynamometer after administration of B. orientalis. MATERIALS AND METHODS: Eighteen participants who fulfilled the inclusion criteria gave voluntary consent to participate in this research study. The research team measured the Tmax (measured by handgrip dynamometer) and the vital capacity (measured by a vitalograph) of these participants at the baseline. The participants were then placed into three-medicine arms to administer medicine orally: Arm 1 – B. orientalis Q, Arm 2 – B. orientalis 30C, and Arm 3 – placebo, following allocation of six participants in each medicine arm. Lottery method was used for grouping participants randomly to each medicine arm. The participants were numbered from 1 to 18 using the lottery method, and it was made sure that each arm had one male and five females to have similar gender distribution. The research team blindfolded the participants with a cloth bandage (dupatta) before categorizing them into different medicine arms. The team measured each participant's Tmax and vital capacity, and then administered one dose of the assigned medicine. The team measured the Tmax and vital capacity of the participants after 10 min of administering the medicine. The process was repeated after every 24 h for 3 consecutive days. RESULTS: The effect of ongoing isometric contractions of the skeletal muscles on the vital capacity acted as a great tool to measure improvement in vital capacity. The vital capacity of the lungs was significantly decreased after oral administration of B. orientalis Q and B. orientalis 30C, whereas there was no significant effect found in the arm that received a placebo. CONCLUSION: This preliminary study shows that B. orientalis decreases the vital capacity of lungs in healthy su
简介:东方布兰是顺势疗法药物中治疗哮喘和其他慢性阻塞性肺疾病的适应症药物。临床前研究表明,当乙酰胆碱诱导支气管痉挛时,东方蓟通过非选择性抗胆碱能和抗组胺活性表现出抗哮喘特性。然而,没有研究探索在使用顺势疗法药物B. orientalis时肺部肺活量的变化。结果表明,胸肌的等长收缩通过增加通气和降低肺泡二氧化碳分压来增强肺活量。它可以作为一个有价值的工具,监测肺的肺活量前后给药。目的:本初步研究通过一项随机、安慰剂对照研究,向探索肺活量迈出了第一步,阐明了不同剂量的东方蓟对健康个体持续等距肌肉收缩对肺活量的影响。它的目的是比较在健康参与者的肺活量的变化,在急性发作等距收缩后,由手握测力仪给药。材料与方法:18名符合纳入标准的受试者自愿同意参加本研究。研究小组在基线时测量了这些参与者的Tmax(用握力计测量)和肺活量(用生命记录仪测量)。然后,参与者被分为三种药物组,口服药物:第1组-东方B. Q,第2组-东方B. 30C,第3组-安慰剂,每个药物组分配6名参与者。采用抽签法将参与者随机分组到每个药物组。参与者使用摇号法从1到18编号,并确保每个手臂有一名男性和五名女性具有相似的性别分布。研究小组用布绷带蒙住参与者的眼睛,然后将他们分为不同的药物组。研究小组测量了每个参与者的Tmax和肺活量,然后给他们服用一剂指定的药物。研究小组在给药10分钟后测量了参与者的Tmax和肺活量。每隔24 h重复该过程,连续3天。结果:骨骼肌持续等长收缩对肺活量的影响是衡量肺活量改善的重要工具。口服B. orientalis Q和B. orientalis 30C后,肺的肺活量显著降低,而在接受安慰剂的手臂中没有发现明显的影响。结论:本初步研究表明,东方蓟具有降低健康人肺活量的作用,需要在更高的效价和更广泛的实验参数上进一步探索其作用。根据相似定律,这一推断也增加了顺势疗法药物在限制性肺疾病患者中潜力的研究范围,这些患者的重要肺活量明显下降。
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引用次数: 0
A bird's eye view on Kantakari Avaleha: A polyherbal Ayurveda formulation for bronchial asthma 鸟瞰Kantakari Avaleha:一种治疗支气管哮喘的阿育吠陀草药配方
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_61_21
S. Bhinde, Sonam S Bhinde, V. Kori, K. Patel
Avaleha (linctus) is a unique dosage form of Ayurveda pharmaceutics, which is frequently used in various disorders and especially in respiratory disorders. Kantakari Avaleha (KA) is one such formulation being used extensively for Shwasa (asthma) and Kasa (cough) along with its classical use in various other disorders too. Because of its demand in clinical settings, many pharmaceutical companies are also preparing this, and hence freely available in market. This review was carried out to get thorough idea related to its composition, method of preparation, and therapeutic uses along with its pharmaceutical standards. For this review, classical and compiled texts having subject of Ayurveda pharmaceutics were screened from Central Library of Institute of Teaching and Research in Ayurveda, Jamnagar. Out of total 15 texts screened, 7 texts had mentioned KA, and hence reviewed for its ingredients, dose, Anupana, and therapeutic uses. Synonyms, Rasapanchaka (Ayurveda principles of drug action), and Dosha Karma (therapeutic action) of ingredients were compiled from Bhavaprakasha Nighantu. Pharmaceutical parameters of KA were compiled from original research articles from peer-reviewed journals through Google Scholar, PubMed, ResearchGate, and J-Gate portal. After review, it was found that Acharya Sharangdhara (12th Century) had described this formulation for the first time. There are four variations available in formulation composition. Milk or water should be the Anupana for this drug as per Ayurvedic Formulary of India and Pharmacopoeia of India (API). Almost all references have recommended its use in Shwasa and Kasa, along with Arati (distress), Shula (colicky pain), Gulma (a type of lump), Hikka (hiccup), and Hradroga (heart disease) mentioned in one and the other classics. Maximum ingredients of this formulation possess hot potency (12 out of 18 drugs) and pungent biotransformation property (11 out of 18 drugs). As per available original research works, two laboratory samples and one market sample of KA had fulfilled almost all analytical parameters, mentioned in API. The current review work may be helpful as stepping stone for various researches on KA such as network pharmacology, in silico, pharmacology, and longitudinal cross-sectional, clinical study.
阿瓦莱哈是阿育吠陀药物的一种独特剂型,经常用于各种疾病,特别是呼吸系统疾病。Kantakari Avaleha (KA)就是一种这样的配方,广泛用于治疗哮喘和咳嗽,同时也用于治疗其他各种疾病。由于其在临床环境中的需求,许多制药公司也在制备它,因此可以在市场上免费获得。本文对其组成、制备方法、治疗用途及药物标准等方面进行了综述。为了进行这项审查,从贾姆纳格尔阿育吠陀教学和研究研究所中央图书馆筛选了具有阿育吠陀药学主题的经典和汇编文本。在总共筛选的15篇文章中,有7篇文章提到了KA,因此对其成分、剂量、Anupana和治疗用途进行了审查。同义词,Rasapanchaka(阿育吠陀药物作用原理)和Dosha Karma(治疗作用)成分汇编自Bhavaprakasha Nighantu。KA的药物参数来源于谷歌Scholar、PubMed、ResearchGate、J-Gate等同行评议期刊的原创研究文章。经考证,发现12世纪的阿查里亚·夏朗陀(Acharya Sharangdhara)首次描述了这一配方。在配方组成中有四种变体。根据印度阿育吠陀处方和印度药典(API),牛奶或水应该是这种药物的Anupana。几乎所有的参考文献都推荐它用于Shwasa和Kasa,以及Arati(痛苦),Shula(绞痛疼痛),Gulma(一种肿块),Hikka(打嗝)和Hradroga(心脏病)在一个和另一个经典中提到。该配方的最大成分具有热效(18种药物中的12种)和辛辣的生物转化特性(18种药物中的11种)。根据现有的原始研究工作,KA的两个实验室样品和一个市场样品几乎满足API中提到的所有分析参数。本文的综述工作可为今后网络药理学、计算机、药理学、纵向横断面、临床等方面的研究提供参考。
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引用次数: 0
Difficult airway management in a case of bilateral congenital torticollis 双侧先天性斜颈气道处理困难1例
Pub Date : 2022-07-01 DOI: 10.4103/bjhs.bjhs_74_22
C. Priyanka, S. Shanu, R. Brindha
Anatomical disorders of the head and neck pose a serious challenge to an anesthesiologist in terms of difficult intubation. Securing airway requires a detailed preanesthesia evaluation to assess any issues associated with the disease, especially concerning the airway. This is the case of a 46-year-old male with congenital bilateral torticollis posted for elective functional endoscopic sinus surgery. A detailed preanesthetic checkup was done and was anticipated a difficult airway situation, hence planned for an awake intubation. We performed a successful awake fiber-optic intubation. Excessive muscular atrophy and fibrosis characterize congenital bilateral torticollis, resulting in sternocleidomastoid tension and limited cervical motion. During intubation, asymmetry in the face caused a mismatch between the facial and cervical midlines, making sniffing difficult. Successful anesthetic management in a case of congenital bilateral torticollis requires thorough knowledge about the anatomical changes and also the expertise in fiber-optic bronchoscopy.
头部和颈部的解剖紊乱在插管困难方面对麻醉师提出了严峻的挑战。确保气道安全需要详细的麻醉前评估,以评估与疾病相关的任何问题,特别是关于气道的问题。这是一个46岁的男性先天性双侧斜颈的情况下,选择性功能性内窥镜鼻窦手术。进行了详细的麻醉前检查,预计气道情况困难,因此计划进行清醒插管。我们成功地进行了清醒光纤插管。先天性双侧斜颈的特征是过度的肌肉萎缩和纤维化,导致胸锁乳突肌紧张和颈部运动受限。在插管过程中,面部的不对称导致面部和颈部中线不匹配,使嗅探困难。在先天性双侧斜颈病例中,成功的麻醉管理需要对解剖变化的全面了解以及纤维支气管镜的专业知识。
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引用次数: 0
期刊
BLDE University Journal of Health Sciences
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